{"id":19875,"date":"2025-10-22T15:10:26","date_gmt":"2025-10-22T07:10:26","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=19875"},"modified":"2025-10-22T14:58:59","modified_gmt":"2025-10-22T06:58:59","slug":"https-www-hjtdsm-cn-stem-cells-psc-19875-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/psc\/19875.html","title":{"rendered":"\u4ec0\u4e48\u662f\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\uff0c\u8c01\u5728\u8d44\u52a9iPSC\uff0c\u6b63\u5728\u8fdb\u884c\u54ea\u4e9b\u8bd5\u9a8c\uff1f"},"content":{"rendered":"<blockquote><p>\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPS\u7ec6\u80de\uff09\u53ef\u4ee5\u901a\u8fc7\u5c06\u6210\u719f\u7684\u6210\u4f53\u7ec6\u80de\u91cd\u65b0\u7f16\u7a0b\u56de\u80da\u80ce\u72b6\u6001\u800c\u5236\u6210\u3002iPS\u7ec6\u80de\u6e90\u81ea\u76ae\u80a4\u6216\u8840\u6db2\u7ec6\u80de\uff0c\u56e0\u6b64\u5e76\u65e0\u4e89\u8bae\uff0c\u56e0\u4e3a\u5b83\u4eec\u662f\u7531\u6210\u4f53\u7ec6\u80de\u5236\u6210\u7684\u3002\u4f5c\u4e3a<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/psc\/19798.html\/\" target=\"_blank\" rel=\"noopener\">pluripotent stem cell<\/a>\uff0c\u5b83\u4eec\u53ef\u4ee5\u5206\u5316\u5f62\u6210\u6784\u6210\u4eba\u4f53\u7684\u6240\u6709\u7ec4\u7ec7\u3002<\/p><\/blockquote>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" 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href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/psc\/19875.html\/#%E4%BB%80%E4%B9%88%E6%98%AF%E8%AF%B1%E5%AF%BC%E5%A4%9A%E8%83%BD%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88iPSC%EF%BC%89%EF%BC%8C%E8%B0%81%E5%9C%A8%E8%B5%84%E5%8A%A9iPSC%EF%BC%8C%E6%AD%A3%E5%9C%A8%E8%BF%9B%E8%A1%8C%E5%93%AA%E4%BA%9B%E8%AF%95%E9%AA%8C%EF%BC%9F\" >\u4ec0\u4e48\u662f\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\uff0c\u8c01\u5728\u8d44\u52a9iPSC\uff0c\u6b63\u5728\u8fdb\u884c\u54ea\u4e9b\u8bd5\u9a8c\uff1f<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/psc\/19875.html\/#1%E4%BB%80%E4%B9%88%E6%98%AF%E8%AF%B1%E5%AF%BC%E5%A4%9A%E8%83%BD%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9FiPS%E7%BB%86%E8%83%9E%E7%9A%84%E8%B5%B7%E6%BA%90%E4%B8%8E%E5%8F%91%E7%8E%B0\" >1.\u4ec0\u4e48\u662f\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff1fiPS\u7ec6\u80de\u7684\u8d77\u6e90\u4e0e\u53d1\u73b0<\/a><\/li><li 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href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/psc\/19875.html\/#%E5%9B%BD%E5%A4%96%E6%B6%89%E5%8F%8AiPSC%E8%A1%8D%E7%94%9F%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\" >\u56fd\u5916\u6d89\u53caiPSC\u884d\u751f\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/psc\/19875.html\/#%E5%9B%BD%E5%86%85%E6%B6%89%E5%8F%8A%E8%AF%B1%E5%AF%BC%E5%A4%9A%E8%83%BD%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\" >\u56fd\u5185\u6d89\u53ca\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/psc\/19875.html\/#%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%E4%BA%AE%E7%82%B9\" 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class=\"wp-block-list\">\n<li>iPS\u7ec6\u80de\u7684\u53d1\u73b0<\/li>\n<li>iPS\u7ec6\u80de\u4e0e\u80da\u80ce\u5e72\u7ec6\u80de<\/li>\n<li>\u53ef\u7528iPS\u7ec6\u80de\u6cbb\u7597\u7684\u75be\u75c5<\/li>\n<li>\u6d89\u53caiPSC\u884d\u751f\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/li>\n<li>iPS\u7ec6\u80de\u6280\u672f\u8d44\u91d1<\/li>\n<li>iPS\u7ec6\u80de\u5546\u4e1a\u5316<\/li>\n<li>\u5982\u4f55\u770b\u5f85iPS\u7ec6\u80de\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/li>\n<\/ol>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-55046\" title=\"\u4ec0\u4e48\u662f\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\uff0c\u8c01\u5728\u8d44\u52a9iPSC\uff0c\u6b63\u5728\u8fdb\u884c\u54ea\u4e9b\u8bd5\u9a8c\uff1f\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2025\/08\/2025082706481130.jpg\" sizes=\"(max-width: 1920px) 100vw, 1920px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2025\/08\/2025082706481130.jpg 1920w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2025\/08\/2025082706481130-768x441.jpg 768w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2025\/08\/2025082706481130-1536x882.jpg 1536w\" alt=\"\u4ec0\u4e48\u662f\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\uff0c\u8c01\u5728\u8d44\u52a9iPSC\uff0c\u6b63\u5728\u8fdb\u884c\u54ea\u4e9b\u8bd5\u9a8c\uff1f\" width=\"801\" height=\"460\" \/><figcaption><\/figcaption><\/figure>\n<p>\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de (iPS) \u662f\u4e00\u79cd\u6781\u5177\u6f5c\u529b\u7684\u7ec6\u80de\u7c7b\u578b\u3002\u8ba9\u6211\u4eec\u6df1\u5165\u4e86\u89e3iPS\u7ec6\u80de\u53ca\u5176\u591a\u79cd\u5e94\u7528\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"1%E4%BB%80%E4%B9%88%E6%98%AF%E8%AF%B1%E5%AF%BC%E5%A4%9A%E8%83%BD%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9FiPS%E7%BB%86%E8%83%9E%E7%9A%84%E8%B5%B7%E6%BA%90%E4%B8%8E%E5%8F%91%E7%8E%B0\"><\/span><strong>1.\u4ec0\u4e48\u662f\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff1f<\/strong><strong>iPS\u7ec6\u80de\u7684\u8d77\u6e90\u4e0e\u53d1\u73b0<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>2006\u5e74\uff0c\u65e5\u672c\u79d1\u5b66\u5bb6\u5c71\u4e2d\u4f38\u5f25\uff08Shinya 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class=\"ez-toc-section\" id=\"2%E8%AF%B1%E5%AF%BC%E5%A4%9A%E8%83%BD%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88iPS%EF%BC%89%E4%B8%8E%E8%83%9A%E8%83%8E%E5%B9%B2%E7%BB%86%E8%83%9E\"><\/span><strong>2.\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPS\uff09\u4e0e\u80da\u80ce\u5e72\u7ec6\u80de<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-start=\"448\" data-end=\"597\">\u80da\u80ce\u5e72\u7ec6\u80de\uff08Embryonic Stem Cells\uff0cESC\uff09\u662f\u6700\u65e9\u88ab\u53d1\u73b0\u7684\u591a\u80fd\u5e72\u7ec6\u80de\u3002\u79d1\u5b66\u5bb6\u4e8e1981\u5e74\u9996\u6b21\u4ece\u5c0f\u9f20\u80da\u80ce\u4e2d\u6210\u529f\u5206\u79bb\u51fa\u80da\u80ce\u5e72\u7ec6\u80de\uff0c\u76f4\u52301998\u5e74\uff0c\u4eba\u7c7b\u80da\u80ce\u5e72\u7ec6\u80de\u624d\u88ab\u6210\u529f\u63d0\u53d6\u3002ESC\u901a\u5e38\u53d6\u81ea\u53d7\u7cbe\u540e4\u20135\u5929\u7684\u56ca\u80da\u5185\u7ec6\u80de\u56e2\uff0c\u8fd9\u4e5f\u662f\u5176\u4f26\u7406\u4e89\u8bae\u7684\u6838\u5fc3\u6765\u6e90\u2014\u2014\u6bd5\u7adf\u80da\u80ce\u7684\u4f7f\u7528\u6d89\u53ca\u751f\u547d\u4f26\u7406\u95ee\u9898\u3002<\/p>\n<p data-start=\"599\" data-end=\"715\">\u76f8\u6bd4\u4e4b\u4e0b\uff0ciPS\u7ec6\u80de\u7684\u51fa\u73b0\u4e3a\u5e72\u7ec6\u80de\u7814\u7a76\u6253\u5f00\u4e86\u65b0\u7684\u5c40\u9762\u30022006\u5e74\uff0c\u7814\u7a76\u4eba\u5458\u5728\u5c0f\u9f20\u4e2d\u9996\u6b21\u6210\u529f\u8bf1\u5bfc\u51faiPS\u7ec6\u80de\uff0c\u7fcc\u5e74\u4fbf\u5728\u4eba\u7c7b\u7ec6\u80de\u4e2d\u5b9e\u73b0\u540c\u6837\u7a81\u7834\u3002\u7531\u4e8e\u4e0d\u4f9d\u8d56\u80da\u80ce\u6765\u6e90\uff0ciPS\u7ec6\u80de\u89c4\u907f\u4e86\u4f26\u7406\u95ee\u9898\uff0c\u4f7f\u5f97\u4eba\u7c7b\u7ec6\u80de\u5b9e\u9a8c\u5f97\u4ee5\u66f4\u52a0\u5e7f\u6cdb\u3001\u5b89\u5168\u5730\u5f00\u5c55\u3002<\/p>\n<p data-start=\"717\" data-end=\"818\">\u65e0\u8bba\u662fiPS\u7ec6\u80de\u8fd8\u662f\u80da\u80ce\u5e72\u7ec6\u80de\uff0c\u4e8c\u8005\u90fd\u5177\u5907\u201c\u591a\u80fd\u6027\u201d\u2014\u2014\u80fd\u591f\u5206\u5316\u6210\u7ea6200\u79cd\u4e0d\u540c\u7684\u4eba\u4f53\u7ec6\u80de\u7c7b\u578b\uff0c\u5305\u62ec\u795e\u7ecf\u7ec6\u80de\u3001\u5fc3\u808c\u7ec6\u80de\u3001\u809d\u7ec6\u80de\u7b49\u3002\u8fd9\u79cd\u80fd\u529b\u8ba9\u5b83\u4eec\u6210\u4e3a\u518d\u751f\u533b\u5b66\u3001\u75be\u75c5\u6a21\u578b\u6784\u5efa\u548c\u836f\u7269\u7b5b\u9009\u7b49\u9886\u57df\u7684\u6838\u5fc3\u8d44\u6e90\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"3%E5%8F%AF%E7%94%A8iPS%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%9A%84%E7%96%BE%E7%97%85\"><\/span><strong>3.\u53ef\u7528iPS\u7ec6\u80de\u6cbb\u7597\u7684\u75be\u75c5<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5c3d\u7ba1\u5168\u7403\u5c1a\u672a\u6279\u51c6\u4f7f\u7528iPS\u7ec6\u80de\u7597\u6cd5\uff0c\u4f46iPS\u7ec6\u80de\u5177\u6709\u6cbb\u7597\u591a\u79cd\u75be\u75c5\u7684\u6f5c\u529b\uff0c\u5305\u62ec\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li>diabetes<\/li>\n<li>\u5fc3\u810f\u75c5<\/li>\n<li>autoimmune disease<\/li>\n<li>\u5173\u8282\u708e<\/li>\n<li>\u5e15\u91d1\u68ee\u75c5\u548c\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7b49\u795e\u7ecf\u5e76\u53d1\u75c7<\/li>\n<li>\u9aa8\u79d1\u5e94\u7528<\/li>\n<li>\u4ee5\u53ca\u66f4\u591a<\/li>\n<\/ul>\n<p>\u76ee\u524d\uff0cCynata Therapeutics\uff08\u53ca\u5176\u5408\u4f5c\u4f19\u4f34 FUJIFILM\uff09\u3001Healios KK\uff08\u4e0e\u4f4f\u53cb\u5927\u65e5\u672c\u5236\u836f\u5408\u4f5c\uff09\u3001Century Therapeutics\uff08\u6536\u8d2d\u4e86 Clade Therapeutics\uff09\u3001\u5c0f\u91ce\u5236\u836f\u682a\u5f0f\u4f1a\u793e\u548c Fate Therapeutics \u662f\u552f\u4e00\u5728\u4eba\u7c7b\u60a3\u8005\u8eab\u4e0a\u8fdb\u884ciPSC\u884d\u751f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u5546\u4e1a\u516c\u53f8\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E5%9B%BD%E5%A4%96%E6%B6%89%E5%8F%8AiPSC%E8%A1%8D%E7%94%9F%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\"><\/span><strong>\u56fd\u5916\u6d89\u53caiPSC\u884d\u751f\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Cynata Therapeutics\u662f\u4e00\u5bb6\u6fb3\u5927\u5229\u4e9a\u516c\u53f8\uff0c\u5df2\u5b8c\u6210\u4e00\u9879I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u91cd\u70b9\u7814\u7a76CYP-001\uff08\u4e00\u79cd\u6e90\u81eaiPSC\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\uff09\u5728\u6cbb\u7597\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\uff08GVHD\uff09\u4e2d\u7684\u5e94\u7528\u3002\u8be5\u8bd5\u9a8c\u4e8e2018\u5e74\u8fdb\u884c\uff0c\u572816\u4f8b\u5bf9\u7c7b\u56fa\u9187\u8010\u836f\u7684GVHD\u60a3\u8005\u4e2d\u53d6\u5f97\u4e86\u6210\u529f\u3002<a href=\"https:\/\/announcements.asx.com.au\/asxpdf\/20200618\/pdf\/44jr653pvmxxx3.pdf\" target=\"_blank\" rel=\"nofollow noopener\">Cynata\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u4e00\u9879III\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u6d4b\u8bd5\u5176\u6e90\u81eaiPSC\u7684\u7ec6\u80de\u7597\u6cd5CYP 004<\/a>\uff0c\u8be5\u8bd5\u9a8c\u62db\u52df\u4e86440\u540d\u60a3\u8005\u3002<sup>[1]<\/sup><\/p>\n<p>Fate Therapeutics\u6b63\u5728\u8fdb\u884c\u4e00\u9879I\u671f\u8bd5\u9a8c (NCT03841110)\uff0c\u4ee5\u8bc4\u4f30\u5176\u5019\u9009\u4ea7\u54c1FT500\u4f5c\u4e3a\u5355\u4e00\u7597\u6cd5\u4ee5\u53ca\u4e0e\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u8054\u5408\u6cbb\u7597\u665a\u671f\u5b9e\u4f53\u7624\u60a3\u8005\u7684\u7597\u6548\u3002<\/p>\n<p>\u6b63\u5728\u8fdb\u884c\u6d89\u53caiPSC\u884d\u751f\u7ec6\u80de\u7597\u6cd5\u7684\u4eba\u4f53\u4ecb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u7684\u975e\u5546\u4e1a\u5b9e\u4f53\u5305\u62ec\uff1a<\/p>\n<p><strong>\u54e5\u5ef7\u6839\u5927\u5b66\u533b\u5b66\u4e2d\u5fc3\uff1a<\/strong>\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\u884d\u751f\u7684\u5de5\u7a0b\u5316\u4eba\u7c7b\u5fc3\u808c\u4f5c\u4e3a\u7ec8\u672b\u671f\u5fc3\u529b\u8870\u7aed\u751f\u7269\u5fc3\u5ba4\u8f85\u52a9\u7ec4\u7ec7\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027<a href=\"https:\/\/clinicaltrials.gov\/study\/NCT04396899\" target=\"_blank\" rel=\"nofollow noopener\">\uff08NCT04396899\uff09<\/a>The<sup>[2]<\/sup><\/p>\n<p><strong>\u5927\u962a\u5927\u5b66\uff1a<\/strong>\u4eba\u7c7b\uff08\u540c\u79cd\u5f02\u4f53\uff09iPS\u7ec6\u80de\u884d\u751f\u5fc3\u808c\u7ec6\u80de\u7247\u6cbb\u7597\u7f3a\u8840\u6027\u5fc3\u808c\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff08NCT04696328\uff09\u3002<\/p>\n<p><strong>\u5357\u4eac\u5927\u5b66\u533b\u5b66\u9662\uff1a<\/strong>\u4eba\u5fc3\u5916\u819c\u6ce8\u5c04\u540c\u79cd\u5f02\u4f53\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\u6765\u6e90\u7684\u5fc3\u808c\u7ec6\u80de\u6cbb\u7597\u7f3a\u8840\u6027\u5fc3\u529b\u8870\u7aed\u7684\u7814\u7a76\uff08\u300a\u5fc3\u810f\u75c5\u5b66\u6742\u5fd7\u300b\uff09\u3002<\/p>\n<p><strong>\u5171\u6d4e\u4f1a\u764c\u75c7\u4e2d\u5fc3\uff1a<\/strong>FT516\u6cbb\u75972019\u51a0\u72b6\u75c5\u6bd2\u75c5\uff08COVID-19\uff09\u4f4f\u9662\u7f3a\u6c27\u60a3\u8005\u7684\u5b89\u5168\u6027\u548c\u53ef\u884c\u6027\u7814\u7a76\uff08NCT04363346\uff09\u3002<\/p>\n<p><strong>\u4eac\u90fd\u5927\u5b66\u533b\u9662\uff1a<\/strong><\/p>\n<ul class=\"wp-block-list\">\n<li>\u4eac\u90fd\u8bd5\u9a8c\u8bc4\u4f30iPSC\u884d\u751f\u7684\u591a\u5df4\u80fa\u80fd\u7956\u7ec6\u80de\u5728\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u4e2d\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027 ( CiRA )<\/li>\n<\/ul>\n<ul class=\"wp-block-list\">\n<li>\u5c06\u81ea\u4f53iPS\u7ec6\u80de\u884d\u751f\u7684\u8840\u5c0f\u677f\u79fb\u690d\u7ed9\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u60a3\u8005\uff08CiRA\uff09\u7684\u4e34\u5e8a\u7814\u7a76<\/li>\n<\/ul>\n<p><strong>\u4eac\u90fd\u5927\u5b66\uff1a<\/strong>\u5bf9[18F]-GE180\u3001[18F]-FDOPA\u548c[18F]-FLT PET\u7814\u7a76\u8fdb\u884c\u5b9e\u7528\u8bc4\u4f30\uff0c\u4e3a\u672a\u6765\u57fa\u4e8eiPSC\u7684\u5e15\u91d1\u68ee\u75c5\u7ec6\u80de\u7597\u6cd5\u4e34\u5e8a\u8bd5\u9a8c\u505a\u51c6\u5907 ( UMIN-CTR\u2013UMIN000030084)\u3002<\/p>\n<p><strong>\u5e86\u5e94\u4e49\u587e\u5927\u5b66\uff1a<\/strong>\u5229\u7528iPS\u7ec6\u80de\u884d\u751f\u7684\u795e\u7ecf\u7956\u7ec6\u80de\u6cbb\u7597\u4e9a\u6025\u6027\u810a\u9ad3\u635f\u4f24\u7684\u518d\u751f\u533b\u5b66\uff08\u5e86\u5e94\u4e49\u587e\u5927\u5b66\uff09\u3002<\/p>\n<p><strong>\u795e\u6237\u5e02\u7acb\u773c\u79d1\u533b\u9662\uff1a<\/strong><\/p>\n<ul class=\"wp-block-list\">\n<li>\u540c\u79cd\u5f02\u4f53iPS\u7ec6\u80de\u6765\u6e90\u7684\u89c6\u7f51\u819c\u7247\u79fb\u690d\u6cbb\u7597\u89c6\u7f51\u819c\u8272\u7d20\u53d8\u6027\uff08\u795e\u6237\uff09\u3002<\/li>\n<li>\u540c\u79cd\u5f02\u4f53\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de (iPSC) \u884d\u751f\u7684\u89c6\u7f51\u819c\u8272\u7d20\u4e0a\u76ae (RPE) \u7ec6\u80de\u60ac\u6db2\u5728\u65b0\u751f\u8840\u7ba1\u6027\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u60a3\u8005\u4e2d\u7684\u79fb\u690d\u7814\u7a76( UMIN-CTR\u2013UMIN000026003 )\u3002<\/li>\n<\/ul>\n<p><strong>NIH\u4e34\u5e8a\u4e2d\u5fc3\uff1a<\/strong>\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\u6765\u6e90\u7684\u89c6\u7f51\u819c\u8272\u7d20\u4e0a\u76ae\u81ea\u4f53\u79fb\u690d\u6cbb\u7597\u4e0e\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u76f8\u5173\u7684\u5730\u56fe\u72b6\u840e\u7f29\u7684I\/IIa\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08NCT04339764\uff09\u3002<\/p>\n<p><strong>\u5fb7\u9ed1\u5170\u533b\u79d1\u5927\u5b66\uff1a<\/strong>\u4e00\u9879\u8bc4\u4f30\u81ea\u4f53\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\u6765\u6e90\u7684\u81ea\u7136\u6740\u4f24\u7ec6\u80de\u5728\u665a\u671f\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u60a3\u8005\u4e2a\u4f53\u5316\u6cbb\u7597\u4e2d\u7684\u4f5c\u7528\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff08IRCT20200429047241N1\uff09\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E5%9B%BD%E5%86%85%E6%B6%89%E5%8F%8A%E8%AF%B1%E5%AF%BC%E5%A4%9A%E8%83%BD%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\"><\/span><strong>\u56fd\u5185\u6d89\u53ca\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>\u5357\u4eac\u5927\u5b66\u533b\u5b66\u9662\uff1a<\/strong>\u4eba\u5fc3\u5916\u819c\u6ce8\u5c04\u540c\u79cd\u5f02\u4f53\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\u6765\u6e90\u7684\u5fc3\u808c\u7ec6\u80de\u6cbb\u7597\u7f3a\u8840\u6027\u5fc3\u529b\u8870\u7aed\u7684\u7814\u7a76\uff08\u300a\u5fc3\u810f\u75c5\u5b66\u6742\u5fd7\u300b\uff09\u3002<\/p>\n<figure class=\"wp-block-table is-style-stripes\">\n<table class=\"has-fixed-layout\">\n<thead>\n<tr>\n<th>\u75be\u75c5\u9886\u57df<\/th>\n<th>\u7ec6\u80de\u4ea7\u54c1\u540d\u79f0<\/th>\n<th>\u7814\u53d1\u673a\u6784\/\u516c\u53f8<\/th>\n<th>\u4e34\u5e8a\u9636\u6bb5<\/th>\n<th>\u7279\u70b9<\/th>\n<th>\u7275\u5934\/\u8054\u5408\u7814\u7a76\u5355\u4f4d<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>spinal cord injury<\/td>\n<td>\u672a\u63d0\u53ca\u540d\u79f0<\/td>\n<td>\u58eb\u6cfd\u751f\u7269<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">I\/II\u671f<\/span><\/span><\/td>\n<td>\u5168\u7403\u9996\u4e2a\u5f02\u4f53\u901a\u7528\u578b\u201d\u73b0\u8d27\u578b\u201diPSC\u884d\u751f\u4e9a\u578b\u795e\u7ecf\u7ec6\u80de<\/td>\n<td>\u4e2d\u5c71\u4e09\u9662\u3001\u5927\u8fde\u533b\u5927\u4e00\u9662<\/td>\n<\/tr>\n<tr>\n<td>Parkinson's disease<\/td>\n<td>XS411\u7ec6\u80de\u6ce8\u5c04\u6db2<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u58eb\u6cfd\u751f\u7269<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">I\/II\u671f<\/span><\/span><\/td>\n<td>\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u524d\u4f53\u7ec6\u80de\uff0c\u7acb\u4f53\u5b9a\u5411\u8111\u5185\u79fb\u690d<\/td>\n<td>\u672a\u660e\u786e<\/td>\n<\/tr>\n<tr>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Parkinson's disease<\/span><\/span><\/td>\n<td>NCR201\u6ce8\u5c04\u6db2<\/td>\n<td>\u4e2d\u76db\u6eaf\u6e90<\/td>\n<td>\u83b7\u6279\u4e34\u5e8a\u9ed8\u793a\u8bb8\u53ef<\/td>\n<td>iPSC\u884d\u751f\u7684\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u524d\u4f53\u7ec6\u80de\uff08iDAP\uff09<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u672a\u660e\u786e<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316<\/td>\n<td>XS228\u7ec6\u80de\u6ce8\u5c04\u6db2<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u58eb\u6cfd\u751f\u7269<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">I\/II\u671f<\/span><\/span><\/td>\n<td>iPSC\u6765\u6e90\u7684\u8fd0\u52a8\u795e\u7ecf\u7956\u7ec6\u80de\uff0c\u8170\u690e\u7a7f\u523a\u9798\u5185\u6ce8\u5c04<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u672a\u660e\u786e<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%E4%BA%AE%E7%82%B9\"><\/span><strong>\u4e34\u5e8a\u8bd5\u9a8c\u4eae\u70b9<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>\u810a\u9ad3\u635f\u4f24\uff1a<\/strong>\u5168\u7403\u9996\u4e2a\u9488\u5bf9\u810a\u9ad3\u635f\u4f24\u7684iPSC\u884d\u751f\u4e9a\u578b\u795e\u7ecf\u7ec6\u80de\u836f\u7269\uff08I\u7c7b\u65b0\u836f\uff09\u7684I\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u542f\u52a8\uff0c\u7531\u4e2d\u5c71\u5927\u5b66\u9644\u5c5e\u7b2c\u4e09\u533b\u9662\u548c\u5927\u8fde\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662\u8054\u5408\u5f00\u5c55\u3002\u8be5\u836f\u7269\u91c7\u7528\u201c\u73b0\u8d27\u578b\u201d\u8bbe\u8ba1\u3002<\/p>\n<p><strong>\u5e15\u91d1\u68ee\u75c5\uff1a<\/strong>\u58eb\u6cfd\u751f\u7269\u7684XS411\u7ec6\u80de\u6ce8\u5c04\u6db2\u65e8\u5728\u66ff\u4ee3\u53d7\u635f\u7684\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u3002<\/p>\n<p>\u4e2d\u76db\u6eaf\u6e90\u7684NCR201\u6ce8\u5c04\u6db2\u4e5f\u5df2\u83b7\u6279\u4e34\u5e8a\u9ed8\u793a\u8bb8\u53ef\uff0c\u5176\u516c\u5e03\u7684\u4e34\u5e8a\u6570\u636e\u663e\u793a\uff0c\u591a\u540d\u63a5\u53d7\u6cbb\u7597\u7684\u4e2d\u91cd\u5ea6\u5e15\u91d1\u68ee\u75c5\u60a3\u8005\u75c7\u72b6\u5f97\u5230\u529f\u80fd\u6027\u9006\u8f6c\uff0c\u4f8b\u5982\u4ece\u79fb\u690d\u524d\u7684\u751f\u6d3b\u4e0d\u80fd\u81ea\u7406\u6062\u590d\u5230\u80fd\u81ea\u5df1\u5403\u996d\u3001\u6d17\u6fa1\u3001\u5927\u6b65\u8d70\u3002<\/p>\n<p><strong>\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\uff08ALS\uff09\uff1a<\/strong>\u58eb\u6cfd\u751f\u7269\u7684XS228\u7ec6\u80de\u6ce8\u5c04\u6db2\u65e8\u5728\u4fee\u590d\u6216\u66ff\u4ee3\u53d7\u635f\u7684\u8fd0\u52a8\u795e\u7ecf\u5143\uff0c\u7ed9\u836f\u65b9\u5f0f\u4e3a\u8170\u690e\u7a7f\u523a\u9798\u5185\u6ce8\u5c04\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"4iPS%E7%BB%86%E8%83%9E%E6%8A%80%E6%9C%AF%E8%B5%84%E9%87%91\"><\/span><strong>4.iPS\u7ec6\u80de\u6280\u672f\u8d44\u91d1<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u9274\u4e8eiPSC\u6280\u672f\u7684\u5de8\u5927\u6f5c\u529b\uff0c\u5168\u7403\u8303\u56f4\u5185\u5bf9\u8be5\u7ec6\u80de\u7c7b\u578b\u7814\u7a76\u7684\u8d44\u52a9\u6b63\u5728\u52a0\u901f\u589e\u957f\u3002\u4f8b\u5982\uff0c\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\uff08NIH\uff09\u6bcf\u5e74\u6295\u8d4415\u4ebf\u7f8e\u5143\u7528\u4e8e\u5e72\u7ec6\u80de\u7814\u7a76\u9879\u76ee\uff0c\u6db5\u76d6\u4ece\u7ec6\u80de\u751f\u7269\u5b66\u5230\u7535\u5b50\u5de5\u7a0b\u7b49\u4f17\u591a\u9886\u57df\u3002\u7f8e\u56fd\u56fd\u5bb6\u5171\u6d4e\u5931\u8c03\u57fa\u91d1\u4f1a\uff08NAF\uff09\u4e5f\u4e00\u76f4\u5728\u9f13\u52b1\u7814\u7a76\u673a\u6784\u5f00\u5c55iPS\u7ec6\u80de\u7814\u7a76\u3002<\/p>\n<p>\u7f8e\u56fd\u591a\u4e2a\u5dde\u7684\u9879\u76ee\u4e5f\u4e3a\u5e72\u7ec6\u80de\u7814\u7a76\u9879\u76ee\u63d0\u4f9b\u4e86\u8d44\u91d1\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u52a0\u5dde\u518d\u751f\u533b\u5b66\u7814\u7a76\u6240\uff08CIRM\uff09\u6279\u51c6\u4e86\u4e00\u9879\u8ba1\u5212\uff0c\u5c06\u65a5\u8d4430\u4ebf\u7f8e\u5143\u652f\u6301\u5e72\u7ec6\u80de\u7814\u7a76\u3002\u5728\u5b66\u672f\u65b9\u9762\uff0c\u5723\u8def\u6613\u65af\u534e\u76db\u987f\u5927\u5b66\u533b\u5b66\u9662\u83b7\u5f97\u4e86\u5e93\u5947\u5bb6\u65cf\u9ad8\u8fbe1000\u4e07\u7f8e\u5143\u7684\u627f\u8bfa\uff0c\u7528\u4e8e\u652f\u6301\u63a8\u8fdb\u4e2a\u6027\u5316\u533b\u7597\u7684\u7814\u7a76\uff0c\u5305\u62ec\u652f\u6301\u8be5\u6821\u7684\u57fa\u56e0\u7ec4\u5de5\u7a0b\u548c\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u4e2d\u5fc3\u3002<\/p>\n<p>\u5728\u5168\u7403\u8303\u56f4\u5185\uff0c\u65e5\u672c\u653f\u5e9c\u5bf9iPS\u7ec6\u80de\u5c24\u4e3a\u9752\u7750\u3002\u65e5\u672c\u6587\u90e8\u79d1\u5b66\u7701\u5ba3\u5e03\uff0c\u8ba1\u5212\u5728\u672a\u6765\u5341\u5e74\u5185\u6295\u51651100\u4ebf\u65e5\u5143\uff08\u7ea6\u540811.3\u4ebf\u7f8e\u5143\uff09\u7528\u4e8eiPS\u7ec6\u80de\u7814\u7a76\u3002\u65e5\u672c\u56fd\u4f1a\u8fd8\u901a\u8fc7\u4e86\u4e00\u9879\u6cd5\u5f8b\uff0c\u547c\u5401\u65e5\u672c\u201c\u9886\u5148\u4e8e\u4e16\u754c\u5176\u4ed6\u56fd\u5bb6\u201d\uff0c\u8ba9\u56fd\u6c11\u80fd\u591f\u4eab\u53d7iPSC\u6280\u672f\u7b49\u518d\u751f\u533b\u5b66\u6cbb\u7597\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"5iPS%E7%BB%86%E8%83%9E%E5%95%86%E4%B8%9A%E5%8C%96\"><\/span><strong>5.iPS\u7ec6\u80de\u5546\u4e1a\u5316<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u81eaiPS\u7ec6\u80de\u88ab\u53d1\u73b0\u4ee5\u6765\uff0c\u4e00\u4e2a\u5e9e\u5927\u4e14\u84ec\u52c3\u53d1\u5c55\u7684\u7814\u7a76\u4ea7\u54c1\u5e02\u573a\u5df2\u7ecf\u5f62\u6210\uff0c\u8fd9\u4e3b\u8981\u662f\u56e0\u4e3a\u8fd9\u4e9b\u7ec6\u80de\u6ca1\u6709\u4e89\u8bae\uff0c\u5e76\u4e14\u53ef\u4ee5\u76f4\u63a5\u4ece\u6210\u4f53\u7ec6\u80de\u4e2d\u751f\u6210\u3002\u5982\u4eca\uff0c\u6709\u6570\u5341\u5bb6\u516c\u53f8\u63d0\u4f9biPS\u7ec6\u80de\u7cfb\u3001\u5206\u5316\u7ec6\u80de\u7c7b\u578b\u3001\u8bd5\u5242\u76d2\u3001\u68c0\u6d4b\u3001\u91cd\u7f16\u7a0b\u670d\u52a1\u7b49\u7b49\u3002<\/p>\n<p>\u9664\u4e86\u7814\u7a76\u5e94\u7528\u4e4b\u5916\uff0c\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de (iPS \u7ec6\u80de) \u8fd8\u53ef\u7528\u4e8e\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li>\u836f\u7269\u7b5b\u9009<\/li>\n<li>\u6bd2\u7406\u5b66\u7814\u7a76<\/li>\n<li>\u75be\u75c5\u5efa\u6a21<\/li>\n<li>\u7ec6\u80de\u7597\u6cd5<\/li>\n<li>\u4e2a\u6027\u5316\u533b\u7597<\/li>\n<li>\u5de5\u4e1a\u89c4\u6a21\u5236\u9020<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"6%E5%A6%82%E4%BD%95%E7%9C%8B%E5%BE%85iPSC%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%EF%BC%9F\"><\/span><strong>6.\u5982\u4f55\u770b\u5f85iPSC\u4e34\u5e8a\u8bd5\u9a8c\uff1f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>iPSC\u6280\u672f\u4e3a\u8bb8\u591a\u96be\u6cbb\u6027\u75be\u75c5\u5e26\u6765\u4e86\u65b0\u7684\u5e0c\u671b\uff0c\u5c24\u5176\u662f\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u3001\u4ee3\u8c22\u6027\u75be\u75c5\u7b49\u3002\u56fd\u5185\u7684\u7814\u53d1\u8fdb\u5c55\u4e5f\u975e\u5e38\u8fc5\u901f\u3002\u4e0d\u8fc7\uff0c\u9700\u8981\u6ce8\u610f\u7684\u662f\uff1a<\/p>\n<p><strong>\u591a\u6570\u5904\u4e8e\u65e9\u671f\u9636\u6bb5\uff1a<\/strong>\u76ee\u524d\u5927\u591a\u4e34\u5e8a\u8bd5\u9a8c\u5904\u4e8eI\u671f\u6216II\u671f\uff0c\u4e3b\u8981\u76ee\u7684\u662f\u8bc4\u4f30\u5b89\u5168\u6027\u548c\u521d\u6b65\u6709\u6548\u6027\uff0c\u8ddd\u79bb\u5e7f\u6cdb\u5e94\u7528\u4ecd\u9700\u65f6\u95f4\u3002<\/p>\n<p><strong>\u4ece\u201c\u81ea\u4f53\u201d\u5230\u201c\u5f02\u4f53\u901a\u7528\u578b\u201d\uff1a<\/strong>iPSC\u7597\u6cd5\u6709\u81ea\u4f53\uff08\u7528\u81ea\u5df1\u7684\u7ec6\u80de\uff09\u548c\u5f02\u4f53\uff08\u4f7f\u7528\u6765\u81ea\u5065\u5eb7\u4f9b\u4f53\u7684\u7ec6\u80de\u7cfb\uff09\u4e4b\u5206\u3002\u201c\u73b0\u8d27\u578b\u201d\u5f02\u4f53\u901a\u7528\u578b\u4ea7\u54c1\uff08\u5982\u8868\u4e2d\u7684\u810a\u9ad3\u635f\u4f24\u9879\u76ee\uff09\u662f\u91cd\u8981\u53d1\u5c55\u65b9\u5411\uff0c\u5b83\u610f\u5473\u7740\u7ec6\u80de\u836f\u7269\u53ef\u4ee5\u50cf\u4f20\u7edf\u836f\u7269\u4e00\u6837\u6279\u91cf\u751f\u4ea7\u3001\u50a8\u5b58\u548c\u4f7f\u7528\uff0c\u66f4\u80fd\u89e3\u51b3\u53ef\u53ca\u6027\u548c\u6210\u672c\u95ee\u9898\u3002<\/p>\n<p><strong>\u7406\u6027\u770b\u5f85\uff1a<\/strong>\u79d1\u5b66\u63a2\u7d22\u6b65\u6b65\u4e3a\u8425\uff0c\u6210\u679c\u4ee4\u4eba\u9f13\u821e\uff0c\u4f46\u4e5f\u8981\u5bf9\u7814\u53d1\u8fc7\u7a0b\u7684\u957f\u671f\u6027\u548c\u4e25\u8c28\u6027\u6709\u5408\u7406\u9884\u671f\u3002<\/p>\n<p>\u56fd\u5185iPSC\u7684\u4e34\u5e8a\u7814\u7a76\u6b63\u5728\u5feb\u901f\u53d1\u5c55\uff0c\u4e3b\u8981\u96c6\u4e2d\u5728\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u7b49\u9886\u57df\uff0c\u5e76\u5c1d\u8bd5\u5f00\u53d1\u201c\u73b0\u8d27\u578b\u201d\u7ec6\u80de\u836f\u7269\u3002\u79d1\u5b66\u5bb6\u4eec\u5e0c\u671b\u8fd9\u4e9b\u52aa\u529b\u6700\u7ec8\u80fd\u4e3a\u8bb8\u591a\u76ee\u524d\u7f3a\u4e4f\u6709\u6548\u6cbb\u7597\u65b9\u6cd5\u7684\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u9009\u62e9\u3002<\/p>\n<blockquote><p>References:<\/p>\n<p>\u4e3b\u8981\u4fe1\u606f\u53c2\u8003\u6765\u6e90\uff1aBioInformant<\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[1]https:\/\/announcements.asx.com.au\/asxpdf\/20200618\/pdf\/44jr653pvmxxx3.pdf<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[2] <\/span><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">https:\/\/clinicaltrials.gov\/study\/NCT04396899<\/span><\/span><\/p>\n<p>Disclaimer: This article is intended only to disseminate scientific knowledge and share industry perspectives, and does not constitute any clinical diagnostic advice! The information published by Hangi Stem Cells is not a substitute for the professional advice of a physician or pharmacist. If you have any questions about copyright or other issues, please feel free to contact me.<\/p><\/blockquote>","protected":false},"excerpt":{"rendered":"<p>\u4ec0\u4e48\u662f\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\uff1f\u672c\u6587\u7cfb\u7edf\u4ecb\u7ecdiPSC\u7684\u53d1\u73b0\u3001\u7279\u70b9\u53ca\u4e0e\u80da\u80ce\u5e72\u7ec6\u80de\u7684\u533a\u522b\uff0c\u5e76\u76d8\u70b9\u5168\u7403\u53ca\u56fd\u5185\u6b63\u5728\u8fdb\u884c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u5c55\u3002\u5185\u5bb9\u6db5\u76d6iPSC\u5728\u5e15\u91d1\u68ee\u75c5\u3001\u5fc3\u810f\u75c5\u3001\u7cd6\u5c3f\u75c5\u7b49\u75be\u75c5\u4e2d\u7684\u5e94\u7528\u524d\u666f\u53ca\u79d1\u7814\u8d44\u91d1\u6765\u6e90\uff0c\u5e2e\u52a9\u8bfb\u8005\u5168\u9762\u4e86\u89e3iPSC\u6280\u672f\u3001\u4e34\u5e8a\u8bd5\u9a8c\u65b9\u5411\u4e0e\u5546\u4e1a\u5316\u8d8b\u52bf\u3002<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[75],"tags":[193,172],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/19875"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/comments?post=19875"}],"version-history":[{"count":1,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/19875\/revisions"}],"predecessor-version":[{"id":19876,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/19875\/revisions\/19876"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media?parent=19875"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/categories?post=19875"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/tags?post=19875"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}