{"id":19232,"date":"2025-09-25T04:17:34","date_gmt":"2025-09-24T12:17:34","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/stem-cells\/nsc\/19232.html"},"modified":"2025-10-13T15:33:42","modified_gmt":"2025-10-13T07:33:42","slug":"https-www-hjtdsm-cn-stem-cells-nsc-19232-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19232.html","title":{"rendered":"\u0645\u062c\u0644\u0629 \u0639\u0644\u0645 \u0627\u0644\u0623\u0637\u0631\u0627\u0641 \u0627\u0644\u0635\u0646\u0627\u0639\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629: \u0627\u0644\u062a\u0642\u062f\u0645 \u0627\u0644\u0645\u062d\u0631\u0632 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u0632\u0631\u0627\u0639\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629\/\u0627\u0644\u0645\u062a\u0648\u0644\u062f\u0629 \u0641\u064a \u0625\u0635\u0627\u0628\u0627\u062a \u0627\u0644\u062d\u0628\u0644 \u0627\u0644\u0634\u0648\u0643\u064a \u0627\u0644\u0645\u0632\u0645\u0646\u0629"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 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\u0627\u0644\u062d\u0628\u0644 \u0627\u0644\u0634\u0648\u0643\u064a \u0627\u0644\u0645\u0632\u0645\u0646\u0629<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19232.html\/#%E7%A0%94%E7%A9%B6%E8%83%8C%E6%99%AF\" >\u7814\u7a76\u80cc\u666f<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19232.html\/#%E5%95%AE%E9%BD%BF%E5%8A%A8%E7%89%A9%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%A5%96%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E6%85%A2%E6%80%A7%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E5%B7%B2%E6%98%BE%E7%A4%BA%E5%88%9D%E6%AD%A5%E7%96%97%E6%95%88\" 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style=\"vertical-align: inherit;\">\u0645\u062c\u0644\u0629 \u0639\u0644\u0645 \u0627\u0644\u0623\u0637\u0631\u0627\u0641 \u0627\u0644\u0635\u0646\u0627\u0639\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629: \u0627\u0644\u062a\u0642\u062f\u0645 \u0627\u0644\u0645\u062d\u0631\u0632 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u0632\u0631\u0627\u0639\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629\/\u0627\u0644\u0645\u062a\u0648\u0644\u062f\u0629 \u0641\u064a \u0625\u0635\u0627\u0628\u0627\u062a \u0627\u0644\u062d\u0628\u0644 \u0627\u0644\u0634\u0648\u0643\u064a \u0627\u0644\u0645\u0632\u0645\u0646\u0629<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u662f\u4e00\u79cd\u4e25\u91cd\u7684\u81f4\u6b8b\u6027\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\uff0c\u53ef\u5bfc\u81f4\u6d3b\u52a8\u80fd\u529b\u53d7\u635f\u3001\u611f\u89c9\u529f\u80fd\u7d0a\u4e71\u548c\u81ea\u4e3b\u795e\u7ecf\u529f\u80fd\u969c\u788d\u3002\u795e\u7ecf\u5e72\u7ec6\u80de\/\u7956\u7ec6\u80de\uff08NSPC\uff09\u79fb\u690d\u88ab\u8ba4\u4e3a\u662f\u4fc3\u8fdb\u529f\u80fd\u6062\u590d\u7684\u6709\u524d\u666f\u7684\u6cbb\u7597\u7b56\u7565\u3002\u5c3d\u7ba1\u591a\u6570\u7814\u7a76\u805a\u7126\u4e8eSCI\u65e9\u671f\u9636\u6bb5\uff0c\u4f46\u4e34\u5e8a\u4e0a\u5927\u591a\u6570\u60a3\u8005\u5904\u4e8e\u6162\u6027\u671f\uff0c\u9488\u5bf9\u6162\u6027SCI\u7684\u4e34\u5e8a\u8bd5\u9a8c\u66f4\u80fd\u63ed\u793a\u6f5c\u5728\u7597\u6548\u3002<\/span><\/span><\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%A0%94%E7%A9%B6%E8%83%8C%E6%99%AF\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7814\u7a76\u80cc\u666f<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8fd1\u671f\uff0c\u7531\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u5b66\u9662\u9644\u5c5e\u540c\u6d4e\u533b\u9662\u795e\u7ecf\u5916\u79d1\u9886\u8854\u7684\u591a\u673a\u6784\u56e2\u961f\uff0c\u5728\u56fd\u9645\u671f\u520a\u300a<\/span><\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2324242625000452\" target=\"_blank\" rel=\"nofollow noopener\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u795e\u7ecf\u4fee\u590d\u5b66\u6742\u5fd7<\/span><\/span><\/a><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u300b\u53d1\u8868\u7efc\u8ff0\uff0c\u7cfb\u7edf\u603b\u7ed3\u4e86\u4e0d\u540c\u6765\u6e90NSPC\u79fb\u690d\u6cbb\u7597\u6162\u6027SCI\u7684\u8fdb\u5c55[1]\uff1a<\/span><\/span><\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201733-68d3e15d26e6f.jpg\" alt=\"\u795e\u7ecf\u4fee\u590d\u5b66\u6742\u5fd7\uff1a\u795e\u7ecf\u5e72\/\u7956\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684\u4e34\u5e8a\u7814\u7a76\u8fdb\u5c55\" width=\"616\" height=\"599\" title=\"\"><figcaption><\/figcaption><\/figure>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u556e\u9f7f\u7c7bNSPC\u79fb\u690d<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5728\u635f\u4f24\u90e8\u4f4d\u53ef\u5b58\u6d3b\u3001\u5206\u5316\u5e76\u652f\u6301\u518d\u751f\uff0c\u4f46\u9700\u8054\u5408\u6cbb\u7597\u624d\u80fd\u8bf1\u5bfc\u529f\u80fd\u6027\u8fd0\u52a8\u6062\u590d\uff1b<\/span><\/span><\/p>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7bNSPC\u79fb\u690d<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff08\u5355\u72ec\u6216\u8054\u5408\u6cbb\u7597\uff09\u663e\u793a\u51fa\u663e\u7740\u6cbb\u7597\u6f5c\u529b\uff1b<\/span><\/span><\/p>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4ee5\u5b89\u5168\u6027\u548c\u53ef\u884c\u6027\u4e3a\u4e3b\u8981\u7ec8\u70b9\uff0c\u957f\u671f\u968f\u8bbf\u6570\u636e\u5448\u73b0\u79ef\u6781\u8d8b\u52bf\u3002<\/span><\/span><\/p>\n<h2 id=\"sectitle0025\"><span class=\"ez-toc-section\" id=\"%E5%95%AE%E9%BD%BF%E5%8A%A8%E7%89%A9%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%A5%96%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E6%85%A2%E6%80%A7%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E5%B7%B2%E6%98%BE%E7%A4%BA%E5%88%9D%E6%AD%A5%E7%96%97%E6%95%88\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u556e\u9f7f\u52a8\u7269\u795e\u7ecf\u5e72\/\u7956\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u5df2\u663e\u793a\u521d\u6b65\u7597\u6548<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: 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dir=\"auto\" style=\"vertical-align: inherit;\">\u4e3b\u8981\u5206\u5316\u4e3a\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u548c\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\uff1b<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u80da\u80ce\u5e72\u7ec6\u80de\uff08ESC\uff09\u6216\u80ce\u513f\u810a\u9ad3\u6765\u6e90\u7684NSPCs<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5219\u5177\u5907\u66f4\u5f3a\u7684\u795e\u7ecf\u5143\u5206\u5316\u6f5c\u80fd\uff1b\u800c<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u80ce\u513f\u5927\u8111\u76ae\u5c42NSPCs<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5219\u4ee5\u5206\u5316\u4e3a\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\u4e3a\u4e3b\u3002\u8fd9\u79cd\u5206\u5316\u503e\u5411\u6027\u8868\u660e\uff0c\u7ec6\u80de\u6765\u6e90\u662f\u51b3\u5b9a\u79fb\u690d\u540e\u795e\u7ecf\u8c31\u7cfb\u5b9a\u5411\u7684\u5173\u952e\u56e0\u7d20\u3002<\/span><\/span><\/p>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b58\u6d3b\u7387\u6311\u6218\u4e0e\u5e94\u7528\u5c40\u9650<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff1a\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7ecf\u4f53\u5916\u57f9\u517b\u6269\u589e\u7684NSPCs<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u79fb\u690d\u81f3\u6162\u6027\u80cc\u67f1\u635f\u4f24\u6a21\u578b\u540e\uff0c\u5176\u5b58\u6d3b\u7387\u663e\u7740\u4f4e\u4e8e<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u65b0\u9c9c\u5206\u79bb\u7684\u80ce\u513fCNS-NSPCs<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: 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id=\"%E5%AF%B9%E5%95%AE%E9%BD%BF%E7%B1%BB%E8%84%91%E6%BA%90%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%A5%96%E7%BB%86%E8%83%9E%E5%8D%95%E7%8B%AC%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E6%85%A2%E6%80%A7%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%EF%BC%88SCI%EF%BC%89%E7%96%97%E6%95%88%E5%B1%80%E9%99%90%E6%80%A7\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5bf9\u556e\u9f7f\u7c7b\u8111\u6e90\u795e\u7ecf\u5e72\/\u7956\u7ec6\u80de\u5355\u72ec\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u7597\u6548\u5c40\u9650\u6027<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b58\u6d3b\u4e0e\u6574\u5408\u7684\u77db\u76fe\u53ca\u5fae\u73af\u5883\u5f71\u54cd<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff1a\u5728\u6162\u6027SCI\u6a21\u578b\u4e2d\uff0c\u556e\u9f7f\u7c7b\u6210\u4f53\u8111\u6e90NSPCs\u7684\u521d\u59cb\u5b58\u6d3b\u7387\u8f83\u4f4e\uff0c\u53ef\u80fd\u4e0e\u6162\u6027\u671f\u5f62\u6210\u7684<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u661f\u5f62\u80f6\u8d28\u7622\u75d5\u53ca\u6291\u5236\u56e0\u5b50<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u963b\u788d\u7ec6\u80de\u8fc1\u79fb\u6574\u5408\u6709\u5173\u3002\u7136\u800c\uff0c\u90e8\u5206\u7814\u7a76\u663e\u793a\u6b64\u7c7b\u7ec6\u80de\u4ecd\u5177\u5907<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5f62\u6210\u795e\u7ecf\u5143\u4e2d\u7ee7\u7684\u6f5c\u529b<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: 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style=\"vertical-align: inherit;\">\u53ca<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u533a\u57df\u7279\u5f02\u6027\u9519\u914d<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u2014\u2014\u8111\u6e90\u7ec6\u80de\u96be\u4ee5\u9002\u5e94\u810a\u9ad3\u5fae\u73af\u5883\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u4eba\u7c7b\u7814\u7a76\u8bc1\u5b9e\uff1a\u5c06hESCs\/hiPSCs\u5b9a\u5411\u5206\u5316\u4e3a<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u810a\u9ad3\u578bNSPCs<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff08\u800c\u975e\u8111\u578b\uff09\u66f4\u80fd\u4fc3\u8fdb\u5bbf\u4e3b\u795e\u7ecf\u73af\u8def\u6574\u5408\u4e0e\u76ae\u8d28\u810a\u9ad3\u675f\u518d\u751f\u3002\u8fd9\u63ed\u793a\u4e86\u7ec6\u80de\u6765\u6e90\u7684\u533a\u57df\u9002\u914d\u6027\u5bf9\u529f\u80fd\u6062\u590d\u7684\u5173\u952e\u4f5c\u7528\u3002\u56e0\u6b64\uff0c\u5355\u72ec\u79fb\u690d\u556e\u9f7f\u7c7bNSPCs\u7597\u6548\u6709\u9650\uff0c\u672a\u6765\u9700\u63a2\u7d22<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8054\u5408\u7b56\u7565<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff08\u5982\u6297\u7622\u75d5\u6cbb\u7597\u6216\u795e\u7ecf\u8425\u517b\u652f\u6301\uff09\u4ee5\u7a81\u7834\u5fae\u73af\u5883\u9650\u5236\uff0c\u540c\u65f6\u4f18\u5148\u53d1\u5c55\u810a\u9ad3\u7279\u5316\u578bNSPCs\u79fb\u690d\u65b9\u6848\u3002<\/span><\/span><\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E4%BF%9D%E6%8A%A4%E4%B8%8E%E5%88%86%E5%8C%96%E5%9B%A0%E5%AD%90\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u795e\u7ecf\u4fdd\u62a4\u4e0e\u5206\u5316\u56e0\u5b50<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e3a\u4f18\u5316SCI\u73af\u5883\uff0c\u7814\u7a76\u8005\u4f7f\u7528\u4e86\u591a\u79cd\u795e\u7ecf\u4fdd\u62a4\u4e0e\u5206\u5316\u56e0\u5b50\u4f5c\u4e3a\u8f85\u52a9\u6cbb\u7597\uff0c\u53d1\u6325\u4fc3\u8fdb\u7ec6\u80de\u5b58\u6d3b\u3001\u5206\u5316\u3001\u8f74\u7a81\u751f\u957f\u3001\u7a81\u89e6\u4e0e\u9ad3\u9798\u5f62\u6210\u4ee5\u53ca\u8c03\u8282\u708e\u75c7\u7b49\u4f5c\u7528\u3002\u591a\u6570\u7814\u7a76\u5728\u4e9a\u6025\u6027SCI\u9636\u6bb5\u8fdb\u884c\uff0c\u5176\u5728\u6162\u6027SCI\u4e2d\u7684\u9002\u7528\u6027\u4ecd\u5f85\u63a2\u7d22\u3002\u5176\u4e2d\uff0c\u795e\u7ecf\u8425\u517b\u56e0\u5b503\uff08NT-3\uff09\u7684\u4f5c\u7528\u5728\u6162\u6027SCI\u4e2d\u6709\u6240\u7814\u7a76\u3002\u6539\u826f\u7684\u4eba\u6e90NT-3\uff08NT-3\/D15A\uff09\u53ef\u7ed3\u5408\u5e76\u6fc0\u6d3bTrkB\u548cTrkC\u53d7\u4f53\uff0c\u901a\u8fc7\u795e\u7ecf\u8425\u517b\u4fe1\u53f7\u4fc3\u8fdb\u7ec6\u80de\u5b58\u6d3b\u3001\u589e\u6b96\u53ca\u8f74\u7a81\u9ad3\u9798\u5316\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e00\u9879\u7814\u7a76\u8bc1\u5b9e\uff0c\u79fb\u690d\u8868\u8fbe\u7a81\u53d8\u578bNT-3\/D15A\u7684NSPCs\u53ef\u589e\u5f3a\u9ad3\u9798\u5f62\u6210\uff0c\u5e76\u5728\u6162\u6027\u671f\u4fc3\u8fdb\u90e8\u5206\u540e\u80a2\u529f\u80fd\u6062\u590d\u3002\u4f46\u8be5\u5b9e\u9a8c\u4e2d\u7684\u7ec6\u80de\u5b58\u6d3b\u7387\u4ecd\u7136\u5f88\u4f4e\uff0c\u4e14\u672a\u80fd\u586b\u5145\u635f\u4f24\u533a\u57df\u3002\u79fb\u690d\u7ec6\u80de\u6765\u6e90\u7684\u518d\u9ad3\u9798\u5316\u529f\u80fd\u4ecd\u9700\u901a\u8fc7\u7535\u751f\u7406\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u3002\u6b64\u5916\uff0c\u8be5\u7814\u7a76\u4ec5\u91c7\u7528BBB\u8bc4\u5206\u4f5c\u4e3a\u8fd0\u52a8\u529f\u80fd\u6307\u6807\uff0c\u672a\u80fd\u5168\u9762\u53cd\u6620\u8fd0\u52a8\u529f\u80fd\u6539\u5584\u60c5\u51b5\u3002<\/span><\/span><\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%BA%B7%E5%A4%8D%E6%96%B9%E6%B3%95\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5eb7\u590d\u65b9\u6cd5<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u9664\u8054\u5408\u751f\u5316\u5e72\u9884\u5916\uff0c<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5eb7\u590d\u8bad\u7ec3\u53ef\u9a71\u52a8\u4fdd\u7559\u7684\u795e\u7ecf\u73af\u8def\u53ef\u5851\u6027\uff0c\u4fc3\u8fdb\u8f74\u7a81\u840c\u53d1\uff0c\u4ece\u800c\u6062\u590d\u529f\u80fd<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u3002 NSPC\u79fb\u690d\u8054\u5408\u8dd1\u53f0\u8bad\u7ec3\u8fdb\u4e00\u6b65\u4fc3\u8fdb\u4e86\u795e\u7ecf\u5143\u5206\u5316\uff0c\u6539\u5584\u4e86\u810a\u9ad3\u4f20\u5bfc\u6027\u3001\u4e2d\u67a2\u6a21\u5f0f\u53d1\u751f\u5668\u6d3b\u6027\u548c\u8425\u517b\u652f\u6301\uff0c\u663e\u7740\u4fc3\u8fdb\u4e86\u8fd0\u52a8\u6062\u590d\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5728\u9888\u9ad3SCI\u6a21\u578b\u4e2d\uff0c\u524d\u80a2\u529f\u80fd\u8bad\u7ec3\u4e5f\u83b7\u5f97\u4e86\u7c7b\u4f3c\u7597\u6548\u3002\u5728\u4e25\u91cd\u53cc\u4fa7\u9888\u690e\u632b\u4f24\u540e1\u4e2a\u6708\u8fdb\u884c\u5eb7\u590d\u4e0e\u79fb\u690d\u8054\u5408\u6cbb\u7597\uff0c\u53ef\u663e\u7740\u6062\u590d\u524d\u80a2\u6293\u63e1\u529f\u80fd\uff0c\u5e76\u589e\u5f3a\u635f\u4f24\u533a\u5bbf\u4e3b\u76ae\u8d28\u810a\u9ad3\u8f74\u7a81\u7684\u518d\u751f\u3002\u9664\u6539\u5584\u8fd0\u52a8\u529f\u80fd\u5916\uff0c\u7ec6\u80de\u79fb\u690d\u7597\u6cd5\u8fd8\u6539\u5584\u4e86\u6162\u6027SCI\u4e2a\u4f53\u7684\u611f\u89c9\u529f\u80fd\u969c\u788d\u3002\u7c7b\u4f3c\u5730\uff0c\u8dd1\u53f0\u8bad\u7ec3\u8054\u5408NSPC\u79fb\u690d\u53ef\u51cf\u8f7b\u75db\u89c9\u76f8\u5173\u884c\u4e3a\u8868\u73b0\uff0c\u5982\u70ed\u6027\u5f02\u5e38\u75db\u548c\u7c97\u89e6-\u538b\u529b\u6027\u75db\u89c9\u8fc7\u654f\u660e\u663e\u7f13\u89e3\uff0c\u4f46\u5bf9\u7ec6\u89e6-\u538b\u529b\u6027\u75db\u89c9\u8fc7\u654f\u65e0\u663e\u7740\u5f71\u54cd\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7efc\u4e0a\u7814\u7a76\u8868\u660e\uff0c<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u556e\u9f7f\u7c7bNSPC\u79fb\u690d\u8054\u5408ChABC\u6539\u5584\u5fae\u73af\u5883\u3001\u795e\u7ecf\u8425\u517b\u56e0\u5b50\u4ee5\u53ca\u5eb7\u590d\u8bad\u7ec3\uff0c\u53ef\u4fc3\u8fdb\u6162\u6027SCI\u7684\u8fd0\u52a8\u529f\u80fd\u6062\u590d\uff0c\u800c\u5355\u72ec\u79fb\u690d\u556e\u9f7f\u7c7bNSPCs\u5e76\u4e0d\u80fd\u663e\u7740\u6539\u5584\u8fd0\u52a8\u529f\u80fd<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u3002\u4f46\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5373\u4f7f\u4ec5\u79fb\u690d\u556e\u9f7f\u7c7bNSPCs\uff0c\u4e5f\u80fd\u5728\u6162\u6027SCI\u635f\u4f24\u533a\u57df\u8bf1\u5bfc\u5e76\u652f\u6301\u7ec4\u7ec7\u5b66\u5c42\u9762\u7684\u518d\u751f\u3002\u76f8\u5173\u5b9e\u9a8c\u7814\u7a76\u7ed3\u679c\u89c1\u88681\u3002<\/span><\/span><\/p>\n<p id=\"tspara0010\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u88681 .\u556e\u9f7f\u52a8\u7269\u795e\u7ecf\u5e72\/\u7956\u7ec6\u80de\uff08NSPC\uff09\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u7684\u5b9e\u9a8c\u7814\u7a76\u3002<\/span><\/span><\/p>\n<figure class=\"wp-block-table is-style-stripes\" style=\"font-size: 13px;\">\n<table class=\"has-fixed-layout\">\n<thead>\n<tr>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53c2\u8003<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6807\u9898<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7ec6\u80de\u6765\u6e90<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6a21\u578b<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7ec6\u80de\u79fb\u690d\u65f6\u95f4<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u79fb\u690d\u90e8\u4f4d<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8054\u5408\u6cbb\u7597<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u89c2\u5bdf\u671f<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u884c\u4e3a\u6d4b\u8bd5<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e3b\u8981\u6210\u679c<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th colspan=\"10\"><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u556e\u9f7f\u7c7b\u6210\u5e74\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u884d\u751f\u7684NSPC<\/span><\/span><\/strong><\/th>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Karimi-Abdolrezaee\u7b49\u4eba\uff0c2006 <\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">26<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6210\u4eba\u795e\u7ecf\u524d\u4f53\u7ec6\u80de\u5ef6\u8fdf\u79fb\u690d\u4fc3\u8fdb\u810a\u9ad3\u635f\u4f24\u540e\u9ad3\u9798\u518d\u751f\u548c\u795e\u7ecf\u529f\u80fd\u6062\u590d<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c0f\u9f20\u6210\u5e74\u8111\u6e90\u6027NPC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5927\u9f20\uff0cT7 \u5939\u538b\u7f29<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u611f\u67d3\u540e8\u5468\uff08\u6162\u6027\u671f\uff09<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u611f\u67d3\u540e2 \u5468\uff08\u4e9a\u6025\u6027\u671f\uff09<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53cc\u4fa7\u635f\u4f24\u90e8\u4f4d\u524d\u7aef2\u6beb\u7c73\u548c\u5c3e\u7aef2\u6beb\u7c73\u5904<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7c73\u8bfa\u73af\u7d20\u6cbb\u7597\uff0c<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">GFs\uff1aPDGF-AA\u3001bFGF\u3001EGF<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6\u20138wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">BBB\u7f51\u683c\u6b65\u884c<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8db3\u8ff9\u5206\u6790<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6162\u6027\u810a\u9ad3\u635f\u4f24\u4e2d\u7ec6\u80de\u5b58\u6d3b\u7387\u4f4e<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Pfeifer\u7b49\u4eba\uff0c2006 <\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">27<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u81ea\u4f53\u6210\u5e74\u556e\u9f7f\u52a8\u7269\u795e\u7ecf\u7956\u7ec6\u80de\u79fb\u690d\u662f\u4fc3\u8fdb\u6162\u6027\u635f\u4f24\u810a\u9ad3\u7ed3\u6784\u4fee\u590d\u7684\u53ef\u884c\u7b56\u7565<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u81ea\u4f53\u5927\u9f20\u6210\u5e74\u8111\u6e90\u6027NPC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5927\u9f20\uff0cC3 \u80cc\u4fa7\u76ae\u8d28\u810a\u9ad3\u675f\u6a2a\u65ad<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">8\u5468\/\u5e74<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u635f\u4f24\u4e2d\u5fc3\u533a<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6210\u7ea4\u7ef4\u7ec6\u80de<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4fc3\u8fdb\u79fb\u690d\u7269\u5b58\u6d3b\u3001\u7ec4\u7ec7\u66ff\u6362\u548c\u8f74\u7a81\u518d\u751f<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Karimi-Abdolrezaee\u7b49\u4eba\uff0c2010\u00a0 <\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">38<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u79fb\u690d\u6210\u4eba\u795e\u7ecf\u5e72\u7ec6\u80de\/\u7956\u7ec6\u80de\u3001\u8f6f\u9aa8\u7d20\u9176\u548c\u751f\u957f\u56e0\u5b50\u7684\u534f\u540c\u4f5c\u7528\u4fc3\u8fdb\u6162\u6027\u635f\u4f24\u810a\u9ad3\u7684\u529f\u80fd\u4fee\u590d\u548c\u53ef\u5851\u6027<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c0f\u9f20\u6210\u5e74\u524d\u8111\u6765\u6e90\u7684NPC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5927\u9f20\uff0cT7 \u5939\u538b\u7f29<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">7\u5468<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53cc\u4fa7\u635f\u4f24\u90e8\u4f4d\u524d\u7aef2\u6beb\u7c73\u548c\u5c3e\u7aef2\u6beb\u7c73\u5904<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ChABC <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">GF\uff1aPDGF-AA\u3001bFGF \u548c EGF<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">9wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">BBB<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7f51\u683c\u884c\u8d70\u5206\u6790von Frey<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u70ed\u5f02\u5e38\u6027\u75bc\u75db<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4fc3\u8fdb\u76ae\u8d28\u810a\u9ad3\u675f\u7684\u8f74\u7a81\u5b8c\u6574\u6027\u548c\u53ef\u5851\u6027\uff0c\u589e\u5f3a\u4e0b\u884c\u8840\u6e05\u7d20\u901a\u8def\u7684\u53ef\u5851\u6027<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<th colspan=\"10\"><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u556e\u9f7f\u52a8\u7269\u80da\u80ce\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u884d\u751f\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/span><\/span><\/strong><\/th>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Nishimura\u7b49\u4eba\uff0c2013\u00a0 <\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">14<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u635f\u4f24\u810a\u9ad3\u5fae\u73af\u5883\u7684\u65f6\u95f4\u4f9d\u8d56\u6027\u53d8\u5316\u5f71\u54cd<\/span><\/span><span class=\"xintheme_tag_link\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24<\/span><\/span><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7684\u6f5c\u529b<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">E14\u5c0f\u9f20\u7eb9\u72b6\u4f53\u6765\u6e90\u7684NSPC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c0f\u9f20\uff0cT10\u632b\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">9dpi\uff08\u4e9a\u6025\u6027\u671f\uff09<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">7wpi\uff08\u6162\u6027\u671f\uff09<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u75c5\u53d8\u4e2d\u5fc3<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">BMS <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Rotarod \u6d4b\u8bd5<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6b65\u6001\u5206\u6790<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u57fa\u56e0\u7f16\u7801\u8868\u8fbe\u7684\u79fb\u690d\u7ec6\u80de\u5b58\u6d3b\u7387\u53ca\u5206\u5316\u8868\u578b\u65e0\u660e\u663e\u5dee\u5f02\u3002<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Kumamaru\u7b49\u4eba\uff0c2013\u00a0 <\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">28<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u79fb\u690d\u795e\u7ecf\u5e72\u7ec6\u80de\/\u524d\u4f53\u7ec6\u80de\u7684\u6cbb\u7597\u6d3b\u6027\u5728\u6162\u6027\u635f\u4f24\u810a\u9ad3\u4e2d\u5e76\u672a\u5904\u4e8e\u4f11\u7720\u72b6\u6001<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">E14\u5c0f\u9f20\u7eb9\u72b6\u4f53\u6765\u6e90\u7684NSPC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c0f\u9f20\uff0cT10\u4e2d\u5ea6\u632b\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">12\u5468\/\u5e74<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53cc\u4fa7\u635f\u4f24\u90e8\u4f4d\u524d\u7aef1\u6beb\u7c73\u548c\u5c3e\u7aef1\u6beb\u7c73\u5904<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6wpt\uff08RNA\u6d4b\u5e8f\uff1a1wpt\uff09<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">BMS\u3001<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7535\u7f51\u6b65\u6d4b\u3001<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8db3\u8ff9\u5206\u6790<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u79fb\u690d\u7684NSPC \u5206\u5316\u4e3a\u795e\u7ecf\u5143\/\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u5e76\u4ea7\u751f\u6cbb\u7597\u5206\u5b50\uff0c\u4f46\u5e76\u672a\u6539\u5584\u8fd0\u52a8\u529f\u80fd<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Dagci\u7b49\u4eba\uff0c2009\u00a0 <\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">34<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u80da\u80ce\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u6025\u6027\u548c\u6162\u6027\u810a\u9ad3\u635f\u4f24\u5927\u9f20\u5c3e\u90e8\u8131\u560c\u5464\/\u8131\u5627\u5576\u5185\u5207\u9176-1\/\u6c27\u5316\u8fd8\u539f\u56e0\u5b50-1\uff08APE\/ref-1\uff09\u8868\u8fbe\u53caDNA\u635f\u4f24\u7684\u53d8\u5316<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">E13.5\u5927\u9f20\u810a\u9ad3\u6765\u6e90\u7684NSC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5927\u9f20\uff0cT8\/9 \u9009\u62e9\u6027\u6d88\u878d\u4fa7\u767d\u8d28\u675f\u548c\u80cc\u90e8\u548c\u8179\u90e8\u7070\u8d28\u7684\u6781\u5c0f\u90e8\u5206<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u611f\u67d3\u540e4\u5468\uff08\u6162\u6027\u671f\uff09<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u611f\u67d3\u540e1 \u5468\uff08\u6025\u6027\u671f\uff09<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u635f\u4f24\u4e2d\u5fc3\u533a<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8840\u8111\u5c4f\u969c<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">DNA\u635f\u4f24\u6c34\u5e73\u964d\u4f4e<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Hayakawa\u7b49\u4eba\uff0c2022\u00a0 <\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">35<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c06\u795e\u7ecf\u7956\u7ec6\u80de\u79fb\u690d\u5230\u6162\u6027\u80cc\u67f1\u635f\u4f24\u6a21\u578b\u4e2d<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">E13.5\u5927\u9f20\u810a\u9ad3\u6765\u6e90\u7684NPC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5927\u9f20\uff0cC4\u5b8c\u5168\u6027\u5355\u4fa7\u80cc\u67f1\u635f\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4\u5468pi\uff1b6\u5468pi\uff1b12\u5468pi<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u635f\u4f24\u4e2d\u5fc3\u533a<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">3\u62165wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">NPC \u5b58\u6d3b\u5e76\u5206\u5316\u4e3a\u795e\u7ecf\u5143\uff0c\u4fc3\u8fdb\u5bbf\u4e3b\u611f\u89c9\u8f74\u7a81\u518d\u751f\uff0c\u4fee\u9970\u795e\u7ecf\u80f6\u8d28\/\u7ea4\u7ef4\u5316\u75a4\u75d5<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<h2><span class=\"ez-toc-section\" id=\"%E4%BA%BA%E7%B1%BB%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%A5%96%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E7%9A%84%E8%BF%9B%E7%A8%8B\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7b\u795e\u7ecf\u5e72\/\u7956\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u8fdb\u7a0b<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u867d\u7136\u556e\u9f7f\u7c7b\u52a8\u7269NSPCs\u79fb\u690d\u5728\u6162\u6027SCI\u52a8\u7269\u6a21\u578b\u4e2d\u663e\u793a\u51fa\u826f\u597d\u7684\u524d\u666f\u548c\u6709\u76ca\u7684\u7ed3\u679c\uff0c\u4f46\u7531\u4e8e\u5f02\u79cd\u79fb\u690d\u7684\u539f\u56e0\uff0c\u8fd9\u4e9b\u7ec6\u80de\u4e0d\u80fd\u76f4\u63a5\u7528\u4e8e\u6cbb\u7597\u4eba\u7c7bSCI\u3002\u56e0\u6b64\uff0c\u7814\u7a76\u4ebaNSPCs\uff08hNSPCs\uff09\u5728\u6162\u6027SCI\u6a21\u578b\u4e2d\u7684\u7597\u6548\u5177\u6709\u975e\u5e38\u91cd\u8981\u7684\u73b0\u5b9e\u610f\u4e49\u3002\u4ee5\u524d\uff0chNSPCs\u7684\u4e3b\u8981\u6765\u6e90\u662f\u6d41\u4ea7\u7684\u80ce\u513f\u3002\u7531\u4e8e\u83b7\u53d6hESCs\u5b58\u5728\u4f26\u7406\u95ee\u9898\uff0chiPSCs\u7684\u51fa\u73b0\u53ef\u751f\u6210\u4efb\u4f55\u7279\u5b9a\u7c7b\u578b\u7684\u7ec6\u80de\uff0c\u5e76\u4f7f\u81ea\u4f53\u79fb\u690d\u65e0\u514d\u75ab\u6392\u65a5\u53cd\u5e94\u6210\u4e3a\u53ef\u80fd\u3002<\/span><\/span><\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"HuCNS-SC%E7%BB%86%E8%83%9E%E7%B3%BB%E7%9A%84%E7%96%97%E6%95%88%E5%B1%80%E9%99%90%E4%B8%8E%E4%B8%B4%E5%BA%8A%E6%8C%91%E6%88%98\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">HuCNS-SC\u7ec6\u80de\u7cfb\u7684\u7597\u6548\u5c40\u9650\u4e0e\u4e34\u5e8a\u6311\u6218<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u80ce\u8111\u6e90\u6027\u795e\u7ecf\u5e72\u7ec6\u80de\uff08HuCNS-SC\uff09\u5206\u4e3a\u7814\u7a76\u7ec6\u80de\u7cfb\uff08RCL\uff09\u548c\u4e34\u5e8a\u7ec6\u80de\u7cfb\u3002\u5728<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6162\u6027\u80f8\u9ad3\u635f\u4f24<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u556e\u9f7f\u6a21\u578b\u4e2d<\/span><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff0cHuCNS-SC RCL\u79fb\u690d\u540e\u5b58\u6d3b\u5206\u5316\uff0c\u4e3b\u8981\u5f62\u6210\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u548c\u795e\u7ecf\u5143\uff0c\u5e76\u6539\u5584\u8fd0\u52a8\u534f\u8c03\u6027\uff0c\u4f46<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7f3a\u4e4f\u5173\u952e\u7ec4\u7ec7\u5b66\u8bc1\u636e<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff08\u5982\u635f\u4f24\u4f53\u79ef\u7f29\u5c0f\u3001\u8f74\u7a81\u518d\u751f\u6216\u7a81\u89e6\u5f62\u6210\uff09\uff0c\u4e14\u672a\u51cf\u5c11\u80f6\u8d28\u7622\u75d5\u3002<\/span><\/span><\/p>\n<p>\u5176\u7814\u7a76\u591a\u4f9d\u8d56<strong>\u514d\u75ab\u7f3a\u9677\u52a8\u7269\u6a21\u578b<\/strong>\uff0c\u4e34\u5e8a\u53ef\u63a8\u5e7f\u6027\u5b58\u7591\u3002\u66f4\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5728<strong>\u9888\u9ad3\u635f\u4f24<\/strong>\u4e2d\u7597\u6548\u663e\u8457\u53d7\u9650\uff1aRCL\u4ec5\u4e9a\u6025\u6027\u671f\u6709\u6548\uff0c\u4e34\u5e8a\u7ec6\u80de\u7cfb\u5728\u6162\u6027\u671f\u5b8c\u5168\u65e0\u6548\uff0c\u51f8\u663e\u5176<strong>\u65f6\u95f4\u7a97\u4e0e\u635f\u4f24\u90e8\u4f4d\u7684\u53cc\u91cd\u5c40\u9650\u6027<\/strong>\u3002\u672a\u6765\u9700\u5f00\u53d1\u9488\u5bf9\u5ef6\u8fdf\u6162\u6027\u671f\u7684\u4f18\u5316\u7b56\u7565\u4ee5\u63d0\u5347\u4e34\u5e8a\u4ef7\u503c\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"hiPSC%E8%A1%8D%E7%94%9F%E7%A5%9E%E7%BB%8F%E5%89%8D%E4%BD%93%E7%BB%86%E8%83%9E%E7%9A%84%E6%B2%BB%E7%96%97%E8%BD%AC%E5%90%91\"><\/span><strong>hiPSC\u884d\u751f\u795e\u7ecf\u524d\u4f53\u7ec6\u80de\u7684\u6cbb\u7597\u8f6c\u5411<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u5728\u6162\u6027\u9888\u9ad3\u635f\u4f24\u6a21\u578b\u4e2d\uff0c<strong>\u5c3e\u4fa7\u5316hiPSC\u884d\u751f\u7684\u795e\u7ecf\u524d\u4f53\u7ec6\u80de\uff08NPCs\uff09<\/strong>\u00a0\u53ef\u5206\u5316\u4e3a\u795e\u7ecf\u5143\u548c\u80f6\u8d28\u7ec6\u80de\uff0c\u5374\u672a\u80fd\u663e\u8457\u6062\u590d\u529f\u80fd\u2014\u2014\u8fd9\u53ef\u80fd\u4e0e<strong>\u624b\u529f\u80fd\u6062\u590d\u9700\u66f4\u5f3a\u4e0b\u884c\u8f93\u5165<\/strong>\u7684\u7279\u6027\u76f8\u5173\u3002\u5b89\u5168\u6027\u65b9\u9762\uff0c\u79fb\u690d\u540e\u672a\u89c1\u80bf\u7624\u751f\u957f\u6216\u75db\u89c9\u5f02\u5e38\uff0c\u4f46\u7597\u6548\u4e89\u8bae\u663e\u8457\uff1a<strong>\u539f\u4f4d\u79fb\u690d\u81f3\u635f\u4f24\u6838\u5fc3\u533a\u6548\u679c\u6709\u9650<\/strong>\uff0c\u800c\u8fdc\u7aef\u6ce8\u5c04\u867d\u6709\u6539\u5584\u5374\u6613\u538b\u8feb\u6b63\u5e38\u810a\u9ad3\u3002<\/p>\n<p>\u56e0\u6b64\uff0c\u7814\u7a76\u7126\u70b9\u5df2\u4ece\u5355\u72ec\u79fb\u690d\u8f6c\u5411<strong>\u8054\u5408\u6cbb\u7597<\/strong>\uff1a\u7ed3\u5408\u4fc3\u5206\u5316\u5c0f\u5206\u5b50\u836f\u7269\u3001\u5eb7\u590d\u8bad\u7ec3\/\u7535\u523a\u6fc0\u6216\u5fae\u73af\u5883\u6539\u826f\u6750\u6599\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5f53\u524d\u8054\u5408\u7b56\u7565<strong>\u4f18\u5148\u9009\u7528hiPSC-NPCs<\/strong>\uff0c\u51f8\u663e\u5176\u5728\u672a\u6765\u4e34\u5e8a\u8f6c\u5316\u4e2d\u7684\u72ec\u7279\u6f5c\u529b\u3002<\/p>\n<p>\u91cd\u8981\u7684\u662f\uff0c\u6700\u8fd1\u53d1\u73b0\uff0c\u5728\u6162\u6027SCI\u6a21\u578b\u4e2d\u5355\u72ec\u79fb\u690dhiPSC\u884d\u751f\u7684\u795e\u7ecf\u4e0a\u76ae\u6837\u5e72\u7ec6\u80de\u53ef\u4ee5\u9006\u8f6c\u810a\u9ad3\u7a7a\u6d1e\u5e76\u6539\u5584\u708e\u75c7\u73af\u5883\uff0c\u8fd9\u53ef\u80fd\u8868\u660e\u6765\u81ea\u4e0d\u540c\u6765\u6e90\u7684hNSPC\u5177\u6709\u66f4\u5927\u7684\u6cbb\u7597\u6f5c\u529b\uff0c\u5c3d\u7ba1\u662f\u5728SCI\u7684\u6162\u6027\u671f\u5355\u72ec\u79fb\u690d\u3002\u7eb3\u5165\u7684\u5173\u4e8e\u6162\u6027SCI\u7684hNSPC\u79fb\u690d\u4e34\u5e8a\u524d\u7814\u7a76\u7684\u7279\u5f81\u5982\u88682\u6240\u793a\u3002<\/p>\n<p id=\"tspara0020\">\u8868 2\u00a0.\u4eba\u7c7bNSPC\u79fb\u690d\u6cbb\u7597\u6162\u6027SCI\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u3002<\/p>\n<figure class=\"wp-block-table is-style-stripes\" style=\"font-size: 13px;\">\n<table class=\"has-fixed-layout\">\n<thead>\n<tr>\n<th>\u4f5c\u8005\uff0c\u5e74\u4efd<\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6807\u9898<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7ec6\u80de\u6765\u6e90<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6a21\u578b<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7ec6\u80de\u79fb\u690d\u65f6\u95f4<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u79fb\u690d\u90e8\u4f4d<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8054\u5408\u6cbb\u7597<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u89c2\u5bdf\u671f<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u884c\u4e3a\u6d4b\u8bd5<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e3b\u8981\u6210\u679c<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th colspan=\"10\"><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u80ce\u8111\u6765\u6e90\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/span><\/span><\/strong><\/th>\n<\/tr>\n<tr>\n<td>Cheng\u7b49\u4eba\uff0c2017<sup>13<\/sup><\/td>\n<td>\u810a\u9ad3\u635f\u4f24\u540e<span class=\"xintheme_tag_link\">\u0632\u0631\u0627\u0639\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629<\/span>\u7684\u65f6\u673a\u662f\u5426\u4f1a\u5f71\u54cd\u52a8\u7269\u6a21\u578b\u7684\u7ed3\u679c<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u80ce\u8111\u6765\u6e90\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/span><\/span><\/td>\n<td>\u5927\u9f20\uff0c\u4e2d\u5ea6\u632b\u4f24<\/td>\n<td>\u611f\u67d3\u540e1\u5468\uff08\u4e9a\u6025\u6027\u671f\uff09<br \/>\n\u611f\u67d3\u540e4 \u5468\uff08\u6162\u6027\u671f\uff09<br \/>\n\u611f\u67d3\u540e0 \u5468\uff08\u6025\u6027\u671f\uff09<\/td>\n<td>\u4f4d\u4e8e\u75c5\u53d8\u90e8\u4f4d\u8fdc\u7aef<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8840\u8111\u5c4f\u969c<\/span><\/span><\/td>\n<td>\u4e09\u4e2a\u65f6\u95f4\u7ec4\u5747\u51fa\u73b0\u529f\u80fd\u6539\u5584\uff0c\u4f46\u4e9a\u6025\u6027\u79fb\u690d\u6700\u6709\u6548<\/td>\n<\/tr>\n<tr>\n<td>Salazar\u7b49\u4eba\uff0c2010<sup>19<\/sup><\/td>\n<td>\u4eba\u7c7b\u795e\u7ecf\u5e72\u7ec6\u80de\u5728\u65e9\u671f\u6162\u6027\u810a\u9ad3\u635f\u4f24 NOD-scid \u5c0f\u9f20\u6a21\u578b\u4e2d\u5206\u5316\u5e76\u4fc3\u8fdb\u8fd0\u52a8\u6062\u590d<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u80ce\u8111\u6765\u6e90\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c0f\u9f20\uff0cT10\u632b\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">30dpi<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u635f\u4f24\u4e2d\u5fc3\u7684\u524d\u7aef\u548c\u5c3e\u90e8<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">16wpt<\/span><\/span><\/td>\n<td>BMS<br \/>\nCatWalk \u6b65\u6001\u5206\u6790<br \/>\nVon Frey<\/td>\n<td>\u6539\u5584\u8fd0\u52a8\u6062\u590d<\/td>\n<\/tr>\n<tr>\n<td>Anderson\u7b49\u4eba\uff0c2017<sup>53<\/sup><\/td>\n<td>\u4eba\u7c7b\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u5e72\u7ec6\u80de\u7528\u4e8e\u9888\u810a\u9ad3\u635f\u4f24\u901a\u8def\u7814\u7a76\u7684\u4e34\u5e8a\u524d\u7597\u6548\u5931\u8d25<\/td>\n<td>HuCNS-SCs \u7684 CCL \u6216 RCL<\/td>\n<td>\u5c0f\u9f20\uff0cC5\u5355\u4fa7\u632b\u4f24<\/td>\n<td>60dpi\uff08\u6162\u6027\u671f\uff09<br \/>\n9dpi\uff08\u4e9a\u6025\u6027\u671f\uff09<\/td>\n<td>\u8ddd\u4e2d\u7ebf 0.75\u6beb\u7c73\u5904\u8fdb\u884c\u4e24\u6b21\u5599\u90e8\u6ce8\u5c04\u548c\u4e24\u6b21\u5c3e\u90e8\u6ce8\u5c04<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">12wpt<\/span><\/span><\/td>\n<td>\u5706\u67f1\u4efb\u52a1<br \/>\n\u524d\u722a\u63e1\u529b \u68af\u6881<br \/>\n\u732b\u6b65\u5206\u6790<br \/>\n\u51af\u00b7\u5f17\u96f7\u8bd5\u9a8c<br \/>\n\u54c8\u683c\u91cc\u592b\u65af\u8bd5\u9a8c<\/td>\n<td>HuCNS-SC \u7684 RCL \u5728\u79fb\u690d 9dpi \u65f6\u6709\u6548\uff0c\u4f46\u5728 60dpi \u65f6\u65e0\u6548\uff0c\u800c HuCNS-SC \u7684 CCL \u5728\u9888\u690e SCI \u6a21\u578b\u4e2d\u65e0\u6548<\/td>\n<\/tr>\n<tr>\n<td>Piltti\u7b49\u4eba\uff0c2013<sup>56<\/sup><\/td>\n<td>\u4eba\u7c7b\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684\u5b89\u5168\u6027<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u80ce\u8111\u6765\u6e90\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/span><\/span><\/td>\n<td>\u5927\u9f20\uff0cT10\u4e2d\u5ea6\u632b\u4f24<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">60dpi\uff08\u6162\u6027\u671f\uff09<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">9dpi\uff08\u4e9a\u6025\u6027\u671f\uff09<\/span><\/span><\/td>\n<td>\u5728T7\/T8 \u5904\u8fdb\u884c\u4e24\u6b21\u53cc\u4fa7\u5599\u90e8\u6ce8\u5c04\uff0c\u5728 T10\/T11 \u5904\u8fdb\u884c\u53e6\u5916\u4e24\u6b21\u5c3e\u90e8\u6ce8\u5c04<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">14wpt<\/span><\/span><\/td>\n<td>BBB von Frey<br \/>\nHargreaves<br \/>\nCatWalk \u6b65\u6001\u5206\u6790<\/td>\n<td>\u79fb\u690d\u65f6\u673a\u4e0d\u4f1a\u5f15\u8d77\u5f02\u5e38\u6027\u75bc\u75db\u6216\u75db\u89c9\u8fc7\u654f\u6307\u6807\u7684\u53d8\u5316\uff0c\u652f\u6301 hCNS-SCns \u79fb\u690d\u5728\u6162\u6027 SCI \u4e2d\u7684\u5b89\u5168\u6027\u3002<\/td>\n<\/tr>\n<tr>\n<td>Nekanti\u7b49\u4eba\uff0c2024<sup>62<\/sup><\/td>\n<td>\u591a\u901a\u9053\u6865\u548c NSC \u534f\u540c\u4f5c\u7528\uff0c\u589e\u5f3a\u8f74\u7a81\u518d\u751f\u3001\u9ad3\u9798\u5f62\u6210\u3001\u7a81\u89e6\u91cd\u65b0\u8fde\u63a5\u548c SCI \u540e\u7684\u6062\u590d<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u80ce\u8111\u6765\u6e90\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/span><\/span><\/td>\n<td>\u5c0f\u9f20\uff0cC5\u534a\u5207\u672f<\/td>\n<td>4\u5468PI<\/td>\n<td>\u4fdd\u7559\u7684\u810a\u9ad3\u5b9e\u8d28\uff1a\u75c5\u53d8\u524d\u7aef\u4e24\u4e2a\uff0c\u75c5\u53d8\u5c3e\u7aef\u4e24\u4e2a<\/td>\n<td>PLG\u652f\u67b6\uff08\u690d\u51650dpi\uff09<\/td>\n<td>16wpt\uff08\u8ddf\u8e2a26wpt\uff09<\/td>\n<td>\u6c34\u5e73\u68af\u6881\u732b\u6b65\u6b65\u6001\u5206\u6790<\/td>\n<td>\u810a\u9ad3\u635f\u4f24\u540e\u8f74\u7a81\u518d\u751f\u3001\u9ad3\u9798\u5f62\u6210\u3001\u7a81\u89e6\u91cd\u65b0\u8fde\u63a5\u548c\u8fd0\u52a8\u6062\u590d\u589e\u5f3a<\/td>\n<\/tr>\n<tr>\n<td colspan=\"10\"><strong>hESC\u884d\u751f\u7684NPC<\/strong><\/td>\n<\/tr>\n<tr>\n<td>Jones\u7b49\u4eba\uff0c2021<sup>51<\/sup><\/td>\n<td>\u4eba\u7c7b\u80da\u80ce\u5e72\u7ec6\u80de\u884d\u751f\u7684\u795e\u7ecf\u5d74\u7ec6\u80de\u4fc3\u8fdb\u6210\u5e74\u5927\u9f20\u810a\u9ad3\u635f\u4f24\u540e\u53d1\u82bd\u548c\u8fd0\u52a8\u6062\u590d<\/td>\n<td>\u4eba\u80da\u80ce\u5e72\u7ec6\u80de-\u795e\u7ecf\u7956\u7ec6\u80de<\/td>\n<td>\u5927\u9f20\uff0cC3\/4 \u4fa7\u7d22\u548c\u90bb\u8fd1\u7070\u8d28\u88ab\u6a2a\u65ad<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">7\u5468<\/span><\/span><\/td>\n<td>\u8ddd\u75c5\u53d8\u90e8\u4f4d\u524d\u7aef\u548c\u5c3e\u7aef1\u6beb\u7c73<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">16wpt<\/span><\/span><\/td>\n<td>\u5782\u76f4\u5706\u67f1\u4f53\u8bd5\u9a8c<\/td>\n<td>\u4fc3\u8fdb\u4e0b\u884c\u7f1d\u810a\u9ad3\u6295\u5c04\u7684\u91cd\u5851\u548c\u524d\u80a2\u8fd0\u52a8\u6062\u590d<\/td>\n<\/tr>\n<tr>\n<th colspan=\"10\"><strong>hiPSC\u884d\u751f\u7684NSPC<\/strong><\/th>\n<\/tr>\n<tr>\n<td>Nutt\u7b49\u4eba\uff0c2013<sup>54<\/sup><\/td>\n<td>\u5c3e\u90e8\u4eba\u7c7b iPSC \u884d\u751f\u7684\u795e\u7ecf\u7956\u7ec6\u80de\u53ef\u4ea7\u751f\u795e\u7ecf\u5143\u548c\u795e\u7ecf\u80f6\u8d28\u7ec6\u80de\uff0c\u4f46\u5728\u65e9\u671f\u6162\u6027\u810a\u9ad3\u635f\u4f24\u6a21\u578b\u4e2d\u65e0\u6cd5\u6062\u590d\u529f\u80fd<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">hiPSC-NSC<\/span><\/span><\/td>\n<td>\u5927\u9f20\uff0cC4\u5355\u4fa7\u632b\u4f24<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4\u5468PI<\/span><\/span><\/td>\n<td>\u4e00\u4e2a\u4f4d\u4e8e\u53d7\u4f24\u90e8\u4f4d\u7684\u524d\u7aef\uff0c\u4e00\u4e2a\u4f4d\u4e8e\u53d7\u4f24\u90e8\u4f4d\u7684\u5c3e\u7aef<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">8wpt<\/span><\/span><\/td>\n<td>\u80a2\u4f53\u4f7f\u7528\u4e0d\u5bf9\u79f0\u6d4b\u8bd5<br \/>\n\u524d\u80a2\u4f38\u624b\u4efb\u52a1<br \/>\n\u51af\u00b7\u5f17\u96f7<\/td>\n<td>\u5206\u5316\u4e3a\u795e\u7ecf\u5143\u548c\u795e\u7ecf\u80f6\u8d28\u7ec6\u80de\uff0c\u4f46\u672a\u80fd\u6062\u590d\u529f\u80fd<\/td>\n<\/tr>\n<tr>\n<td>Cheng\u7b49\u4eba\uff0c2016<sup>57<\/sup><\/td>\n<td>\u6162\u6027\u810a\u9ad3\u635f\u4f24\u540e\u4eba\u7c7b\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u5c40\u90e8\u4e0e\u8fdc\u7aef\u79fb\u690d<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">hiPSC-NSC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5927\u9f20\uff0cT10\u4e2d\u5ea6\u632b\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4\u5468PI<\/span><\/span><\/td>\n<td>\u75c5\u53d8\u90e8\u4f4d\u5c40\u90e8\u4e0e\u8fdc\u7aef<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8840\u8111\u5c4f\u969c<\/span><\/span><\/td>\n<td>\u4ec5\u8fdc\u7aef\u6ce8\u5c04\u8fbe\u5230\u7edf\u8ba1\u5b66\u4e0a\u663e\u8457\u7684\u529f\u80fd\u6539\u5584<\/td>\n<\/tr>\n<tr>\n<td>\u9a6c\u4e01-\u6d1b\u4f69\u65af\u7b49\u4eba\uff0c2021 \u5e74<sup>58<\/sup><\/td>\n<td>\u5efa\u7acb\u8001\u5e74\u5927\u9f20\u6162\u6027\u9888\u810a\u9ad3\u635f\u4f24\u6a21\u578b\u7528\u4e8e\u7ec6\u80de\u6cbb\u7597\u7814\u7a76<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">hiPSC-NPC<\/span><\/span><\/td>\n<td>\u8001\u5e74\u5927\u9f20\uff0820\u6708\u9f84\uff09\uff0cC4\u534a\u4fa7\u632b\u4f24<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4\u5468PI<\/span><\/span><\/td>\n<td>\u632b\u4f24\u90e8\u4f4d\u7684\u524d\u7aef\u548c\u5c3e\u7aef<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4wpt<\/span><\/span><\/td>\n<td>\u524d\u80a2\u4f38\u5c55\u4efb\u52a1<br \/>\nBBB \u80a2\u4f53\u4f7f\u7528\u4e0d\u5bf9\u79f0\u6d4b\u8bd5<\/td>\n<td>\u6ce8\u5c04\u7684\u7ec6\u80de\u5b58\u6d3b\u4e0b\u6765\uff0c\u6ca1\u6709\u5f15\u53d1\u80bf\u7624\u3002\u8fd0\u52a8\u529f\u80fd\u6ca1\u6709\u6539\u5584<\/td>\n<\/tr>\n<tr>\n<td>Okubo\u7b49\u4eba\uff0c2018<sup>59<\/sup><\/td>\n<td>\u4f7f\u7528\u03b3-\u5206\u6ccc\u9176\u6291\u5236\u5242\u6cbb\u7597\u53ef\u4fc3\u8fdb\u4eba\u7c7biPSC\u884d\u751f\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684\u529f\u80fd\u6062\u590d<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">hiPSC-NSPC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c0f\u9f20\uff0cT10\u4e2d\u5ea6\u632b\u4f24<\/span><\/span><\/td>\n<td>6\u5468PI<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u635f\u4f24\u4e2d\u5fc3\u533a<\/span><\/span><\/td>\n<td>\u03b3-\u5206\u6ccc\u9176\u6291\u5236\u5242<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">12wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">BMS <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Rotarod \u6d4b\u8bd5<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6b65\u6001\u5206\u6790<\/span><\/span><\/td>\n<td>\u4fc3\u8fdb\u8f74\u7a81\u518d\u751f\u3001<br \/>\n\u9ad3\u9798\u518d\u751f\u3001\u6291\u5236\u4e0e\u5bbf\u4e3b\u795e\u7ecf\u56de\u8def\u7684\u7a81\u89e6\u5f62\u6210\u4ee5\u53ca\u7f51\u72b6\u810a\u9ad3\u675f\u7ea4\u7ef4\u5f62\u6210\uff0c\u6709\u52a9\u4e8e\u8fd0\u52a8\u529f\u80fd\u6062\u590d<\/td>\n<\/tr>\n<tr>\n<td>Ruzicka\u7b49\u4eba\uff0c2019<sup>60<\/sup><\/td>\n<td>\u5c06 iPS \u884d\u751f\u7684\u795e\u7ecf\u7956\u7ec6\u80de\u63a5\u79cd\u4e8e\u5177\u6709\u53cc\u91cd\u5b54\u9699\u5ea6\u7684\u5c42\u7c98\u8fde\u86cb\u767d\u6d82\u5c42 pHEMA-MOETACl \u6c34\u51dd\u80f6\u4e0a\uff0c\u5bf9\u6162\u6027\u810a\u9ad3\u635f\u4f24\u5927\u9f20\u6a21\u578b\u7684\u5f71\u54cd<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">hiPSC-NPC<\/span><\/span><\/td>\n<td>\u5927\u9f20\uff0cT8-9\u7403\u56ca\u538b\u8feb<\/td>\n<td>5\u5468PI<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u635f\u4f24\u4e2d\u5fc3\u533a<\/span><\/span><\/td>\n<td>\u5c42\u7c98\u8fde\u86cb\u767d\u6d82\u5c42\u7684pHEMA-MOETACl\u6c34\u51dd\u80f6<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">23wpt<\/span><\/span><\/td>\n<td>BBB<br \/>\n\u8db3\u5e95\u6d4b\u8bd5<\/td>\n<td>\u51cf\u5c11\u7a7a\u5316\u5e76\u652f\u6301\u7ec6\u80de\u5b58\u6d3b\uff0c\u4f46\u8fd0\u52a8\u6062\u590d\u6ca1\u6709\u663e\u8457\u6539\u5584\u3002<\/td>\n<\/tr>\n<tr>\n<td>Hashimoto\u7b49\u4eba\uff0c2023<sup>61<\/sup><\/td>\n<td>\u5fae\u73af\u5883\u8c03\u8282\u4e0e\u4eba\u7c7b\u5e72\u7ec6\u80de\u79fb\u690d\u534f\u540c\u4f5c\u7528\u53ef\u4fc3\u8fdb\u6162\u6027\u5b8c\u5168\u6027\u810a\u9ad3\u635f\u4f24\u540e\u7684\u529f\u80fd\u6062\u590d<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">hiPSC-NSPC<\/span><\/span><\/td>\n<td>\u88f8\u9f20\uff0cT10\u5b8c\u5168\u6a2a\u5207<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">7\u5468<\/span><\/span><\/td>\n<td>\u75c5\u53d8\u95f4\u9699<\/td>\n<td>\u809d\u7ec6\u80de\u751f\u957f\u56e0\u5b50\u91ca\u653e\u80bdPelnac G plus<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6wpt<\/span><\/span><\/td>\n<td>BBB\u6ccc\u5c3f\u529f\u80fd\u969c\u788d\u6062\u590d<\/td>\n<td>\u6539\u5584\u8fd0\u52a8\u548c\u6ccc\u5c3f\u529f\u80fd\uff1b\u5fae\u73af\u5883\u8c03\u8282\uff0c\u5305\u62ec\u6291\u5236\u708e\u75c7\u3001\u51cf\u5c11\u75a4\u75d5\u5f62\u6210\u548c\u589e\u5f3a\u8840\u7ba1\u5316\uff0c<\/td>\n<\/tr>\n<tr>\n<td>Wertheim\u7b49\u4eba\uff0c2022<sup>63<\/sup><\/td>\n<td>\u5229\u7528\u5de5\u7a0b\u5316\u7684 iPSC \u884d\u751f\u7684 3D \u795e\u7ecf\u5143\u7f51\u7edc\u5728\u6162\u6027\u671f\u518d\u751f\u53d7\u635f\u810a\u9ad3<\/td>\n<td>iPSC\u884d\u751f\u76843D\u810a\u9ad3\u8fd0\u52a8\u795e\u7ecf\u5143\u7f51\u7edc<\/td>\n<td>\u5c0f\u9f20\uff0cT10 \u5de6\u534a\u5207<\/td>\n<td>6\u5468PI<\/td>\n<td>\u75c5\u7076\u8154<\/td>\n<td>\u624b\u672f\u75a4\u75d5\u53bb\u9664<br \/>\n\u7ec6\u80de\u5916\u57fa\u8d28\u6c34\u51dd\u80f6<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">8wpt<\/span><\/span><\/td>\n<td>\u8d70\u79c0\u6b65\u6001\u5206\u6790<br \/>\n\u7f51\u683c\u6b65\u6001<\/td>\n<td>\u57fa\u4e8e 3D \u52a8\u6001\u751f\u7269\u6750\u6599\u7684\u5fae\u73af\u5883\uff0c\u4e3a\u80da\u80ce\u53d1\u80b2\u7684\u4e0d\u540c\u9636\u6bb5\u63d0\u4f9b\u4e0d\u540c\u7684\u751f\u5316\u7ebf\u7d22\uff0c\u4fc3\u8fdb\u529f\u80fd\u6027\u810a\u9ad3\u690d\u5165\u7269\u7684\u7ec4\u88c5\uff0c\u4ece\u800c\u4fc3\u8fdb\u6162\u6027 SCI \u60a3\u8005\u690d\u5165\u540e\u7684\u529f\u80fd\u6027\u611f\u89c9\u8fd0\u52a8\u6062\u590d<\/td>\n<\/tr>\n<tr>\n<td>Patil\u7b49\u4eba\uff0c2023<sup>64<\/sup><\/td>\n<td>\u7535\u523a\u6fc0\u5f71\u54cd\u6162\u6027\u810a\u9ad3\u635f\u4f24\u540e\u79fb\u690d\u533a\u57df\u7279\u5f02\u6027\u4eba\u7c7b\u810a\u9ad3\u795e\u7ecf\u7956\u7ec6\u80de\uff08sNPC\uff09\u7684\u5206\u5316<\/td>\n<td>hiPSC-\u810a\u9ad3NPC<\/td>\n<td>\u5927\u9f20\uff0cT8\/9 \u4e2d\u5ea6\u632b\u4f24<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">8\u5468\/\u5e74<\/span><\/span><\/td>\n<td>3 \u4e2a\u72ec\u7acb\u90e8\u4f4d\uff1a\u5599\u90e8\u3001\u5c3e\u90e8\u548c\u75c5\u53d8\u90e8\u4f4d<\/td>\n<td>\u5c3e\u795e\u7ecf\u7535\u523a\u6fc0\u7622\u75d5\u6d88\u878d\u672f<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">16wpt<\/span><\/span><\/td>\n<td>BBB\u3001<br \/>\n\u51af\u5f17\u96f7\u6d4b\u8bd5<\/td>\n<td>\u8054\u5408\u6cbb\u7597\u4fc3\u8fdb\u4e86NPC\u7684\u5206\u5316\u548c\u6574\u5408\u3001\u9ad3\u9798\u518d\u751f\u3001\u589e\u52a0\u4e86\u8840\u6e05\u7d20\u80fd\u795e\u7ecf\u5143\u7684\u8868\u8fbe\u3002<\/td>\n<\/tr>\n<tr>\n<td>Shibata\u7b49\u4eba\uff0c2023<sup>65<\/sup><\/td>\n<td>\u5eb7\u590d\u8bad\u7ec3\u589e\u5f3a\u4eba\u7c7biPSC\u884d\u751f\u795e\u7ecf\u5e72\u7ec6\u80de\/\u7956\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684\u7597\u6548<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">hiPSC-NSPC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c0f\u9f20\uff0cT10\u632b\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">7\u5468<\/span><\/span><\/td>\n<td>\u53d7\u4f24\u9707\u4e2d\u5934\u4fa7\u548c\u5c3e\u4fa7\u5404 2 \u4e2a\u70b9<\/td>\n<td>\u8dd1\u6b65\u673a\u8bad\u7ec3<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">8wpt<\/span><\/span><\/td>\n<td>BMS\u3001\u4f53\u91cd\u8f6c\u68d2\u6d4b\u8bd5\u3001\u56db\u8db3\u6b65\u6001\u5206\u6790\u3001<br \/>\n\u8fd0\u52a8\u5b66\u5206\u6790<\/td>\n<td>\u8054\u5408\u6cbb\u7597\u663e\u8457\u6539\u5584\u4e86\u8fd0\u52a8\u529f\u80fd\u3002<\/td>\n<\/tr>\n<tr>\n<td>Yoshida T\u7b49\u4eba\uff0c2024<sup>66<\/sup><\/td>\n<td>\u6162\u6027\u810a\u9ad3\u635f\u4f24\u518d\u751f\u53ca\u795e\u7ecf\u5e72\u7ec6\u80de\/\u7956\u7ec6\u80de\u79fb\u690d\u3001\u5eb7\u590d\u6cbb\u7597\u548c\u4fe1\u53f7\u86cb\u767d3A\u6291\u5236\u5242\u8054\u5408\u6cbb\u7597<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">hiPSC-NSPC<\/span><\/span><\/td>\n<td>\u88f8\u9f20\uff0cT10\u632b\u4f24<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">7\u5468<\/span><\/span><\/td>\n<td>\u8ddd\u75c5\u53d8\u4e2d\u5fc3\u524d\u7aef\u548c\u5c3e\u7aef1\u6beb\u7c73<\/td>\n<td>\u4fe1\u53f7\u86cb\u767d3A\u6291\u5236\u5242\uff0c\u8dd1\u6b65\u673a\u8bad\u7ec3<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">8wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">BBB <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">MEP<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u91cd\u91cf<\/span><\/span><\/td>\n<td>\u7531\u4e8e\u6539\u5584\u5bbf\u4e3b\u6765\u6e90\u7684\u795e\u7ecf\u5143\u548c\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u5206\u5316\u5e76\u4fc3\u8fdb\u8f74\u7a81\u518d\u751f\uff0cBBB \u8bc4\u5206\u663e\u8457\u63d0\u9ad8<\/td>\n<\/tr>\n<tr>\n<td>Kim JW\u7b49\u4eba\uff0c2024<sup>67<\/sup><\/td>\n<td>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u548c\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\u884d\u751f\u7684\u8fd0\u52a8\u795e\u7ecf\u5143\u7956\u7ec6\u80de\u5728\u810a\u9ad3\u635f\u4f24\u4e2d\u7684\u5206\u6b65\u8054\u5408\u7ec6\u80de\u79fb\u690d<\/td>\n<td>iMNP\u548chMSC<\/td>\n<td>\u5927\u9f20\uff0cT9\u4e2d\u5ea6\u632b\u4f24<\/td>\n<td>hMSCs\uff0824\u5c0f\u65f6\u548c1\u5468\u690d\u5165\u540e\uff09\uff1biMNP\uff086 \u5468\u690d\u5165\u540e\uff09<\/td>\n<td>\u75c5\u53d8\u90e8\u4f4d<\/td>\n<td>\u5206\u6b65\u8054\u5408\u7ec6\u80de\u79fb\u690d<\/td>\n<td>6\u74e6<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8840\u8111\u5c4f\u969c<\/span><\/span><\/td>\n<td>\u9010\u6b65\u7ec6\u80de\u7597\u6cd5\u589e\u5f3a\u4e86 MN \u5206\u5316\u548c\u8f74\u7a81\u518d\u751f\uff0c\u5e76\u6539\u5584\u4e86\u884c\u4e3a\u6062\u590d<\/td>\n<\/tr>\n<tr>\n<td>Kim JW\u7b49\u4eba\uff0c<br \/>\n2024<sup>68<\/sup><\/td>\n<td>\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\u884d\u751f\u7684\u8fd0\u52a8\u795e\u7ecf\u5143\u7956\u7ec6\u80de\u4e0e\u8f90\u7167\u8111\u6e90\u6027\u795e\u7ecf\u8425\u517b\u56e0\u5b50\u8fc7\u8868\u8fbe\u5de5\u7a0b\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7684\u7ec4\u5408\u589e\u5f3a\u4e86\u6162\u6027\u810a\u9ad3\u635f\u4f24\u5927\u9f20\u6a21\u578b\u4e2d\u8f74\u7a81\u518d\u751f\u7684\u6062\u590d<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">hiPSC-NPC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5927\u9f20\uff0cT9\u4e2d\u5ea6\u632b\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6\u5468PI<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u75c5\u53d8\u90e8\u4f4d<\/span><\/span><\/td>\n<td>BDNF-eMSC\u4e0eiMNP\u8054\u5408\u79fb\u690d<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8840\u8111\u5c4f\u969c<\/span><\/span><\/td>\n<td>\u8054\u5408\u7ec6\u80de\u79fb\u690d\u6539\u5584\u4e86\u884c\u4e3a\u6062\u590d\uff0c\u589e\u5f3a\u4e86\u6210\u719f\u8fd0\u52a8\u795e\u7ecf\u5143\u7684\u5206\u5316\u548c\u8f74\u7a81\u518d\u751f\u3002BDNF-eMSC\u901a\u8fc7BDNF\u8868\u8fbe\u4fc3\u8fdb\u795e\u7ecf\u5143\u518d\u751f\u3002<\/td>\n<\/tr>\n<tr>\n<td>Xu\u7b49\u4eba\uff0c2021<sup>69<\/sup><\/td>\n<td>\u4eba\u7c7b\u795e\u7ecf\u524d\u4f53\u7ec6\u80de\u79fb\u690d\u53ef\u9006\u8f6c\u521b\u4f24\u540e\u810a\u9ad3\u7a7a\u6d1e\u75c7\u5927\u9f20\u6a21\u578b\u4e2d\u7684\u7a7a\u6d1e\u751f\u957f<\/td>\n<td>hiPSC-NESC \u548c\u4eba\u80ce\u513f\u810a\u9ad3\u6765\u6e90\u7684 NPC<\/td>\n<td>\u5927\u9f20\uff0cT10\/11\u8f7b\u5ea6\u632b\u4f24\u540e\u810a\u9ad3\u7a7a\u6d1e\u75c7<\/td>\n<td>10\u5468\/\u5e74<\/td>\n<td>\u56ca\u80bf<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">10wpt<\/span><\/span><\/td>\n<td>BBB<br \/>\n\u5361\u7f57\u7433\u65af\u5361\u533b\u5b66\u9662\u6e38\u6cf3\u8bc4\u4f30\u5de5\u5177 \u5e73\u8861\u6728\u6b65\u884c\u6d4b\u8bd5<br \/>\n\u7f51\u683c\u6b65\u884c\u6d4b\u8bd5<\/td>\n<td>\u810a\u9ad3\u9e23\u7ba1\u9006\u5411\u751f\u957f<\/td>\n<\/tr>\n<tr>\n<td>Xu\u7b49\u4eba\uff0c2022<sup>70<\/sup><\/td>\n<td>\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\u6765\u6e90\u7684\u4eba\u7c7b\u795e\u7ecf\u5e72\u7ec6\u80de\u5bf9\u521b\u4f24\u540e\u810a\u9ad3\u7a7a\u6d1e\u75c7\u5927\u9f20\u6a21\u578b\u7684\u591a\u79cd\u6cbb\u7597\u4f5c\u7528<\/td>\n<td>\u7b26\u5408\u4eba\u7c7b GMP\u6807\u51c6\u7684iPSC \u884d\u751f NESC<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5927\u9f20\uff0cT10\/11\u8f7b\u5ea6\u632b\u4f24\u540e\u810a\u9ad3\u7a7a\u6d1e\u75c7<\/span><\/span><\/td>\n<td>\u611f\u67d3\u540e 10 \u5468\uff08\u6162\u6027\u671f\uff09<br \/>\n\u611f\u67d3\u540e 1 \u5468\uff08\u4e9a\u6025\u6027\u671f\uff09<\/td>\n<td>\u75c5\u53d8\u90e8\u4f4d\u7684\u5b9e\u8d28\uff081\u5468\uff09\u6216\u56ca\u80bf\u5185\uff0810\u5468\uff09<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">10wpt<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td>\u79fb\u690d\u7684 NESC \u53ef\u6291\u5236\u56ca\u80bf\u5f62\u6210\u548c\u6269\u5f20\uff0c<br \/>\n\u8c03\u8282\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\u548c\u6d3b\u6027\u5c0f\u80f6\u8d28\u7ec6\u80de\/\u5de8\u566c\u7ec6\u80de\uff0c\u4fc3\u8fdb\u8f74\u7a81\u518d\u751f<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<h2 id=\"sectitle0070\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E6%85%A2%E6%80%A7%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\"><\/span><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5c3d\u7ba1\u4ecd\u6709\u8bb8\u591a\u5173<a href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/19199.html\/\" target=\"_blank\" rel=\"noopener\">\u4e8e\u7ec6\u80de\u6cbb\u7597<\/a>\u7684\u5b9e\u9645\u95ee\u9898\u548c\u751f\u7269\u5b66\u95ee\u9898\u6709\u5f85\u4e25\u683c\u89e3\u51b3\uff0c\u4f46\u8fd1\u51e0\u5341\u5e74\u6765\uff0c\u57fa\u4e8e\u5148\u524d\u52a8\u7269\u5b9e\u9a8c\u7684\u7ec6\u80de\u7597\u6cd5\u5df2\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u9010\u6e10\u53d1\u5c55\u8d77\u6765\u3002\u96ea\u65fa\u7ec6\u80de\u3001\u5de8\u566c\u7ec6\u80de\u3001\u55c5\u9798\u7ec6\u80de\u548c\u5404\u79cd\u7c7b\u578b\u7684\u5e72\u7ec6\u80de\uff0c\u5305\u62ecNSC\u548c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff0c\u90fd\u5df2\u88ab\u7814\u7a76\u3002\u7136\u800c\uff0c\u5c1a\u672a\u4ece\u8fd9\u4e9b\u7597\u6cd5\u5728\u60a3\u8005\u8eab\u4e0a\u8fdb\u884c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u83b7\u5f97\u53ef\u91cd\u590d\u7684\u4e34\u5e8a\u7597\u6548\u8bc1\u636e\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c<\/p>\n<p>\u57fa\u4e8eNSPC\u7684\u7597\u6cd5\u88ab\u89c6\u4e3a\u4e00\u4e2a\u65b0\u7684\u673a\u4f1a\u4e4b\u7a97\uff0c\u76f8\u5173\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u8bc1\u660e\u5c06\u7ec6\u80de\u79fb\u690d\u5230\u53d7\u635f\u810a\u9ad3\u7684\u53ef\u884c\u6027\u548c\u957f\u671f\u5b89\u5168\u6027\u3002<strong>\u6211\u4eec\u7684\u641c\u7d22\u7b56\u7565\u786e\u5b9a\u4e86\u516d\u9879\u5173\u4e8eNSPC\u9ad3\u5185\u79fb\u690d\u7684\u5df2\u53d1\u8868\u7814\u7a76\u4ee5\u53ca\u4e09\u9879\u5728clinicaltrials.gov\u4e0a\u6ce8\u518c\u7684\u6b63\u5728\u8fdb\u884c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/strong><\/p>\n<h3 id=\"sectitle0075\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%BA%BA%E7%B1%BB%E8%83%8E%E5%84%BF%E8%84%91%E6%88%96%E8%84%8A%E9%AB%93%E6%9D%A5%E6%BA%90%E7%9A%84NSPC\"><\/span><strong>\u4eba\u7c7b\u80ce\u513f\u8111\u6216\u810a\u9ad3\u6765\u6e90\u7684NSPC<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u79fb\u690d\u7684NSC\u4e3b\u8981\u4e3a\u4eba\u80ce\u8111\u6765\u6e90\u7684NSC\uff08HuCNS-SC\u00ae\uff0cStemcells, Inc.\uff0c\u7f8e\u56fd\u52a0\u5229\u798f\u5c3c\u4e9a\u5dde\u7ebd\u74e6\u514b\uff09\u548c\u4eba\u80ce\u810a\u9ad3\u6765\u6e90\u7684NSC\uff08NSI-566\u7ec6\u80de\uff0cNeuralstem Inc.\uff0c\u7f8e\u56fd\u9a6c\u91cc\u5170\u5dde\uff09\u3002<\/p>\n<p>2015\u5e74\u62a5\u9053\u7684\u97e9\u56fd\u4e00\u9879\u4eba\u80ce\u8111\u6765\u6e90\u7684NSPC\u79fb\u690d\u6cbb\u7597\u6162\u6027SCI\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5165\u7ec4\u4e8619\u4f8b\u521b\u4f24\u6027\u9888\u690eSCI\u60a3\u8005\u4f5c\u4e3a\u5b9e\u9a8c\u7ec4\uff0c\u5176\u4e2d\u611f\u89c9\u8fd0\u52a8\u5b8c\u5168\u7f3a\u967717\u4f8b\uff0c\u8fd0\u52a8\u5b8c\u5168\u4f46\u4e0d\u5b8c\u5168\u611f\u89c9\u7f3a\u96772\u4f8b\uff0c\u5bf9\u7167\u7ec415\u4f8b\u672a\u63a5\u53d7\u7ec6\u80de\u79fb\u690d\u3002<strong>\u968f\u8bbf1\u5e74\u53d1\u73b0\uff0c19\u4f8b\u79fb\u690d\u60a3\u8005\u4e2d5\u4f8b\u7f8e\u56fd\u810a\u9ad3\u635f\u4f24\u534f\u4f1a\u635f\u4f24\u91cf\u8868\uff08AIS\uff09\u5206\u7ea7\u6539\u5584\uff0c\u5176\u4e2d2\u4f8b\uff08A\u2192C\uff09\uff0c1\u4f8b\uff08A\u2192B\uff09\uff0c2\u4f8b\uff08B\u2192D\uff09\uff0c\u540c\u65f6\u8fd0\u52a8\u8bc4\u5206\u548c\u7535\u751f\u7406\u68c0\u67e5\u53cd\u5e94\u6539\u5584\u7b49\u5176\u4ed6\u83b7\u76ca\uff0c\u8bc1\u660e\u4e86NSPC\u79fb\u690d\u6cbb\u7597\u6162\u6027SCI\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027<\/strong>\u3002\u8be5\u7814\u7a76\u53d7\u5230\u60a3\u8005\u6570\u91cf\u5c11\u548c\u968f\u8bbf\u671f\u77ed\u7684\u5c40\u9650\u6027\u3002<\/p>\n<p>\u968f\u7740\u5e72\u7ec6\u80de\u57f9\u517b\u6280\u672f\u7684\u4e0d\u65ad\u53d1\u5c55\uff0c\u51fa\u73b0\u4e86\u51e0\u79cd\u7528\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u7684NSC\u4ea7\u54c1\u3002HuCNS-SC\u00ae\u7684\u5b89\u5168\u6027\u5df2\u5728\u9488\u5bf9\u5176\u4ed6\u75be\u75c5\u7684\u51e0\u9879\u5df2\u5b8c\u6210\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5f97\u5230\u8bc1\u5b9e\uff0c\u5305\u62ec\u795e\u7ecf\u5143\u8721\u6837\u8102\u8910\u8d28\u6c89\u79ef\u75c7\u3001\u4f69\u5229\u624e\u4f0a\u65af-\u6885\u8328\u5df4\u8d6b\u75c5\u548c\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\u3002\u7528\u4e8e\u7ec6\u80de\u79fb\u690d\u7684\u624b\u52a8\u9ad3\u5185\u6ce8\u5c04\u6280\u672f\u5df2\u5728\u60a3\u8005\u8eab\u4e0a\u8fdb\u884c\u4e86\u6d4b\u8bd5\uff0c\u4ee5\u8fdb\u4e00\u6b65\u9610\u660e\u4eba\u4f53\u5bf9\u7ec6\u80de\u5242\u91cf\u548c\u4f53\u79ef\u7684\u6269\u5927\u3002<\/p>\n<p>\u6709\u53f2\u4ee5\u6765\u7b2c\u4e00\u6b21\u591a\u4e2d\u5fc3I\/IIa\u671f\u8bd5\u9a8c\u901a\u8fc7\u624b\u672f\u5c06HuCNS-SC\u00ae\u79fb\u690d\u523012\u540dAISA\u7ea7\u6216B\u7ea7\u53d7\u8bd5\u8005\u7684\u80f8\u6bb5\u810a\u9ad3\u4e2d\uff0c\u5e76\u6536\u96c6\u4e866\u5e74\u7684\u968f\u8bbf\u6570\u636e\uff0c\u5305\u62ec\u5b89\u5168\u6027\u8bc4\u4f30\u3001\u611f\u89c9\u9608\u503c\u6d4b\u91cf\u548c\u795e\u7ecf\u5f71\u50cf\u5b66\u6570\u636e\u3002<strong>\u8be5\u7814\u7a76\u63ed\u793a\u4e86\u77ed\u671f\u548c\u957f\u671f\u624b\u672f\u7684\u5b89\u5168\u6027\u548c\u53ef\u884c\u6027\uff0c\u521d\u6b65\u7597\u6548\u6d4b\u91cf\u786e\u5b9a\u4e86\u90e8\u5206\u8282\u6bb5\u611f\u89c9\u6539\u5584\uff0c\u4f46\u6ca1\u6709\u8fd0\u52a8\u529f\u80fd\u76f8\u5173\u8bc4\u5206<\/strong>\u3002<\/p>\n<p>\u6839\u636e\u672c\u7814\u7a76\u4e2d\u786e\u5b9a\u7684\u80f8\u690e\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u7684\u5b89\u5168\u6027\u6982\u51b5\uff0c\u4e00\u9879II\u671f\u589e\u91cf\u5242\u91cf\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7814\u7a76\u7684<strong>\u81f3\u5c119\u4e2a\u6708\u968f\u8bbf\u6570\u636e\u8bc1\u660e\u4e86HuCNS-SC\u00ae\u79fb\u690d\u6cbb\u7597\u6162\u6027\u9888\u690e\u810a\u9ad3\u635f\u4f24\u7684\u5b89\u5168\u6027\u548c\u53ef\u884c\u6027\uff0c\u5e76\u4e14\u603b\u4f53\u5e73\u5747\u529f\u80fd\u7ed3\u679c\u6307\u6807\u5448\u6539\u5584\u8d8b\u52bf<\/strong>\u3002<\/p>\n<p>\u7136\u800c\uff0c\u7531\u4e8e\u7533\u529e\u65b9\u63d0\u524d\u7ec8\u6b62\u7814\u7a76\uff0c\u968f\u8bbf\u6570\u636e\u6709\u9650\u3002\u7531\u4e8e\u968f\u8bbf12\u4e2a\u6708\u7684\u53d7\u8bd5\u8005\u6570\u91cf\u592a\u5c11\uff0c\u65e0\u6cd5\u5f97\u51fa\u5173\u4e8e\u4e34\u5e8a\u7597\u6548\u7684\u8fdb\u4e00\u6b65\u7ed3\u8bba\u3002<\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5728\u4e00\u9879\u9996\u6279\u4f7f\u7528\u4eba\u810a\u9ad3\u6e90\u6027\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSPC\uff09\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u56db\u540dT2-T12\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u63a5\u53d7\u4e86\u516d\u6b21\u53cc\u4fa7\u4e2d\u7ebf\u7acb\u4f53\u5b9a\u5411\u6ce8\u5c04NSI-566\u7ec6\u80de\u3002\u79fb\u690d\u540e18-27\u4e2a\u6708\u7684\u968f\u8bbf\u6570\u636e\u663e\u793a\uff0c<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6240\u6709\u53d7\u8bd5\u8005\u5747\u672a\u51fa\u73b0\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff0c\u4ec5\u6709\u4e24\u540d\u53d7\u8bd5\u8005\u51fa\u73b0\u90e8\u5206\u795e\u7ecf\u529f\u80fd\u6539\u5584<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u3002\u7136\u800c\uff0c\u672c\u7814\u7a76\u7eb3\u5165\u7684\u60a3\u8005\u6570\u91cf\u8f83\u5c11\uff0c\u6700\u5927\u7684\u5c40\u9650\u6027\u5728\u4e8e\u7f3a\u4e4f\u5bf9\u7167\u7ec4\u3002<\/span><\/span><\/p>\n<h3 id=\"sectitle0080\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%AD%A3%E5%9C%A8%E8%BF%9B%E8%A1%8C%E7%9A%84hNSPC%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E6%85%A2%E6%80%A7SCI%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6b63\u5728\u8fdb\u884c\u7684hNSPC\u79fb\u690d\u6cbb\u7597\u6162\u6027SCI\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u76ee\u524d\uff0c\u6709\u4e09\u9879\u5173\u4e8e\u6162\u6027SCI\u60a3\u8005hNSPC\u79fb\u690d\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5728\u8fdb\u884c\u4e2d\uff0c\u8fd9\u4e9b\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u5728ClinicalTrials.gov\u4e0a\u6ce8\u518c\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">I\u671f\u4e34\u5e8a\u8bd5\u9a8cNCT01772810\u4e8e2014\u5e748\u6708\u542f\u52a8\uff0c\u5176\u4e2d\u79fb\u690d\u4eba\u810a\u9ad3\u6765\u6e90\u7684NSC\u6cbb\u7597\u6162\u6027AIS A\u7ea7SCI\u3002 I\u671f\u4e34\u5e8a\u8bd5\u9a8cNCT04205019\u4e8e2020\u5e7411\u670814\u65e5\u5f00\u59cb\uff0c\u65e8\u5728\u8bc4\u4f30\u9798\u5185\u5e94\u7528\u795e\u7ecf\u7ec6\u80de\u6cbb\u7597\u6162\u6027\u521b\u4f24\u6027\u5b8c\u5168\u6027\uff08AISA\u7ea7\uff09\u6216\u4e0d\u5b8c\u5168\u6027\uff08AIS B\/C \u7ea7\uff09SCI\u7684\u5b89\u5168\u6027\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">II\u671f\u4e34\u5e8a\u8bd5\u9a8cNCT02688049\u4e8e2016\u5e741\u6708\u5f00\u59cb\uff0c\u5728\u5c40\u90e8\u75a4\u75d5\u53bb\u9664\u548c\u5168\u9762\u7684\u672f\u540e\u5eb7\u590d\u3001\u5fc3\u7406\u548c\u8425\u517b\u63aa\u65bd\u540e\uff0c\u79fb\u690d\u5e26\u6709NeuroRegen\u652f\u67b6\u7684NSC\u3002\u7eb3\u5165\u7684\u6162\u6027SCI NSPC\u79fb\u690d\u4e34\u5e8a\u8bd5\u9a8c\u7684\u7279\u5f81\u5982\u88683\u6240\u793a\u3002<\/span><\/span><\/p>\n<p id=\"tspara0030\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u88683\uff1a\u4eba\u7c7bNSPC\u79fb\u690d\u6cbb\u7597\u6162\u6027SCI\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/span><\/span><\/p>\n<figure class=\"wp-block-table is-style-stripes\" style=\"font-size: 13px;\">\n<table class=\"has-fixed-layout\">\n<thead>\n<tr>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f5c\u8005\u3001\u5e74\u4efd\u3001\u56fd\u5bb6<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6807\u9898PMID <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">NCT<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53c2\u4e0e\u8005<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7ec6\u80de\u6765\u6e90<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53d7\u4f24\u90e8\u4f4d<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7814\u7a76\u8bbe\u8ba1\u9636\u6bb5<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u79fb\u690d\u90e8\u4f4d<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8054\u5408\u6cbb\u7597<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u968f\u8bbf\u65f6\u957f<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e3b\u8981\u7ed3\u679c\u6307\u6807<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th colspan=\"10\"><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u80ce\u8111\u6765\u6e90\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/span><\/span><\/strong><\/th>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Shin, J. \u7b49\u4eba\uff0c<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2015\uff0c\u97e9\u56fd<\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">73<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">PMID 26568892 , KCT0000879<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u521b\u4f24\u6027\u9888\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u4eba\u80ce\u513f\u8111\u6e90\u6027\u795e\u7ecf\u5e72\/\u7956\u7ec6\u80de\u79fb\u690d\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ep = 34 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">tp = 34 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">cp = 15 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ip = 19<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u80ce\u8111\u6765\u6e90\u7684NSPC<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">C3\u2013C8<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5355\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7e\u3001\u975e\u968f\u673a\u5bf9\u7167<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">I\/IIa \u671f<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8ddd\u75c5\u7076\u4e2d\u5fc3\u524d\u7aef\u548c\u5c3e\u7aef5 \u6beb\u7c73<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">1\u5e74<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b89\u5168\u6027\uff1a\u65e0\u810a\u9ad3\u635f\u4f24\u3001\u7a7a\u6d1e\u6216\u80bf\u7624\u5f62\u6210\u3001\u795e\u7ecf\u529f\u80fd\u6076\u5316\u4ee5\u53ca\u795e\u7ecf\u6027\u75bc\u75db\u6216\u75c9\u631b\u52a0\u5267\u7684\u8bc1\u636e\u3002<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7597\u6548\uff1a19\u4f8b\u79fb\u690d\u60a3\u8005\u4e2d\uff0c5\u4f8bAIS\u5206\u7ea7\u6539\u5584\uff1a2\u4f8b\uff08A\u2192C\uff09\uff0c1\u4f8b\uff08A\u2192B\uff09\uff0c2\u4f8b\uff08B\u2192D\uff09\uff0c\u5bf9\u7167\u7ec41\u4f8bAIS\u5206\u7ea7\u6539\u5584\uff08A\u2192B\uff09\u3002<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Levi, A.\u7b49\u4eba\uff0c<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2018\uff0c\u7f8e\u56fd<\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">77<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">PMID 28541431\uff1bNCT01321333\uff1bNCT 02163876<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6162\u6027\u9888\u80f8\u810a\u9ad3\u635f\u4f24\u4e2d\u4eba\u7c7b\u795e\u7ecf\u5e72\u7ec6\u80de\u9ad3\u5185\u79fb\u690d\u7684\u5b89\u5168\u6027<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ep = 43 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">tp = 41 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">cp = 12 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ip = 29<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7b\u80ce\u513f\u8111\u6e90\u6027\u795e\u7ecf\u5e72\u7ec6\u80de(HuCNS-SC\u00ae)<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">C5\u2013C7 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">T2\u2013T12<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u591a\u4e2d\u5fc3\u3001\u5355\u76f2\u3001\u5bf9\u7167I\/II \u671f\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u810a\u9ad3\u635f\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">1\u5e74<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b89\u5168\u6027\uff1a\u4e0d\u5b58\u5728\u4e0e\u7ec6\u80de\u6216\u624b\u52a8\u9ad3\u5185\u6ce8\u5c04\u76f8\u5173\u7684\u5b89\u5168\u95ee\u9898\u3002<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Curt\uff0cA.\u7b49\u4eba\uff0c2020\u5e74\uff0c\u745e\u58eb\u548c\u52a0\u62ff\u5927<\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">78<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">PMID 32698674\uff1bNCT 01217008<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53d7\u635f\u810a\u9ad3\u662f\u5e72\u7ec6\u80de\u79fb\u690d\u7684\u5408\u9002\u76ee\u6807<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ep = 12 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">tp = 12 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">cp = 0 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ip = 12<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7b\u80ce\u513f\u8111\u6e90\u6027\u795e\u7ecf\u5e72\u7ec6\u80de(HuCNS-SC\u00ae)<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">T2\u2013T11<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7e\u3001\u53d7\u63a7II \u671f<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53d7\u4f24\u90e8\u4f4d\u7684\u4e0a\u65b9\u548c\u4e0b\u65b9<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6\u5e74<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b89\u5168\u6027\uff1a\u624b\u672f\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\uff1a\u8111\u810a\u6db2\u6f0f\u3001\u5047\u6027\u8111\u819c\u81a8\u51fa\u7b49\u3002\u65e0\u4e34\u5e8a\u529f\u80fd\u635f\u5bb3\uff0c\u672a\u53d1\u73b0\u80bf\u7624\u3002<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7597\u6548\uff1a12\u4f8b\u60a3\u8005\u4e2d5\u4f8b\u83b7\u5f97\u8282\u6bb5\u6027\u611f\u89c9\u6539\u5584\u3002<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Levi, A.\u7b49\u4eba\uff0c<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2019 \u5e74\uff0c\u7f8e\u56fd<\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">79<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">PMID 30180779\uff1bNCT 02163876<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6162\u6027\u9888\u810a\u9ad3\u635f\u4f24\u4eba\u7c7b\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u591a\u4e2d\u5fc3\u7814\u7a76\u7684\u4e34\u5e8a\u7ed3\u679c<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ep = 31 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">tp = 16 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">cp = 4 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ip = 12<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7b\u80ce\u513f\u8111\u6e90\u6027\u795e\u7ecf\u5e72\u7ec6\u80de(HuCNS-SC\u00ae)<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">C5\u2013C7<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u591a\u4e2d\u5fc3\u3001\u5355\u76f2\u3001\u5bf9\u7167II \u671f<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u75c5\u53d8\u4e2d\u5fc3\u7684\u524d\u7aef\u548c\u5c3e\u7aef<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">1\u5e74<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b89\u5168\u6027\uff1aMRI \u68c0\u67e5\u672a\u53d1\u73b0\u989d\u5916\u810a\u9ad3\u635f\u4f24\u3001\u65b0\u53d1\u75c5\u7076\u6216\u7a7a\u6d1e\u5f62\u6210\u7684\u8bc1\u636e\uff0c\u79fb\u690d\u7ec4\u5728\u514d\u75ab\u6291\u5236\u671f\u95f4\u4ec5\u53d1\u751f\u4e00\u4f8b\u611f\u67d3\u76f8\u5173\u7684\u624b\u672f\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6(SAE)\u3002<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7597\u6548\uff1a\u6574\u4f53UEMS \u548cGRASSP \u5f3a\u5ea6\u6307\u6807\u5747\u6709\u6240\u6539\u5584\u3002<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Ghobrial \u7b49\u4eba\uff0c2017 \u5e74\uff0c\u7f8e\u56fd\u548c\u52a0\u62ff\u5927<\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">80<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">PMID 28899046\uff1bNCT 02163876<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7b\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u9888\u810a\u9ad3\u635f\u4f24\uff1aII \u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d12 \u4e2a\u6708\u7684\u529f\u80fd\u7ed3\u679c<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ep = 17 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">tp = 5 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">cp = 1 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ip = 4<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7b\u80ce\u513f\u8111\u6e90\u6027\u795e\u7ecf\u5e72\u7ec6\u80de(HuCNS-SC\u00ae)<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">C5\u2013C7<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u591a\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7e\u3001\u53d7\u63a7II \u671f<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u635f\u4f24\u4e2d\u5fc3\u7684\u524d\u7aef\u548c\u5c3e\u90e8<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">1\u5e74<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b89\u5168\u6027\uff1a\u810a\u9ad3\u6ce8\u5c04\u672a\u53d1\u73b0\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7597\u6548\uff1a\u5bf9\u7167\u7ec4\u548c\u6cbb\u7597\u7ec4\u7684ISNCSCI\u548cGRASSP\u6539\u5584\u7a0b\u5ea6\u76f8\u5f53\u3002<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<th colspan=\"10\"><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7b\u80ce\u513f\u810a\u9ad3\u6765\u6e90\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/span><\/span><\/strong><\/th>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Curtis, E. \u7b49\u4eba\uff0c<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2018\uff0c\u7f8e\u56fd<\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">81<\/span><\/span><\/sup><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">PMID 29859175\uff1bNCT 01772810<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684\u9996\u6b21\u4eba\u4f53I\u671f\u7814\u7a76<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ep = 4 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">tp = 4 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">cp = 0 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ip = 4<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7b\u80ce\u513f\u810a\u9ad3\u6765\u6e90\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSI-566\uff09<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">T2\u2013T12<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5355\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7e\u3001\u975e\u5bf9\u7167I \u671f<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8ddd\u635f\u4f24\u90e8\u4f4d\u5269\u4f59\u7ec4\u7ec7\u8fb9\u7f18\u5916\u4fa71 \u6beb\u7c73<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">18\u201327\u4e2a\u6708<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b89\u5168\u6027\uff1a\u65e0\u624b\u672f\u76f8\u5173\u5e76\u53d1\u75c7\uff0c\u65e0\u81ea\u53d1\u6027\u6216\u8bf1\u53d1\u6027\u75bc\u75db\uff0cMRI \u65e0\u5b89\u5168\u95ee\u9898\u3002<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7597\u6548\uff1a\u4f7f\u7528ISNCSCI \u8fd0\u52a8\u548c\u611f\u89c9\u8bc4\u5206\u57282\/4 \u60a3\u8005\u4e2d\u68c0\u6d4b\u5230\u4e00\u5230\u4e24\u4e2a\u6c34\u5e73\u7684\u795e\u7ecf\u7cfb\u7edf\u6539\u5584\u3002<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<th colspan=\"10\"><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5728clinicaltrials.gov<\/span><\/span><\/strong><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e0a\u6ce8\u518c\u7684\u6b63\u5728\u8fdb\u884c\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/strong><\/th>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6234\u5efa\u519b\uff0c2016\uff0c\u4e2d\u56fd<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">NCT02688049 NeuroRegen Scaffold\u2122\u8054\u5408\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6216\u795e\u7ecf\u5e72\u7ec6\u80de\u4fee\u590d\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7597\u6548\u548c\u5b89\u5168\u6027<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ep = 30<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">NSCs \u6216\u95f4\u5145\u8d28\u5e72\u7ec6\u80de<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">C5\u2013T12<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5355\u4e2d\u5fc3\u3001\u968f\u673a<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53cc\u76f2<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">I\/II \u671f<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u810a\u9ad3\u635f\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">NeuroRegen\u652f\u67b6<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2\u5e74<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7814\u7a76<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">de Munter JP \u7b49\uff0c2019\uff0c\u897f\u73ed\u7259<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">NCT 04205019<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u810a\u9ad3\u635f\u4f24\u4e2d\u7684\u5b89\u5168\u5e72\u7ec6\u80de<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ep = 10<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u795e\u7ecf\u7ec6\u80de\uff08\u542b\u6709\u81ea\u4f53\u65b0\u9c9c\u5e72\u7ec6\u80de\uff09<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">C5\u2013T12<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5355\u4e2d\u5fc3\u3001\u5f00\u653e\u6807\u7b7eI \u671f<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u810a\u9ad3\u635f\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2\u5e74<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b89\u5168\u6027\u7814\u7a76<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Ciacci, J.\uff0c<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2022\uff0c\u7f8e\u56fd<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">NCT 01772810<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7b\u810a\u9ad3\u6e90\u6027\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684\u5b89\u5168\u6027\u7814\u7a76<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">ep = 8<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u7c7b\u80ce\u513f\u810a\u9ad3\u6765\u6e90\u7684NSC\uff08Neuralstem Inc.\uff09<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">T2\u2013T12 <\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">C5\u2013C7<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5355\u4e2d\u5fc3\u5f00\u653e\u6807\u7b7e\u3001\u975e\u5bf9\u7167I \u671f<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u810a\u9ad3\u635f\u4f24<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6ca1\u6709\u4efb\u4f55<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">5\u5e74<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b89\u5168\u6027\u7814\u7a76<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6b64\u5916\uff0c\u9996\u9879\u9488\u5bf9\u4e9a\u6025\u6027\u5b8c\u5168\u6027\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u7684iPSC\u884d\u751fNSPC\u79fb\u690d<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5df2\u7ecf\u542f\u52a8\u3002\u672a\u6765\u4ecd\u9700\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u7531hiPSCs\u6216hESCs\u884d\u751f\u7684\u4eba\u6e90NSPCs\u5728\u6162\u6027SCI\u60a3\u8005\u4e2d\u7684\u79fb\u690d\u5b89\u5168\u6027\u4e0e\u6709\u6548\u6027\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u603b\u7684\u6765\u8bf4\uff0c\u76ee\u524d\u9488\u5bf9\u6162\u6027SCI\u7684NSPC\u79fb\u690d\u6cbb\u7597\u4e3b\u8981\u4ee5<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b89\u5168\u6027\u4e0e\u53ef\u884c\u6027<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f5c\u4e3a\u4e34\u5e8a\u7ed3\u5c40\u6307\u6807\u3002\u8981\u8fdb\u4e00\u6b65\u5f97\u51fa\u4e34\u5e8a\u7597\u6548\u7ed3\u8bba\uff0c\u8fd8\u9700\u8981\u66f4\u591a\u75c5\u4f8b\u5165\u7ec4\u3001\u66f4\u957f\u968f\u8bbf\u4ee5\u53ca\u5339\u914d\u7684\u5bf9\u7167\u7ec4\u3002\u7136\u800c\uff0c\u5982\u679c\u4e0d\u80fd\u660e\u786e\u8bc1\u660e\u4f9b\u4f53\u7ec6\u80de\u7684\u5b58\u6d3b\uff0c\u4e34\u5e8a\u7597\u6548\u5c31\u7f3a\u4e4f\u5b9e\u8d28\u610f\u4e49\u3002\u4e3a\u4fc3\u8fdb\u79fb\u690dNSPCs\u7684\u5b58\u6d3b\u3001\u5206\u5316\u4e0e\u6574\u5408\uff0c\u63d0\u4f9b\u826f\u597d\u7684\u79fb\u690d\u7269\u73af\u5883\u81f3\u5173\u91cd\u8981\uff0c\u5305\u62ec\u9ad8\u6548\u7684\u514d\u75ab\u6291\u5236\u6216\u964d\u4f4e\u79fb\u690d\u7269\u514d\u75ab\u539f\u6027\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u8fd8\u9700\u8981\u501f\u52a9\u5148\u8fdb\u7684\u5f71\u50cf\u5b66\u6216\u5149\u9057\u4f20\u5b66\u65b9\u6cd5\u6765\u9a8c\u8bc1\u79fb\u690d\u7ec6\u80de\u7684\u529f\u80fd\u6d3b\u6027\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e34\u5e8a\u8f6c\u5316\u7684\u91cd\u70b9\u4e0d\u4ec5\u5728\u4e8e\u6539\u8fdb\u4e34\u5e8a\u524d\u7814\u7a76\u8bbe\u8ba1\uff0c\u66f4\u5728\u4e8e\u540e\u7eed\u4e34\u5e8a\u8bd5\u9a8c\u7684\u5408\u7406\u8bbe\u8ba1\u4e0e\u89c4\u8303\u5b9e\u65bd\u3002\u76ee\u524d\uff0c\u9488\u5bf9SCI\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6307\u5357\u5df2\u88ab\u5236\u5b9a\u3002<\/span><\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E6%80%BB%E7%BB%93%E4%B8%8E%E5%B1%95%E6%9C%9B\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u603b\u7ed3\u4e0e\u5c55\u671b<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%B2%BB%E7%96%97%E6%BD%9C%E5%8A%9B%E4%B8%8E%E6%9C%BA%E5%88%B6%E8%BF%9B%E5%B1%95\"><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6cbb\u7597\u6f5c\u529b\u4e0e\u673a\u5236\u8fdb\u5c55<\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5e72\u7ec6\u80de\u7814\u7a76\u5df2\u88ab\u5217\u4e3a\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u6cbb\u7597\u7684\u5341\u5927\u6838\u5fc3\u65b9\u5411\u4e4b\u4e00\uff0c\u5176\u4e2d\u795e\u7ecf\u5e72\/\u7956\u7ec6\u80de\uff08NSPCs\uff09\u5c55\u73b0\u51fa\u663e\u7740\u7684\u4fee\u590d\u6f5c\u529b\u3002\u5f53\u524dNSPCs\u6765\u6e90\u5e7f\u6cdb\uff0c\u6db5\u76d6\u80da\u80ce\/\u6210\u4f53\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u3001\u80da\u80ce\u5e72\u7ec6\u80de\uff08ESCs\uff09\u3001\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSCs\uff09\u53ca\u76f4\u63a5\u91cd\u7f16\u7a0b\u7684\u975e\u795e\u7ecf\u7ec6\u80de\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5728\u52a8\u7269\u6a21\u578b\u4e2d\uff0c\u79fb\u690dNSPCs\u901a\u8fc7<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u91cd\u5efa\u795e\u7ecf\u4e2d\u7ee7\u901a\u8def\u3001\u8c03\u8282\u5fae\u73af\u5883\uff08\u5982\u51cf\u8f7b\u708e\u75c7\uff09\u3001\u6fc0\u6d3b\u5185\u6e90\u5e72\u7ec6\u80de\u53ca\u4fc3\u8fdb\u8f74\u7a81\u518d\u751f\u4e0e\u9ad3\u9798\u5f62\u6210<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53d1\u6325\u529f\u80fd\u4fee\u590d\u4f5c\u7528\u3002\u4eba\u6e90NSPCs\uff08hNSPCs\uff09\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u5176\u5b89\u5168\u6027\u4e0e\u521d\u6b65\u7597\u6548\uff0c\u4f8b\u5982\u5168\u7403\u9996\u4f8biPSC\u884d\u751f\u810a\u9ad3\u7279\u5316\u795e\u7ecf\u524d\u4f53\u7ec6\u80de\uff08\u5982XS228\u7ec6\u80de\u6ce8\u5c04\u6db2\uff09\u7684\u79fb\u690d\u5df2\u5728\u4e2d\u56fd\u5b8c\u6210\u9996\u4f8b\u7ed9\u836f\uff0c\u60a3\u8005\u8fd0\u52a8\u529f\u80fd\u83b7\u5f97\u6539\u5584\u3002<\/span><\/span><\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%B4%E5%BA%8A%E8%BD%AC%E5%8C%96%E6%8C%91%E6%88%98%E4%B8%8E%E6%A0%87%E5%87%86%E5%8C%96%E9%9C%80%E6%B1%82\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e34\u5e8a\u8f6c\u5316\u6311\u6218\u4e0e\u6807\u51c6\u5316\u9700\u6c42<\/span><\/span><\/strong><span 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inherit;\">\u53c2\u8003\u8d44\u6599\uff1a[1]:https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2324242625000452<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: 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