{"id":20701,"date":"2025-12-01T15:19:09","date_gmt":"2025-12-01T07:19:09","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=20701"},"modified":"2025-12-01T15:19:32","modified_gmt":"2025-12-01T07:19:32","slug":"https-www-hjtdsm-cn-stem-cells-stem-cell-therapy-20701-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20701.html","title":{"rendered":"\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\uff1a\u57fa\u4e8e25\u9879\u7814\u7a76\u7684\u73b0\u72b6\u3001\u673a\u5236\u4e0e\u672a\u6765\u7684\u6311\u6218\u53ca\u673a\u9047"},"content":{"rendered":"<p>\u8fd1\u5e74\u6765\uff0c\u7ec8\u672b\u671f\u809d\u75c5\u5df2\u6210\u4e3a\u5168\u7403\u8303\u56f4\u5185\u9ad8\u53d1\u75c5\u7387\u4e0e\u9ad8\u6b7b\u4ea1\u7387\u7684\u4e3b\u8981\u75be\u75c5\u4e4b\u4e00\uff0c\u5176\u75c5\u56e0\u591a\u6837\uff0c\u5305\u62ec\u9152\u7cbe\u6027\u809d\u75c5\u3001\u75c5\u6bd2\u6027\u809d\u708e\u3001\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u75c5\u548c\u4ee3\u8c22\u76f8\u5173\u6027\u809d\u75c5\u3002\u76ee\u524d\uff0c\u809d\u79fb\u690d\u4ecd\u662f\u552f\u4e00\u80fd\u663e\u8457\u6539\u5584\u9884\u540e\u7684\u6cbb\u7597\u65b9\u6cd5\uff0c\u4f46\u4f9b\u4f53\u77ed\u7f3a\u3001\u514d\u75ab\u6392\u65a5\u53ca\u9ad8\u6602\u8d39\u7528\u4e25\u91cd\u9650\u5236\u5176\u5e94\u7528\u3002\u8fd9\u4e00\u6cbb\u7597\u7a7a\u767d\u4fc3\u4f7f\u79d1\u5b66\u754c\u79ef\u6781\u63a2\u7d22\u66ff\u4ee3\u7597\u6cd5\uff0c\u5176\u4e2d\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\u4e2d\u5c55\u73b0\u51fa\u7a81\u7834\u6027\u6f5c\u529b\u3002<\/p>\n<section 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href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20701.html\/#%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%BB%88%E6%9C%AB%E6%9C%9F%E8%82%9D%E7%97%85%EF%BC%9A%E5%9F%BA%E4%BA%8E25%E9%A1%B9%E7%A0%94%E7%A9%B6%E7%9A%84%E7%8E%B0%E7%8A%B6%E3%80%81%E6%9C%BA%E5%88%B6%E4%B8%8E%E6%9C%AA%E6%9D%A5%E7%9A%84%E6%8C%91%E6%88%98%E5%8F%8A%E6%9C%BA%E9%81%87\" >\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\uff1a\u57fa\u4e8e25\u9879\u7814\u7a76\u7684\u73b0\u72b6\u3001\u673a\u5236\u4e0e\u672a\u6765\u7684\u6311\u6218\u53ca\u673a\u9047<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20701.html\/#%E7%9B%AE%E5%89%8D%E6%B2%BB%E7%96%97%E8%82%9D%E8%84%8F%E7%96%BE%E7%97%85%E7%9A%84%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%8D%E7%B1%BB%E6%9C%89%E5%93%AA%E4%BA%9B%EF%BC%9F\" >\u76ee\u524d\u6cbb\u7597\u809d\u810f\u75be\u75c5\u7684\u5e72\u7ec6\u80de\u79cd\u7c7b\u6709\u54ea\u4e9b\uff1f<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20701.html\/#1_%E8%82%9D%E8%84%8F%E6%9D%A5%E6%BA%90%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9A%E5%86%85%E6%BA%90%E6%80%A7%E5%86%8D%E7%94%9F%E6%BD%9C%E5%8A%9B%E4%B8%8E%E4%B8%B4%E5%BA%8A%E7%93%B6%E9%A2%88\" >1. \u809d\u810f\u6765\u6e90\u5e72\u7ec6\u80de\uff1a\u5185\u6e90\u6027\u518d\u751f\u6f5c\u529b\u4e0e\u4e34\u5e8a\u74f6\u9888<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20701.html\/#2_%E8%83%9A%E8%83%8E%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9A%E5%A4%9A%E8%83%BD%E6%80%A7%E6%BD%9C%E5%8A%9B%E4%B8%8E%E5%AE%89%E5%85%A8%E4%BC%A6%E7%90%86%E5%9B%B0%E5%A2%83\" >2. \u80da\u80ce\u5e72\u7ec6\u80de\uff1a\u591a\u80fd\u6027\u6f5c\u529b\u4e0e\u5b89\u5168\u4f26\u7406\u56f0\u5883<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20701.html\/#3_%E8%AF%B1%E5%AF%BC%E5%A4%9A%E8%83%BD%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9A%E6%82%A3%E8%80%85%E7%89%B9%E5%BC%82%E6%80%A7%E4%BC%98%E5%8A%BF%E4%B8%8E%E8%87%B4%E7%98%A4%E9%A3%8E%E9%99%A9%E6%8C%91%E6%88%98\" >3. \u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff1a\u60a3\u8005\u7279\u5f02\u6027\u4f18\u52bf\u4e0e\u81f4\u7624\u98ce\u9669\u6311\u6218<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20701.html\/#4_%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9A%E5%A4%9A%E6%BA%90%E8%8E%B7%E5%8F%96%E4%B8%8E%E5%85%8D%E7%96%AB%E8%B0%83%E8%8A%82%E7%9A%84%E6%B2%BB%E7%96%97%E5%89%8D%E6%99%AF\" >4. \u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff1a\u591a\u6e90\u83b7\u53d6\u4e0e\u514d\u75ab\u8c03\u8282\u7684\u6cbb\u7597\u524d\u666f<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20701.html\/#%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%BB%88%E6%9C%AB%E6%9C%9F%E8%82%9D%E7%97%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%E5%92%8C%E5%8A%A8%E7%89%A9%E7%A0%94%E7%A9%B6\" >\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\u548c\u52a8\u7269\u7814\u7a76<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20701.html\/#%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%BB%88%E6%9C%AB%E6%9C%9F%E8%82%9D%E7%97%85%E7%9A%84%E6%A0%B8%E5%BF%83%E6%9C%BA%E5%88%B6\" >\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\u7684\u6838\u5fc3\u673a\u5236<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20701.html\/#%E6%8F%90%E9%AB%98%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%82%9D%E7%97%85%E7%96%97%E6%95%88%E7%9A%84%E6%96%B9%E6%B3%95%E6%9C%89%E5%93%AA%E4%BA%9B%EF%BC%9F\" >\u63d0\u9ad8\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u809d\u75c5\u7597\u6548\u7684\u65b9\u6cd5\u6709\u54ea\u4e9b\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a 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id=\"%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%BB%88%E6%9C%AB%E6%9C%9F%E8%82%9D%E7%97%85%EF%BC%9A%E5%9F%BA%E4%BA%8E25%E9%A1%B9%E7%A0%94%E7%A9%B6%E7%9A%84%E7%8E%B0%E7%8A%B6%E3%80%81%E6%9C%BA%E5%88%B6%E4%B8%8E%E6%9C%AA%E6%9D%A5%E7%9A%84%E6%8C%91%E6%88%98%E5%8F%8A%E6%9C%BA%E9%81%87\"><\/span>\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\uff1a\u57fa\u4e8e25\u9879\u7814\u7a76\u7684\u73b0\u72b6\u3001\u673a\u5236\u4e0e\u672a\u6765\u7684\u6311\u6218\u53ca\u673a\u9047<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>2025\u5e7411\u670828\u65e5\uff0c\u56fd\u9645\u671f\u520a\u300aStem Cell Research&amp;Therapy\u300b\u53d1\u8868\u9898\u4e3a<a href=\"https:\/\/link.springer.com\/article\/10.1186\/s13287-025-04788-3\" target=\"_blank\" rel=\"noopener nofollow\">\u300a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\uff1a\u6311\u6218\u4e0e\u673a\u9047\u300b<\/a>\u7684\u7efc\u8ff0\u6587\u7ae0\u3002\u7cfb\u7edf\u6c47\u603b25\u9879\u76f8\u5173\u4e34\u5e8a\u524d\u4e0e\u4e34\u5e8a\u7814\u7a76\uff0c\u6df1\u5165\u9610\u660e\u5176\u4f5c\u7528\u673a\u5236\uff0c\u5e76\u5256\u6790\u5f53\u524d\u9762\u4e34\u7684\u6311\u6218\u4e0e\u672a\u6765\u53d1\u5c55\u65b9\u5411[1]\u3002<\/p>\n<section><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-20707 aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_113747_587.png\" alt=\"\" width=\"654\" height=\"355\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_113747_587.png 654w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_113747_587-300x163.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_113747_587-18x10.png 18w\" sizes=\"(max-width: 654px) 100vw, 654px\" \/><\/section>\n<h2><span class=\"ez-toc-section\" id=\"%E7%9B%AE%E5%89%8D%E6%B2%BB%E7%96%97%E8%82%9D%E8%84%8F%E7%96%BE%E7%97%85%E7%9A%84%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%8D%E7%B1%BB%E6%9C%89%E5%93%AA%E4%BA%9B%EF%BC%9F\"><\/span><strong>\u76ee\u524d\u6cbb\u7597\u809d\u810f\u75be\u75c5\u7684\u5e72\u7ec6\u80de\u79cd\u7c7b\u6709\u54ea\u4e9b\uff1f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u76ee\u524d\u7528\u4e8e\u809d\u810f\u75be\u75c5\u6cbb\u7597\u7684\u5e72\u7ec6\u80de\u4e3b\u8981\u5305\u62ec\u809d\u810f\u6765\u6e90\u5e72\u7ec6\u80de\u3001<a href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/psc\/19896.html\/\" target=\"_blank\" rel=\"noopener\">\u80da\u80ce\u5e72\u7ec6\u80de<\/a>\u3001\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u548c<a href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/mscs\/20576.html\/\" target=\"_blank\" rel=\"noopener\">\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0648\u0633\u064a\u0637\u0629 \u0627\u0644\u0648\u0633\u064a\u0637\u0629 MSC (\u0641\u064a \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u062e\u0644\u064a\u0629)<\/a>\u3002\u88681\u603b\u7ed3\u4e86\u4e94\u7c7b\u5e72\u7ec6\u80de\u7684\u4e3b\u8981\u4f18\u52bf\u4e0e\u5c40\u9650\u6027\uff0c\u56fe1\u5219\u76f4\u89c2\u6bd4\u8f83\u4e86\u5b83\u4eec\u7684\u6765\u6e90\u3002<\/p>\n<section>\n<div id=\"attachment_20706\" style=\"width: 1388px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20706\" class=\"wp-image-20706 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_113945_276.png\" alt=\"\" width=\"1378\" height=\"223\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_113945_276.png 1378w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_113945_276-300x49.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_113945_276-1024x166.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_113945_276-768x124.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_113945_276-18x3.png 18w\" sizes=\"(max-width: 1378px) 100vw, 1378px\" \/><p id=\"caption-attachment-20706\" class=\"wp-caption-text\">\u56fe1\uff1a\u4e0d\u540c\u7684\u5e72\u7ec6\u80de\u6765\u6e90<\/p><\/div>\n<p>&nbsp;<\/p>\n<\/section>\n<section>\n<div id=\"attachment_20705\" style=\"width: 1499px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20705\" class=\"wp-image-20705 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_114007_883.png\" alt=\"\" width=\"1489\" height=\"835\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_114007_883.png 1489w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_114007_883-300x168.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_114007_883-1024x574.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_114007_883-768x431.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_114007_883-18x10.png 18w\" sizes=\"(max-width: 1489px) 100vw, 1489px\" \/><p id=\"caption-attachment-20705\" class=\"wp-caption-text\">\u88681\uff1a\u5404\u7c7b\u5e72\u7ec6\u80de\u7684\u4f18\u52bf\u548c\u5c40\u9650\u6027<\/p><\/div>\n<\/section>\n<h3><span class=\"ez-toc-section\" id=\"1_%E8%82%9D%E8%84%8F%E6%9D%A5%E6%BA%90%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9A%E5%86%85%E6%BA%90%E6%80%A7%E5%86%8D%E7%94%9F%E6%BD%9C%E5%8A%9B%E4%B8%8E%E4%B8%B4%E5%BA%8A%E7%93%B6%E9%A2%88\"><\/span><strong>1. \u809d\u810f\u6765\u6e90\u5e72\u7ec6\u80de\uff1a\u5185\u6e90\u6027\u518d\u751f\u6f5c\u529b\u4e0e\u4e34\u5e8a\u74f6\u9888<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u80c6\u9053\u5e72\u7ec6\u80de\u548c\u809d\u810f\u5e72\u7ec6\u80de\u5177\u6709\u663e\u8457\u7684\u518d\u751f\u6f5c\u529b\uff0c\u80fd\u5206\u5316\u4e3a\u809d\u7ec6\u80de\u3001\u80c6\u7ba1\u7ec6\u80de\u7b49\u3002\u4e34\u5e8a\u7814\u7a76\u5df2\u8bc1\u5b9e\u80ce\u6e90\u6027\u9020\u8840\u5e72\u7ec6\u80de\u53ef\u6539\u5584\u809d\u529f\u80fd\uff0c\u4f46\u80c6\u9053\u5e72\u7ec6\u80de\u79fb\u690d\u6548\u7387\u4f4e\u4e8e20%\uff0c\u4e14\u4fb5\u5165\u6027\u65b9\u6cd5\u96be\u4ee5\u4e34\u5e8a\u8f6c\u5316\uff0c\u4e9f\u9700\u7a81\u7834\u6269\u589e\u4e0e\u529f\u80fd\u6210\u719f\u7684\u6280\u672f\u74f6\u9888\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"2_%E8%83%9A%E8%83%8E%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9A%E5%A4%9A%E8%83%BD%E6%80%A7%E6%BD%9C%E5%8A%9B%E4%B8%8E%E5%AE%89%E5%85%A8%E4%BC%A6%E7%90%86%E5%9B%B0%E5%A2%83\"><\/span>2. \u80da\u80ce\u5e72\u7ec6\u80de\uff1a\u591a\u80fd\u6027\u6f5c\u529b\u4e0e\u5b89\u5168\u4f26\u7406\u56f0\u5883<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u80da\u80ce\u5e72\u7ec6\u80de\u5177\u6709\u65e0\u9650\u589e\u6b96\u4e0e\u591a\u5411\u5206\u5316\u80fd\u529b\uff0c\u80fd\u5206\u5316\u4e3a\u809d\u7ec6\u80de\u6837\u7ec6\u80de\u3002\u7136\u800c\uff0c\u5176\u4e34\u5e8a\u5e94\u7528\u9762\u4e34\u81f4\u7624\u98ce\u9669\u3001\u57fa\u56e0\u7ec4\u4e0d\u7a33\u5b9a\u6027\u53ca\u79fb\u690d\u540e\u514d\u75ab\u6392\u65a5\u95ee\u9898\u3002\u6b64\u5916\uff0c\u4f7f\u7528\u4eba\u7c7b\u80da\u80ce\u6240\u5f15\u53d1\u7684\u4f26\u7406\u4e89\u8bae\u4e5f\u4e25\u683c\u9650\u5236\u4e86\u5176\u53d1\u5c55\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"3_%E8%AF%B1%E5%AF%BC%E5%A4%9A%E8%83%BD%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9A%E6%82%A3%E8%80%85%E7%89%B9%E5%BC%82%E6%80%A7%E4%BC%98%E5%8A%BF%E4%B8%8E%E8%87%B4%E7%98%A4%E9%A3%8E%E9%99%A9%E6%8C%91%E6%88%98\"><\/span>3. \u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff1a\u60a3\u8005\u7279\u5f02\u6027\u4f18\u52bf\u4e0e\u81f4\u7624\u98ce\u9669\u6311\u6218<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSCs\uff09\u901a\u8fc7\u91cd\u7f16\u7a0b\u4f53\u7ec6\u80de\uff08\u5982\u6210\u7ea4\u7ef4\u7ec6\u80de\uff09\u751f\u6210\uff0c\u907f\u514d\u4e86\u4f7f\u7528\u80da\u80ce\u7684\u4f26\u7406\u95ee\u9898\u548c\u514d\u75ab\u6392\u65a5\uff0c\u56e0\u4e3a\u53ef\u751f\u4ea7\u60a3\u8005\u7279\u5f02\u6027\u7ec6\u80de\u3002iPSCs\u80fd\u5206\u5316\u4e3a\u529f\u80fd\u6027\u7684\u809d\u7ec6\u80de\u6837\u7ec6\u80de\uff0c\u5e76\u5728\u4f53\u5185\u6574\u5408\u5230\u809d\u5b9e\u8d28\u4e2d\u3002<\/p>\n<p>\u4f46\u4e34\u5e8a\u5e94\u7528\u6311\u6218\u5305\u62ec<span class=\"\">\u7578\u80ce\u7624<\/span>\u5f62\u6210\u98ce\u9669\u3001\u91cd\u7f16\u7a0b\u5f02\u5e38\u5bfc\u81f4\u5206\u5316\u80fd\u529b\u53d7\u635f\uff0c\u4ee5\u53ca\u4f7f\u7528\u75c5\u6bd2\u8f7d\u4f53\u53ef\u80fd\u5f15\u8d77\u57fa\u56e0\u7ec4\u6574\u5408\u548c\u8f6c\u57fa\u56e0\u91cd\u65b0\u6fc0\u6d3b\u3002\u5c3d\u7ba1\u5b89\u5168\u6027\u95ee\u9898\u672a\u5b8c\u5168\u89e3\u51b3\uff0ciPSCs\u5df2\u5728\u809d\u75c5\u6a21\u578b\u6784\u5efa\u548c\u836f\u7269\u7b5b\u9009\u4e2d\u53d6\u5f97\u8fdb\u5c55\uff0c\u5c24\u5176\u5728\u9884\u6d4b\u809d\u6bd2\u6027\u65b9\u9762\u6709\u4ef7\u503c\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"4_%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9A%E5%A4%9A%E6%BA%90%E8%8E%B7%E5%8F%96%E4%B8%8E%E5%85%8D%E7%96%AB%E8%B0%83%E8%8A%82%E7%9A%84%E6%B2%BB%E7%96%97%E5%89%8D%E6%99%AF\"><\/span>4. \u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff1a\u591a\u6e90\u83b7\u53d6\u4e0e\u514d\u75ab\u8c03\u8282\u7684\u6cbb\u7597\u524d\u666f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u6765\u81ea\u591a\u79cd\u7ec4\u7ec7\u5982\u9aa8\u9ad3\u3001\u8102\u80aa\u548c\u8110\u5e26\uff0c\u5177\u6709\u514d\u75ab\u8c41\u514d\u7279\u6027\uff08\u4f4e\u8868\u8fbe<span class=\"\">MHC<\/span>\u5206\u5b50\uff09\u3001\u5f3a\u5927\u589e\u6b96\u548c\u591a\u7cfb\u5206\u5316\u80fd\u529b\u3002\u5b83\u4eec\u5df2\u7528\u4e8e\u6cbb\u7597\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\u548c\u708e\u75c7\u6027\u75be\u75c5\uff0c\u5e76\u5728\u7ec8\u672b\u671f\u809d\u75c5\uff08\u5982\u5931\u4ee3\u507f\u6027\u809d\u786c\u5316\u548c\u6025\u6027\u52a0\u91cd\u578b\u6162\u6027\u809d\u8870\u7aed\uff09\u4e2d\u663e\u793a\u51fa\u6f5c\u529b\uff0c\u80fd\u8fc1\u79fb\u81f3\u635f\u4f24\u90e8\u4f4d\u53c2\u4e0e\u4fee\u590d\u3002<\/p>\n<p>\u622a\u81f32023\u5e74\u5e95\uff0c\u5df2\u6709\u8d85\u8fc71000\u9879\u76f8\u5173\u4e34\u5e8a\u8bd5\u9a8c\u6ce8\u518c\uff0c\u8bc1\u5b9e\u5176\u5728\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\u3001\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7b49\u75be\u75c5\u4e2d\u7684\u6cbb\u7597\u6f5c\u529b\uff0c\u5bf9\u7ec8\u672b\u671f\u809d\u75c5\u540c\u6837\u5c55\u73b0\u51fa\u5e94\u7528\u524d\u666f\u3002<\/p>\n<p>\u4f18\u52bf\u4e92\u8865\u4e0e\u4e34\u5e8a\u8f6c\u5316\u4e4b\u8def\uff1a\u603b\u4f53\u800c\u8a00\uff0c\u8fd9\u4e9b\u5e72\u7ec6\u80de\u79cd\u7c7b\u5404\u5177\u4f18\u52bf\u548c\u6311\u6218\uff1a\u809d\u810f\u6765\u6e90\u5e72\u7ec6\u80de\u66f4\u8d34\u8fd1\u751f\u7406\u518d\u751f\u4f46\u6548\u7387\u6709\u9650\uff1b\u80da\u80ce\u548c\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u591a\u80fd\u6027\u5f3a\u4f46\u5b89\u5168\u98ce\u9669\u7a81\u51fa\uff1b\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u514d\u75ab\u8c03\u8282\u80fd\u529b\u597d\u4f46\u9700\u4e2a\u4f53\u5316\u5e94\u7528\u3002<\/p>\n<p>\u672a\u6765\u7814\u7a76\u9700\u805a\u7126\u4e8e\u63d0\u9ad8\u79fb\u690d\u6548\u7387\u3001\u964d\u4f4e\u81f4\u7624\u98ce\u9669\u548c\u4f18\u5316\u60a3\u8005\u9009\u62e9\uff0c\u4ee5\u63a8\u52a8\u5e72\u7ec6\u80de\u7597\u6cd5\u5728\u809d\u810f\u75be\u75c5\u6cbb\u7597\u4e2d\u7684\u4e34\u5e8a\u8f6c\u5316\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%BB%88%E6%9C%AB%E6%9C%9F%E8%82%9D%E7%97%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%E5%92%8C%E5%8A%A8%E7%89%A9%E7%A0%94%E7%A9%B6\"><\/span><strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\u548c\u52a8\u7269\u7814\u7a76<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u672c\u7efc\u8ff0\u91cd\u70b9\u5173\u6ce8\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5728\u7ec8\u672b\u671f\u809d\u75c5\u4e2d\u7684\u4f5c\u7528\u4e0e\u6cbb\u7597\u6548\u679c\u3002\u901a\u8fc7PubMed\u6570\u636e\u5e93\u68c0\u7d22\uff0c\u5171\u53d1\u73b062\u9879\u76f8\u5173\u4e34\u5e8a\u8bd5\u9a8c\u53ca\u81ea2005\u5e74\u4ee5\u6765\u7684906\u9879\u52a8\u7269\u7814\u7a76\u3002\u88682\u4e0e\u88683\u7cfb\u7edf\u6c47\u603b\u4e86\u5176\u4e2d\u5177\u6709\u4ee3\u8868\u6027\u768415\u9879\u4e34\u5e8a\u8bd5\u9a8c\u4e0e10\u9879\u52a8\u7269\u7814\u7a76\u3002<\/p>\n<section>\n<div id=\"attachment_20708\" style=\"width: 2274px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20708\" class=\"wp-image-20708 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f1_Sheet131.png\" alt=\"\" width=\"2264\" height=\"2494\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f1_Sheet131.png 2264w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f1_Sheet131-272x300.png 272w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f1_Sheet131-930x1024.png 930w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f1_Sheet131-768x846.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f1_Sheet131-1394x1536.png 1394w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f1_Sheet131-1859x2048.png 1859w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f1_Sheet131-11x12.png 11w\" sizes=\"(max-width: 2264px) 100vw, 2264px\" \/><p id=\"caption-attachment-20708\" class=\"wp-caption-text\">\u88682\uff1a15\u9879\u5173\u4e8e\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\u7684\u4e34\u5e8a\u7814\u7a76<\/p><\/div>\n<\/section>\n<p>\u9488\u5bf9\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u5728\u809d\u810f\u75be\u75c5\u4e2d\u7684\u5e94\u7528\uff0c\u5df2\u5f00\u5c55\u4e86\u5927\u91cf\u4e34\u5e8a\u7814\u7a76\uff0c\u4e3b\u8981\u96c6\u4e2d\u5728\u8bd5\u9a8c\u8bbe\u8ba1\u3001\u7ec6\u80de\u6765\u6e90\u3001\u6ce8\u5c04\u9014\u5f84\u3001\u60a3\u8005\u4eba\u7fa4\u548c\u6cbb\u7597\u7ed3\u679c\u7b49\u65b9\u9762\u3002\u57fa\u4e8e\u8fd9\u4e9b\u65b9\u9762\uff0c\u6211\u4eec\u56de\u987e\u4e862007\u5e74\u81f32021\u5e74\u95f4\u603b\u7ed3MSCs\u5728\u809d\u810f\u75be\u75c5\u6cbb\u7597\u4e2d\u5e94\u7528\u768415\u7bc7\u6587\u7ae0\uff08\u88682\uff09\u3002<\/p>\n<p><strong>\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\u5b89\u5168\u6027\u53ca\u521d\u6b65\u7597\u6548<\/strong><\/p>\n<p>\u5171\u7eb3\u516515\u9879\u7814\u7a76\uff0c\u5305\u62ec4\u9879\u75c5\u4f8b\u7cfb\u5217\u7814\u7a76\u30016\u9879\u75c5\u4f8b\u5bf9\u7167\u7814\u7a76\u548c5\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff08RCT\uff09\u3002\u8fd915\u9879\u4e34\u5e8a\u7814\u7a76\u5171\u7eb3\u5165754\u540d\u60a3\u8005\uff0c\u6db5\u76d6\u5931\u4ee3\u507f\u6027\u809d\u786c\u5316\u3001\u6025\u6027\u52a0\u6162\u6027\u809d\u8870\u7aed\u3001\u81ea\u8eab\u514d\u75ab\u6027\u809d\u708e\u7b49\u591a\u79cd\u75be\u75c5\u7c7b\u578b\u3002\u7ec6\u80de\u6765\u6e90\u4ee5\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u4e3a\u4e3b\uff0c\u5176\u6b21\u4e3a\u8110\u5e26\u4e0e\u8102\u80aa\u6765\u6e90\u3002\u8f93\u6ce8\u9014\u5f84\u591a\u4e3a\u5916\u5468\u9759\u8109\u3002<\/p>\n<p>\u503c\u5f97\u5173\u6ce8\u7684\u662f\uff0c\u6240\u6709\u7814\u7a76\u5747\u672a\u62a5\u544a\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff0c14\u9879\u7814\u7a76\u663e\u793a\u60a3\u8005\u809d\u529f\u80fd\u4e0e\u751f\u6d3b\u8d28\u91cf\u5f97\u5230\u6539\u5584\uff0c\u5177\u4f53\u4f53\u73b0\u4e3a\u80c6\u78b1\u916f\u9176\u5347\u9ad8\u3001\u603b\u80c6\u7ea2\u7d20\u4e0b\u964d\u53caMELD\u8bc4\u5206\u6539\u5584\u3002\u90e8\u5206\u7814\u7a76\u8fd8\u89c2\u5bdf\u5230\u809d\u7ea4\u7ef4\u5316\u51cf\u8f7b\u3001\u751f\u5b58\u7387\u63d0\u9ad8\u53ca\u5e76\u53d1\u75c7\u51cf\u5c11\u3002<\/p>\n<p><strong>\u52a8\u7269\u7814\u7a76\u63ed\u793a\u7597\u6548\u4f18\u5316\u65b0\u7b56\u7565<\/strong><\/p>\n<p>\u8fd1\u5e74\u6765\uff0c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u7684\u4e34\u5e8a\u7814\u7a76\u9010\u6e10\u51cf\u5c11\uff0c\u52a8\u7269\u7814\u7a76\u7684\u62a5\u9053\u5219\u8d8a\u6765\u8d8a\u591a\u3002\u6211\u4eec\u603b\u7ed3\u4e862005\u5e74\u81f32014\u5e74\u95f4\u53d1\u8868\u768410\u7bc7\u5173\u4e8eMSCs\u6cbb\u7597\u809d\u8870\u7aed\u6216\u809d\u7ea4\u7ef4\u5316\u52a8\u7269\u6a21\u578b\u7684\u6587\u7ae0\uff08\u88683\uff09\u3002\u8d8a\u6765\u8d8a\u591a\u7684\u7814\u7a76\u91c7\u7528\u8054\u5408\u7597\u6cd5\u3001\u9884\u5904\u7406\u6216\u4fee\u9970MSCs\uff0c\u8868\u660e\u4eba\u4eec\u6b63\u52aa\u529b\u514b\u670dMSCs\u7684\u67d0\u4e9b\u5c40\u9650\u6027\u5e76\u63d0\u9ad8\u5176\u6cbb\u7597\u6548\u679c\u3002<\/p>\n<section>\n<div id=\"attachment_20704\" style=\"width: 1255px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20704\" class=\"wp-image-20704 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_115801_603.png\" alt=\"\" width=\"1245\" height=\"851\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_115801_603.png 1245w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_115801_603-300x205.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_115801_603-1024x700.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_115801_603-768x525.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-01_115801_603-18x12.png 18w\" sizes=\"(max-width: 1245px) 100vw, 1245px\" \/><p id=\"caption-attachment-20704\" class=\"wp-caption-text\">\u88683\uff1a\u5341\u9879\u5173\u4e8e\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\u7684\u4e34\u5e8a\u524d\u52a8\u7269\u7814\u7a76<\/p><\/div>\n<\/section>\n<p><strong>\u7cfb\u7edf\u5316\u6a21\u578b\u4e0e\u591a\u6837\u5316\u7ec6\u80de\u6765\u6e90\uff1a<\/strong>\u7814\u7a76\u591a\u91c7\u7528\u56db\u6c2f\u5316\u78b3\u3001\u4e8c\u7532\u57fa\u4e9a\u785d\u80fa\u7b49\u8bf1\u5bfc\u7684\u5927\u9f20\u6216\u5c0f\u9f20\u809d\u7ea4\u7ef4\u5316\u6a21\u578b\uff0c\u5e76\u4f7f\u7528\u5c0f\u9f20\u6216\u4eba\u6e90\u7684\u9aa8\u9ad3\u3001\u8110\u5e26\u3001\u534e\u901a\u6c0f\u80f6\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u3002\u521d\u6b65\u8bc1\u636e\u63d0\u793a\uff0c\u9aa8\u9ad3\u6765\u6e90\u7ec6\u80de\u53ef\u80fd\u56e0\u9ad8\u8868\u8fbe\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u9176\u800c\u5177\u5907\u66f4\u5f3a\u6297\u7ea4\u7ef4\u5316\u6f5c\u529b\u3002<\/p>\n<p><strong>\u5c3e\u9759\u8109\u6ce8\u5c04\u88ab\u9a8c\u8bc1\u4e3a\u6700\u4f18\u9014\u5f84\uff1a<\/strong>\u7814\u7a76\u8868\u660e\uff0c\u5c3e\u9759\u8109\u6ce8\u5c04\u5728\u4fc3\u8fdb\u7ec6\u80de\u5b9a\u690d\u548c\u6539\u5584\u7ea4\u7ef4\u5316\u65b9\u9762\u4f18\u4e8e\u8179\u8154\u4e0e\u809d\u5185\u6ce8\u5c04\uff0c\u5176\u673a\u5236\u53ef\u80fd\u4e0e\u8c03\u8282IL-10\u7b49\u56e0\u5b50\u6709\u5173\u3002<\/p>\n<p><strong>\u521b\u65b0\u7b56\u7565\u7a81\u7834\u7597\u6548\u74f6\u9888\uff1a<\/strong>\u4e3a\u63d0\u9ad8\u7ec6\u80de\u5b58\u6d3b\u4e0e\u5f52\u5de2\u6548\u7387\uff0c\u7814\u7a76\u5c1d\u8bd5\u4e86IL-6\u9884\u5904\u7406\u3001\u6297\u6c27\u5316\u5242\u5904\u7406\u3001\u57fa\u56e0\u8fc7\u8868\u8fbeCCR2\u3001PEG\u4fee\u9970\u7b49\u591a\u79cd\u65b9\u6cd5\uff0c\u663e\u8457\u63d0\u5347\u4e86\u6cbb\u7597\u6548\u679c\uff0c\u6807\u5fd7\u7740\u8be5\u9886\u57df\u5411\u7cbe\u51c6\u3001\u9ad8\u6548\u7684\u65b0\u4e00\u4ee3\u7597\u6cd5\u6f14\u8fdb\u3002<\/p>\n<p>\u603b\u4e4b\uff0c\u6240\u6709\u8fd9\u4e9b\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u5bf9\u809d\u75c5\u60a3\u8005\u5b89\u5168\u6709\u6548\uff0c\u5e76\u80fd\u6539\u5584\u809d\u529f\u80fd\u3002\u7136\u800c\uff0c\u5fc5\u987b\u627f\u8ba4\uff0c\u76ee\u524d\u5355\u7eaf\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6ce8\u5c04\u7597\u6cd5\u5df2\u65e0\u6cd5\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42\u3002\u5e78\u8fd0\u7684\u662f\uff0c\u4f17\u591a\u7814\u7a76\u4eba\u5458\u6b63\u79ef\u6781\u5e94\u7528\u65b0\u6280\u672f\u548c\u521b\u65b0\u65b9\u6cd5\uff0c\u5728\u79d1\u5b66\u8fdb\u6b65\u7684\u63a8\u52a8\u4e0b\uff0c\u4e3a\u8be5\u9886\u57df\u6ce8\u5165\u65b0\u7684\u6d3b\u529b\uff0c\u5e76\u63a8\u52a8\u5176\u53d1\u5c55\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%BB%88%E6%9C%AB%E6%9C%9F%E8%82%9D%E7%97%85%E7%9A%84%E6%A0%B8%E5%BF%83%E6%9C%BA%E5%88%B6\"><\/span><strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\u7684\u6838\u5fc3\u673a\u5236<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u9488\u5bf9MSC\u5728\u7ec8\u672b\u671f\u809d\u75c5\uff08ESLD\uff09\u4e2d\u7684\u6cbb\u7597\u673a\u5236\uff0c\u6211\u4eec\u57fa\u4e8e25\u9879\u4e34\u5e8a\u548c\u4e34\u5e8a\u524d\u7814\u7a76\u603b\u7ed3\u4e86\u4ee5\u4e0b\u56db\u79cd\u6838\u5fc3\u673a\u5236\uff08\u56fe2\uff09\u3002\u9700\u8981\u5f3a\u8c03\u7684\u662f\uff0c\u8fd9\u4e9b\u673a\u5236\u5177\u6709\u534f\u540c\u4f5c\u7528\uff0c\u52a8\u6001\u76f8\u4e92\u4f5c\u7528\uff0c\u5171\u540c\u6539\u5584\u809d\u529f\u80fd\u5e76\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\u3002<\/p>\n<section>\n<div id=\"attachment_20703\" style=\"width: 2018px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20703\" class=\"wp-image-20703 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_115857_287.png\" alt=\"\" width=\"2008\" height=\"1475\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_115857_287.png 2008w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_115857_287-300x220.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_115857_287-1024x752.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_115857_287-768x564.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_115857_287-1536x1128.png 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5fae\u4fe1\u56fe\u7247_2025-12-01_115857_287-16x12.png 16w\" sizes=\"(max-width: 2008px) 100vw, 2008px\" \/><p id=\"caption-attachment-20703\" class=\"wp-caption-text\">\u56fe2\uff1aMSC\u5728\u7ec8\u672b\u671f\u809d\u75c5\u4e2d\u7684\u6838\u5fc3\u673a\u5236<\/p><\/div>\n<\/section>\n<p><strong>1. 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\u514d\u75ab\u8c03\u8282\u673a\u5236\uff1a<\/strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u62e5\u6709\u5f3a\u5927\u7684\u514d\u75ab\u8c03\u8282\u80fd\u529b\uff0c\u901a\u8fc7\u8c03\u8282\u809d\u5185\u514d\u75ab\u7ec6\u80de\u548c\u5206\u6ccc\u6297\u708e\u56e0\u5b50\u6765\u51cf\u8f7b\u809d\u810f\u708e\u75c7\u3002\u5b83\u4eec\u80fd\u4fc3\u4f7f\u4fc3\u708e\u7684M1\u578b\u5de8\u566c\u7ec6\u80de\u5411\u6297\u708e\u7684M2\u578b\u8f6c\u5316\uff0c\u6291\u5236\u6811\u7a81\u72b6\u7ec6\u80de\u7684\u6210\u719f\u4e0e\u4fc3\u708e\u529f\u80fd\uff0c\u5e76\u8c03\u8282T\u6dcb\u5df4\u7ec6\u80de\u4e9a\u7fa4\u7684\u5e73\u8861\uff08\u5982\u63d0\u9ad8Treg\/Th17\u6bd4\u4f8b\uff09\u3002\u8fd9\u4e00\u7cfb\u5217\u4f5c\u7528\u521b\u9020\u4e86\u4e00\u4e2a\u6297\u708e\u3001\u4fc3\u4fee\u590d\u7684\u5fae\u73af\u5883\uff0c\u4ece\u6839\u6e90\u4e0a\u7f13\u89e3\u4e86\u9a71\u52a8\u809d\u7ea4\u7ef4\u5316\u548c\u635f\u4f24\u7684\u8fc7\u5ea6\u514d\u75ab\u53cd\u5e94\u3002<\/p>\n<p><strong>3. 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class=\"ez-toc-section\" id=\"%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%BB%88%E6%9C%AB%E6%9C%9F%E8%82%9D%E7%97%85%E7%9A%84%E5%9B%B0%E5%A2%83%E4%B8%8E%E6%9C%BA%E9%81%87\"><\/span><strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\u7684\u56f0\u5883\u4e0e\u673a\u9047<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>\u56f0\u5883\uff1a\u7597\u6548\u4e0d\u786e\u5b9a\u6027\u4e0e\u751f\u7269\u5b66\u74f6\u9888<\/strong><\/p>\n<p>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u9762\u4e34\u7684\u6838\u5fc3\u56f0\u5883\u5728\u4e8e\u5176\u7597\u6548\u7684\u4e0d\u786e\u5b9a\u6027\u548c\u53d8\u5f02\u6027\u3002\u4e0e\u809d\u79fb\u690d\uff08\u4e00\u5e74\u5b58\u6d3b\u7387\u7ea690%\uff0c\u4e94\u5e74\u7ea680%\uff09\u8fd9\u4e00\u6210\u719f\u4e14\u7597\u6548\u786e\u5207\u7684\u201c\u91d1\u6807\u51c6\u201d\u76f8\u6bd4\uff0c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u5c1a\u7f3a\u4e4f\u5927\u89c4\u6a21III\u671f\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u8bc1\u5b9e\u5176\u80fd\u6301\u7eed\u63d0\u9ad8\u60a3\u8005\u957f\u671f\u751f\u5b58\u7387\u3002<\/p>\n<p>\u5176\u6839\u672c\u539f\u56e0\u5728\u4e8e\u5173\u952e\u7684\u751f\u7269\u5b66\u74f6\u9888\uff1a\u4f53\u5185\u5f52\u5de2\u6548\u7387\u6781\u4f4e\u3002\u9759\u8109\u8f93\u6ce8\u540e\uff0c\u7edd\u5927\u591a\u6570\u7ec6\u80de\u4f1a\u6ede\u7559\u4e8e\u80ba\u90e8\u5e76\u572824\u5c0f\u65f6\u5185\u88ab\u6e05\u9664\uff0c\u65e0\u6cd5\u6709\u6548\u5230\u8fbe\u809d\u810f\u5e76\u957f\u671f\u5b58\u6d3b\u5b9a\u690d\u3002\u8fd9\u5bfc\u81f4\u5176\u7597\u6548\u4e3b\u8981\u4f9d\u8d56\u65c1\u5206\u6ccc\u548c\u514d\u75ab\u8c03\u8282\u7b49\u95f4\u63a5\u4f5c\u7528\uff0c\u800c\u975e\u6700\u521d\u671f\u5f85\u7684\u76f4\u63a5\u5206\u5316\u4e3a\u529f\u80fd\u809d\u7ec6\u80de\uff0c\u4ece\u800c\u9650\u5236\u4e86\u7597\u6548\u7684\u7a33\u5b9a\u6027\u548c\u5f3a\u5ea6\u3002<\/p>\n<p><strong>\u673a\u9047\uff1a\u4f5c\u7528\u673a\u5236\u7684\u65b0\u8ba4\u77e5\u4e0e\u201c\u7ec6\u80de\u836f\u7269\u201d\u5316<\/strong><\/p>\n<p>\u5c3d\u7ba1\u5f52\u5de2\u56f0\u96be\uff0c\u7814\u7a76\u63ed\u793a\u4e86\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u53d1\u6325\u4f5c\u7528\u7684\u72ec\u7279\u65b0\u673a\u5236\uff0c\u8fd9\u53cd\u800c\u6210\u4e3a\u5176\u53d1\u5c55\u7684\u673a\u9047\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u5373\u4f7f\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u8fc5\u901f\u53d1\u751f\u51cb\u4ea1\uff0c\u5176\u91ca\u653e\u7684\u51cb\u4ea1\u5c0f\u4f53\u88ab\u5de8\u566c\u7ec6\u80de\u7b49\u514d\u75ab\u7ec6\u80de\u541e\u566c\u540e\uff0c\u4e5f\u80fd\u8bf1\u5bfc\u540e\u8005\u5411\u6297\u708e\u3001\u4fc3\u4fee\u590d\u7684M2\u8868\u578b\u6781\u5316\uff0c\u5e76\u901a\u8fc7\u8868\u8fbeMMP12\u7b49\u57fa\u8d28\u964d\u89e3\u9176\u6765\u4fc3\u8fdb\u7ea4\u7ef4\u5316\u6d88\u9000\u3002\u8fd9\u4e00\u53d1\u73b0\u5c06\u7814\u7a76\u7126\u70b9\u4ece\u201c\u7ec6\u80de\u690d\u5165\u201d\u8f6c\u5411\u201c\u7ec6\u80de\u4f5c\u4e3a\u7cbe\u5bc6\u836f\u7269\u201d\u7684\u8303\u5f0f\uff0c\u5373\u4e0d\u5fc5\u5f3a\u6c42\u7ec6\u80de\u957f\u671f\u5b58\u6d3b\uff0c\u800c\u662f\u6700\u5927\u5316\u5176\u77ed\u6682\u5b58\u5728\u65f6\u7684\u514d\u75ab\u8c03\u8282\u4e0e\u4fe1\u53f7\u91ca\u653e\u529f\u80fd\u3002<\/p>\n<p><strong>\u673a\u9047\uff1a\u524d\u6cbf\u6280\u672f\u8d4b\u80fd\uff0c\u63d0\u5347\u7597\u6548\u4e0e\u7cbe\u51c6\u6027<\/strong><\/p>\n<p>\u4e3a\u514b\u670d\u56f0\u5883\uff0c\u4e00\u7cfb\u5217\u524d\u6cbf\u6280\u672f\u7b56\u7565\u5c55\u73b0\u51fa\u5de8\u5927\u6f5c\u529b\u3002\u8fd9\u5305\u62ec\uff1a<\/p>\n<ul class=\"list-paddingleft-1\">\n<li>\u57fa\u56e0\u5de5\u7a0b\uff1a\u901a\u8fc7\u6539\u9020\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff0c\u4f7f\u5176\u8fc7\u8868\u8fbe\u7279\u5b9a\u8d8b\u5316\u56e0\u5b50\u53d7\u4f53\uff08\u5982CXCR4\uff09\u4ee5\u589e\u5f3a\u5f52\u5de2\u80fd\u529b\uff0c\u6216\u4f7f\u5176\u6301\u7eed\u5206\u6ccc\u6cbb\u7597\u6027\u86cb\u767d\uff08\u5982IL-12\u3001\u5e72\u6270\u7d20-\u03b3\u7528\u4e8e\u6297\u80bf\u7624\uff1b\u786b\u6c27\u8fd8\u86cb\u767d-1\u7528\u4e8e\u6297\u6c27\u5316\uff09\uff0c\u5c06\u5176\u5347\u7ea7\u4e3a\u201c\u9776\u5411\u7ed9\u836f\u7cfb\u7edf\u201d\u3002<\/li>\n<\/ul>\n<ul class=\"list-paddingleft-1\">\n<li>\u8054\u5408\u7b56\u7565\uff1a\u5c06\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u4e0eIL-6\u7b49\u7ec6\u80de\u56e0\u5b50\u8054\u5408\u4f7f\u7528\uff0c\u6216\u5c06\u5176\u4e0e\u7eb3\u7c73\u751f\u7269\u6750\u6599\/\u77f3\u58a8\u70ef\u652f\u67b6\u7ed3\u5408\uff0c\u65e8\u5728\u6539\u5584\u7ec6\u80de\u5b58\u6d3b\u3001\u63d0\u4f9b\u652f\u6491\u5e76\u5b9e\u73b0\u751f\u957f\u56e0\u5b50\u7684\u53ef\u63a7\u91ca\u653e\uff0c\u4ece\u800c\u534f\u540c\u589e\u5f3a\u6cbb\u7597\u6548\u679c\u3002<\/li>\n<\/ul>\n<p><strong>\u673a\u9047\uff1a\u4e34\u5e8a\u7814\u7a76\u7a81\u7834\uff0c\u6307\u660e\u7cbe\u51c6\u7ed9\u836f\u65b9\u6848<\/strong><\/p>\n<p>\u6700\u8fd1\u7684\u5242\u91cf\u9012\u589e\u4e34\u5e8a\u7814\u7a76\u53d6\u5f97\u4e86\u5173\u952e\u7a81\u7834\uff0c\u5f00\u59cb\u56de\u7b54\u201c\u5982\u4f55\u7528\u836f\u201d\u8fd9\u4e00\u6838\u5fc3\u95ee\u9898\u3002\u7814\u7a76\u8bc1\u5b9e\uff0c\u9ad8\u5242\u91cf\uff08\u6bcf\u6b21\u6570\u4ebf\u7ec6\u80de\uff09\u3001\u91cd\u590d\uff08\u8fde\u7eed\u4e09\u5468\u6bcf\u5468\u4e00\u6b21\uff09\u9759\u8109\u8f93\u6ce8\u7684\u65b9\u6848\u5728\u5931\u4ee3\u507f\u6027\u809d\u786c\u5316\u60a3\u8005\u4e2d\u5b89\u5168\u53ef\u884c\uff0c\u5e76\u80fd\u8bf1\u5bfc\u51fa\u5f3a\u70c8\u7684\u3001\u7531\u7279\u5b9a\u5355\u6838\u7ec6\u80de\uff08\u5982MX1+\u5355\u6838\u7ec6\u80de\uff09\u4ecb\u5bfc\u7684\u514d\u75ab\u8c03\u8282\u6548\u5e94\u3002<\/p>\n<p>\u8be5\u7814\u7a76\u9996\u6b21\u5728\u4eba\u4f53\u4e2d\u660e\u786e\u4e86\u5242\u91cf-\u65f6\u95f4-\u6548\u5e94\u5173\u7cfb\uff0c\u4e3a\u8bbe\u8ba1\u5927\u89c4\u6a21II\/III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u63d0\u4f9b\u4e86\u81f3\u5173\u91cd\u8981\u7684\u79d1\u5b66\u4f9d\u636e\u548c\u4f18\u5316\u7ed9\u836f\u7b56\u7565\uff0c\u6781\u5927\u5730\u589e\u52a0\u4e86\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u672a\u6765\u88ab\u7eb3\u5165\u4e34\u5e8a\u6307\u5357\u7684\u53ef\u80fd\u6027\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E6%80%BB%E7%BB%93\"><\/span><strong>\u603b\u7ed3<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\u6b63\u5904\u5173\u952e\u8f6c\u6298\u70b9\u3002\u5176\u5f53\u524d\u56f0\u5883\u5728\u4e8e\u7597\u6548\u786e\u5b9a\u6027\u4e0d\u8db3\u4e0e\u751f\u7269\u5b66\u7279\u6027\u9650\u5236\uff1b\u800c\u672a\u6765\u673a\u9047\u5219\u6e90\u4e8e\u5bf9\u4f5c\u7528\u673a\u5236\u7684\u6df1\u5316\u8ba4\u77e5\u3001\u57fa\u56e0\u4e0e\u6750\u6599\u6280\u672f\u7684\u8d4b\u80fd\u4ee5\u53ca\u4e34\u5e8a\u7ed9\u836f\u65b9\u6848\u7684\u7a81\u7834\u3002<\/p>\n<p>\u672a\u6765\u7684\u6210\u529f\uff0c\u5fc5\u5c06\u4f9d\u8d56\u4e8e\u5145\u5206\u5229\u7528\u8fd9\u4e9b\u673a\u9047\uff0c\u901a\u8fc7\u7cbe\u51c6\u7684\u5de5\u7a0b\u5316\u6539\u9020\u4e0e\u4f18\u5316\u7684\u4e34\u5e8a\u7b56\u7565\uff0c\u6700\u7ec8\u5c06\u5176\u8f6c\u5316\u4e3a\u4e00\u79cd\u53ef\u9760\u3001\u9ad8\u6548\u7684\u201c\u6d3b\u7ec6\u80de\u836f\u7269\u201d\uff0c\u4e3a\u7ec8\u672b\u671f\u809d\u75c5\u60a3\u8005\u5e26\u6765\u65b0\u7684\u5e0c\u671b\u3002<\/p>\n<\/section>\n<\/section>\n<blockquote><p>\u53c2\u8003\u8d44\u6599\uff1a<\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[1] <\/span><\/span><span data-pm-slice=\"0 0 []\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Li, S., Wang, Y., Li, Sm.\u00a0<\/span><\/span><\/span><i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7b49.<\/span><\/span><\/i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u00a0\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\uff1a\u6311\u6218\u4e0e\u673a\u9047.\u00a0<\/span><\/span><i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597<\/span><\/span><\/i>\u00a0<b><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">16<\/span><\/span><\/b><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> , 666 (2025). https:\/\/doi.org\/10.1186\/s13287-025-04788-3<\/span><\/span><\/p>\n<p>\u514d\u8d23\u8bf4\u660e\uff1a\u672c\u6587\u4ec5\u7528\u4e8e\u4f20\u64ad\u79d1\u666e\u77e5\u8bc6\uff0c\u5206\u4eab\u884c\u4e1a\u89c2\u70b9\uff0c\u4e0d\u6784\u6210\u4efb\u4f55\u4e34\u5e8a\u8bca\u65ad\u5efa\u8bae\uff01\u676d\u5409\u5e72\u7ec6\u80de\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4e0d\u80fd\u66ff\u4ee3\u533b\u751f\u6216\u836f\u5242\u5e08\u7684\u4e13\u4e1a\u5efa\u8bae\u3002\u5982\u6709\u7248\u6743\u7b49\u7591\u95ee\uff0c\u8bf7\u968f\u65f6\u8054\u7cfb\u6211\u3002<\/p><\/blockquote>","protected":false},"excerpt":{"rendered":"<p>\u8fd1\u5e74\u6765\uff0c\u7ec8\u672b\u671f\u809d\u75c5\u5df2\u6210\u4e3a\u5168\u7403\u8303\u56f4\u5185\u9ad8\u53d1\u75c5\u7387\u4e0e\u9ad8\u6b7b\u4ea1\u7387\u7684\u4e3b\u8981\u75be\u75c5\u4e4b\u4e00\uff0c\u5176\u75c5\u56e0\u591a\u6837\uff0c\u5305\u62ec\u9152\u7cbe\u6027\u809d\u75c5\u3001\u75c5\u6bd2\u6027\u809d\u708e\u3001\u975e [&hellip;]<\/p>","protected":false},"author":1,"featured_media":20702,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[76],"tags":[244,178],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts\/20701"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/comments?post=20701"}],"version-history":[{"count":1,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts\/20701\/revisions"}],"predecessor-version":[{"id":20709,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts\/20701\/revisions\/20709"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/media\/20702"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/media?parent=20701"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/categories?post=20701"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/tags?post=20701"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}