{"id":19858,"date":"2025-10-22T14:40:11","date_gmt":"2025-10-22T06:40:11","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=19858"},"modified":"2025-10-22T15:18:08","modified_gmt":"2025-10-22T07:18:08","slug":"%e6%b2%bb%e7%96%97%e5%b8%95%e9%87%91%e6%a3%ae%e7%97%85%e7%9a%84%e8%8d%af%e7%89%a9%e6%9c%89%e5%93%aa%e5%87%a0%e7%a7%8d%ef%bc%9a%e4%bb%8e%e9%87%91%e6%a0%87%e5%87%86%e5%b7%a6%e6%97%8b","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html","title":{"rendered":"\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u836f\u7269\u6709\u54ea\u51e0\u79cd\uff1a\u4ece\u201c\u91d1\u6807\u51c6\u201d\u5de6\u65cb\u591a\u5df4\u5230\u591a\u7c7b\u9776\u5411\u836f\u7269\u201d"},"content":{"rendered":"<p data-start=\"191\" data-end=\"316\"><a href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19756.html\/\" target=\"_blank\" rel=\"noopener\">Parkinson's disease<\/a>\u662f\u4e00\u79cd\u5e38\u89c1\u7684\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff0c\u5176\u6838\u5fc3\u95ee\u9898\u662f<strong data-start=\"215\" data-end=\"233\">\u8111\u5185\u9ed1\u8d28\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u7684\u9000\u53d8<\/strong>\u3002\u7531\u4e8e\u591a\u5df4\u80fa\u6c34\u5e73\u4e0b\u964d\uff0c\u60a3\u8005\u51fa\u73b0\u9707\u98a4\u3001\u808c\u5f3a\u76f4\u3001\u52a8\u4f5c\u8fdf\u7f13\u3001\u6b65\u6001\u5f02\u5e38\u7b49\u75c7\u72b6\u3002\u76ee\u524d\uff0c\u5e15\u91d1\u68ee\u75c5\u4ecd\u65e0\u6cd5\u6839\u6cbb\uff0c\u4f46<strong data-start=\"285\" data-end=\"293\">\u836f\u7269\u6cbb\u7597<\/strong>\u53ef\u4ee5\u663e\u8457\u6539\u5584\u75c7\u72b6\u3001\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\uff0c\u63d0\u9ad8\u751f\u6d3b\u8d28\u91cf\u3002\u90a3\u4e48\uff0c\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u836f\u7269\u6709\u54ea\u51e0\u79cd\uff1f\u5b83\u4eec\u662f\u5982\u4f55\u8d77\u4f5c\u7528\u7684\uff1f\u4ec0\u4e48\u65f6\u5019\u7528\uff1f\u53c8\u6709\u54ea\u4e9b\u526f\u4f5c\u7528\u548c\u5e76\u53d1\u75c7\u9700\u8981\u6ce8\u610f\uff1f<\/p>\n<p data-start=\"318\" data-end=\"390\">\u672c\u6587\u5c06\u7cfb\u7edf\u68b3\u7406\u76ee\u524d\u4e34\u5e8a\u4f7f\u7528\u7684\u4e3b\u8981\u836f\u7269\u7c7b\u522b\u3002<\/p>\n<p data-start=\"318\" data-end=\"390\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-19848 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-894293166-612x612-1.jpg\" alt=\"\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u836f\u7269\u6709\u54ea\u51e0\u79cd\uff1a\u4ece\u201c\u91d1\u6807\u51c6\u201d\u5de6\u65cb\u591a\u5df4\u5230\u591a\u7c7b\u9776\u5411\u836f\u7269\u201d\" width=\"612\" height=\"408\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-894293166-612x612-1.jpg 612w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-894293166-612x612-1-300x200.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-894293166-612x612-1-18x12.jpg 18w\" sizes=\"(max-width: 612px) 100vw, 612px\" \/><\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#%E4%B8%80%E3%80%81_%E8%8D%AF%E7%89%A9%E6%B2%BB%E7%96%97%E7%9A%84%E6%A0%B8%E5%BF%83%E6%88%98%E7%95%A5%EF%BC%9A%E2%80%9C%E7%BC%BA%E4%BB%80%E4%B9%88%EF%BC%8C%E8%A1%A5%E4%BB%80%E4%B9%88%E2%80%9D\" >\u4e00\u3001 \u836f\u7269\u6cbb\u7597\u7684\u6838\u5fc3\u6218\u7565\uff1a\u201c\u7f3a\u4ec0\u4e48\uff0c\u8865\u4ec0\u4e48\u201d<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#%E4%BA%8C%E3%80%81_%E6%B2%BB%E7%96%97%E5%B8%95%E9%87%91%E6%A3%AE%E7%97%85%E7%9A%84%E8%8D%AF%E7%89%A9%E6%9C%89%E5%93%AA%E5%87%A0%E7%A7%8D%EF%BC%9F6%E5%A4%A7%E6%A0%B8%E5%BF%83%E8%8D%AF%E7%89%A9%E7%B1%BB%E5%88%AB%E8%AF%A6%E8%A7%A3\" >\u4e8c\u3001 \u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u836f\u7269\u6709\u54ea\u51e0\u79cd\uff1f6\u5927\u6838\u5fc3\u836f\u7269\u7c7b\u522b\u8be6\u89e3<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#%E6%B2%BB%E7%96%97%E5%B8%95%E9%87%91%E6%A3%AE%E7%97%85%E8%BF%90%E5%8A%A8%E7%97%87%E7%8A%B6%E7%9A%84%E8%8D%AF%E7%89%A9\" >\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u8fd0\u52a8\u75c7\u72b6\u7684\u836f\u7269<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#01%E3%80%81%E5%B7%A6%E6%97%8B%E5%A4%9A%E5%B7%B4%EF%BC%9A%E4%BB%8D%E7%84%B6%E6%98%AF%E5%B8%95%E9%87%91%E6%A3%AE%E6%B2%BB%E7%96%97%E7%9A%84%E2%80%9C%E9%87%91%E6%A0%87%E5%87%86%E2%80%9D\" >01\u3001\u5de6\u65cb\u591a\u5df4\uff1a\u4ecd\u7136\u662f\u5e15\u91d1\u68ee\u6cbb\u7597\u7684\u201c\u91d1\u6807\u51c6\u201d<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#02%E3%80%81%E5%A4%9A%E5%B7%B4%E8%83%BA%E5%8F%97%E4%BD%93%E6%BF%80%E5%8A%A8%E5%89%82%EF%BC%9A%E6%A8%A1%E4%BB%BF%E5%A4%9A%E5%B7%B4%E8%83%BA%E7%9A%84%E4%BD%9C%E7%94%A8\" >02\u3001\u591a\u5df4\u80fa\u53d7\u4f53\u6fc0\u52a8\u5242\uff1a\u6a21\u4eff\u591a\u5df4\u80fa\u7684\u4f5c\u7528<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#03%E3%80%81MAO-B%E6%8A%91%E5%88%B6%E5%89%82%EF%BC%9A%E5%BB%B6%E9%95%BF%E5%A4%9A%E5%B7%B4%E8%83%BA%E5%AF%BF%E5%91%BD%E7%9A%84%E2%80%9C%E8%BE%85%E5%8A%A9%E5%85%B5%E2%80%9D\" >03\u3001MAO-B\u6291\u5236\u5242\uff1a\u5ef6\u957f\u591a\u5df4\u80fa\u5bff\u547d\u7684\u201c\u8f85\u52a9\u5175\u201d<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#04%E3%80%81%E5%84%BF%E8%8C%B6%E9%85%9A-O-%E7%94%B2%E5%9F%BA%E8%BD%AC%E7%A7%BB%E9%85%B6%E6%8A%91%E5%88%B6%E5%89%82%EF%BC%88COMT%EF%BC%89%EF%BC%9A%E5%BB%B6%E9%95%BF%E5%B7%A6%E6%97%8B%E5%A4%9A%E5%B7%B4%E5%9C%A8%E4%BD%93%E5%86%85%E7%9A%84%E5%AF%BF%E5%91%BD\" >04\u3001\u513f\u8336\u915a-O-\u7532\u57fa\u8f6c\u79fb\u9176\u6291\u5236\u5242\uff08COMT\uff09\uff1a\u5ef6\u957f\u5de6\u65cb\u591a\u5df4\u5728\u4f53\u5185\u7684\u5bff\u547d<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#05%E3%80%81%E6%8A%97%E8%83%86%E7%A2%B1%E8%83%BD%E8%8D%AF%E7%89%A9%EF%BC%9A%E7%94%A8%E4%BA%8E%E9%9C%87%E9%A2%A4%E4%B8%BA%E4%B8%BB%E7%9A%84%E5%B9%B4%E8%BD%BB%E6%82%A3%E8%80%85\" >05\u3001\u6297\u80c6\u78b1\u80fd\u836f\u7269\uff1a\u7528\u4e8e\u9707\u98a4\u4e3a\u4e3b\u7684\u5e74\u8f7b\u60a3\u8005<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#06%E3%80%81%E9%87%91%E5%88%9A%E7%83%B7%E8%83%BA%EF%BC%88Amantadine%EF%BC%89%EF%BC%9A%E5%85%BC%E5%85%B7%E6%8A%97%E7%97%85%E6%AF%92%E4%B8%8E%E6%8A%97%E5%BC%82%E5%8A%A8%E4%BD%9C%E7%94%A8\" >06\u3001\u91d1\u521a\u70f7\u80fa\uff08Amantadine\uff09\uff1a\u517c\u5177\u6297\u75c5\u6bd2\u4e0e\u6297\u5f02\u52a8\u4f5c\u7528<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#%E4%B8%89%E3%80%81_%E9%95%BF%E6%9C%9F%E6%B2%BB%E7%96%97%E7%9A%84%E6%A0%B8%E5%BF%83%E6%8C%91%E6%88%98%EF%BC%9A%E8%BF%90%E5%8A%A8%E5%B9%B6%E5%8F%91%E7%97%87%E7%9A%84%E7%AE%A1%E7%90%86\" >\u4e09\u3001 \u957f\u671f\u6cbb\u7597\u7684\u6838\u5fc3\u6311\u6218\uff1a\u8fd0\u52a8\u5e76\u53d1\u75c7\u7684\u7ba1\u7406<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#1_%E5%89%82%E6%9C%AB%E7%8E%B0%E8%B1%A1%E2%80%94%E2%80%94%E8%8D%AF%E6%95%88%E2%80%9C%E6%96%AD%E7%94%B5%E2%80%9D\" >1. \u5242\u672b\u73b0\u8c61\u2014\u2014\u836f\u6548\u201c\u65ad\u7535\u201d<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#2_%E5%BC%82%E5%8A%A8%E7%97%87%E2%80%94%E2%80%94%E8%8D%AF%E6%95%88%E2%80%9C%E8%BF%87%E9%87%8F%E2%80%9D\" >2. \u5f02\u52a8\u75c7\u2014\u2014\u836f\u6548\u201c\u8fc7\u91cf\u201d<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hjtdsm.cn\/en\/research\/ns\/pd\/19858.html\/#%E6%80%BB%E7%BB%93%EF%BC%9A%E4%B8%AA%E4%BD%93%E5%8C%96%E7%94%A8%E8%8D%AF%E6%98%AF%E5%85%B3%E9%94%AE\" >\u603b\u7ed3\uff1a\u4e2a\u4f53\u5316\u7528\u836f\u662f\u5173\u952e<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%E4%B8%80%E3%80%81_%E8%8D%AF%E7%89%A9%E6%B2%BB%E7%96%97%E7%9A%84%E6%A0%B8%E5%BF%83%E6%88%98%E7%95%A5%EF%BC%9A%E2%80%9C%E7%BC%BA%E4%BB%80%E4%B9%88%EF%BC%8C%E8%A1%A5%E4%BB%80%E4%B9%88%E2%80%9D\"><\/span><strong>\u4e00\u3001 \u836f\u7269\u6cbb\u7597\u7684\u6838\u5fc3\u6218\u7565\uff1a\u201c\u7f3a\u4ec0\u4e48\uff0c\u8865\u4ec0\u4e48\u201d<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"ds-markdown-paragraph\">\u5e15\u91d1\u68ee\u75c5\u8fd0\u52a8\u75c7\u72b6\u7684\u6839\u6e90\uff0c\u662f\u5927\u8111\u9ed1\u8d28\u533a\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u7684\u9000\u5316\u548c\u6b7b\u4ea1\uff0c\u5bfc\u81f4\u795e\u7ecf\u9012\u8d28\u201c\u591a\u5df4\u80fa\u201d\u4e25\u91cd\u4e0d\u8db3\u3002\u56e0\u6b64\uff0c\u836f\u7269\u6cbb\u7597\u7684\u6838\u5fc3\u6218\u7565\u5c31\u662f\u901a\u8fc7\u5404\u79cd\u9014\u5f84\uff0c<strong>\u63d0\u5347\u5927\u8111\u5185\u591a\u5df4\u80fa\u7684\u6c34\u5e73\u6216\u529f\u80fd<\/strong>The<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%BA%8C%E3%80%81_%E6%B2%BB%E7%96%97%E5%B8%95%E9%87%91%E6%A3%AE%E7%97%85%E7%9A%84%E8%8D%AF%E7%89%A9%E6%9C%89%E5%93%AA%E5%87%A0%E7%A7%8D%EF%BC%9F6%E5%A4%A7%E6%A0%B8%E5%BF%83%E8%8D%AF%E7%89%A9%E7%B1%BB%E5%88%AB%E8%AF%A6%E8%A7%A3\"><\/span><strong>\u4e8c\u3001 \u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u836f\u7269\u6709\u54ea\u51e0\u79cd\uff1f6\u5927\u6838\u5fc3\u836f\u7269\u7c7b\u522b\u8be6\u89e3<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"%E6%B2%BB%E7%96%97%E5%B8%95%E9%87%91%E6%A3%AE%E7%97%85%E8%BF%90%E5%8A%A8%E7%97%87%E7%8A%B6%E7%9A%84%E8%8D%AF%E7%89%A9\"><\/span><span dir=\"auto\">\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u8fd0\u52a8\u75c7\u72b6\u7684\u836f\u7269<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<div class=\"table-responsive\">\n<table class=\"table\">\n<thead>\n<tr>\n<th><strong><span dir=\"auto\">\u7c7b\u522b<\/span><\/strong><\/th>\n<th><strong><span dir=\"auto\">\u901a\u7528\u7684<\/span><\/strong><\/th>\n<\/tr>\n<tr>\n<th><span dir=\"auto\">\u589e\u52a0\u5927\u8111\u591a\u5df4\u80fa\u6c34\u5e73\u7684\u836f\u7269<\/span><\/th>\n<th><span dir=\"auto\">\u5361\u6bd4\u591a\u5df4-\u5de6\u65cb\u591a\u5df4<\/span><\/th>\n<\/tr>\n<tr>\n<th><span dir=\"auto\">\u6a21\u62df\u591a\u5df4\u80fa\u7684\u836f\u7269\uff08\u591a\u5df4\u80fa\u6fc0\u52a8\u5242\uff09<\/span><\/th>\n<th><span dir=\"auto\">\u963f\u6251<\/span><br \/>\n<span dir=\"auto\">\u5417\u5561 \u666e\u62c9\u514b\u7d22<\/span><br \/>\n<span dir=\"auto\">\u7f57\u5339\u5c3c\u7f57<\/span><br \/>\n<span dir=\"auto\">\u7f57\u66ff\u6208\u6c40<\/span><\/th>\n<\/tr>\n<tr>\n<th><span dir=\"auto\">\u6291\u5236\u591a\u5df4\u80fa\u5206\u89e3\u7684\u836f\u7269\uff08MAO-B\u6291\u5236\u5242\uff09<\/span><\/th>\n<th><span dir=\"auto\">\u96f7\u6c99\u5409\u5170<\/span><br \/>\n<span dir=\"auto\">\u53f8\u6765\u5409\u5170\uff08deprenyl\uff09<\/span><\/th>\n<\/tr>\n<tr>\n<th><span dir=\"auto\">\u6291\u5236\u591a\u5df4\u80fa\u5206\u89e3\u7684\u836f\u7269\uff08COMT \u6291\u5236\u5242\uff09<\/span><\/th>\n<th><span dir=\"auto\">\u6069\u4ed6\u5361\u670b<\/span><br \/>\n<span dir=\"auto\">\u6258\u5361\u670b<\/span><\/th>\n<\/tr>\n<tr>\n<th><span dir=\"auto\">\u964d\u4f4e\u4e59\u9170\u80c6\u78b1\u4f5c\u7528\u7684\u836f\u7269\uff08\u6297\u80c6\u78b1\u836f\u7269\uff09<\/span><\/th>\n<th><span dir=\"auto\">\u82c4\u6258\u54c1 \u4e59\u6c27<\/span><br \/>\n<span dir=\"auto\">\u4e19\u55ea \u82ef<\/span><br \/>\n<span dir=\"auto\">\u6d77\u7d22<\/span><\/th>\n<\/tr>\n<tr>\n<th><span dir=\"auto\">\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u4f5c\u7528\u673a\u5236\u4e0d\u660e\u7684\u836f\u7269<\/span><\/th>\n<th><span dir=\"auto\">\u91d1\u521a\u70f7\u80fa<\/span><\/th>\n<\/tr>\n<\/thead>\n<\/table>\n<\/div>\n<h2 data-start=\"397\" data-end=\"421\"><span class=\"ez-toc-section\" id=\"01%E3%80%81%E5%B7%A6%E6%97%8B%E5%A4%9A%E5%B7%B4%EF%BC%9A%E4%BB%8D%E7%84%B6%E6%98%AF%E5%B8%95%E9%87%91%E6%A3%AE%E6%B2%BB%E7%96%97%E7%9A%84%E2%80%9C%E9%87%91%E6%A0%87%E5%87%86%E2%80%9D\"><\/span>01\u3001\u5de6\u65cb\u591a\u5df4\uff1a\u4ecd\u7136\u662f\u5e15\u91d1\u68ee\u6cbb\u7597\u7684\u201c\u91d1\u6807\u51c6\u201d<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-start=\"423\" data-end=\"591\"><strong data-start=\"423\" data-end=\"431\">\u4ee3\u8868\u836f\u7269<\/strong>\uff1a\u7f8e\u591a\u5df4\uff08Madopar\uff09\u3001\u606f\u5b81\uff08Sinemet\uff09\u7b49<\/p>\n<p data-start=\"423\" data-end=\"591\"><strong data-start=\"460\" data-end=\"468\">\u4f5c\u7528\u539f\u7406<\/strong>\uff1a\u5de6\u65cb\u591a\u5df4\uff08Levodopa\uff09\u662f\u591a\u5df4\u80fa\u7684\u524d\u4f53\uff0c\u53ef\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c\uff0c\u5728\u8111\u5185\u88ab\u8f6c\u5316\u4e3a\u591a\u5df4\u80fa\uff0c\u4ece\u800c\u8865\u5145\u7f3a\u5931\u7684\u795e\u7ecf\u9012\u8d28\u3002\u7531\u4e8e\u5de6\u65cb\u591a\u5df4\u5728\u5916\u5468\u5bb9\u6613\u88ab\u5206\u89e3\uff0c\u901a\u5e38\u9700\u4e0e**\u5916\u5468\u8131\u7fa7\u9176\u6291\u5236\u5242\uff08\u5982\u5361\u6bd4\u591a\u5df4\u3001\u82c4\u4e1d\u80bc\uff09**\u8054\u5408\u4f7f\u7528\uff0c\u4ee5\u51cf\u5c11\u5916\u5468\u4ee3\u8c22\u3001\u63d0\u9ad8\u8111\u5185\u5229\u7528\u7387\u3002<\/p>\n<p data-start=\"593\" data-end=\"637\"><strong data-start=\"593\" data-end=\"601\">\u9002\u7528\u4eba\u7fa4<\/strong>\uff1a\u9002\u5408\u75c7\u72b6\u8f83\u91cd\u3001\u5bf9\u751f\u6d3b\u5f71\u54cd\u660e\u663e\u7684\u60a3\u8005\uff0c\u662f\u76ee\u524d\u6700\u6709\u6548\u7684\u5bf9\u75c7\u836f\u7269\u3002<\/p>\n<p data-start=\"639\" data-end=\"651\"><strong data-start=\"639\" data-end=\"648\">\u5e38\u89c1\u526f\u4f5c\u7528<\/strong>\uff1a\u6076\u5fc3\u3001\u5455\u5410\u3001\u4f4e\u8840\u538b<\/p>\n<ul data-start=\"652\" data-end=\"774\">\n<li data-start=\"666\" data-end=\"774\">\n<p data-start=\"668\" data-end=\"687\">\u957f\u671f\u4f7f\u7528\u53ef\u5bfc\u81f4<strong data-start=\"675\" data-end=\"684\">\u8fd0\u52a8\u5e76\u53d1\u75c7<\/strong>::<\/p>\n<ul data-start=\"690\" data-end=\"774\">\n<li data-start=\"690\" data-end=\"737\">\n<p data-start=\"692\" data-end=\"737\">\u201c\u5242\u672b\u73b0\u8c61\u201d\uff08wearing-off\uff09\uff1a\u836f\u6548\u6301\u7eed\u65f6\u95f4\u7f29\u77ed\uff0c\u75c7\u72b6\u5728\u4e0b\u4e00\u6b21\u670d\u836f\u524d\u91cd\u65b0\u51fa\u73b0\u3002<\/p>\n<\/li>\n<li data-start=\"740\" data-end=\"774\">\n<p data-start=\"742\" data-end=\"774\">\u201c\u5f02\u52a8\u75c7\u201d\uff08dyskinesia\uff09\uff1a\u975e\u81ea\u4e3b\u6027\u821e\u8e48\u6837\u6216\u626d\u52a8\u6837\u52a8\u4f5c\u3002<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p data-start=\"776\" data-end=\"787\"><strong data-start=\"776\" data-end=\"784\">\u7ba1\u7406\u7b56\u7565<\/strong>\uff1a\u5c06\u6bcf\u65e5\u5242\u91cf\u5206\u6b21\u670d\u7528\u6216\u8c03\u6574\u7528\u836f\u95f4\u9694\uff1b\u8054\u5408\u5176\u4ed6\u7c7b\u836f\u7269\uff08\u5982MAO-B\u6291\u5236\u5242\u3001COMT\u6291\u5236\u5242\uff09\u5ef6\u957f\u836f\u6548\uff1b\u6216\u4f7f\u7528<strong data-start=\"851\" data-end=\"859\">\u63a7\u91ca\u5236\u5242<\/strong>,<strong data-start=\"860\" data-end=\"869\">\u80a0\u9053\u6cf5\u7597\u6cd5<\/strong>\u6539\u5584\u6ce2\u52a8\u3002<\/p>\n<p data-start=\"776\" data-end=\"787\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19866\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/ac97b3308a2756b8105a33293c7eeb82.png\" alt=\"\" width=\"660\" height=\"350\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/ac97b3308a2756b8105a33293c7eeb82.png 660w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/ac97b3308a2756b8105a33293c7eeb82-300x159.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/ac97b3308a2756b8105a33293c7eeb82-18x10.png 18w\" sizes=\"(max-width: 660px) 100vw, 660px\" \/><\/p>\n<h2 data-start=\"881\" data-end=\"903\"><span class=\"ez-toc-section\" id=\"02%E3%80%81%E5%A4%9A%E5%B7%B4%E8%83%BA%E5%8F%97%E4%BD%93%E6%BF%80%E5%8A%A8%E5%89%82%EF%BC%9A%E6%A8%A1%E4%BB%BF%E5%A4%9A%E5%B7%B4%E8%83%BA%E7%9A%84%E4%BD%9C%E7%94%A8\"><\/span>02\u3001\u591a\u5df4\u80fa\u53d7\u4f53\u6fc0\u52a8\u5242\uff1a\u6a21\u4eff\u591a\u5df4\u80fa\u7684\u4f5c\u7528<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-start=\"905\" data-end=\"974\"><strong data-start=\"905\" data-end=\"913\">\u4ee3\u8868\u836f\u7269<\/strong>\uff1a\u666e\u62c9\u514b\u7d22\uff08Pramipexole\uff09\u3001\u7f57\u5339\u5c3c\u7f57\uff08Ropinirole\uff09\u3001\u5421\u8d1d\u5730\u5c14\uff08Piribedil\uff09\u3001\u7f57\u66ff\u6208\u6c40\u8d34\u7247\u7b49<\/p>\n<p data-start=\"976\" data-end=\"1022\"><strong data-start=\"976\" data-end=\"984\">\u4f5c\u7528\u539f\u7406<\/strong>\uff1a\u76f4\u63a5\u523a\u6fc0\u8111\u5185\u7684\u591a\u5df4\u80fa\u53d7\u4f53\uff0c\u6a21\u62df\u591a\u5df4\u80fa\u7684\u4f5c\u7528\uff0c\u65e0\u9700\u5728\u8111\u5185\u4ee3\u8c22\u8f6c\u5316\u3002<\/p>\n<p data-start=\"1024\" data-end=\"1035\"><strong data-start=\"1024\" data-end=\"1032\">\u9002\u7528\u573a\u666f<\/strong>\uff1a\u65e9\u671f\u8f7b\u4e2d\u5ea6\u5e15\u91d1\u68ee\u75c5\u60a3\u8005\uff0c\u53ef\u5ef6\u7f13\u4f7f\u7528\u5de6\u65cb\u591a\u5df4\u7684\u65f6\u95f4\uff1b\u6216\u4e0e\u5de6\u65cb\u591a\u5df4\u8054\u5408\uff0c\u51cf\u5c11\u8fd0\u52a8\u6ce2\u52a8\u3002<\/p>\n<p data-start=\"1088\" data-end=\"1098\"><strong data-start=\"1088\" data-end=\"1095\">\u526f\u4f5c\u7528<\/strong>\uff1a\u55dc\u7761\u3001\u5e7b\u89c9\u3001\u51b2\u52a8\u63a7\u5236\u969c\u788d\uff08\u5982\u8d2d\u7269\u51b2\u52a8\u3001\u6027\u51b2\u52a8\u7b49\uff09\uff1b\u5916\u5468\u6c34\u80bf\u3001\u6076\u5fc3\u3002<\/p>\n<p data-start=\"1141\" data-end=\"1210\"><strong data-start=\"1141\" data-end=\"1147\">\u4f18\u70b9<\/strong>\uff1a\u5f15\u53d1\u201c\u5f02\u52a8\u75c7\u201d\u7684\u98ce\u9669\u8f83\u4f4e\uff0c\u836f\u6548\u76f8\u5bf9\u5e73\u7a33\u3002\u5c24\u5176\u662f<strong data-start=\"1177\" data-end=\"1187\">\u7f57\u66ff\u6208\u6c40\u8d34\u7247<\/strong>\uff0c\u80fd\u5b9e\u73b024\u5c0f\u65f6\u836f\u7269\u91ca\u653e\uff0c\u9002\u5408\u591c\u95f4\u75c7\u72b6\u660e\u663e\u8005\u3002<\/p>\n<p data-start=\"1141\" data-end=\"1210\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19865\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/66207d474d7d2017be94e90c0e72b122.jpeg\" alt=\"\" width=\"660\" height=\"397\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/66207d474d7d2017be94e90c0e72b122.jpeg 660w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/66207d474d7d2017be94e90c0e72b122-300x180.jpeg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/66207d474d7d2017be94e90c0e72b122-18x12.jpeg 18w\" sizes=\"(max-width: 660px) 100vw, 660px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-19864\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/9582976fc770846c078c1af9b51b7848.png\" alt=\"\" width=\"618\" height=\"397\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/9582976fc770846c078c1af9b51b7848.png 1080w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/9582976fc770846c078c1af9b51b7848-300x193.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/9582976fc770846c078c1af9b51b7848-1024x658.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/9582976fc770846c078c1af9b51b7848-768x494.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/9582976fc770846c078c1af9b51b7848-18x12.png 18w\" sizes=\"(max-width: 618px) 100vw, 618px\" \/><\/p>\n<hr data-start=\"1212\" data-end=\"1215\" \/>\n<h2 data-start=\"1217\" data-end=\"1244\"><span class=\"ez-toc-section\" id=\"03%E3%80%81MAO-B%E6%8A%91%E5%88%B6%E5%89%82%EF%BC%9A%E5%BB%B6%E9%95%BF%E5%A4%9A%E5%B7%B4%E8%83%BA%E5%AF%BF%E5%91%BD%E7%9A%84%E2%80%9C%E8%BE%85%E5%8A%A9%E5%85%B5%E2%80%9D\"><\/span>03\u3001MAO-B\u6291\u5236\u5242\uff1a\u5ef6\u957f\u591a\u5df4\u80fa\u5bff\u547d\u7684\u201c\u8f85\u52a9\u5175\u201d<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-start=\"1246\" data-end=\"1307\"><strong data-start=\"1246\" data-end=\"1254\">\u4ee3\u8868\u836f\u7269<\/strong>\uff1a\u53f8\u6765\u5409\u5170\uff08Selegiline\uff09\u3001\u96f7\u6c99\u5409\u5170\uff08Rasagiline\uff09\u3001\u6c99\u82ac\u9170\u80fa\uff08Safinamide\uff09<\/p>\n<p data-start=\"1309\" data-end=\"1357\"><strong data-start=\"1309\" data-end=\"1317\">\u4f5c\u7528\u539f\u7406<\/strong>\uff1a\u6291\u5236\u8111\u5185\u5355\u80fa\u6c27\u5316\u9176B\uff08MAO-B\uff09\uff0c\u51cf\u5c11\u591a\u5df4\u80fa\u5206\u89e3\uff0c\u5ef6\u957f\u5176\u4f5c\u7528\u65f6\u95f4\u3002<\/p>\n<p data-start=\"1359\" data-end=\"1370\"><strong data-start=\"1359\" data-end=\"1367\">\u9002\u7528\u573a\u666f<\/strong>::<\/p>\n<ul data-start=\"1371\" data-end=\"1413\">\n<li data-start=\"1371\" data-end=\"1390\">\n<p data-start=\"1373\" data-end=\"1390\">\u65e9\u671f\u5355\u836f\u4f7f\u7528\uff0c\u53ef\u5ef6\u7f13\u75c7\u72b6\u8fdb\u5c55\uff1b<\/p>\n<\/li>\n<li data-start=\"1391\" data-end=\"1413\">\n<p data-start=\"1393\" data-end=\"1413\">\u4e0e\u5de6\u65cb\u591a\u5df4\u5408\u7528\uff0c\u53ef\u6539\u5584\u201c\u5242\u672b\u73b0\u8c61\u201d\u3002<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1415\" data-end=\"1463\"><strong data-start=\"1415\" data-end=\"1422\">\u526f\u4f5c\u7528<\/strong>\uff1a\u8f7b\u5ea6\u5931\u7720\u3001\u5934\u75db\u3001\u8840\u538b\u6ce2\u52a8\u3002\u603b\u4f53\u8010\u53d7\u6027\u826f\u597d\uff0c\u9002\u5408\u8001\u5e74\u60a3\u8005\u957f\u671f\u4f7f\u7528\u3002<\/p>\n<p data-start=\"1465\" data-end=\"1503\"><strong data-start=\"1465\" data-end=\"1478\">\u65b0\u4e00\u4ee3\u836f\u7269\u6c99\u82ac\u9170\u80fa<\/strong>\u8fd8\u5177\u6709<strong data-start=\"1481\" data-end=\"1492\">\u8c37\u6c28\u9178\u8c03\u8282\u4f5c\u7528<\/strong>\uff0c\u80fd\u66f4\u597d\u6539\u5584\u8fd0\u52a8\u6ce2\u52a8\u3002<\/p>\n<p data-start=\"1465\" data-end=\"1503\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19863\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/91934a67a57cae2ac8e2544562607f05.png\" alt=\"\" width=\"510\" height=\"266\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/91934a67a57cae2ac8e2544562607f05.png 510w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/91934a67a57cae2ac8e2544562607f05-300x156.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/91934a67a57cae2ac8e2544562607f05-18x9.png 18w\" sizes=\"(max-width: 510px) 100vw, 510px\" \/><\/p>\n<hr data-start=\"1505\" data-end=\"1508\" \/>\n<h2 data-start=\"1510\" data-end=\"1535\"><span class=\"ez-toc-section\" id=\"04%E3%80%81%E5%84%BF%E8%8C%B6%E9%85%9A-O-%E7%94%B2%E5%9F%BA%E8%BD%AC%E7%A7%BB%E9%85%B6%E6%8A%91%E5%88%B6%E5%89%82%EF%BC%88COMT%EF%BC%89%EF%BC%9A%E5%BB%B6%E9%95%BF%E5%B7%A6%E6%97%8B%E5%A4%9A%E5%B7%B4%E5%9C%A8%E4%BD%93%E5%86%85%E7%9A%84%E5%AF%BF%E5%91%BD\"><\/span>04\u3001<strong>\u513f\u8336\u915a-O-\u7532\u57fa\u8f6c\u79fb\u9176\u6291\u5236\u5242\uff08COMT\uff09<\/strong>\uff1a\u5ef6\u957f\u5de6\u65cb\u591a\u5df4\u5728\u4f53\u5185\u7684\u5bff\u547d<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-start=\"1537\" data-end=\"1580\"><strong data-start=\"1537\" data-end=\"1545\">\u4ee3\u8868\u836f\u7269<\/strong>\uff1a\u6069\u4ed6\u5361\u670b\uff08Entacapone\uff09\u3001\u5965\u6bd4\u5361\u670b\uff08Opicapone\uff09<\/p>\n<p data-start=\"1582\" data-end=\"1640\"><strong data-start=\"1582\" data-end=\"1590\">\u4f5c\u7528\u539f\u7406<\/strong>\uff1a\u6291\u5236\u513f\u8336\u915a-O-\u7532\u57fa\u8f6c\u79fb\u9176\uff08COMT\uff09\uff0c\u51cf\u5c11\u5de6\u65cb\u591a\u5df4\u5728\u5916\u5468\u7684\u4ee3\u8c22\uff0c\u4f7f\u5176\u5728\u8840\u6db2\u4e2d\u7ef4\u6301\u66f4\u4e45\u3002<\/p>\n<p data-start=\"1642\" data-end=\"1683\"><strong data-start=\"1642\" data-end=\"1650\">\u9002\u7528\u573a\u666f<\/strong>\uff1a\u6069\u4ed6\u5361\u670b\u76ee\u524d\u5728\u5e15\u91d1\u68ee\u75c5\u4e2d\u4e3b\u8981\u4f5c\u4e3a\u4e2d\u665a\u671f\u6dfb\u52a0\u6cbb\u7597\uff0c\u80fd\u8fdb\u4e00\u6b65\u6539\u5584\u5e15\u91d1\u68ee\u75c5\u7684\u8fd0\u52a8\u75c7\u72b6\uff0c\u5bf9\u75c7\u72b6\u6ce2\u52a8\u4e5f\u6709\u4e00\u5b9a\u6539\u5584\u4f5c\u7528\u3002\u9700\u8981\u6ce8\u610f\u7684\u662f\uff0c<strong>\u6069\u4ed6\u5361\u670b\u987b\u4e0e\u590d\u65b9\u5de6\u65cb\u591a\u5df4\u4e00\u8d77\u670d\u7528\uff0c\u5355\u7528\u65e0\u6548<\/strong>The<\/p>\n<p data-start=\"1685\" data-end=\"1713\"><strong data-start=\"1685\" data-end=\"1692\">\u526f\u4f5c\u7528<\/strong>\uff1a\u8179\u6cfb\u3001\u5c3f\u6db2\u5448\u6a59\u8272\u3001\u52a0\u91cd\u5f02\u52a8\u75c7\u3002<\/p>\n<p data-start=\"1715\" data-end=\"1757\"><strong data-start=\"1715\" data-end=\"1721\">\u63d0\u793a<\/strong>\uff1aCOMT\u6291\u5236\u5242\u672c\u8eab\u65e0\u6297\u5e15\u91d1\u68ee\u4f5c\u7528\uff0c\u4ec5\u7528\u4e8e\u201c\u5f3a\u5316\u5de6\u65cb\u591a\u5df4\u201d\u7684\u6548\u679c\u3002<\/p>\n<p data-start=\"1715\" data-end=\"1757\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19862\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/469feb833195445c2c5560575370aac0.png\" alt=\"\" width=\"529\" height=\"292\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/469feb833195445c2c5560575370aac0.png 529w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/469feb833195445c2c5560575370aac0-300x166.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/469feb833195445c2c5560575370aac0-18x10.png 18w\" sizes=\"(max-width: 529px) 100vw, 529px\" \/><\/p>\n<hr data-start=\"1759\" data-end=\"1762\" \/>\n<h2 data-start=\"1764\" data-end=\"1787\"><span class=\"ez-toc-section\" id=\"05%E3%80%81%E6%8A%97%E8%83%86%E7%A2%B1%E8%83%BD%E8%8D%AF%E7%89%A9%EF%BC%9A%E7%94%A8%E4%BA%8E%E9%9C%87%E9%A2%A4%E4%B8%BA%E4%B8%BB%E7%9A%84%E5%B9%B4%E8%BD%BB%E6%82%A3%E8%80%85\"><\/span>05\u3001\u6297\u80c6\u78b1\u80fd\u836f\u7269\uff1a\u7528\u4e8e\u9707\u98a4\u4e3a\u4e3b\u7684\u5e74\u8f7b\u60a3\u8005<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-start=\"1789\" data-end=\"1833\"><strong data-start=\"1789\" data-end=\"1797\">\u4ee3\u8868\u836f\u7269<\/strong>\uff1a\u82ef\u6d77\u7d22\uff08Artane\uff09\u3001\u4e09\u5df1\u82ac\u5730\uff08Trihexyphenidyl\uff09<\/p>\n<p data-start=\"1835\" data-end=\"1885\"><strong data-start=\"1835\" data-end=\"1843\">\u4f5c\u7528\u539f\u7406<\/strong>\uff1a\u5e15\u91d1\u68ee\u75c5\u60a3\u8005\u591a\u5df4\u80fa\u51cf\u5c11\u3001\u4e59\u9170\u80c6\u78b1\u76f8\u5bf9\u8fc7\u591a\uff0c\u6297\u80c6\u78b1\u836f\u901a\u8fc7\u6062\u590d\u5e73\u8861\u51cf\u8f7b\u9707\u98a4\u3002<\/p>\n<p data-start=\"1887\" data-end=\"1914\"><strong data-start=\"1887\" data-end=\"1895\">\u9002\u7528\u4eba\u7fa4<\/strong>\uff1a\u9707\u98a4\u4e3a\u4e3b\u3001\u5e74\u9f84\u8f83\u8f7b\u7684\u60a3\u8005\u3002<\/p>\n<p data-start=\"1916\" data-end=\"1953\"><strong data-start=\"1916\" data-end=\"1923\">\u526f\u4f5c\u7528<\/strong>\uff1a\u8bb0\u5fc6\u529b\u4e0b\u964d\u3001\u53e3\u5e72\u3001\u4fbf\u79d8\u3001\u5c3f\u6f74\u7559\u7b49\uff0c\u8001\u5e74\u60a3\u8005\u614e\u7528\u3002<\/p>\n<p data-start=\"1916\" data-end=\"1953\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-19861 aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/46cb9998a0debc82076afdf409da11d4.jpeg\" alt=\"\" width=\"237\" height=\"370\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/46cb9998a0debc82076afdf409da11d4.jpeg 661w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/46cb9998a0debc82076afdf409da11d4-192x300.jpeg 192w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/46cb9998a0debc82076afdf409da11d4-657x1024.jpeg 657w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/46cb9998a0debc82076afdf409da11d4-8x12.jpeg 8w\" sizes=\"(max-width: 237px) 100vw, 237px\" \/><\/p>\n<hr data-start=\"1955\" data-end=\"1958\" \/>\n<h2 data-start=\"1960\" data-end=\"1993\"><span class=\"ez-toc-section\" id=\"06%E3%80%81%E9%87%91%E5%88%9A%E7%83%B7%E8%83%BA%EF%BC%88Amantadine%EF%BC%89%EF%BC%9A%E5%85%BC%E5%85%B7%E6%8A%97%E7%97%85%E6%AF%92%E4%B8%8E%E6%8A%97%E5%BC%82%E5%8A%A8%E4%BD%9C%E7%94%A8\"><\/span>06\u3001\u91d1\u521a\u70f7\u80fa\uff08Amantadine\uff09\uff1a\u517c\u5177\u6297\u75c5\u6bd2\u4e0e\u6297\u5f02\u52a8\u4f5c\u7528<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-start=\"1995\" data-end=\"2049\"><strong data-start=\"1995\" data-end=\"2003\">\u4f5c\u7528\u539f\u7406<\/strong>\uff1a\u4fc3\u8fdb\u591a\u5df4\u80fa\u91ca\u653e\u5e76\u6291\u5236\u518d\u6444\u53d6\uff0c\u540c\u65f6\u5177\u6709NMDA\u53d7\u4f53\u62ee\u6297\u4f5c\u7528\uff0c\u53ef\u7f13\u89e3<strong data-start=\"2039\" data-end=\"2046\">\u5f02\u52a8\u75c7<\/strong>The<\/p>\n<p data-start=\"2051\" data-end=\"2062\"><strong data-start=\"2051\" data-end=\"2059\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u9002\u7528\u573a\u666f<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">::<\/span><\/span><\/p>\n<ul data-start=\"2063\" data-end=\"2100\">\n<li data-start=\"2063\" data-end=\"2077\">\n<p data-start=\"2065\" data-end=\"2077\">\u8f7b\u5ea6\u75c7\u72b6\u671f\u5355\u836f\u4f7f\u7528\uff1b<\/p>\n<\/li>\n<li data-start=\"2078\" data-end=\"2100\">\n<p data-start=\"2080\" data-end=\"2100\">\u6216\u7528\u4e8e\u63a7\u5236\u5de6\u65cb\u591a\u5df4\u8bf1\u53d1\u7684\u8fd0\u52a8\u5e76\u53d1\u75c7\u3002<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"2102\" data-end=\"2131\"><strong data-start=\"2102\" data-end=\"2109\">\u526f\u4f5c\u7528<\/strong>\uff1a\u5931\u7720\u3001\u6c34\u80bf\u3001\u5e7b\u89c9\u3001\u76ae\u80a4\u7f51\u72b6\u9752\u6591\u3002<\/p>\n<p data-start=\"2102\" data-end=\"2131\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-19860\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/e1acd5bb652f9b3fbe46b17a2c5a2040.png\" alt=\"\" width=\"790\" height=\"477\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/e1acd5bb652f9b3fbe46b17a2c5a2040.png 1000w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/e1acd5bb652f9b3fbe46b17a2c5a2040-300x181.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/e1acd5bb652f9b3fbe46b17a2c5a2040-768x464.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/e1acd5bb652f9b3fbe46b17a2c5a2040-18x12.png 18w\" sizes=\"(max-width: 790px) 100vw, 790px\" \/><\/p>\n<p data-start=\"2102\" data-end=\"2131\"><!--more--><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%B8%89%E3%80%81_%E9%95%BF%E6%9C%9F%E6%B2%BB%E7%96%97%E7%9A%84%E6%A0%B8%E5%BF%83%E6%8C%91%E6%88%98%EF%BC%9A%E8%BF%90%E5%8A%A8%E5%B9%B6%E5%8F%91%E7%97%87%E7%9A%84%E7%AE%A1%E7%90%86\"><\/span><strong>\u4e09\u3001 \u957f\u671f\u6cbb\u7597\u7684\u6838\u5fc3\u6311\u6218\uff1a\u8fd0\u52a8\u5e76\u53d1\u75c7\u7684\u7ba1\u7406<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"ds-markdown-paragraph\">\u968f\u7740\u75c5\u7a0b\u5ef6\u957f\uff0c\u5de6\u65cb\u591a\u5df4\u7684\u7597\u6548\u4f1a\u51fa\u73b0\u6ce2\u52a8\uff0c\u4e3b\u8981\u4f53\u73b0\u4e3a\u4e24\u79cd\u8fd0\u52a8\u5e76\u53d1\u75c7\uff1a<\/p>\n<h3 class=\"ds-markdown-paragraph\"><span class=\"ez-toc-section\" id=\"1_%E5%89%82%E6%9C%AB%E7%8E%B0%E8%B1%A1%E2%80%94%E2%80%94%E8%8D%AF%E6%95%88%E2%80%9C%E6%96%AD%E7%94%B5%E2%80%9D\"><\/span><strong>1. \u5242\u672b\u73b0\u8c61\u2014\u2014\u836f\u6548\u201c\u65ad\u7535\u201d<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u662f\u4ec0\u4e48\uff1a<\/strong>\u00a0\u6307\u6bcf\u6b21\u670d\u836f\u540e\uff0c\u836f\u6548\u7ef4\u6301\u65f6\u95f4\u8d8a\u6765\u8d8a\u77ed\uff0c\u5728\u4e0b\u4e00\u6b21\u670d\u836f\u524d\uff0c\u75c7\u72b6\uff08\u5982\u50f5\u786c\u3001\u884c\u52a8\u56f0\u96be\uff09\u518d\u6b21\u51fa\u73b0\uff0c\u5982\u540c\u201c\u65ad\u7535\u201d\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u5982\u4f55\u7ba1\u7406\uff1a<\/strong><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u8c03\u6574\u670d\u836f\u65b9\u6848\uff1a<\/strong>\u00a0\u589e\u52a0\u670d\u836f\u6b21\u6570\u3001\u6362\u7528\u7f13\u91ca\u5242\u578b\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u6dfb\u52a0\u8f85\u52a9\u836f\u7269\uff1a<\/strong>\u00a0\u52a0\u7528COMT\u6291\u5236\u5242\u6216MAO-B\u6291\u5236\u5242\u6765\u5ef6\u957f\u5de6\u65cb\u591a\u5df4\u7684\u6548\u679c\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u8c03\u6574\u996e\u98df\uff1a<\/strong>\u00a0\u9ad8\u86cb\u767d\u98df\u7269\u53ef\u80fd\u5f71\u54cd\u5de6\u65cb\u591a\u5df4\u5438\u6536\uff0c\u53ef\u5c1d\u8bd5\u5728\u9910\u524d1\u5c0f\u65f6\u6216\u9910\u540e1.5\u5c0f\u65f6\u670d\u836f\u3002<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 class=\"ds-markdown-paragraph\"><span class=\"ez-toc-section\" id=\"2_%E5%BC%82%E5%8A%A8%E7%97%87%E2%80%94%E2%80%94%E8%8D%AF%E6%95%88%E2%80%9C%E8%BF%87%E9%87%8F%E2%80%9D\"><\/span><strong>2. \u5f02\u52a8\u75c7\u2014\u2014\u836f\u6548\u201c\u8fc7\u91cf\u201d<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u662f\u4ec0\u4e48\uff1a<\/strong>\u00a0\u6307\u5728\u836f\u6548\u9ad8\u5cf0\u671f\uff0c\u51fa\u73b0\u5934\u3001\u9888\u3001\u56db\u80a2\u4e0d\u81ea\u4e3b\u7684\u3001\u821e\u8e48\u6837\u7684\u626d\u52a8\u52a8\u4f5c\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u5982\u4f55\u7ba1\u7406\uff1a<\/strong><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u8c03\u6574\u5de6\u65cb\u591a\u5df4\uff1a<\/strong>\u00a0\u51cf\u5c11\u5355\u6b21\u5242\u91cf\uff0c\u589e\u52a0\u670d\u836f\u9891\u7387\uff08\u201c\u7ec6\u6c34\u957f\u6d41\u201d\u7b56\u7565\uff09\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u6362\u7528\u7f13\u91ca\u5242\u578b\uff1a<\/strong>\u00a0\u4f7f\u8840\u6db2\u6d53\u5ea6\u66f4\u5e73\u7a33\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u6dfb\u52a0\u836f\u7269\uff1a<\/strong>\u00a0\u4f7f\u7528\u91d1\u521a\u70f7\u80fa\u6216\u6c2f\u6c2e\u5e73\uff08\u9700\u4e25\u5bc6\u76d1\u6d4b\u767d\u7ec6\u80de\uff09\u6765\u6291\u5236\u5f02\u52a8\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u624b\u672f\u6cbb\u7597\uff1a<\/strong>\u00a0\u5bf9\u4e8e\u836f\u7269\u96be\u4ee5\u63a7\u5236\u7684\u4e25\u91cd\u5f02\u52a8\uff0c<strong>\u8111\u6df1\u90e8\u7535\u523a\u6fc0\u672f\uff08DBS\uff09<\/strong>\u00a0\u901a\u5e38\u662f\u6709\u6548\u7684\u9009\u62e9\u3002<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 data-start=\"2304\" data-end=\"2320\"><span class=\"ez-toc-section\" 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