{"id":20130,"date":"2025-10-28T18:54:39","date_gmt":"2025-10-28T10:54:39","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=20130"},"modified":"2025-10-28T18:54:39","modified_gmt":"2025-10-28T10:54:39","slug":"%e8%84%82%e8%82%aa%e5%b9%b2%e7%bb%86%e8%83%9e%e6%b2%bb%e7%96%97%e7%b3%96%e5%b0%bf%e7%97%85","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html","title":{"rendered":"\u8102\u80aa\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u53ca\u5176\u5e76\u53d1\u75c7\u4e2d\u7684\u8fdb\u5c55\u53ca\u5e94\u7528"},"content":{"rendered":"<p><a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/19950.html\/\" target=\"_blank\" rel=\"noopener\">\u7cd6\u5c3f\u75c5\uff08DM\uff09<\/a>\u662f\u4e00\u79cd\u4e25\u91cd\u7684\u6162\u6027\u4ee3\u8c22\u6027\u75be\u75c5\uff0c\u5e38\u5f15\u53d1\u5fc3\u8840\u7ba1\u75be\u75c5\u3001\u89c6\u7f51\u819c\u75c5\u53d8\u3001\u795e\u7ecf\u75c5\u53d8\u548c\u80be\u810f\u75be\u75c5\u7b49\u4e25\u91cd\u5e76\u53d1\u75c7\u3002\u60a3\u8005\u786e\u8bca\u540e\u9700\u957f\u671f\u4f9d\u8d56\u53e3\u670d\u964d\u7cd6\u836f\u6216\u80f0\u5c9b\u7d20\u4ee5\u63a7\u5236\u8840\u7cd6\u3001\u5ef6\u7f13\u75c5\u60c5\uff0c\u8fd9\u4e0d\u4ec5\u4e25\u91cd\u5f71\u54cd\u65e5\u5e38\u751f\u6d3b\u3001\u9700\u6301\u7eed\u76d1\u6d4b\u836f\u7269\u526f\u4f5c\u7528\uff0c\u4e5f\u4e3a\u60a3\u8005\u3001\u5bb6\u5ead\u53ca\u793e\u4f1a\u5e26\u6765\u4e86\u6c89\u91cd\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20144 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-1717835797-612x612-1.jpg\" 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class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#%E8%84%82%E8%82%AA%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B3%96%E5%B0%BF%E7%97%85%E5%8F%8A%E5%85%B6%E5%B9%B6%E5%8F%91%E7%97%87%E4%B8%AD%E7%9A%84%E8%BF%9B%E5%B1%95%E5%8F%8A%E5%BA%94%E7%94%A8\" >\u8102\u80aa\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u53ca\u5176\u5e76\u53d1\u75c7\u4e2d\u7684\u8fdb\u5c55\u53ca\u5e94\u7528<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#%E4%BB%80%E4%B9%88%E6%98%AF%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%8C%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E7%89%B9%E7%82%B9%E5%8F%8A%E4%BC%98%E5%8A%BF%EF%BC%8C%E5%8F%8A%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E5%9C%A8%E6%B2%BB%E7%96%972%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E7%9A%84%E4%BC%98%E5%8A%BF%E5%8F%8A%E7%89%B9%E7%82%B9\" >\u4ec0\u4e48\u662f\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff0c\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7279\u70b9\u53ca\u4f18\u52bf\uff0c\u53ca\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5728\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u7684\u4f18\u52bf\u53ca\u7279\u70b9<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#1_%E4%BB%80%E4%B9%88%E6%98%AF%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88ADSCs%EF%BC%89%EF%BC%9F\" >1. \u4ec0\u4e48\u662f\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08ADSCs\uff09\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#2_%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88ADSCs%EF%BC%89%E7%9A%84%E7%89%B9%E7%82%B9%E5%8F%8A%E4%BC%98%E5%8A%BF\" >2. \u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08ADSCs\uff09\u7684\u7279\u70b9\u53ca\u4f18\u52bf<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#3_%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E5%9C%A8%E6%B2%BB%E7%96%972%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E4%B8%AD%E7%9A%84%E4%BC%98%E5%8A%BF%E5%8F%8A%E7%89%B9%E7%82%B9\" >3. \u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5728\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u4e2d\u7684\u4f18\u52bf\u53ca\u7279\u70b9<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#ADSCs%E5%9C%A81%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E4%B8%AD%E7%9A%84%E5%BA%94%E7%94%A8\" >ADSCs\u57281\u578b\u7cd6\u5c3f\u75c5\u4e2d\u7684\u5e94\u7528<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%971%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E7%9A%84%E4%BA%BA%E4%BD%93%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\" >\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u75971\u578b\u7cd6\u5c3f\u75c5\u7684\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%971%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E7%9A%84%E4%B8%89%E5%A4%A7%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\" >\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u75971\u578b\u7cd6\u5c3f\u75c5\u7684\u4e09\u5927\u4f5c\u7528\u673a\u5236<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#ADSCs%E5%9C%A82%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E4%B8%AD%E7%9A%84%E5%BA%94%E7%94%A8\" >ADSCs\u57282\u578b\u7cd6\u5c3f\u75c5\u4e2d\u7684\u5e94\u7528<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%972%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E7%9A%84%E4%B8%89%E5%A4%A7%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\" >\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u7684\u4e09\u5927\u4f5c\u7528\u673a\u5236<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E5%9C%A8%E7%B3%96%E5%B0%BF%E7%97%85%E5%B9%B6%E5%8F%91%E7%97%87%E4%B8%AD%E7%9A%84%E5%BA%94%E7%94%A8\" >\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5728\u7cd6\u5c3f\u75c5\u5e76\u53d1\u75c7\u4e2d\u7684\u5e94\u7528<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B3%96%E5%B0%BF%E7%97%85%E4%BC%A4%E5%8F%A3%E4%B8%AD%E7%9A%84%E5%BA%94%E7%94%A8\" >\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u4f24\u53e3\u4e2d\u7684\u5e94\u7528<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B3%96%E5%B0%BF%E7%97%85%E8%A7%86%E7%BD%91%E8%86%9C%E7%97%85%E5%8F%98%E7%9A%84%E5%BA%94%E7%94%A8\" >\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u75c5\u53d8\u7684\u5e94\u7528<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B3%96%E5%B0%BF%E7%97%85%E8%82%BE%E7%97%85%E7%9A%84%E5%BA%94%E7%94%A8\" >\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u80be\u75c5\u7684\u5e94\u7528<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20130.html\/#%E7%BB%93%E8%AE%BA\" >reach a verdict<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%E8%84%82%E8%82%AA%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B3%96%E5%B0%BF%E7%97%85%E5%8F%8A%E5%85%B6%E5%B9%B6%E5%8F%91%E7%97%87%E4%B8%AD%E7%9A%84%E8%BF%9B%E5%B1%95%E5%8F%8A%E5%BA%94%E7%94%A8\"><\/span>\u8102\u80aa\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u53ca\u5176\u5e76\u53d1\u75c7\u4e2d\u7684\u8fdb\u5c55\u53ca\u5e94\u7528<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5728\u6b64\u80cc\u666f\u4e0b\uff0c<strong>\u8102\u80aa\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5<\/strong>\u5c55\u73b0\u4e86\u5de8\u5927\u7684\u6f5c\u529b\u3002\u5e72\u7ec6\u80de\u51ed\u501f\u5176\u81ea\u6211\u66f4\u65b0\u3001\u591a\u5411\u5206\u5316\u53ca\u514d\u75ab\u8c03\u8282\u80fd\u529b\uff0c\u4e3a\u591a\u79cd\u75be\u75c5\u63d0\u4f9b\u4e86\u65b0\u7684\u6cbb\u7597\u7b56\u7565\u3002\u5176\u4e2d\uff0c\u8102\u80aa\u5e72\u7ec6\u80de\uff08ADSC\uff09\u56e0\u5176\u6765\u6e90\u5e7f\u6cdb\uff08\u5982\u8179\u90e8\u3001\u56db\u80a2\u7b49\uff09\u3001\u83b7\u53d6\u4fbf\u6377\u4e14\u5bf9\u673a\u4f53\u635f\u4f24\u5c0f\uff0c\u76f8\u8f83\u4e8e\u5176\u4ed6\u5e72\u7ec6\u80de\u66f4\u5177\u5e94\u7528\u4f18\u52bf\u3002\u76ee\u524d\uff0cADSC\u5df2\u5728\u7cd6\u5c3f\u75c5\u52a8\u7269\u6a21\u578b\u6cbb\u7597\u4e2d\u53d6\u5f97\u6210\u6548\uff0c\u90e8\u5206\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\uff08I\/II\u671f\uff09\u4e5f\u5df2\u5f00\u5c55\uff0c\u5c11\u6570\u751a\u81f3\u8fdb\u5165III\u671f\u8bd5\u9a8c\u9636\u6bb5\u3002\u672c\u6587\u5c06\u91cd\u70b9\u7efc\u8ff0<a href=\"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-023-03620-0#Fig1\" target=\"_blank\" rel=\"noopener nofollow\"><strong>\u8102\u80aa\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5<\/strong>\u53ca\u5176\u5e76\u53d1\u75c7\u7684\u7814\u7a76\u8fdb\u5c55\uff0c\u5e76\u6df1\u5165\u63a2\u8ba8\u5176\u6f5c\u5728\u7684\u4f5c\u7528\u673a\u5236<\/a>The<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20145 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_181555_346.png\" alt=\"\u8102\u80aa\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u53ca\u5176\u5e76\u53d1\u75c7\u4e2d\u7684\u8fdb\u5c55\u53ca\u5e94\u7528\" width=\"780\" height=\"386\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_181555_346.png 780w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_181555_346-300x148.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_181555_346-768x380.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_181555_346-18x9.png 18w\" sizes=\"(max-width: 780px) 100vw, 780px\" \/><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%BB%80%E4%B9%88%E6%98%AF%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%8C%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E7%89%B9%E7%82%B9%E5%8F%8A%E4%BC%98%E5%8A%BF%EF%BC%8C%E5%8F%8A%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E5%9C%A8%E6%B2%BB%E7%96%972%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E7%9A%84%E4%BC%98%E5%8A%BF%E5%8F%8A%E7%89%B9%E7%82%B9\"><\/span>\u4ec0\u4e48\u662f\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff0c\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7279\u70b9\u53ca\u4f18\u52bf\uff0c\u53ca\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5728\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u7684\u4f18\u52bf\u53ca\u7279\u70b9<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"1_%E4%BB%80%E4%B9%88%E6%98%AF%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88ADSCs%EF%BC%89%EF%BC%9F\"><\/span>1. \u4ec0\u4e48\u662f\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08ADSCs\uff09\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\">\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08ADSCs\uff09\u662f\u4e00\u7c7b\u5b58\u5728\u4e8e\u8102\u80aa\u7ec4\u7ec7\u4e2d\u7684<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/19927.html\/\" target=\"_blank\" rel=\"noopener\">Mesenchymal Stem Cells (MSC)<\/a>\u3002\u5b83\u4eec\u5177\u6709\u81ea\u6211\u66f4\u65b0\u548c\u591a\u5411\u5206\u5316\u7684\u6f5c\u80fd\uff0c\u80fd\u591f\u5728\u4e00\u5b9a\u6761\u4ef6\u4e0b\u5206\u5316\u6210\u591a\u79cd\u7ec6\u80de\u7c7b\u578b\uff0c\u5982\u8102\u80aa\u7ec6\u80de\u3001\u6210\u9aa8\u7ec6\u80de\u548c\u8f6f\u9aa8\u7ec6\u80de\u7b49\u3002\u4e0e\u5176\u4ed6\u6765\u6e90\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08\u5982\u9aa8\u9ad3\u6765\u6e90BM-MSC\uff09\u76f8\u6bd4\uff0cADSCs\u62e5\u6709\u76f8\u4f3c\u7684\u589e\u6b96\u548c\u5206\u5316\u80fd\u529b\uff0c\u4f46\u5176\u83b7\u53d6\u65b9\u5f0f\u66f4\u4e3a\u4fbf\u6377\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"2_%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88ADSCs%EF%BC%89%E7%9A%84%E7%89%B9%E7%82%B9%E5%8F%8A%E4%BC%98%E5%8A%BF\"><\/span>2. \u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08ADSCs\uff09\u7684\u7279\u70b9\u53ca\u4f18\u52bf<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\">ADSCs\u4e4b\u6240\u4ee5\u6210\u4e3a\u7ec6\u80de\u6cbb\u7597\u7684\u4f18\u9009\u6765\u6e90\uff0c\u4e3b\u8981\u5f52\u529f\u4e8e\u4ee5\u4e0b\u51e0\u5927\u7279\u70b9\u548c\u4f18\u52bf\uff1a<\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u6765\u6e90\u4e30\u5bcc\uff0c\u6613\u4e8e\u83b7\u53d6<\/strong>\uff1aADSCs\u53ef\u4ee5\u4ece\u8102\u80aa\u7ec4\u7ec7\u4e2d\u5927\u91cf\u83b7\u5f97\uff0c\u901a\u5e38\u901a\u8fc7\u62bd\u8102\u672f\u7b49\u5e38\u89c4\u7f8e\u5bb9\u5916\u79d1\u624b\u672f\u5373\u53ef\u83b7\u53d6\uff0c\u5bf9\u4f9b\u4f53\u635f\u4f24\u5c0f\uff0c\u907f\u514d\u4e86\u9aa8\u9ad3\u63d0\u53d6\u7684\u5267\u75db\u548c\u611f\u67d3\u98ce\u9669\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u589e\u6b96\u80fd\u529b\u5f3a\uff0c\u57f9\u517b\u65f6\u95f4\u8f83\u957f<\/strong>\uff1aADSCs\u5728\u4f53\u5916\u8868\u73b0\u51fa\u8f83\u5f3a\u7684\u589e\u6b96\u80fd\u529b\uff0c\u53ef\u4ee5\u5728\u57f9\u517b\u4e2d\u7ef4\u6301\u8f83\u957f\u65f6\u95f4\uff0c\u4e3a\u4e34\u5e8a\u6cbb\u7597\u63d0\u4f9b\u4e86\u5145\u8db3\u7684\u7ec6\u80de\u6570\u91cf\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u514d\u75ab\u8868\u578b\u660e\u786e<\/strong>\uff1aADSCs\u8868\u8fbe\u5178\u578b\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u8868\u9762\u6807\u5fd7\u7269\uff08\u5982CD29, CD44, CD73, CD105\u7b49\uff09\uff0c\u5e76\u4e14\u4e0d\u8868\u8fbe\u9020\u8840\u7ec6\u80de\u6807\u5fd7\u7269\uff08\u5982CD45, CD34\uff09\u3002\u5176\u4e2dCD36\u548cCD49d\u88ab\u8ba4\u4e3a\u662fADSCs\u6240\u7279\u6709\u7684\u6807\u5fd7\u7269\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u5b89\u5168\u6027\u8f83\u9ad8<\/strong>\uff1a\u591a\u6570\u7814\u7a76\u8868\u660e\uff0cADSCs\u5177\u6709\u9057\u4f20\u548c\u8868\u89c2\u9057\u4f20\u7a33\u5b9a\u6027\uff0c\u672a\u8868\u73b0\u51fa\u660e\u663e\u7684\u514d\u75ab\u6392\u65a5\u53cd\u5e94\u548c\u81f4\u7624\u6027\uff0c\u5728\u52a8\u7269\u6a21\u578b\u548c\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5747\u663e\u793a\u51fa\u826f\u597d\u7684\u5b89\u5168\u6027\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u591a\u91cd\u4fee\u590d\u673a\u5236<\/strong>\uff1aADSCs\u80fd\u591f\u5206\u6ccc\u591a\u79cd\u4fee\u590d\u6027\u5206\u5b50\uff0c\u5305\u62ec\u795e\u7ecf\u8425\u517b\u56e0\u5b50\u3001\u8d8b\u5316\u56e0\u5b50\u3001\u514d\u75ab\u8c03\u8282\u56e0\u5b50\u548c\u708e\u75c7\u8c03\u8282\u56e0\u5b50\uff0c\u901a\u8fc7\u8fd9\u4e9b\u56e0\u5b50\u53c2\u4e0e\u7ec4\u7ec7\u4fee\u590d\u548c\u529f\u80fd\u8c03\u8282\u3002<\/p>\n<\/li>\n<\/ul>\n<h3><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20143 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-2088871772-612x612-1.jpg\" alt=\"\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u53ca\u5e76\u53d1\u75c7\" width=\"612\" height=\"344\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-2088871772-612x612-1.jpg 612w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-2088871772-612x612-1-300x169.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-2088871772-612x612-1-18x10.jpg 18w\" sizes=\"(max-width: 612px) 100vw, 612px\" \/><\/h3>\n<h3><span class=\"ez-toc-section\" id=\"3_%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E5%9C%A8%E6%B2%BB%E7%96%972%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E4%B8%AD%E7%9A%84%E4%BC%98%E5%8A%BF%E5%8F%8A%E7%89%B9%E7%82%B9\"><\/span>3. \u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5728\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u4e2d\u7684\u4f18\u52bf\u53ca\u7279\u70b9<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\">\u57282\u578b\u7cd6\u5c3f\u75c5\u7684\u6cbb\u7597\u4e2d\uff0cADSCs\u9664\u4e86\u5177\u5907\u4e0a\u8ff0\u901a\u7528\u4f18\u52bf\u5916\uff0c\u8fd8\u5c55\u73b0\u51fa\u4ee5\u4e0b\u9488\u5bf9\u6027\u7684\u6cbb\u7597\u6f5c\u529b\u548c\u7279\u70b9\uff1a<\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u6539\u5584\u80f0\u5c9b\u529f\u80fd\u4e0e\u80f0\u5c9b\u7d20\u654f\u611f\u6027<\/strong>\uff1a\u57fa\u4e8e\u5176\u4ed6\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08\u5982BM-MSC\uff09\u7684\u7814\u7a76\u5df2\u8bc1\u5b9e\uff0c\u6b64\u7c7b\u7ec6\u80de\u80fd\u51cf\u5c11\u60a3\u8005\u80f0\u5c9b\u7d20\u9700\u6c42\u3001\u589e\u52a0\u80f0\u5c9b\u7d20\u654f\u611f\u6027\u5e76\u6539\u5584\u03b2\u7ec6\u80de\u529f\u80fd\u3002\u4f5c\u4e3a\u4f18\u79c0\u7684\u66ff\u4ee3\u6765\u6e90\uff0cADSCs\u6709\u671b\u7ee7\u627f\u5e76\u5b9e\u73b0\u8fd9\u4e9b\u7597\u6548\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u5f3a\u5927\u7684\u514d\u75ab\u4e0e\u708e\u75c7\u8c03\u8282\u80fd\u529b<\/strong>\uff1a2\u578b\u7cd6\u5c3f\u75c5\u5e38\u4f34\u968f\u6162\u6027\u708e\u75c7\u548c\u514d\u75ab\u7d0a\u4e71\u3002ADSCs\u5206\u6ccc\u7684\u514d\u75ab\u8c03\u8282\u56e0\u5b50\u548c\u708e\u75c7\u8c03\u8282\u56e0\u5b50\u80fd\u591f\u8c03\u8282\u673a\u4f53\u514d\u75ab\u72b6\u6001\uff08\u4f8b\u5982\u63d0\u5347\u8c03\u8282\u6027T\u7ec6\u80de\u6c34\u5e73\uff09\uff0c\u6709\u52a9\u4e8e\u63a7\u5236\u7cd6\u5c3f\u75c5\u76f8\u5173\u7684\u708e\u75c7\u53cd\u5e94\uff0c\u4ece\u6839\u672c\u4e0a\u6539\u5584\u80f0\u5c9b\u7d20\u62b5\u6297\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u6f5c\u5728\u7684\u7ec6\u80de\u4fee\u590d\u4e0e\u66ff\u4ee3\u4f5c\u7528<\/strong>\uff1a\u52a8\u7269\u6a21\u578b\u9a8c\u8bc1\uff0c\u79fb\u690d\u7684ADSCs\u4e0d\u4ec5\u80fd\u5728\u4f53\u5185\u5206\u5316\u5e76\u6574\u5408\uff0c\u8fd8\u53ef\u80fd\u901a\u8fc7\u5176\u5206\u6ccc\u7684\u591a\u79cd\u4fee\u590d\u5206\u5b50\uff0c\u76f4\u63a5\u6216\u95f4\u63a5\u5730\u4fc3\u8fdb\u53d7\u635f\u7ec4\u7ec7\uff08\u5982\u80f0\u5c9b\u3001\u80be\u810f\u3001\u5fc3\u810f\uff09\u7684\u4fee\u590d\uff0c\u8fd9\u5bf9\u4e8e\u9632\u6cbb\u7cd6\u5c3f\u75c5\u5e76\u53d1\u75c7\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u89c4\u907f\u4f26\u7406\u95ee\u9898<\/strong>\uff1a\u4e0e\u80ce\u513f\u9644\u5c5e\u7269\uff08\u5982\u8110\u5e26\u3001\u80ce\u76d8\uff09\u6765\u6e90\u7684MSCs\u4e0d\u540c\uff0cADSCs\u6765\u81ea\u6210\u4eba\u81ea\u4f53\u8102\u80aa\u7ec4\u7ec7\uff0c\u4e0d\u5b58\u5728\u76f8\u5173\u7684\u4f26\u7406\u4e89\u8bae\uff0c\u4f7f\u5176\u4e34\u5e8a\u8f6c\u5316\u8def\u5f84\u66f4\u4e3a\u987a\u7545\u3002<\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\">\u7efc\u4e0a\u6240\u8ff0\uff0c<strong>\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08ADSCs\uff09\u51ed\u501f\u5176\u6613\u83b7\u53d6\u3001\u5b89\u5168\u6027\u9ad8\u3001\u517c\u5177\u6539\u5584\u80f0\u5c9b\u529f\u80fd\u548c\u8c03\u8282\u514d\u75ab\/\u708e\u75c7\u7684\u53cc\u91cd\u6f5c\u529b\uff0c\u6210\u4e3a\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u53ca\u5176\u5e76\u53d1\u75c7\u7684\u4e00\u79cd\u6781\u5177\u524d\u666f\u7684\u7ec6\u80de\u6cbb\u7597\u9009\u62e9\u3002<\/strong><\/p>\n<h2 id=\"Sec3\" class=\"c-article-section__title js-section-title js-c-reading-companion-sections-item\"><span class=\"ez-toc-section\" id=\"ADSCs%E5%9C%A81%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E4%B8%AD%E7%9A%84%E5%BA%94%E7%94%A8\"><\/span><span dir=\"auto\">ADSCs\u57281\u578b\u7cd6\u5c3f\u75c5\u4e2d\u7684\u5e94\u7528<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<div id=\"Sec3-content\" class=\"c-article-section__content\">\n<p><span dir=\"auto\">\u5728 1 \u578b\u7cd6\u5c3f\u75c5\u4e2d\uff0c\u7531\u4e8e\u81ea\u8eab\u514d\u75ab\u53cd\u5e94\uff0c\u8f85\u52a9\u6027 T \u7ec6\u80de 1 (Th1) \u653b\u51fb\u80f0\u817a \u03b2 \u7ec6\u80de\uff0c\u5bfc\u81f4\u80f0\u5c9b\u7d20\u5206\u6ccc\u7ec6\u80de (IPC) \u7684\u635f\u5931<\/span><span dir=\"auto\">\u3002\u5de8\u566c\u7ec6\u80de\u3001\u6811\u7a81\u72b6\u7ec6\u80de\u3001\u81ea\u7136\u6740\u4f24\u7ec6\u80de\u548c\u6dcb\u5df4\u7ec6\u80de\u7684\u5b58\u5728\u4e5f\u4f1a\u52a0\u901f 1 \u578b\u7cd6\u5c3f\u75c5\u7684\u8fdb\u5c55<\/span><span dir=\"auto\">\u3002CD4<\/span><sup><span dir=\"auto\">+<\/span><\/sup><span dir=\"auto\"> T \u7ec6\u80de\u548c\u708e\u75c7\u56e0\u5b50\uff0c\u5305\u62ec\u5e72\u6270\u7d20-\u03b3 (IFN-\u03b3)\u3001\u767d\u7ec6\u80de\u4ecb\u7d20-2 (IL-2) \u548c\u80bf\u7624\u574f\u6b7b\u56e0\u5b50-\u03b1 (TNF-\u03b1)\uff0c\u5728 \u03b2 \u7ec6\u80de\u635f\u4f24\u8fc7\u7a0b\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528<\/span><span dir=\"auto\">\u3002\u7531\u4e8e\u80f0\u817a\u03b2\u7ec6\u80de\u662f\u4f53\u5185\u552f\u4e00\u7684\u80f0\u5c9b\u7d20\u4ea7\u751f\u7ec6\u80de\uff0c\u5b83\u4eec\u7684\u6b7b\u4ea1\u4f1a\u5bfc\u81f4\u80f0\u5c9b\u7d20\u5206\u6ccc\u5b8c\u5168\u505c\u6b62\uff0c\u6700\u7ec8\u5bfc\u81f4\u7cd6\u5c3f\u75c5\u7684\u53d1\u5c55<\/span><span dir=\"auto\">The<\/span><\/p>\n<p><span dir=\"auto\">\u76ee\u524d\u7684\u5e72\u9884\u63aa\u65bd\u65e0\u6cd5\u9884\u9632\u8840\u7ba1\u9000\u5316\u3001\u80be\u8870\u7aed\u3001\u5931\u660e\u7b49\u957f\u671f\u5e76\u53d1\u75c7\u3002\u4e34\u5e8a\u4e0a\u5df2\u5e94\u7528\u7684\u03b2\u7ec6\u80de\u66ff\u4ee3\u65b9\u6cd5\u4e3b\u8981\u6709\u5168\u80f0\u817a\u548c\u80f0\u5c9b\u7ec6\u80de\u79fb\u690d<\/span><span dir=\"auto\">\u3002\u7136\u800c\uff0c\u8fd9\u4e9b\u65b9\u6cd5\u7684\u53d1\u5c55\u4ecd\u9762\u4e34\u8bf8\u591a\u969c\u788d\uff0c\u5982\u7f3a\u4e4f\u5408\u9002\u7684\u80f0\u5c9b\u4f9b\u4f53\u3001\u79fb\u690d\u540e\u9700\u8981\u7ec8\u751f\u514d\u75ab\u6291\u5236\u6cbb\u7597\u3001\u7cd6\u5c3f\u75c5\u60a3\u8005\u79fb\u690d\u5668\u5b98\u548c\u7ec6\u80de\u8017\u7aed\u7b49\uff0c\u8fd9\u4e9b\u90fd\u5236\u7ea6\u4e86\u8be5\u6280\u672f\u7684\u53d1\u5c55<\/span><span dir=\"auto\">\u3002\u8fd1\u5e74\u6765\uff0cADSCs\u56e0\u5176\u5177\u6709\u81ea\u6211\u66f4\u65b0\u3001\u5206\u5316\u4e3a\u5176\u4ed6\u7ec6\u80de\u8c31\u7cfb\u4ee5\u53ca\u8c03\u8282\u514d\u75ab\u7cfb\u7edf\u7684\u80fd\u529b\uff0c\u9010\u6e10\u53d7\u5230\u7814\u7a76\u8005\u7684\u5173\u6ce8\uff0c\u5e0c\u671b\u5229\u7528ADSCs\u7684\u7279\u6027\u6765\u8fbe\u5230\u6cbb\u61081\u578b\u7cd6\u5c3f\u75c5\u7684\u76ee\u7684\u3002<\/span><\/p>\n<h2 id=\"Sec4\" class=\"c-article-section__title js-section-title js-c-reading-companion-sections-item\"><span class=\"ez-toc-section\" id=\"%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%971%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E7%9A%84%E4%BA%BA%E4%BD%93%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C\"><\/span><span dir=\"auto\">\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u75971\u578b\u7cd6\u5c3f\u75c5\u7684\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/div>\n<p><span dir=\"auto\">\u76ee\u524d\uff0c ADSCs\u7528\u4e8e\u6cbb\u75971\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u5c1a\u5904\u4e8e\u521d\u6b65\u7814\u7a76\u9636\u6bb5\uff0c\u76f8\u5173<\/span><span dir=\"auto\">\u7814\u7a76<\/span><span dir=\"auto\">\u4e0d\u591a\uff0c\u4e14\u7ed9\u836f\u9014\u5f84\u5b58\u5728\u5dee\u5f02\u3002<\/span><span dir=\"auto\">\u76ee\u524d\u5e38\u7528\u7684\u7ed9\u836f\u9014\u5f84\u5305\u62ec\u5c06ADSC\u5206\u5316\u4e3aIPC\uff0c\u7136\u540e\u6ce8\u5c04\u5230\u95e8\u9759\u8109\u3001\u80f8\u817a\u6216\u76ae\u4e0b\u7ec4\u7ec7<\/span><span dir=\"auto\">\u3002\u6216\u8005\uff0c\u53ef\u4ee5\u5c06ADSC\u8bf1\u5bfc\u4e3a\u5177\u6709\u80f0\u5c9b\u7d20\u5206\u6ccc\u529f\u80fd\u7684ADSC\uff0c\u5e76\u4e0e\u672a\u5206\u7ea7\u57f9\u517b\u7684\u9aa8\u9ad3\u7ec6\u80de\u5171\u540c\u79fb\u690d\u5230\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u95e8\u9759\u8109<\/span><span dir=\"auto\">\u00a0\u3002\u901a\u8fc7\u95e8\u9759\u8109\u8f93\u6ce8\u7ed9\u836f\u662f\u56e0\u4e3a\u8fd9\u6837\u53ef\u4ee5<\/span><span dir=\"auto\">\u4f7f<\/span><span dir=\"auto\">\u7ec6\u80de\u7559\u5728\u809d\u810f\u5fae\u5faa\u73af\u4e2d\uff0c\u800c\u809d\u810f\u4f5c\u4e3a\u8010\u53d7\u6027\u5668\u5b98\uff0c\u4e0d\u4f1a\u6392\u65a5\u7ec6\u80de\u690d\u5165\u3002\u4f46\u76ee\u524d\u5c1a\u65e0\u7edf\u4e00\u7684\u7ed9\u836f\u65b9\u6cd5\u53ef\u4ee5\u8fbe\u5230\u66f4\u597d\u7684\u6cbb\u7597\u6548\u679c\u3002\u6b64\u5916\uff0c\u5173\u4e8e\u79fb\u690d\u7684ADSC\u6570\u91cf\uff0c\u76ee\u524d\u5404\u7814\u7a76\u4e5f\u5b58\u5728\u5dee\u5f02\u3002\u4e00\u4e9b\u7814\u7a76\u4f7f\u752810<sup>6<\/sup>\u4e2a\u7ec6\u80de\u7684\u6c34\u5e73<\/span><span dir=\"auto\">(math.) genus<\/span><span dir=\"auto\">(indicates contrast)<\/span><span dir=\"auto\">\u53e6<\/span><span dir=\"auto\">\u4e00\u4e9b<\/span><span dir=\"auto\">\u7814\u7a76\u4f7f\u7528<\/span><span dir=\"auto\">10<\/span><sup><span dir=\"auto\">8<\/span><\/sup><span dir=\"auto\">\u4e2a<\/span><span dir=\"auto\">\u7ec6\u80de\u7684\u6c34\u5e73\uff0c\u5982\u88681<\/span><span dir=\"auto\">\u6240\u793a<\/span><span dir=\"auto\">\u3002\u7136\u800c\uff0c\u8fbe\u5230\u6cbb\u7597\u6548\u679c\u540c\u65f6\u5c3d\u91cf\u964d\u4f4eADSCs\u6f5c\u5728\u98ce\u9669\u6240\u9700\u7684\u5177\u4f53\u7ec6\u80de\u6570\u91cf\u4ecd\u9700\u8981\u8fdb\u4e00\u6b65\u7814\u7a76\u3002<\/span><\/p>\n<div id=\"attachment_20139\" style=\"width: 1260px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20139\" class=\"wp-image-20139 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180844_627.png\" alt=\"\" width=\"1250\" height=\"358\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180844_627.png 1250w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180844_627-300x86.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180844_627-1024x293.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180844_627-768x220.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180844_627-18x5.png 18w\" sizes=\"(max-width: 1250px) 100vw, 1250px\" \/><p id=\"caption-attachment-20139\" class=\"wp-caption-text\">\u88681\uff1a\u4f7f\u7528ADSC\u6cbb\u75971\u578b\u7cd6\u5c3f\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c<\/p><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%971%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E7%9A%84%E4%B8%89%E5%A4%A7%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\"><\/span>\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u75971\u578b\u7cd6\u5c3f\u75c5\u7684\u4e09\u5927\u4f5c\u7528\u673a\u5236<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong>\u5206\u5316\u4e3a\u80f0\u5c9b\u7d20\u751f\u6210\u7ec6\u80de\uff0c\u76f4\u63a5\u66ff\u4ee3\u53d7\u635f\u7684\u03b2\u7ec6\u80de\u529f\u80fd\u3002<\/strong>\u8fd9\u662fADSC\u6cbb\u75971\u578b\u7cd6\u5c3f\u75c5\u6700\u76f4\u63a5\u7684\u6cbb\u7597\u673a\u5236\u3002\u5728\u7279\u5b9a\u56e0\u5b50\u8bf1\u5bfc\u4e0b\uff0cADSCs\u80fd\u591f\u6210\u529f\u5206\u5316\u4e3a\u80f0\u5c9b\u7d20\u751f\u6210\u7ec6\u80de\uff08IPCs\uff09\uff0c\u8fd9\u4e9b\u7ec6\u80de\u5177\u5907\u4ee5\u8461\u8404\u7cd6\u6d53\u5ea6\u4f9d\u8d56\u6027\u65b9\u5f0f\u5206\u6ccc\u80f0\u5c9b\u7d20\u548cC\u80bd\u7684\u80fd\u529b\u3002\u5f53\u5c06\u8fd9\u4e9b\u5206\u5316\u7684IPCs\u79fb\u690d\u5230\u7cd6\u5c3f\u75c5\u52a8\u7269\u4f53\u5185\u540e\uff0c\u80fd\u591f\u663e\u8457\u63d0\u5347\u8840\u6e05\u80f0\u5c9b\u7d20\u6c34\u5e73\uff0c\u5e76\u4f7f\u8840\u7cd6\u6062\u590d\u6b63\u5e38\u3002\u5176\u5206\u5316\u8fc7\u7a0b\u53d7Wnt\u3001PI3K\/Akt\u7b49\u591a\u4e2a\u5173\u952e\u4fe1\u53f7\u901a\u8def\u7684\u7cbe\u5bc6\u8c03\u63a7\u3002<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u901a\u8fc7\u65c1\u5206\u6ccc\u4f5c\u7528\u4fdd\u62a4\u4e0e\u4fee\u590d\u4f53\u5185\u6b8b\u7559\u7684\u80f0\u5c9b\u3002<\/strong>ADSCs\u4e0d\u4ec5\u80fd\u591f\u76f4\u63a5\u5206\u5316\uff0c\u66f4\u80fd\u901a\u8fc7\u5206\u6ccc\u591a\u79cd\u6d3b\u6027\u56e0\u5b50\u6765\u652f\u6301\u548c\u4fdd\u62a4\u60a3\u8005\u4f53\u5185\u5c1a\u5b58\u7684\u529f\u80fd\u53d7\u635f\u7684\u80f0\u5c9b\u3002\u79fb\u690d\u540e\u7684ADSCs\u53ef\u91ca\u653e\u5305\u62ec\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50\uff08VEGF\uff09\u3001\u91d1\u5c5e\u86cb\u767d\u9176\u7ec4\u7ec7\u6291\u5236\u52421\uff08TIMP-1\uff09\u7b49\u5728\u5185\u7684\u591a\u79cd\u7ec6\u80de\u56e0\u5b50\uff0c\u8fd9\u4e9b\u56e0\u5b50\u80fd\u6709\u6548\u9632\u6b62\u03b2\u7ec6\u80de\u51cb\u4ea1\u5e76\u4fc3\u8fdb\u5176\u589e\u6b96\u3002\u540c\u65f6\uff0cADSCs\u8fd8\u80fd\u8c03\u8282\u81ea\u8eab\u514d\u75ab\uff0c\u901a\u8fc7\u964d\u4f4e\u4fc3\u708e\u7684Th1\u514d\u75ab\u5e94\u7b54\u548c\u8bf1\u5bfc\u8c03\u8282\u6027T\u7ec6\u80de\uff08Tregs\uff09\u589e\u6b96\uff0c\u6765\u6539\u5584\u653b\u51fb\u80f0\u5c9b\u7684\u81ea\u8eab\u514d\u75ab\u73af\u5883\uff0c\u4ece\u800c\u4fdd\u62a4\u6b8b\u7559\u7684\u80f0\u5c9b\u529f\u80fd\u3002<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u589e\u5f3a\u79fb\u690d\u80f0\u5c9b\u7684\u6d3b\u529b\u4e0e\u529f\u80fd\uff0c\u63d0\u9ad8\u79fb\u690d\u6210\u529f\u7387\u3002<\/strong>\u5728\u80f0\u5c9b\u79fb\u690d\u6cbb\u7597\u4e2d\uff0cADSCs\u626e\u6f14\u7740\u91cd\u8981\u7684\u201c\u8f85\u52a9\u201d\u89d2\u8272\u3002\u65e0\u8bba\u662f\u4f53\u5916\u4e0e\u80f0\u5c9b\u5171\u57f9\u517b\u8fdb\u884c\u9884\u5904\u7406\uff0c\u8fd8\u662f\u76f4\u63a5\u5c06ADSCs\u4e0e\u80f0\u5c9b\u5171\u540c\u79fb\u690d\uff0cADSCs\u90fd\u80fd\u901a\u8fc7\u5206\u6ccc\u5927\u91cf\u8840\u7ba1\u751f\u6210\u56e0\u5b50\uff08\u5982VEGF\uff09\u4fc3\u8fdb\u79fb\u690d\u80f0\u5c9b\u5185\u7684\u65b0\u751f\u8840\u7ba1\u5f62\u6210\uff0c\u4e3a\u5176\u63d0\u4f9b\u5145\u8db3\u7684\u8425\u517b\u548c\u6c27\u6c14\u3002\u6b64\u5916\uff0cADSCs\u8fd8\u80fd\u663e\u8457\u6291\u5236\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u4ea7\u751f\u5e76\u51cf\u5c11\u708e\u75c7\u7ec6\u80de\u6d78\u6da6\uff0c\u4e3a\u79fb\u690d\u7684\u80f0\u5c9b\u521b\u9020\u4e00\u4e2a\u514d\u75ab\u8c41\u514d\u3001\u4f4e\u708e\u75c7\u7684\u6709\u5229\u5fae\u73af\u5883\uff0c\u4ece\u800c\u663e\u8457\u5ef6\u957f\u5176\u5b58\u6d3b\u65f6\u95f4\u5e76\u6539\u5584\u5176\u529f\u80fd\u3002<\/p>\n<h2 id=\"Sec9\" class=\"c-article-section__title js-section-title js-c-reading-companion-sections-item\"><span class=\"ez-toc-section\" id=\"ADSCs%E5%9C%A82%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E4%B8%AD%E7%9A%84%E5%BA%94%E7%94%A8\"><\/span><span dir=\"auto\">ADSCs\u57282\u578b\u7cd6\u5c3f\u75c5\u4e2d\u7684\u5e94\u7528<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<div id=\"Sec9-content\" class=\"c-article-section__content\">\n<p><span dir=\"auto\">2\u578b\u7cd6\u5c3f\u75c5\u7684\u7279\u5f81\u662f\u80f0\u5c9b\u7d20\u53cd\u5e94\u7ec4\u7ec7\u51fa\u73b0\u80f0\u5c9b\u7d20\u62b5\u6297\uff0c\u80f0\u817a\u03b2\u7ec6\u80de\u80f0\u5c9b\u7d20\u5206\u6ccc\u53d7\u635f\u3002\u8fd9\u7c7b\u7cd6\u5c3f\u75c5\u5360\u6240\u6709\u7cd6\u5c3f\u75c5\u75c5\u4f8b\u768485%-95%<\/span><span dir=\"auto\">\u3002\u6b64\u5916\uff0c\u8425\u517b\u8fc7\u5269\u53ef\u5bfc\u81f4\u8102\u80aa\u7ec4\u7ec7\u708e\u75c7\uff0c\u5f71\u54cd<\/span><span dir=\"auto\">\u591a\u4e2a\u7ec4\u7ec7\uff0c\u5e76\u964d\u4f4e\u80f0\u5c9b\u7d20\u654f\u611f\u6027\u548c\u03b2\u7ec6\u80de\u529f\u80fd<\/span><a id=\"ref-link-section-d128938565e2509\" title=\"\u708e\u75c7\u7684\u751f\u7269\u80fd\u91cf\u5b66\uff1a\u5bf9\u80a5\u80d6\u548c2\u578b\u7cd6\u5c3f\u75c5\u7684\u6d1e\u5bdf\u3002\u300a\u6b27\u6d32\u4e34\u5e8a\u8425\u517b\u5b66\u6742\u5fd7\u300b\u30022017\uff1b71(7):904-12\u3002\" href=\"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-023-03620-0#ref-CR86\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e 86\" rel=\"nofollow noopener\" target=\"_blank\"><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">The<\/span><\/span><\/span><a id=\"ref-link-section-d128938565e2512\" title=\"Velloso LA\uff0cEizirik DL\uff0cCnop M. 2\u578b\u7cd6\u5c3f\u75c5-\u4e00\u79cd\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff1fNat Rev Endocrinol\u30022013\uff1b9(12)\uff1a750-5\u3002\" href=\"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-023-03620-0#ref-CR87\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e 87\" rel=\"nofollow noopener\" target=\"_blank\"><\/a><\/p>\n<p><span dir=\"auto\">\u76ee\u524d\uff0c\u5229\u7528\u8102\u80aa\u5e72\u7ec6\u80de\uff08ADSC\uff09\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8f83\u5c11\uff0c\u5927\u591a\u6570\u5e94\u7528\u4ecd\u5728\u52a8\u7269\u5b9e\u9a8c\u4e2d\u8fdb\u884c\u9a8c\u8bc1\u3002\u52a8\u7269\u5b9e\u9a8c\u8868\u660e\uff0c\u901a\u8fc7\u5c0f\u9f20\u5c3e\u9759\u8109\u3001\u8179\u819c\u548c\u80be\u5305\u819c\u6ce8\u5c04ADSC\uff0c\u53ef\u901a\u8fc7\u6062\u590d\u80f0\u817a\u03b2\u7ec6\u80de\u3001\u51cf\u8f7b\u708e\u75c7\u3001\u589e\u52a0\u80f0\u5c9b\u7d20\u654f\u611f\u6027\u7b49\u65b9\u5f0f\u6539\u5584\u9ad8\u8840\u7cd6<a id=\"ref-link-section-d128938565e2524_1\" title=\"Chandra V, Swetha G, Phadnis S, Nair PD, Bhonde RR. \u4ece\u5c0f\u9f20\u8102\u80aa\u7ec4\u7ec7\u6765\u6e90\u7684\u5e72\u7ec6\u80de\u4e2d\u751f\u6210\u8868\u8fbe\u80f0\u817a\u6fc0\u7d20\u7684\u80f0\u5c9b\u6837\u7ec6\u80de\u805a\u96c6\u4f53\u3002\u5e72\u7ec6\u80de\u30022009;27(8):1941\u201353\u3002\" href=\"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-023-03620-0#ref-CR91\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" rel=\"nofollow noopener\" target=\"_blank\"><\/a>\u3002\u90e8\u5206\u673a\u5236\u7684<\/span><span dir=\"auto\">\u63a2\u7d22\u4e3aADSC\u7684\u4e34\u5e8a\u5e94\u7528\u63d0\u4f9b\u4e86\u65b0\u7684\u65b9\u5411<\/span><span dir=\"auto\">\u3002\u00a0\u8be6\u89c1\u88682\u3002<\/span><\/p>\n<div id=\"attachment_20136\" style=\"width: 1264px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20136\" class=\"wp-image-20136 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180535_293.png\" alt=\"\u88682\uff1aADSCs\u5e94\u7528\u4e8eT2DM\u7684\u52a8\u7269\u5b9e\u9a8c\" width=\"1254\" height=\"665\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180535_293.png 1254w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180535_293-300x159.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180535_293-1024x543.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180535_293-768x407.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-28_180535_293-18x10.png 18w\" sizes=\"(max-width: 1254px) 100vw, 1254px\" \/><p id=\"caption-attachment-20136\" class=\"wp-caption-text\">\u88682\uff1aADSCs\u5e94\u7528\u4e8eT2DM\u7684\u52a8\u7269\u5b9e\u9a8c<\/p><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%972%E5%9E%8B%E7%B3%96%E5%B0%BF%E7%97%85%E7%9A%84%E4%B8%89%E5%A4%A7%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\"><\/span>\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u7684\u4e09\u5927\u4f5c\u7528\u673a\u5236<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong>\u6539\u5584\u80f0\u5c9b\u7d20\u62b5\u6297\u3002<\/strong>\u00a0\u8fd9\u662fADSCs\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u7684\u5173\u952e\u673a\u5236\u3002\u5728\u7cd6\u5c3f\u75c5\u6a21\u578b\u4e2d\uff0c\u79fb\u690d\u7684ADSCs\u80fd\u591f\u4f5c\u7528\u4e8e\u9aa8\u9abc\u808c\u3001\u809d\u810f\u548c\u8102\u80aa\u7b49\u80f0\u5c9b\u7d20\u654f\u611f\u7ec4\u7ec7\uff0c\u6062\u590d\u5176\u7ec6\u80de\u819c\u4e0a\u7684\u8461\u8404\u7cd6\u8f6c\u8fd0\u86cb\u767d4\u548c\u80f0\u5c9b\u7d20\u53d7\u4f53\u6570\u91cf\uff0c\u5e76\u589e\u5f3a\u80f0\u5c9b\u7d20\u4fe1\u53f7\u901a\u8def\u4e2d\u80f0\u5c9b\u7d20\u53d7\u4f53\u5e95\u7269\u7684\u78f7\u9178\u5316\uff0c\u4ece\u800c\u76f4\u63a5\u6539\u5584\u7ec6\u80de\u5bf9\u80f0\u5c9b\u7d20\u7684\u54cd\u5e94\u3002\u66f4\u91cd\u8981\u7684\u662f\uff0cADSCs\u80fd\u663e\u8457\u964d\u4f4eTNF-\u03b1\u3001IL-6\u7b49\u5173\u952e\u4fc3\u708e\u56e0\u5b50\u7684\u6c34\u5e73\uff0c\u901a\u8fc7\u6291\u5236\u80a5\u80d6\u76f8\u5173\u7684\u5168\u8eab\u6027\u6162\u6027\u708e\u75c7\u6765\u89e3\u9664\u5176\u5bf9\u80f0\u5c9b\u7d20\u4fe1\u53f7\u901a\u8def\u7684\u963b\u788d\uff0c\u4ece\u6839\u672c\u4e0a\u7f13\u89e3\u80f0\u5c9b\u7d20\u62b5\u6297\u72b6\u6001\u3002<\/p>\n<p 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class=\"ds-markdown-paragraph\">\u603b\u4f53\u800c\u8a00\uff0cADSCs\u901a\u8fc7\u4fee\u590d\u5fae\u8840\u7ba1\u3001\u4fdd\u62a4\u5185\u76ae\u7ec6\u80de\u548c\u6297\u708e\u7b49\u591a\u91cd\u673a\u5236\uff0c\u4e3a\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u75c5\u53d8\u63d0\u4f9b\u4e86\u6709\u524d\u666f\u7684\u6cbb\u7597\u7b56\u7565\u3002\u5c3d\u7ba1\u52a8\u7269\u5b9e\u9a8c\u6210\u679c\u663e\u8457\uff0c\u663e\u793a\u5176\u80fd\u6709\u6548\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\uff0c\u4f46\u76ee\u524d\u7814\u7a76\u4ecd\u5904\u4e8e\u4e34\u5e8a\u524d\u9636\u6bb5\uff0c\u6700\u4f73\u79fb\u690d\u65b9\u6cd5\u3001\u7ec6\u80de\u7cbe\u51c6\u5b9a\u4f4d\u53ca\u5177\u4f53\u4f5c\u7528\u673a\u5236\u5c1a\u4e0d\u5b8c\u5168\u660e\u786e\uff0c\u8ddd\u79bb\u771f\u6b63\u4e34\u5e8a\u5e94\u7528\u5c1a\u6709\u8f83\u957f\u8ddd\u79bb\uff0c\u9700\u8981\u8fdb\u4e00\u6b65\u7684\u6df1\u5165\u7814\u7a76\u6765\u63a8\u52a8\u5176\u5411\u4e34\u5e8a\u6cbb\u7597\u65b9\u6848\u7684\u8f6c\u5316\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B3%96%E5%B0%BF%E7%97%85%E8%82%BE%E7%97%85%E7%9A%84%E5%BA%94%E7%94%A8\"><\/span>\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u80be\u75c5\u7684\u5e94\u7528<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\">\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5728\u6cbb\u7597\u7cd6\u5c3f\u75c5\u80be\u75c5\u4e2d\u7684\u5e94\u7528\uff0c\u4e3b\u8981\u4f53\u73b0\u5728\u5176\u5206\u6ccc\u7684\u5916\u6ccc\u4f53\u6240\u4ecb\u5bfc\u7684\u591a\u91cd\u4fdd\u62a4\u673a\u5236\u3002<\/p>\n<p class=\"ds-markdown-paragraph\">\u7cd6\u5c3f\u75c5\u80be\u75c5\u7684\u4e3b\u8981\u7279\u5f81\u662f\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\u4e0b\u964d\u3001\u86cb\u767d\u5c3f\u4ee5\u53ca\u8fdb\u884c\u6027\u7684\u80be\u7ea4\u7ef4\u5316\uff0c\u5176\u75c5\u7406\u8fc7\u7a0b\u6d89\u53ca\u9ad8\u8840\u7cd6\u5f15\u53d1\u7684\u8db3\u7ec6\u80de\u635f\u4f24\u3001\u6c27\u5316\u5e94\u6fc0\u3001\u708e\u75c7\u53cd\u5e94\u53caECM\u8fc7\u5ea6\u79ef\u805a\u3002\u800cADSCs\u6765\u6e90\u7684\u5916\u6ccc\u4f53\u4f5c\u4e3a\u4e00\u79cd\u7eb3\u7c73\u7ea7\u56ca\u6ce1\uff0c\u80fd\u591f\u5c06\u751f\u7269\u6d3b\u6027\u7269\u8d28\u5982\u5fae\u5c0fRNA\u9012\u9001\u81f3\u80be\u810f\u9776\u7ec6\u80de\uff0c\u4e3a\u5e72\u9884\u8fd9\u4e00\u590d\u6742\u8fc7\u7a0b\u63d0\u4f9b\u4e86\u65b0\u7b56\u7565\u3002<\/p>\n<p class=\"ds-markdown-paragraph\">ADSCs\u6cbb\u7597\u7cd6\u5c3f\u75c5\u80be\u75c5\u7684\u6838\u5fc3\u673a\u5236\u5728\u4e8e\u5176\u5916\u6ccc\u4f53\u5bf9\u8db3\u7ec6\u80de\u7684\u5173\u952e\u4fdd\u62a4\u4f5c\u7528\u3002\u7814\u7a76\u8bc1\u5b9e\uff0cADSCs-Exos\u53ef\u901a\u8fc7\u643a\u5e26\u7279\u5b9a\u7684miRNA\uff0c\u7cbe\u51c6\u8c03\u63a7\u591a\u4e2a\u4fe1\u53f7\u901a\u8def\uff0c\u4ece\u800c\u51cf\u8f7b\u80be\u635f\u4f24\u3002\u4f8b\u5982\uff0c\u5916\u6ccc\u4f53\u4e2d\u7684miR-26a-5p\u53ef\u901a\u8fc7\u9776\u5411TLR4\/NF-\u03baB\u901a\u8def\uff0c\u4e0b\u8c03VEGFA\u8868\u8fbe\u5e76\u6291\u5236\u6c27\u5316\u5e94\u6fc0\uff0c\u9632\u6b62\u9ad8\u7cd6\u8bf1\u5bfc\u7684\u8db3\u7ec6\u80de\u51cb\u4ea1\uff1bmiR-486\u5219\u901a\u8fc7\u6291\u5236Smad1\/mTOR\u901a\u8def\u6765\u4fc3\u8fdb\u81ea\u566c\uff0c\u51cf\u5c11\u8db3\u7ec6\u80de\u51cb\u4ea1\uff1b\u800cmiR-215-5p\u80fd\u901a\u8fc7\u6291\u5236ZEB2\u8868\u8fbe\uff0c\u5ef6\u7f13\u4e0a\u76ae-\u95f4\u8d28\u8f6c\u5316\u8fdb\u7a0b\u3002\u8fd9\u4e9b\u673a\u5236\u5171\u540c\u4f5c\u7528\uff0c\u6709\u6548\u7a33\u5b9a\u4e86\u80be\u5c0f\u7403\u6ee4\u8fc7\u5c4f\u969c\u7684\u6838\u5fc3\u7ed3\u6784\u3002<\/p>\n<p class=\"ds-markdown-paragraph\">\u7efc\u4e0a\u6240\u8ff0\uff0c\u57fa\u4e8e\u5916\u6ccc\u4f53\u7684ADSCs\u7597\u6cd5\u901a\u8fc7\u9012\u9001\u591a\u79cd\u4fdd\u62a4\u6027miRNA\uff0c\u5728\u591a\u73af\u8282\u4e0a\u5ef6\u7f13\u4e86\u7cd6\u5c3f\u75c5\u80be\u75c5\u7684\u8fdb\u5c55\uff0c\u5c55\u73b0\u51fa\u5de8\u5927\u7684\u6cbb\u7597\u6f5c\u529b\u3002\u7136\u800c\uff0c\u8be5\u6280\u672f\u8d70\u5411\u4e34\u5e8a\u4ecd\u9762\u4e34\u6311\u6218\uff0c\u5305\u62ec\u9700\u8981\u4f18\u5316\u5916\u6ccc\u4f53\u7684\u5236\u5907\u5de5\u827a\u3001\u660e\u786e\u5176\u5185\u7684\u5173\u952e\u6d3b\u6027\u5206\u5b50\u3001\u5e76\u5f00\u53d1\u80fd\u5c06\u5916\u6ccc\u4f53\u7cbe\u51c6\u9012\u9001\u81f3\u80be\u810f\u75c5\u7076\u7684\u65b9\u6cd5\u3002\u89e3\u51b3\u8fd9\u4e9b\u95ee\u9898\u5c06\u662f\u63a8\u52a8\u5176\u4ece\u57fa\u7840\u7814\u7a76\u5411\u4e34\u5e8a\u5e94\u7528\u8f6c\u5316\u7684\u5173\u952e\u3002<\/p>\n<p><span dir=\"auto\">\u8fd1\u5e74\u6765\u7684\u7814\u7a76\u8868\u660e\uff0c\u809d\u810f\u6539\u53d8\u662f\u7cd6\u5c3f\u75c5\u7684\u53e6\u4e00\u9879\u5e76\u53d1\u75c7<\/span><span dir=\"auto\">\u3002\u7cd6\u5c3f\u75c5\u5f15\u8d77\u7684\u9ad8\u8840\u7cd6\u4f1a\u589e\u52a0\u809d\u635f\u4f24\u548c\u809d\u7ea4\u7ef4\u5316\u7684\u98ce\u9669<\/span><span dir=\"auto\">\uff0c\u4e25\u91cd\u5f71\u54cd\u60a3\u8005\u7684\u5065\u5eb7\u548c\u751f\u6d3b\u8d28\u91cf\u3002\u7cd6\u5c3f\u75c5\u4e0e\u809d\u810f\u75be\u75c5\u5bc6\u5207\u76f8\u5173<\/span><span dir=\"auto\">\uff0c\u4f46\u7cd6\u5c3f\u75c5\u809d\u810f\u6539\u53d8\u7684\u75c5\u7406\u751f\u7406\u57fa\u7840\u548c\u8fdb\u5c55\u5c1a\u4e0d\u5b8c\u5168\u6e05\u695a\uff0c\u7f3a\u4e4f\u6709\u6548\u7684\u65e9\u671f\u5e72\u9884\u63aa\u65bd\u3002<\/span><span dir=\"auto\">\u4e00\u4e9b\u7814\u7a76\u5c1d\u8bd5\u5c06ADSC\u79fb\u690d\u5230\u52a8\u7269\u4f53\u5185\uff0c\u4ee5\u51cf\u8f7b\u7cd6\u5c3f\u75c5\u5f15\u8d77\u7684\u809d\u635f\u4f24\u548c\u7ea4\u7ef4\u5316\uff0c\u5e76\u53d6\u5f97\u4e86\u4e00\u5b9a\u7684\u79ef\u6781\u6210\u679c\u3002<\/span><a id=\"ref-link-section-d128938565e4843\" title=\"\u5ed6\u5a1c\uff0c\u90d1\u52c7\uff0c\u8c22\u534e\uff0c\u8d75\u658c\uff0c\u66fe\u52c7\uff0c\u5218\u6653\u73b2\uff0c\u5218\u5efa\u519b\u3002\u8102\u80aa\u7ec4\u7ec7\u6765\u6e90\u7684\u5e72\u7ec6\u80de\u6539\u55842\u578b\u7cd6\u5c3f\u75c5\u5927\u9f20\u7684\u9ad8\u8840\u7cd6\u3001\u80f0\u5c9b\u7d20\u62b5\u6297\u548c\u809d\u7ea4\u7ef4\u5316\u3002\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u30022017\uff1b8(1):286\u3002\" href=\"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-023-03620-0#ref-CR168\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003 168\" rel=\"nofollow noopener\" target=\"_blank\"><\/a><span dir=\"auto\">\u8fd9\u4e3a\u8fdb\u4e00\u6b65\u7814\u7a76\u548c\u5f00\u53d1ADSC\u7528\u4e8e\u6cbb\u7597\u7cd6\u5c3f\u75c5\u76f8\u5173\u809d\u75c5\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u7406\u8bba\u548c\u5b9e\u9a8c\u57fa\u7840\u3002\u4f46\u5c1a\u672a\u5f00\u5c55\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5bf9ADSC\u7684\u6cbb\u7597\u673a\u5236\u548c\u9014\u5f84\u7684\u9610\u8ff0\u4e5f\u4e0d\u591f\u8be6\u7ec6\uff0c\u9700\u8981\u8fdb\u4e00\u6b65\u7684\u7814\u7a76\u6765\u9610\u660e\u3002<\/span><\/p>\n<p><span dir=\"auto\">ADSCs\u5728\u7cd6\u5c3f\u75c5\u5e76\u53d1\u75c7\u4e2d\u5e94\u7528\u7684\u6f5c\u5728\u673a\u5236\u603b\u7ed3\u4e8e\u56fe2<\/span><span dir=\"auto\">\u4e2d\u3002<\/span><\/p>\n<div id=\"attachment_20138\" style=\"width: 1780px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20138\" class=\"wp-image-20138 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/\u5fae\u4fe1\u56fe\u7247_2025-10-28_180131_029.png\" alt=\"\u56fe2\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08 ADSCs\uff09\u5728\u7cd6\u5c3f\u75c5\u5e76\u53d1\u75c7\u4e2d\u7684\u5e94\u7528\u53ca\u673a\u5236\u3002\" width=\"1770\" height=\"1249\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/\u5fae\u4fe1\u56fe\u7247_2025-10-28_180131_029.png 1770w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/\u5fae\u4fe1\u56fe\u7247_2025-10-28_180131_029-300x212.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/\u5fae\u4fe1\u56fe\u7247_2025-10-28_180131_029-1024x723.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/\u5fae\u4fe1\u56fe\u7247_2025-10-28_180131_029-768x542.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/\u5fae\u4fe1\u56fe\u7247_2025-10-28_180131_029-1536x1084.png 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/\u5fae\u4fe1\u56fe\u7247_2025-10-28_180131_029-18x12.png 18w\" sizes=\"(max-width: 1770px) 100vw, 1770px\" \/><p id=\"caption-attachment-20138\" class=\"wp-caption-text\">\u56fe2\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08 ADSCs\uff09\u5728\u7cd6\u5c3f\u75c5\u5e76\u53d1\u75c7\u4e2d\u7684\u5e94\u7528\u53ca\u673a\u5236\u3002<\/p><\/div>\n<h2 id=\"Sec19\" class=\"c-article-section__title js-section-title js-c-reading-companion-sections-item\"><span class=\"ez-toc-section\" id=\"%E7%BB%93%E8%AE%BA\"><\/span><span dir=\"auto\">reach a verdict<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<div id=\"Sec19-content\" class=\"c-article-section__content\">\n<p><span dir=\"auto\">\u7efc\u4e0a\u6240\u8ff0\uff0c\u8d8a\u6765\u8d8a\u591a\u7684\u7814\u7a76\u8868\u660e\uff0cADSCs\u6216\u53ef\u6210\u4e3a\u6cbb\u7597\u7cd6\u5c3f\u75c5\u7684\u65b0\u9014\u5f84\u3002ADSCs\u6cbb\u7597\u6709\u671b\u6539\u5584\u52a8\u7269\u548c\u4eba\u7c7b\u7684\u9ad8\u8840\u7cd6\u6c34\u5e73\uff0c\u5e76\u7f13\u89e3\u76f8\u5173\u5e76\u53d1\u75c7\u7684\u75c7\u72b6\u3002\u7136\u800c\uff0c\u8981\u5c06ADSCs \u8f6c\u5316\u4e3a\u5b9e\u9645\u7684\u4e34\u5e8a\u5e94\u7528\uff0c\u4ecd\u6709\u8bb8\u591a\u5de5\u4f5c\u8981\u505a\u3002\u9700\u8981\u8fdb\u4e00\u6b65\u7684\u7814\u7a76\u548c\u4e34\u5e8a\u89c2\u5bdf\uff0c\u4ee5\u8bc4\u4f30ADSCs\u6cbb\u7597\u7684\u957f\u671f\u6548\u679c\uff0c\u5e76\u6700\u5927\u9650\u5ea6\u5730\u964d\u4f4e\u5176\u4f7f\u7528\u7684\u6f5c\u5728\u98ce\u9669\uff0c\u4ece\u800c\u5728\u672a\u6765\u7684\u4e34\u5e8a\u5e94\u7528\u4e2d\u53d6\u5f97\u66f4\u53ef\u9760\u3001\u66f4\u6709\u6548\u7684\u7597\u6548\u3002<\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e3b\u8981\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/span><br \/>\n<span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[1]:Yan, D., Song, Y., Zhang, B. <\/span><\/span><i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">et al.<\/span><\/span><\/i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0Progress and application of adipose-derived stem cells in the treatment of diabetes and its concomplications.\u00a0 <\/span><\/span><i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Stem Cell Res Ther <\/span><\/span><\/i>\u00a0<b><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">15<\/span><\/span><\/b><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> , 3 (2024). https:\/\/doi.org\/10.1186\/s13287-023-03620-0<\/span><\/span><\/p>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u7cd6\u5c3f\u75c5\uff08DM\uff09\u662f\u4e00\u79cd\u4e25\u91cd\u7684\u6162\u6027\u4ee3\u8c22\u6027\u75be\u75c5\uff0c\u5e38\u5f15\u53d1\u5fc3\u8840\u7ba1\u75be\u75c5\u3001\u89c6\u7f51\u819c\u75c5\u53d8\u3001\u795e\u7ecf\u75c5\u53d8\u548c\u80be\u810f\u75be\u75c5\u7b49\u4e25\u91cd\u5e76\u53d1\u75c7\u3002\u60a3\u8005\u786e [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[76],"tags":[188,212,204,178],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20130"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/comments?post=20130"}],"version-history":[{"count":1,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20130\/revisions"}],"predecessor-version":[{"id":20146,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20130\/revisions\/20146"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media?parent=20130"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/categories?post=20130"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/tags?post=20130"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}