{"id":19090,"date":"2025-09-25T03:47:35","date_gmt":"2025-09-24T11:47:35","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/stem-cells\/stem-cell-therapy\/19090.html"},"modified":"2025-10-13T14:45:35","modified_gmt":"2025-10-13T06:45:35","slug":"https-www-hjtdsm-cn-stem-cells-stem-cell-therapy-19090-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19090.html","title":{"rendered":"5 \u0645\u0639\u0627\u064a\u064a\u0631 \u062a\u0642\u064a\u064a\u0645\u064a\u0629 \u0644\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u062a\u0642\u064a\u0624 \u0627\u0644\u0633\u0631\u064a\u0639 \u0627\u0644\u0630\u064a\u0646 \u0647\u0645 \u0627\u0644\u0623\u0646\u0633\u0628 \u0644\u0644\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u062e\u0644\u0627\u064a\u0627 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\u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u062a\u0642\u064a\u0624 \u0627\u0644\u0633\u0631\u064a\u0639 \u0627\u0644\u0630\u064a\u0646 \u0647\u0645 \u0627\u0644\u0623\u0646\u0633\u0628 \u0644\u0644\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19090.html\/#%E4%B8%80%E3%80%81%E8%AE%A4%E8%AF%86%E6%B8%90%E5%86%BB%E7%97%87%E7%9A%84%E5%88%86%E6%9C%9F%E4%B8%8E%E8%AF%84%E4%BC%B0%E5%B7%A5%E5%85%B7\" >\u4e00\u3001\u8ba4\u8bc6\u6e10\u51bb\u75c7\u7684\u5206\u671f\u4e0e\u8bc4\u4f30\u5de5\u5177<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" 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href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19090.html\/#%E4%B8%89%E3%80%81%E9%80%82%E5%BA%94%E8%AF%81%E3%80%81%E7%A6%81%E5%BF%8C%E8%AF%81%E4%B8%8E%E9%9C%80%E7%BB%BC%E5%90%88%E6%9D%83%E8%A1%A1%E7%9A%84%E6%83%85%E5%86%B5\" >\u4e09\u3001\u9002\u5e94\u8bc1\u3001\u7981\u5fcc\u8bc1\u4e0e\u9700\u7efc\u5408\u6743\u8861\u7684\u60c5\u51b5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19090.html\/#%E5%9B%9B%E3%80%81%E6%82%A3%E8%80%85%E5%A6%82%E4%BD%95%E8%BF%9B%E8%A1%8C%E8%87%AA%E6%88%91%E5%88%9D%E6%AD%A5%E5%88%A4%E6%96%AD\" >\u56db\u3001\u60a3\u8005\u5982\u4f55\u8fdb\u884c\u81ea\u6211\u521d\u6b65\u5224\u65ad<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19090.html\/#%E7%BB%93%E8%AF%AD\" 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id=\"%E4%B8%80%E3%80%81%E8%AE%A4%E8%AF%86%E6%B8%90%E5%86%BB%E7%97%87%E7%9A%84%E5%88%86%E6%9C%9F%E4%B8%8E%E8%AF%84%E4%BC%B0%E5%B7%A5%E5%85%B7\"><\/span><strong>\u4e00\u3001\u8ba4\u8bc6\u6e10\u51bb\u75c7\u7684\u5206\u671f\u4e0e\u8bc4\u4f30\u5de5\u5177<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u8bc4\u4f30\u6e10\u51bb\u75c7\u60a3\u8005\u662f\u5426\u9002\u5408\u5e72\u7ec6\u80de\u6cbb\u7597\uff0c\u533b\u751f\u4e3b\u8981\u4f9d\u8d56\u51e0\u4e2a\u5173\u952e\u6307\u6807\uff1a<\/p>\n<ol class=\"wp-block-list\">\n<li>\u200b<strong>\u200bALSFRS-R\u8bc4\u5206\u200b<\/strong>\u200b\uff1a\u8fd9\u662f\u8bc4\u4f30\u60a3\u8005\u65e5\u5e38\u529f\u80fd\uff08\u5982\u8a00\u8bed\u3001\u541e\u54bd\u3001\u884c\u8d70\u3001\u7a7f\u8863\u3001\u547c\u5438\u7b49\uff09\u53d7\u635f\u7a0b\u5ea6\u7684\u91cf\u8868\u3002\u603b\u520648\u5206\uff0c\u200b<strong>\u200b\u5206\u6570\u8d8a\u9ad8\uff0c\u4ee3\u8868\u529f\u80fd\u4fdd\u7559\u8d8a\u597d\u200b<\/strong>\u200b\uff0c\u75c5\u60c5\u76f8\u5bf9\u66f4\u8f7b\u3002<\/li>\n<li>\u200b<strong>\u200b\u80ba\u529f\u80fd\uff08FVC\/%FVC\uff09\u200b<\/strong>\u200b\uff1a\u5373\u7528\u529b\u80ba\u6d3b\u91cf\uff0c\u662f\u8bc4\u4f30\u547c\u5438\u529f\u80fd\u7684\u6838\u5fc3\u6307\u6807\u3002\u901a\u5e38\u8ba4\u4e3a\u200b\u200bFVC \u226570%\u200b\u200b\u662f\u8bb8\u591a\u4e34\u5e8a\u8bd5\u9a8c\u7684\u5165\u7ec4\u6807\u51c6\u4e4b\u4e00\u3002\u5f53FVC\u4f4e\u4e8e50%\u65f6\uff0c\u547c\u5438\u8870\u7aed\u98ce\u9669\u663e\u8457\u589e\u52a0\u3002<\/li>\n<li>\u200b<strong>\u200b\u75c5\u7a0b\u65f6\u957f\u200b<\/strong>\u200b\uff1a\u4ece\u75c7\u72b6\u51fa\u73b0\u5f00\u59cb\u8ba1\u7b97\u7684\u65f6\u95f4\u3002\u4e00\u822c\u6765\u8bf4\uff0c\u200b\u200b\u53d1\u75c5\u65f6\u95f4\u77ed\uff08\u4f8b\u5982&lt;12-18\u4e2a\u6708\uff09\u200b\u200b \u7684\u60a3\u8005\uff0c\u5176\u795e\u7ecf\u5143\u7684\u53ef\u5851\u6027\u548c\u6b8b\u7559\u529f\u80fd\u53ef\u80fd\u66f4\u597d\u3002<\/li>\n<\/ol>\n<p>\u57fa\u4e8e\u8fd9\u4e9b\u6307\u6807\uff0c\u60a3\u8005\u5e38\u88ab\u7c97\u7565\u5206\u4e3a\uff1a<\/p>\n<p>\u200b<strong>\u65e9\u671f\u200b<\/strong>\u200b\uff1a\u901a\u5e38\u6307\u53d1\u75c5\u65f6\u95f4\u8f83\u77ed\uff0830\u5206\uff09\uff0cFVC\u4fdd\u7559\u8f83\u597d\uff08\u226570%\uff09\uff0c\u65e5\u5e38\u751f\u6d3b\u5c1a\u80fd\u81ea\u7406\u3002<\/p>\n<p>\u200b<strong>\u200b\u4e2d\u671f\u200b<\/strong>\u200b\uff1a\u75c7\u72b6\u660e\u663e\u8fdb\u5c55\uff0c\u51fa\u73b0\u591a\u9879\u529f\u80fd\u969c\u788d\uff0cALSFRS-R\u8bc4\u5206\u4e2d\u7b49\uff0c\u53ef\u80fd\u9700\u8981\u8f85\u52a9\u5de5\u5177\uff0c\u4f46\u5c1a\u672a\u5b8c\u5168\u4f9d\u8d56\u547c\u5438\u673a\u3002<\/p>\n<p>\u200b<strong>\u200b\u665a\u671f\u200b<\/strong>\u200b\uff1a\u51fa\u73b0\u4e25\u91cd\u7684\u547c\u5438\u548c\/\u6216\u541e\u54bd\u529f\u80fd\u969c\u788d\uff0cALSFRS-R\u8bc4\u5206\u8f83\u4f4e\uff0c\u901a\u5e38\u9700\u8981\u6c14\u7ba1\u5207\u5f00\u548c\u5b8c\u5168\u4f9d\u8d56\u547c\u5438\u673a\u652f\u6301\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%BA%8C%E3%80%815%E5%A4%A7%E8%AF%84%E4%BC%B0%E6%A0%87%E5%87%86%EF%BC%8C%E5%8A%A9%E4%BD%A0%E7%90%86%E6%80%A7%E9%80%89%E6%8B%A9%E6%B2%BB%E7%96%97%E8%B7%AF%E5%BE%84\"><\/span><strong>\u4e8c\u30015\u5927\u8bc4\u4f30\u6807\u51c6\uff0c\u52a9\u4f60\u7406\u6027\u9009\u62e9\u6cbb\u7597\u8def\u5f84<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_%E7%96%BE%E7%97%85%E9%98%B6%E6%AE%B5%E4%B8%8E%E7%A1%AE%E8%AF%8A%E6%97%B6%E9%97%B4%EF%BC%9A%E6%97%A9%E6%9C%9F%E5%B9%B2%E9%A2%84%E6%98%AF%E5%85%B3%E9%94%AE\"><\/span><strong>1. \u75be\u75c5\u9636\u6bb5\u4e0e\u786e\u8bca\u65f6\u95f4\uff1a\u65e9\u671f\u5e72\u9884\u662f\u5173\u952e<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u75be\u75c5\u53d1\u5c55\u9636\u6bb5\u662f\u8bc4\u4f30\u662f\u5426\u9002\u5408\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u200b\u200b\u9996\u8981\u56e0\u7d20\u200b\u200b\u3002<\/p>\n<p>\u4e34\u5e8a\u7814\u7a76\u548c\u4e13\u5bb6\u89c2\u70b9\u666e\u904d\u8ba4\u4e3a\uff0c\u200b<strong>\u200b\u65e9\u671f\u548c\u4e2d\u671f\u60a3\u8005\u200b\u200b\u5f80\u5f80\u80fd\u4ece\u5e72\u7ec6\u80de\u6cbb\u7597\u4e2d\u83b7\u5f97\u66f4\u591a\u76ca\u5904<\/strong>\u3002\u8fd9\u4e9b\u60a3\u8005\u7684\u795e\u7ecf\u7cfb\u7edf\u5c1a\u672a\u906d\u53d7\u5e7f\u6cdb\u4e0d\u53ef\u9006\u7684\u635f\u4f24\uff0c\u6b8b\u7559\u7684\u5065\u5eb7\u8fd0\u52a8\u795e\u7ecf\u5143\u76f8\u5bf9\u8f83\u591a\uff0c\u4e3a\u5e72\u7ec6\u80de\u53d1\u6325\u4fee\u590d\u3001\u4fdd\u62a4\u548c\u8c03\u8282\u4f5c\u7528\u63d0\u4f9b\u4e86\u66f4\u597d\u7684\u5185\u5728\u73af\u5883\u3002<\/p>\n<p>\u5bf9\u4e8e\u665a\u671f\u60a3\u8005\uff0c\u56e0\u795e\u7ecf\u7cfb\u7edf\u5df2\u5e7f\u6cdb\u53d7\u635f\u3001\u6b8b\u5b58\u795e\u7ecf\u5143\u5be5\u5be5\u65e0\u51e0\uff0c\u4e14\u6574\u4f53\u8eab\u4f53\u72b6\u51b5\u8f83\u5dee\uff0c\u5e72\u7ec6\u80de\u7597\u6cd5\u96be\u4ee5\u9006\u8f6c\u4e25\u91cd\u635f\u4f24\uff1b\u540c\u65f6\u624b\u672f\u6216\u76f8\u5173\u514d\u75ab\u5e72\u9884\u5e26\u6765\u7684\u98ce\u9669\u53ef\u80fd\u8d85\u8fc7\u6f5c\u5728\u6536\u76ca\uff0c<strong>\u56e0\u6b64\u901a\u5e38\u4e0d\u5b9c\u5c06\u665a\u671f\u60a3\u8005\u4f5c\u4e3a\u9996\u9009\u9002\u5e94\u4eba\u7fa4\uff0c\u6cbb\u7597\u9884\u671f\u4e5f\u76f8\u5bf9\u6709\u9650\u3002<\/strong><\/p>\n<h3><span class=\"ez-toc-section\" id=\"2%E8%BA%AB%E4%BD%93%E5%8A%9F%E8%83%BD%E7%8A%B6%E6%80%81%EF%BC%9A%E5%85%B3%E9%94%AE%E8%AF%84%E5%88%86%E4%B8%8E%E8%82%BA%E5%8A%9F%E8%83%BD%E6%8C%87%E6%A0%87\"><\/span><strong>2.\u8eab\u4f53\u529f\u80fd\u72b6\u6001\uff1a\u5173\u952e\u8bc4\u5206\u4e0e\u80ba\u529f\u80fd\u6307\u6807<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u533b\u7597\u56e2\u961f\u4f1a\u901a\u8fc7\u4e00\u7cfb\u5217\u6807\u51c6\u5316\u91cf\u8868\u548c\u6570\u636e\u6765\u5ba2\u89c2\u8bc4\u4f30\u60a3\u8005\u7684\u8eab\u4f53\u529f\u80fd\u72b6\u6001\uff0c\u8fd9\u662f\u5224\u65ad\u662f\u5426\u9002\u5408\u6cbb\u7597\u7684\u91cd\u8981\u4f9d\u636e\u3002<\/p>\n<p>\u200b<strong>\u200bALSFRS-R\u8bc4\u5206\u200b<\/strong>\u200b\uff1a\u8fd9\u662f\u8bc4\u4f30\u60a3\u8005\u65e5\u5e38\u529f\u80fd\uff08\u5982\u8a00\u8bed\u3001\u541e\u54bd\u3001\u884c\u8d70\u3001\u7a7f\u8863\u3001\u547c\u5438\u7b49\uff09\u53d7\u635f\u7a0b\u5ea6\u7684\u91cf\u8868\u3002\u603b\u520648\u5206\uff0c\u200b\u200b\u5206\u6570\u8d8a\u9ad8\uff0c\u4ee3\u8868\u529f\u80fd\u4fdd\u7559\u8d8a\u597d\u200b\u200b\u3002\u901a\u5e38\u8ba4\u4e3a\u8bc4\u5206\u8f83\u9ad8\u7684\u60a3\u8005\u662f\u66f4\u5408\u9002\u7684\u5019\u9009\u8005\u3002<\/p>\n<p>\u200b<strong>\u200b\u80ba\u529f\u80fd\uff08FVC\/%FVC\uff09\u200b<\/strong>\u200b\uff1a\u5373\u7528\u529b\u80ba\u6d3b\u91cf\uff0c\u662f\u8bc4\u4f30\u547c\u5438\u529f\u80fd\u7684\u6838\u5fc3\u6307\u6807\u3002\u8bb8\u591a\u4e34\u5e8a\u8bd5\u9a8c\u8981\u6c42\u60a3\u8005\u7684\u200b\u200bFVC\u226550%\u200b\u200b\u624d\u80fd\u5165\u7ec4\u3002\u5f53FVC\u4f4e\u4e8e50%\u65f6\uff0c\u547c\u5438\u8870\u7aed\u98ce\u9669\u663e\u8457\u589e\u52a0\uff0c\u6cbb\u7597\u98ce\u9669\u4e5f\u76f8\u5e94\u589e\u5927\u3002<\/p>\n<p>\u4e0b\u8868\u6982\u8ff0\u4e86\u4e0d\u540c\u8eab\u4f53\u529f\u80fd\u72b6\u6001\u60a3\u8005\u7684\u4e00\u822c\u9002\u7528\u60c5\u51b5\uff1a<\/p>\n<figure class=\"wp-block-table is-style-stripes\">\n<table class=\"has-fixed-layout\">\n<thead>\n<tr>\n<th>\u200b<strong>\u200b\u529f\u80fd\u72b6\u6001\u200b<\/strong>\u200b<\/th>\n<th>\u200b<strong>\u200bALSFRS-R\u8bc4\u5206\u200b<\/strong>\u200b<\/th>\n<th>\u200b<strong>\u200b\u80ba\u529f\u80fdFVC\u200b<\/strong>\u200b<\/th>\n<th>\u200b<strong>\u200b\u662f\u5426\u9002\u5408\u6cbb\u7597\u200b<\/strong>\u200b<\/th>\n<th>\u200b<strong>\u200b\u8bf4\u660e\u200b<\/strong>\u200b<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u200b<strong>\u200b\u529f\u80fd\u8f83\u597d\u200b<\/strong>\u200b<\/td>\n<td>&gt;30\u5206<\/td>\n<td>\u226570%<\/td>\n<td>\u2705 \u66f4\u9002\u5408<\/td>\n<td>\u8eab\u4f53\u529f\u80fd\u4fdd\u7559\u8f83\u597d\uff0c\u6cbb\u7597\u6f5c\u5728\u83b7\u76ca\u53ef\u80fd\u66f4\u5927\uff0c\u98ce\u9669\u76f8\u5bf9\u8f83\u4f4e\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u200b<strong>\u200b\u529f\u80fd\u4e2d\u5ea6\u53d7\u635f\u200b<\/strong>\u200b<\/td>\n<td>20-30\u5206<\/td>\n<td>50%-70%<\/td>\n<td>\u26a0\ufe0f \u8c28\u614e\u8bc4\u4f30<\/td>\n<td>\u9700\u7531\u533b\u751f\u7efc\u5408\u8bc4\u4f30\u9884\u671f\u83b7\u76ca\u4e0e\u6f5c\u5728\u98ce\u9669\uff0c\u5171\u540c\u51b3\u7b56\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u200b<strong>\u200b\u529f\u80fd\u4e25\u91cd\u53d7\u635f\u200b<\/strong>\u200b<\/td>\n<td>&lt;20\u5206<\/td>\n<td>&lt;50%<\/td>\n<td>\u274c \u901a\u5e38\u4e0d\u9002\u5408<\/td>\n<td>\u6cbb\u7597\u96be\u4ee5\u9006\u8f6c\u4e25\u91cd\u635f\u4f24\uff0c\u98ce\u9669\u53ef\u80fd\u5927\u4e8e\u83b7\u76ca\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<h3><span class=\"ez-toc-section\" id=\"3%E5%B9%B4%E9%BE%84%E4%B8%8E%E6%95%B4%E4%BD%93%E5%81%A5%E5%BA%B7%E7%8A%B6%E5%86%B5%EF%BC%9A%E5%AE%89%E5%85%A8%E6%80%A7%E7%9A%84%E4%BF%9D%E9%9A%9C\"><\/span><strong>3.\u5e74\u9f84\u4e0e\u6574\u4f53\u5065\u5eb7\u72b6\u51b5\uff1a\u5b89\u5168\u6027\u7684\u4fdd\u969c<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u5e72\u7ec6\u80de\u6cbb\u7597\u672c\u8eab\u5177\u6709\u4e00\u5b9a\u7684\u4fb5\u5165\u6027\uff08\u5982\u9798\u5185\u6ce8\u5c04\uff09\uff0c\u56e0\u6b64\u9700\u8981\u60a3\u8005\u6709\u76f8\u5bf9\u826f\u597d\u7684\u6574\u4f53\u5065\u5eb7\u72b6\u51b5\u6765\u8010\u53d7\u6cbb\u7597\u8fc7\u7a0b\u548c\u53ef\u80fd\u7684\u526f\u4f5c\u7528\u3002<\/p>\n<p>\u200b<strong>\u200b\u5e74\u9f84\u8303\u56f4\u200b<\/strong>\u200b\uff1a\u8bb8\u591a\u4e34\u5e8a\u8bd5\u9a8c\u4f1a\u5c06\u60a3\u8005\u7684\u5e74\u9f84\u9650\u5236\u5728\u200b\u200b18-75\u5c81\u4e4b\u95f4\u200b\u200b\u3002<\/p>\n<p>\u200b<strong>\u200b\u91cd\u8981\u5668\u5b98\u529f\u80fd\u200b<\/strong>\u200b\uff1a\u60a3\u8005\u4e0d\u5e94\u6709\u200b\u200b\u4e25\u91cd\u7684\u5fc3\u3001\u809d\u3001\u80be\u529f\u80fd\u4e0d\u5168\u200b\u200b\uff0c\u8fd9\u4e9b\u72b6\u51b5\u901a\u5e38\u662f\u6cbb\u7597\u7684\u660e\u786e\u7981\u5fcc\u8bc1\u3002<\/p>\n<p>\u200b<strong>\u200b\u514d\u75ab\u4e0e\u611f\u67d3\u72b6\u6001\u200b<\/strong>\u200b\uff1a\u5b58\u5728\u200b\u200b\u6d3b\u52a8\u6027\u3001\u672a\u63a7\u5236\u7684\u611f\u67d3\u200b\u200b\u6216\u200b\u200b\u51dd\u8840\u529f\u80fd\u4e25\u91cd\u5f02\u5e38\u200b\u200b\u7684\u60a3\u8005\uff0c\u901a\u5e38\u4e0d\u9002\u5408\u63a5\u53d7\u6cbb\u7597\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"4%E5%BF%83%E7%90%86%E9%A2%84%E6%9C%9F%E4%B8%8E%E5%AE%B6%E5%BA%AD%E6%94%AF%E6%8C%81%EF%BC%9A%E7%90%86%E6%80%A7%E7%9C%8B%E5%BE%85%E7%96%97%E6%95%88\"><\/span><strong>4.\u5fc3\u7406\u9884\u671f\u4e0e\u5bb6\u5ead\u652f\u6301\uff1a\u7406\u6027\u770b\u5f85\u7597\u6548<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u60a3\u8005\u548c\u5bb6\u5c5e\u5bf9\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u200b\u200b\u9884\u671f\u5fc5\u987b\u79d1\u5b66\u4e14\u7406\u6027\u200b\u200b\u3002\u76ee\u524d\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u4e3b\u8981\u7528\u4e8e\u200b<strong>\u200b\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\u3001\u6539\u5584\u751f\u6d3b\u8d28\u91cf\u200b<\/strong>\u200b\uff0c\u800c\u975e\u5f7b\u5e95\u6cbb\u6108\u6e10\u51bb\u75c7\u3002<\/p>\n<p>\u200b\u200b\u826f\u597d\u7684\u5bb6\u5ead\u652f\u6301\u7cfb\u7edf\u200b\u200b\u5bf9\u4e8e\u60a3\u8005\u672f\u540e\u5eb7\u590d\u3001\u5e94\u5bf9\u53ef\u80fd\u7684\u60c5\u7eea\u6ce2\u52a8\u4ee5\u53ca\u575a\u6301\u957f\u671f\u968f\u8bbf\u81f3\u5173\u91cd\u8981\u3002\u540c\u65f6\uff0c\u60a3\u8005\u60c5\u7eea\u7a33\u5b9a\u3001\u80fd\u79ef\u6781\u914d\u5408\u533b\u7597\u65b9\u6848\u4e5f\u662f\u8003\u91cf\u7684\u56e0\u7d20\u4e4b\u4e00\u3002\u7814\u7a76\u8868\u660e\uff0c\u5e72\u7ec6\u80de\u79fb\u690d\u540e\u6709\u52a9\u7f13\u89e3\u60a3\u8005\u7684\u7126\u8651\u3001\u6291\u90c1\u60c5\u7eea\uff0c\u6539\u5584\u7761\u7720\u8d28\u91cf\uff0c\u8fd9\u5bf9\u6cbb\u7597\u4e5f\u662f\u6709\u76ca\u7684\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"5%E6%97%A2%E5%BE%80%E6%B2%BB%E7%96%97%E5%8F%B2%E4%B8%8E%E5%9F%BA%E5%9B%A0%E8%83%8C%E6%99%AF\"><\/span><strong>5.\u65e2\u5f80\u6cbb\u7597\u53f2\u4e0e\u57fa\u56e0\u80cc\u666f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u65e2\u5f80\u7528\u836f\u3001\u53c2\u52a0\u8fc7\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3001\u5eb7\u590d\u6cbb\u7597\u53f2\u4ee5\u53ca\u662f\u5426\u5b58\u5728\u81f4\u75c5\u57fa\u56e0\u53d8\u5f02\uff0c\u90fd\u4f1a\u5f71\u54cd\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u9009\u62e9\u3001\u7597\u6548\u5224\u65ad\u4e0e\u5b89\u5168\u76d1\u6d4b\u3002<\/p>\n<p><strong>\u65e2\u5f80\/\u73b0\u7528\u836f\u7269<\/strong>\uff1a\u4f8b\u5982\u5229\u9c81\u5511\u3001\u4f9d\u8fbe\u62c9\u5949\u3001\u6216\u6b63\u5728\u63a5\u53d7\u5176\u4ed6\u514d\u75ab\/\u9776\u5411\u6cbb\u7597\uff0c\u9700\u8bc4\u4f30\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u4e0e\u505c\u7528\u7a97\u53e3\uff1b\u67d0\u4e9b\u836f\u7269\u53ef\u80fd\u5f71\u54cd\u708e\u75c7\u72b6\u6001\u4e0e\u7ec6\u80de\u7597\u6cd5\u7684\u6548\u679c\u3002<\/p>\n<p><strong>\u5eb7\u590d\u4e0e\u8425\u517b\u5e72\u9884\u53f2<\/strong>\uff1a\u6301\u7eed\u7684\u5eb7\u590d\u8bad\u7ec3\u3001\u8425\u517b\u652f\u6301\u80fd\u653e\u5927\u5e72\u7ec6\u80de\u6cbb\u7597\u5e26\u6765\u7684\u529f\u80fd\u6539\u5584\uff0c\u4e14\u662f\u7efc\u5408\u7ba1\u7406\u7684\u91cd\u8981\u7ec4\u6210\u90e8\u5206\u3002<\/p>\n<p><strong>\u65e2\u5f80\u53c2\u4e0e\u4e34\u5e8a\u8bd5\u9a8c<\/strong>\uff1a\u82e5\u66fe\u63a5\u53d7\u8fc7\u5176\u4ed6\u7ec6\u80de\u6216\u57fa\u56e0\u7597\u6cd5\uff0c\u9700\u8981\u63d0\u4f9b\u8be6\u7ec6\u8d44\u6599\uff08\u8bd5\u9a8c\u7f16\u53f7\u3001\u7528\u836f\u65b9\u6848\u3001\u968f\u8bbf\u7ed3\u679c\uff09\uff0c\u4ee5\u4fbf\u8bc4\u4f30\u91cd\u590d\u7528\u836f\u7684\u5b89\u5168\u6027\u4e0e\u514d\u75ab\u5b66\u5f71\u54cd\u3002<\/p>\n<p><strong>\u57fa\u56e0\u80cc\u666f<\/strong>\uff1a\u5b58\u5728 SOD1\u3001C9orf72\u3001FUS \u7b49\u81f4\u75c5\u6216\u9ad8\u98ce\u9669\u53d8\u5f02\u7684\u60a3\u8005\uff0c\u75c5\u7406\u673a\u5236\u4e0e\u75be\u75c5\u8fdb\u5c55\u4e0d\u540c\uff0c\u90e8\u5206\u57fa\u56e0\u578b\u7684\u60a3\u8005\u5728\u7279\u5b9a\u7597\u6cd5\uff08\u5982\u57fa\u4e8e\u57fa\u56e0\u7684\u9776\u5411\u6cbb\u7597\uff09\u4e2d\u53ef\u80fd\u5177\u6709\u66f4\u660e\u786e\u7684\u6cbb\u7597\u7b56\u7565\u6216\u7981\u5fcc\u3002\u57fa\u56e0\u9633\u6027\u7684\u60a3\u8005\u9700\u4e0e\u9057\u4f20\u54a8\u8be2\u7ed3\u5408\u8bc4\u4f30\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u98ce\u9669\u2014\u6709\u65f6\u9700\u8981\u66f4\u8c28\u614e\u6216\u4f18\u5148\u8003\u8651\u7279\u5f02\u6027\u9776\u5411\u6cbb\u7597\u7814\u7a76\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%B8%89%E3%80%81%E9%80%82%E5%BA%94%E8%AF%81%E3%80%81%E7%A6%81%E5%BF%8C%E8%AF%81%E4%B8%8E%E9%9C%80%E7%BB%BC%E5%90%88%E6%9D%83%E8%A1%A1%E7%9A%84%E6%83%85%E5%86%B5\"><\/span><strong>\u4e09\u3001\u9002\u5e94\u8bc1\u3001\u7981\u5fcc\u8bc1\u4e0e\u9700\u7efc\u5408\u6743\u8861\u7684\u60c5\u51b5<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5b89\u5168\u6027\u662f\u533b\u7597\u51b3\u7b56\u7684\u9996\u8981\u8003\u8651\u56e0\u7d20\u3002\u5b89\u5168\u6c38\u8fdc\u662f\u7b2c\u4e00\u4f4d\u7684\u3002\u67d0\u4e9b\u7981\u5fcc\u75c7\u4f1a\u76f4\u63a5\u589e\u52a0\u624b\u672f\u98ce\u9669\uff0c\u6216\u4f7f\u5f97\u5e72\u7ec6\u80de\u96be\u4ee5\u5b58\u6d3b\u548c\u53d1\u6325\u4f5c\u7528\u3002\u53e6\u4e00\u4e9b\u60c5\u51b5\u5219\u53ef\u80fd\u8ba9\u60a3\u8005\u65e0\u6cd5\u914d\u5408\u957f\u671f\u7684\u968f\u8bbf\u8bc4\u4f30\uff0c\u5bfc\u81f4\u65e0\u6cd5\u5224\u65ad\u771f\u5b9e\u7597\u6548\u3002<\/p>\n<p>\u4ee5\u4e0b\u60c5\u51b5\u7684\u60a3\u8005\u200b\u200b\u4e0d\u9002\u5408\u200b\u200b\u63a5\u53d7\u5e72\u7ec6\u80de\u6cbb\u7597\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li>\u6d3b\u52a8\u6027\u764c\u75c7\u200b\u200b\u6216\u200b\u200b\u8fd1\u671f\u6709\u764c\u75c7\u53f2\u200b\u200b\u3002<\/li>\n<li>\u4e25\u91cd\u4e14\u672a\u63a7\u5236\u7684\u7cfb\u7edf\u6027\u75be\u75c5\u3002<\/li>\n<li>\u6d3b\u52a8\u6027\u611f\u67d3\u200b\u200b\u3002<\/li>\n<li>\u200b\u200b\u4e25\u91cd\u51dd\u8840\u529f\u80fd\u969c\u788d\u200b\u200b\u6216\u6b63\u5728\u4f7f\u7528\u6297\u51dd\u836f\u7269\uff0c\u589e\u52a0\u9885\u5185\u51fa\u8840\u98ce\u9669\u3002<\/li>\n<li>\u200b\u200b\u5b58\u5728\u690d\u5165\u624b\u672f\u7684\u5c40\u90e8\u7981\u5fcc\u200b\u200b\u3002<\/li>\n<li>\u200b\u200b\u60a3\u6709\u4e25\u91cd\u4e0d\u53ef\u63a7\u7684\u7cbe\u795e\u75be\u75c5\u200b\u200b\u200b\u200b\uff0c\u65e0\u6cd5\u914d\u5408\u6cbb\u7597\u548c\u968f\u8bbf\u3002<\/li>\n<li>\u6b63\u5728\u53c2\u4e0e\u5176\u4ed6\u5e72\u9884\u6027\u4e34\u5e8a\u8bd5\u9a8c<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%E5%9B%9B%E3%80%81%E6%82%A3%E8%80%85%E5%A6%82%E4%BD%95%E8%BF%9B%E8%A1%8C%E8%87%AA%E6%88%91%E5%88%9D%E6%AD%A5%E5%88%A4%E6%96%AD\"><\/span><strong>\u56db\u3001\u60a3\u8005\u5982\u4f55\u8fdb\u884c\u81ea\u6211\u521d\u6b65\u5224\u65ad<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5982\u679c\u60a8\u6216\u5bb6\u4eba\u5bf9<span class=\"xintheme_tag_link\">\u5e72\u7ec6\u80de\u6cbb\u7597\u6e10\u51bb\u75c7<\/span>\u611f\u5174\u8da3\uff0c\u53ef\u4ee5\u53c2\u8003\u4ee5\u4e0b\u51e0\u4e2a\u6b65\u9aa4\uff0c\u5148\u8fdb\u884c\u81ea\u6211\u521d\u6b65\u5224\u65ad\uff0c\u518d\u51b3\u5b9a\u662f\u5426\u8fdb\u4e00\u6b65\u54a8\u8be2\u533b\u751f\uff1a<\/p>\n<p><strong>1. \u4e86\u89e3\u81ea\u8eab\u75c5\u7a0b<\/strong>\uff1a\u67e5\u9605\u75c5\u5386\u6216\u95e8\u8bca\u8bb0\u5f55\uff0c\u660e\u786e\u9996\u6b21\u53d1\u75c5\u65f6\u95f4\u3001\u786e\u8bca\u65f6\u95f4\u4ee5\u53ca\u76ee\u524d\u6240\u5904\u7684\u75be\u75c5\u9636\u6bb5\u3002\u4e00\u822c\u6765\u8bf4\uff0c\u75c5\u7a0b\u5728 1\u20132\u5e74\u4ee5\u5185\u3001\u529f\u80fd\u72b6\u6001\u5c1a\u53ef\u7684\u60a3\u8005\uff0c\u66f4\u6709\u53ef\u80fd\u6210\u4e3a\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u6f5c\u5728\u9002\u5408\u4eba\u7fa4\u3002<\/p>\n<p><strong>2. \u8bc4\u4f30\u529f\u80fd\u72b6\u51b5<\/strong>\uff1a\u5173\u6ce8\u65e5\u5e38\u751f\u6d3b\u80fd\u529b\u548c\u547c\u5438\u529f\u80fd\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>ALSFRS-R\u8bc4\u5206<\/strong>\uff08\u529f\u80fd\u91cf\u8868\uff09\uff1a\u8d8a\u9ad8\u8bf4\u660e\u529f\u80fd\u4fdd\u7559\u8d8a\u597d\uff1b<\/li>\n<li><strong>\u80ba\u529f\u80fd\uff08%FVC\uff09<\/strong>\uff1a\u6700\u597d\u226550%\uff0c\u226570% \u66f4\u4f73\uff1b<\/li>\n<li>\u4e3b\u8981\u969c\u788d\u5982\u8fd0\u52a8\uff08\u884c\u8d70\u56f0\u96be\u3001\u62ac\u624b\u53d7\u9650\uff09\u3001\u8a00\u8bed\uff08\u6784\u97f3\u4e0d\u6e05\uff09\u3001\u541e\u54bd\u6216\u547c\u5438\u7b49\u60c5\u51b5\uff0c\u90fd\u53ef\u4f5c\u4e3a\u5224\u65ad\u7684\u91cd\u8981\u53c2\u8003\u3002<\/li>\n<\/ul>\n<p><strong>3. \u54a8\u8be2\u4e3b\u6cbb\u533b\u751f<\/strong>\uff1a\u5c06\u75c5\u7a0b\u3001\u529f\u80fd\u72b6\u6001\u3001\u547c\u5438\u60c5\u51b5\u7b49\u5982\u5b9e\u544a\u77e5\u795e\u7ecf\u5185\u79d1\u6216\u5eb7\u590d\u79d1\u533b\u751f\uff0c\u7531\u4e13\u4e1a\u533b\u751f\u7efc\u5408\u8bc4\u4f30\u6cbb\u7597\u53ef\u884c\u6027\u3001\u6f5c\u5728\u98ce\u9669\u4ee5\u53ca\u662f\u5426\u5b58\u5728\u7981\u5fcc\u75c7\u3002<\/p>\n<p><strong>4. \u5bfb\u627e\u6b63\u89c4\u673a\u6784<\/strong>\uff1a\u4f18\u5148\u9009\u62e9\u5f00\u5c55\u6ce8\u518c\u4e34\u5e8a\u8bd5\u9a8c\u6216\u62e5\u6709\u5e72\u7ec6\u80de\u4e34\u5e8a\u7814\u7a76\u5907\u6848\u7684\u533b\u9662\/\u7ec6\u80de\u673a\u6784\uff0c\u6838\u5b9e\u662f\u5426\u5177\u5907\u4f26\u7406\u5ba1\u6279\u548c GMP\u5b9e\u9a8c\u5ba4\u3002\u907f\u514d\u8f7b\u4fe1\u5546\u4e1a\u5e7f\u544a\u6216\u201c\u5730\u4e0b\u8bca\u6240\u201d\u7684\u865a\u5047\u5ba3\u4f20\u3002<\/p>\n<p><strong>5. \u505a\u597d\u8eab\u5fc3\u51c6\u5907<\/strong>\uff1a\u63d0\u524d\u4e0e\u5bb6\u4eba\u6c9f\u901a\u597d\u7ecf\u6d4e\u6210\u672c\u3001\u7167\u62a4\u4e0e\u5eb7\u590d\u8ba1\u5212\uff0c\u786e\u4fdd\u6709\u826f\u597d\u7684\u5fc3\u7406\u652f\u6301\u548c\u5bb6\u5ead\u966a\u4f34\uff0c\u624d\u80fd\u6700\u5927\u5316\u6cbb\u7597\u914d\u5408\u5ea6\u548c\u83b7\u76ca\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E7%BB%93%E8%AF%AD\"><\/span><strong>\u7ed3\u8bed<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5e72\u7ec6\u80de\u6cbb\u7597\u4e3a\u6e10\u51bb\u75c7\u60a3\u8005\u5e26\u6765\u4e86\u65b0\u7684\u9009\u62e9\u548c\u5e0c\u671b\uff0c\u4f46\u5b83\u662f\u4e00\u628a\u9700\u8981\u8c28\u614e\u4f7f\u7528\u7684\u201c\u94a5\u5319\u201d\u3002\u786e\u8bca\u65f6\u95f4\u65e9\u3001\u547c\u5438\u529f\u80fd\u8f83\u597d\u3001\u5e74\u9f84\u76f8\u5bf9\u8f83\u8f7b\u3001\u65e0\u4e25\u91cd\u5408\u5e76\u75c7\u3001\u4e14\u80fd\u7406\u6027\u770b\u5f85\u7597\u6548\u7684\u60a3\u8005\uff0c\u66f4\u6709\u53ef\u80fd\u4ece\u4e2d\u83b7\u76ca\u3002<\/p>\n<p>\u51b3\u5b9a\u662f\u5426\u5c1d\u8bd5\u5e72\u7ec6\u80de\u6cbb\u7597\uff0c\u662f\u4e00\u4e2a\u9700\u8981\u4e0e\u60a8\u7684\u4e3b\u6cbb\u795e\u7ecf\u79d1\u533b\u751f\u6df1\u5165\u6c9f\u901a\u3001\u5168\u9762\u8bc4\u4f30\u540e\u4f5c\u51fa\u7684\u533b\u7597\u51b3\u7b56\u3002\u5207\u8bb0\uff0c\u6700\u5927\u7684\u98ce\u9669\u6765\u81ea\u4e8e\u5bf9\u98ce\u9669\u7684\u672a\u77e5\u548c\u5ffd\u89c6\u3002\u5728\u8ffd\u6c42\u5e0c\u671b\u7684\u8def\u4e0a\uff0c\u79d1\u5b66\u548c\u7406\u6027\u6c38\u8fdc\u662f\u60a8\u6700\u53ef\u9760\u7684\u706f\u5854<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow 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