{"id":19187,"date":"2025-09-25T04:01:25","date_gmt":"2025-09-24T12:01:25","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/stem-cells\/stem-cell-therapy\/19187.html"},"modified":"2025-10-11T14:51:48","modified_gmt":"2025-10-11T06:51:48","slug":"https-www-hjtdsm-cn-stem-cells-stem-cell-therapy-19187-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19187.html","title":{"rendered":"\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0644\u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646: \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0644\u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646: \u0627\u0644\u0645\u0631\u062d\u0644\u0629 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size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924200121-68d3dd9196c86.jpg\" alt=\"\" width=\"612\" height=\"408\" title=\"\"><\/figure>\n<p>\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u7684\u9759\u8109\u8f93\u6ce8\u9010\u6e10\u6210\u4e3a\u4e00\u79cd\u66f4\u5177\u524d\u666f\u4e14\u5b89\u5168\u7684\u6cbb\u7597\u9009\u62e9\u3002<strong>\u8fd9\u7c7b\u7ec6\u80de\u56e0\u5176\u5f3a\u5927\u7684\u514d\u75ab\u8c03\u8282\u529f\u80fd\u800c\u53d7\u5230\u5173\u6ce8\uff0c\u80fd\u591f\u901a\u8fc7\u8c03\u8282\u5916\u5468\u514d\u75ab\u7cfb\u7edf\u6765\u6539\u5584PD\u7684\u6838\u5fc3\u75c5\u7406\u73af\u8282\u2014\u2014\u795e\u7ecf\u708e\u75c7<\/strong>\u3002\u6b64\u5916\uff0cMSCs\u8fd8\u5177\u6709\u514d\u75ab\u539f\u6027\u4f4e\u3001\u81f4\u7624\u98ce\u9669\u5c0f\u3001\u6613\u4e8e\u4ece\u591a\u79cd\u7ec4\u7ec7\u4e2d\u83b7\u53d6\u5e76\u5b9e\u73b0\u89c4\u6a21\u5316\u751f\u4ea7\u3001\u4f26\u7406\u4e89\u8bae\u8f83\u5c11\u7b49\u7efc\u5408\u4f18\u52bf\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E5%B8%95%E9%87%91%E6%A3%AE%E7%97%85%E7%9A%84%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6%EF%BC%9A%E7%B3%BB%E7%BB%9F%E6%80%A7%E5%85%8D%E7%96%AB%E8%B0%83%E8%8A%82%E4%B8%8E%E7%A5%9E%E7%BB%8F%E8%90%A5%E5%85%BB%E6%94%AF%E6%8C%81\"><\/span><strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u4f5c\u7528\u673a\u5236\uff1a\u7cfb\u7edf\u6027\u514d\u75ab\u8c03\u8282\u4e0e\u795e\u7ecf\u8425\u517b\u652f\u6301<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5728PD\u52a8\u7269\u6a21\u578b\u4e2d\uff0c<strong>MSCs\u88ab\u8bc1\u660e\u53ef\u901a\u8fc7\u591a\u9776\u70b9\u673a\u5236\u51cf\u5c11\u5c0f\u80f6\u8d28\u7ec6\u80de\u6d3b\u5316\uff0c\u5e76\u4fc3\u8fdb\u591a\u5df4\u80fa\u795e\u7ecf\u5143\u5b58\u6d3b<\/strong>\u3002\u867d\u7136\u6709\u7814\u7a76\u8868\u660e\uff0cMSCs\u53ef\u80fd\u8fc1\u79fb\u81f3\u9ed1\u8d28\u5e76\u901a\u8fc7\u4e0e\u591a\u5df4\u80fa\u80fd\u7ec6\u80de\u76f4\u63a5\u76f8\u4e92\u4f5c\u7528\u6291\u5236\u5c0f\u80f6\u8d28\u7ec6\u80de\u6d3b\u5316\uff0c\u4f46\u7531\u4e8e\u5176\u76f4\u5f84\uff0815\u201330\u03bcm\uff09\u8f83\u5927\uff0c\u7ea680%\u201390%\u4f1a\u88ab\u56f0\u5728\u80ba\u90e8\u72ed\u7a84\u7684\u6bdb\u7ec6\u8840\u7ba1\u4e2d\uff0c\u56e0\u800c\u76f4\u63a5\u690d\u5165\u6781\u4e3a\u7f55\u89c1\u4e14\u77ed\u6682\u3002<\/p>\n<p>\u5176\u6838\u5fc3\u4f5c\u7528\u673a\u5236\u5728\u4e8e<strong>\u7cfb\u7edf\u6027\u514d\u75ab\u8c03\u8282\u548c\u795e\u7ecf\u8425\u517b\u652f\u6301<\/strong>\u3002\u76ee\u524d\u8ba4\u4e3a\uff0cMSCs\u6216\u5176\u5206\u6ccc\u4f53\uff08\u5982\u7ec6\u80de\u5916\u56ca\u6ce1\u548c\u5916\u6ccc\u4f53\uff09\u4f5c\u4e3a\u201c\u5fae\u5de5\u5382\u201d\u53d1\u6325\u4f5c\u7528\uff0c\u901a\u8fc7\u91ca\u653e\u6297\u708e\u7ec6\u80de\u56e0\u5b50\uff08\u5982TGF-\u03b2\u3001IL-10\u3001PGE2\uff09\u6765\u8c03\u8282\u5168\u8eab\u514d\u75ab\u53cd\u5e94\uff0c\u5e76\u53ef\u80fd\u964d\u4f4e\u8840\u8111\u5c4f\u969c\u7684\u901a\u900f\u6027\u3002<\/p>\n<p>\u540c\u65f6\uff0c\u5b83\u4eec\u8fd8\u80fd\u5206\u6ccc\u591a\u79cd\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff08\u5982BDNF\u3001GDNF\u3001NGF\uff09\uff0c\u4ece\u800c\u4fc3\u8fdb\u795e\u7ecf\u5143\u5b58\u6d3b\u3001\u4fee\u590d\u4e0e\u7a81\u89e6\u53ef\u5851\u6027\u3002\u5728PD\u52a8\u7269\u6a21\u578b\u4e2d\uff0cMSCs\u88ab\u8bc1\u5b9e\u53ef\u901a\u8fc7\u8fd9\u4e9b\u591a\u9776\u70b9\u673a\u5236\u6291\u5236\u5c0f\u80f6\u8d28\u7ec6\u80de\u6d3b\u5316\uff0c\u5e76\u652f\u6301\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u5b58\u6d3b\uff0c\u4ece\u800c\u6709\u671b\u5e72\u9884\u75be\u75c5\u7684\u75c5\u7406\u8fdb\u7a0b\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%BB%8E%E7%90%86%E8%AE%BA%E5%88%B0%E5%AE%9E%E8%B7%B5%EF%BC%9AI%E6%9C%9F%E4%B8%B4%E5%BA%8A%E7%A0%94%E7%A9%B6%E5%90%AF%E7%A4%BA%E4%B8%8EII%E6%9C%9F%E8%AF%95%E9%AA%8C%E8%AE%BE%E8%AE%A1\"><\/span><strong>\u4ece\u7406\u8bba\u5230\u5b9e\u8df5\uff1aI\u671f\u4e34\u5e8a\u7814\u7a76\u542f\u793a\u4e0eII\u671f\u8bd5\u9a8c\u8bbe\u8ba1<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u57fa\u4e8e\u4e0a\u8ff0\u7406\u8bba\uff0c<a href=\"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.28582\" target=\"_blank\" rel=\"nofollow noopener\">\u7f8e\u56fd\u5fb7\u514b\u8428\u65af\u5927\u5b66\u9ea6\u6208\u6587\u533b\u5b66\u9662<\/a>\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u6211\u4eec\u201d\uff09\u4e8e2021\u5e74\u5f00\u5c55\u4e86\u4e00\u9879I\u671f\u5355\u5242\u91cf\u9012\u589e\u8bd5\u9a8c\uff0c\u91c7\u7528\u6765\u81ea\u5065\u5eb7\u4f9b\u4f53\u7684\u540c\u79cd\u5f02\u4f53\u9aa8\u9ad3\u6765\u6e90MSCs\uff08allo-hMSCs\uff09\u3002\u8be5\u7b56\u7565\u5145\u5206\u5229\u7528\u4e86\u201c\u73b0\u6210\u201d\u540c\u79cd\u5f02\u4f53\u7ec6\u80de\u7684\u4f18\u52bf\uff0c\u5305\u62ec\u53ef\u5b9e\u73b0\u5927\u89c4\u6a21\u751f\u4ea7\u3001\u65e0\u9700\u8fdb\u884c\u60a3\u8005\u4e2a\u4f53\u5316\u7684\u7ec6\u80de\u91c7\u96c6\uff0c\u4ee5\u53ca\u80fd\u63d0\u4f9b\u66f4\u5e74\u8f7b\u3001\u6d3b\u6027\u66f4\u9ad8\u7684\u7ec6\u80de\uff0c\u4ece\u800c\u51cf\u5c11\u56e0\u4f9b\u4f53\u8870\u8001\u5e26\u6765\u7684\u6f5c\u5728\u98ce\u9669<sup>[1]<\/sup>\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924200121-68d3dd91a5071.png\" alt=\"\" title=\"\"><figcaption><\/figcaption><\/figure>\n<p>\u8bd5\u9a8c\u7ed3\u679c\u663e\u793a\uff0c\u5728\u8f7b\u4e2d\u5ea6PD\u60a3\u8005\u4e2d\uff0c\u5355\u6b21\u9759\u8109\u8f93\u6ce81\u201310\u00d710\u2076allo-MSCs\/kg\u5242\u91cf\u5b89\u5168\u4e14\u8010\u53d7\u826f\u597d\uff0c\u672a\u5f15\u53d1\u514d\u75ab\u539f\u6027\u53cd\u5e94\u3002\u63a2\u7d22\u6027\u5206\u6790\u8868\u660e\uff0c<strong>\u63a5\u53d7\u6700\u9ad8\u5242\u91cf\uff0810\u00d710\u2076cells\/kg\uff09\u7684\u60a3\u8005\u5728\u8f93\u6ce8\u540e3\u300112\u300124\u53ca52\u5468\u7684\u201c\u505c\u836f\u201d\u72b6\u6001\u4e0b\uff0c\u5176\u7edf\u4e00\u5e15\u91d1\u68ee\u75c5\u8bc4\u5b9a\u91cf\u8868\uff08UPDRS\uff09\u8fd0\u52a8\u8bc4\u5206\u5747\u663e\u793a\u6539\u5584\uff0c\u5e76\u4e14\u75c7\u72b6\u83b7\u76ca\u968f\u65f6\u95f4\u4fdd\u6301\u7a33\u5b9a<\/strong>\u3002<\/p>\n<p>\u57fa\u4e8e\u8fd9\u4e9b\u9f13\u821e\u4eba\u5fc3\u7684\u7ed3\u679c\uff0c\u5e76\u7ed3\u5408\u5e15\u91d1\u68ee\u75c5\u6162\u6027\u8fdb\u5c55\u7684\u7279\u6027\uff0c\u6211\u4eec\u63d0\u51fa\u5047\u8bbe\uff1a\u53cd\u590d\u8f93\u6ce8\u6700\u9ad8\u5b89\u5168\u5242\u91cf\u7684allo-hMSCs\u53ef\u80fd\u4f1a\u589e\u5f3a\u548c\u7ef4\u6301\u5176\u514d\u75ab\u8c03\u8282\u6548\u5e94\uff0c\u4ece\u800c\u5e26\u6765\u66f4\u663e\u8457\u3001\u66f4\u6301\u4e45\u7684\u4e34\u5e8a\u75c7\u72b6\u6539\u5584\u3002<\/p>\n<p>\u4e3a\u9a8c\u8bc1\u8be5\u5047\u8bbe\uff0c\u6211\u4eec\u7275\u5934\u5f00\u5c55\u4e86\u4e00\u9879II\u671f\u53cc\u76f2\u3001\u968f\u673a\u3001\u5b89\u6170\u5242\u5bf9\u7167\u8bd5\u9a8c\uff0c\u65e8\u5728\u8bc4\u4f30\u91cd\u590dallo-hMSC\u8f93\u6ce8\u5bf9\u6539\u5584PD\u60a3\u8005\u8fd0\u52a8\u53ca\u975e\u8fd0\u52a8\u75c7\u72b6\u7684\u7597\u6548\u3002\uff08\u7814\u7a76\u7ed3\u679c\u53d1\u8868\u5728\u671f\u520a\u6742\u5fd7\u300a<a href=\"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.70028\" target=\"_blank\" rel=\"nofollow noopener\">\u8fd0\u52a8\u969c\u788d\u4e3b\u9875<\/a>\u300b\u4e0a\uff09<sup>[2]<\/sup>\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924200121-68d3dd91b2ca6.png\" alt=\"\" title=\"\"><figcaption><\/figcaption><\/figure>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"II%E6%9C%9F%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%E6%A6%82%E5%86%B5\"><\/span><strong>II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u6982\u51b5<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>\u7814\u7a76\u8bbe\u8ba1\u4e0e\u65b9\u6cd5\uff1a<\/strong>\u5728\u8fd9\u9879II\u671f\u968f\u673a\u5b89\u6170\u5242\u5bf9\u7167\u8bd5\u9a8c\uff082020\u5e7411\u6708\u81f32023\u5e747\u6708\uff09\u4e2d\uff0c\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u5e15\u91d1\u68ee\u75c5\u60a3\u8005\u63a5\u53d7\u4e09\u6b21\u5f02\u57fa\u56e0hMSC\u8f93\u6ce8\uff0c\u4e00\u6b21\u5b89\u6170\u5242\u8f93\u6ce8\u540e\u518d\u8fdb\u884c\u4e24\u6b21\u5f02\u57fa\u56e0hMSC\u8f93\u6ce8\uff0c\u6216\u4ee518\u5468\u4e3a\u95f4\u9694\u8fdb\u884c\u4e09\u6b21\u5b89\u6170\u5242\u8f93\u6ce8\uff0c\u968f\u8bbf\u6301\u7eed88\u5468\u3002<\/p>\n<p>\u4e3b\u8981\u7ed3\u5c40\u6307\u6807\u4e3a\u7b2c62\u5468\u65f6\uff0c\u5728\u505c\u836f\u540e\u8fd0\u52a8\u969c\u788d\u534f\u4f1a\u4e3b\u529e\u7684\u7edf\u4e00\u5e15\u91d1\u68ee\u75c5\u8bc4\u5b9a\u91cf\u8868\u7b2c\u4e09\u90e8\u5206\u4fee\u8ba2\u7248\uff08MDS-UPDRS-III\uff09\u4e2d\uff0c\u60a3\u8005\u6bd4\u4f8b\u6539\u5584\u22655\u5206\u7684\u540e\u9a8c\u6982\u7387(PP)\u5dee\u5f02\u662f\u5426\u5927\u4e8e70%\u3002\u4f7f\u7528Rv4.2.0\u8fdb\u884c\u8d1d\u53f6\u65af\u5206\u6790\u3002<\/p>\n<p><strong>\u8bd5\u9a8c\u4eba\u7fa4\uff1a<\/strong>\u603b\u5171\u6709160\u540d\u60a3\u8005\u63a5\u53d7\u4e86\u9884\u7b5b\u9009\uff0c49\u540d\u63a5\u53d7\u4e86\u7b5b\u9009\uff0c45\u540d\u6700\u7ec8\u5165\u7ec4\u3002\u5176\u4e2d\uff0c16\u540d\u63a5\u53d7\u4e86\u4e09\u6b21\u5f02\u57fa\u56e0hMSC\u8f93\u6ce8\uff0c14\u540d\u63a5\u53d7\u4e86\u4e00\u6b21\u5b89\u6170\u5242\u8f93\u6ce8\uff0c\u968f\u540e\u53c8\u63a5\u53d7\u4e86\u4e24\u6b21\u5f02\u57fa\u56e0hMSC\u8f93\u6ce8\uff0c15\u540d\u63a5\u53d7\u4e86\u4e09\u6b21\u5b89\u6170\u5242\u8f93\u6ce8\u3002\u57fa\u7ebf\u4eba\u53e3\u7edf\u8ba1\u5b66\u548c\u4e34\u5e8a\u7279\u5f81\u89c1\u88681\u3002<\/p>\n<p>\u5230\u7b2c62\u5468\uff0c42\u540d\u60a3\u8005\u5b8c\u6210\u4e86\u6240\u6709\u8f93\u6ce8\u548c\u8bc4\u4f30\uff1b\u4e24\u540d\u60a3\u8005\u9000\u51fa\uff0c\u4e00\u540d\u60a3\u8005\u5728\u88ab\u8bca\u65ad\u4e3a\u591a\u7cfb\u7edf\u840e\u7f29\uff08\u7ecf\u03b1Syn-SAA\u8bc1\u5b9e\uff09\u540e\u88ab\u6392\u9664\u5728\u5916\u3002\u53e6\u5916\u4e24\u540d\u60a3\u8005\u56e0\u4e0d\u76f8\u5173\u7684\u5065\u5eb7\u95ee\u9898\u505c\u6b62\u7814\u7a76\uff0c\u5269\u4e0b40\u540d\u60a3\u8005\u5b8c\u6210\u4e8688\u5468\u7684\u968f\u8bbf\uff08\u56fe1\uff09\u3002<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 2138px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924200121-68d3dd91c2638.jpg\" alt=\"\u56fe1\uff1a\u7814\u7a76\u6d41\u7a0b\" width=\"2128\" height=\"1289\" title=\"\"><p class=\"wp-caption-text\">\u56fe1\uff1a\u7814\u7a76\u6d41\u7a0b<\/p><\/div><figcaption><\/figcaption><\/figure>\n<h2><span class=\"ez-toc-section\" id=\"%E5%90%8C%E7%A7%8D%E5%BC%82%E4%BD%93%E9%AA%A8%E9%AB%93%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E5%B8%95%E9%87%91%E6%A3%AE%E7%97%85%E7%9A%84%E4%B8%BB%E8%A6%81%E7%BB%93%E6%9E%9C\"><\/span><strong>\u540c\u79cd\u5f02\u4f53\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u4e3b\u8981\u7ed3\u679c<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%AC%AC62%E5%91%A8%E8%BF%90%E5%8A%A8%E7%97%87%E7%8A%B6%E6%94%B9%E5%96%84%E7%9A%84%E7%BB%84%E9%97%B4%E5%B7%AE%E5%BC%82\"><\/span><strong>\u7b2c62\u5468\u8fd0\u52a8\u75c7\u72b6\u6539\u5584\u7684\u7ec4\u95f4\u5dee\u5f02<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>\u4e09\u6b21\u8f93\u6ce8\u5728\u7b2c62\u5468\u7684\u4e34\u5e8a\u91cd\u8981\u6539\u5584\uff1a<\/strong>\u7b2c62\u5468\u65f6\uff0c<strong>\u4e09\u6b21\u8f93\u6ce8\u7ec4\u4e2dMDS-UPDRS-III\u8fd0\u52a8\u8bc4\u5206\u6539\u5584\u22655\u5206\u7684\u53d7\u8bd5\u8005\u6bd4\u4f8b\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\u6709\u6240\u589e\u52a0\uff08\u56fe2A\uff09<\/strong>\u3002\u4f7f\u7528\u66f4\u4e25\u683c\u7684\u9608\u503c\uff08\u226511\u5206\uff09\uff0c\u4e09\u6b21\u8f93\u6ce8\u7ec4\u4e2d\u6539\u5584\u7684\u53d7\u8bd5\u8005\u6bd4\u4f8b\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\u6709\u6240\u589e\u52a0\uff08\u56fe2B\uff09\u3002<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 2138px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924200122-68d3dd9281fce.jpg\" alt=\"\u56fe2\uff1a\u63a5\u53d7\u4eba\u540c\u79cd\u5f02\u4f53\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de (allo-hMSCs) \u6cbb\u7597\u540e\uff0c\u5e15\u91d1\u68ee\u75c5\u60a3\u8005\u5728\u8fd0\u52a8\u969c\u788d\u534f\u4f1a\u4e3b\u529e\u7684\u7edf\u4e00\u5e15\u91d1\u68ee\u75c5\u8bc4\u5b9a\u91cf\u8868\u7b2c\u4e09\u90e8\u5206\u4fee\u8ba2\u7248 (MDS-UPDRS-III) \u8bc4\u5206\u4e2d\u83b7\u5f97\u4e2d\u5ea6\u6216\u8f83\u5927\u4e34\u5e8a\u91cd\u8981\u6027\u6539\u5584\u7684\u6bd4\u4f8b\u3002\" width=\"2128\" height=\"2184\" title=\"\"><p class=\"wp-caption-text\">\u56fe2\uff1a\u63a5\u53d7\u4eba\u540c\u79cd\u5f02\u4f53\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de (allo-hMSCs) \u6cbb\u7597\u540e\uff0c\u5e15\u91d1\u68ee\u75c5\u60a3\u8005\u5728\u8fd0\u52a8\u969c\u788d\u534f\u4f1a\u4e3b\u529e\u7684\u7edf\u4e00\u5e15\u91d1\u68ee\u75c5\u8bc4\u5b9a\u91cf\u8868\u7b2c\u4e09\u90e8\u5206\u4fee\u8ba2\u7248 (MDS-UPDRS-III) \u8bc4\u5206\u4e2d\u83b7\u5f97\u4e2d\u5ea6\u6216\u8f83\u5927\u4e34\u5e8a\u91cd\u8981\u6027\u6539\u5584\u7684\u6bd4\u4f8b\u3002<\/p><\/div><figcaption><\/figcaption><\/figure>\n<p><strong>\u4e24\u6b21\u8f93\u6ce8\u7ec4\u7684\u8d1f\u9762\u7597\u6548\u8868\u73b0\uff1a<\/strong>\u76f8\u53cd\uff0c\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\uff0c\u4e24\u6b21\u8f93\u6ce8\u7ec4\u4e2d\u8fbe\u5230\u22655\u5206\uff08\u56fe2A\uff09\u548c\u226511\u5206\uff08\u56fe2B\uff09\u9608\u503c\u7684\u53d7\u8bd5\u8005\u8f83\u5c11\u3002\u867d\u7136\u7f6e\u4fe1\u533a\u95f4\u5b58\u5728\u4e00\u5b9a\u4ea4\u53c9\uff0c\u4f46\u603b\u4f53\u8d8b\u52bf\u652f\u6301\u4e09\u6b21\u8f93\u6ce8\u65b9\u6848\u7684\u6f5c\u5728\u83b7\u76ca\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E5%90%8C%E7%A7%8D%E5%BC%82%E4%BD%93%E9%AA%A8%E9%AB%93%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E5%B8%95%E9%87%91%E6%A3%AE%E7%97%85%E7%9A%84%E6%AC%A1%E8%A6%81%E7%BB%93%E5%B1%80\"><\/span><strong>\u540c\u79cd\u5f02\u4f53\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u6b21\u8981\u7ed3\u5c40<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5176\u4ed6\u6b21\u8981\u4e34\u5e8a\u7ed3\u5c40\u7684\u7ed3\u679c\uff0c\u5305\u62ec\u4ece\u57fa\u7ebf\u8d77MDS-UPDRS\u5404\u90e8\u5206\uff08I\u3001II\u3001III\u3001IV\uff09\u3001\u603b\u5206\u3001PDQ-39\u4ee5\u53caEQ-5D-5L\u6307\u6570\u8bc4\u5206\u7684\u53d8\u5316\uff0c\u89c1\u88682\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"MDS-UPDRS-III%E8%AF%84%E5%88%86%E5%8F%98%E5%8C%96%E8%B6%8B%E5%8A%BF%EF%BC%9A%E4%BB%8E%E5%9F%BA%E7%BA%BF%E5%88%B0%E7%AC%AC88%E5%91%A8\"><\/span><strong>MDS-UPDRS-III\u8bc4\u5206\u53d8\u5316\u8d8b\u52bf\uff1a\u4ece\u57fa\u7ebf\u5230\u7b2c88\u5468<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u81f3\u7b2c62\u5468\uff0c<strong>\u4e09\u6b21\u8f93\u6ce8\u7ec4\u8bc4\u5206\u8f83\u57fa\u7ebf\u6539\u558416.9\u5206\uff0c\u63a5\u8fd1\u5b89\u6170\u5242\u7ec4\u768414.6\u5206\u6539\u5584<\/strong>\uff0c\u4e24\u7ec4\u95f4\u5dee\u5f02\u4ec5\u4e3a2.3\u5206\u3002\u800c\u4e24\u6b21\u8f93\u6ce8\u7ec4\u4ec5\u6539\u55843.9\u5206\uff0c\u663e\u8457\u52a3\u4e8e\u5b89\u6170\u5242\u7ec4\uff08\u7ec4\u95f4\u5dee\u5f02+20.6\u5206\uff09\u3002<strong>\u8fd9\u4e00\u8d8b\u52bf\u6301\u7eed\u81f3\u7b2c88\u5468\uff0c\u4e09\u6b21\u8f93\u6ce8\u7ec4\u4f18\u52bf\u6269\u5927\u81f33.3\u5206\uff08\u88682\uff09<\/strong>\u3002\u5404\u8bbf\u89c6\u65f6\u5e73\u5747MDS-UPDRS-III\u8bc4\u5206\u7684\u53d8\u5316\u6c47\u603b\u4e8e\u56fe3\u3002<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 2138px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924200123-68d3dd93bd171.jpg\" alt=\"\u56fe3\uff1a\u8fd0\u52a8\u969c\u788d\u534f\u4f1a\u4e3b\u529e\u7684\u7edf\u4e00\u5e15\u91d1\u68ee\u75c5\u8bc4\u5b9a\u91cf\u8868\u7b2c\u4e09\u90e8\u5206 (MDS-UPDRS-III) \u4fee\u8ba2\u7248\u5404\u6cbb\u7597\u7ec4\u7684\u6539\u5584\u8f68\u8ff9\u3002\" width=\"2128\" height=\"917\" title=\"\"><p class=\"wp-caption-text\">\u56fe3\uff1a\u8fd0\u52a8\u969c\u788d\u534f\u4f1a\u4e3b\u529e\u7684\u7edf\u4e00\u5e15\u91d1\u68ee\u75c5\u8bc4\u5b9a\u91cf\u8868\u7b2c\u4e09\u90e8\u5206 (MDS-UPDRS-III) \u4fee\u8ba2\u7248\u5404\u6cbb\u7597\u7ec4\u7684\u6539\u5584\u8f68\u8ff9\u3002<\/p><\/div><figcaption><\/figcaption><\/figure>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E9%95%BF%E6%9C%9F%E7%96%97%E6%95%88%EF%BC%9A%E7%AC%AC88%E5%91%A8%E4%B8%B4%E5%BA%8A%E5%B7%AE%E5%BC%82%E6%8C%81%E7%BB%AD%E6%89%A9%E5%A4%A7\"><\/span><strong>\u957f\u671f\u7597\u6548\uff1a\u7b2c88\u5468\u4e34\u5e8a\u5dee\u5f02\u6301\u7eed\u6269\u5927<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u5728\u7b2c88\u5468\uff0c<strong>\u4e09\u6b21\u8f93\u6ce8\u7ec4\u4e2d\u66f4\u591a\u53d7\u8bd5\u8005\u8fbe\u5230\u81f3\u5c115\u5206\u6539\u5584<\/strong>\uff08\u7ec4\u95f4\u5dee\u5f0211.5%\uff0c\u540e\u9a8c\u6982\u738798.4%\uff0c\u56fe2A\uff09\u548c11\u5206\u6539\u5584\uff08\u7ec4\u95f4\u5dee\u5f0242.4%\uff0c\u540e\u9a8c\u6982\u7387\u226599.9%\uff0c\u56fe2B\uff09\uff0c\u5747\u4f18\u4e8e\u5b89\u6170\u5242\u7ec4\u3002<\/p>\n<p>\u76f8\u53cd\uff0c<strong>\u4e24\u6b21\u8f93\u6ce8\u7ec4\u53d7\u8bd5\u8005\u8fbe\u52305\u5206\u6539\u5584<\/strong>\uff08\u7ec4\u95f4\u5dee\u5f0254.6%\uff0c\u540e\u9a8c\u6982\u738799.9%\uff0c\u56fe2A\uff09\u548c11\u5206\u6539\u5584\uff08MD\uff1a\u221243.1%\uff0c95%CrI\uff1a\u221269.8%\u81f3 \u221213.6%\uff0cPP=99.7%\uff1b\u56fe2B\uff09\u7684\u6bd4\u4f8b\u5747\u4f4e\u4e8e\u5b89\u6170\u5242\u7ec4\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%80%BB%E4%BD%93%E8%AF%84%E4%BC%B0%EF%BC%9AMDS-UPDRS%E6%80%BB%E5%88%86%E7%9A%84%E6%94%B9%E5%96%84\"><\/span><strong>\u603b\u4f53\u8bc4\u4f30\uff1aMDS-UPDRS\u603b\u5206\u7684\u6539\u5584<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u5728<strong>\u603b\u5206\u6539\u5584\u65b9\u9762\uff0c\u4e09\u6b21\u8f93\u6ce8\u7ec4\u5728\u7b2c62\u5468\u65f6\u6709\u66f4\u591a\u53c2\u4e0e\u8005\u8fbe\u5230\u81f3\u5c1112\u5206\u6539\u5584<\/strong>\uff08MD\uff1a22.0%\uff0c95%CrI\uff1a\u221221.0%\u81f349.4%\uff0cPP=96.3%\uff09\uff0c\u5728\u7b2c88\u5468\u6539\u5584\u66f4\u4e3a\u663e\u8457\uff08MD\uff1a48.4%\uff0c95%CrI\uff1a23.9%\u81f374.0%\uff0cPP\u226599.9%\uff09\u3002<\/p>\n<p>\u76f8\u53cd\uff0c\u4e24\u6b21\u8f93\u6ce8\u7ec4\u5728\u7b2c62\u5468\uff08MD\uff1a\u221243.0%\uff0c95%CrI\uff1a\u221271.2%\u81f3 \u22128.3%\uff0cPP=99.1%\uff09\u548c\u7b2c88\u5468\uff08MD\u221220.8%\uff0c95%CrI\uff1a\u221253.1%\u81f314.1%\uff0cPP=87.8%\uff09\u5747\u52a3\u4e8e\u5b89\u6170\u5242\u7ec4\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%B2%BB%E7%96%97%E5%AE%89%E5%85%A8%E6%80%A7%E4%B8%8E%E5%85%8D%E7%96%AB%E5%8F%8D%E5%BA%94%E8%AF%84%E4%BC%B0\"><\/span><strong>\u6cbb\u7597\u5b89\u5168\u6027\u4e0e\u514d\u75ab\u53cd\u5e94\u8bc4\u4f30<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u5b89\u5168\u6027\u7ed3\u679c\u662f\u672c\u7814\u7a76\u7684\u4eae\u70b9\u4e4b\u4e00\u3002\u6574\u4e2a\u7814\u7a76\u671f\u95f4\uff1a\u5171\u62a5\u544a10\u4f8b\u8f7b\u5fae\u3001\u77ed\u6682\u7684\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\uff0c\u65e0\u4efb\u4f55\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff08SAEs\uff09\u53d1\u751f\u3002\u4e09\u6b21\u8f93\u6ce8\u7ec4\u62a5\u544a\u4e86\u4e2a\u522b\u4e0d\u9002\u75c7\u72b6\uff08\u5982\u5168\u8eab\u4e0d\u9002\u3001\u77ed\u6682\u6027\u9ad8\u8840\u538b\uff09\u3002\u4e24\u6b21\u8f93\u6ce8\u7ec4\u62a5\u544a\u7684\u75c7\u72b6\u5747\u4e3a\u81ea\u9650\u6027\u7684\u5168\u8eab\u75c7\u72b6\uff08\u5982\u75b2\u52b3\u3001\u6d41\u611f\u6837\u75c7\u72b6\uff09\uff0c\u5747\u81ea\u884c\u7f13\u89e3\u3002<\/p>\n<p>\u8d77\u521d\u6709\u4e09\u4f8b\u7591\u4f3c\u4f9b\u8005\u7279\u5f02\u6027\u6297\u4f53\uff08DSA\uff09\u7684\u53cd\u5e94\uff0c\u7ecf\u540e\u7eedHLA\u5206\u578b\u786e\u8ba4\u5747\u4e0e\u6cbb\u7597\u65e0\u5173\uff0c\u5176\u4e2d\u4e00\u4f8b\u5b9e\u9645\u6765\u81ea\u5b89\u6170\u5242\u7ec4\u3002<\/p>\n<p>\u7ed3\u679c\u8868\u660e\uff0c<strong>\u91cd\u590d\u8f93\u6ce8\u540c\u79cd\u5f02\u4f53hMSCs\u5b89\u5168\u4e14\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u5f15\u53d1\u663e\u8457\u7684\u514d\u75ab\u539f\u6027\u6216\u4efb\u4f55\u81f4\u7624\u6027\u62c5\u5fe7<\/strong>\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E7%BB%BC%E5%90%88%E8%AE%A8%E8%AE%BA%EF%BC%9A%E7%96%97%E6%95%88%E5%B7%AE%E5%BC%82%E7%9A%84%E8%A7%A3%E8%AF%BB%E4%B8%8E%E5%90%AF%E7%A4%BA\"><\/span><strong>\u7efc\u5408\u8ba8\u8bba\uff1a\u7597\u6548\u5dee\u5f02\u7684\u89e3\u8bfb\u4e0e\u542f\u793a<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%BB%E8%A6%81%E7%96%97%E6%95%88%E7%BB%93%E6%9E%9C%EF%BC%9A%E4%B8%89%E6%AC%A1%E8%BE%93%E6%B3%A8%E7%BB%84%E6%98%BE%E8%91%97%E4%BC%98%E4%BA%8E%E5%AE%89%E6%85%B0%E5%89%82\"><\/span><strong>\u4e3b\u8981\u7597\u6548\u7ed3\u679c\uff1a\u4e09\u6b21\u8f93\u6ce8\u7ec4\u663e\u8457\u4f18\u4e8e\u5b89\u6170\u5242<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u5206\u6790\u663e\u793a\uff0c\u4e3b\u8981\u7597\u6548\u7ed3\u679c\u5df2\u8fbe\u5230\u3002<strong>\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\uff0c\u63a5\u53d7\u4e09\u6b21\u8f93\u6ce8\u7684\u6cbb\u7597\u7ec4\u5728\u7b2c62\u5468\u65f6\u6709\u66f4\u9ad8\u6bd4\u4f8b\u7684\u60a3\u8005\u5b9e\u73b0MDS-UPDRS-III\u8bc4\u5206\u22655\u5206\uff08\u9ad8\u51fa5%\uff09\u548c\u226511\u5206\uff08\u9ad8\u51fa13.3%\uff09\u7684\u6539\u5584<\/strong>\uff0c\u4e14\u8be5\u4f18\u52bf\u5230\u7b2c88\u5468\u65f6\u8fdb\u4e00\u6b65\u6269\u5927\uff08\u5206\u522b\u9ad8\u51fa11.5%\u548c42.4%\uff09\uff0c\u540e\u9a8c\u6982\u7387\u5747\u9ad8\u4e8e91.5%\uff0c\u663e\u793a\u51fa\u5f3a\u70c8\u7684\u7edf\u8ba1\u5b66\u610f\u4e49\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%B5%B7%E6%95%88%E6%97%B6%E9%97%B4%E4%B8%8E%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6%E6%8E%A8%E6%B5%8B\"><\/span><strong>\u8d77\u6548\u65f6\u95f4\u4e0e\u4f5c\u7528\u673a\u5236\u63a8\u6d4b<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u4e09\u6b21\u8f93\u6ce8\u7ec4\u8d77\u6548\u8fc5\u901f\uff0c<strong>\u9996\u6b21\u8f93\u6ce8\u540e9\u5468\u5373\u89c2\u5bdf\u5230\u663e\u8457\u8fd0\u52a8\u75c7\u72b6\u6539\u5584\uff08\u964d\u4f4e12.9\u5206\uff09\uff0c\u8fd9\u8868\u660e\u540c\u79cd\u5f02\u4f53hMSC\u53ef\u80fd\u5728\u7ed9\u836f\u540e\u901a\u8fc7\u5feb\u901f\u8c03\u8282\u514d\u75ab\u5fae\u73af\u5883\u53d1\u6325\u6cbb\u7597\u4f5c\u7528<\/strong>\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u4e24\u6b21\u8f93\u6ce8\u7ec4\u6548\u679c\u5ef6\u8fdf\u4e14\u5fae\u5f31\uff0c\u63a8\u6d4b\u8f83\u665a\u8f93\u6ce8\u65f6\u708e\u75c7\u73af\u5883\u5df2\u6539\u53d8\uff0c\u53ef\u80fd\u5bfc\u81f4\u7ec6\u80de\u7597\u6548\u964d\u4f4e\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%A4%E6%AC%A1%E8%BE%93%E6%B3%A8%E7%BB%84%E7%96%97%E6%95%88%E6%AC%A0%E4%BD%B3%E7%9A%84%E5%8F%AF%E8%83%BD%E8%A7%A3%E9%87%8A\"><\/span><strong>\u4e24\u6b21\u8f93\u6ce8\u7ec4\u7597\u6548\u6b20\u4f73\u7684\u53ef\u80fd\u89e3\u91ca<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u8be5\u7ec4\u7597\u6548\u4f4e\u4e8e\u5b89\u6170\u5242\u7684\u73b0\u8c61\u503c\u5f97\u6df1\u5165\u63a2\u8ba8\uff0c\u53ef\u80fd\u539f\u56e0\u5305\u62ec\uff1a<\/p>\n<p><strong>\u5f3a\u5927\u7684\u5b89\u6170\u5242\u6548\u5e94\uff1a<\/strong>\u5b89\u6170\u5242\u7ec4\u663e\u793a\u4e86\u6301\u7eed\u4e14\u663e\u8457\u7684\u6539\u5584\uff08\u6539\u558414.6\u5206\uff09\uff0c\u8fd9\u53ef\u80fd\u63a9\u76d6\u4e86\u4e24\u6b21\u8f93\u6ce8\u65b9\u6848\u5e26\u6765\u7684\u5fae\u5c0f\u83b7\u76ca\u3002<\/p>\n<p><strong>\u8f93\u6ce8\u65f6\u673a\u4e0e\u514d\u75ab\u73af\u5883\uff1a<\/strong>\u63a8\u6d4b\u9996\u6b21\u8f93\u6ce8\u5b89\u6170\u5242\u65f6\uff0c\u60a3\u8005\u5904\u4e8e\u66f4\u5177\u53cd\u5e94\u6027\u7684\u708e\u75c7\u72b6\u6001\uff0c\u800c\u5ef6\u8fdf\u8f93\u6ce8\u6d3b\u6027\u7ec6\u80de\u65f6\uff0c\u514d\u75ab\u73af\u5883\u53ef\u80fd\u5df2\u53d1\u751f\u6539\u53d8\uff0c\u5bfc\u81f4\u7ec6\u80de\u7597\u6548\u964d\u4f4e\u3002<\/p>\n<p><strong>\u6279\u6b21\u95f4\u53d8\u5f02\u6027\uff1a<\/strong>\u4e0d\u540c\u751f\u4ea7\u6279\u6b21\u7684MSCs\u5728\u529f\u80fd\u6548\u4ef7\u4e0a\u53ef\u80fd\u5b58\u5728\u5dee\u5f02\uff0c\u5f71\u54cd\u4e86\u6cbb\u7597\u6548\u679c\u7684\u4e00\u81f4\u6027\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%94%9F%E6%B4%BB%E8%B4%A8%E9%87%8F%E6%8C%87%E6%A0%87%E4%B8%8E%E5%A4%9A%E7%BB%B4%E8%AF%84%E4%BC%B0%E7%9A%84%E9%87%8D%E8%A6%81%E6%80%A7\"><\/span><strong>\u751f\u6d3b\u8d28\u91cf\u6307\u6807\u4e0e\u591a\u7ef4\u8bc4\u4f30\u7684\u91cd\u8981\u6027<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u9664\u4e86<strong>\u8fd0\u52a8\u8bc4\u5206\uff0cPDQ-39\u548cEQ-5D-5L\u7b49\u751f\u6d3b\u8d28\u91cf\u6307\u6807\u663e\u793a\uff0c\u6cbb\u7597\u7ec4\u5728\u60a3\u8005\u65e5\u5e38\u529f\u80fd\u548c\u5e78\u798f\u611f\u65b9\u9762\u4f18\u4e8e\u5b89\u6170\u5242\u7ec4\uff0c\u4e14\u6539\u5584\u6301\u7eed\u66f4\u4e45<\/strong>\u3002\u8fd9\u51f8\u663e\u4e86\u8fd0\u52a8\u8bc4\u4f30\uff08MDS-UPDRS-III\uff09\u5b58\u5728\u5c40\u9650\u6027\uff0c\u5728PD\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7eb3\u5165\u60a3\u8005\u62a5\u544a\u7684\u751f\u6d3b\u8d28\u91cf\u7b49\u591a\u7ef4\u7ec8\u70b9\u81f3\u5173\u91cd\u8981\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E7%BB%93%E8%AE%BA\"><\/span><strong>\u7ed3\u8bba<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u636e\u6211\u4eec\u6240\u77e5\uff0c\u8fd9\u662f\u9996\u4e2a\u91c7\u7528\u4e09\u6b21\u91cd\u590d\u9759\u8109\u6ce8\u5c04\u5242\u91cf\uff08\u6bcf\u6b2110\u00d710^6\u4e2a\u5f02\u57fa\u56e0\u4eba\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\/\u5343\u514b\uff09\u7684\u968f\u673a\u3001\u5b89\u6170\u5242\u5bf9\u7167\u8bd5\u9a8c\u3002<\/p>\n<p><strong>\u8be5\u7814\u7a76\u8fbe\u5230\u4e86\u5176\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff1a<\/strong>\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0c\u4e09\u6b21\u6ce8\u5c04\u5242\u91cf\uff08\u6bcf\u6b2110\u00d710 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