{"id":20848,"date":"2025-12-10T15:24:21","date_gmt":"2025-12-10T07:24:21","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=20848"},"modified":"2025-12-10T15:26:44","modified_gmt":"2025-12-10T07:26:44","slug":"https-www-hjtdsm-cn-stem-cells-stem-cell-therapy-20848-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20848.html","title":{"rendered":"\u9759\u8109\u6ce8\u5c04\u4eba\u7259\u9ad3\u5e72\u7ec6\u80de\u6cbb\u7597\u4ea8\u5ef7\u987f\u75c5\u7684I\u671f\u7814\u7a76\uff1a\u8bc4\u4f30\u4e24\u79cd\u5242\u91cf\u6c34\u5e73\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u4e0e\u521d\u6b65\u7597\u6548"},"content":{"rendered":"<p>\u8fd1\u671f\uff0c\u56fd\u9645\u671f\u520a\u6742\u5fd7\u300a<span dir=\"auto\">\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u300b\u53d1\u8868\u4e86\u4e00\u7bc7\u201c<a href=\"https:\/\/link.springer.com\/article\/10.1186\/s13287-025-04703-w\" target=\"_blank\" rel=\"noopener nofollow\">\u4e00\u9879\u9488\u5bf9\u4ea8\u5ef7\u987f\u75c5\u60a3\u8005\u91c7\u7528\u4e24\u79cd\u5242\u91cf\u6c34\u5e73\u7684\u9759\u8109\u6ce8\u5c04\u4eba\u7259\u9ad3\u5e72\u7ec6\u80de\uff08NestaCell\u00ae\uff09\u7684I\u671f\u5f00\u653e\u6807\u7b7e\u7814\u7a76<\/a>\u201d\u7684\u7efc\u8ff0\u3002\u8fd9\u9879\u524d\u77bb\u6027\u3001\u5f00\u653e\u6807\u7b7e\u3001\u5355\u4e2d\u5fc3\u3001\u9996\u6b21\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\u8bc4\u4f30\u4e86\u9759\u8109\u6ce8\u5c04\u7259\u9ad3\u5e72\u7ec6\u80de\u6cbb\u7597\u4ea8\u5ef7\u987f\u75c5\u60a3\u8005\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u521d\u6b65\u7597\u6548<sup>[1]<\/sup>\u3002<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-20849 aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_150013_451.png\" alt=\"\" width=\"730\" height=\"443\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_150013_451.png 730w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_150013_451-300x182.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_150013_451-18x12.png 18w\" sizes=\"(max-width: 730px) 100vw, 730px\" \/><\/p>\n<p><span dir=\"auto\">\u7ed3\u679c\u521d\u6b65\u7597\u6548\u5206\u6790\u8868\u660e\uff0c<\/span>NestaCell\u00ae\u5728\u4ea8\u5ef7\u987f\u75c5\u60a3\u8005\u4e2d\u5c55\u73b0\u51fa\u826f\u597d\u7684\u5b89\u5168\u6027\uff0c\u5373\u4f7f\u5728\u957f\u8fbe\u4e94\u5e74\u7684\u591a\u6b21\u7ed9\u836f\u540e\uff0c\u4e5f\u672a\u53d1\u751f\u4e0e\u6cbb\u7597\u76f8\u5173\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002\u8f7b\u5fae\u4e0d\u826f\u4e8b\u4ef6\uff08\u5982\u6682\u65f6\u6027\u6bdb\u53d1\u8272\u7d20\u6c89\u7740\uff09\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u89c2\u5bdf\u5230\u81f4\u7624\u6027\u6216\u663e\u8457\u514d\u75ab\u539f\u6027\u53cd\u5e94\u3002\u4e34\u5e8a\u83b7\u76ca\u4f53\u73b0\u5728\u7edf\u4e00\u4ea8\u5ef7\u987f\u75c5\u8bc4\u5b9a\u91cf\u8868\u603b\u8fd0\u52a8\u8bc4\u5206\u548c\u603b\u529f\u80fd\u80fd\u529b\u8bc4\u5206\u7684\u7a33\u5b9a\u6216\u6539\u5584\uff0c\u652f\u6301\u5f00\u5c55\u66f4\u5927\u89c4\u6a21\u8bd5\u9a8c\u4ee5\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u5176\u7597\u6548\u3002<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" 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href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20848.html\/#%E6%96%B9%E6%B3%95%EF%BC%9A%E7%A0%94%E7%A9%B6%E8%AE%BE%E8%AE%A1%E4%B8%8E%E8%AF%84%E4%BC%B0\" >\u65b9\u6cd5\uff1a\u7814\u7a76\u8bbe\u8ba1\u4e0e\u8bc4\u4f30<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20848.html\/#%E7%89%99%E9%AB%93%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E4%BA%A8%E5%BB%B7%E9%A1%BF%E7%97%85%E7%9A%84%E7%BB%93%E6%9E%9C\" >\u7259\u9ad3\u5e72\u7ec6\u80de\u6cbb\u7597\u4ea8\u5ef7\u987f\u75c5\u7684\u7ed3\u679c<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20848.html\/#%E7%A0%94%E7%A9%B6%E4%BA%BA%E7%BE%A4\" >\u7814\u7a76\u4eba\u7fa4<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20848.html\/#%E6%8E%A5%E5%8F%97%E6%83%85%E5%86%B5\" >\u63a5\u53d7\u60c5\u51b5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20848.html\/#%E5%AE%89%E5%85%A8%E6%83%85%E5%86%B5\" >\u5b89\u5168\u60c5\u51b5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20848.html\/#%E7%96%97%E6%95%88%E6%96%B9%E9%9D%A2\" >\u7597\u6548\u65b9\u9762<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20848.html\/#%E8%AE%A8%E8%AE%BA\" >\u8ba8\u8bba<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/stem-cell-therapy\/20848.html\/#%E7%BB%93%E8%AE%BA\" >\u7ed3\u8bba<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"ds-markdown-paragraph\"><span class=\"ez-toc-section\" id=\"%E7%A0%94%E7%A9%B6%E8%83%8C%E6%99%AF%E4%B8%8E%E4%BA%A7%E5%93%81%E7%89%B9%E6%80%A7\"><\/span><strong>\u7814\u7a76\u80cc\u666f\u4e0e\u4ea7\u54c1\u7279\u6027<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"ds-markdown-paragraph\">\u4ea8\u5ef7\u987f\u75c5\uff08HD\uff09\u662f\u4e00\u79cd\u8fdb\u884c\u6027<a href=\"https:\/\/www.hjtdsm.cn\/ar\/stem-cells\/nsc\/19258.html\/\" target=\"_blank\" rel=\"noopener\">\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5<\/a>\uff0c\u76ee\u524d\u5c1a\u65e0\u83b7\u6279\u7684\u75be\u75c5\u4fee\u9970\u7597\u6cd5\u3002\u4eba\u7259\u9ad3\u5e72\u7ec6\u80de\uff08hDPSCs\uff09\u56e0\u5176\u795e\u7ecf\u53d1\u751f\u3001\u795e\u7ecf\u8425\u517b\u548c\u514d\u75ab\u8c03\u8282\u7279\u6027\u800c\u5177\u6709\u6f5c\u5728\u7684\u6cbb\u7597\u4ef7\u503c\u3002\u4e0e\u5176\u4ed6\u6765\u6e90\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u76f8\u6bd4\uff0chDPSCs\u5728\u589e\u6b96\u901f\u5ea6\u3001\u5206\u5316\u80fd\u529b\u548c\u83b7\u53d6\u4fbf\u5229\u6027\u65b9\u9762\u66f4\u5177\u4f18\u52bf\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20857 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-920449100-612x612-1.jpg\" alt=\"\u9759\u8109\u6ce8\u5c04\u4eba\u7259\u9ad3\u5e72\u7ec6\u80de\u6cbb\u7597\u4ea8\u5ef7\u987f\u75c5\u7684I\u671f\u7814\u7a76\uff1a\u8bc4\u4f30\u4e24\u79cd\u5242\u91cf\u6c34\u5e73\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u4e0e\u521d\u6b65\u7597\u6548\" width=\"612\" height=\"407\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-920449100-612x612-1.jpg 612w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-920449100-612x612-1-300x200.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-920449100-612x612-1-18x12.jpg 18w\" sizes=\"(max-width: 612px) 100vw, 612px\" \/><\/p>\n<p class=\"ds-markdown-paragraph\">\u672c\u7814\u7a76\u91c7\u7528\u7684NestaCell\u00ae\u662f\u4e00\u79cd\u7531\u51b7\u51bb\u4fdd\u5b58\u7684hDPSCs\u60ac\u6d6e\u4e8e\u65e0\u83cc\u751f\u7406\u76d0\u6c34\u4e2d\u7ec4\u6210\u7684\u65b0\u578b\u4ea7\u54c1\u3002\u5b83\u9ad8\u8868\u8fbe\u5de2\u86cb\u767d\u5e76\u5206\u6ccc\u9ad8\u6c34\u5e73\u7684\u8111\u6e90\u6027\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff0c\u4e14\u56e0HLA-DR\u6297\u539f\u4f4e\u8868\u8fbe\uff0c\u53ef\u5b89\u5168\u7528\u4e8e\u5f02\u4f53\u79fb\u690d\u800c\u65e0\u9700\u514d\u75ab\u6291\u5236\u3002\u8f6c\u5f55\u7ec4\u5206\u6790\u663e\u793a\u5176\u5177\u6709\u72ec\u7279\u7684\u4fc3\u8fdb\u8f74\u7a81\u751f\u957f\u7684\u57fa\u56e0\u8868\u8fbe\u8c31\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u8868\u660e\uff0c\u9759\u8109\u6ce8\u5c04\u7684NestaCell\u00ae\u80fd\u5728\u4ea8\u5ef7\u987f\u75c5\u6a21\u578b\u52a8\u7269\u4e2d\u4fc3\u8fdb\u5173\u952e\u795e\u7ecf\u6807\u5fd7\u7269\u8868\u8fbe\uff0c\u5e76\u8fc1\u79fb\u81f3\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\uff0c\u4e14\u5728\u9ad8\u5242\u91cf\u4e0b\u8010\u53d7\u6027\u826f\u597d\u3002<\/p>\n<p class=\"ds-markdown-paragraph\">\u9274\u4e8e\u6b64\uff0c\u6211\u4eec\u8fdb\u884c\u4e86\u4e00\u9879\u524d\u77bb\u6027\u3001\u5f00\u653e\u6807\u7b7e\u3001\u5355\u4e2d\u5fc3\u7684\u9996\u6b21\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u65e8\u5728\u8bc4\u4f30\u9759\u8109\u6ce8\u5c04NestaCell\u00ae\u5728HD\u60a3\u8005\u4e2d\u7684\u957f\u671f\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u521d\u6b65\u7597\u6548\u53ca\u514d\u75ab\u5b66\u6548\u5e94\u3002<\/p>\n<h2 class=\"ds-markdown-paragraph\"><span class=\"ez-toc-section\" id=\"%E6%96%B9%E6%B3%95%EF%BC%9A%E7%A0%94%E7%A9%B6%E8%AE%BE%E8%AE%A1%E4%B8%8E%E8%AF%84%E4%BC%B0\"><\/span><strong>\u65b9\u6cd5\uff1a\u7814\u7a76\u8bbe\u8ba1\u4e0e\u8bc4\u4f30<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong>\u7814\u7a76\u8bbe\u8ba1\u4e0e\u53d7\u8bd5\u8005\uff1a<\/strong>\u672c\u7814\u7a76\u91c7\u7528\u5206\u9636\u6bb5\u5242\u91cf\u9012\u589e\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u3002\u62db\u52df\u4e8621-65\u5c81\u3001\u643a\u5e26\u7279\u5b9aCAG\u91cd\u590d\u5e8f\u5217\u7684\u7537\u6027\u4ea8\u5ef7\u987f\u75c5\u60a3\u8005\u3002\u7ed9\u836f\u4e25\u683c\u9075\u5faa\u5206\u9636\u6bb5\u539f\u5219\uff1a\u9996\u540d\u53d7\u8bd5\u8005\u63a5\u53d7\u4f4e\u5242\u91cf\uff08100\u4e07\u7ec6\u80de\/\u516c\u65a4\uff09\u6cbb\u7597\uff0c\u7ecf\u81f3\u5c1130\u5929\u89c2\u5bdf\u786e\u8ba4\u5b89\u5168\u6027\u540e\uff0c\u518d\u7eb3\u5165\u540e\u7eed\u53d7\u8bd5\u8005\u3002\u4f4e\u5242\u91cf\u7ec4\u5b8c\u6210\u5e76\u7ecf\u5b89\u5168\u59d4\u5458\u4f1a\u5ba1\u67e5\u540e\uff0c\u65b9\u542f\u52a8\u9ad8\u5242\u91cf\u7ec4\uff08200\u4e07\u7ec6\u80de\/\u516c\u65a4\uff09\u7814\u7a76\u3002\u521d\u59cb\u65b9\u6848\u4e3a\u4e09\u4e2a\u6708\u5185\u4e09\u6b21\u7ed9\u836f\uff0c\u57fa\u4e8e\u4e2d\u671f\u5b89\u5168\u6027\u6570\u636e\uff0c\u65b9\u6848\u4fee\u8ba2\u5141\u8bb8\u5728\u4e94\u5e74\u968f\u8bbf\u671f\u5185\u589e\u52a0\u7ed9\u836f\u6b21\u6570\u3002<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u7ec6\u80de\u5236\u5907\u4e0e\u8d28\u91cf\u63a7\u5236\uff1a<\/strong>NestaCell\u00ae\u6765\u6e90\u4e8e\u5065\u5eb7\u513f\u7ae5\u6350\u732e\u7684\u4e73\u7259\uff0c\u5728\u7b26\u5408\u836f\u54c1\u751f\u4ea7\u8d28\u91cf\u7ba1\u7406\u89c4\u8303\u6761\u4ef6\u4e0b\u5206\u79bb\u3001\u57f9\u517b\u5e76\u5efa\u7acb\u7ec6\u80de\u5e93\u3002\u4ea7\u54c1\u653e\u884c\u524d\u7ecf\u8fc7\u4e25\u683c\u68c0\u6d4b\uff0c\u5305\u62ec\u7ec6\u80de\u6d3b\u529b\u3001\u8868\u9762\u6807\u5fd7\u7269\uff08CD90\u3001CD73\u9ad8\u8868\u8fbe\uff0cHLA-DR\u4f4e\u8868\u8fbe\uff09\u3001BDNF\u5206\u6ccc\u80fd\u529b\u3001\u65e0\u83cc\u6027\u53ca\u5185\u6bd2\u7d20\u7b49\uff0c\u786e\u4fdd\u5176\u5b89\u5168\u6027\u548c\u529f\u80fd\u6027\u3002<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u5b89\u5168\u6027\u53ca\u7597\u6548\u8bc4\u4f30\uff1a<\/strong>\u5b89\u5168\u6027\u8bc4\u4f30\u5305\u62ec\u7ed9\u836f\u540e48\u5c0f\u65f6\u5bc6\u96c6\u76d1\u6d4b\u3001\u5b9a\u671f\u4f53\u683c\u68c0\u67e5\u3001\u5b9e\u9a8c\u5ba4\u68c0\u67e5\uff08\u91cd\u70b9\u5173\u6ce8\u809d\u529f\u80fd\u548c\u514d\u75ab\u53c2\u6570\uff09\u3001\u4ee5\u53ca\u957f\u8fbe\u56db\u5e74\u7684\u80bf\u7624\u7b5b\u67e5\u3002\u7597\u6548\u901a\u8fc7\u7edf\u4e00\u4ea8\u5ef7\u987f\u75c5\u8bc4\u5b9a\u91cf\u8868\u603b\u8fd0\u52a8\u8bc4\u5206\u548c\u603b\u529f\u80fd\u80fd\u529b\u8bc4\u5206\u7684\u53d8\u5316\u8fdb\u884c\u8bc4\u4f30\u3002\u514d\u75ab\u5b66\u6548\u5e94\u901a\u8fc7\u76d1\u6d4bCD4\/CD8\u6dcb\u5df4\u7ec6\u80de\u8ba1\u6570\u53ca\u7279\u5b9a\u708e\u75c7\u7ec6\u80de\u56e0\u5b50\u6c34\u5e73\u6765\u63a2\u8ba8\u3002<\/p>\n<h2 id=\"Sec7\" class=\"c-article-section__title js-section-title js-c-reading-companion-sections-item\"><span class=\"ez-toc-section\" id=\"%E7%89%99%E9%AB%93%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E4%BA%A8%E5%BB%B7%E9%A1%BF%E7%97%85%E7%9A%84%E7%BB%93%E6%9E%9C\"><\/span><span dir=\"auto\">\u7259\u9ad3\u5e72\u7ec6\u80de\u6cbb\u7597\u4ea8\u5ef7\u987f\u75c5\u7684\u7ed3\u679c<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<div id=\"Sec7-content\" class=\"c-article-section__content\">\n<h3 id=\"Sec8\" class=\"c-article__sub-heading\"><span class=\"ez-toc-section\" id=\"%E7%A0%94%E7%A9%B6%E4%BA%BA%E7%BE%A4\"><\/span><span dir=\"auto\">\u7814\u7a76\u4eba\u7fa4<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\">\u672c\u8bd5\u9a8c\u5171\u7b5b\u9009\u4e867\u540d\u60a3\u8005\uff0c\u968f\u540e\u7eb3\u51656\u540d\u3002\u6240\u6709\u5165\u7ec4\u60a3\u8005\u5747\u5b8c\u6210\u4e86\u4e3a\u671f\u4e24\u5e74\u7684\u968f\u8bbf\uff1b\u5176\u4e2d5\u540d\u5b8c\u6210\u4e86\u4e09\u5e74\u968f\u8bbf\uff0c4\u540d\u5b8c\u6210\u4e86\u56db\u5e74\u968f\u8bbf\uff0c2\u540d\u5b8c\u6210\u4e86\u6574\u4e2a\u4e94\u5e74\u8bd5\u9a8c\u30024\u540d\u60a3\u8005\u63d0\u524d\u9000\u51fa\u8bd5\u9a8c\uff1a1\u540d\u60a3\u8005\u56e0\u5728100\u4e07\u7ec6\u80de\/\u516c\u65a4\u5242\u91cf\u4e0b\u53d1\u751f\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff08\u80ba\u764c\uff0c\u7814\u7a76\u8005\u7ec8\u6b62\u8bd5\u9a8c\uff09\uff0c1\u540d\u60a3\u8005\u5931\u8bbf\uff0c2\u540d\u60a3\u8005\u64a4\u56de\u77e5\u60c5\u540c\u610f\uff08\u56fe1<\/span><span dir=\"auto\">\uff09\u3002\u60a3\u8005\u7684\u57fa\u7ebf\u4eba\u53e3\u7edf\u8ba1\u5b66\u7279\u5f81\u548cUHDRS\u8bc4\u5206\u6c47\u603b\u4e8e\u88681<\/span><span dir=\"auto\">\u3002<\/span><\/p>\n<div id=\"attachment_20856\" style=\"width: 695px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20856\" class=\"wp-image-20856 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/13287_2025_4703_Fig2_HTML.png\" alt=\"\" width=\"685\" height=\"343\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/13287_2025_4703_Fig2_HTML.png 685w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/13287_2025_4703_Fig2_HTML-300x150.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/13287_2025_4703_Fig2_HTML-18x9.png 18w\" sizes=\"(max-width: 685px) 100vw, 685px\" \/><p id=\"caption-attachment-20856\" class=\"wp-caption-text\">\u56fe1\uff1a\u7814\u7a76\u6d41\u7a0b\u56fe\u3002<\/p><\/div>\n<div id=\"attachment_20853\" style=\"width: 1143px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20853\" class=\"wp-image-20853 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143716_289.png\" alt=\"\" width=\"1133\" height=\"329\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143716_289.png 1133w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143716_289-300x87.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143716_289-1024x297.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143716_289-768x223.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143716_289-18x5.png 18w\" sizes=\"(max-width: 1133px) 100vw, 1133px\" \/><p id=\"caption-attachment-20853\" class=\"wp-caption-text\">\u88681\u6bcf\u4f4d\u60a3\u8005\u7684\u4eba\u53e3\u7edf\u8ba1\u5b66\u57fa\u7ebf\u7279\u5f81\uff08V-1\uff09<\/p><\/div>\n<h3 id=\"Sec9\" class=\"c-article__sub-heading\"><span class=\"ez-toc-section\" id=\"%E6%8E%A5%E5%8F%97%E6%83%85%E5%86%B5\"><\/span><span dir=\"auto\">\u63a5\u53d7\u60c5\u51b5<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\">\u88682<\/span><span dir=\"auto\">\u603b\u7ed3\u4e86\u60a3\u8005\u63a5\u53d7NestaCell\u00ae\u6cbb\u7597\u7684\u60c5\u51b5\uff0c\u5171\u8fdb\u884c\u4e86102\u6b21\u7ed9\u836f\uff1a\u5176\u4e2d31\u6b21\u5242\u91cf\u4e3a100\u4e07\u4e2a\u7ec6\u80de\/\u516c\u65a4\uff0c71\u6b21\u5242\u91cf\u4e3a200\u4e07\u4e2a\u7ec6\u80de\/\u516c\u65a4\u3002P3\u63a5\u53d7\u4e86\u4e00\u6b21\u957f\u671f\u7ed9\u836f\uff0c21\u5929\u540e\u505c\u6b62\u6cbb\u7597\u3002<\/span><\/p>\n<div id=\"attachment_20852\" style=\"width: 1139px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20852\" class=\"wp-image-20852 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143740_353.png\" alt=\"\" width=\"1129\" height=\"210\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143740_353.png 1129w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143740_353-300x56.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143740_353-1024x190.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143740_353-768x143.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143740_353-18x3.png 18w\" sizes=\"(max-width: 1129px) 100vw, 1129px\" \/><p id=\"caption-attachment-20852\" class=\"wp-caption-text\">\u88682\u7814\u7a76\u4ea7\u54c1\u7684\u66b4\u9732\u60c5\u51b5\uff0c\u4ee5NestaCell\u00ae\u7ed9\u836f\u6b21\u6570\u786e\u5b9a<\/p><\/div>\n<h3><span class=\"ez-toc-section\" id=\"%E5%AE%89%E5%85%A8%E6%83%85%E5%86%B5\"><\/span>\u5b89\u5168\u60c5\u51b5<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\">\u88683<\/span><span dir=\"auto\">\u663e\u793a\u4e86\u6309\u5f3a\u5ea6\u548c\u4e0e\u7814\u7a76\u4ea7\u54c1\u7684\u5173\u7cfb\u5206\u7c7b\u7684\u6cbb\u7597\u671f\u95f4\u51fa\u73b0\u7684\u4e0d\u826f\u4e8b\u4ef6 (TEAE)\uff0c\u00a0\u800c\u8868<\/span><span dir=\"auto\">4<\/span><span dir=\"auto\">\u8be6\u7ec6\u5217\u51fa\u4e86\u6240\u6709\u62a5\u544a\u7684TEAE\u00a0\u00a0\u3002<\/span><\/p>\n<div id=\"attachment_20851\" style=\"width: 1138px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20851\" class=\"wp-image-20851 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143809_290.png\" alt=\"\" width=\"1128\" height=\"356\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143809_290.png 1128w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143809_290-300x95.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143809_290-1024x323.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143809_290-768x242.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143809_290-18x6.png 18w\" sizes=\"(max-width: 1128px) 100vw, 1128px\" \/><p id=\"caption-attachment-20851\" class=\"wp-caption-text\">\u88684 \u6309\u56e0\u679c\u5173\u7cfb\u3001\u5f3a\u5ea6\u548c\u4e25\u91cd\u7a0b\u5ea6\u5206\u7c7b\u7684\u6cbb\u7597\u671f\u95f4\u51fa\u73b0\u7684\u4e0d\u826f\u4e8b\u4ef6\uff08TEAE\uff09\u3002<\/p><\/div>\n<p>&nbsp;<\/p>\n<div id=\"attachment_20850\" style=\"width: 1138px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20850\" class=\"wp-image-20850 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143821_426.png\" alt=\"\" width=\"1128\" height=\"494\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143821_426.png 1128w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143821_426-300x131.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143821_426-1024x448.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143821_426-768x336.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-10_143821_426-18x8.png 18w\" sizes=\"(max-width: 1128px) 100vw, 1128px\" \/><p id=\"caption-attachment-20850\" class=\"wp-caption-text\">\u88684\uff1a\u6309\u53d7\u5f71\u54cd\u5668\u5b98\u7c7b\u522b\u5212\u5206\u7684\u6cbb\u7597\u671f\u95f4\u51fa\u73b0\u7684\u4e0d\u826f\u4e8b\u4ef6 (TEAE)\uff0c\u5b9a\u4e49\u89c1\u533b\u5b66\u672f\u8bed\u96c6 (MedDRA\uff0c\u7248\u672c 24.1\uff0c2021 \u5e74 9 \u6708)<\/p><\/div>\n<p 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class=\"ds-markdown-paragraph\">\u57fa\u4e8e\u4ee4\u4eba\u9f13\u821e\u7684\u5b89\u5168\u6027\u548c\u521d\u6b65\u7597\u6548\u8bc1\u636e\uff0c\u7814\u7a76\u65b9\u6848\u5728\u968f\u8bbf\u671f\u5185\u4fee\u8ba2\u589e\u52a0\u4e86\u7ed9\u836f\u6b21\u6570\u3002\u4e24\u79cd\u5242\u91cf\u7ec4\u5747\u663e\u793a\u51fa\u6f5c\u5728\u4e34\u5e8a\u83b7\u76ca\uff0c\u4f53\u73b0\u4e3a\u7edf\u4e00\u4ea8\u5ef7\u987f\u75c5\u8bc4\u5b9a\u91cf\u8868\u7684\u603b\u8fd0\u52a8\u8bc4\u5206\u548c\u603b\u529f\u80fd\u80fd\u529b\u8bc4\u5206\u7684\u7a33\u5b9a\u6216\u6539\u5584\u3002\u8fd9\u4e3a\u672a\u6765\u8fdb\u4e00\u6b65\u63a2\u7d22\u5e72\u7ec6\u80de\u6cbb\u7597\u5728\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u4e2d\u7684\u5e94\u7528\u63d0\u4f9b\u4e86\u6709\u76ca\u53c2\u8003\u3002<\/p>\n<h2 id=\"Sec13\" class=\"c-article-section__title js-section-title js-c-reading-companion-sections-item\"><span class=\"ez-toc-section\" id=\"%E7%BB%93%E8%AE%BA\"><\/span><span dir=\"auto\">\u7ed3\u8bba<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<div id=\"Sec13-content\" class=\"c-article-section__content\">\n<p><span dir=\"auto\">NestaCell\u00ae\u5c55\u73b0\u51fa\u826f\u597d\u7684\u5b89\u5168\u6027\uff0c\u5373\u4f7f\u5728\u957f\u8fbe\u4e94\u5e74\u7684\u5e7f\u6cdb\u7528\u836f\u540e\uff0c\u4e5f\u672a\u53d1\u751f\u4e0e\u6cbb\u7597\u76f8\u5173\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002\u8f7b\u5fae\u4e0d\u826f\u4e8b\u4ef6\uff0c\u4f8b\u5982\u6682\u65f6\u6027\u6bdb\u53d1\u8272\u7d20\u6c89\u7740\u53d8\u5316\uff0c\u8010\u53d7\u6027\u826f\u597d\u3002\u672a\u89c2\u5bdf\u5230\u81f4\u7624\u6027\u6216\u663e\u8457\u7684\u514d\u75ab\u539f\u6027\u53cd\u5e94\u3002\u4e34\u5e8a\u83b7\u76ca\u5305\u62ecUHDRS-TMS\u548cUHDRS-TFC\u8bc4\u5206\u7684\u7a33\u5b9a\u6216\u6539\u5584\uff0c\u652f\u6301\u5f00\u5c55\u66f4\u5927\u89c4\u6a21\u7684\u8bd5\u9a8c\u4ee5\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u5176\u7597\u6548\u548c\u957f\u671f\u83b7\u76ca\u3002<\/span><\/p>\n<blockquote><p>\u53c2\u8003\u8d44\u6599\uff1a[1]:Fernandes, J.M.S., Pagani, E., Wenceslau, C.V.\u00a0<i>et al.<\/i>\u00a0A phase I, open-label study of intravenous human dental pulp stem cells (NestaCell\u00ae) at two dose levels in patients with Huntington\u2019s disease.\u00a0<i>Stem Cell Res Ther<\/i>\u00a0<b>16<\/b>, 611 (2025). https:\/\/doi.org\/10.1186\/s13287-025-04703-w<\/p><\/blockquote>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u8fd1\u671f\uff0c\u56fd\u9645\u671f\u520a\u6742\u5fd7\u300a\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u300b\u53d1\u8868\u4e86\u4e00\u7bc7\u201c\u4e00\u9879\u9488\u5bf9\u4ea8\u5ef7\u987f\u75c5\u60a3\u8005\u91c7\u7528\u4e24\u79cd\u5242\u91cf\u6c34\u5e73\u7684\u9759\u8109\u6ce8\u5c04\u4eba\u7259\u9ad3\u5e72\u7ec6\u80de\uff08 [&hellip;]<\/p>","protected":false},"author":1,"featured_media":20857,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[76,80],"tags":[150,255],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts\/20848"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/comments?post=20848"}],"version-history":[{"count":3,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts\/20848\/revisions"}],"predecessor-version":[{"id":20860,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/posts\/20848\/revisions\/20860"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/media\/20857"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/media?parent=20848"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/categories?post=20848"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/ar\/wp-json\/wp\/v2\/tags?post=20848"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}