{"id":19245,"date":"2025-09-25T04:17:39","date_gmt":"2025-09-24T12:17:39","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/stem-cells\/nsc\/19245.html"},"modified":"2025-10-10T15:34:14","modified_gmt":"2025-10-10T07:34:14","slug":"https-www-hjtdsm-cn-stem-cells-nsc-19245-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html","title":{"rendered":"\u0632\u0631\u0627\u0639\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629 \u0644\u0625\u0635\u0627\u0628\u0627\u062a \u0627\u0644\u062d\u0628\u0644 \u0627\u0644\u0634\u0648\u0643\u064a: \u062a\u062d\u0644\u064a\u0644 \u0622\u0644\u064a\u0627\u062a \u0627\u0644\u0625\u0635\u0644\u0627\u062d\u060c \u0648\u0627\u062e\u062a\u0631\u0627\u0642\u0627\u062a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0627\u0644\u0622\u0641\u0627\u0642 \u0627\u0644\u0627\u0646\u062a\u0642\u0627\u0644\u064a\u0629 \u0641\u064a \u0639\u0627\u0645 2025"},"content":{"rendered":"<p>\u810a\u9ad3\u635f\u4f24 (SCI) \u4f1a\u5bfc\u81f4\u5c40\u90e8\u795e\u7ecf\u5143\u6b7b\u4ea1\uff0c\u4ee5\u53ca\u8fde\u63a5\u5927\u8111\u548c\u810a\u9ad3\u7684\u4e0a\u884c\u548c\u4e0b\u884c\u8f74\u7a81\u7684\u65ad\u88c2\u3002\u81ea\u4e00\u4e2a\u591a\u4e16\u7eaa\u524dRamon y Cajal\u7684\u5f00\u521b\u6027\u7814\u7a76\u4ee5\u6765\uff0c\u4eba\u4eec\u5df2\u8ba4\u8bc6\u5230\u6210\u4eba\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf (CNS) \u4e25\u91cd\u635f\u4f24\u7684\u8f74\u7a81\u65e0\u6cd5\u81ea\u53d1\u518d\u751f\uff0c\u8fd9\u5e38\u5e38\u5bfc\u81f4\u6c38\u4e45\u6027\u529f\u80fd\u969c\u788d\uff0c\u5305\u62ec\u635f\u4f24\u5e73\u9762\u4ee5\u4e0b\u7684\u8fd0\u52a8\u3001\u611f\u89c9\u548c\u81ea\u4e3b\u795e\u7ecf\u529f\u80fd\u3002<\/p>\n<p>\u76ee\u524d\u5c1a\u65e0\u83b7\u6279\u7684\u4e34\u5e8a\u6cbb\u7597\u65b9\u6cd5\uff0c\u53ef\u7528\u4e8e\u6025\u6027\u4fdd\u62a4\u810a\u9ad3\u635f\u4f24\u540e\u7684\u795e\u7ecf\u5143\u548c\u8f74\u7a81\u6216\u4fc3\u8fdb\u5176\u518d\u751f\uff0c\u8fd9\u662f\u4e00\u4e2a\u5de8\u5927\u7684\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201737-68d3e1612aad5.png\" alt=\"\" title=\"\"><figcaption><\/figcaption><\/figure>\n<p>\u795e\u7ecf\u5e72\u7ec6\u80de\u7814\u7a76\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4e3a\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u7684\u6f5c\u5728\u6cbb\u7597\u65b9\u6cd5\u5f00\u8f9f\u4e86\u65b0\u7684\u9014\u5f84\u3002\u901a\u5e38\uff0c\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u4e3a\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u7684\u6cbb\u7597\u63d0\u4f9b\u4e86\u4e09\u79cd\u6f5c\u5728\u673a\u5236\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li>(1) \u901a\u8fc7\u79fb\u690d\u5206\u5316\u4e3a\u4e2d\u95f4\u795e\u7ecf\u5143\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSC\uff09\u6765\u201c\u91cd\u65b0\u8fde\u63a5\u201d\u53d7\u635f\u7684\u8f74\u7a81\u901a\u8def\uff0c\u8fd9\u4e9b\u4e2d\u95f4\u795e\u7ecf\u5143\u53ef\u5728\u635f\u4f24\u90e8\u4f4d\u5145\u5f53\u795e\u7ecf\u5143\u7684\u4e2d\u7ee7\uff1b<\/li>\n<li>(2) \u901a\u8fc7\u79fb\u690dNSC\u884d\u751f\u7684\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u524d\u4f53\u7ec6\u80de\uff08OPC\uff09\uff0c\u4f7f\u635f\u4f24\u90e8\u4f4d\u5468\u56f4\u5269\u4f59\u7684\u5bbf\u4e3b\u8f74\u7a81\u8fdb\u884c\u9ad3\u9798\u518d\u751f\uff1b<\/li>\n<li>(3) \u5982\u679c\u5728\u635f\u4f24\u540e\u8db3\u591f\u65e9\u5730\u6ce8\u5c04NSC\uff0c\u5219\u53ef\u4ee5\u63d0\u4f9b\u795e\u7ecf\u4fdd\u62a4\u3002<\/li>\n<\/ul>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%EF%BC%9A2025%E4%BF%AE%E5%A4%8D%E6%9C%BA%E5%88%B6%E8%A7%A3%E6%9E%90%E3%80%81%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%E7%AA%81%E7%A0%B4%E4%B8%8E%E8%BD%AC%E5%8C%96%E5%89%8D%E6%99%AF\" >\u0632\u0631\u0627\u0639\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629 \u0644\u0625\u0635\u0627\u0628\u0627\u062a \u0627\u0644\u062d\u0628\u0644 \u0627\u0644\u0634\u0648\u0643\u064a: \u062a\u062d\u0644\u064a\u0644 \u0622\u0644\u064a\u0627\u062a \u0627\u0644\u0625\u0635\u0644\u0627\u062d\u060c \u0648\u0627\u062e\u062a\u0631\u0627\u0642\u0627\u062a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0627\u0644\u0622\u0641\u0627\u0642 \u0627\u0644\u0627\u0646\u062a\u0642\u0627\u0644\u064a\u0629 \u0641\u064a \u0639\u0627\u0645 2025<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88NSC%EF%BC%89%E7%9A%84%E5%88%86%E7%A6%BB%E5%92%8C%E7%89%B9%E6%80%A7\" >\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSC\uff09\u7684\u5206\u79bb\u548c\u7279\u6027<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E7%9A%84%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E4%BB%8E%E5%93%AA%E9%87%8C%E6%9D%A5%EF%BC%9F\" >\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\u4ece\u54ea\u91cc\u6765\uff1f<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#01%E3%80%81%E4%BB%8E%E5%8F%91%E8%82%B2%E4%B8%AD%E8%84%8A%E9%AB%93%E7%9B%B4%E6%8E%A5%E5%88%86%E7%A6%BB%E7%9A%84%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E\" >01\u3001\u4ece\u53d1\u80b2\u4e2d\u810a\u9ad3\u76f4\u63a5\u5206\u79bb\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#02%E3%80%81%E8%83%9A%E8%83%8E%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88ESC%EF%BC%89%E5%90%91%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E8%BD%AC%E5%8C%96\" >02\u3001\u80da\u80ce\u5e72\u7ec6\u80de\uff08ESC\uff09\u5411\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u8f6c\u5316<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#03%E3%80%81%E8%AF%B1%E5%AF%BC%E6%80%A7%E5%A4%9A%E8%83%BD%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88iPSC%EF%BC%89%E5%90%91%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E8%BD%AC%E5%8C%96\" >03\u3001\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\u5411\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u8f6c\u5316<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#04%E3%80%81%E4%BD%93%E7%BB%86%E8%83%9E%E7%9B%B4%E6%8E%A5%E5%88%86%E5%8C%96%E4%B8%BA%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E\" >04\u3001\u4f53\u7ec6\u80de\u76f4\u63a5\u5206\u5316\u4e3a\u795e\u7ecf\u5e72\u7ec6\u80de<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#%E4%BD%93%E5%86%85%E7%A0%94%E7%A9%B6%E5%8F%91%E7%8E%B0%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E7%9A%84%E4%B8%89%E5%A4%A7%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\" >\u4f53\u5185\u7814\u7a76\u53d1\u73b0\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u4e09\u5927\u4f5c\u7528\u673a\u5236<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\" >\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#1_%E8%83%9A%E8%83%8E%E5%B9%B2%E7%BB%86%E8%83%9E%E8%A1%8D%E7%94%9F%E7%9A%84%E5%B0%91%E7%AA%81%E8%83%B6%E8%B4%A8%E7%BB%86%E8%83%9E%E7%A5%96%E7%BB%86%E8%83%9E%EF%BC%88OPC%EF%BC%89%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\" >1. \u80da\u80ce\u5e72\u7ec6\u80de\u884d\u751f\u7684\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u7956\u7ec6\u80de\uff08OPC\uff09\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#2_%E8%83%8E%E5%84%BF%E8%84%91%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88HuCNS-SC%C2%AE%EF%BC%89%E7%9A%84%E7%A0%94%E7%A9%B6%E4%B8%8E%E7%BB%88%E6%AD%A2\" >2. \u80ce\u513f\u8111\u795e\u7ecf\u5e72\u7ec6\u80de\uff08HuCNS-SC\u00ae\uff09\u7684\u7814\u7a76\u4e0e\u7ec8\u6b62<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#3_%E8%83%8E%E5%84%BF%E8%84%8A%E9%AB%93%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88NSI-566%EF%BC%89%E5%8F%8A%E5%85%B6%E4%BB%96%E8%BF%9B%E8%A1%8C%E4%B8%AD%E8%AF%95%E9%AA%8C\" >3. \u80ce\u513f\u810a\u9ad3\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSI-566\uff09\u53ca\u5176\u4ed6\u8fdb\u884c\u4e2d\u8bd5\u9a8c<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#4_%E5%85%B1%E5%90%8C%E6%8C%91%E6%88%98%E4%B8%8E%E6%9C%AA%E6%9D%A5%E6%96%B9%E5%90%91\" >4. \u5171\u540c\u6311\u6218\u4e0e\u672a\u6765\u65b9\u5411<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E7%9A%84%E6%9C%AA%E6%9D%A5%E5%B1%95%E6%9C%9B\" >\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u672a\u6765\u5c55\u671b<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19245.html\/#%E5%A2%9E%E6%95%88%E6%8A%80%E6%9C%AF%E4%B8%8E%E5%8D%8F%E5%90%8C%E6%8C%91%E6%88%98%EF%BC%9A%E8%BF%9B%E4%B8%80%E6%AD%A5%E5%A2%9E%E6%95%88%E7%AD%96%E7%95%A5%E5%8C%85%E6%8B%AC%EF%BC%9A\" >\u589e\u6548\u6280\u672f\u4e0e\u534f\u540c\u6311\u6218\uff1a\u8fdb\u4e00\u6b65\u589e\u6548\u7b56\u7565\u5305\u62ec\uff1a<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%EF%BC%9A2025%E4%BF%AE%E5%A4%8D%E6%9C%BA%E5%88%B6%E8%A7%A3%E6%9E%90%E3%80%81%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%E7%AA%81%E7%A0%B4%E4%B8%8E%E8%BD%AC%E5%8C%96%E5%89%8D%E6%99%AF\"><\/span><strong>\u0632\u0631\u0627\u0639\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629 \u0644\u0625\u0635\u0627\u0628\u0627\u062a \u0627\u0644\u062d\u0628\u0644 \u0627\u0644\u0634\u0648\u0643\u064a: \u062a\u062d\u0644\u064a\u0644 \u0622\u0644\u064a\u0627\u062a \u0627\u0644\u0625\u0635\u0644\u0627\u062d\u060c \u0648\u0627\u062e\u062a\u0631\u0627\u0642\u0627\u062a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0627\u0644\u0622\u0641\u0627\u0642 \u0627\u0644\u0627\u0646\u062a\u0642\u0627\u0644\u064a\u0629 \u0641\u064a \u0639\u0627\u0645 2025<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>2025\u5e747\u67082\u53f7\uff0c\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u795e\u7ecf\u79d1\u5b66\u7cfb\u5728\u56fd\u9645\u6743\u5a01\u671f\u520a\u6742\u5fd7\u300a<a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-3-031-89307-0_14\" target=\"_blank\" rel=\"nofollow noopener\">Translational Neuroscience<\/a>\u300b\u53d1\u8868\u4e86\u4e00\u7bc7\u201c\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u201d\u7684\u6587\u732e\u7efc\u8ff0\u3002<sup>[1]<\/sup><\/p>\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201737-68d3e1618e939.jpg\" alt=\"\" title=\"\"><\/figure>\n<p>\u8be5\u7efc\u8ff0\u7814\u7a76\u8868\u660e\uff1a<strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u6216\u795e\u7ecf\u7956\u7ec6\u80de (NPC) \u79fb\u690d\u5230\u4e25\u91cd\u810a\u9ad3\u635f\u4f24 (SCI) \u90e8\u4f4d\u540e\u80fd\u591f\u5b58\u6d3b\uff0c\u5206\u5316\u4e3a\u795e\u7ecf\u5143\u548c\u795e\u7ecf\u80f6\u8d28\u7ec6\u80de\uff0c\u5e76\u5ef6\u4f38\u51fa\u5927\u91cf\u8f74\u7a81\uff0c\u5ef6\u4f38\u81f3\u76f8\u5f53\u957f\u7684\u8ddd\u79bb\uff0c\u4ee5\u4fbf\u4e0e\u635f\u4f24\u90e8\u4f4d\u4e0b\u65b9\u7684\u5bbf\u4e3b\u795e\u7ecf\u5143\u5efa\u7acb\u8fde\u63a5<\/strong>\u3002\u53cd\u8fc7\u6765\uff0c\u5bbf\u4e3b\u7684\u8f74\u7a81\u4f1a\u518d\u751f\u5230NSC\/NPC\u79fb\u690d\u7269\u4e2d\uff0c\u5e76\u4e0e\u79fb\u690d\u7269\u6765\u6e90\u7684\u795e\u7ecf\u5143\u5f62\u6210\u7a81\u89e6\u8fde\u63a5\u3002<\/p>\n<p>\u56e0\u6b64\uff0cNSC\/NPC\u79fb\u690d\u7269\u6765\u6e90\u7684\u795e\u7ecf\u5143\u53ef\u4ee5\u4f5c\u4e3a\u795e\u7ecf\u5143\u4e2d\u7ee7\uff0c\u91cd\u5efa\u635f\u4f24\u90e8\u4f4d\u7684\u795e\u7ecf\u4f20\u9012\uff0c\u5373\u4f7f\u5728\u4e25\u91cdSCI\u540e\u4e5f\u80fd\u6539\u5584\u529f\u80fd\u7ed3\u5c40\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88NSC%EF%BC%89%E7%9A%84%E5%88%86%E7%A6%BB%E5%92%8C%E7%89%B9%E6%80%A7\"><\/span><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSC\uff09\u7684\u5206\u79bb\u548c\u7279\u6027<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u5b9a\u4e49\u3001\u8d77\u6e90\u4e0e\u57fa\u672c\u7279\u6027\uff1a<\/strong>\u795e\u7ecf\u5e72\u7ec6\u80de (NSC) \u662f\u795e\u7ecf\u7cfb\u7edf\u7684\u65e9\u671f\u5e72\u7ec6\u80de\uff0c\u5177\u6709\u81ea\u6211\u66f4\u65b0\u80fd\u529b\uff0c\u53ef\u5206\u5316\u4e3a\u795e\u7ecf\u5143\u548c\u795e\u7ecf\u80f6\u8d28\u7ec6\u80de\uff08\u56fe1\uff09\u3002\u5b83\u4eec\u4e3b\u8981\u6765\u6e90\u4e8e\u80da\u80ce\u5e72\u7ec6\u80de\uff08\u5b58\u5728\u4e8e\u56ca\u80da\u5185\u7ec6\u80de\u56e2\uff09\uff0c\u5728\u7279\u5b9a\u8f6c\u5f55\u56e0\u5b50\u4f5c\u7528\u4e0b\uff0c\u5916\u80da\u5c42\u7684\u4e00\u90e8\u5206\u80da\u80ce\u5e72\u7ec6\u80de\u4f1a\u5206\u5316\u4e3a\u591a\u80fd\u795e\u7ecf\u5e72\u7ec6\u80de\uff0c\u5b9a\u4f4d\u4e8e\u795e\u7ecf\u7ba1\u3002NSC\u5728\u53d1\u80b2\u8fc7\u7a0b\u4e2d\u5b58\u5728\u65f6\u95f4\u56e0\u7269\u79cd\u800c\u5f02\uff0c\u4f1a\u5feb\u901f\u6269\u589e\u5e76\u6784\u5efa\u539f\u59cb\u795e\u7ecf\u7cfb\u7edf\u3002<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 695px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201737-68d3e1619bed9.png\" alt=\"\u56fe1\uff1a\u80da\u80ce\u5e72\u7ec6\u80de\u548c\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u53d1\u80b2\u9636\u6bb5\u3002\u6240\u6709\u5e72\u7ec6\u80de\u90fd\u5177\u6709\u5206\u88c2\u548c\u81ea\u6211\u66f4\u65b0\u7684\u80fd\u529b\uff1b\u5b50\u7ec6\u80de\u53ef\u4ee5\u5206\u5316\u6210\u7279\u5b9a\u7684\u8c31\u7cfb\uff0c\u5305\u62ec\u795e\u7ecf\u5e72\u7ec6\u80de\u3001\u795e\u7ecf\u7956\u7ec6\u80de\uff0c\u8fdb\u800c\u5206\u5316\u6210\u795e\u7ecf\u5143\u548c\u795e\u7ecf\u80f6\u8d28\u7ec6\u80de\u3002\" width=\"685\" height=\"716\" title=\"\"><p class=\"wp-caption-text\">\u56fe1\uff1a\u80da\u80ce\u5e72\u7ec6\u80de\u548c\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u53d1\u80b2\u9636\u6bb5\u3002\u6240\u6709\u5e72\u7ec6\u80de\u90fd\u5177\u6709\u5206\u88c2\u548c\u81ea\u6211\u66f4\u65b0\u7684\u80fd\u529b\uff1b\u5b50\u7ec6\u80de\u53ef\u4ee5\u5206\u5316\u6210\u7279\u5b9a\u7684\u8c31\u7cfb\uff0c\u5305\u62ec\u795e\u7ecf\u5e72\u7ec6\u80de\u3001\u795e\u7ecf\u7956\u7ec6\u80de\uff0c\u8fdb\u800c\u5206\u5316\u6210\u795e\u7ecf\u5143\u548c\u795e\u7ecf\u80f6\u8d28\u7ec6\u80de\u3002<\/p><\/div><figcaption><\/figcaption><\/figure>\n<p><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u5206\u5316\u8def\u5f84\u4e0e\u7279\u6b8a\u7c7b\u578b\uff1a<\/strong>\u7ecf\u5386\u591a\u6b21\u5206\u88c2\u540e\uff0cNSC\u8fdb\u5165\u4e2d\u95f4\u9636\u6bb5\u6210\u4e3a\u795e\u7ecf\u7956\u7ec6\u80de\uff0c\u5176\u81ea\u6211\u66f4\u65b0\u80fd\u529b\u53d7\u9650\u3002\u8fd9\u4e9b\u7956\u7ec6\u80de\u5206\u5316\u4e3a\u4e24\u79cd\u9650\u5236\u6027\u524d\u4f53\uff1a\u795e\u7ecf\u5143\u9650\u5236\u6027\u7956\u7ec6\u80de\uff08\u53ea\u4ea7\u751f\u795e\u7ecf\u5143\uff09\u548c\u795e\u7ecf\u80f6\u8d28\u7ec6\u80de\u9650\u5236\u6027\u7956\u7ec6\u80de\uff08\u53ea\u4ea7\u751f\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\u548c\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\uff09\u3002<\/p>\n<p>\u6700\u7ec8\uff0c\u8fd9\u4e9b\u524d\u4f53\u7ec6\u80de\u505c\u6b62\u5206\u88c2\uff0c\u6210\u719f\u4e3a\u7279\u5b9a\u7ec6\u80de\u7c7b\u578b\u3002\u6b64\u5916\uff0c\u80da\u80ce\u5c3e\u90e8\u5b58\u5728\u4e00\u79cd\u72ec\u7279\u7684\u53cc\u80fd\u7956\u7ec6\u80de\u2014\u2014\u795e\u7ecf\u4e2d\u80da\u5c42\u7956\u7ec6\u80de\uff08NMP\uff09\uff0c\u53ef\u540c\u65f6\u5206\u5316\u4e3a\u795e\u7ecf\u8c31\u7cfb\uff08\u5982\u810a\u9ad3\u7956\u7ec6\u80de\u3001\u795e\u7ecf\u5d74\u7ec6\u80de\uff09\u548c\u4e2d\u80da\u5c42\u8c31\u7cfb\u3002<\/p>\n<p><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u5728\u75be\u75c5\u6cbb\u7597\u4e2d\u7684\u5e94\u7528\u6f5c\u529b\uff1a<\/strong>\u76ee\u524d\u5df2\u6709\u6210\u719f\u65b9\u6848\u53ef\u8bf1\u5bfc\u57f9\u517b\u7684NSC\u5206\u5316\u4e3a\u7279\u5b9a\u529f\u80fd\u7684\u6210\u719f\u7ec6\u80de\u7c7b\u578b\u7528\u4e8e\u7ec6\u80de\u66ff\u4ee3\u6cbb\u7597\u3002\u4f8b\u5982\uff0c\u53ef\u8bf1\u5bfc\u4ea7\u751f\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u3001\u7eb9\u72b6\u4f53\u4e2d\u95f4\u795e\u7ecf\u5143\u6cbb\u7597\u4ea8\u5ef7\u987f\u821e\u8e48\u75c7\u3001\u76ae\u5c42\u795e\u7ecf\u5143\u6cbb\u7597\u4e2d\u98ce\u3002<\/p>\n<p>NSC\u4e5f\u53ef\u88ab\u8bf1\u5bfc\u5206\u5316\u4e3a\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\uff0c\u7528\u4e8e\u6cbb\u7597\u9ad3\u9798\u5f62\u6210\u969c\u788d\u6027\u75be\u75c5\u3002\u4e00\u4e9b\u57fa\u4e8eNSC\u7684\u6cbb\u7597\u7b56\u7565\uff08\u5982\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\uff09\u5df2\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002<\/p>\n<p><strong>\u9488\u5bf9\u810a\u9ad3\u635f\u4f24\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u7b56\u7565\uff1a<\/strong>\u5728\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u6cbb\u7597\u4e2d\uff0c\u4e3b\u8981\u63a2\u7d22\u4e24\u79cdNSC\u7b56\u7565\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li>\u4e00\u662f\u79fb\u690d\u591a\u80fdNSC\uff0c\u671f\u671b\u5176\u5728\u635f\u4f24\u90e8\u4f4d\u5206\u5316\u5e76\u66ff\u4ee3\u795e\u7ecf\u5143\u3001\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\u548c\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\uff0c\u5f62\u6210\u65b0\u7684\u795e\u7ecf\u8fde\u63a5\uff1b<\/li>\n<li>\u4e8c\u662f\u79fb\u690d\u5df2\u5b9a\u5411\u5206\u5316\u7684\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u7956\u7ec6\u80de\uff0c\u65e8\u5728\u4e3a\u6b8b\u7559\u7684\u5bbf\u4e3b\u8f74\u7a81\u91cd\u65b0\u5f62\u6210\u9ad3\u9798\u4ee5\u6062\u590d\u90e8\u5206\u529f\u80fd\u3002<\/li>\n<\/ul>\n<p>\u7b2c\u4e09\u79cd\u6f5c\u5728\u673a\u5236\u662f\u79fb\u690d\u7ec6\u80de\u5206\u6ccc\u795e\u7ecf\u4fdd\u62a4\u56e0\u5b50\uff08\u5982\u751f\u957f\u56e0\u5b50\uff09\uff0c\u5728\u635f\u4f24\u65e9\u671f\u8d77\u4fdd\u62a4\u4f5c\u7528\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E7%9A%84%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E4%BB%8E%E5%93%AA%E9%87%8C%E6%9D%A5%EF%BC%9F\"><\/span>\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\u4ece\u54ea\u91cc\u6765\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u591a\u6837\u5316\u6765\u6e90\uff1a<\/strong>\u65e9\u671f\u7814\u7a76\u4e3b\u8981\u4f7f\u7528\u6765\u81ea\u53d1\u80b2\u4e2d\u810a\u9ad3\u6216\u8111\u7684NSC\u6216\u7ec4\u7ec7\u3002\u5982\u4eca\uff0cNSC\u53ca\u5176\u884d\u751f\u7269\u6709\u4e86\u66f4\u5e7f\u6cdb\u7684\u66ff\u4ee3\u6765\u6e90\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li>(1) \u76f4\u63a5\u4ece\u80da\u80ce\u5e72\u7ec6\u80de\u5206\u5316\u800c\u6765\uff1b<\/li>\n<li>(2) \u6765\u81ea\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff0c\u7531\u6210\u719f\u4f53\u7ec6\u80de\u7ecf\u91cd\u7f16\u7a0b\u83b7\u5f97\uff09\uff1b<\/li>\n<li>(3) \u4f7f\u7528\u7279\u5b9a\u8f6c\u5f55\u56e0\u5b50\u7ec4\u5408\u5c06\u4f53\u7ec6\u80de\u76f4\u63a5\u91cd\u7f16\u7a0b\u4e3aNSC\u3002<\/li>\n<\/ul>\n<p>\u8fd9\u4e9b\u4e0d\u540c\u6765\u6e90\u4e3a\u7814\u7a76\u548c\u6cbb\u7597\u63d0\u4f9b\u4e86\u66f4\u591a\u9009\u62e9\uff0c\u4e0b\u6587\u5c06\u5bf9\u8fd9\u4e9b\u7ec6\u80de\u6765\u6e90\u8fdb\u884c\u66f4\u8be6\u7ec6\u7684\u4ecb\u7ecd\u3002<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 1578px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201737-68d3e161b2f14.jpg\" alt=\"\u88681\uff1a\u795e\u7ecf\u5e72\u7ec6\u80de\u548c\u795e\u7ecf\u7956\u7ec6\u80de\u7684\u6765\u6e90\" width=\"1568\" height=\"220\" title=\"\"><p class=\"wp-caption-text\">\u88681\uff1a\u795e\u7ecf\u5e72\u7ec6\u80de\u548c\u795e\u7ecf\u7956\u7ec6\u80de\u7684\u6765\u6e90<\/p><\/div><figcaption><\/figcaption><\/figure>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"01%E3%80%81%E4%BB%8E%E5%8F%91%E8%82%B2%E4%B8%AD%E8%84%8A%E9%AB%93%E7%9B%B4%E6%8E%A5%E5%88%86%E7%A6%BB%E7%9A%84%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E\"><\/span><strong>01\u3001\u4ece\u53d1\u80b2\u4e2d\u810a\u9ad3\u76f4\u63a5\u5206\u79bb\u7684\u795e\u7ecf\u5e72\u7ec6\u80de<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u5728\u556e\u9f7f\u52a8\u7269\u80da\u80ce\u53d1\u80b2\u7684\u7b2c11\u81f318\u5929\u6216\u4eba\u7c7b\u80da\u80ce\u53d1\u80b2\u7684\u7b2c8\u81f310\u5468\uff0c\u53ef\u4ee5\u76f4\u63a5\u4ece\u53d1\u80b2\u4e2d\u7684\u810a\u9ad3\u5206\u79bb\u51fa\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSC\uff09\u548c\u6b63\u5728\u5411\u795e\u7ecf\u5143\u6216\u80f6\u8d28\u7ec6\u80de\u5b9a\u5411\u5206\u5316\u7684\u7956\u7ec6\u80de\u3002<\/p>\n<p>\u8fd9\u7c7b\u7ec6\u80de\u7684\u5173\u952e\u4f18\u52bf\u5728\u4e8e\u5176\u5177\u6709\u810a\u9ad3\u7279\u5f02\u6027\u7684\u7ec6\u80de\u547d\u8fd0\uff0c\u5373\u503e\u5411\u4e8e\u5206\u5316\u4e3a\u9002\u5408\u810a\u9ad3\u73af\u5883\u7684\u7ec6\u80de\u7c7b\u578b\uff08\u5982\u810a\u9ad3\u5174\u594b\u6027\u4e2d\u95f4\u795e\u7ecf\u5143\uff09\uff0c\u8fd9\u5bf9\u4e8e\u5728\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u90e8\u4f4d\u91cd\u5efa\u529f\u80fd\u6027\u795e\u7ecf\u7a81\u89e6\u4e2d\u7ee7\u81f3\u5173\u91cd\u8981\u3002\u57fa\u4e8e\u6b64\u4f18\u52bf\uff0c\u8fd9\u7c7b\u6e90\u81ea\u53d1\u80b2\u4e2d\u810a\u9ad3\u7684NSC\u5df2\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7528\u4e8e\u6cbb\u7597\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff08ALS\uff09\u548c\u810a\u9ad3\u635f\u4f24\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"02%E3%80%81%E8%83%9A%E8%83%8E%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88ESC%EF%BC%89%E5%90%91%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E8%BD%AC%E5%8C%96\"><\/span><strong>02\u3001\u80da\u80ce\u5e72\u7ec6\u80de\uff08ESC\uff09\u5411\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u8f6c\u5316<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u80da\u80ce\u5e72\u7ec6\u80de\uff08\u6e90\u81ea\u56ca\u80da\u5185\u7ec6\u80de\u56e2\uff09\u5177\u6709\u5206\u5316\u4e3a\u5305\u62ec\u795e\u7ecf\u5e72\u7ec6\u80de\u5728\u5185\u51e0\u4e4e\u6240\u6709\u7ec6\u80de\u7c7b\u578b\u7684\u6f5c\u529b\u3002\u867d\u7136\u4eba\u7c7b\u548c\u5c0f\u9f20ESC\u7cfb\u4e30\u5bcc\uff0c\u4f46\u5e38\u7528SCI\u6a21\u578b\u5927\u9f20\u7684ESC\u7cfb\u5374\u76f8\u5bf9\u7a00\u5c11\u3002<\/p>\n<p>\u5229\u7528ESC\u53ef\u4ee5\u751f\u6210\u7528\u4e8e\u6cbb\u7597\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\u53ca\u5176\u884d\u751f\u7269\uff1a\u65e9\u671f\u7814\u7a76\u66fe\u751f\u6210\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u7956\u7ec6\u80de\uff08OPC\uff09\u7528\u4e8e\u8f74\u7a81\u9ad3\u9798\u518d\u751f\uff0c\u73b0\u5728\u4e5f\u80fd\u751f\u6210NSC\u7528\u4e8e\u795e\u7ecf\u5143\u548c\u80f6\u8d28\u7ec6\u80de\u7684\u66ff\u4ee3\u6cbb\u7597\u3002\u7279\u522b\u662f\uff0c\u8fd1\u671f\u6280\u672f\u5df2\u80fd\u7a33\u5b9a\u5730\u4ece\u4eba\u7c7bESC\u751f\u6210\u5e76\u5728\u4f53\u5916\u957f\u671f\u7ef4\u6301\u5177\u6709\u810a\u9ad3\u7279\u6027\u7684NSC\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"03%E3%80%81%E8%AF%B1%E5%AF%BC%E6%80%A7%E5%A4%9A%E8%83%BD%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88iPSC%EF%BC%89%E5%90%91%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E8%BD%AC%E5%8C%96\"><\/span><strong>03\u3001\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\u5411\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u8f6c\u5316<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>2006\u5e74\uff0c\u5c71\u4e2d\u4f38\u5f25\u56e2\u961f\u9996\u6b21\u901a\u8fc7\u7279\u5b9a\u8f6c\u5f55\u56e0\u5b50\u91cd\u7f16\u7a0b\u5c06\u6210\u4f53\u7ec6\u80de\uff08\u5982\u6210\u7ea4\u7ef4\u7ec6\u80de\uff09\u8f6c\u5316\u4e3a\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\u3002\u968f\u540e\u8bc1\u5b9eiPSC\u4e5f\u80fd\u5206\u5316\u4e3a\u795e\u7ecf\u5e72\u7ec6\u80de\uff0c\u8fd9\u4e3a\u5229\u7528\u60a3\u8005\u81ea\u4f53\u7ec6\u80de\u6765\u6e90\u7684\u795e\u7ecf\u5143\u548c\u80f6\u8d28\u7ec6\u80de\u4fee\u590d\u795e\u7ecf\u7cfb\u7edf\u635f\u4f24\u5e26\u6765\u4e86\u5de8\u5927\u5e0c\u671b\u3002<\/p>\n<p>\u76ee\u524d\uff0c\u5c06iPSC\u8bf1\u5bfc\u4e3aNSC\u8fdb\u884c\u81ea\u4f53\u79fb\u690d\u7684\u7b56\u7565\u5df2\u5728\u65e5\u672c\u8fdb\u5165\u9488\u5bf9\u810a\u9ad3\u635f\u4f24\u548c\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff08ALS\uff09\u7684\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"04%E3%80%81%E4%BD%93%E7%BB%86%E8%83%9E%E7%9B%B4%E6%8E%A5%E5%88%86%E5%8C%96%E4%B8%BA%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E\"><\/span><strong>04\u3001\u4f53\u7ec6\u80de\u76f4\u63a5\u5206\u5316\u4e3a\u795e\u7ecf\u5e72\u7ec6\u80de<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u8fd1\u671f\uff0c\u5df2\u5f00\u53d1\u51fa\u53ef\u76f4\u63a5\u9a71\u52a8\u6210\u719f\uff08\u751a\u81f3\u201c\u6709\u4e1d\u5206\u88c2\u540e\u201d\uff09\u4f53\u7ec6\u80de\u7c7b\u578b\u5206\u5316\u4e3a\u5176\u4ed6\u7ec6\u80de\u7c7b\u578b\u7684\u6280\u672f\u3002<\/p>\n<p><strong>\u76f4\u63a5\u91cd\u7f16\u7a0b\u7684\u6838\u5fc3\u6280\u672f\u4e0e\u8fc7\u7a0b\uff1a<\/strong>\u4f53\u7ec6\u80de\uff08\u5982\u6210\u7ea4\u7ef4\u7ec6\u80de\u3001\u9020\u8840\u7ec6\u80de\uff09\u65e0\u9700\u5148\u9006\u8f6c\u4e3a\u591a\u80fd\u5e72\u7ec6\u80de\u72b6\u6001\uff0c\u53ef\u901a\u8fc7\u7279\u5b9a\u8f6c\u5f55\u56e0\u5b50\u7ec4\u5408\uff08\u5982Sox2\u3001Klf4\u3001c-Myc\u3001Brn2\u3001Brn4\u3001E47\/Tcf3\u3001FoxG1\uff09\u8fdb\u884c\u76f4\u63a5\u91cd\u7f16\u7a0b\uff0c\u8f6c\u5316\u4e3a\u795e\u7ecf\u5e72\u7ec6\u80de (NSC) \u751a\u81f3\u6210\u719f\u795e\u7ecf\u5143\u3002\u8be5\u8fc7\u7a0b\u901a\u5e38\u4ece\u6613\u4e8e\u83b7\u53d6\u7684\u4f53\u7ec6\u80de\uff08\u5982\u76ae\u80a4\u6d3b\u68c0\u6765\u6e90\u7684\u6210\u7ea4\u7ef4\u7ec6\u80de\uff09\u5f00\u59cb\uff0c\u5728\u4f53\u5916\u57f9\u517b\u4f53\u7cfb\u4e2d\u8bf1\u5bfc\u5176\u8868\u8fbe\u8fd9\u4e9b\u5173\u952e\u8f6c\u5f55\u56e0\u5b50\u3002\u901a\u8fc7\u7cbe\u786e\u4f18\u5316\u7ec6\u80de\u57f9\u517b\u57fa\u8d28\u3001\u6dfb\u52a0\u5fc5\u8981\u7684\u751f\u957f\u56e0\u5b50\u548c\u5c0f\u5206\u5b50\u5316\u5408\u7269\uff0c\u5e76\u7ecf\u8fc7\u4e00\u6bb5\u65f6\u95f4\u7684\u4f53\u5916\u57f9\u517b\uff08\u901a\u5e38\u4e3a1\u81f32\u4e2a\u6708\uff09\uff0c\u6700\u7ec8\u53ef\u83b7\u5f97\u5177\u6709\u795e\u7ecf\u5e72\u7ec6\u80de\u7279\u6027\u7684\u7ec6\u80de\u7fa4\u4f53\u3002<\/p>\n<p><strong>\u4f18\u52bf\u3001\u5e94\u7528\u4e0e\u524d\u666f\uff1a<\/strong>\u8fd9\u79cd\u76f4\u63a5\u91cd\u7f16\u7a0b\u6280\u672f\u4ea7\u751f\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\uff08\u6709\u65f6\u79f0\u4e3a\u8bf1\u5bfc\u6027\u795e\u7ecf\u5e72\u7ec6\u80de\uff0ciNSC\uff09\uff0c\u4e0e\u80da\u80ce\u5e72\u7ec6\u80de (ESC) \u6216\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de (iPSC) \u884d\u751f\u7684NSC\u4ee5\u53ca\u6e90\u81ea\u53d1\u80b2\u4e2d\u810a\u9ad3\u7684\u795e\u7ecf\u7956\u7ec6\u80de\u4e00\u6837\uff0c\u90fd\u662f\u810a\u9ad3\u635f\u4f24\u7b49\u75be\u75c5\u7ec6\u80de\u6cbb\u7597\u7684\u6f5c\u5728\u6765\u6e90\u3002\u5176\u663e\u8457\u4f18\u52bf\u5728\u4e8e\u907f\u514d\u4e86\u591a\u80fd\u5e72\u7ec6\u80de\u9636\u6bb5\uff0c\u53ef\u80fd\u7f29\u77ed\u65f6\u95f4\u5e76\u964d\u4f4e\u81f4\u7624\u98ce\u9669\uff0c\u540c\u65f6\u5177\u5907\u81ea\u4f53\u79fb\u690d\u6f5c\u529b\uff08\u5c24\u5176\u5f53\u4f7f\u7528\u60a3\u8005\u81ea\u8eab\u4f53\u7ec6\u80de\u65f6\uff09\u3002<\/p>\n<p>\u867d\u7136\u8fd9\u4e9b\u4e0d\u540c\u6765\u6e90\u7684NSC\u5728\u7279\u6027\u3001\u8868\u89c2\u9057\u4f20\u5370\u8bb0\u3001\u5b89\u5168\u6027\uff08\u5982\u67d3\u8272\u4f53\u7a33\u5b9a\u6027\uff09\u548c\u6700\u7ec8\u5206\u5316\u6f5c\u80fd\u4e0a\u4ecd\u9700\u6df1\u5165\u7814\u7a76\uff0c\u4f46\u8be5\u6280\u672f\u4e3a\u83b7\u5f97\u60a3\u8005\u7279\u5f02\u6027\u795e\u7ecf\u5e72\u7ec6\u80de\u7528\u4e8e\u4fee\u590d\uff08\u5982\u5206\u5316\u4e3a\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u524d\u4f53\u4ee5\u4fc3\u8fdb\u9ad3\u9798\u518d\u751f\uff09\u63d0\u4f9b\u4e86\u65b0\u7684\u91cd\u8981\u9014\u5f84\uff0c\u76f8\u5173\u4e34\u5e8a\u5e94\u7528\u6b63\u5728\u63a2\u7d22\u4e2d\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%BD%93%E5%86%85%E7%A0%94%E7%A9%B6%E5%8F%91%E7%8E%B0%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E7%9A%84%E4%B8%89%E5%A4%A7%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\"><\/span>\u4f53\u5185\u7814\u7a76\u53d1\u73b0\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u4e09\u5927\u4f5c\u7528\u673a\u5236<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>1.\u795e\u7ecf\u4fdd\u62a4\u673a\u5236\uff1a<\/strong>\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSC\uff09\u79fb\u690d\u540e\u53ef\u901a\u8fc7\u5206\u6ccc\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff08\u5982VEGF\u3001FGF-2\uff09\u548c\u8c03\u8282\u514d\u75ab\u5fae\u73af\u5883\u53d1\u6325\u795e\u7ecf\u4fdd\u62a4\u4f5c\u7528\u3002\u7814\u7a76\u8868\u660e\uff0c\u79fb\u690d\u7684NSC\u80fd\u5728\u635f\u4f24\u65e9\u671f\uff08\u5982\u4f24\u540e10\u5929\u5185\uff09\u8c03\u8282\u514d\u75ab\u7ec6\u80de\u56e0\u5b50\uff08\u5982IL-1\u03b1\u3001IL-6\u3001IL-10\uff09\uff0c\u964d\u4f4e\u708e\u75c7\u53cd\u5e94\u548c\u7ec6\u80de\u6b7b\u4ea1\uff0c\u4fc3\u8fdb\u8840\u7ba1\u751f\u6210\uff0c\u4ece\u800c\u4fdd\u62a4\u6b8b\u7559\u7684\u810a\u9ad3\u7ec4\u7ec7\u5e76\u7f29\u5c0f\u635f\u4f24\u8303\u56f4\u3002\u8fd9\u79cd\u4fdd\u62a4\u4f5c\u7528\u4e3a\u540e\u7eed\u4fee\u590d\u521b\u9020\u4e86\u66f4\u6709\u5229\u7684\u5fae\u73af\u5883\u3002<\/p>\n<p><strong>2.\u8f74\u7a81\u9ad3\u9798\u518d\u751f\u7b56\u7565\uff1a<\/strong>\u9488\u5bf9\u810a\u9ad3\u635f\u4f24\u540e\u6b8b\u7559\u8f74\u7a81\u7684\u529f\u80fd\u6062\u590d\uff0c\u7814\u7a76\u91cd\u70b9\u805a\u7126\u4e8e\u79fb\u690d\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u524d\u4f53\u7ec6\u80de\uff08OPC\uff09\u5b9e\u73b0\u9ad3\u9798\u518d\u751f\u3002\u80da\u80ce\u5e72\u7ec6\u80de\uff08ESC\uff09\u6216\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\u5206\u5316\u7684OPC\u88ab\u690d\u5165\u635f\u4f24\u533a\u5468\u8fb9\uff08\u800c\u975e\u635f\u4f24\u8154\uff09\uff0c\u53ef\u5305\u88f9\u5bbf\u4e3b\u8f74\u7a81\u5f62\u6210\u9ad3\u9798\uff0c\u51cf\u5c11\u7a7a\u6d1e\u5e76\u6539\u5584\u795e\u7ecf\u4f20\u5bfc\u3002<\/p>\n<p>\u4f8b\u5982\uff0cTsuji\u56e2\u961f\u5728\u5c0f\u9f20\u5b9e\u9a8c\u4e2d\u8bc1\u5b9eiPSC\u6765\u6e90\u7684NSC\u80fd\u4fc3\u8fdb\u9ad3\u9798\u518d\u751f\u548c\u8f74\u7a81\u751f\u957f\uff0c\u5e76\u5df2\u542f\u52a8\u5168\u7403\u9996\u4e2a\u76f8\u5173\u4e34\u5e8a\u8bd5\u9a8c\uff08jRCTa031190228\uff09\uff0c\u5728\u60a3\u8005\u4f24\u540e24\u5929\u5185\u79fb\u690d\u4ebaiPSC-NSC\u3002<\/p>\n<p><strong>3.\u529f\u80fd\u6027\u795e\u7ecf\u4e2d\u7ee7\u91cd\u5efa\uff1a<\/strong>NSC\u7684\u6838\u5fc3\u6f5c\u529b\u5728\u4e8e\u5206\u5316\u4e3a\u795e\u7ecf\u5143\u540e\u5f62\u6210\u8de8\u635f\u4f24\u533a\u7684\u201d\u795e\u7ecf\u4e2d\u7ee7\u201d\u3002\u79fb\u690d\u7684NSC\u53ef\u5206\u5316\u6210\u5174\u594b\u6027\u4e2d\u95f4\u795e\u7ecf\u5143\uff0c\u66ff\u4ee3\u4e22\u5931\u7684\u795e\u7ecf\u5143\u5e76\u5145\u5f53\u201d\u6865\u6881\u201d\uff0c\u91cd\u65b0\u8fde\u63a5\u65ad\u88c2\u7684\u4e0a\u4e0b\u884c\u795e\u7ecf\u901a\u8def\u3002<\/p>\n<p>\u540c\u65f6\uff0c\u5176\u5206\u5316\u7684\u80f6\u8d28\u7ec6\u80de\uff08\u5982\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\uff09\u53ef\u652f\u6301\u5bbf\u4e3b\u8f74\u7a81\u518d\u751f\u3002\u8fd9\u79cd\u7ed3\u5408\u795e\u7ecf\u5143\u66ff\u4ee3\u4e0e\u56de\u8def\u91cd\u5efa\u7684\u7b56\u7565\uff0c\u65e8\u5728\u6062\u590d\u8fd0\u52a8\u611f\u89c9\u4f20\u5bfc\u529f\u80fd\uff0c\u662f\u5f53\u524d\u7814\u7a76\u7684\u91cd\u70b9\u65b9\u5411\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\"><\/span>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u4e34\u5e8a\u8bd5\u9a8c<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>NSC\/NPC\u7684\u4e34\u5e8a\u8bd5\u9a8c\u59cb\u4e8e20\u4e16\u7eaa90\u5e74\u4ee3\u672b\uff0c\u5c06\u4eba\u7c7b\u80ce\u513f\u810a\u9ad3\u7ec4\u7ec7\u79fb\u690d\u5230\u60a3\u6709\u810a\u9ad3\u7a7a\u6d1e\u75c7\u7684SCI\u60a3\u8005\u4f53\u5185\uff0c\u4e3b\u8981\u76ee\u7684\u662f\u9632\u6b62\u56ca\u80bf\u8fdb\u4e00\u6b65\u6269\u5927\u3002\u8be5\u8bd5\u9a8c\u5e76\u672a\u5f97\u51fa\u7ed3\u8bba\uff0c\u4e5f\u672a\u62a5\u544a\u529f\u80fd\u6062\u590d\u60c5\u51b5\u3002\u6b64\u540e\uff0c\u4eba\u4eec\u4f7f\u7528\u4e0d\u540c\u6765\u6e90\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\u8fdb\u884c\u4e86\u591a\u9879I\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p>\u6240\u6709\u8fd9\u4e9b\u7814\u7a76\u7684\u4e3b\u8981\u76ee\u7684\u662f\u4f7f\u521d\u6b21\u635f\u4f24\u540e\u4fdd\u7559\u7684\u8f74\u7a81\u91cd\u65b0\u9ad3\u9798\u5316\uff0c\u5e76\u53ef\u80fd\u4fdd\u62a4\u5269\u4f59\u7684\u810a\u9ad3\u7ec4\u7ec7\u514d\u4e8e\u7ee7\u53d1\u6027\u9000\u5316\u3002\u8fd9\u4e9b\u8bd5\u9a8c\u7684\u57fa\u7840\u662f\u4e09\u5927\u7ec6\u80de\u6765\u6e90\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_%E8%83%9A%E8%83%8E%E5%B9%B2%E7%BB%86%E8%83%9E%E8%A1%8D%E7%94%9F%E7%9A%84%E5%B0%91%E7%AA%81%E8%83%B6%E8%B4%A8%E7%BB%86%E8%83%9E%E7%A5%96%E7%BB%86%E8%83%9E%EF%BC%88OPC%EF%BC%89%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\"><\/span><strong>1. \u80da\u80ce\u5e72\u7ec6\u80de\u884d\u751f\u7684\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u7956\u7ec6\u80de\uff08OPC\uff09\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>2011\u5e74\uff0c\u6e90\u81ea\u4eba\u7c7b\u80da\u80ce\u5e72\u7ec6\u80de\uff08ESC\uff09\u7684\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u7956\u7ec6\u80de\uff08OPC\uff09\u662f\u9996\u4e2a\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u4eba\u4f53\u8bd5\u9a8c\u7684ESC\u884d\u751f\u7ec6\u80de\u4ea7\u54c1\u3002<\/p>\n<p>2012\u5e74\uff0cGeron\u516c\u53f8\u8d5e\u52a9\u4e86\u4e00\u9879\u8bc4\u4f30\u4eba\u7c7b\u80da\u80ce\u5e72\u7ec6\u80de\u7597\u6cd5\u7684\u9996\u6b21\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\u3002\u8be5\u5b9e\u9a8c\u662f\u9488\u5bf95\u540d\u80f8\u690eSCI\u60a3\u8005\u7684\u521d\u59cbI\u671f\u7814\u7a76\uff0c\u5e76\u8bc1\u660e\u4e86\u5176\u5b89\u5168\u6027\u3002<\/p>\n<p>2022\u5e74\uff0c\u5728\u4e00\u9879\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u7956\u7ec6\u80de\u6cbb\u7597\u4e9a\u6025\u6027\u9888\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u76841\/2a\u671f\u5242\u91cf\u9012\u589e\u7814\u7a76\u4e2d\uff08NCT02302157\uff0c25\u540d\u9888\u690e\u635f\u4f24\u60a3\u8005\uff09\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201737-68d3e161d0eeb.jpg\" alt=\"\" title=\"\"><figcaption><\/figcaption><\/figure>\n<p><strong>\u7ed3\u679c\u6e05\u6670\u5730\u8bc1\u660e\u4e86\u5176\u5b89\u5168\u6027\uff0c\u540c\u65f6\u8868\u660e\u51e0\u4e4e\u6240\u6709\u60a3\u8005\u90fd\u80fd\u6062\u590d\u4e00\u4e2a\u8282\u6bb5\u7684\u795e\u7ecf\u529f\u80fd\uff0c\u4e09\u5206\u4e4b\u4e00\u7684\u60a3\u8005\u81f3\u5c11\u80fd\u6062\u590d\u4e00\u4fa7\u7684\u4e24\u4e2a\u8282\u6bb5\u7684\u795e\u7ecf\u529f\u80fd<\/strong>\u3002\u8be5\u7814\u7a76\u63d0\u4f9b\u4e86\u5b9d\u8d35\u7684\u4fe1\u606f\uff0c\u53ef\u7528\u4e8e\u8bc4\u4f30\u5e72\u7ec6\u80de\u6cbb\u7597\u4e9a\u6025\u6027SCI\u7684\u540e\u7eed\u6b65\u9aa4\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_%E8%83%8E%E5%84%BF%E8%84%91%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88HuCNS-SC%C2%AE%EF%BC%89%E7%9A%84%E7%A0%94%E7%A9%B6%E4%B8%8E%E7%BB%88%E6%AD%A2\"><\/span><strong>2. \u80ce\u513f\u8111\u795e\u7ecf\u5e72\u7ec6\u80de\uff08HuCNS-SC\u00ae\uff09\u7684\u7814\u7a76\u4e0e\u7ec8\u6b62<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Stem Cells Inc.\u516c\u53f8\u57fa\u4e8e\u80ce\u513f\u8111\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSCs\uff09\u5f00\u5c55\u4e86\u4e24\u9879\u4e34\u5e8a\u8bd5\u9a8c\uff1a\u9996\u9879\u9488\u5bf912\u4f8b\u80f8\u690e\u635f\u4f24\uff08NCT01321333\uff09\uff0c\u7b2c\u4e8c\u9879\u8ba1\u5212\u7eb3\u516531\u4f8b\u6162\u6027\u9888\u690e\u635f\u4f24\u60a3\u8005\uff08NCT02163876\uff09\u3002\u7814\u7a76\u663e\u793a\u79fb\u690d\u7ec6\u80de\u603b\u4f53\u5b89\u5168\uff0c\u4f46\u529f\u80fd\u6539\u5584\u6548\u679c\u672a\u8fbe\u5230\u9884\u8bbe\u9608\u503c\uff0c\u5bfc\u81f4\u9879\u76ee\u63d0\u524d\u7ec8\u6b62\uff0c\u516c\u53f8\u6700\u7ec8\u505c\u6b62\u4e86\u810a\u9ad3\u635f\u4f24\u7814\u7a76\u8ba1\u5212\u3002\u8fd9\u4e00\u7ed3\u679c\u51f8\u663e\u4e86\u80ce\u513f\u6e90\u5e72\u7ec6\u80de\u5728\u4fc3\u8fdb\u663e\u8457\u529f\u80fd\u6062\u590d\u65b9\u9762\u7684\u5c40\u9650\u6027\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_%E8%83%8E%E5%84%BF%E8%84%8A%E9%AB%93%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88NSI-566%EF%BC%89%E5%8F%8A%E5%85%B6%E4%BB%96%E8%BF%9B%E8%A1%8C%E4%B8%AD%E8%AF%95%E9%AA%8C\"><\/span><strong>3. \u80ce\u513f\u810a\u9ad3\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSI-566\uff09\u53ca\u5176\u4ed6\u8fdb\u884c\u4e2d\u8bd5\u9a8c<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>2018\u5e74\uff0c\u8fdb\u884c\u4e86\u4e00\u9879\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684\u9996\u6b21\u4eba\u4f53I\u671f\u7814\u7a76\uff0c\u6d4b\u8bd5\u4e86\u4eba\u810a\u9ad3\u6e90\u6027\u795e\u7ecf\u5e72\u7ec6\u80de (NSI-566) \u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24 (SCI) \u7684\u53ef\u884c\u6027\u548c\u5b89\u5168\u6027\u3002<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 1111px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201737-68d3e161ecf84.jpg\" alt=\"\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684\u9996\u6b21\u4eba\u4f53I\u671f\u7814\u7a76\" width=\"1101\" height=\"376\" title=\"\"><p class=\"wp-caption-text\">\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u810a\u9ad3\u635f\u4f24\u7684\u9996\u6b21\u4eba\u4f53I\u671f\u7814\u7a76<\/p><\/div><figcaption><\/figcaption><\/figure>\n<p>\u5728\u672c\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u56db\u540dT2-T12\u810a\u9ad3\u635f\u4f24 (SCI) \u60a3\u8005\u63a5\u53d7\u4e86\u6cbb\u7597\uff0c\u5305\u62ec\u79fb\u9664\u810a\u67f1\u5185\u56fa\u5b9a\u7269\u3001\u690e\u677f\u5207\u9664\u672f\u548c\u786c\u810a\u819c\u5207\u5f00\u672f\uff0c\u968f\u540e\u8fdb\u884c\u516d\u6b21\u4e2d\u7ebf\u53cc\u4fa7\u7acb\u4f53\u5b9a\u5411\u6ce8\u5c04 NSI-566 \u7ec6\u80de\u3002\u6240\u6709\u53d7\u8bd5\u8005\u5747\u5bf9\u624b\u672f\u8010\u53d7\u826f\u597d\uff0c<strong>\u8fc4\u4eca\u4e3a\u6b62\uff08\u79fb\u690d\u540e18-27\u4e2a\u6708\uff09\u672a\u51fa\u73b0\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002<\/strong><\/p>\n<p>\u5728\u4e24\u540d\u53d7\u8bd5\u8005\u4e2d\uff0c<strong>\u4f7f\u7528ISNCSCI\u8fd0\u52a8\u548c\u611f\u89c9\u8bc4\u5206\u68c0\u6d4b\u5230\u4e00\u81f3\u4e24\u4e2a\u7ea7\u522b\u7684\u795e\u7ecf\u529f\u80fd\u6539\u5584\u3002\u6211\u4eec\u7684\u7814\u7a76\u7ed3\u679c\u652f\u6301 NSI-566 \u79fb\u690d\u81f3\u810a\u9ad3\u635f\u4f24\u90e8\u4f4d\u7684\u5b89\u5168\u6027<\/strong>\uff0c\u5e76\u4e14\u5176\u4e2d\u4e09\u540d\u53d7\u8bd5\u8005\u7684\u65e9\u671f\u6f5c\u5728\u7597\u6548\u8ff9\u8c61\u503c\u5f97\u5728\u5242\u91cf\u9012\u589e\u7814\u7a76\u4e2d\u8fdb\u4e00\u6b65\u63a2\u7d22NSI-566\u7ec6\u80de\u3002<\/p>\n<ul class=\"wp-block-list\">\n<li>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u957f\u671f\u4e34\u5e8a\u7597\u6548\u5982\u4f55\uff1f\u5b89\u5168\u6027\u600e\u4e48\u6837\uff1f<\/li>\n<\/ul>\n<p>2025\u5e741\u6708\uff0c\u6765\u81ea\u52a0\u5229\u798f\u5c3c\u4e9a\u5927\u5b66\u7b49\u7814\u7a76\u673a\u6784\u7684\u79d1\u5b66\u5bb6\u4eec\uff0c\u7ecf\u8fc7\u4e94\u5e74\u7684\u4e34\u5e8a\u8ddf\u8e2a\u7814\u7a76\uff0c\u5728\u300aCell Reports Medicine\u300b\u671f\u520a\u4e0a\u53d1\u5e03\u4e86\u9898\u4e3a\u300aLong-term clinical and safety outcomes from a single-site phase 1 study of neural stem cell transplantation for chronic thoracic spinal cord injury\u300b\u7684\u7814\u7a76\u62a5\u544a\uff0c\u7814\u7a76\u8005\u53d6\u5f97\u4e86\u4e00\u4e9b\u4ee4\u4eba\u9f13\u821e\u7684\u6210\u679c\uff1a<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 619px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201738-68d3e16216784.jpg\" alt=\"\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u80f8\u690e\u810a\u9ad3\u635f\u4f24\u7684\u5355\u4e2d\u5fc3 I \u671f\u4e34\u5e8a\u7814\u7a76\u7684\u957f\u671f\u4e34\u5e8a\u548c\u5b89\u5168\u6027\u7ed3\u679c\" width=\"609\" height=\"453\" title=\"\"><p class=\"wp-caption-text\">\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u6162\u6027\u80f8\u690e\u810a\u9ad3\u635f\u4f24\u7684\u5355\u4e2d\u5fc3 I \u671f\u4e34\u5e8a\u7814\u7a76\u7684\u957f\u671f\u4e34\u5e8a\u548c\u5b89\u5168\u6027\u7ed3\u679c<\/p><\/div><figcaption><\/figcaption><\/figure>\n<p><strong>\u79fb\u690d\u5b89\u5168\u6027\u5f97\u5230\u9a8c\u8bc1\uff1a<\/strong>\u56db\u540d\u60a3\u8005\u5728\u624b\u672f\u540e\u5747\u8010\u53d7\u826f\u597d\uff0c\u6ca1\u6709\u51fa\u73b0\u4e25\u91cd\u7684\u4e0d\u826f\u53cd\u5e94\uff08SAEs\uff09\u3002\u5c3d\u7ba1\u5176\u4e2d\u4e00\u540d\u60a3\u8005\u56e0\u672f\u540e\u5e76\u53d1\u611f\u67d3\u53bb\u4e16\uff0c\u4f46\u6574\u4f53\u6765\u770b\uff0c\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u5728\u77ed\u671f\u548c\u957f\u671f\u5185\u90fd\u8868\u73b0\u51fa\u8f83\u9ad8\u7684\u5b89\u5168\u6027\u3002<\/p>\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201738-68d3e16222fc0.jpg\" width=\"512\" height=\"512\" alt=\"\" title=\"\"><\/figure>\n<p><strong>\u795e\u7ecf\u8fd0\u52a8\u529f\u80fd\u548c\u611f\u89c9\u529f\u80fd\u5f97\u5230\u6539\u5584\uff1a<\/strong>\u7814\u7a76\u62a5\u544a\u663e\u793a\uff0c4\u4f8b\u53d7\u8bd5\u8005\u5747\u80fd\u826f\u597d\u5730\u8010\u53d7\u5e72\u7ec6\u80de\u79fb\u690d\u624b\u672f\uff0c\u5176\u4e2d2\u4f8b\u53d7\u8bd5\u8005\u5728\u79fb\u690d\u540e5\u5e74\u5185\uff0c\u83b7\u5f97\u4e86\u6301\u4e45\u7684\u808c\u7535\u56fe\u91cf\u5316\u795e\u7ecf\u529f\u80fd\u6539\u5584\u8bc1\u636e\uff0c\u4e14\u795e\u7ecf\u8fd0\u52a8\u548c\u611f\u89c9\u8bc4\u5206\u6709\u6240\u63d0\u9ad8\u3002\u53e6\u5916\u4e24\u9879\u5c1a\u672a\u516c\u5e03\u7ed3\u679c\uff0c\u97e9\u56fd\u4e00\u9879\u7814\u7a76\u4f7f\u7528ESC\u884d\u751f\u7684PSA-NCAM\u9633\u6027\u795e\u7ecf\u524d\u4f53\u7ec6\u80de\uff08NCT04812431\uff09\uff0c\u4ee5\u53ca\u65e5\u672c\u4e00\u9879\u7814\u7a76\u5c06iPSC\u884d\u751f\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u81f3\u4e9a\u6025\u6027\u60a3\u8005\uff0c\u76ee\u524d\u5c1a\u672a\u516c\u5e03\u7ed3\u679c\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"4_%E5%85%B1%E5%90%8C%E6%8C%91%E6%88%98%E4%B8%8E%E6%9C%AA%E6%9D%A5%E6%96%B9%E5%90%91\"><\/span><strong>4. \u5171\u540c\u6311\u6218\u4e0e\u672a\u6765\u65b9\u5411<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u4e0a\u8ff0\u8bd5\u9a8c\u5747\u91c7\u7528\u5728\u635f\u4f24\u533a\u5468\u8fb9\uff08\u6216\u90e8\u5206\u4fb5\u5165\u635f\u4f24\u8154\uff09\u6ce8\u5c04\u7ec6\u80de\u7684\u7b56\u7565\uff0c\u4e14\u5747\u672a\u8054\u5408\u751f\u957f\u56e0\u5b50\u652f\u6301\u79fb\u690d\u7ec6\u80de\u5b58\u6d3b\u3002\u7814\u7a76\u8868\u660e\uff0c\u7f3a\u4e4f\u751f\u957f\u56e0\u5b50\u53ef\u80fd\u5bfc\u81f4\u79fb\u690d\u7269\u5728\u635f\u4f24\u6838\u5fc3\u96be\u4ee5\u957f\u671f\u5b58\u6d3b\u3002\u5c3d\u7ba1\u6240\u6709\u8bd5\u9a8c\u56e0\u6837\u672c\u91cf\u5c0f\u65e0\u6cd5\u9a8c\u8bc1\u7597\u6548\uff0c\u4f46\u4e00\u81f4\u8bc1\u5b9e\u4e86\u5e72\u7ec6\u80de\/\u7956\u7ec6\u80de\u79fb\u690d\u7684\u57fa\u672c\u5b89\u5168\u6027\u3002\u672a\u6765\u9700\u4f18\u5316\u7ec6\u80de\u9012\u9001\u7b56\u7565\u3001\u7ed3\u5408\u795e\u7ecf\u8425\u517b\u56e0\u5b50\u6216\u751f\u7269\u6750\u6599\uff0c\u5e76\u5728\u66f4\u5927\u89c4\u6a21\u8bd5\u9a8c\u4e2d\u9a8c\u8bc1\u529f\u80fd\u6062\u590d\u6548\u679c\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%84%8A%E9%AB%93%E6%8D%9F%E4%BC%A4%E7%9A%84%E6%9C%AA%E6%9D%A5%E5%B1%95%E6%9C%9B\"><\/span>\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u7684\u672a\u6765\u5c55\u671b<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u79fb\u690d\u795e\u7ecf\u5e72\u7ec6\u80de (NSC) \u7684\u8f74\u7a81\u751f\u957f\u53ca\u5176\u4e0e\u5bbf\u4e3b\u795e\u7ecf\u5143\u7684\u91cd\u65b0\u8fde\u63a5\u4e3a\u810a\u9ad3\u635f\u4f24 (SCI) \u7684\u6cbb\u7597\u5e26\u6765\u4e86\u5e0c\u671b\u3002\u6211\u4eec\u7684\u65b9\u6cd5\u65e8\u5728\u5728\u635f\u4f24\u90e8\u4f4d\u5f62\u6210\u4fee\u590d\u6027\u795e\u7ecf\u4e2d\u7ee7\u3002\u6211\u4eec\u76f8\u4fe1\uff0c\u6211\u4eec\u7684\u65b9\u6cd5\u5df2\u7ecf\u6210\u719f\uff0c\u503c\u5f97\u8fdb\u884c\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p><strong>\u6838\u5fc3\u7b56\u7565\u4e0e\u4e34\u5e8a\u8f6c\u5316\u6f5c\u529b\uff1a<\/strong>\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSC\uff09\u79fb\u690d\u7684\u6838\u5fc3\u76ee\u6807\u662f\u901a\u8fc7\u5728\u635f\u4f24\u90e8\u4f4d\u6784\u5efa\u529f\u80fd\u6027\u795e\u7ecf\u4e2d\u7ee7\uff0c\u4fc3\u8fdb\u65b0\u751f\u8f74\u7a81\u751f\u957f\u5e76\u4e0e\u5bbf\u4e3b\u795e\u7ecf\u5143\u91cd\u65b0\u8fde\u63a5\u3002\u8fd9\u4e00\u7b56\u7565\u5df2\u4ece\u4e34\u5e8a\u524d\u7814\u7a76\u53d1\u5c55\u5230\u6210\u719f\u9636\u6bb5\uff0c\u5177\u5907\u5f00\u5c55\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6761\u4ef6\u3002<\/p>\n<p>\u672a\u6765\u5de5\u4f5c\u5c06\u805a\u7126\u4e8e\u4f18\u5316\u79fb\u690d\u65b9\u6848\uff0c\u4f8b\u5982\u5c06NSC\u4e0e\u751f\u7269\u5de5\u7a0b\u652f\u67b6\u7ed3\u5408\uff0c\u4ee5\u5f15\u5bfc\u8f74\u7a81\u5b9a\u5411\u5ef6\u4f38\u5e76\u5f62\u6210\u66f4\u7cbe\u786e\u7684\u795e\u7ecf\u56de\u8def\u8fde\u63a5\uff1b\u540c\u65f6\uff0c\u901a\u8fc7\u9012\u9001\u795e\u7ecf\u8425\u517b\u56e0\u5b50\u6216\u8f74\u7a81\u5bfc\u5411\u5206\u5b50\uff08\u5982Netrin\u3001Slit\u7b49\uff09\uff0c\u53ef\u7279\u5f02\u6027\u5f15\u5bfc\u79fb\u690d\u7269\u8f74\u7a81\u9776\u5411\u5bbf\u4e3b\u7684\u8fd0\u52a8\u63a7\u5236\u533a\u57df\uff0c\u63d0\u5347\u795e\u7ecf\u4e2d\u7ee7\u7684\u7cbe\u51c6\u6027\u548c\u529f\u80fd\u6548\u7387\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%A2%9E%E6%95%88%E6%8A%80%E6%9C%AF%E4%B8%8E%E5%8D%8F%E5%90%8C%E6%8C%91%E6%88%98%EF%BC%9A%E8%BF%9B%E4%B8%80%E6%AD%A5%E5%A2%9E%E6%95%88%E7%AD%96%E7%95%A5%E5%8C%85%E6%8B%AC%EF%BC%9A\"><\/span><strong>\u589e\u6548\u6280\u672f\u4e0e\u534f\u540c\u6311\u6218\uff1a<\/strong>\u8fdb\u4e00\u6b65\u589e\u6548\u7b56\u7565\u5305\u62ec\uff1a<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u2460\u5728\u79fb\u690d\u7269\u4e2d\u5bcc\u96c6\u5174\u594b\u6027\u795e\u7ecf\u5143\uff08\u5982\u810a\u9ad3V2a\u4e2d\u95f4\u795e\u7ecf\u5143\uff09\uff0c\u589e\u5f3a\u4e0b\u884c\u8fd0\u52a8\u4fe1\u53f7\u4f20\u5bfc\u80fd\u529b\uff1b<\/p>\n<p>\u2461\u901a\u8fc7\u6291\u5236\u5bbf\u4e3bPTEN\u57fa\u56e0\u7b49\u9014\u5f84\uff0c\u6fc0\u6d3b\u6210\u5e74\u8f74\u7a81\u7684\u518d\u751f\u6f5c\u80fd\uff0c\u4fc3\u8fdb\u5176\u4e0e\u79fb\u690d\u795e\u7ecf\u5143\u7684\u6574\u5408\uff1b<\/p>\n<p>\u2462\u7ed3\u5408\u5b9a\u5236\u5316\u5eb7\u590d\u8bad\u7ec3\u4e0e\u786c\u819c\u5916\u7535\u523a\u6fc0\uff0c\u5f3a\u5316\u65b0\u56de\u8def\u7684\u53ef\u5851\u6027\u548c\u529f\u80fd\u9002\u5e94\u6027\u3002<\/p>\n<p>\u7136\u800c\uff0c\u9700\u8b66\u60d5\u8f74\u7a81\u201d\u8fc7\u5ea6\u751f\u957f\u201d\u53ef\u80fd\u5bfc\u81f4\u5f02\u5e38\u795e\u7ecf\u8fde\u63a5\u7684\u98ce\u9669\u3002\u5f53\u524d\u9886\u57df\u5df2\u7a81\u7834\u201d\u80fd\u5426\u518d\u751f\u201d\u7684\u74f6\u9888\uff0c\u6b63\u8fc8\u5411\u201d\u5982\u4f55\u7cbe\u51c6\u5f15\u5bfc\u518d\u751f\u201d\u7684\u65b0\u9636\u6bb5\u2014\u2014\u4f18\u5316\u795e\u7ecf\u751f\u957f\u7684\u65b9\u5411\u6027\u3001\u5b89\u5168\u6027\u4e0e\u529f\u80fd\u6574\u5408\uff0c\u662f\u672a\u6765\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6838\u5fc3\u6311\u6218\u3002<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u53c2\u8003\u8d44\u6599\uff1a[1]:Lu, P., Sinopoulou, E., Rosenzweig, E.S., Blesch, A., Tuszynski, M.H. (2025). Neural Stem Cells for Spinal Cord Injury. In: Tuszynski, M.H. (eds) Translational Neuroscience. Springer, Cham. https:\/\/doi.org\/10.1007\/978-3-031-89307-0_14<\/p>\n<p>\u514d\u8d23\u8bf4\u660e\uff1a\u672c\u6587\u4ec5\u7528\u4e8e\u4f20\u64ad\u79d1\u666e\u77e5\u8bc6\uff0c\u5206\u4eab\u884c\u4e1a\u89c2\u70b9\uff0c\u4e0d\u6784\u6210\u4efb\u4f55\u4e34\u5e8a\u8bca\u65ad\u5efa\u8bae\uff01\u676d\u5409\u5e72\u7ec6\u80de\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4e0d\u80fd\u66ff\u4ee3\u533b\u751f\u6216\u836f\u5242\u5e08\u7684\u4e13\u4e1a\u5efa\u8bae\u3002\u5982\u6709\u7248\u6743\u7b49\u7591\u95ee\uff0c\u8bf7\u968f\u65f6\u8054\u7cfb\u6211<\/p><\/blockquote>","protected":false},"excerpt":{"rendered":"<p>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u810a\u9ad3\u635f\u4f24\u6b63\u6210\u4e3a\u518d\u751f\u533b\u5b66\u7684\u91cd\u8981\u7a81\u7834\u30022025\u6700\u65b0\u7814\u7a76\u663e\u793a\uff0c\u795e\u7ecf\u5e72\u7ec6\u80de\u53ef\u901a\u8fc7\u8f74\u7a81\u518d\u751f\u3001\u9ad3\u9798\u4fee\u590d\u53ca\u795e\u7ecf\u4e2d\u7ee7\u91cd\u5efa\uff0c\u4fc3\u8fdb\u810a\u9ad3\u635f\u4f24\u540e\u7684\u8fd0\u52a8\u4e0e\u611f\u89c9\u529f\u80fd\u6062\u590d\u3002\u672c\u6587\u7cfb\u7edf\u89e3\u6790\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u7684\u4fee\u590d\u673a\u5236\u3001\u4e3b\u8981\u4e34\u5e8a\u8bd5\u9a8c\u53ca\u672a\u6765\u53d1\u5c55\u65b9\u5411\uff0c\u4e3a\u5173\u6ce8\u810a\u9ad3\u635f\u4f24\u6cbb\u7597\u548c\u795e\u7ecf\u518d\u751f\u524d\u6cbf\u7684\u8bfb\u8005\u63d0\u4f9b\u6743\u5a01\u53c2\u8003\u3002<\/p>","protected":false},"author":1,"featured_media":19237,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":{"footnotes":""},"categories":[73],"tags":[173,164,174],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts\/19245"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/comments?post=19245"}],"version-history":[{"count":2,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts\/19245\/revisions"}],"predecessor-version":[{"id":19355,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts\/19245\/revisions\/19355"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/media\/19237"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/media?parent=19245"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/categories?post=19245"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/tags?post=19245"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}