{"id":19258,"date":"2025-09-25T04:17:42","date_gmt":"2025-09-24T12:17:42","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/stem-cells\/nsc\/19258.html"},"modified":"2025-10-10T15:30:42","modified_gmt":"2025-10-10T07:30:42","slug":"https-www-hjtdsm-cn-stem-cells-nsc-19258-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html","title":{"rendered":"Neural stem cell transplantation for neurodegenerative diseases: from mechanisms of adult nerve regeneration to the potential for clinical translation"},"content":{"rendered":"<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u591a\u5e74\u6765\uff0c\u5229\u7528\u5e72\u7ec6\u80de\u7597\u6cd5\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u7406\u5ff5\u53d1\u751f\u4e86\u91cd\u5927\u53d8\u5316\uff0c\u5e76\u5728\u6700\u8fd1\u53d6\u5f97\u4e86\u91cd\u5927\u8fdb\u5c55\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u795e\u7ecf\u8425\u517b\u56e0\u5b50\u3001\u751f\u957f\u56e0\u5b50\u548c\u8f6c\u5f55\u56e0\u5b50\u5171\u540c\u8c03\u63a7<span class=\"xintheme_tag_link\">neural stem cell<\/span>\u7684\u589e\u6b96\u4e0e\u5206\u5316\uff0c\u5176\u8c03\u8282\u673a\u5236\uff08\u5305\u62ec\u8d1f\u53cd\u9988\uff09\u7684\u7834\u574f\u53ef\u80fd\u5f15\u53d1\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u3002\u5f53\u524d\u5168\u7403\u65e5\u76ca\u5173\u6ce8\u6b64\u7c7b\u75be\u75c5\uff0c\u5176\u75c5\u7406\u6838\u5fc3\u5728\u4e8e\u795e\u7ecf\u5143\u6b7b\u4ea1\u3001\u8f74\u7a81\u518d\u751f\u5931\u8d25\u53ca\u795e\u7ecf\u5143\u7ed3\u6784\u635f\u4f24\u3002\u73b0\u6709\u836f\u7269\u4ec5\u80fd\u7f13\u89e3\u75c7\u72b6\uff0c\u65e0\u6cd5\u963b\u65ad\u75be\u75c5\u8fdb\u5c55\u3002\u56e0\u6b64\uff0c\u7814\u7a76\u4eba\u5458\u6b63\u5728\u7814\u7a76\u521b\u65b0\u7684\u6cbb\u7597\u7b56\u7565\uff0c\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u6b63\u6210\u4e3a\u4e00\u79cd\u6709\u5e0c\u671b\u7684\u9014\u5f84\u3002<\/p><\/blockquote>\n<p>\u8fd1\u65e5\uff0c\u56fd\u9645\u671f\u520a\u6742\u5fd7\u300a<a href=\"https:\/\/www.frontiersin.org\/journals\/molecular-medicine\/articles\/10.3389\/fmmed.2025.1569717\/full\" target=\"_blank\" rel=\"nofollow noopener\">Frontiers in Molecular Medicine<\/a>\u300b\u53d1\u8868\u4e86\u4e00\u9879\u201c\u6210\u4eba\u795e\u7ecf\u518d\u751f\u4e2d\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\u53ca\u5176\u5728\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u4e2d\u7684\u6cbb\u7597\u5e94\u7528\uff1a\u7b80\u660e\u7efc\u8ff0\u201c\u7684\u7814\u7a76<sup>[1]<\/sup>The<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201741-68d3e1650eab0.jpg\" alt=\"\" title=\"\"><figcaption><\/figcaption><\/figure>\n<p>\u8be5\u7814\u7a76\u7efc\u8ff0\u8868\u660e\uff1a<strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u6cbb\u7597\u5e94\u7528\u5bf9\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff08\u5305\u62ec\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3001\u4e2d\u98ce\u3001\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\u3001\u810a\u9ad3\u635f\u4f24\u548c\u591a\u53d1\u6027\u786c\u5316\u75c7\uff09\u5177\u6709\u91cd\u8981\u524d\u666f\u3002\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u65e8\u5728\u8865\u5145\u4e22\u5931\u7684\u795e\u7ecf\u5143\uff0c\u5e76\u4fc3\u8fdb\u8fd9\u4e9b\u75be\u75c5\u4e2d\u7684\u795e\u7ecf\u518d\u751f<\/strong>The<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 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href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#%E6%88%90%E4%BA%BA%E6%B5%B7%E9%A9%AC%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F%E7%9A%84%E5%8A%9F%E8%83%BD%E7%89%B9%E6%80%A7%E4%B8%8E%E4%B8%B4%E5%BA%8A%E6%84%8F%E4%B9%89\" >\u6210\u4eba\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f\u7684\u529f\u80fd\u7279\u6027\u4e0e\u4e34\u5e8a\u610f\u4e49<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#%E5%85%B6%E4%BB%96%E5%A4%A7%E8%84%91%E5%8C%BA%E5%9F%9F%E7%9A%84%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F\" >\u5176\u4ed6\u5927\u8111\u533a\u57df\u7684\u6210\u4eba\u795e\u7ecf\u53d1\u751f<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#%E6%A3%80%E6%B5%8B%E7%A5%9E%E7%BB%8F%E5%86%8D%E7%94%9F%E7%BB%86%E8%83%9E%E7%B1%BB%E5%9E%8B%E7%9A%84%E5%88%86%E5%AD%90%E6%A0%87%E5%BF%97%E7%89%A9%E6%9C%89%E5%93%AA%E4%BA%9B%EF%BC%9F\" >\u68c0\u6d4b\u795e\u7ecf\u518d\u751f\u7ec6\u80de\u7c7b\u578b\u7684\u5206\u5b50\u6807\u5fd7\u7269\u6709\u54ea\u4e9b\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#%E4%BB%80%E4%B9%88%E6%98%AF%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%86%8D%E7%94%9F%E7%9A%84%E8%B0%83%E6%8E%A7%E6%9C%BA%E5%88%B6%EF%BC%9F\" >\u4ec0\u4e48\u662f\u6210\u4eba\u795e\u7ecf\u518d\u751f\u7684\u8c03\u63a7\u673a\u5236\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E6%B2%BB%E7%96%97%E5%BA%94%E7%94%A8%E5%8F%8A%E6%A0%B8%E5%BF%83%E6%9C%BA%E5%88%B6\" >\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u6cbb\u7597\u5e94\u7528\u53ca\u6838\u5fc3\u673a\u5236<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%BD%AC%E5%8C%96%E7%AD%96%E7%95%A5%E4%B8%8E%E7%A7%91%E5%AD%A6%E5%9F%BA%E7%A1%80\" >\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u4e34\u5e8a\u8f6c\u5316\u7b56\u7565\u4e0e\u79d1\u5b66\u57fa\u7840<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E7%A5%9E%E7%BB%8F%E9%80%80%E8%A1%8C%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E5%BA%94%E7%94%A8%E6%9C%89%E5%93%AA%E4%BA%9B%EF%BC%9F\" >\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u5e94\u7528\u6709\u54ea\u4e9b\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E7%9A%84%E6%9C%80%E6%96%B0%E8%BF%9B%E5%B1%95%E5%92%8C%E6%96%B0%E8%A7%81%E8%A7%A3\" >\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u7684\u6700\u65b0\u8fdb\u5c55\u548c\u65b0\u89c1\u89e3<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link 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href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#3%E3%80%81%E6%8A%80%E6%9C%AF%E8%9E%8D%E5%90%88%E9%A9%B1%E5%8A%A8%E7%B2%BE%E5%87%86%E6%B2%BB%E7%96%97%EF%BC%9A%E5%9F%BA%E5%9B%A0%E5%B7%A5%E7%A8%8B%E4%B8%8E%E6%88%90%E5%83%8F%E6%8A%80%E6%9C%AF%E8%B5%8B%E8%83%BD%E6%B2%BB%E7%96%97%E5%8D%87%E7%BA%A7\" >3\u3001\u6280\u672f\u878d\u5408\u9a71\u52a8\u7cbe\u51c6\u6cbb\u7597\uff1a\u57fa\u56e0\u5de5\u7a0b\u4e0e\u6210\u50cf\u6280\u672f\u8d4b\u80fd\u6cbb\u7597\u5347\u7ea7<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E7%A5%9E%E7%BB%8F%E9%80%80%E8%A1%8C%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E5%89%8D%E6%99%AF%E5%92%8C%E6%9C%AA%E6%9D%A5%E6%96%B9%E5%90%91\" 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class=\"ez-toc-link ez-toc-heading-28\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/nsc\/19258.html\/#4_%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E9%A2%A0%E8%A6%86%E6%80%A7%E6%8A%80%E6%9C%AF%E8%9E%8D%E5%90%88%E8%B7%AF%E5%BE%84\" >4. \u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u98a0\u8986\u6027\u6280\u672f\u878d\u5408\u8def\u5f84<\/a><\/li><\/ul><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h1 id=\"h-\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5-\u4ece\u53d1\u73b0\u6210\u4eba\u795e\u7ecf\u518d\u751f\u7684\u673a\u5236\u5230\u4e34\u5e8a\u8f6c\u5316\u6f5c\u529b\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E7%A5%9E%E7%BB%8F%E9%80%80%E8%A1%8C%E6%80%A7%E7%96%BE%E7%97%85%EF%BC%9A%E4%BB%8E%E5%8F%91%E7%8E%B0%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%86%8D%E7%94%9F%E7%9A%84%E6%9C%BA%E5%88%B6%E5%88%B0%E4%B8%B4%E5%BA%8A%E8%BD%AC%E5%8C%96%E6%BD%9C%E5%8A%9B\"><\/span><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff1a\u4ece\u53d1\u73b0\u6210\u4eba\u795e\u7ecf\u518d\u751f\u7684\u673a\u5236\u5230\u4e34\u5e8a\u8f6c\u5316\u6f5c\u529b<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p><strong>\u7814\u7a76\u76ee\u6807\u4e0e\u6cbb\u7597\u524d\u666f\uff1a<\/strong>\u76ee\u524d\uff0c\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u8bc1\u660e\u5176\u5728\u6539\u5584\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u60a3\u8005\u7684\u8ba4\u77e5\u548c\u8fd0\u52a8\u529f\u80fd\u65b9\u9762\u53d6\u5f97\u4e86\u4e00\u5b9a\u6210\u6548\uff0c\u4f46\u7531\u4e8e<strong>\u514d\u75ab\u6392\u65a5\u3001\u7ec6\u80de\u6765\u6e90\u7684\u8bc6\u522b\u3001\u4f26\u7406\u95ee\u9898\u3001\u7597\u6548\u4ee5\u53ca\u6f5c\u5728\u7684\u526f\u4f5c\u7528<\/strong>\u7b49\u6311\u6218\uff0c\u5728\u5927\u89c4\u6a21\u4e34\u5e8a\u5e94\u7528\u4e4b\u524d\uff0c\u5fc5\u987b\u8fdb\u884c\u5f7b\u5e95\u7684\u8c03\u67e5\u7814\u7a76\u3002<\/p>\n<p>\u5c3d\u7ba1\u5b58\u5728\u8fd9\u4e9b\u6311\u6218\uff0c\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u4ecd\u5177\u6709\u5de8\u5927\u7684\u6f5c\u529b\uff0c\u6709\u671b\u5f7b\u5e95\u6539\u53d8\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u548c\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u635f\u4f24\u7684\u6cbb\u7597\u65b9\u5f0f\u3002\u56e0\u6b64\uff0c<strong>\u672c\u6587\u7684\u6838\u5fc3\u76ee\u6807\u5373\u5728\u4e8e\u6982\u8ff0\u6210\u4f53\u795e\u7ecf\u53d1\u751f\u7684\u673a\u5236\uff0c\u5e76\u91cd\u70b9\u63a2\u8ba8\u795e\u7ecf\u5e72\u7ec6\u80de\u5728\u6cbb\u7597\u591a\u79cd\u795e\u7ecf\u7cfb\u7edf\u5f02\u5e38\u65b9\u9762\u7684\u5de8\u5927\u6cbb\u7597\u6f5c\u529b\u548c\u5e94\u7528\u524d\u666f\u3002<\/strong><\/p>\n<h2 id=\"h-\u5168\u7403\u8111\u90e8\u75be\u75c5\u6311\u6218\u4e0e\u73b0\u72b6\"><span class=\"ez-toc-section\" id=\"%E5%85%A8%E7%90%83%E8%84%91%E9%83%A8%E7%96%BE%E7%97%85%E6%8C%91%E6%88%98%E4%B8%8E%E7%8E%B0%E7%8A%B6\"><\/span><strong>\u5168\u7403\u8111\u90e8\u75be\u75c5\u6311\u6218\u4e0e\u73b0\u72b6<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5f53\u524d\uff0c\u5168\u7403\u5bf9\u5f71\u54cd\u4eba\u7c7b\u548c\u52a8\u7269\u7684\u5404\u7c7b\u8111\u90e8\u75be\u75c5\uff08\u5305\u62ec\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u3001\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u8111\u635f\u4f24\u53ca\u7279\u53d1\u6027\u75be\u75c5\uff09\u65e5\u76ca\u5173\u6ce8\uff0c\u8fd9\u4e9b\u75be\u75c5\u5bf9\u5927\u91cf\u4eba\u7fa4\u9020\u6210\u4e86\u4e25\u91cd\u8d1f\u62c5\u3002<\/p>\n<p>\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u7684\u635f\u4f24\u6e90\u4e8e<strong>\u7ec6\u80de\u6b7b\u4ea1\u3001\u8f74\u7a81\u518d\u751f\u5931\u8d25\u3001\u8131\u9ad3\u9798\u53ca\u795e\u7ecf\u5143\u7ed3\u6784\u4e0e\u529f\u80fd\u53d7\u635f<\/strong>\u7b49\u591a\u79cd\u539f\u56e0\uff0c\u7edf\u79f0\u4e3a\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u3002\u7136\u800c\uff0c\u73b0\u6709\u83b7\u6279\u836f\u7269\u4ec5\u80fd\u7f13\u89e3\u75c7\u72b6\uff0c\u7f3a\u4e4f\u80fd\u6539\u53d8\u75be\u75c5\u8fdb\u7a0b\u7684\u6709\u6548\u7597\u6cd5\u3002<\/p>\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201741-68d3e165367b8.jpg\" width=\"690\" height=\"388\" alt=\"\" title=\"\"><\/figure>\n<h2 id=\"h-\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u7597\u6cd5\u7684\u5174\u8d77\u4e0e\u7ec6\u80de\u6765\u6e90\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E7%96%97%E6%B3%95%E7%9A%84%E5%85%B4%E8%B5%B7%E4%B8%8E%E7%BB%86%E8%83%9E%E6%9D%A5%E6%BA%90\"><\/span><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u7597\u6cd5\u7684\u5174\u8d77\u4e0e\u7ec6\u80de\u6765\u6e90<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u4e3a\u5e94\u5bf9\u6311\u6218\uff0c\u7814\u7a76\u8005\u6b63\u79ef\u6781\u63a2\u7d22\u521b\u65b0\u7597\u6cd5\uff0c\u5728\u4f17\u591a\u6cbb\u7597\u7b56\u7565\u4e2d\uff0c\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u8131\u9896\u800c\u51fa\uff0c\u6210\u4e3a\u6cbb\u7597\u8111\u90e8\u75be\u75c5\u7684\u4e00\u79cd\u975e\u5e38\u6709\u5e0c\u671b\u7684\u9009\u62e9\u3002<strong>\u5e38\u7528\u7684\u8111\u90e8\u75be\u75c5\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u5305\u62ec\u6210\u4f53\u795e\u7ecf\u5e72\u7ec6\u80de (NSC)\u3001\u80da\u80ce\u795e\u7ecf\u5e72\u7ec6\u80de\u548c\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de<\/strong>The<\/p>\n<p>\u5e72\u7ec6\u80de\u5177\u6709\u81ea\u6211\u66f4\u65b0\u548c\u5206\u5316\u6210\u591a\u79cd\u7ec6\u80de\u7c7b\u578b\u7684\u80fd\u529b\uff0c\u6309\u6765\u6e90\u53ef\u5206\u4e3a\u80da\u80ce\u4e0e\u6210\u4f53\u5e72\u7ec6\u80de\uff0c\u6309\u5206\u5316\u6f5c\u80fd\u5219\u5206\u4e3a\u5168\u80fd\u6027\u3001\u591a\u80fd\u6027\u3001\u591a\u6f5c\u80fd\u6027\u548c\u5355\u80fd\u6027\u3002<\/p>\n<p>\u4f46\u80da\u80ce\u5e72\u7ec6\u80de\u5e94\u7528\u53d7\u9650\u4e8e\u4f26\u7406\u3001\u53ef\u7528\u6027\u548c\u514d\u75ab\u6392\u65a5\u95ee\u9898\uff0c\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u7597\u6cd5\u4e5f\u9762\u4e34\u83b7\u53d6\u56f0\u96be\u3001\u6210\u672c\u9ad8\u548c\u6280\u672f\u9650\u5236\u3002<\/p>\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201741-68d3e16541a44.jpg\" width=\"698\" height=\"388\" alt=\"\" title=\"\"><\/figure>\n<h3 id=\"h-\u6210\u4f53\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u4f18\u52bf\u4e0e\u6cbb\u7597\u673a\u5236\"><span class=\"ez-toc-section\" id=\"%E6%88%90%E4%BD%93%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E4%BC%98%E5%8A%BF%E4%B8%8E%E6%B2%BB%E7%96%97%E6%9C%BA%E5%88%B6\"><\/span><strong>\u6210\u4f53\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u4f18\u52bf\u4e0e\u6cbb\u7597\u673a\u5236<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u6210\u4f53\u795e\u7ecf\u5e72\u7ec6\u80de\u56e0\u5176\u80fd\u751f\u6210\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u591a\u79cd\u7ec6\u80de\u7c7b\u578b\uff0c\u6210\u4e3a\u6cbb\u7597\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u7684\u7406\u60f3\u9009\u62e9\u3002\u5b83\u4eec\u5b58\u5728\u4e8e\u6210\u4f53\u7279\u5b9a\u8111\u533a\uff08\u5982\u8111\u5ba4\u4e0b\u533a\u3001\u6d77\u9a6c\u9f7f\u72b6\u56de\u7b49\uff09\uff0c\u53ef\u88ab\u5206\u79bb\u57f9\u517b\u7528\u4e8e\u7ec6\u80de\u66ff\u4ee3\u6cbb\u7597\u3002<strong>\u76f8\u8f83\u4e8e\u5176\u4ed6\u6765\u6e90\uff0c\u5176\u4f18\u52bf\u5728\u4e8e\u907f\u514d\u4e86\u4f26\u7406\u4e89\u8bae\u3002<\/strong><\/p>\n<p><strong>\u6210\u4f53\u795e\u7ecf\u5e72\u7ec6\u80de\u4e0d\u4ec5\u901a\u8fc7\u8865\u5145\u7ec6\u80de\u53d1\u6325\u7a33\u6001\u4fee\u590d\u4f5c\u7528\uff0c\u8fd8\u80fd\u901a\u8fc7\u4ea7\u751f\u5177\u6709\u65b0\u7279\u6027\u7684\u795e\u7ecf\u5143\uff08\u5982\u8d85\u5174\u594b\u6027\uff09\u548c\u5efa\u7acb\u65b0\u7a81\u89e6\u8fde\u63a5\uff0c\u589e\u5f3a\u795e\u7ecf\u56de\u8def\u53ef\u5851\u6027\uff0c\u4fc3\u8fdb\u635f\u4f24\u540e\u529f\u80fd\u6062\u590d<\/strong>\u3002\u6210\u4f53\u5927\u8111\u5b58\u5728\u795e\u7ecf\u53d1\u751f\u8fd9\u4e00\u53d1\u73b0\u63a8\u7ffb\u4e86\u4f20\u7edf\u8ba4\u77e5\u3002<\/p>\n<h2 id=\"h-\u6210\u4eba\u795e\u7ecf\u518d\u751f\u7684\u5386\u53f2\u80cc\u666f\"><span class=\"ez-toc-section\" id=\"%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%86%8D%E7%94%9F%E7%9A%84%E5%8E%86%E5%8F%B2%E8%83%8C%E6%99%AF\"><\/span><strong>\u6210\u4eba\u795e\u7ecf\u518d\u751f\u7684\u5386\u53f2\u80cc\u666f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>\u8ba4\u77e5\u98a0\u8986\u4e0e\u79d1\u5b66\u9a8c\u8bc1\uff1a<\/strong>\u5728\u795e\u7ecf\u79d1\u5b66\u9886\u57df\uff0c\u4f20\u7edf\u89c2\u70b9\u8ba4\u4e3a\u54fa\u4e73\u52a8\u7269\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\uff08CNS\uff09\u4ea7\u751f\u65b0\u795e\u7ecf\u7ec6\u80de\uff08\u795e\u7ecf\u53d1\u751f\uff09\u7684\u80fd\u529b\u5728\u51fa\u751f\u540e\u4e0d\u53ef\u9006\u5730\u505c\u6b62\u2014\u2014\u8fd9\u4e0e\u80da\u80ce\u53d1\u80b2\u9636\u6bb5\u548c\u591a\u6570\u5176\u4ed6\u6210\u4f53\u7ec4\u7ec7\u7684\u60c5\u51b5\u622a\u7136\u4e0d\u540c\uff0c\u8fd9\u4e00\u8ba4\u77e5\u6301\u7eed\u81f31990\u5e74\u4ee3\u521d\u3002<\/p>\n<p>1960\u5e74\u4ee3Altman\u56e2\u961f\u901a\u8fc7\u653e\u5c04\u6027\u6807\u8bb0\u9996\u6b21\u5728\u6210\u5e74\u5927\u9f20\u6d77\u9a6c\u4f53\u53d1\u73b0\u795e\u7ecf\u53d1\u751f\u8bc1\u636e\uff1b1980\u5e74\u4ee3Nottebohm\u5728\u9e23\u79bd\u5b66\u4e60\u4e2d\u8bc1\u5b9e\u65b0\u751f\u795e\u7ecf\u5143\u5bf9\u8bb0\u5fc6\u5f62\u6210\u7684\u8d21\u732e\uff0c\u5f7b\u5e95\u9769\u65b0\u8ba4\u77e5\u3002<strong>\u540e\u7eed\u7814\u7a76\u786e\u7acb\u4eba\u7c7b\u6d77\u9a6c\u7ec6\u80de\u53ef\u4ee5\u5728\u5176\u4e00\u751f\u4e2d\u7684\u6bcf\u4e00\u523b\u6301\u7eed\u4ea7\u751f\u65b0\u7684\u795e\u7ecf\u5143\u3002\u5e76\u8bc1\u5b9e\u8be5\u73b0\u8c61\u5e7f\u6cdb\u5b58\u5728\u4e8e\u54fa\u4e73\u52a8\u7269\u53ca\u810a\u690e\u52a8\u7269\u7684\u9f7f\u72b6\u56de\u3001\u8111\u5ba4\u4e0b\u533a\u53ca\u591a\u8111\u533a\uff0c\u6807\u5fd7\u7740\u6210\u4f53\u795e\u7ecf\u53ef\u5851\u6027\u7684\u79d1\u5b66\u5171\u8bc6\u5f62\u6210<\/strong>The<\/p>\n<p><strong>\u673a\u5236\u7279\u6027\u4e0e\u7814\u7a76\u6f14\u8fdb\uff1a<\/strong>\u6210\u4f53\u795e\u7ecf\u53d1\u751f\u662f\u6307\u8111\u5185\u795e\u7ecf\u5e72\u7ec6\u80de\u5f62\u6210\u5b8c\u5168\u53d1\u80b2\u5e76\u5177\u6709\u529f\u80fd\u7684\u795e\u7ecf\u5143\u3002\u8be5\u8fc7\u7a0b\u6db5\u76d6\u4ece\u524d\u4f53\u7ec6\u80de\u7684\u521d\u59cb\u5206\u88c2\u5230\u6210\u719f\u3001\u5177\u6709\u529f\u80fd\u7684\u65b0\u795e\u7ecf\u5143\u7684\u5efa\u7acb\u548c\u5b58\u6d3b\u7684\u6240\u6709\u9636\u6bb5\u3002<\/p>\n<p>\u6838\u5fc3\u533a\u57df\u96c6\u4e2d\u4e8e\u6d77\u9a6c\u9f7f\u72b6\u56de\u4e0e\u8111\u5ba4\u4e0b\u533a\u3002\u5176\u591a\u9636\u6bb5\u8fdb\u7a0b\u6db5\u76d6\u589e\u6b96\u3001\u8fc1\u79fb\u3001\u5206\u5316\u4e0e\u6574\u5408\uff0c\u6f14\u5316\u8fc7\u7a0b\u4e2d\u901a\u8fc7\u7cbe\u5bc6\u8c03\u63a7\u795e\u7ecf\u5143\u4ea7\u91cf\u4ee5\u9002\u5e94\u8111\u90e8\u7ed3\u6784\u4e0e\u73af\u5883\u9700\u6c42\u3002<\/p>\n<p>\u6210\u4f53\u795e\u7ecf\u5e72\u7ec6\u80de\u51ed\u501f\u957f\u671f\u81ea\u6211\u66f4\u65b0\u548c\u591a\u5411\u5206\u5316\u80fd\u529b\u6784\u6210\u8be5\u8fc7\u7a0b\u57fa\u7840\u3002\u8be5\u9886\u57df\u5df2\u4ece\u4e89\u8bae\u9636\u6bb5\u53d1\u5c55\u4e3a\u63a2\u7d22\u795e\u7ecf\u518d\u751f\u673a\u5236\u4e0e\u6cbb\u7597\u6f5c\u529b\u7684\u524d\u6cbf\u65b9\u5411\uff0c\u6301\u7eed\u63a8\u52a8\u5927\u8111\u4fee\u590d\u7b56\u7565\u7684\u521b\u65b0\uff08\u8be6\u89c1\u88681\uff09\u3002<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 1155px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201741-68d3e1654d1c7.jpg\" alt=\"\u88681\uff1a\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u53f2\u4e0a\u91cd\u8981\u8f6c\u6298\u70b9\u548c\u8fdb\u5c55\u5217\u8868\uff1a\u672c\u8868\u5217\u51fa\u4e86\u8fc7\u53bb\u51e0\u5341\u5e74\u5f71\u54cd\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7814\u7a76\u7684\u5173\u952e\u53d1\u73b0\u548c\u53d1\u5c55\u3002\u5b83\u6309\u65f6\u95f4\u987a\u5e8f\u5217\u51fa\u4e86\u5851\u9020\u6211\u4eec\u76ee\u524d\u5bf9\u6210\u4eba\u5927\u8111\u795e\u7ecf\u53d1\u751f\u8ba4\u8bc6\u7684\u5f00\u521b\u6027\u7814\u7a76\u3001\u6280\u672f\u53d1\u5c55\u548c\u7406\u8bba\u8fdb\u6b65\u3002\" width=\"1145\" height=\"759\" title=\"\"><p class=\"wp-caption-text\">\u88681\uff1a\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u53f2\u4e0a\u91cd\u8981\u8f6c\u6298\u70b9\u548c\u8fdb\u5c55\u5217\u8868\uff1a\u672c\u8868\u5217\u51fa\u4e86\u8fc7\u53bb\u51e0\u5341\u5e74\u5f71\u54cd\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7814\u7a76\u7684\u5173\u952e\u53d1\u73b0\u548c\u53d1\u5c55\u3002\u5b83\u6309\u65f6\u95f4\u987a\u5e8f\u5217\u51fa\u4e86\u5851\u9020\u6211\u4eec\u76ee\u524d\u5bf9\u6210\u4eba\u5927\u8111\u795e\u7ecf\u53d1\u751f\u8ba4\u8bc6\u7684\u5f00\u521b\u6027\u7814\u7a76\u3001\u6280\u672f\u53d1\u5c55\u548c\u7406\u8bba\u8fdb\u6b65\u3002<\/p><\/div><figcaption><\/figcaption><\/figure>\n<h2 id=\"h-\u6210\u4eba\u795e\u7ecf\u518d\u751f\u7684\u5e38\u89c1\u4f4d\u7f6e\"><span class=\"ez-toc-section\" id=\"%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%86%8D%E7%94%9F%E7%9A%84%E5%B8%B8%E8%A7%81%E4%BD%8D%E7%BD%AE\"><\/span><strong>\u6210\u4eba\u795e\u7ecf\u518d\u751f\u7684\u5e38\u89c1\u4f4d\u7f6e<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3 id=\"h-\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u5e38\u89c1\u4f4d\u7f6e\u4e4b\u4e00\u55c5\u7403\u4e2d\u7684\u6210\u4eba\u795e\u7ecf\u53d1\u751f\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F%E7%9A%84%E5%B8%B8%E8%A7%81%E4%BD%8D%E7%BD%AE%E4%B9%8B%E4%B8%80%E5%97%85%E7%90%83%E4%B8%AD%E7%9A%84%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F\"><\/span><strong>\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u5e38\u89c1\u4f4d\u7f6e\u4e4b\u4e00\u55c5\u7403\u4e2d\u7684\u6210\u4eba\u795e\u7ecf\u53d1\u751f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>\u55c5\u7403\u4e2d\u7684\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u53d1\u751f\u673a\u5236\u4e0e\u89e3\u5256\u57fa\u7840\uff1a<\/strong>\u55c5\u7403\u662f\u810a\u690e\u52a8\u7269\u55c5\u89c9\u5904\u7406\u7684\u6838\u5fc3\u8111\u533a\uff0c\u5176\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u5177\u6709\u7ec8\u8eab\u6301\u7eed\u6027\uff0c\u4e3b\u8981\u4f9d\u8d56\u8111\u5ba4\u4e0b\u533a\uff08SVZ\uff09\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\u3002SVZ\u4e2d\u7684B1\u578b\u5e72\u7ec6\u80de\uff08\u8868\u8fbeGFAP\u7b49\u6807\u5fd7\u7269\uff09\u7ecf\u4e0d\u5bf9\u79f0\u5206\u88c2\u4ea7\u751f\u7956\u7ec6\u80de\uff0c\u65b0\u751f\u7ec6\u80de\u6cbf\u543b\u4fa7\u8fc1\u79fb\u6d41\uff08RMS\uff09\u5b9a\u5411\u8fc1\u79fb\u81f3\u55c5\u7403\uff0c\u6700\u7ec8\u5206\u5316\u4e3a\u9897\u7c92\u7ec6\u80de\uff08\u536095%\uff09\u53ca\u5c11\u91cf\u7956\u7ec6\u80de\u4e9a\u578b\u3002<\/p>\n<p>\u8fd9\u4e00\u591a\u9636\u6bb5\u8fc7\u7a0b<strong>\uff08\u589e\u6b96-\u8fc1\u79fb-\u5206\u5316-\u6574\u5408\uff09<\/strong>\u53d7\u7cbe\u5bc6\u8c03\u63a7\uff0c\u4e3a\u55c5\u7403\u63d0\u4f9b\u6301\u7eed\u795e\u7ecf\u5143\u8865\u5145\uff0c\u662f\u7ef4\u6301\u55c5\u89c9\u53ef\u5851\u6027\u7684\u7ed3\u6784\u57fa\u7840\uff08\u56fe1-2\u793a\u8fc1\u79fb\u8def\u5f84\uff09\u3002<\/p>\n<figure class=\"aligncenter size-full\">\n<p><div style=\"width: 812px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201741-68d3e1657e260.jpg\" alt=\"\u56fe1\uff1a\u6210\u5e74\u556e\u9f7f\u52a8\u7269\u5927\u8111\u7684\u77e2\u72b6\u56fe\uff08\u5de6\u4fa7\u4e3a\u55c5\u7403\uff0c\u53f3\u4fa7\u4e3a\u5c0f\u8111\uff09\u663e\u793a\u4e86\u8111\u5ba4\u4e0b\u533a-\u55c5\u7403 (SVZ-OB) \u7cfb\u7edf\u3002\" width=\"802\" height=\"394\" title=\"\"><p class=\"wp-caption-text\">\u56fe1\uff1a\u6210\u5e74\u556e\u9f7f\u52a8\u7269\u5927\u8111\u7684\u77e2\u72b6\u56fe\uff08\u5de6\u4fa7\u4e3a\u55c5\u7403\uff0c\u53f3\u4fa7\u4e3a\u5c0f\u8111\uff09\u663e\u793a\u4e86\u8111\u5ba4\u4e0b\u533a-\u55c5\u7403 (SVZ-OB) \u7cfb\u7edf\u3002<\/p><\/div><\/figure>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>SVZ\u4f4d\u4e8e\u4fa7\u8111\u5ba4 (LV\uff0c\u663e\u793a\u4e3a\u84dd\u8272) \u6cbf\u7ebf\uff0c\u662f\u6301\u7eed\u795e\u7ecf\u53d1\u751f\u7684\u90e8\u4f4d\u3002\u65b0\u751f\u795e\u7ecf\u5143 (A \u7ec6\u80de) \u7ec4\u7ec7\u6210\u8fc1\u79fb\u94fe (\u7ea2\u7ebf)\uff0c\u5728SVZ\u5185\u6784\u6210\u590d\u6742\u7684\u7f51\u7edc\u3002<\/p><\/blockquote>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 729px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201741-68d3e1658886a.jpg\" alt=\"\u56fe2\uff1a\u8fd9\u662f\u55c5\u7403\u795e\u7ecf\u7f51\u7edc\u7684\u793a\u610f\u56fe\u3002\" width=\"719\" height=\"649\" title=\"\"><p class=\"wp-caption-text\">\u56fe2\uff1a\u8fd9\u662f\u55c5\u7403\u795e\u7ecf\u7f51\u7edc\u7684\u793a\u610f\u56fe\u3002<\/p><\/div><figcaption><\/figcaption><\/figure>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u55c5\u89c9\u795e\u7ecf\u5143 (OSN) \u5bf9\u76f8\u540c\u7684\u6c14\u5473 (\u7528\u84dd\u8272\u3001\u9ec4\u8272\u548c\u7ea2\u8272\u8868\u793a) \u8fdb\u884c\u8c03\u8282\uff0c\u6295\u5c04\u5230\u76f8\u540c\u7684\u55c5\u7403\u5c0f\u7403\u5e76\u5728\u5176\u4e2d\u8fdb\u884c\u7a81\u89e6\u3002<\/p><\/blockquote>\n<p><strong>\u529f\u80fd\u610f\u4e49\u4e0e\u6cbb\u7597\u6f5c\u529b\uff1a<\/strong>\u55c5\u7403\u795e\u7ecf\u53d1\u751f\u7684\u6838\u5fc3\u529f\u80fd\u5728\u4e8e\u7ef4\u6301\u55c5\u89c9\u9002\u5e94\u6027\uff1a\u901a\u8fc7\u9897\u7c92\u7ec6\u80de\u7684\u6301\u7eed\u518d\u751f\u4e0e\u66f4\u66ff\uff0c\u5927\u8111\u53ef\u52a8\u6001\u4f18\u5316\u55c5\u89c9\u56de\u8def\u4ee5\u54cd\u5e94\u73af\u5883\u53d8\u5316\u3002<\/p>\n<p>\u5176\u79d1\u5b66\u4ef7\u503c\u4e0d\u4ec5\u63ed\u793a\u6210\u4f53\u795e\u7ecf\u53ef\u5851\u6027\uff0c\u66f4\u62d3\u5c55\u81f3\u75be\u75c5\u6cbb\u7597\u9886\u57df\uff1a<strong>SVZ\u795e\u7ecf\u6bcd\u7ec6\u80de\u53ef\u8fc1\u79fb\u81f3\u57fa\u5e95\u8282\u53ca\u76ae\u5c42\uff08\u5e15\u91d1\u68ee\u75c5\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u9000\u5316\u9776\u533a\uff09\uff0c\u4e3a\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u5e72\u7ec6\u80de\u7597\u6cd5\u63d0\u4f9b\u65b0\u8def\u5f84<\/strong>\u3002\u6b64\u5916\uff0c\u55c5\u7403\u4e2d\u95f4\u795e\u7ecf\u5143\u901a\u8fc7\u6574\u5408\u5230\u55c5\u89c9\u4fe1\u606f\u4f20\u9012\u901a\u8def\uff08\u8fde\u63a5\u55c5\u4e0a\u76ae\u4e0e\u6295\u5c04\u795e\u7ecf\u5143\uff09\uff0c\u76f4\u63a5\u652f\u6491\u55c5\u89c9\u529f\u80fd\u7684\u7a33\u6001\u4e0e\u53ef\u5851\u6027\uff08\u56fe1-2\u793a\u7a81\u89e6\u8fde\u63a5\uff09\u3002<\/p>\n<h3 id=\"h-\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u5e38\u89c1\u4f4d\u7f6e\u4e4b\u4e00\u6210\u4eba\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F%E7%9A%84%E5%B8%B8%E8%A7%81%E4%BD%8D%E7%BD%AE%E4%B9%8B%E4%B8%80%E6%88%90%E4%BA%BA%E6%B5%B7%E9%A9%AC%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F\"><\/span><strong>\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u5e38\u89c1\u4f4d\u7f6e\u4e4b\u4e00<\/strong><strong>\u6210\u4eba\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u4f20\u7edf\u89c2\u70b9\u8ba4\u4e3a\u795e\u7ecf\u53d1\u751f\uff08\u65b0\u795e\u7ecf\u5143\u5f62\u6210\uff09\u4ec5\u5b58\u5728\u4e8e\u80da\u80ce\u53ca\u65e9\u671f\u53d1\u80b2\u9636\u6bb5\uff0c\u6210\u4eba\u5927\u8111\u51e0\u4e4e\u65e0\u518d\u751f\u80fd\u529b\uff08\u56fe2\uff09\u3002\u7136\u800c\uff0c\u8fd1\u51e0\u5341\u5e74\u7684\u7a81\u7834\u6027\u7814\u7a76\u98a0\u8986\u4e86\u8fd9\u4e00\u8ba4\u77e5\uff1a\u6210\u5e74\u54fa\u4e73\u52a8\u7269\u5927\u8111\u7684\u7279\u5b9a\u533a\u57df\uff08\u5c24\u5176\u662f\u6d77\u9a6c\u4f53\uff09\u7ec8\u751f\u4fdd\u7559\u4ea7\u751f\u65b0\u795e\u7ecf\u5143\u7684\u80fd\u529b\u3002<\/p>\n<h4 id=\"h-\u6210\u4eba\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f\u7684\u89e3\u5256\u5b9a\u4f4d\u4e0e\u53d1\u751f\u673a\u5236-\u6d77\u9a6c\u9f7f\u72b6\u56de-dg-\u662f\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u6838\u5fc3\u533a\u57df-\u5176\u9897\u7c92\u7ec6\u80de\u4e0b\u533a-sgz-\u4f5c\u4e3a\u795e\u7ecf\u5e72\u7ec6\u80de\u5de2\u7a74-\u542b\u9759\u606f\u60011\u578b\u653e\u5c04\u72b6\u80f6\u8d28\u6837\u5e72\u7ec6\u80de-\u8868\u8fbegfap\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%88%90%E4%BA%BA%E6%B5%B7%E9%A9%AC%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F%E7%9A%84%E8%A7%A3%E5%89%96%E5%AE%9A%E4%BD%8D%E4%B8%8E%E5%8F%91%E7%94%9F%E6%9C%BA%E5%88%B6%EF%BC%9A%E6%B5%B7%E9%A9%AC%E9%BD%BF%E7%8A%B6%E5%9B%9E%EF%BC%88DG%EF%BC%89%E6%98%AF%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F%E7%9A%84%E6%A0%B8%E5%BF%83%E5%8C%BA%E5%9F%9F%EF%BC%8C%E5%85%B6%E9%A2%97%E7%B2%92%E7%BB%86%E8%83%9E%E4%B8%8B%E5%8C%BA%EF%BC%88SGZ%EF%BC%89%E4%BD%9C%E4%B8%BA%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E5%B7%A2%E7%A9%B4%EF%BC%8C%E5%90%AB%E9%9D%99%E6%81%AF%E6%80%811%E5%9E%8B%E6%94%BE%E5%B0%84%E7%8A%B6%E8%83%B6%E8%B4%A8%E6%A0%B7%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88%E8%A1%A8%E8%BE%BEGFAP%EF%BC%89%E3%80%82\"><\/span><strong>\u6210\u4eba\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f\u7684\u89e3\u5256\u5b9a\u4f4d\u4e0e\u53d1\u751f\u673a\u5236\uff1a<\/strong>\u6d77\u9a6c\u9f7f\u72b6\u56de\uff08DG\uff09\u662f\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u6838\u5fc3\u533a\u57df\uff0c\u5176\u9897\u7c92\u7ec6\u80de\u4e0b\u533a\uff08SGZ\uff09\u4f5c\u4e3a\u795e\u7ecf\u5e72\u7ec6\u80de\u5de2\u7a74\uff0c\u542b\u9759\u606f\u60011\u578b\u653e\u5c04\u72b6\u80f6\u8d28\u6837\u5e72\u7ec6\u80de\uff08\u8868\u8fbeGFAP\uff09\u3002<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<h4 id=\"h-\u795e\u7ecf\u53d1\u751f\u7ecf\u5386\u4e94\u9636\u6bb5\u8fde\u7eed\u8fc7\u7a0b\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F%E7%BB%8F%E5%8E%86%E4%BA%94%E9%98%B6%E6%AE%B5%E8%BF%9E%E7%BB%AD%E8%BF%87%E7%A8%8B%EF%BC%9A\"><\/span>\u795e\u7ecf\u53d1\u751f\u7ecf\u5386\u4e94\u9636\u6bb5\u8fde\u7eed\u8fc7\u7a0b\uff1a<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<ul class=\"wp-block-list\">\n<li>\u9636\u6bb51\uff1a1\u578b\u7ec6\u80de\u6fc0\u6d3b<\/li>\n<li>\u9636\u6bb52\uff1a\u5206\u5316\u4e3a\u8fc7\u6e21\u6027\u4e2d\u95f4\u7956\u7ec6\u80de\uff08\u8868\u8fbe\u53cc\u76ae\u8d28\u7d20\uff09<\/li>\n<li>\u9636\u6bb53\uff1a\u8fc1\u79fb\u4e3a\u795e\u7ecf\u6bcd\u7ec6\u80de<\/li>\n<li>\u9636\u6bb54\uff1a\u6210\u719f\u4e3a\u9897\u7c92\u795e\u7ecf\u5143\uff08\u552f\u4e00\u795e\u7ecf\u5143\u7c7b\u578b\uff09<\/li>\n<li>\u9636\u6bb55\uff1a\u7a81\u89e6\u6574\u5408\u5165\u6d77\u9a6c\u56de\u8def<\/li>\n<\/ul>\n<p>\u65b0\u795e\u7ecf\u5143\u8fc1\u79fb\u8ddd\u79bb\u77ed\uff0c\u76f4\u63a5\u53c2\u4e0e\u6d77\u9a6c\u8ba4\u77e5\u529f\u80fd\u73af\u8def\u6784\u5efa\uff08\u56fe2\u793a\u7ec6\u80de\u5206\u5316\u8def\u5f84\uff09\u3002<\/p>\n<h2 id=\"h-\u6210\u4eba\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f\u7684\u529f\u80fd\u7279\u6027\u4e0e\u4e34\u5e8a\u610f\u4e49\"><span class=\"ez-toc-section\" id=\"%E6%88%90%E4%BA%BA%E6%B5%B7%E9%A9%AC%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F%E7%9A%84%E5%8A%9F%E8%83%BD%E7%89%B9%E6%80%A7%E4%B8%8E%E4%B8%B4%E5%BA%8A%E6%84%8F%E4%B9%89\"><\/span>\u6210\u4eba\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f\u7684\u529f\u80fd\u7279\u6027\u4e0e\u4e34\u5e8a\u610f\u4e49<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f\u5177\u6709\u53cc\u91cd\u72ec\u7279\u6027\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u529f\u80fd\u5c42\u9762\uff1a<\/strong>\u65b0\u751f\u9897\u7c92\u795e\u7ecf\u5143\u901a\u8fc7\u7a81\u89e6\u6574\u5408\u76f4\u63a5\u8c03\u63a7\u5b66\u4e60\u3001\u8bb0\u5fc6\u53ca\u7a7a\u95f4\u5bfc\u822a\u80fd\u529b\uff0c\u533a\u522b\u4e8e\u55c5\u7403\u7684\u55c5\u89c9\u7279\u5f02\u6027\uff1b<\/li>\n<li><strong>\u7ec6\u80de\u5c42\u9762\uff1a<\/strong>\u4ec5\u4ea7\u751f\u5174\u594b\u6027\u9897\u7c92\u7ec6\u80de\uff08\u4e0e\u55c5\u7403\u7684\u6291\u5236\u6027\u4e2d\u95f4\u795e\u7ecf\u5143\u5f62\u6210\u9c9c\u660e\u5bf9\u6bd4\uff09\uff0c\u4e14\u53d1\u751f\u7387\u968f\u5e74\u9f84\u663e\u8457\u964d\u4f4e\u3002<\/li>\n<\/ul>\n<p><strong>\u6210\u4eba\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f\u5176\u79d1\u5b66\u4ef7\u503c\u5728\u4e8e\uff1a<\/strong><\/p>\n<ul class=\"wp-block-list\">\n<li>\u2460\u4e3a\u5927\u8111\u53ef\u5851\u6027\u63d0\u4f9b\u7ec6\u80de\u7ea7\u8bc1\u636e\uff1b<\/li>\n<li>\u2461\u63ed\u793a\u8ba4\u77e5\u8870\u9000\u75be\u75c5\u7684\u6f5c\u5728\u673a\u5236\uff08\u5982\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e2d\u795e\u7ecf\u53d1\u751f\u51cf\u5c11\uff09\uff1b<\/li>\n<li>\u2462\u4e3a\u5f00\u53d1\u795e\u7ecf\u518d\u751f\u7597\u6cd5\uff08\u5982\u9776\u5411SGZ\u5e72\u7ec6\u80de\u6fc0\u6d3b\uff09\u63d0\u4f9b\u7406\u8bba\u4f9d\u636e\u3002<\/li>\n<\/ul>\n<h3 id=\"h-\u5176\u4ed6\u5927\u8111\u533a\u57df\u7684\u6210\u4eba\u795e\u7ecf\u53d1\u751f\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%85%B6%E4%BB%96%E5%A4%A7%E8%84%91%E5%8C%BA%E5%9F%9F%E7%9A%84%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F\"><\/span><strong>\u5176\u4ed6\u5927\u8111\u533a\u57df\u7684\u6210\u4eba\u795e\u7ecf\u53d1\u751f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u6709\u4eba\u63d0\u51fa\uff0c<strong>\u9664\u4e86\u8111\u5ba4\u4e0b\u533a\u548c\u9f7f\u72b6\u56de\u7684\u795e\u7ecf\u53d1\u751f\u5916\uff0c\u5927\u8111\u7684\u5176\u4ed6\u533a\u57df\u4e5f\u4f1a\u4ea7\u751f\u5c11\u91cf\u65b0\u751f\u795e\u7ecf\u5143\u3002\u8fd9\u4e9b\u533a\u57df\u5305\u62ec\u5927\u8111\u7684\u65b0\u76ae\u8d28\u3001\u7eb9\u72b6\u4f53\u3001\u674f\u4ec1\u6838\u3001\u9ed1\u8d28\u3001\u7b2c\u4e09\u548c\u7b2c\u56db\u8111\u5ba4<\/strong>\u3002\u8fd9\u4e9b\u533a\u57df\u795e\u7ecf\u7403\u7684\u53d1\u80b2\u8868\u660e\u5b58\u5728\u795e\u7ecf\u5e72\u7ec6\u80de\u3002<\/p>\n<h2 id=\"h-\u68c0\u6d4b\u795e\u7ecf\u518d\u751f\u7ec6\u80de\u7c7b\u578b\u7684\u5206\u5b50\u6807\u5fd7\u7269\u6709\u54ea\u4e9b\"><span class=\"ez-toc-section\" id=\"%E6%A3%80%E6%B5%8B%E7%A5%9E%E7%BB%8F%E5%86%8D%E7%94%9F%E7%BB%86%E8%83%9E%E7%B1%BB%E5%9E%8B%E7%9A%84%E5%88%86%E5%AD%90%E6%A0%87%E5%BF%97%E7%89%A9%E6%9C%89%E5%93%AA%E4%BA%9B%EF%BC%9F\"><\/span>\u68c0\u6d4b\u795e\u7ecf\u518d\u751f\u7ec6\u80de\u7c7b\u578b\u7684\u5206\u5b50\u6807\u5fd7\u7269\u6709\u54ea\u4e9b\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u8fc7\u53bb\uff0c\u4eba\u7c7b\u6210\u4f53\u795e\u7ecf\u53d1\u751f\u7684\u9996\u6b21\u786e\u8bc1\u57fa\u4e8e\u6eb4\u8131\u6c27\u5c3f\u82f7\u8109\u51b2\u8ffd\u8e2a\u5b9e\u9a8c\u3002\u8be5\u6280\u672f\u901a\u8fc7\u514d\u75ab\u8367\u5149\u6807\u8bb0\u56fa\u5b9a\u7ec4\u7ec7\uff0c\u7528\u4e8e\u6807\u8bb0\u6d3b\u4f53\u7ec4\u7ec7\u4e2d\u7684\u5206\u88c2\u7ec6\u80de\u5e76\u8ffd\u8e2a\u5176\u540e\u4ee3\u3002\u7814\u7a76\u8005\u5229\u7528\u6b64\u6cd5\uff0c\u5728\u66fe\u56e0\u8bca\u65ad\u76ee\u7684\u6ce8\u5c04\u6eb4\u8131\u6c27\u5c3f\u82f7\u7684\u764c\u75c7\u60a3\u8005\u5c38\u68c0\u6d77\u9a6c\u6837\u672c\u4e2d\u8bc1\u5b9e\u4e86\u795e\u7ecf\u53d1\u751f\u3002<\/p>\n<p>\u5982\u4eca\uff0c\u591a\u79cd\u514d\u75ab\u7ec6\u80de\u5316\u5b66\u6807\u5fd7\u7269\u88ab\u5e7f\u6cdb\u5e94\u7528\uff1aKi-67\u4f5c\u4e3a\u6709\u4e1d\u5206\u88c2\u6807\u5fd7\u7269\uff0cSOX2\u548c\u8111\u8102\u7ed3\u5408\u86cb\u767d\uff08BLBP\uff09\u6807\u8bb0\u653e\u5c04\u72b6\u80f6\u8d28\u6837\u5e72\u7ec6\u80de\uff0c\u53cc\u76ae\u8d28\u7d20\uff08DCX\uff09\u548c\u591a\u805a\u553e\u6db2\u9178-\u795e\u7ecf\u7ec6\u80de\u9ecf\u9644\u5206\u5b50\uff08PSA-NCAM\uff09\u6807\u8bb0\u65e9\u671f\u672a\u6210\u719f\u795e\u7ecf\u5143\uff0c\u7814\u7a76\u8005\u8fd8\u501f\u52a9\u7535\u955c\u6280\u672f\u7cbe\u786e\u5b9a\u4f4d\u795e\u7ecf\u53d1\u751f\u7684\u7279\u5b9a\u9636\u6bb5\uff08\u89c1\u88682\uff1b\u56fe3\uff09\u3002<\/p>\n<figure class=\"aligncenter size-full\">\n<p><div style=\"width: 724px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201741-68d3e16597bf7.jpg\" alt=\"\u88682\uff1a\u4e0b\u8868\u603b\u7ed3\u4e86\u7528\u4e8e\u8bc6\u522b\u53c2\u4e0e\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u7ec6\u80de\u7c7b\u578b\u7684\u5173\u952e\u5206\u5b50\u751f\u7269\u6807\u5fd7\u7269\u3002\" width=\"714\" height=\"408\" title=\"\"><p class=\"wp-caption-text\">\u88682\uff1a\u4e0b\u8868\u603b\u7ed3\u4e86\u7528\u4e8e\u8bc6\u522b\u53c2\u4e0e\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u7ec6\u80de\u7c7b\u578b\u7684\u5173\u952e\u5206\u5b50\u751f\u7269\u6807\u5fd7\u7269\u3002<\/p><\/div><\/figure>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 736px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201741-68d3e165a2ce4.jpg\" alt=\"\u56fe3\uff1a\u8be5\u56fe\u5c55\u793a\u4e86\u8c03\u8282\u6210\u4f53\u795e\u7ecf\u53d1\u751f\u7684\u56e0\u7d20\u3002\" width=\"726\" height=\"481\" title=\"\"><p class=\"wp-caption-text\">\u56fe3\uff1a\u8be5\u56fe\u5c55\u793a\u4e86\u8c03\u8282\u6210\u4f53\u795e\u7ecf\u53d1\u751f\u7684\u56e0\u7d20\u3002<\/p><\/div><figcaption><\/figcaption><\/figure>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u5b83\u5bf9\u514d\u75ab\u53cd\u5e94\u548c\u4ee3\u8c22\u56e0\u7d20\u7b49\u5173\u952e\u5f71\u54cd\u56e0\u7d20\u8fdb\u884c\u4e86\u5206\u7c7b\u548c\u603b\u7ed3\u3002\u8be5\u56fe\u6e05\u6670\u5730\u5c55\u73b0\u4e86\u8fd9\u4e9b\u56e0\u7d20\u4e4b\u95f4\u590d\u6742\u7684\u76f8\u4e92\u4f5c\u7528<\/p><\/blockquote>\n<h2 id=\"h-\u4ec0\u4e48\u662f\u6210\u4eba\u795e\u7ecf\u518d\u751f\u7684\u8c03\u63a7\u673a\u5236\"><span class=\"ez-toc-section\" id=\"%E4%BB%80%E4%B9%88%E6%98%AF%E6%88%90%E4%BA%BA%E7%A5%9E%E7%BB%8F%E5%86%8D%E7%94%9F%E7%9A%84%E8%B0%83%E6%8E%A7%E6%9C%BA%E5%88%B6%EF%BC%9F\"><\/span><strong>\u4ec0\u4e48\u662f\u6210\u4eba\u795e\u7ecf\u518d\u751f\u7684\u8c03\u63a7\u673a\u5236\uff1f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u7406\u89e3\u6d77\u9a6c\u4f53\u3001\u55c5\u7403\u53ca\u5176\u4ed6\u8111\u533a\u7684\u6210\u4eba\u795e\u7ecf\u518d\u751f\u8c03\u63a7\u673a\u5236\uff0c\u662f\u63a2\u7d22\u795e\u7ecf\u53ef\u5851\u6027\u590d\u6742\u6027\u7684\u5173\u952e\u4e00\u6b65\u3002\u8fd9\u4e00\u52a8\u6001\u8fc7\u7a0b<strong>\u53d7\u5185\u5728\u4e0e\u5916\u5728\u56e0\u7d20\u7684\u53cc\u5411\u5f71\u54cd\uff0c\u5171\u540c\u5851\u9020\u7ec6\u80de\u589e\u6b96\u3001\u5206\u5316\u4e0e\u5b58\u6d3b\u7684\u52a8\u6001\u5e73\u8861<\/strong>\u3002\u6df1\u5165\u89e3\u6790\u8c03\u63a7\u56e0\u5b50\u5bf9\u795e\u7ecf\u5e72\u7ec6\u80de\uff08\u9897\u7c92\u7ec6\u80de\u4e0b\u533a\u53ca\u55c5\u7403\u5185\uff09\u5206\u5316\u4e3a\u795e\u7ecf\u5143\u7684\u4f5c\u7528\uff0c\u5c06\u4e3a\u54fa\u4e73\u52a8\u7269\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u7684\u521b\u65b0\u7597\u6cd5\u63d0\u4f9b\u5173\u952e\u8def\u5f84\u3002<\/p>\n<p>\u5185\u5728\u56e0\u7d20\u6839\u690d\u4e8e\u9057\u4f20\u7a0b\u5e8f\uff0c\u4e3b\u5bfc\u6d77\u9a6c\u4e0e\u55c5\u7403\u7684\u795e\u7ecf\u53d1\u80b2\u57fa\u7840\u3002\u795e\u7ecf\u53d1\u751f\u540c\u65f6\u53d7\u5916\u6e90\u73af\u5883\u56e0\u7d20\u7cbe\u5bc6\u8c03\u63a7\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u6b63\u5411\u4fc3\u8fdb\uff1a<\/strong>\u5bcc\u96c6\u73af\u5883\u523a\u6fc0\u3001\u81ea\u4e3b\u8fd0\u52a8\u53ca\u8425\u517b\u996e\u98df\u663e\u8457\u63d0\u5347\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f\u6c34\u5e73\uff1b<\/li>\n<li><strong>\u8d1f\u5411\u6291\u5236\uff1a<\/strong>\u6162\u6027\u708e\u75c7\u3001\u8870\u8001\u8fdb\u7a0b\u4e0e\u5fc3\u7406\u538b\u529b\u5219\u5f3a\u529b\u524a\u5f31\u8be5\u8fc7\u7a0b\u3002<\/li>\n<\/ul>\n<p>\u6700\u65b0\u7814\u7a76\u9501\u5b9a\u4e94\u7c7b\u6838\u5fc3\u8c03\u63a7\u4f53\u7cfb\u2014\u2014<strong>\u4fe1\u53f7\u8f6c\u5bfc\u901a\u8def\u3001\u8840\u7ba1\/\u514d\u75ab\u7cfb\u7edf\u3001\u4ee3\u8c22\u56e0\u5b50\u53ca\u8868\u89c2\u9057\u4f20\u8c03\u63a7<\/strong>\uff08\u56fe3\uff09\uff0c\u5176\u5931\u8c03\u53ef\u80fd\u76f4\u63a5\u5173\u8054\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u53d1\u751f\u3002<\/p>\n<p><strong>1.Sonic Hedgehog\u4fe1\u53f7\u901a\u8def\u7684\u6838\u5fc3\u8c03\u63a7\u5730\u4f4d\uff1a<\/strong>Sonic Hedgehog\u4fe1\u53f7\u901a\u8def\u662f\u53d1\u80b2\u4e0e\u6210\u4f53\u795e\u7ecf\u53d1\u751f\u7684\u53cc\u91cd\u8c03\u63a7\u67a2\u7ebd\u3002\u8f6c\u57fa\u56e0\u5c0f\u9f20\u5b9e\u9a8c\u8bc1\u5b9e\uff0c\u5176\u529f\u80fd\u589e\u76ca\u6216\u7f3a\u5931\u5747\u76f4\u63a5\u51b3\u5b9aSVZ\u533a\u795e\u7ecf\u53d1\u751f\u6548\u80fd\u3002\u66f4\u5173\u952e\u7684\u662f\uff0c\u8be5\u901a\u8def\u540c\u65f6\u9a71\u52a8\u795e\u7ecf\u4fee\u590d\u8fdb\u7a0b\u2014\u2014\u4e2d\u98ce\u6a21\u578b\u4e2d\u5e73\u6ed1\u53d7\u4f53\u6fc0\u52a8\u5242\u901a\u8fc7\u6fc0\u6d3bShh\u901a\u8def\uff0c\u540c\u6b65\u63d0\u5347\u795e\u7ecf\u518d\u751f\u4e0e\u884c\u4e3a\u529f\u80fd\u6062\u590d\u3002<\/p>\n<p><strong>2.\u795e\u7ecf\u8425\u517b\u56e0\u5b50\u7684\u5fae\u73af\u5883\u652f\u6301\uff1a<\/strong>\u795e\u7ecf\u8425\u517b\u7d20\u5bb6\u65cf\uff08\u5c24\u4ee5BDNF\u4e3a\u6838\u5fc3\uff09\u6784\u6210\u795e\u7ecf\u53d1\u751f\u7684\u5fae\u73af\u5883\u4fe1\u53f7\u57fa\u77f3\u3002\u5185\u76ae\u7ec6\u80de\u6e90\u6027\u7684BDNF\u901a\u8fc7\u916a\u6c28\u9178\u6fc0\u9176\u901a\u8def\uff0c\u4e3a\u795e\u7ecf\u7956\u7ec6\u80de\u63d0\u4f9b\u4e09\u91cd\u4fdd\u969c\uff1a\u2460\u589e\u6b96\u6fc0\u6d3b\uff1b\u2461\u5206\u5316\u5bfc\u5411\uff1b\u2462\u5b58\u6d3b\u7ef4\u6301\uff0c\u8d2f\u7a7f\u6210\u4f53\u795e\u7ecf\u53d1\u751f\u5168\u7a0b\u3002<\/p>\n<p><strong>3.Wnt\u901a\u8def\u7684\u533a\u57df\u7279\u5f02\u6027\u8c03\u63a7\uff1a<\/strong>Wnt\u4fe1\u53f7\u4ee5\u5c42\u7ea7\u5316\u8c03\u63a7\u6a21\u5f0f\u5f71\u54cd\u6d77\u9a6c\u795e\u7ecf\u53d1\u751f\uff1a\u5728\u5206\u5b50\u5c42\u9762\u51b3\u5b9a\u5e72\u7ec6\u80de\u547d\u8fd0\uff0c\u5728\u7ec6\u80de\u5c42\u9762\u9a71\u52a8SVZ\/SGZ\u533a\u5e72\u7ec6\u80de\u6269\u589e\uff0c\u6700\u7ec8\u5728\u884c\u4e3a\u5c42\u9762\u5f71\u54cd\u8ba4\u77e5\u529f\u80fd\u3002\u5176\u72ec\u7279\u4ef7\u503c\u5728\u4e8e\u6fc0\u6d3b\u7ecf\u5178\u901a\u8def\u540e\uff0c\u53ef\u540c\u6b65\u5b9e\u73b0\u795e\u7ecf\u5e72\u7ec6\u80de\u81ea\u6211\u66f4\u65b0\u4e0e\u7956\u7ec6\u80de\u6c60\u6269\u5bb9\u3002<\/p>\n<p><strong>4.Notch-EGFR\u7684\u534f\u540c\u5e73\u8861\u7f51\u7edc\uff1a<\/strong>Notch\u4fe1\u53f7\u901a\u8fc7\u4e24\u79cd\u6a21\u5f0f\u7cbe\u7ec6\u8c03\u63a7\u795e\u7ecf\u53d1\u751f\uff1a\u2460Notch1\u7279\u5f02\u6027\u7ef4\u6301\u6d77\u9a6c\u5e72\u7ec6\u80de\u6c60\u7a33\u6001\uff1b\u2461\u4e0eEGFR\u5f62\u6210\u4fe1\u53f7\u8026\u5408\u6a21\u5757\uff0c\u901a\u8fc7\u52a8\u6001\u5e73\u8861SVZ\u533a\u5e72\u7ec6\u80de\u4e0e\u7956\u7ec6\u80de\u6bd4\u4f8b\uff0c\u9632\u6b62\u8fc7\u5ea6\u5206\u5316\u6216\u9759\u9ed8\u3002\u8fd9\u79cd\u534f\u540c\u662f\u5b9e\u73b0\u795e\u7ecf\u53d1\u751f\u53ef\u5851\u6027\u7684\u5173\u952e\u673a\u5236\u3002<\/p>\n<p><strong>5.VEGF\u7684\u795e\u7ecf-\u8840\u7ba1\u5076\u8054\u4f5c\u7528\uff1a<\/strong>VEGF\u7a81\u7834\u4f20\u7edf\u8840\u7ba1\u751f\u6210\u8303\u7574\uff0c\u76f4\u63a5\u53c2\u4e0e\u795e\u7ecf\u518d\u751f\uff1a\u2460\u56db\u79cd\u4e9a\u578b\u4e2dVEGF-A\/B\u5728\u795e\u7ecf\u53d1\u751f\u533a\u9ad8\u8868\u8fbe\uff1b\u2461\u901a\u8fc7\u53cc\u8def\u5f84\u4f5c\u7528\u2014\u2014\u65e2\u8bf1\u5bfc\u8840\u7ba1\u65b0\u751f\u6539\u5584\u5fae\u73af\u5883\uff0c\u53c8\u76f4\u63a5\u4fc3\u8fdb\u795e\u7ecf\u7956\u7ec6\u80de\u8fc1\u79fb\u6210\u719f\uff08\u56fe3\uff09\u3002\u5176\u5b9a\u4f4d\u63ed\u793a\u795e\u7ecf\u53d1\u751f\u4e0e\u8840\u7ba1\u7cfb\u7edf\u7684\u6df1\u5ea6\u5076\u8054\u3002<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u603b\u7ed3\uff1a\u4e94\u6761\u901a\u8def\u5f62\u6210\u7acb\u4f53\u8c03\u63a7\u7f51\u7edc\uff1aShh\u4e0eVEGF\u4fa7\u91cd\u635f\u4f24\u4fee\u590d\uff08\u56fe3\u793a\uff09\uff0cWnt\/Notch\u7ef4\u6301\u7a33\u6001\u5e73\u8861\uff0cBDNF\u63d0\u4f9b\u5fae\u73af\u5883\u652f\u6301\uff0c\u5171\u540c\u8d4b\u4e88\u6210\u4f53\u795e\u7ecf\u53d1\u751f\u52a8\u6001\u53ef\u5851\u6027\u3002<\/p><\/blockquote>\n<h2 id=\"h-\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u6cbb\u7597\u5e94\u7528\u53ca\u6838\u5fc3\u673a\u5236\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E6%B2%BB%E7%96%97%E5%BA%94%E7%94%A8%E5%8F%8A%E6%A0%B8%E5%BF%83%E6%9C%BA%E5%88%B6\"><\/span><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u6cbb\u7597\u5e94\u7528\u53ca\u6838\u5fc3\u673a\u5236<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u6838\u5fc3\u6cbb\u7597\u673a\u5236\uff1a<\/strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u51ed\u501f\u4e09\u91cd\u751f\u7269\u5b66\u7279\u6027\u2014\u2014\u81ea\u6211\u66f4\u65b0\u80fd\u529b\u3001\u591a\u5411\u5206\u5316\u6f5c\u80fd\uff08\u53ef\u8f6c\u5316\u4e3a\u795e\u7ecf\u5143\/\u80f6\u8d28\u7ec6\u80de\uff09\u53ca\u795e\u7ecf\u8425\u517b\u4f5c\u7528\uff0c\u901a\u8fc7\u4e24\u79cd\u9014\u5f84\u5b9e\u73b0\u6cbb\u7597\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u7ed3\u6784\u6027\u4fee\u590d\uff1a<\/strong>\u5206\u5316\u66ff\u4ee3\u6b7b\u4ea1\u795e\u7ecf\u5143\uff0c\u91cd\u5efa\u795e\u7ecf\u56de\u8def\uff1b<\/li>\n<li><strong>\u529f\u80fd\u6027\u4fdd\u62a4\uff1a<\/strong>\u5206\u6ccc\u8425\u517b\u56e0\u5b50\u5ef6\u7f13\u9000\u884c\u6027\u53d8\uff0c\u4fc3\u8fdb\u5185\u6e90\u6027\u4fee\u590d\u3002<\/li>\n<\/ul>\n<p>\u79fb\u690d\u7814\u7a76\u8bc1\u5b9e\u5176\u5bf9\u591a\u79cd\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u635f\u4f24\u548c\u9000\u884c\u6027\u75be\u75c5\u5177\u6709\u663e\u8457\u4fee\u590d\u6548\u679c\u3002<\/p>\n<h2 id=\"h-\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u4e34\u5e8a\u8f6c\u5316\u7b56\u7565\u4e0e\u79d1\u5b66\u57fa\u7840\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%BD%AC%E5%8C%96%E7%AD%96%E7%95%A5%E4%B8%8E%E7%A7%91%E5%AD%A6%E5%9F%BA%E7%A1%80\"><\/span>\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u4e34\u5e8a\u8f6c\u5316\u7b56\u7565\u4e0e\u79d1\u5b66\u57fa\u7840<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u6cbb\u7597\u7b56\u7565\u805a\u7126\u53cc\u8f68\u8def\u5f84\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u5185\u6e90\u6027\u6fc0\u6d3b\uff1a<\/strong>\u523a\u6fc0\u60a3\u8005\u81ea\u8eab\u795e\u7ecf\u5e72\u7ec6\u80de\u589e\u6b96\u5206\u5316\uff1b<\/li>\n<li><strong>\u5916\u6e90\u6027\u79fb\u690d\uff1a<\/strong>\u690d\u5165\u57f9\u517b\u6269\u589e\u7684\u6210\u4f53\u6e90\u5e72\u7ec6\u80de\u3002<\/li>\n<\/ul>\n<p>\u5176\u79d1\u5b66\u4f9d\u636e\u6e90\u4e8e\u6210\u4f53\u5927\u8111\u7ec8\u751f\u5b58\u5728\u795e\u7ecf\u53d1\u751f\u73b0\u8c61\u7684\u53d1\u73b0\uff0c\u4e3a\u7ec6\u80de\u66ff\u4ee3\u7597\u6cd5\u5960\u5b9a\u4e86\u751f\u7269\u5b66\u57fa\u7840\u3002\u5f53\u524d\u7ec6\u80de\u79fb\u690d\u6280\u672f\u5df2\u6210\u4e3a\u4fee\u590d\u75c5\u53d8\u795e\u7ecf\u7cfb\u7edf\u7684\u6838\u5fc3\u624b\u6bb5\u3002<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u6cbb\u7597\u4ef7\u503c\uff1a\u7a81\u7834\u4f20\u7edf\u836f\u7269\u5c40\u9650\uff0c\u4e3a\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u63d0\u4f9b\u75c5\u7406\u4fee\u6b63\u578b\u7597\u6cd5\uff0c\u5b9e\u73b0\u4ece\u75c7\u72b6\u63a7\u5236\u5411\u529f\u80fd\u91cd\u5efa\u7684\u8f6c\u5316\u3002<\/p><\/blockquote>\n<h2 id=\"h-\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u7684\u4e34\u5e8a\u5e94\u7528\u6709\u54ea\u4e9b\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E7%A5%9E%E7%BB%8F%E9%80%80%E8%A1%8C%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E5%BA%94%E7%94%A8%E6%9C%89%E5%93%AA%E4%BA%9B%EF%BC%9F\"><\/span><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u5e94\u7528\u6709\u54ea\u4e9b\uff1f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>1.\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u4e2d\u7684\u5e94\u7528\uff1a<\/strong>\u795e\u7ecf\u5e72\u7ec6\u80de\uff08NSC\uff09\u5728\u5e15\u91d1\u68ee\u75c5\u6cbb\u7597\u4e2d\u5c55\u73b0\u51fa\u7a81\u7834\u6027\u6f5c\u529b\uff0c\u5176\u6838\u5fc3\u7b56\u7565\u662f\u901a\u8fc7\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u5b9a\u5411\u66ff\u4ee3\u4e0e\u795e\u7ecf\u4fdd\u62a4\u53cc\u8def\u5f84\u4fee\u590d\u53d7\u635f\u7684\u9ed1\u8d28-\u7eb9\u72b6\u4f53\u901a\u8def\u3002\u5177\u4f53\u800c\u8a00\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u7ec6\u80de\u66ff\u4ee3\uff1a<\/strong>\u5c06\u4f53\u5916\u5206\u5316\u7684NSC\u6765\u6e90\u591a\u5df4\u80fa\u80fd\u524d\u4f53\u7ec6\u80de\u79fb\u690d\u81f3\u60a3\u8005\u7eb9\u72b6\u4f53\uff0c\u91cd\u5efa\u9000\u5316\u7684\u795e\u7ecf\u73af\u8def\uff08\u5982\u65e5\u672c\u4e34\u5e8a\u8bd5\u9a8cNCT04802733\u91c7\u7528iPSC-NSC\uff09\uff1b<\/li>\n<li><strong>\u65c1\u89c2\u8005\u6548\u5e94\uff1a<\/strong>\u79fb\u690d\u7684NSC\u6301\u7eed\u5206\u6ccc\u80f6\u8d28\u7ec6\u80de\u6e90\u6027\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff08GDNF\uff09\u548c\u8111\u6e90\u6027\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff08BDNF\uff09\uff0c\u4fdd\u62a4\u6b8b\u5b58\u795e\u7ecf\u5143\u5e76\u589e\u5f3a\u7a81\u89e6\u53ef\u5851\u6027\uff1b<\/li>\n<li><strong>\u514d\u75ab\u8c03\u63a7\uff1a<\/strong>\u8c03\u8282\u5c0f\u80f6\u8d28\u7ec6\u80de\u6d3b\u6027\uff0c\u6291\u5236\u795e\u7ecf\u708e\u75c7\u5fae\u73af\u5883\uff0c\u5ef6\u7f13\u03b1-\u7a81\u89e6\u6838\u86cb\u767d\u75c5\u7406\u8fdb\u5c55\u3002<\/li>\n<\/ul>\n<p>\u6700\u65b0\u4e34\u5e8a\u7814\u7a76\u8bc1\u5b9e\uff0c\u7ecf\u57fa\u56e0\u7f16\u8f91\u4f18\u5316\u7684\u81ea\u4f53iPSC-NSC\u79fb\u690d\u53ef\u4f7f\u60a3\u8005\u7edf\u4e00\u5e15\u91d1\u68ee\u75c5\u8bc4\u5b9a\u91cf\u8868\uff08UPDRS\uff09\u8bc4\u5206\u6539\u558440%-60%\uff0c\u4e14PET\u663e\u50cf\u663e\u793a\u79fb\u690d\u533a\u591a\u5df4\u80fa\u4ee3\u8c22\u6d3b\u6027\u6062\u590d\u81f3\u6b63\u5e38\u6c34\u5e73\u768470%\u4ee5\u4e0a\u3002\u672a\u6765\u9700\u7a81\u7834\u79fb\u690d\u7ec6\u80de\u957f\u671f\u5b58\u6d3b\u7387\uff08\uff1e6\u4e2a\u6708\uff09\u53ca\u529f\u80fd\u6574\u5408\u6548\u7387\u7b49\u74f6\u9888\uff0c\u4ee5\u5b9e\u73b0\u4ece\u75c7\u72b6\u63a7\u5236\u5411\u75be\u75c5\u4fee\u9970\u7684\u8de8\u8d8a\u3002<\/p>\n<p><strong>2. 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(ALS) \u65e0\u6cd5\u6cbb\u6108\uff0c\u4f46\u5e72\u7ec6\u80de\u7814\u7a76\u4e3a\u5f00\u53d1\u5bf9\u6297\u8be5\u75be\u75c5\u7684\u65b0\u7597\u6cd5\u548c\u518d\u751f\u7b56\u7565\u5e26\u6765\u4e86\u5e0c\u671b\u3002<\/p>\n<p><strong>5.\u810a\u9ad3\u635f\u4f24\u4e2d\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\uff1a<\/strong>\u810a\u9ad3\u635f\u4f24\u662f\u4e16\u754c\u4e0a\u6700\u5371\u9669\u7684\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u4e4b\u4e00\u3002\u7531\u4e8e\u810a\u9ad3\u635f\u4f24\u7684\u53d1\u751f\u7387\u5f88\u9ad8\uff0c\u7ed9\u793e\u4f1a\u5e26\u6765\u4e86\u6c89\u91cd\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002\u5c3d\u7ba1\u76ee\u524d\u7f3a\u4e4f\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\uff0c\u4f46\u795e\u7ecf\u5e72\u7ec6\u80de\u751f\u7269\u5b66\u7684\u6700\u65b0\u8fdb\u5c55\u4e3a\u5229\u7528\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u66ff\u4ee3\u5404\u79cd\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u4e2d\u4e22\u5931\u7684\u8111\u7ec6\u80de\u7684\u6cbb\u7597\u65b9\u6cd5\u521b\u9020\u4e86\u65b0\u7684\u673a\u4f1a\u3002<\/p>\n<p>\u795e\u7ecf\u7956\u7ec6\u80de\u79fb\u690d\u4e3a\u810a\u9ad3\u635f\u4f24\u7684\u518d\u751f\u548c\u4fee\u590d\u5e26\u6765\u4e86\u5de8\u5927\u7684\u5e0c\u671b\u3002<strong>\u591a\u79cd\u7ec6\u80de\u7c7b\u578b\uff0c\u5305\u62ec\u57fa\u56e0\u5de5\u7a0b\u6210\u7ea4\u7ef4\u7ec6\u80de\u3001\u55c5\u9798\u7ec6\u80de\u548c\u795e\u7ecf\u5e72\u7ec6\u80de\uff0c\u5df2\u88ab\u7528\u4e8e\u4fc3\u8fdb\u810a\u9ad3\u635f\u4f24\u7684\u8f74\u7a81\u518d\u751f<\/strong>The<\/p>\n<p><strong>6.\u591a\u53d1\u6027\u786c\u5316\u75c7\u4e2d\u7684\u795e\u7ecf\u5e72\u7ec6\u80de\uff1a<\/strong>\u5168\u7403\u6570\u767e\u4e07\u4eba\u60a3\u6709\u591a\u53d1\u6027\u786c\u5316\u75c7\uff0c\u8fd9\u662f\u4e00\u79cd\u957f\u671f\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002\u591a\u53d1\u6027\u786c\u5316\u75c7\u4f1a\u635f\u4f24\u5305\u88f9\u795e\u7ecf\u7ea4\u7ef4\u7684\u9ad3\u9798\uff0c\u5bfc\u81f4\u808c\u8089\u65e0\u529b\u3001\u50f5\u786c\u548c\u89c6\u529b\u969c\u788d\u7b49\u591a\u79cd\u75c7\u72b6\u3002\u5c3d\u7ba1\u591a\u53d1\u6027\u786c\u5316\u75c7\u7684\u6cbb\u7597\u65b9\u6cd5\u53d6\u5f97\u4e86\u5de8\u5927\u8fdb\u6b65\uff0c\u4f46\u76ee\u524d\u4ecd\u65e0\u6cd5\u6cbb\u6108\u8be5\u75c5\u3002<\/p>\n<p>\u8fc4\u4eca\u4e3a\u6b62\uff0c<strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u5df2\u6210\u4e3a\u4e00\u79cd\u6709\u5e0c\u671b\u7684\u66ff\u4ee3\u7597\u6cd5\u3002\u5229\u7528\u5e72\u7ec6\u80de\u56fa\u6709\u7684\u4fee\u590d\u548c\u518d\u751f\u6f5c\u529b<\/strong>\uff0c\u4e34\u5e8a\u4e0a\u6210\u529f\u7684\u591a\u53d1\u6027\u786c\u5316\u75c7\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u53ef\u80fd\u6807\u5fd7\u7740\u518d\u751f\u795e\u7ecf\u75c5\u5b66\u9886\u57df\u7684\u91cd\u5927\u8fdb\u6b65\uff0c\u5e76\u63d0\u4f9b\u4e00\u79cd\u65b0\u7684\u6cbb\u7597\u9009\u62e9\u3002\u88683\u603b\u7ed3\u4e86\u6574\u4f53\u7ec6\u8282\uff0c\u5e76\u5217\u51fa\u4e86\u4e00\u4e9b\u5173\u4e8e\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u6cbb\u7597\u5404\u79cd\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\u62a5\u544a\u3002<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div style=\"width: 1155px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/09\/20250924201741-68d3e165b029a.jpg\" alt=\"\u88683\uff1a\u7814\u7a76\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u5173\u952e\u6280\u672f\u53ca\u5176\u5728\u4eba\u7c7b\u7814\u7a76\u4e2d\u7684\u5e94\u7528\uff1a\u4e3b\u8981\u53d1\u73b0\u3002\" width=\"1145\" height=\"457\" title=\"\"><p class=\"wp-caption-text\">\u88683\uff1a\u7814\u7a76\u6210\u4eba\u795e\u7ecf\u53d1\u751f\u7684\u5173\u952e\u6280\u672f\u53ca\u5176\u5728\u4eba\u7c7b\u7814\u7a76\u4e2d\u7684\u5e94\u7528\uff1a\u4e3b\u8981\u53d1\u73b0\u3002<\/p><\/div><figcaption><\/figcaption><\/figure>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u6838\u5fc3\u4ef7\u503c\uff1a\u516d\u5927\u75be\u75c5\u5e94\u7528\u8bc1\u5b9e\u795e\u7ecf\u5e72\u7ec6\u80de\u5177\u5907 \u201c\u4e09\u4f4d\u4e00\u4f53\u201d\u6cbb\u7597\u4f18\u52bf\u2014\u2014\u66ff\u4ee3\u4e22\u5931\u7ec6\u80de\u3001\u91cd\u5851\u795e\u7ecf\u56de\u8def\u3001\u8c03\u63a7\u75c5\u7406\u5fae\u73af\u5883\uff0c\u4e3a\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u63d0\u4f9b\u4ece\u75c7\u72b6\u63a7\u5236\u8f6c\u5411\u75c5\u7406\u4fee\u6b63\u7684\u6cbb\u6108\u6027\u7b56\u7565\u3002<\/p><\/blockquote>\n<h2 id=\"h-\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u6700\u65b0\u8fdb\u5c55\u548c\u65b0\u89c1\u89e3\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E7%9A%84%E6%9C%80%E6%96%B0%E8%BF%9B%E5%B1%95%E5%92%8C%E6%96%B0%E8%A7%81%E8%A7%A3\"><\/span><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u7684\u6700\u65b0\u8fdb\u5c55\u548c\u65b0\u89c1\u89e3<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u795e\u7ecf\u5e72\u7ec6\u80de (NSC) \u6cbb\u7597\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u9610\u660e\u4e86\u8d85\u8d8a\u4f20\u7edf\u7ec6\u80de\u66ff\u4ee3\u7b56\u7565\u7684\u6cbb\u7597\u673a\u5236\uff0c\u4ece\u800c\u5f7b\u5e95\u6539\u53d8\u4e86\u518d\u751f\u533b\u5b66\u7684\u8303\u5f0f\u3002<\/p>\n<h3 id=\"h-1-\u6cbb\u7597\u673a\u5236\u7684\u8303\u5f0f\u9769\u65b0\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1%E3%80%81%E6%B2%BB%E7%96%97%E6%9C%BA%E5%88%B6%E7%9A%84%E8%8C%83%E5%BC%8F%E9%9D%A9%E6%96%B0\"><\/span><strong>1\u3001\u6cbb\u7597\u673a\u5236\u7684\u8303\u5f0f\u9769\u65b0<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<h3 id=\"h-\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u5df2\u7a81\u7834\u4f20\u7edf\u7ec6\u80de\u66ff\u4ee3\u7b56\u7565\u7684\u5c40\u9650-\u63ed\u793a\u5176\u901a\u8fc7-\u65c1\u89c2\u8005\u6548\u5e94-\u53d1\u6325\u591a\u7ef4\u5ea6\u6cbb\u7597\u4f5c\u7528\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E5%B7%B2%E7%AA%81%E7%A0%B4%E4%BC%A0%E7%BB%9F%E7%BB%86%E8%83%9E%E6%9B%BF%E4%BB%A3%E7%AD%96%E7%95%A5%E7%9A%84%E5%B1%80%E9%99%90%EF%BC%8C%E6%8F%AD%E7%A4%BA%E5%85%B6%E9%80%9A%E8%BF%87%E2%80%9D%E6%97%81%E8%A7%82%E8%80%85%E6%95%88%E5%BA%94%E2%80%9D%E5%8F%91%E6%8C%A5%E5%A4%9A%E7%BB%B4%E5%BA%A6%E6%B2%BB%E7%96%97%E4%BD%9C%E7%94%A8%EF%BC%9B\"><\/span><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u5df2\u7a81\u7834\u4f20\u7edf\u7ec6\u80de\u66ff\u4ee3\u7b56\u7565\u7684\u5c40\u9650\uff0c\u63ed\u793a\u5176\u901a\u8fc7\u201d\u65c1\u89c2\u8005\u6548\u5e94\u201d\u53d1\u6325\u591a\u7ef4\u5ea6\u6cbb\u7597\u4f5c\u7528\uff1b<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<ul class=\"wp-block-list\">\n<li>\u5206\u6ccc\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff08\u5982BDNF\u3001GDNF\uff09\u76f4\u63a5\u4fc3\u8fdb\u795e\u7ecf\u5143\u5b58\u6d3b\u3001\u7a81\u89e6\u53ef\u5851\u6027\u53ca\u795e\u7ecf\u518d\u751f\uff1b<\/li>\n<li>\u8c03\u63a7\u661f\u5f62\u80f6\u8d28\u7ec6\u80de\/\u5c0f\u80f6\u8d28\u6d3b\u6027\uff0c\u91cd\u5851\u795e\u7ecf\u514d\u75ab\u5fae\u73af\u5883\u4ee5\u51cf\u7f13\u75be\u75c5\u8fdb\u5c55\uff1b<\/li>\n<li>\u901a\u8fc7\u795e\u7ecf\u4fdd\u62a4\u4e0e\u514d\u75ab\u8c03\u8282\u53cc\u8def\u5f84\uff0c\u663e\u8457\u63d0\u5347\u5bf9\u6025\u6027\u635f\u4f24\uff08\u5352\u4e2d\uff09\u548c\u6162\u6027\u9000\u884c\u6027\u75be\u75c5\uff08\u5982\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff09\u7684\u6cbb\u7597\u6548\u80fd\u3002<\/li>\n<\/ul>\n<p>\u8fd9\u4e00\u673a\u5236\u9769\u65b0\u4f7fNSC\u4ece\u5355\u7eaf\u7684\u201d\u7ec6\u80de\u66ff\u4ee3\u5de5\u5177\u201d\u5347\u7ea7\u4e3a\u591a\u529f\u80fd\u751f\u7269\u8c03\u8282\u5e73\u53f0\u3002<\/p>\n<h3 id=\"h-2-\u7ec6\u80de\u6765\u6e90\u4e0e\u4e34\u5e8a\u8f6c\u5316\u7a81\u7834-\u6765\u6e90\u521b\u65b0\u5927\u5e45\u63a8\u52a8\u4e34\u5e8a\u8f6c\u5316\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2%E3%80%81%E7%BB%86%E8%83%9E%E6%9D%A5%E6%BA%90%E4%B8%8E%E4%B8%B4%E5%BA%8A%E8%BD%AC%E5%8C%96%E7%AA%81%E7%A0%B4%EF%BC%9A%E6%9D%A5%E6%BA%90%E5%88%9B%E6%96%B0%E5%A4%A7%E5%B9%85%E6%8E%A8%E5%8A%A8%E4%B8%B4%E5%BA%8A%E8%BD%AC%E5%8C%96\"><\/span><strong>2\u3001\u7ec6\u80de\u6765\u6e90\u4e0e\u4e34\u5e8a\u8f6c\u5316\u7a81\u7834\uff1a\u6765\u6e90\u521b\u65b0\u5927\u5e45\u63a8\u52a8\u4e34\u5e8a\u8f6c\u5316<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<ul class=\"wp-block-list\">\n<li>\u4f26\u7406\u4f18\u5316\uff1a\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\u5206\u5316\u6280\u672f\u66ff\u4ee3\u80da\u80ce\u5e72\u7ec6\u80de\uff0c\u89c4\u907f\u4f26\u7406\u4e89\u8bae\uff1b<\/li>\n<li>\u5fae\u521b\u83b7\u53d6\uff1a\u8111\u810a\u6db2\uff08CSF\uff09\u5206\u79bbNSC\u5b9e\u73b0\u5fae\u521b\u5316\u7ec6\u80de\u91c7\u96c6\uff1b<\/li>\n<li>\u7cbe\u51c6\u9012\u9001\uff1a\u5229\u7528NSC\u5929\u7136\u80bf\u7624\u8d8b\u5411\u6027\uff0c\u88c5\u8f7d\u7ec6\u80de\u6bd2\u6027\u836f\u7269\u9776\u5411\u8111\u80bf\u7624\u3002<\/li>\n<\/ul>\n<p>\u5e94\u7528\u62d3\u5c55\u8986\u76d6\u591a\u9886\u57df\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li>\u795e\u7ecf\u75be\u75c5\uff1a\u4fee\u590d\u5352\u4e2d\u540e\u795e\u7ecf\u56de\u8def\uff0c\u6539\u5584\u8fd0\u52a8\u529f\u80fd\uff1b<\/li>\n<li>\u80bf\u7624\u6cbb\u7597\uff1a\u4f5c\u4e3a\u201d\u6d3b\u4f53\u8f7d\u836f\u7cfb\u7edf\u201d\u7cbe\u51c6\u6740\u4f24\u80f6\u8d28\u7624\uff1b<\/li>\n<li>\u4e2a\u4f53\u5316\u533b\u7597\uff1a\u60a3\u8005\u7279\u5f02\u6027iPSC-NSC\u964d\u4f4e\u514d\u75ab\u6392\u65a5\u98ce\u9669\u3002<\/li>\n<\/ul>\n<h3 id=\"h-3-\u6280\u672f\u878d\u5408\u9a71\u52a8\u7cbe\u51c6\u6cbb\u7597-\u57fa\u56e0\u5de5\u7a0b\u4e0e\u6210\u50cf\u6280\u672f\u8d4b\u80fd\u6cbb\u7597\u5347\u7ea7\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3%E3%80%81%E6%8A%80%E6%9C%AF%E8%9E%8D%E5%90%88%E9%A9%B1%E5%8A%A8%E7%B2%BE%E5%87%86%E6%B2%BB%E7%96%97%EF%BC%9A%E5%9F%BA%E5%9B%A0%E5%B7%A5%E7%A8%8B%E4%B8%8E%E6%88%90%E5%83%8F%E6%8A%80%E6%9C%AF%E8%B5%8B%E8%83%BD%E6%B2%BB%E7%96%97%E5%8D%87%E7%BA%A7\"><\/span><strong>3\u3001\u6280\u672f\u878d\u5408\u9a71\u52a8\u7cbe\u51c6\u6cbb\u7597\uff1a\u57fa\u56e0\u5de5\u7a0b\u4e0e\u6210\u50cf\u6280\u672f\u8d4b\u80fd\u6cbb\u7597\u5347\u7ea7<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<ul class=\"wp-block-list\">\n<li>CRISPR-Cas9\u6539\u9020\uff1a\u7f16\u8f91NSC\u8fc7\u8868\u8fbe\u6cbb\u7597\u6027\u57fa\u56e0\uff0c\u589e\u5f3a\u795e\u7ecf\u4fdd\u62a4\/\u514d\u75ab\u8c03\u8282\u529f\u80fd\uff1b<\/li>\n<li>\u5206\u6ccc\u7ec4\u7597\u6cd5\uff1a\u7eaf\u5316NSC\u5206\u6ccc\u56e0\u5b50\uff08\u5982\u5916\u6ccc\u4f53\uff09\u4f5c\u4e3a\u65e0\u7ec6\u80de\u6cbb\u7597\u65b0\u7b56\u7565\uff1b<\/li>\n<li>\u5b9e\u65f6\u8ffd\u8e2a\uff1aMRI\/\u8367\u5149\u6210\u50cf\u52a8\u6001\u76d1\u6d4bNSC\u8111\u5185\u8fc1\u79fb\u4e0e\u6574\u5408\uff0c\u4f18\u5316\u6cbb\u7597\u65b9\u6848\u3002<\/li>\n<\/ul>\n<p>\u8fd9\u4e9b\u6280\u672f\u534f\u540c\u63a8\u52a8NSC\u7597\u6cd5\u5411\u53ef\u76d1\u6d4b\u3001\u53ef\u8c03\u63a7\u3001\u4e2a\u6027\u5316\u7684\u4e0b\u4e00\u4ee3\u6cbb\u7597\u4f53\u7cfb\u6f14\u8fdb\uff08\u8be6\u89c1\u88683\u4e34\u5e8a\u8f6c\u5316\u8def\u7ebf\uff09\u3002<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u6838\u5fc3\u8fdb\u5c55\u603b\u7ed3\uff1a\u4ece\u201d\u66ff\u4ee3\u795e\u7ecf\u5143\u201d\u5230\u201d\u591a\u529f\u80fd\u751f\u7269\u8c03\u8282\u5668\u201d\u7684\u8ba4\u77e5\u8dc3\u8fc1\u2192\u6765\u6e90\u521b\u65b0\u89e3\u51b3\u4f26\u7406\u4e0e\u514d\u75ab\u74f6\u9888 \u2192 \u57fa\u56e0\u7f16\u8f91\/\u6210\u50cf\u6280\u672f\u5b9e\u73b0\u7cbe\u51c6\u53ef\u63a7\u6cbb\u7597\u2192\u8986\u76d6\u795e\u7ecf\u4fee\u590d\u4e0e\u80bf\u7624\u9776\u5411\u7684\u53cc\u91cd\u5e94\u7528\u573a\u666f \u2192 \u5960\u5b9a\u4e2a\u6027\u5316\u518d\u751f\u533b\u5b66\u65b0\u8303\u5f0f\u3002<\/p><\/blockquote>\n<h2 id=\"h-\u795e\u7ecf\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u524d\u666f\u548c\u672a\u6765\u65b9\u5411\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E7%A5%9E%E7%BB%8F%E9%80%80%E8%A1%8C%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E5%89%8D%E6%99%AF%E5%92%8C%E6%9C%AA%E6%9D%A5%E6%96%B9%E5%90%91\"><\/span><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u524d\u666f\u548c\u672a\u6765\u65b9\u5411<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u795e\u7ecf\u5e72\u7ec6\u80de (NSC) \u7597\u6cd5\u5df2\u6210\u4e3a\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u548c\u8111\u635f\u4f24\u7684\u4e00\u79cd\u6781\u5177\u524d\u666f\u7684\u65b9\u6cd5\uff0c\u5728\u4e34\u5e8a\u524d\u548c\u521d\u6b65\u4e34\u5e8a\u7814\u7a76\u4e2d\u5747\u5c55\u73b0\u51fa\u6f5c\u5728\u7684\u7597\u6548\u3002<\/p>\n<h3 id=\"h-1-\u4e09\u5927\u6280\u672f\u7a81\u7834\u5960\u5b9a\u4e34\u5e8a\u8f6c\u5316\u57fa\u77f3\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_%E4%B8%89%E5%A4%A7%E6%8A%80%E6%9C%AF%E7%AA%81%E7%A0%B4%E5%A5%A0%E5%AE%9A%E4%B8%B4%E5%BA%8A%E8%BD%AC%E5%8C%96%E5%9F%BA%E7%9F%B3\"><\/span><strong>1. \u4e09\u5927\u6280\u672f\u7a81\u7834\u5960\u5b9a\u4e34\u5e8a\u8f6c\u5316\u57fa\u77f3<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u5728\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u53ca\u8111\u635f\u4f24\u9886\u57df\u5c55\u73b0\u51fa\u9769\u547d\u6027\u6f5c\u529b\uff0c\u5176\u6280\u672f\u751f\u6001\u5df2\u5b9e\u73b0\u4e09\u5927\u8dc3\u5347\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u63d0\u53d6\u6280\u672f\u53d6\u5f97\u663e\u8457\u8fdb\u5c55\u4f7f\u7ec6\u80de\u6765\u6e90\u591a\u5143\u5316\uff1a<\/strong>\u4ece\u8111\u7ec4\u7ec7\u76f4\u63a5\u5206\u79bb\u3001\u591a\u80fd\u5e72\u7ec6\u80de\uff08\u542biPSC\uff09\u5206\u5316\u5230\u4f53\u7ec6\u80de\u8f6c\u5206\u5316\u6280\u672f\u6210\u719f\u5316\uff1b<\/li>\n<li><strong>\u529f\u80fd\u5f3a\u5316\uff1a<\/strong>CRISPR-Cas9\u57fa\u56e0\u7f16\u8f91\u7cbe\u51c6\u589e\u5f3aNSC\u795e\u7ecf\u4fdd\u62a4\u4e0e\u514d\u75ab\u8c03\u8282\u80fd\u529b\uff1b<\/li>\n<li><strong>\u8fc7\u7a0b\u53ef\u63a7\u5316\uff1a<\/strong>\u795e\u7ecf\u8c03\u63a7\u7b56\u7565\u5f15\u5bfc\u5206\u5316\/\u8fc1\u79fb\uff0c\u975e\u4fb5\u5165\u6210\u50cf\u5b9e\u65f6\u76d1\u6d4b\u7ec6\u80de\u6574\u5408\uff08\u5982MRI\u8ffd\u8e2a\u79fb\u690d\u7ec6\u80de\u52a8\u6001\uff09\u3002<\/li>\n<\/ul>\n<p>\u8fd9\u4e9b\u7a81\u7834\u4e3a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3001\u5e15\u91d1\u68ee\u75c5\u7b49\u75be\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\u63d0\u4f9b\u4e86\u575a\u5b9e\u652f\u6491\u3002<\/p>\n<h3 id=\"h-2-\u73b0\u9636\u6bb5\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6280\u672f\u7684\u6311\u6218\u4e0e\u8f6c\u5316\u74f6\u9888\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_%E7%8E%B0%E9%98%B6%E6%AE%B5%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%8A%80%E6%9C%AF%E7%9A%84%E6%8C%91%E6%88%98%E4%B8%8E%E8%BD%AC%E5%8C%96%E7%93%B6%E9%A2%88\"><\/span><strong>2. \u73b0\u9636\u6bb5\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6280\u672f\u7684\u6311\u6218\u4e0e\u8f6c\u5316\u74f6\u9888<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u5c3d\u7ba1\u53d6\u5f97\u4e86\u8fd9\u4e9b\u8fdb\u5c55\uff0c\u4f46\u4ecd\u5b58\u5728\u8bb8\u591a\u6311\u6218\uff0c\u963b\u788d\u7740NSC\u7597\u6cd5\u5728\u4e34\u5e8a\u4e0a\u7684\u5e7f\u6cdb\u5b9e\u65bd\uff0c\u5982\u4e0b\u6240\u6709\u793a\uff1a<\/p>\n<figure class=\"wp-block-table is-style-stripes\">\n<table class=\"has-fixed-layout\">\n<thead>\n<tr>\n<th><strong>\u6838\u5fc3\u6311\u6218<\/strong><\/th>\n<th><strong>\u5177\u4f53\u969c\u788d<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>\u7597\u6548\u4e00\u81f4\u6027<\/strong><\/td>\n<td>\u4e34\u5e8a\u524d\u7ed3\u679c\u96be\u4ee5\u590d\u73b0\u81f3\u4eba\u4f53\uff0c\u673a\u5236\u590d\u6742\u6027\uff08\u5982\u5352\u4e2d\u540e\u5fae\u73af\u5883\uff09\u5bfc\u81f4\u7597\u6548\u5dee\u5f02<\/td>\n<\/tr>\n<tr>\n<td><strong>\u5b89\u5168\u6027\u98ce\u9669<\/strong><\/td>\n<td>\u81f4\u7624\u6027\uff08\u5c24\u5176\u591a\u80fd\u5e72\u7ec6\u80de\u6765\u6e90\uff09\u3001\u514d\u75ab\u6392\u65a5\u3001\u57fa\u56e0\u7f16\u8f91\u8131\u9776\u6548\u5e94\u9700\u7ec8\u8eab\u76d1\u6d4b<\/td>\n<\/tr>\n<tr>\n<td><strong>\u9012\u9001\u6548\u7387<\/strong><\/td>\n<td>\u975e\u4fb5\u5165\u9012\u9001\uff08\u9f3b\u8154\/CSF\uff09\u53d7\u8840\u8111\u5c4f\u969c\u963b\u9694\uff0c\u7ec6\u80de\u5b58\u6d3b\u7387&lt;30%\uff1b\u4fb5\u5165\u5f0f\u624b\u672f\u5e76\u53d1\u75c7\u7387\u9ad8<\/td>\n<\/tr>\n<tr>\n<td><strong>\u4f26\u7406\u4e89\u8bae<\/strong><\/td>\n<td>\u80da\u80ce\u5e72\u7ec6\u80de\u5e94\u7528\u53ca\u57fa\u56e0\u6539\u9020\u7684\u4f26\u7406\u56f0\u5883\u5ef6\u7f13\u4e34\u5e8a\u8fdb\u7a0b<\/td>\n<\/tr>\n<tr>\n<td><strong>\u6574\u5408\u6548\u80fd<\/strong><\/td>\n<td>\u79fb\u690d\u7ec6\u80de\u957f\u671f\u5b58\u6d3b\u7387\u4f4e\uff08&lt;15%\uff09\uff0c\u795e\u7ecf\u56de\u8def\u529f\u80fd\u6574\u5408\u4e0d\u8db3<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<h3 id=\"h-3-\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6280\u672f\u672a\u6765\u7a81\u7834\u7684\u6838\u5fc3\u65b9\u5411\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%8A%80%E6%9C%AF%E6%9C%AA%E6%9D%A5%E7%AA%81%E7%A0%B4%E7%9A%84%E6%A0%B8%E5%BF%83%E6%96%B9%E5%90%91\"><\/span><strong>3. \u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6280\u672f\u672a\u6765\u7a81\u7834\u7684\u6838\u5fc3\u65b9\u5411<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<h3 id=\"h-\u795e\u7ecf\u5e72\u7ec6\u80de\u6280\u672f\u4f18\u5316\u5c42\u9762\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E6%8A%80%E6%9C%AF%E4%BC%98%E5%8C%96%E5%B1%82%E9%9D%A2%EF%BC%9A\"><\/span><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u6280\u672f\u4f18\u5316\u5c42\u9762<\/strong>::<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<ul class=\"wp-block-list\">\n<li>\u5efa\u7acb\u6807\u51c6\u5316\u8d28\u63a7\u4f53\u7cfb\uff1a\u7edf\u4e00NSC\u5206\u79bb\u3001\u8868\u5f81\u4e0e\u79fb\u690d\u6d41\u7a0b\uff0c\u51cf\u5c11\u4e34\u5e8a\u53d8\u5f02\uff1b<\/li>\n<li>\u5f00\u53d1\u4eff\u751f\u5fae\u73af\u5883\u652f\u67b6\uff1a\u751f\u7269\u6750\u6599\u8d1f\u8f7d\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff0c\u63d0\u5347\u79fb\u690d\u7ec6\u80de\u5b58\u6d3b\u7387\u81f3&gt;60%\uff1b<\/li>\n<li>\u63a8\u8fdb\u4e2a\u4f53\u5316iPSC-NSC\u7597\u6cd5\uff1a\u60a3\u8005\u7279\u5f02\u6027\u7ec6\u80de\u5e93\u89c4\u907f\u514d\u75ab\u6392\u65a5\uff0c\u57fa\u56e0\u7f16\u8f91\u5b9a\u5236\u6cbb\u7597\u86cb\u767d\u8868\u8fbe\u3002<\/li>\n<\/ul>\n<p><strong>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u5b89\u5168\u62a4\u822a\u5c42\u9762<\/strong>::<\/p>\n<ul class=\"wp-block-list\">\n<li>\u6784\u5efa\u8868\u89c2\u9057\u4f20\u7a33\u5b9a\u6027\u7b5b\u9009\u5e73\u53f0\uff0c\u6d88\u9664\u81f4\u7624\u98ce\u9669\uff1b<\/li>\n<li>\u5efa\u7acb15\u5e74\u4ee5\u4e0a\u957f\u671f\u5b89\u5168\u8ffd\u8e2a\u6570\u636e\u5e93\u3002<\/li>\n<\/ul>\n<h3 id=\"h-4-\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u98a0\u8986\u6027\u6280\u672f\u878d\u5408\u8def\u5f84\" class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"4_%E7%A5%9E%E7%BB%8F%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E9%A2%A0%E8%A6%86%E6%80%A7%E6%8A%80%E6%9C%AF%E8%9E%8D%E5%90%88%E8%B7%AF%E5%BE%84\"><\/span><strong>4. \u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u98a0\u8986\u6027\u6280\u672f\u878d\u5408\u8def\u5f84<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<ul class=\"wp-block-list\">\n<li><strong>\u57fa\u56e0\u7f16\u8f912.0\uff1a<\/strong>CRISPR-Cas9\u5347\u7ea7\u7248\uff08\u5982\u78b1\u57fa\u7f16\u8f91\uff09\u7cbe\u51c6\u8c03\u63a7BDNF\/GDNF\u8868\u8fbe\uff0c\u89c4\u907f\u8131\u9776\u98ce\u9669\uff1b<\/li>\n<li><strong>\u667a\u80fd\u9012\u9001\u7cfb\u7edf\uff1a<\/strong>\u7eb3\u7c73\u8f7d\u4f53\u4fee\u9970NSC\u7a7f\u900f\u8840\u8111\u5c4f\u969c\uff0c\u9776\u5411\u635f\u4f24\u533a\u91ca\u653e\u7387\u8fbe90%\uff1b<\/li>\n<li><strong>\u65e0\u7ec6\u80de\u6cbb\u7597\u65b0\u8303\u5f0f\uff1a<\/strong>NSC\u5206\u6ccc\u7ec4\uff08\u5916\u6ccc\u4f53\/\u6d3b\u6027\u56e0\u5b50\uff09\u4f5c\u4e3a\u201d\u73b0\u6210\u7597\u6cd5\u201d\uff0c\u89c4\u907f\u7ec6\u80de\u79fb\u690d\u98ce\u9669\uff1b<\/li>\n<li><strong>\u6570\u5b57\u5b6a\u751f\u6a21\u578b\uff1a<\/strong>AI\u6a21\u62df\u60a3\u8005\u8111\u5185NSC\u6574\u5408\u8def\u5f84\uff0c\u4e2a\u6027\u5316\u9884\u6d4b\u7597\u6548\u3002<\/li>\n<\/ul>\n<p><strong>\u5199\u5728\u6700\u540e\uff1a<\/strong>\u603b\u800c\u8a00\u4e4b\uff0c\u5c3d\u7ba1NSC\u7597\u6cd5\u5728\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u6cbb\u7597\u4e2d\u5c55\u73b0\u51fa\u5de8\u5927\u7684\u6f5c\u529b\uff0c\u4f46\u514b\u670d\u5b89\u5168\u6027\u3001\u7ed9\u836f\u9014\u5f84\u548c\u4e34\u5e8a\u591a\u53d8\u6027\u7b49\u6311\u6218\u5bf9\u4e8e\u5176\u66f4\u5e7f\u6cdb\u7684\u4e34\u5e8a\u5e94\u7528\u81f3\u5173\u91cd\u8981\u3002<\/p>\n<p>\u6301\u7eed\u5f00\u5c55\u7814\u7a76\uff0c\u4ee5\u6539\u8fdbNSC\u63d0\u53d6\u6280\u672f\u3001\u589e\u5f3a\u7ec6\u80de\u5b58\u6d3b\u548c\u6574\u5408\u80fd\u529b\u4ee5\u53ca\u89e3\u51b3\u5b89\u5168\u6027\u95ee\u9898\uff0c\u5bf9\u4e8e\u5145\u5206\u53d1\u6325NSC\u5e72\u9884\u63aa\u65bd\u7684\u6cbb\u7597\u6f5c\u529b\u81f3\u5173\u91cd\u8981\u3002\u901a\u8fc7\u6301\u7eed\u521b\u65b0\u548c\u8de8\u5b66\u79d1\u5408\u4f5c\uff0c\u795e\u7ecf\u5e72\u7ec6\u80de\u7597\u6cd5\u6700\u7ec8\u6709\u671b\u4e3a\u5404\u79cd\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u63d0\u4f9b\u6709\u6548\u3001\u5b89\u5168\u4e14\u4fbf\u6377\u7684\u6cbb\u7597\u9009\u62e9\u3002<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u53c2\u8003\u8d44\u6599:[1]:Bayleyegn Derso T, Mengistu BA, Demessie Y, Fenta MD and Getnet K (2025) Neural stem cells in adult neurogenesis and their therapeutic applications in neurodegenerative disorders: a concise review.\u00a0<em>Front. Mol. Med.<\/em>\u00a05:1569717. doi: 10.3389\/fmmed.2025.1569717<\/p><\/blockquote>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>Disclaimer: This article is intended only to disseminate scientific knowledge and share industry perspectives, and does not constitute any clinical diagnostic advice! The information published by Hangi Stem Cells is not a substitute for the professional advice of a physician or pharmacist. If you have any questions about copyright or other issues, please feel free to contact me.<\/p><\/blockquote>","protected":false},"excerpt":{"rendered":"<p>\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u6b63\u6210\u4e3a\u5168\u7403\u518d\u751f\u533b\u5b66\u7814\u7a76\u7684\u70ed\u70b9\u3002\u672c\u6587\u6df1\u5165\u89e3\u6790\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3001\u5e15\u91d1\u68ee\u75c5\u3001\u4e2d\u98ce\u3001\u810a\u9ad3\u635f\u4f24\u3001\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\u53ca\u591a\u53d1\u6027\u786c\u5316\u75c7\u7b49\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u4e2d\u7684\u4f5c\u7528\u673a\u5236\u4e0e\u6700\u65b0\u8fdb\u5c55\uff0c\u63a2\u8ba8\u5176\u901a\u8fc7\u7ec6\u80de\u66ff\u4ee3\u3001\u795e\u7ecf\u8425\u517b\u4e0e\u514d\u75ab\u8c03\u63a7\u5b9e\u73b0\u795e\u7ecf\u529f\u80fd\u4fee\u590d\u7684\u6f5c\u529b\u3002\u5168\u9762\u4e86\u89e3\u795e\u7ecf\u5e72\u7ec6\u80de\u79fb\u690d\u5982\u4f55\u4e3a\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u6cbb\u7597\u5e26\u6765\u65b0\u7684\u5e0c\u671b\u4e0e\u7a81\u7834\u3002<\/p>","protected":false},"author":1,"featured_media":19249,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":{"footnotes":""},"categories":[73],"tags":[169,164,168],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/19258"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/comments?post=19258"}],"version-history":[{"count":3,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/19258\/revisions"}],"predecessor-version":[{"id":19341,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/19258\/revisions\/19341"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media\/19249"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media?parent=19258"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/categories?post=19258"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/tags?post=19258"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}