{"id":19097,"date":"2025-09-25T03:47:39","date_gmt":"2025-09-24T11:47:39","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/stem-cells\/stem-cell-therapy\/19097.html"},"modified":"2025-10-13T14:59:16","modified_gmt":"2025-10-13T06:59:16","slug":"https-www-hjtdsm-cn-stem-cells-stem-cell-therapy-19097-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19097.html","title":{"rendered":"What practical changes can stem cell therapy bring to tachyphylaxis? Can it improve survival and quality of life?"},"content":{"rendered":"<p>\u6e10\u51bb\u75c7\uff08\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff0cALS\uff09\u662f\u4e00\u79cd\u81f4\u547d\u7684\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\uff0c\u60a3\u8005\u7684\u808c\u8089\u4f1a\u9010\u6e10\u65e0\u529b\u3001\u840e\u7f29\uff0c\u6700\u7ec8\u5f71\u54cd\u547c\u5438\u548c\u541e\u54bd\u529f\u80fd\u3002\u9762\u5bf9\u8fd9\u6837\u4e00\u79cd\u8fdb\u5c55\u8fc5\u901f\u3001\u76ee\u524d\u5c1a\u65e0\u6839\u6cbb\u836f\u7269\u7684\u75be\u75c5\uff0c\u4f60\u662f\u5426\u4e5f\u5728\u60f3\uff1a<strong>\u5e72\u7ec6\u80de\u6cbb\u7597\u771f\u7684\u80fd\u5ef6\u957f\u751f\u5b58\u671f\u5417\uff1f\u5b83\u80fd\u6539\u5584\u60a3\u8005\u7684\u751f\u6d3b\u8d28\u91cf\u5417\uff1f<\/strong><\/p>\n<p>\u8fd1\u5e74\u6765\uff0c<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19199.html\/\" target=\"_blank\" rel=\"noopener\">stem cell therapy<\/a>\u4f5c\u4e3a\u4e00\u79cd\u65b0\u5174\u5e72\u9884\u624b\u6bb5\uff0c\u56e0\u5176\u5728\u5ef6\u7f13\u75c5\u60c5\u8fdb\u5c55\u3001\u4fdd\u62a4\u8fd0\u52a8\u795e\u7ecf\u5143\u548c\u6539\u5584\u751f\u6d3b\u8d28\u91cf\u65b9\u9762\u7684\u6f5c\u5728\u4f5c\u7528\uff0c\u9010\u6e10\u6210\u4e3a\u60a3\u8005\u548c\u5bb6\u5c5e\u5173\u6ce8\u7684\u7126\u70b9\u3002<\/p>\n<p><strong>\u672c\u6587\u5c06\u4ee5\u751f\u5b58\u671f\u548c\u751f\u6d3b\u8d28\u91cf\u4e3a\u6838\u5fc3\uff0c\u5168\u9762\u89e3\u6790\u5e72\u7ec6\u80de\u6cbb\u7597\u5bf9<span class=\"xintheme_tag_link\">tachycardia<\/span>\uff08ALS\uff09\u60a3\u8005\u7684\u5b9e\u9645\u4f5c\u7528<\/strong>\uff0c\u7ed3\u5408\u6700\u65b0\u4e34\u5e8a\u6570\u636e\u548c\u6848\u4f8b\uff0c\u63a2\u8ba8\u5176\u5728\u5ef6\u7f13\u75c5\u7a0b\u3001\u6539\u5584\u8fd0\u52a8\u529f\u80fd\u3001\u547c\u5438\u80fd\u529b\u53ca\u541e\u54bd\u4e0e\u8425\u517b\u72b6\u6001\u7b49\u65b9\u9762\u7684\u6f5c\u5728\u76ca\u5904\u3002<\/p>\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194736-68d3da588146f.png\" alt=\"\" title=\"\"><\/figure>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19097.html\/#%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%83%BD%E4%B8%BA%E6%B8%90%E5%86%BB%E7%97%87%E5%B8%A6%E6%9D%A5%E5%93%AA%E4%BA%9B%E5%AE%9E%E9%99%85%E6%94%B9%E5%8F%98%EF%BC%9F%E8%83%BD%E6%94%B9%E5%96%84%E7%94%9F%E5%AD%98%E6%9C%9F%E4%B8%8E%E7%94%9F%E6%B4%BB%E8%B4%A8%E9%87%8F%E5%90%97%EF%BC%9F\" >What practical changes can stem cell therapy bring to tachyphylaxis? Can it improve survival and quality of life?<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19097.html\/#%E4%B8%80%E3%80%81%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E5%A6%82%E4%BD%95%E5%8F%91%E6%8C%A5%E4%BD%9C%E7%94%A8\" >\u4e00\u3001\u5e72\u7ec6\u80de\u6cbb\u7597\u5982\u4f55\u53d1\u6325\u4f5c\u7528<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19097.html\/#%E4%BA%8C%E3%80%81%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E5%AF%B9%E7%94%9F%E5%AD%98%E6%9C%9F%E7%9A%84%E5%BD%B1%E5%93%8D\" >\u4e8c\u3001\u5e72\u7ec6\u80de\u6cbb\u7597\u5bf9\u751f\u5b58\u671f\u7684\u5f71\u54cd<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19097.html\/#%E4%B8%89%E3%80%81%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E5%AF%B9%E7%94%9F%E6%B4%BB%E8%B4%A8%E9%87%8F%E7%9A%84%E6%94%B9%E5%96%84\" >\u4e09\u3001\u5e72\u7ec6\u80de\u6cbb\u7597\u5bf9\u751f\u6d3b\u8d28\u91cf\u7684\u6539\u5584<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19097.html\/#31_%E5%91%BC%E5%90%B8%E5%8A%9F%E8%83%BD%E6%8F%90%E5%8D%87%E2%80%8B\" >3.1 \u547c\u5438\u529f\u80fd\u63d0\u5347\u200b<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19097.html\/#32_%E8%BF%90%E5%8A%A8%E5%8A%9F%E8%83%BD%E6%94%B9%E5%96%84\" >3.2 \u8fd0\u52a8\u529f\u80fd\u6539\u5584<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19097.html\/#33_%E5%90%9E%E5%92%BD%E4%B8%8E%E8%90%A5%E5%85%BB%E7%8A%B6%E6%80%81%E6%94%B9%E5%96%84%E2%80%8B%E2%80%8B\" >3.3 \u541e\u54bd\u4e0e\u8425\u517b\u72b6\u6001\u6539\u5584\u200b\u200b<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19097.html\/#%E5%9B%9B%E3%80%81%E6%9C%AA%E6%9D%A5%E5%B1%95%E6%9C%9B\" >\u56db\u3001\u672a\u6765\u5c55\u671b<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19097.html\/#%E7%BB%93%E8%AF%AD\" >concluding remarks<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%83%BD%E4%B8%BA%E6%B8%90%E5%86%BB%E7%97%87%E5%B8%A6%E6%9D%A5%E5%93%AA%E4%BA%9B%E5%AE%9E%E9%99%85%E6%94%B9%E5%8F%98%EF%BC%9F%E8%83%BD%E6%94%B9%E5%96%84%E7%94%9F%E5%AD%98%E6%9C%9F%E4%B8%8E%E7%94%9F%E6%B4%BB%E8%B4%A8%E9%87%8F%E5%90%97%EF%BC%9F\"><\/span><strong>What practical changes can stem cell therapy bring to tachyphylaxis? Can it improve survival and quality of life?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<h2><span class=\"ez-toc-section\" id=\"%E4%B8%80%E3%80%81%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E5%A6%82%E4%BD%95%E5%8F%91%E6%8C%A5%E4%BD%9C%E7%94%A8\"><\/span><strong>\u4e00\u3001\u5e72\u7ec6\u80de\u6cbb\u7597\u5982\u4f55\u53d1\u6325\u4f5c\u7528<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5e72\u7ec6\u80de\u6cbb\u7597\u4e3a\u6e10\u51bb\u75c7\u5e26\u6765\u4e86\u65b0\u7684\u601d\u8def\uff0c\u5176\u6f5c\u5728\u7684\u4f5c\u7528\u673a\u5236\u4e3b\u8981\u5305\u62ec\uff1a<\/p>\n<p>\u200b<strong>\u200b\u7ec6\u80de\u66ff\u4ee3\u200b<\/strong>\u200b\uff1a\u5e72\u7ec6\u80de\u80fd\u591f\u200b\u200b\u5206\u5316\u4e3a\u8fd0\u52a8\u795e\u7ecf\u5143\u200b\u200b\uff0c\u66ff\u4ee3\u53d7\u635f\u6216\u6b7b\u4ea1\u7684\u7ec6\u80de\u3002<\/p>\n<p>\u200b<strong>\u200b\u5206\u6ccc\u795e\u7ecf\u8425\u517b\u56e0\u5b50\u200b<\/strong>\u200b\uff1a\u5e72\u7ec6\u80de\u53ef\u4ee5\u5206\u6ccc\u591a\u79cd\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff0c\u200b\u200b\u4fdd\u62a4\u5b58\u6d3b\u7684\u795e\u7ecf\u5143\u200b\u200b\uff0c\u4fc3\u8fdb\u5176\u751f\u5b58\u548c\u529f\u80fd\u6062\u590d\u3002<\/p>\n<p>\u200b<strong>\u200b\u514d\u75ab\u8c03\u8282\u200b<\/strong>\u200b\uff1a\u5e72\u7ec6\u80de\u5177\u6709\u200b\u200b\u8c03\u8282\u514d\u75ab\u7684\u529f\u80fd\u200b\u200b\uff0c\u80fd\u591f\u51cf\u8f7b\u795e\u7ecf\u708e\u75c7\uff0c\u4fdd\u62a4\u795e\u7ecf\u5143\u514d\u53d7\u8fdb\u4e00\u6b65\u635f\u4f24\u3002<\/p>\n<p>\u200b<strong>\u200b\u4fc3\u8fdb\u795e\u7ecf\u518d\u751f\u200b<\/strong>\u200b\uff1a\u5e72\u7ec6\u80de\u53ef\u901a\u8fc7\u5206\u6ccc\u7ec6\u80de\u56e0\u5b50\u548c\u751f\u957f\u56e0\u5b50\uff0c\u200b\u200b\u4fc3\u8fdb\u5468\u56f4\u795e\u7ecf\u7684\u518d\u751f\u4e0e\u4fee\u590d\u3002<\/p>\n<p>\u8fd9\u4e9b\u673a\u5236\u5171\u540c\u4f5c\u7528\uff0c\u4e3a\u53d7\u635f\u7684\u795e\u7ecf\u7cfb\u7edf\u63d0\u4f9b\u4e86\u4fee\u590d\u548c\u4fdd\u62a4\u7684\u53ef\u80fd\u6027\uff0c\u8fd9\u4e5f\u662f<span class=\"xintheme_tag_link\">Stem cell therapy for acromegaly<\/span>\u7684\u7406\u8bba\u57fa\u7840\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%BA%8C%E3%80%81%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E5%AF%B9%E7%94%9F%E5%AD%98%E6%9C%9F%E7%9A%84%E5%BD%B1%E5%93%8D\"><\/span><strong>\u4e8c\u3001\u5e72\u7ec6\u80de\u6cbb\u7597\u5bf9\u751f\u5b58\u671f\u7684\u5f71\u54cd<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5e72\u7ec6\u80de\u6cbb\u7597\u4e3a\u6e10\u51bb\u75c7\u60a3\u8005\u5e26\u6765\u4e86\u751f\u5b58\u671f\u7684\u5b9e\u8d28\u6027\u5ef6\u957f\u3002<\/p>\n<p>\u50cf2025\u5e746\u670816\u65e5\uff0c\u7f8e\u56fd\u751f\u7269\u6280\u672f\u516c\u53f8<a href=\"https:\/\/ir.brainstorm-cell.com\/2025-06-16-BrainStorm-Announces-New-Survival-Data-from-Expanded-Access-Program-Cohort-Remarkably-90-of-ALS-Patients-Survived-Over-5-Years-with-NurOwn-R\" target=\"_blank\" rel=\"nofollow noopener\">BrainStorm Cell Therapeutics, Inc.<\/a>\u516c\u5e03\u4e86\u5176\u81ea\u4f53MSC-NTF\u7ec6\u80de\u4ea7\u54c1<strong>NurOwn\u00ae\u5728\u6269\u5c55\u83b7\u53d6\u8ba1\u5212\uff08EAP\uff09\u4e2d10\u540d\u6e10\u51bb\u75c7\u53d7\u8bd5\u8005\u7684\u66f4\u65b0\u751f\u5b58\u6570\u636e<\/strong>The<sup>[1]<\/sup><\/p>\n<p>\u8be5\u6269\u5c55\u83b7\u53d6\u8ba1\u5212\u7eb3\u5165\u4e8610\u540d\u5df2\u5b8c\u6210\u516c\u53f8III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff08ALS\uff09\u60a3\u8005\uff0c\u65e8\u5728\u4e3a\u8fd9\u4e9b\u60a3\u8005\u5728\u4e34\u5e8a\u7814\u7a76\u4e4b\u5916\u63d0\u4f9b\u7ee7\u7eed\u63a5\u53d7\u6cbb\u7597\u5e76\u6536\u96c6\u957f\u671f\u968f\u8bbf\u4fe1\u606f\u7684\u673a\u4f1a\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194737-68d3da59984b7.png\" alt=\"\" title=\"\"><figcaption><\/figcaption><\/figure>\n<p>\u6b64\u6b21EAP\u8ba1\u5212\u7eb3\u5165\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u663e\u793a\uff1a<\/p>\n<p><strong>\u5e72\u7ec6\u80de\u6cbb\u7597\u540e90%\u7684\u53c2\u4e0e\u8005\uff089\/10\uff09\u5728\u51fa\u73b0ALS\u75c7\u72b6\u540e\u5b58\u6d3b\u8d85\u8fc7\u4e94\u5e74<\/strong>\uff0c\u800c\u73b0\u5728\u5df2\u53d1\u8868\u7684\u4f20\u7edf\u6cbb\u7597\u65b9\u6cd5\u6570\u636e\uff0c\u53ea\u6709\u7ea6\u670910%\u7684ALS\u60a3\u8005\u5b58\u6d3b\u8d85\u8fc7\u4e94\u5e74\u3002<\/p>\n<p><strong>\u8be5\u961f\u5217\u7684\u4e2d\u4f4d\u751f\u5b58\u671f\u4ece\u75c7\u72b6\u51fa\u73b0\u8d77\u8fbe6.8\u5e74\uff08\u8303\u56f46-7\u5e74\uff09\uff0c<\/strong>\u8be5\u961f\u5217\u4e2d\u552f\u4e00\u4e00\u4f8b\u6b7b\u4ea1\u75c5\u4f8b\u53d1\u751f\u5728\u9009\u62e9\u6027\u5b89\u4e50\u6b7b\u4e4b\u540e\u3002<\/p>\n<p>\u82e5\u4ee5\u5df2\u53d1\u8868\u7684\u4f20\u7edf\u6cbb\u7597\u6570\u636e\u4f30\u8ba1\u7ea6 10% \u7684 ALS \u60a3\u8005\u53ef\u5b58\u6d3b\u8d85\u8fc7\u4e94\u5e74\uff0c\u90a3\u4e48\u5728\u72ec\u7acb\u968f\u673a\u62bd\u6837\u7684\u5047\u8bbe\u4e0b\uff0c<strong>\u89c2\u5bdf\u52309\/10\u8fd9\u7c7b\u7ed3\u679c\u7684\u6982\u7387\u975e\u5e38\u6781\u5c0f\u2014\u2014\u7ea6\u4e3a9.1\u00d710\u207b\u2079\uff08\u7ea6 0.00000091%\uff09<\/strong>(math.) genus<strong>\u8fd9\u8bf4\u660e\u5355\u7eaf\u7531\u968f\u673a\u6ce2\u52a8\u5bfc\u81f4\u5982\u6b64\u9ad8\u6bd4\u4f8b\u7684\u53ef\u80fd\u6027\u51e0\u4e4e\u53ef\u4ee5\u5ffd\u7565\u4e0d\u8ba1<\/strong>The<\/p>\n<p>BrainStorm Cell Therapeutics\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98Chaim Lebovits\u8868\u793a\uff1a\u201c\u8fd9\u4e9b\u751f\u5b58\u6570\u636e\u4e3a\u63a5\u53d7NurOwn\u6269\u5927\u53ef\u53ca\u6027\u6cbb\u7597\u7684ALS\u60a3\u8005\u7684\u957f\u671f\u7597\u6548\u63d0\u4f9b\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u771f\u5b9e\u6d1e\u5bdf\u3002<\/p>\n<p><strong>\u603b\u7ed3\u6765\u770b<\/strong>\uff0c\u8fd9\u4e00\u771f\u5b9e\u4e16\u754c\u6570\u636e\u5145\u5206\u8868\u660e\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u6709\u53ef\u80fd\u663e\u8457\u5ef6\u957f\u90e8\u5206\u6e10\u51bb\u75c7\u60a3\u8005\u7684\u751f\u5b58\u671f\uff0c\u4e3a\u4e34\u5e8a\u63d0\u4f9b\u4e86\u65b0\u7684\u5e0c\u671b\uff0c\u4e5f\u4e3a\u672a\u6765\u66f4\u5927\u89c4\u6a21\u7684\u7814\u7a76\u548c\u4e34\u5e8a\u5e94\u7528\u5960\u5b9a\u4e86\u57fa\u7840\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%B8%89%E3%80%81%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E5%AF%B9%E7%94%9F%E6%B4%BB%E8%B4%A8%E9%87%8F%E7%9A%84%E6%94%B9%E5%96%84\"><\/span><strong>\u4e09\u3001\u5e72\u7ec6\u80de\u6cbb\u7597\u5bf9\u751f\u6d3b\u8d28\u91cf\u7684\u6539\u5584<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5e72\u7ec6\u80de\u6cbb\u7597\u5728\u6539\u5584\u6e10\u51bb\u75c7\u60a3\u8005\u751f\u6d3b\u8d28\u91cf\u65b9\u9762\u5c55\u73b0\u51fa\u591a\u65b9\u9762\u7684\u6f5c\u529b\uff0c\u8fd9\u4e9b\u6539\u5584\u5bf9\u60a3\u8005\u7684\u65e5\u5e38\u751f\u6d3b\u610f\u4e49\u91cd\u5927\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"31_%E5%91%BC%E5%90%B8%E5%8A%9F%E8%83%BD%E6%8F%90%E5%8D%87%E2%80%8B\"><\/span><strong>3.1 \u547c\u5438\u529f\u80fd\u63d0\u5347\u200b<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>2025\u5e741\u670829\u65e5\uff0c\u300a<a href=\"https:\/\/www.benthamdirect.com\/content\/journals\/cscr\/10.2174\/011574888X330199250106081717\" target=\"_blank\" rel=\"nofollow noopener\">Current Stem Cell Research &amp; Therapy<\/a>\u300b\u671f\u520a\u5728\u7ebf\u53d1\u8868\u7684\u4e00\u9879\u7814\u7a76\u663e\u793a\uff0c\u91cd\u590d\u8f93\u6ce8\u81ea\u4f53\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08BM-MSCs\uff09\u80fd\u663e\u8457\u6539\u5584ALS\u60a3\u8005\u7684\u7528\u529b\u80ba\u6d3b\u91cf\uff08FVC\uff09\uff0c\u5e76\u4e14\u57283\u4e2a\u6708\u7684\u968f\u8bbf\u671f\u5185\u75c5\u60c5\u4fdd\u6301\u7a33\u5b9a\u3002<sup>[2]<\/sup><\/p>\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194737-68d3da59ac4d8.png\" alt=\"\" title=\"\"><\/figure>\n<p>\u672c\u6b21\u7814\u7a76\u5171\u7eb3\u5165\u4e86<strong>21\u540d<\/strong>ALS\u60a3\u8005\uff086\u540d\u5973\u6027\u548c15\u540d\u7537\u6027\uff09\u53c2\u4e0e\uff0c\u5e73\u5747\u5e74\u9f8452\u5c81\uff0c\u5e73\u5747\u4f53\u91cd64\u516c\u65a4\uff0c\u4ece\u53d1\u75c5\u5f00\u59cb\u5e73\u5747\u60a3\u75c5\u65f6\u95f425\u4e2a\u6708\u3002<\/p>\n<p><strong>safety<\/strong><strong>\u7ed3\u679c\uff1a<\/strong>\u968f\u8bbf\u663e\u793a\uff0c\u91cd\u590d\u79fb\u690dBM-MSCs\u5bf9ALS\u60a3\u8005\u6765\u8bf4\u662f\u5b89\u5168\u7684\uff0c\u672a\u51fa\u73b0\u4e25\u91cd\u4e0d\u826f\u53cd\u5e94\uff0c\u5e38\u89c1\u7684\u526f\u4f5c\u7528\u4e3a\u6682\u65f6\u6027\u53d1\u70e7\u3001\u53d1\u51b7\u548c\u8f7b\u5fae\u5934\u75db\uff0c\u8fd9\u4e9b\u75c7\u72b6\u901a\u8fc7\u8865\u5145\u6cbb\u7597\u53ef\u8fc5\u901f\u7f13\u89e3\u3002<\/p>\n<p><strong>Clinical Outcomes:<\/strong>\u60a3\u8005\u7684FVC\u767e\u5206\u6bd4\u57283\u4e2a\u6708\u5185\u5448\u4e0a\u5347\u8d8b\u52bf\uff0c\u79fb\u690d3\u4e2a\u6708\u65f6\u4e0e\u57fa\u7ebf\u76f8\u6bd4\u6709\u660e\u663e\u5dee\u5f02\uff0c\u8868\u660e<strong>\u5e72\u7ec6\u80de\u79fb\u690d\u80fd\u6539\u5584\u60a3\u8005\u7684\u547c\u5438\u529f\u80fd<\/strong>\uff1bALSFRS\u8bc4\u5206\u57283\u4e2a\u6708\u5185\u4fdd\u6301\u7a33\u5b9a\uff0c\u63d0\u793a<strong>\u5e72\u7ec6\u80de\u79fb\u690d\u80fd\u5ef6\u7f13\u75c5\u60c5\u8fdb\u5c55<\/strong>\u3002\uff08\u56fe1\uff09<\/p>\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194737-68d3da59d63d1.png\" alt=\"\" title=\"\"><figcaption class=\"wp-element-caption\">\u56fe1\uff1aALS\u60a3\u8005ALS-FRS\u8bc4\u5206\u548c%FVC\u53d8\u5316\u7684\u793a\u610f\u56fe\u3002<\/figcaption><\/figure>\n<p><strong>\u5206\u5b50\u68c0\u6d4b\u7ed3\u679c:<\/strong>\u8840\u6e05\u548c\u8111\u810a\u6db2\u4e2d\u7279\u5b9amicroRNA\uff08mir206\u3001mir133a-3p\u548cmir338-3p\uff09\u7684\u8868\u8fbe\u5728\u5e72\u7ec6\u80de\u79fb\u690d\u540e\u867d\u65e0\u663e\u8457\u5dee\u5f02\uff0c\u4f46\u5448\u73b0\u51fa\u4e00\u5b9a\u6539\u5584\u8d8b\u52bf\uff0c\u5982\u8111\u810a\u6db2\u4e2dmir206\u8868\u8fbe\u6301\u7eed\u589e\u52a0\uff0c\u8840\u6e05\u4e2dmir133a-3p\u9010\u6e10\u589e\u52a0\uff0c\u8fd9\u53ef\u80fd\u4e0e\u60a3\u8005\u4e34\u5e8a\u75c7\u72b6\u6539\u5584\u76f8\u5173\u3002<\/p>\n<p>\u8be5\u9879\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u7ed9\u4e88ALS\u60a3\u8005\u591a\u6b21\u9759\u8109\u548c\u9798\u5185\u6ce8\u5c04BM-MSCs\u662f\u4e00\u79cd\u5b89\u5168\u7684\u5e72\u9884\u65b9\u6cd5\uff0c\u6709\u52a9\u4e8e\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\u5e76\u6539\u5584\u4e34\u5e8a\u547c\u5438\u75c7\u72b6\uff0c\u5e76\u4e14\u7279\u5b9amicroRNA\u53d8\u5316\u4e5f\u663e\u793a\u51fa\u6f5c\u5728\u7684\u4e34\u5e8a\u6539\u5584\u8ff9\u8c61\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"32_%E8%BF%90%E5%8A%A8%E5%8A%9F%E8%83%BD%E6%94%B9%E5%96%84\"><\/span><strong>3.2 \u8fd0\u52a8\u529f\u80fd\u6539\u5584<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>2025\u5e743\u670829\u65e5\uff0c\u683c\u9c81\u5409\u4e9a\u7b2c\u6bd4\u5229\u65af\u89e3\u5256\u5b66\u7814\u7a76\u4e0e\u6280\u80fd\u4e2d\u5fc3\u5728\u300aPREMIER JOURNAL OF CASE REPORTS\u300b\u6742\u5fd7\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u540d\u4e3a\u300a\u81ea\u4f53\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff1a\u4e00\u4f8b\u75c5\u4f8b\u62a5\u544a\u300b\u7684\u7814\u7a76\u6210\u679c\u3002<sup>[3]<\/sup><\/p>\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194737-68d3da59e3e04.png\" alt=\"\" title=\"\"><\/figure>\n<p>\u672c\u7814\u7a76\u8bc4\u4f30\u4e86MSC\u79fb\u690d\u5bf9\u4e00\u540d52\u5c81ALS\u60a3\u8005\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7597\u6f5c\u529b\uff0c\u5e76\u8bc4\u4f30\u4e86\u60a3\u8005\u529f\u80fd\u53d8\u5316\u548c\u75c5\u60c5\u8fdb\u5c55\u3002\u60a3\u8005\u63a5\u53d7\u4e86\u4e24\u6b21 MSC\u79fb\u690d\uff0c\u5206\u522b\u901a\u8fc7\u9798\u5185\u548c\u9759\u8109\u7ed9\u836f\u3002\u6cbb\u7597\u540e5\u4e2a\u6708\u5185\u8fdb\u884c\u4e86\u4e34\u5e8a\u8bc4\u4f30\u3001\u808c\u7535\u56fe (EMG) \u548cALS\u529f\u80fd\u8bc4\u5b9a\u91cf\u8868\u4fee\u8ba2\u7248 (ALSFRS-R) \u8bc4\u4f30\u3002<\/p>\n<p>\u79fb\u690d\u540e\u4e00\u4e2a\u6708\uff0c<strong>\u60a3\u8005\u5728\u8fd0\u52a8\u529f\u80fd\u65b9\u9762\u663e\u793a\u51fa\u663e\u8457\u6539\u5584<\/strong>(math.) genus<strong>\u5305\u62ec\u80fd\u591f\u5c06\u817f\u90e8\u62ac\u8d77\u81f3\u5e8a\u976210\u81f320\u5ea6\u7684\u89d2\u5ea6\uff0c\u5e76\u80fd\u72ec\u7acb\u5730\u8de8\u8fc7\u80eb\u9aa8<\/strong>\u3002\u5230\u7b2c\u4e8c\u4e2a\u6708\u65f6\uff0c\u8fd9\u4e00\u8fdb\u6b65\u66f4\u4e3a\u663e\u8457\uff0c\u5979\u62ac\u8d77\u7684\u817f\u90e8\u89d2\u5ea6\u8fbe\u5230\u4e8620\u81f330\u5ea6\uff0c\u4e0b\u80a2\u529b\u91cf\u7684\u589e\u5f3a\u4f34\u968f\u7740\u5ef6\u9ad3\u529f\u80fd\u7684\u6539\u5584\u3002<\/p>\n<p>\u6b64\u5916<strong>\u8a00\u8bed\u6e05\u6670\u5ea6\u4ee5\u53ca\u541e\u54bd\u529f\u80fd\u4e5f\u5f97\u5230\u4e86\u6539\u5584<\/strong>\uff0c\u8fd9\u53cd\u6620\u5728ALSFRS-R\u8bc4\u5206\u4e0a\uff0c\u5e76\u4e14\u5979\u4e0d\u518d\u9700\u8981\u5438\u75f0\u3001\u975e\u4fb5\u5165\u6027\u6b63\u538b\u901a\u6c14(NIPPV)\u6216\u5176\u4ed6\u5f62\u5f0f\u7684\u6c27\u6c14\u652f\u6301\u3002\u8fd9\u4e9b\u53d1\u73b0\u7a81\u663e\u4e86\u5e72\u7ec6\u80de\u79fb\u690d\u5728\u89e3\u51b3ALS\u60a3\u8005\u7684\u8fd0\u52a8\u75c7\u72b6\u548c\u5ef6\u9ad3\u75c7\u72b6\u65b9\u9762\u7684\u6f5c\u529b\u3002<\/p>\n<p><strong>\u603b\u7ed3\u6765\u770b<\/strong>\uff0c\u8fd9\u4e00\u6848\u4f8b\u663e\u793a\uff0c\u5e72\u7ec6\u80de\u79fb\u690d\u4e0d\u4ec5\u5728\u6539\u5584ALS\u60a3\u8005\u7684\u8fd0\u52a8\u80fd\u529b\u65b9\u9762\u5177\u6709\u663e\u8457\u6f5c\u529b\uff0c\u4e5f\u80fd\u7f13\u89e3\u5ef6\u9ad3\u76f8\u5173\u75c7\u72b6\uff0c\u5982\u541e\u54bd\u548c\u547c\u5438\u529f\u80fd\u969c\u788d\uff0c\u4e3a\u5e72\u7ec6\u80de\u5728\u4e34\u5e8a\u6cbb\u7597ALS\u4e2d\u7684\u5e94\u7528\u63d0\u4f9b\u4e86\u79ef\u6781\u7684\u4e34\u5e8a\u8bc1\u636e\u3002<\/p>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"33_%E5%90%9E%E5%92%BD%E4%B8%8E%E8%90%A5%E5%85%BB%E7%8A%B6%E6%80%81%E6%94%B9%E5%96%84%E2%80%8B%E2%80%8B\"><\/span><strong>3.3 \u541e\u54bd\u4e0e\u8425\u517b\u72b6\u6001\u6539\u5584\u200b\u200b<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>2025\u5e748\u670829\u65e5\uff0c\u4f0a\u6717\u5fb7\u9ed1\u5170\u5e72\u7ec6\u80de\u7814\u7a76\u6240\u5728\u300aNeurodegenerative Disease Management\u300b\u671f\u520a\u6742\u5fd7\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u540d\u4e3a\u300a\u7b26\u5408GMP\/GCP\u6807\u51c6\u7684\u540c\u79cd\u5f02\u4f53\u534e\u901a\u80f6\u95f4\u5145\u8d28\u57fa\u8d28\u7ec6\u80de\u5728ALS\u60a3\u8005\u4e2d\u7684\u9759\u8109\u5185\u4e0e\u9798\u5185\u79fb\u690d\uff1a\u4e00\u9879I\u671f\u7814\u7a76\u300b\u7684\u7814\u7a76\u6210\u679c\u3002<sup>[4]<\/sup><\/p>\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924194737-68d3da59ef1b6.png\" alt=\"\" title=\"\"><\/figure>\n<p>\u7814\u7a76\u4eba\u5458\u5f00\u5c55\u4e86\u4e00\u9879\u521b\u65b0\u6027I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u6bd4\u8f83\u9759\u8109\u4e0e\u9798\u5185\u79fb\u690d60\u767e\u4e07\u5355\u4f4dGMP\u5408\u89c4\u8110\u5e26\u534e\u901a\u80f6\u95f4\u5145\u8d28\u5e72\u7ec6\u80de(WJ-MSCs)\u7684\u5b89\u5168\u6027\u548c\u521d\u6b65\u7597\u6548\u3002<\/p>\n<p>\u7ed3\u679c\u663e\u793a\uff0c<strong>\u60a3\u8005\u5728\u553e\u6db2\u5206\u6ccc\u3001\u541e\u54bd\u548c\u8a00\u8bed\u80fd\u529b\u7b49\u65b9\u9762\u5747\u6709\u6539\u5584\uff0c\u540c\u65f6\u89c2\u5bdf\u5230\u808c\u8089\u9707\u98a4\u548c\u808c\u675f\u98a4\u52a8\u51cf\u5c11\uff0c\u808c\u529b\u589e\u5f3a<\/strong>\u3002\u5b89\u5168\u6027\u65b9\u9762\uff0c\u6574\u4e2a\u7814\u7a76\u8fc7\u7a0b\u4e2d\u672a\u62a5\u544a\u4e0e\u5e72\u9884\u6216\u7ec6\u80de\u6ce8\u5c04\u76f8\u5173\u7684\u4e0d\u826f\u4e8b\u4ef6\u3002<\/p>\n<p><strong>\u603b\u7ed3\u6765\u770b<\/strong>\uff0c\u8fd9\u4e00\u7814\u7a76\u63d0\u793a\u5e72\u7ec6\u80de\u6cbb\u7597\u4e0d\u4ec5\u53ef\u80fd\u6539\u5584ALS\u60a3\u8005\u7684\u541e\u54bd\u548c\u8425\u517b\u72b6\u6001\uff0c\u8fd8\u80fd\u589e\u5f3a\u808c\u529b\u5e76\u7f13\u89e3\u808c\u675f\u98a4\u52a8\uff0c\u521d\u6b65\u663e\u793a\u51fa\u8f83\u597d\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\uff0c\u4e3a\u672a\u6765\u8fdb\u4e00\u6b65\u4e34\u5e8a\u9a8c\u8bc1\u63d0\u4f9b\u4e86\u79ef\u6781\u4f9d\u636e\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E5%9B%9B%E3%80%81%E6%9C%AA%E6%9D%A5%E5%B1%95%E6%9C%9B\"><\/span><strong>\u56db\u3001\u672a\u6765\u5c55\u671b<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5c3d\u7ba1\u76ee\u524d\u5e72\u7ec6\u80de\u6cbb\u7597\u5728\u6e10\u51bb\u75c7\uff08ALS\uff09\u4e2d\u7684\u5e94\u7528\u4ecd\u5904\u4e8e\u4e34\u5e8a\u7814\u7a76\u9636\u6bb5\uff0c\u4f46\u5df2\u6709\u7684\u751f\u5b58\u671f\u5ef6\u957f\u548c\u751f\u6d3b\u8d28\u91cf\u6539\u5584\u7684\u6570\u636e\u4e3a\u672a\u6765\u53d1\u5c55\u63d0\u4f9b\u4e86\u575a\u5b9e\u7684\u57fa\u7840\u3002\u968f\u7740\u5e72\u7ec6\u80de\u6280\u672f\u7684\u4e0d\u65ad\u4f18\u5316\uff0c\u5305\u62eciPSC\u4e0e\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u5e94\u7528\u3001\u5b9a\u5411\u5206\u5316\u65b9\u6848\u7684\u6539\u8fdb\u4ee5\u53ca\u5b89\u5168\u6027\u4e0e\u514d\u75ab\u6392\u65a5\u95ee\u9898\u7684\u89e3\u51b3\uff0c\u672a\u6765\u6709\u671b\u5b9e\u73b0\u66f4\u7cbe\u51c6\u3001\u66f4\u6301\u4e45\u7684\u7597\u6548\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u5e72\u7ec6\u80de\u4e0e\u57fa\u56e0\u6cbb\u7597\u3001\u836f\u7269\u8054\u5408\u5e72\u9884\u7b49\u591a\u6a21\u5f0f\u6cbb\u7597\u7684\u63a2\u7d22\uff0c\u4e5f\u53ef\u80fd\u4e3aALS\u60a3\u8005\u5e26\u6765\u66f4\u5168\u9762\u7684\u795e\u7ecf\u4fdd\u62a4\u548c\u529f\u80fd\u6539\u5584\u3002\u957f\u671f\u968f\u8bbf\u548c\u5927\u89c4\u6a21\u3001\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\u5c06\u662f\u9a8c\u8bc1\u7597\u6548\u548c\u5b89\u5168\u6027\u7684\u5173\u952e\u3002<\/p>\n<p>\u603b\u7684\u6765\u8bf4\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u4e3aALS\u5e26\u6765\u4e86\u65b0\u7684\u5e0c\u671b\uff0c\u4e0d\u4ec5\u4e3a\u5ef6\u957f\u751f\u5b58\u671f\u63d0\u4f9b\u53ef\u80fd\uff0c\u4e5f\u4e3a\u6539\u5584\u8fd0\u52a8\u529f\u80fd\u3001\u547c\u5438\u3001\u541e\u54bd\u53ca\u5fc3\u7406\u72b6\u6001\u6253\u5f00\u4e86\u65b0\u7684\u7a7a\u95f4\u3002\u968f\u7740\u79d1\u5b66\u7814\u7a76\u7684\u63a8\u8fdb\uff0c\u6211\u4eec\u6709\u7406\u7531\u671f\u5f85\u672a\u6765\u80fd\u51fa\u73b0\u66f4\u6709\u6548\u3001\u66f4\u5b89\u5168\u3001\u53ef\u53ca\u6027\u66f4\u9ad8\u7684\u5e72\u7ec6\u80de\u7597\u6cd5\uff0c\u4e3a\u6e10\u51bb\u75c7\u60a3\u8005\u53ca\u5176\u5bb6\u5ead\u5e26\u6765\u5207\u5b9e\u7684\u6539\u53d8\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E7%BB%93%E8%AF%AD\"><\/span><strong>concluding remarks<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u603b\u800c\u8a00\u4e4b\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u4e3a\u6e10\u51bb\u75c7\u60a3\u8005\u5e26\u6765\u4e86\u65b0\u7684\u5e0c\u671b\uff0c\u5728\u200b<strong>\u200b\u5ef6\u957f\u751f\u5b58\u671f\u200b<\/strong>\u200b\u548c\u200b<strong>\u200b\u6539\u5584\u751f\u6d3b\u8d28\u91cf\u200b<\/strong>\u200b\u65b9\u9762\u90fd\u5c55\u73b0\u51fa\u6f5c\u5728\u7684\u5b9e\u9645\u4ef7\u503c\u3002\u5b83\u53ef\u80fd\u901a\u8fc7\u591a\u79cd\u673a\u5236\u53d1\u6325\u4f5c\u7528\uff0c\u5e76\u4e14\u5df2\u6709\u4e34\u5e8a\u6570\u636e\u548c\u771f\u5b9e\u6848\u4f8b\u652f\u6301\u5176\u79ef\u6781\u6548\u679c\u3002<\/p>\n<p>\u7136\u800c\uff0c\u4e5f\u5fc5\u987b\u6e05\u9192\u8ba4\u8bc6\u5230\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u76ee\u524d\u200b\u200b\u4ecd\u662f\u4e00\u79cd\u5904\u4e8e\u7814\u7a76\u9636\u6bb5\u7684\u65b9\u6cd5\u200b\u200b\uff0c\u5e76\u975e\u201c\u5947\u8ff9\u7597\u6cd5\u201d\u3002\u5bf9\u5176\u6548\u679c\u9700\u8981\u7406\u6027\u671f\u5f85\uff0c\u5bf9\u4e8e\u60a3\u8005\u548c\u5bb6\u5c5e\u6765\u8bf4\uff0c\u200b\u200b\u5728\u8003\u8651\u4efb\u4f55\u6cbb\u7597\u9009\u62e9\u524d\uff0c\u52a1\u5fc5\u54a8\u8be2\u4e13\u4e1a\u7684\u795e\u7ecf\u79d1\u533b\u751f\uff0c\u901a\u8fc7\u6b63\u89c4\u6e20\u9053\u4e86\u89e3\u6700\u65b0\u7684\u3001\u7ecf\u8fc7\u79d1\u5b66\u9a8c\u8bc1\u7684\u6cbb\u7597\u4fe1\u606f\u200b\u200b\uff0c\u5e76\u8b66\u60d5\u90a3\u4e9b\u5938\u5927\u5176\u8bcd\u3001\u672a\u7ecf\u8bc1\u5b9e\u7684\u5ba3\u4f20\u3002\u79d1\u5b66\u7684\u8fdb\u6b65\u9700\u8981\u65f6\u95f4\uff0c\u4f46\u6211\u4eec\u6709\u7406\u7531\u671f\u5f85\u672a\u6765\u80fd\u6709\u66f4\u591a\u6709\u6548\u7684\u65b9\u6cd5\u6765\u201c\u89e3\u51bb\u201d\u751f\u547d\u3002<\/p>\n<blockquote><p>References:<\/p>\n<p>[1]https:\/\/ir.brainstorm-cell.com\/2025-06-16-BrainStorm-Announces-New-Survival-Data-from-Expanded-Access-Program-Cohort-Remarkably-90-of-ALS-Patients-Survived-Over-5-Years-with-NurOwn-R<\/p>\n<p>[2]Zahraa Alkhazaali-Ali et al.Evaluation of Safety and Efficacy of Repeated Mesenchymal Stem Cell Transplantation in Patients with Amyotrophic Lateral Sclerosis (ALS) by Investigating Patient\u2019s Specific microRNAs as Novel Biomarkers: A Clinical Trial Study.DOI: 10.2174\/011574888X330199250106081717.<\/p>\n<p>[3]https:\/\/premierscience.com\/wp-content\/uploads\/2025\/04\/pjcr-25-812-1.pdf<\/p>\n<p>[4]Karimi S, Ghaheri A, Madani H, Beheshti Maal A, Sadri B, Khodadoust E, Sharafi F, Vosough M, Nabavi SM. Intravenous vs intrathecal transplantation of allogeneic GMP\/GCP compliant Wharton&#8217;s jelly mesenchymal stromal cells in ALS patients: a phase I study. Neurodegener Dis Manag. 2025 Aug 29:1-9. doi: 10.1080\/17582024.2025.2553499. Epub ahead of print. PMID: 40879603.<\/p>\n<p>Disclaimer: This article is intended only to disseminate scientific knowledge and share industry perspectives, and does not constitute any clinical diagnostic advice! The information published by Hangi Stem Cells is not a substitute for the professional advice of a physician or pharmacist. 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