{"id":19056,"date":"2025-09-25T03:47:19","date_gmt":"2025-09-24T11:47:19","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/stem-cells\/stem-cell-therapy\/19056.html"},"modified":"2025-10-10T16:47:57","modified_gmt":"2025-10-10T08:47:57","slug":"%e9%97%b4%e5%85%85%e8%b4%a8%e5%b9%b2%e7%bb%86%e8%83%9evs%e7%a5%9e%e7%bb%8f%e5%b9%b2%e7%bb%86%e8%83%9e%ef%bc%9a%e6%b2%bb%e7%96%97%e8%84%8a%e9%ab%93%e6%8d%9f%e4%bc%a4%e5%93%aa%e7%a7%8d%e6%9b%b4%e6%9c%89","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html","title":{"rendered":"\u0647\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0648\u0633\u064a\u0637\u0629 \u0627\u0644\u0644\u064f\u0651\u062d\u0645\u064a\u0629 \u0623\u0643\u062b\u0631 \u0641\u0639\u0627\u0644\u064a\u0629 \u0641\u064a \u0639\u0644\u0627\u062c \u0625\u0635\u0627\u0628\u0627\u062a \u0627\u0644\u062d\u0628\u0644 \u0627\u0644\u0634\u0648\u0643\u064a\u061f \u0623\u0645 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class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194716-68d3da44eb453.png\" alt=\"\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u66f4\u6709\u6548\uff1f\u8fd8\u662f\u795e\u7ecf\u5e72\u7ec6\u80de\uff1f\" width=\"1536\" height=\"864\" title=\"\"><\/figure>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg 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href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E6%9B%B4%E6%9C%89%E6%95%88%EF%BC%9F%E8%BF%98%E6%98%AF%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9F\" >\u0647\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0648\u0633\u064a\u0637\u0629 \u0627\u0644\u0644\u064f\u0651\u062d\u0645\u064a\u0629 \u0623\u0643\u062b\u0631 \u0641\u0639\u0627\u0644\u064a\u0629 \u0641\u064a \u0639\u0644\u0627\u062c \u0625\u0635\u0627\u0628\u0627\u062a \u0627\u0644\u062d\u0628\u0644 \u0627\u0644\u0634\u0648\u0643\u064a\u061f \u0623\u0645 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629\u061f<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#%E4%B8%80%E3%80%81%E5%B9%B2%E7%BB%86%E8%83%9E%E7%B1%BB%E5%9E%8B%E6%A6%82%E8%BF%B0\" >\u4e00\u3001\u5e72\u7ec6\u80de\u7c7b\u578b\u6982\u8ff0<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#11_%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E\" >1.1 \u95f4\u5145\u8d28\u5e72\u7ec6\u80de<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#12_%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E\" >1.2 \u795e\u7ecf\u5e72\u7ec6\u80de<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#%E4%BA%8C%E3%80%81%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6%E5%AF%B9%E6%AF%94\" >\u4e8c\u3001\u4f5c\u7528\u673a\u5236\u5bf9\u6bd4<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#21_%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E4%B8%BB%E8%A6%81%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\" >2.1 \u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7684\u4e3b\u8981\u4f5c\u7528\u673a\u5236<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#22_%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E4%B8%BB%E8%A6%81%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\" >2.2 \u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u4e3b\u8981\u4f5c\u7528\u673a\u5236<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#%E4%B8%89%E3%80%81%E4%B8%B4%E5%BA%8A%E4%B8%8E%E5%AE%9E%E9%AA%8C%E7%A0%94%E7%A9%B6%E6%95%B0%E6%8D%AE%E8%AF%81%E6%8D%AE%E5%AF%B9%E6%AF%94\" >\u4e09\u3001\u4e34\u5e8a\u4e0e\u5b9e\u9a8c\u7814\u7a76\u6570\u636e\u8bc1\u636e\u5bf9\u6bd4<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#31_%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E6%82%A3%E8%80%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E6%95%B0%E6%8D%AE\" >3.1 \u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u7684\u4e34\u5e8a\u6570\u636e<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#32_%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E6%82%A3%E8%80%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E6%95%B0%E6%8D%AE\" >3.2 \u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u7684\u4e34\u5e8a\u6570\u636e<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#33_%E7%9B%B4%E6%8E%A5%E5%AF%B9%E6%AF%94%E4%B8%8E%E7%BB%BC%E5%90%88%E5%88%86%E6%9E%90\" >3.3 \u76f4\u63a5\u5bf9\u6bd4\u4e0e\u7efc\u5408\u5206\u6790<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19056.html\/#%E6%80%BB%E7%BB%93%E4%B8%8E%E5%B1%95%E6%9C%9B%E2%80%8B\" >\u603b\u7ed3\u4e0e\u5c55\u671b\u200b<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E6%9B%B4%E6%9C%89%E6%95%88%EF%BC%9F%E8%BF%98%E6%98%AF%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9F\"><\/span>\u0647\u0644 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0648\u0633\u064a\u0637\u0629 \u0627\u0644\u0644\u064f\u0651\u062d\u0645\u064a\u0629 \u0623\u0643\u062b\u0631 \u0641\u0639\u0627\u0644\u064a\u0629 \u0641\u064a \u0639\u0644\u0627\u062c \u0625\u0635\u0627\u0628\u0627\u062a \u0627\u0644\u062d\u0628\u0644 \u0627\u0644\u0634\u0648\u0643\u064a\u061f \u0623\u0645 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629\u061f<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<h2><span class=\"ez-toc-section\" id=\"%E4%B8%80%E3%80%81%E5%B9%B2%E7%BB%86%E8%83%9E%E7%B1%BB%E5%9E%8B%E6%A6%82%E8%BF%B0\"><\/span>\u4e00\u3001\u5e72\u7ec6\u80de\u7c7b\u578b\u6982\u8ff0<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"11_%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E\"><\/span>1.1 \u95f4\u5145\u8d28\u5e72\u7ec6\u80de<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>\u6765\u6e90\u200b<\/strong>\u200b\uff1aMSCs\u662f\u4e00\u79cd\u4e2d\u80da\u5c42\u6765\u6e90\u7684\u591a\u80fd\u6210\u4f53\u5e72\u7ec6\u80de\uff0c\u200b\u200b\u83b7\u53d6\u6765\u6e90\u5e7f\u6cdb\u200b\u200b\uff0c\u5305\u62ec\u9aa8\u9ad3\u3001\u8102\u80aa\u7ec4\u7ec7\u3001\u8110\u5e26\u548c\u80ce\u76d8\u7b49\u3002\u5176\u4e2d\uff0c\u8110\u5e26\u6765\u6e90\u7684MSCs\uff08UC-MSCs\uff09\u56e0\u589e\u6b96\u80fd\u529b\u5f3a\u3001\u514d\u75ab\u539f\u6027\u4f4e\u4e14\u65e0\u4f26\u7406\u4e89\u8bae\uff0c\u5728\u4e34\u5e8a\u5e94\u7528\u4e2d\u5907\u53d7\u9752\u7750\u3002<\/p>\n<p>\u200b<strong>\u200b\u57fa\u672c\u7279\u6027\u200b<\/strong>\u200b\uff1aMSCs\u7684\u6838\u5fc3\u4f18\u52bf\u5e76\u975e\u76f4\u63a5\u5206\u5316\u4e3a\u795e\u7ecf\u7ec6\u80de\uff0c\u800c\u5728\u4e8e\u5176\u5f3a\u5927\u7684\u200b\u200b\u514d\u75ab\u8c03\u8282\u200b\u200b\u548c\u200b\u200b\u65c1\u5206\u6ccc\u529f\u80fd\u200b\u200b\u3002\u5b83\u4eec\u80fd\u5206\u6ccc\u591a\u79cd\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff08\u5982BDNF\u3001GDNF\uff09\u3001\u6297\u708e\u56e0\u5b50\uff08\u5982IL-10\uff09\u548c\u4fc3\u8840\u7ba1\u751f\u6210\u56e0\u5b50\uff08\u5982VEGF\uff09\uff0c\u4ece\u800c\u6539\u5584\u635f\u4f24\u5fae\u73af\u5883\u3001\u6291\u5236\u51cb\u4ea1\u3001\u4fc3\u8fdb\u5185\u6e90\u6027\u4fee\u590d\u3002\u6b64\u5916\uff0cMSCs\u6613\u4e8e\u5728\u4f53\u5916\u6269\u589e\uff0c\u53ef\u8fdb\u884c\u81ea\u4f53\u79fb\u690d\uff0c\u907f\u514d\u4e86\u514d\u75ab\u6392\u65a5\u95ee\u9898<\/p>\n<h3><span class=\"ez-toc-section\" id=\"12_%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E\"><\/span>1.2 \u795e\u7ecf\u5e72\u7ec6\u80de<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>\u6765\u6e90\u200b<\/strong>\u200b\uff1aNSCs\u662f\u5b58\u5728\u4e8e\u795e\u7ecf\u7cfb\u7edf\u4e2d\u7684\u4e00\u7c7b\u5e72\u7ec6\u80de\uff0c\u53ef\u76f4\u63a5\u4ece\u200b\u200b\u80ce\u513f\u8111\u6216\u810a\u9ad3\u7ec4\u7ec7\u200b\u200b\u4e2d\u83b7\u53d6\u3002\u7136\u800c\uff0c\u968f\u7740\u91cd\u7f16\u7a0b\u6280\u672f\u7684\u53d1\u5c55\uff0c\u901a\u8fc7\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSCs\uff09\u5b9a\u5411\u5206\u5316\u4e3aNSCs\u5df2\u6210\u4e3a\u4e3b\u6d41\u8d8b\u52bf\uff0c\u8fd9\u4e0d\u4ec5\u89e3\u51b3\u4e86\u4f26\u7406\u95ee\u9898\uff0c\u8fd8\u4e3a\u5b9e\u73b0\u201c\u73b0\u8d27\u578b\u201d\u7ec6\u80de\u6cbb\u7597\u63d0\u4f9b\u4e86\u53ef\u80fd\u3002<\/p>\n<p>\u200b<strong>\u200b\u57fa\u672c\u7279\u6027\u200b<\/strong>\u200b\uff1aNSCs\u7684\u6838\u5fc3\u80fd\u529b\u662f\u200b\u200b\u591a\u5411\u5206\u5316\u6f5c\u80fd\u200b\u200b\uff0c\u5b83\u80fd\u76f4\u63a5\u5206\u5316\u4e3a\u6784\u6210\u795e\u7ecf\u7cfb\u7edf\u7684\u4e09\u5927\u7c7b\u7ec6\u80de\uff1a\u795e\u7ecf\u5143\u3001\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\u548c\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u3002\u56e0\u6b64\uff0cNSCs\u79fb\u690d\u65e8\u5728\u76f4\u63a5\u200b\u200b\u66ff\u4ee3\u53d7\u635f\u7684\u795e\u7ecf\u7ec6\u80de\u200b\u200b\uff0c\u91cd\u5efa\u795e\u7ecf\u73af\u8def\uff0c\u5e76\u4fc3\u8fdb\u9ad3\u9798\u518d\u751f\u4ee5\u6062\u590d\u4fe1\u53f7\u4f20\u5bfc\u3002<\/p>\n<figure class=\"wp-block-table is-style-stripes\">\n<table class=\"has-fixed-layout\" style=\"width: 56.6609%; height: 216px;\">\n<thead>\n<tr style=\"height: 24px;\">\n<th style=\"height: 24px;\"><strong>\u7279\u6027<\/strong><\/th>\n<th style=\"height: 24px; text-align: center;\"><strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09<\/strong><\/th>\n<th style=\"height: 24px;\"><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSC\uff09<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"height: 48px;\">\n<td style=\"height: 48px;\"><strong>\u4e3b\u8981\u6765\u6e90<\/strong><\/td>\n<td style=\"height: 48px;\">\u9aa8\u9ad3\u3001\u8102\u80aa\u3001\u8110\u5e26<\/td>\n<td style=\"height: 48px;\">\u80ce\u513f\u795e\u7ecf\u7ec4\u7ec7\u3001iPSC\u5206\u5316<\/td>\n<\/tr>\n<tr style=\"height: 48px;\">\n<td style=\"height: 48px;\"><strong>\u5206\u5316\u6f5c\u80fd<\/strong><\/td>\n<td style=\"height: 48px;\">\u6709\u9650\u795e\u7ecf\u5206\u5316\uff0c\u4e3b\u8981\u5206\u5316\u4e3a\u652f\u6301\u7ec6\u80de<\/td>\n<td style=\"height: 48px;\">\u53ef\u5206\u5316\u4e3a\u795e\u7ecf\u5143\u3001\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\u3001\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de<\/td>\n<\/tr>\n<tr style=\"height: 48px;\">\n<td style=\"height: 48px;\"><strong>\u4e3b\u8981\u673a\u5236<\/strong><\/td>\n<td style=\"height: 48px;\">\u514d\u75ab\u8c03\u8282\u3001\u5206\u6ccc\u795e\u7ecf\u8425\u517b\u56e0\u5b50\u3001\u4fc3\u8fdb\u8840\u7ba1\u751f\u6210<\/td>\n<td style=\"height: 48px;\">\u66ff\u4ee3\u53d7\u635f\u795e\u7ecf\u5143\u3001\u91cd\u5efa\u795e\u7ecf\u7f51\u7edc\u3001\u5f62\u6210\u9ad3\u9798<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px;\"><strong>\u4f18\u52bf<\/strong><\/td>\n<td style=\"height: 24px;\">\u514d\u75ab\u539f\u6027\u4f4e\u3001\u6613\u4e8e\u83b7\u53d6\u3001\u5b89\u5168\u6027\u8f83\u597d<\/td>\n<td style=\"height: 24px;\">\u795e\u7ecf\u5b9a\u5411\u5206\u5316\u80fd\u529b\u5f3a\u3001\u6574\u5408\u6548\u7387\u9ad8<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"height: 24px;\"><strong>\u5c40\u9650\u6027<\/strong><\/td>\n<td style=\"height: 24px;\">\u795e\u7ecf\u5206\u5316\u80fd\u529b\u6709\u9650<\/td>\n<td style=\"height: 24px;\">\u6765\u6e90\u53d7\u9650\u3001\u4f26\u7406\u4e89\u8bae<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<h2><span class=\"ez-toc-section\" id=\"%E4%BA%8C%E3%80%81%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6%E5%AF%B9%E6%AF%94\"><\/span>\u4e8c\u3001\u4f5c\u7528\u673a\u5236\u5bf9\u6bd4<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"21_%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E4%B8%BB%E8%A6%81%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\"><\/span>2.1 \u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7684\u4e3b\u8981\u4f5c\u7528\u673a\u5236<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>MSCs\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u4e3b\u8981\u673a\u5236\u4e0d\u4ec5\u9650\u4e8e\u5206\u5316\u66ff\u4ee3\uff0c\u800c\u662f\u901a\u8fc7\u591a\u91cd\u65c1\u5206\u6ccc\u6548\u5e94\u5b9e\u73b0\uff1a<\/p>\n<p><strong>\u6297\u708e\u4f5c\u7528<\/strong>\uff1a\u8c03\u8282\u5c0f\u80f6\u8d28\u7ec6\u80de\u4ece\u4fc3\u708eM1\u578b\u5411\u6297\u708eM2\u578b\u8f6c\u5316\uff0c\u964d\u4f4e\u80bf\u7624\u574f\u6b7b\u56e0\u5b50-\u03b1\uff08TNF-\u03b1\uff09\u548c\u767d\u4ecb\u7d20-1\u03b2\uff08IL-1\u03b2\uff09\u7b49\u708e\u6027\u56e0\u5b50\u6c34\u5e73\uff0c\u51cf\u8f7b\u7ee7\u53d1\u6027\u635f\u4f24\uff1b<\/p>\n<p><strong>\u5206\u6ccc\u751f\u957f\u56e0\u5b50<\/strong>\uff1a\u4ea7\u751f\u591a\u79cd\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff0c\u5982BDNF\u3001GDNF\u548cNGF\uff0c\u4fc3\u8fdb\u795e\u7ecf\u5143\u5b58\u6d3b\u548c\u8f74\u7a81\u518d\u751f\uff1b<\/p>\n<p><strong>\u4fc3\u8fdb\u8840\u7ba1\u751f\u6210<\/strong>\uff1a\u901a\u8fc7\u5206\u6cccVEGF\u548cAngiopoietin-1\u7b49\u56e0\u5b50\uff0c\u6539\u5584\u635f\u4f24\u5c40\u90e8\u8840\u6db2\u4f9b\u5e94\uff0c\u4e3a\u795e\u7ecf\u4fee\u590d\u63d0\u4f9b\u8425\u517b\u652f\u6301\uff1b<\/p>\n<p><strong>\u51cf\u5c11\u7ec6\u80de\u51cb\u4ea1<\/strong>\uff1a\u6291\u5236Caspase-3\u7b49\u51cb\u4ea1\u76f8\u5173\u86cb\u767d\u8868\u8fbe\uff0c\u4fdd\u62a4\u53d7\u635f\u4f46\u5c1a\u672a\u6b7b\u4ea1\u7684\u795e\u7ecf\u7ec6\u80de\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"22_%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E4%B8%BB%E8%A6%81%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\"><\/span>2.2 \u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u4e3b\u8981\u4f5c\u7528\u673a\u5236<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>NSCs\u5219\u4e3b\u8981\u901a\u8fc7\u76f4\u63a5\u66ff\u4ee3\u548c\u7ed3\u6784\u91cd\u5efa\u53d1\u6325\u4f5c\u7528\uff1a<\/p>\n<p><strong>\u66ff\u4ee3\u53d7\u635f\u795e\u7ecf\u5143<\/strong>\uff1a\u5206\u5316\u4e3a\u529f\u80fd\u6027\u795e\u7ecf\u5143\uff0c\u66ff\u4ee3\u56e0\u635f\u4f24\u800c\u6b7b\u4ea1\u7684\u795e\u7ecf\u7ec6\u80de\uff0c\u76f4\u63a5\u53c2\u4e0e\u795e\u7ecf\u4fe1\u53f7\u4f20\u5bfc\u3002\u7814\u7a76\u8868\u660e\uff0c\u79fb\u690d\u7684NSCs\u53ef\u5206\u5316\u4e3a\u8fd0\u52a8\u795e\u7ecf\u5143\uff08\u536016%\uff09\u3001V2\u4e2d\u95f4\u795e\u7ecf\u5143\uff08\u536011%\uff09\u548cdI4\u4e2d\u95f4\u795e\u7ecf\u5143\uff08\u536029.4%\uff09\u7b49\u591a\u79cd\u529f\u80fd\u7ec6\u80de\uff1b<\/p>\n<p><strong>\u4fc3\u8fdb\u795e\u7ecf\u7f51\u7edc\u91cd\u5efa<\/strong>\uff1a\u5ef6\u4f38\u795e\u7ecf\u7ea4\u7ef4\u4e0e\u5bbf\u4e3b\u795e\u7ecf\u5143\u5f62\u6210<strong>\u7a81\u89e6\u8fde\u63a5<\/strong>\uff0c\u91cd\u5efa\u795e\u7ecf\u4fe1\u53f7\u901a\u8def\u3002\u514d\u75ab\u8367\u5149\u67d3\u8272\u8bc1\u5b9e\uff0c\u79fb\u690d\u7ec6\u80de\u8868\u8fbe\u7684\u4eba\u7279\u5f02\u6027\u7a81\u89e6\u86cb\u767d\uff08hSyn\uff09\u4e0e\u5bbf\u4e3b\u795e\u7ecf\u6807\u5fd7\u7269\uff08MAP2\uff09\u5b58\u5728\u5171\u5b9a\u4f4d\uff0c\u8868\u660e\u771f\u6b63\u5b9e\u73b0\u4e86\u201d\u4fe1\u53f7\u4e92\u901a\u201d\uff1b<\/p>\n<p><strong>\u5f62\u6210\u9ad3\u9798<\/strong>\uff1a\u5206\u5316\u4e3a\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\uff0c\u5305\u7ed5\u53d7\u635f\u8f74\u7a81\u5f62\u6210\u9ad3\u9798\uff0c\u6062\u590d\u795e\u7ecf\u4f20\u5bfc\u901f\u5ea6\uff1b<\/p>\n<p><strong>\u8c03\u8282\u5fae\u73af\u5883<\/strong>\uff1a\u6700\u65b0\u7814\u7a76\u53d1\u73b0\uff0cNSCs\u540c\u6837\u5177\u6709\u8c03\u8282\u635f\u4f24\u5c40\u90e8\u5fae\u73af\u5883\u7684\u80fd\u529b\uff0c\u53ef\u6291\u5236\u80f6\u8d28\u7622\u75d5\u5f62\u6210\uff0c\u4e3a\u8f74\u7a81\u518d\u751f\u201d\u6253\u5f00\u901a\u9053\u201d\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%B8%89%E3%80%81%E4%B8%B4%E5%BA%8A%E4%B8%8E%E5%AE%9E%E9%AA%8C%E7%A0%94%E7%A9%B6%E6%95%B0%E6%8D%AE%E8%AF%81%E6%8D%AE%E5%AF%B9%E6%AF%94\"><\/span>\u4e09\u3001\u4e34\u5e8a\u4e0e\u5b9e\u9a8c\u7814\u7a76\u6570\u636e\u8bc1\u636e\u5bf9\u6bd4<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"31_%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E6%82%A3%E8%80%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E6%95%B0%E6%8D%AE\"><\/span>3.1 \u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u7684\u4e34\u5e8a\u6570\u636e<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>2025\u5e743\u67086\u65e5\uff0c\u201c\u56fd\u5bb6\u4e24\u59d4\u5907\u6848\u5e72\u7ec6\u80de\u4e34\u5e8a\u7814\u7a76\u00b7\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u62db\u52df\u201d\u5a92\u4f53\u53d1\u5e03\u4f1a\u53ec\u5f00\uff0c\u897f\u5b89\u533b\u9662\u6b63\u5f0f\u542f\u52a8\u4e86<strong>\u897f\u5317\u5730\u533a\u9996\u4e2a\u4e2d\u67a2\u795e\u7ecf\u635f\u4f24\u5e72\u7ec6\u80de\u9879\u76ee<\/strong>\u3002\u8be5\u9879\u76ee\u65e8\u5728\u901a\u8fc7<strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24<\/strong>\uff0c\u6807\u5fd7\u7740\u4ece\u201c\u4e0d\u53ef\u9006\u201d\u635f\u4f24\u5230\u201c\u529f\u80fd\u91cd\u5efa\u201d\u7684\u91cd\u8981\u4e34\u5e8a\u7a81\u7834\u3002<sup>[1]<\/sup><\/p>\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194717-68d3da45dd4fa.png\" alt=\"\" title=\"\"><\/figure>\n<p>\u5728\u53d1\u5e03\u4f1a\u4e0a\uff0c\u9662\u957f\u8be6\u7ec6\u4ecb\u7ecd\u4e86\u201c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u201d\u9879\u76ee\u7684\u7533\u62a5\u80cc\u666f\u53ca\u8fc7\u7a0b\u3002\u4ed6\u6307\u51fa\uff0c<strong>\u8bd5\u4e86\u624b\u672f\u3001\u836f\u7269\u7b49\u5f88\u591a\u65b9\u6cd5\uff0c\u591a\u5e74\u6765\u75c5\u60c5\u59cb\u7ec8\u6ca1\u6709\u8fdb\u5c55\uff0c\u505c\u7559\u5728\u540c\u4e00\u7597\u6548\u4e0a\u3002\u4f20\u7edf\u6cbb\u7597\u624b\u6bb5\u4ec5\u80fd\u901a\u8fc7\u624b\u672f\u51cf\u538b\u6e05\u7406\u635f\u4f24\u90e8\u4f4d\uff0c\u5374\u65e0\u6cd5\u5b9e\u73b0\u795e\u7ecf\u4fe1\u53f7\u901a\u8def\u7684\u518d\u751f\u4fee\u590d<\/strong>\u3002<\/p>\n<p>\u57fa\u4e8e\u6b64\uff0c\u8d3a\u9662\u957f\u5e26\u9886\u56e2\u961f\u5f00\u542f\u4e86\u5e72\u7ec6\u80de\u7597\u6cd5\u7684\u7814\u7a76\uff0c\u5e0c\u671b\u901a\u8fc7\u7cbe\u51c6\u7684\u5e72\u7ec6\u80de\u79fb\u690d\u6280\u672f\uff0c\u91cd\u5efa\u53d7\u635f\u795e\u7ecf\u7cfb\u7edf\u7684\u201c\u901a\u4fe1\u7f51\u7edc\u201d\uff0c\u4e3a\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7597\u9014\u5f84\u3002<\/p>\n<p>\u5f20\u4f1f\u4e3b\u4efb\u5728\u4f1a\u4e0a\u5206\u4eab\u4e86\u9879\u76ee\u7684\u521d\u6b65\u6210\u679c\uff1a\u53c2\u4e0e\u4e34\u5e8a\u7814\u7a76\u76846\u540d\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u4e2d\uff0c<strong>5\u4f8b\u60a3\u8005\u51fa\u73b0\u4e86\u795e\u7ecf\u529f\u80fd\u7684\u6539\u5584\uff0c4\u4f8b\u60a3\u8005\u8fd0\u52a8\u529f\u80fd\u663e\u8457\u63d0\u5347\uff0c\u5176\u4e2d2\u4f8b\u60a3\u8005\u7684\u6062\u590d\u60c5\u51b5\u5c24\u4e3a\u7a81\u51fa<\/strong>\u3002\u4e00\u4f4d\u5b8c\u5168\u6027\u635f\u4f24\u60a3\u8005\u5728\u63a5\u53d7\u6cbb\u7597\u540e\uff0c\u5df2\u7ecf\u80fd\u591f\u5728\u8f85\u52a9\u4e0b\u77ed\u6682\u7ad9\u7acb\uff0c\u8fd9\u8868\u660e\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u5177\u6709\u53ef\u884c\u6027\uff0c\u5e76\u4e3a\u8fdb\u4e00\u6b65\u7684\u4e34\u5e8a\u8bd5\u9a8c\u63d0\u4f9b\u4e86\u6709\u529b\u4f9d\u636e\u3002<\/p>\n<p>\u5c71\u897f\u4e00\u540d22\u5c81\u7684\u810a\u9ad3\u635f\u4f24\u60a3\u8005\uff0c\u56e0\u9ad8\u7a7a\u5760\u843d\u540e\u53ea\u80fd\u5750\u8f6e\u6905\uff0c\u4e0b\u80a2\u6301\u7eed\u6253\u98a4\u62bd\u52a8\uff0c\u8fde\u5728\u5e8a\u4e0a\u5750\u90fd\u56f0\u96be\u3002<strong>\u8fdb\u884c\u4e86\u5e72\u7ec6\u80de\u79fb\u690d\u672f\u540e\uff0c\u4e0b\u80a2\u808c\u8089\u9010\u6e10\u6709\u52b2\uff0c\u73b0\u5728\u5df2\u7ecf\u80fd\u81ea\u884c\u6eda\u80cc\u548c\u8dea\u7acb\u4e86<\/strong>\u3002<\/p>\n<p>\u53e6\u4e00\u4f4d\u810a\u9ad3\u635f\u4f24\u60a3\u8005\uff0c\u5e73\u65f6\u8d70\u8def\u53ea\u80fd\u501f\u52a9\u4e8e\u62d0\u6756\uff0c\u5728\u7ec6\u80de\u79fb\u690d\u672f\u540e\u4e00\u4e2a\u6708\uff0c<strong>\u4ed6\u5df2\u7ecf\u80fd\u6254\u6389\u62d0\u6756\u8f7b\u677e\u8d70\u8def\u4e86<\/strong>\u3002<\/p>\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194718-68d3da466c612.png\" alt=\"\" title=\"\"><\/figure>\n<h3><span class=\"ez-toc-section\" id=\"32_%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E6%82%A3%E8%80%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E6%95%B0%E6%8D%AE\"><\/span>3.2 \u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u7684\u4e34\u5e8a\u6570\u636e<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>2024\u5e7412\u670817\u65e5\uff0c\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u533b\u5b66\u9662\u7814\u7a76\u4eba\u5458\u5728\u884c\u4e1a\u671f\u520a\u300a\u7ec6\u80de\u533b\u5b66\u62a5\u544a\u300b\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u5173\u4e8e\u300a\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u80f8\u690e\u635f\u4f24\u7684\u5355\u4e2d\u5fc3\u2160\u671f\u4e34\u5e8a\u7814\u7a76\u300b\u7684\u957f\u671f\u4e34\u5e8a\u548c\u5b89\u5168\u6027\u7ed3\u679c\u3002<sup>[2]<\/sup><\/p>\n<p>\u672c\u6b21\u53d1\u5e03\u7684I\u671f\u4e34\u5e8a\u7814\u7a76\u65e8\u5728\u8bc4\u4f30<strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u80f8\u690e\u810a\u9ad3\u635f\u4f24\u7684\u5b89\u5168\u6027\u548c\u521d\u6b65\u7597\u6548<\/strong>\u3002\u7814\u7a76\u9009\u53d6\u4e86\u56db\u540d\u5b8c\u5168\u6027ASIA-A\u7ea7\u80f8\u90e8SCI\u60a3\u8005\u4f5c\u4e3a\u53d7\u8bd5\u8005\uff0c\u8fd9\u4e9b\u60a3\u8005\u7684\u635f\u4f24\u65f6\u95f4\u5747\u8d85\u8fc7\u4e00\u5e74\uff0c\u4e14\u5728\u63a5\u53d7\u4efb\u4f55\u5176\u4ed6\u5f62\u5f0f\u7684\u6709\u6548\u6cbb\u7597\u540e\u4ecd\u672a\u89c1\u660e\u663e\u597d\u8f6c\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194718-68d3da4684ce6.webp\" alt=\"\" title=\"\"><figcaption><\/figcaption><\/figure>\n<p>\u6bcf\u4f4d\u53d7\u8bd5\u8005\u63a5\u53d7\u4e86\u6bcf\u4e2a\u6ce8\u5c04\u70b9\u542b\u67092\u00d710<sup>5<\/sup>\u4e2a\u795e\u7ecf\u5e72\u7ec6\u80de\uff0c\u901a\u8fc7\u5b9a\u5236\u7684\u7acb\u4f53\u5b9a\u5411\u8bbe\u5907\uff0c\u53cc\u4fa7\u6ce8\u5165\u635f\u4f24\u90e8\u4f4d\u5468\u56f4\u7684\u5269\u4f59\u7ec4\u7ec7\u53ca\u4e0b\u65b9\u7ea6\u4e00\u4e2a\u8282\u6bb5\u7684\u5185\u4fa7\u767d\u8d28\u533a\uff0c\u6574\u4e2a\u8fc7\u7a0b\u7531\u672f\u4e2d\u8367\u5149\u900f\u89c6\u6210\u50cf\u6307\u5bfc\u5b8c\u6210\u3002<\/p>\n<p><strong>\u4e34\u5e8a\u7ed3\u679c\uff1a<\/strong><\/p>\n<p><strong>1.\u795e\u7ecf\u7cfb\u7edf\u53cd\u5e94\u6982\u89c8\uff1a<\/strong>\u6309ISNCSCI\u968f\u8bbf\uff0c2\u540d\u53d7\u8bd5\u8005\uff08001\u3001010\uff09\u5728\u79fb\u690d\u540e\u51fa\u73b0\u4e86\u660e\u663e\u7684\u795e\u7ecf\u5b66\u6539\u5584\uff1a001\u5728\u79fb\u690d\u540e2\u5e74\u66fe\u4e0a\u5347\u4e24\u4e2a\u8282\u6bb5\uff0c5\u5e74\u56de\u843d\u81f3\u4e0a\u53471\u4e2a\u8282\u6bb5\uff1b010\u5219\u5728\u6574\u4e2a5\u5e74\u968f\u8bbf\u671f\u95f4\u4fdd\u6301\u4e86\u7a33\u5b9a\u7684\u795e\u7ecf\u529f\u80fd\u63d0\u5347\u3002<\/p>\n<p><strong>2.\u514d\u75ab\u6291\u5236\u4e0e\u514d\u75ab\u53cd\u5e94\uff1a<\/strong>\u56db\u540d\u53d7\u8bd5\u8005\u5747\u5728\u79fb\u690d\u540e12\u5468\u505c\u7528\u4ed6\u514b\u83ab\u53f8\u548c\u9709\u915a\u9178\u916f\uff1b\u867d\u6709\u4e00\u4f8b\uff08010\uff09\u57286\u4e2a\u6708\u68c0\u6d4b\u5230\u9633\u6027\u6297HLA\u6297\u4f53\uff0c\u4f46\u5e76\u975e\u9488\u5bf9\u4f9b\u4f53\u7279\u5f02\u6027\u6297\u4f53\uff0c\u7814\u7a76\u7ec4\u8ba4\u4e3a\u8fd9\u5e76\u975e\u7531NSC\u79fb\u690d\u76f4\u63a5\u5f15\u8d77\u7684\u514d\u75ab\u6392\u65a5\u53cd\u5e94\u3002<\/p>\n<p><strong>3.\u75bc\u75db\u4e0e\u751f\u6d3b\u8d28\u91cf\uff1a<\/strong>\u75bc\u75db\u65b9\u9762\uff0c001\u548c006\u62a5\u544a\u603b\u4f53\u75bc\u75db\u4e0b\u964d\uff0c008\u75bc\u75db\u52a0\u91cd\u4e14\u56e0\u9ab6\u9aa8\u6e83\u75a1\u572830\u4e2a\u6708\u65f6\u53d1\u751f\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u5bfc\u81f4\u751f\u6d3b\u81ea\u7406\u80fd\u529b\uff08SCIM\uff09\u660e\u663e\u4e0b\u964d\uff0c010\u7684\u75bc\u75db\u548cSCIM\u53d8\u5316\u8f83\u5c0f\uff0c\u603b\u4f533\u540d\u60a3\u8005SCIM\u672a\u89c1\u663e\u8457\u6539\u5584\u3002<\/p>\n<p><strong>4.\u5f71\u50cf\u5b66\u8bc4\u4f30\uff1a<\/strong>\u672f\u540eMRI\u663e\u793a\u6240\u6709\u60a3\u8005\u5b58\u5728\u4e0d\u540c\u7a0b\u5ea6\u7684\u5c40\u7076\u6027\u810a\u9ad3\u8f6f\u5316\uff0c\u4f46\u672a\u89c1\u65b0\u7684\u5e76\u53d1\u5f71\u50cf\u5b66\u5f81\u8c61\uff08\u5982\u6c34\u80bf\u3001\u589e\u5f3a\u6216\u79ef\u6db2\uff09\uff1bDTI\u63d0\u793a\u810a\u9ad3\u675f\u5916\u89c2\u7a33\u5b9a\uff0c\u672a\u89c1\u5e7f\u6cdb\u91cd\u5851\u6216\u7ea4\u7ef4\u675f\u6539\u5584\u3002<\/p>\n<p><strong>5.\u795e\u7ecf\u751f\u7406\u53cd\u5e94\uff1a<\/strong>\u7535\u751f\u7406\u68c0\u67e5\u663e\u793a\u591a\u540d\u60a3\u8005\u5728\u79fb\u690d\u540e\u6570\u6708\u81f3\u6570\u5e74\u95f4\u51fa\u73b0\u65b0\u7684\u808c\u7535\u6d3b\u52a8\u4e0e\u5bf9\u5f3a\u5316\u52a8\u4f5c\u7684\u53cd\u5e94\uff08\u4f8b\u5982001\u3001006\u3001010\u5728\u4e0d\u540c\u8282\u6bb5\u51fa\u73b0\u65b0\u53d1EMG\u4fe1\u53f7\u548c\u589e\u5f3a\u7684\u808c\u8089\u53cd\u5e94\uff09\uff0c\u63d0\u793a\u90e8\u5206\u8282\u6bb5\u51fa\u73b0\u4e86\u529f\u80fd\u6027\u795e\u7ecf\u808c\u8089\u6062\u590d\u8ff9\u8c61\u3002<\/p>\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194718-68d3da469b1da.png\" alt=\"MRI\u9888\u80f8T2\u77e2\u72b6\u56fe\u548cAvDC\u77e2\u72b6\u56fe\" width=\"656\" height=\"291\" title=\"\"><\/figure>\n<p>\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u662f\u4e00\u79cd\u53ef\u884c\u4e14\u76f8\u5bf9\u5b89\u5168\u7684\u65b9\u6cd5\uff0c\u80fd\u591f\u5728\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u4fc3\u8fdb\u6162\u6027\u80f8\u690eSCI\u60a3\u8005\u7684\u795e\u7ecf\u529f\u80fd\u6062\u590d\u3002<\/p>\n<p>2025\u5e747\u67082\u53f7\uff0c\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u795e\u7ecf\u79d1\u5b66\u7cfb\u5728\u56fd\u9645\u6743\u5a01\u671f\u520a\u6742\u5fd7\u300aTranslational Neuroscience\u300b\u53d1\u8868\u4e86\u4e00\u7bc7\u201c\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u201d\u7684\u6587\u732e\u7efc\u8ff0\u3002<sup>[3]<\/sup><\/p>\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194718-68d3da46ac1ba.jpg\" alt=\"\" title=\"\"><\/figure>\n<p>\u8be5\u7efc\u8ff0\u7814\u7a76\u8868\u660e\uff1a<strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u6216\u795e\u7ecf\u7956\u7ec6\u80de (NPC) \u79fb\u690d\u5230\u4e25\u91cd\u810a\u9ad3\u635f\u4f24 (SCI) \u90e8\u4f4d\u540e\u80fd\u591f\u5b58\u6d3b\uff0c\u5206\u5316\u4e3a\u795e\u7ecf\u5143\u548c\u795e\u7ecf\u80f6\u8d28\u7ec6\u80de\uff0c\u5e76\u5ef6\u4f38\u51fa\u5927\u91cf\u8f74\u7a81\uff0c\u5ef6\u4f38\u81f3\u76f8\u5f53\u957f\u7684\u8ddd\u79bb\uff0c\u4ee5\u4fbf\u4e0e\u635f\u4f24\u90e8\u4f4d\u4e0b\u65b9\u7684\u5bbf\u4e3b\u795e\u7ecf\u5143\u5efa\u7acb\u8fde\u63a5<\/strong>\u3002\u53cd\u8fc7\u6765\uff0c\u5bbf\u4e3b\u7684\u8f74\u7a81\u4f1a\u518d\u751f\u5230NSC\/NPC\u79fb\u690d\u7269\u4e2d\uff0c\u5e76\u4e0e\u79fb\u690d\u7269\u6765\u6e90\u7684\u795e\u7ecf\u5143\u5f62\u6210\u7a81\u89e6\u8fde\u63a5\u3002<\/p>\n<p>\u56e0\u6b64\uff0cNSC\/NPC\u79fb\u690d\u7269\u6765\u6e90\u7684\u795e\u7ecf\u5143\u53ef\u4ee5\u4f5c\u4e3a\u795e\u7ecf\u5143\u4e2d\u7ee7\uff0c\u91cd\u5efa\u635f\u4f24\u90e8\u4f4d\u7684\u795e\u7ecf\u4f20\u9012\uff0c\u5373\u4f7f\u5728\u4e25\u91cdSCI\u540e\u4e5f\u80fd\u6539\u5584\u529f\u80fd\u7ed3\u5c40\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"33_%E7%9B%B4%E6%8E%A5%E5%AF%B9%E6%AF%94%E4%B8%8E%E7%BB%BC%E5%90%88%E5%88%86%E6%9E%90\"><\/span>3.3 \u76f4\u63a5\u5bf9\u6bd4\u4e0e\u7efc\u5408\u5206\u6790<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u76ee\u524d\u6781\u5c11\u6709\u5934\u5bf9\u5934\u6bd4\u8f83MSCs\u548cNSCs\u7597\u6548\u7684\u4e34\u5e8a\u7814\u7a76\u3002\u4f46\u4ece\u73b0\u6709\u6570\u636e\u770b\uff1a<\/p>\n<p><strong>\u5b89\u5168\u6027\u200b<\/strong>\u200b\uff1aMSCs\u7684\u4e34\u5e8a\u5b89\u5168\u6027\u8bb0\u5f55\u66f4\u4e3a\u4e30\u5bcc\u548c\u6210\u719f\uff0c\u5e94\u7528\u4e5f\u66f4\u7b80\u4fbf\uff08\u53ef\u9759\u8109\/\u9798\u5185\u7ed9\u836f\uff09\u3002NSCs\u7684\u79fb\u690d\u901a\u5e38\u9700\u8981\u200b\u200b\u7cbe\u51c6\u7684\u75c5\u7076\u5185\u6ce8\u5c04\u200b\u200b\uff0c\u64cd\u4f5c\u66f4\u5177\u4fb5\u5165\u6027\uff0c\u4e14\u5176\u957f\u671f\u5b89\u5168\u6027\uff08\u5982\u81f4\u7624\u6027\uff09\u4ecd\u9700\u66f4\u591a\u6570\u636e\u8bc4\u4f30\u3002<\/p>\n<p><strong>\u6709\u6548\u6027\u200b<\/strong>\u200b\uff1aMSCs\u5728\u200b\u200b\u8c03\u8282\u514d\u75ab\u5fae\u73af\u5883\u3001\u4fdd\u62a4\u6b8b\u5b58\u795e\u7ecf\u7ec4\u7ec7\u200b\u200b\u65b9\u9762\u8868\u73b0\u7a81\u51fa\uff0c\u5c24\u5176\u5728\u6025\u6027\u671f\u548c\u4e9a\u6025\u6027\u671f\u3002\u800cNSCs\u5728\u200b\u200b\u7ed3\u6784\u91cd\u5efa\uff08\u7ec6\u80de\u66ff\u4ee3\uff09\u200b\u200b \u65b9\u9762\u6f5c\u529b\u66f4\u5927\uff0c\u5176\u80fd\u591f\u76f4\u63a5\u66ff\u4ee3\u53d7\u635f\u795e\u7ecf\u5143\uff0c\u91cd\u5efa\u795e\u7ecf\u7f51\u7edc\uff0c\u7a81\u7834\u80f6\u8d28\u7622\u75d5\u7684\u963b\u788d\uff0c\u5bf9\u200b\u200b\u6162\u6027\u671f\u60a3\u8005\u66f4\u6709\u5229\u3002<\/p>\n<p><strong>\u529f\u80fd\u6062\u590d\u6548\u679c\u65b9\u9762<\/strong>\uff1aMSCs\u4e3b\u8981\u6539\u5584ASIA\u8bc4\u5206\u548c\u4f53\u611f\u8bf1\u53d1\u7535\u4f4d\uff0c\u4f46\u5bf9\u67d0\u4e9b\u795e\u7ecf\u529f\u80fd\u5f71\u54cd\u6709\u9650\uff1b\u800cNSCs\u5219\u53ef\u5e26\u6765\u66f4\u5168\u9762\u7684\u611f\u89c9\u4e0e\u8fd0\u52a8\u529f\u80fd\u6539\u5584\uff0c\u5305\u62ec\u7cbe\u7ec6\u8fd0\u52a8\u63a7\u5236\u548c\u6b65\u6001\u534f\u8c03\u6027\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E6%80%BB%E7%BB%93%E4%B8%8E%E5%B1%95%E6%9C%9B%E2%80%8B\"><\/span><strong>\u603b\u7ed3\u4e0e\u5c55\u671b\u200b<\/strong><span 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