{"id":20191,"date":"2025-10-29T19:28:45","date_gmt":"2025-10-29T11:28:45","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=20191"},"modified":"2025-10-29T19:28:45","modified_gmt":"2025-10-29T11:28:45","slug":"%e9%97%b4%e5%85%85%e8%b4%a8%e5%b9%b2%e7%bb%86%e8%83%9e%e6%b2%bb%e7%96%97%e7%b3%96%e5%b0%bf%e7%97%85","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html","title":{"rendered":"\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u80fd\u5426\u8c03\u63a7\u8840\u7cd6\uff1f7\u9879\u7814\u7a76\u3001413\u540d\u60a3\u8005\u6570\u636e\u544a\u8bc9\u4f60\u7b54\u6848"},"content":{"rendered":"<p class=\"ds-markdown-paragraph\"><a href=\"https:\/\/www.hjtdsm.cn\/en\/research\/es\/diabetes\/20123.html\/\" target=\"_blank\" rel=\"noopener\">diabetes<\/a>\u662f\u4e00\u79cd\u4e25\u91cd\u7684\u6162\u6027\u4ee3\u8c22\u6027\u75be\u75c5\uff0c\u4e3b\u8981\u5206\u4e3a\u56e0\u81ea\u8eab\u514d\u75ab\u5bfc\u81f4\u80f0\u5c9b\u7d20\u7edd\u5bf9\u7f3a\u4e4f\u7684<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20179.html\/\" target=\"_blank\" rel=\"noopener\">1\u578b\u7cd6\u5c3f\u75c5<\/a>\u548c\u56e0\u80f0\u5c9b\u7d20\u62b5\u6297\u4f34\u5206\u6ccc\u4e0d\u8db3\u76842\u578b\u7cd6\u5c3f\u75c5\u3002\u5168\u7403\u6210\u4eba\u7cd6\u5c3f\u75c5\u60a3\u8005\u5df2\u8fbe4.63\u4ebf\uff0c\u4e2d\u56fd\u6210\u4eba\u60a3\u75c5\u7387\u9ad8\u8fbe10.9%\uff0c\u5176\u6d41\u884c\u4e0e\u4e0d\u5065\u5eb7\u996e\u98df\u3001\u7f3a\u4e4f\u8fd0\u52a8\u3001\u8001\u9f84\u5316\u53ca\u80a5\u80d6\u7b49\u56e0\u7d20\u5bc6\u5207\u76f8\u5173\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20206 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-2195158078-612x612-1.jpg\" alt=\"\u91cd\u78c5\uff1a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u80fd\u5426\u8c03\u63a7\u8840\u7cd6\uff1f7\u9879\u7814\u7a76\u3001413\u540d\u60a3\u8005\u6570\u636e\u544a\u8bc9\u4f60\u7b54\u6848\" width=\"612\" height=\"408\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-2195158078-612x612-1.jpg 612w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-2195158078-612x612-1-300x200.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/istockphoto-2195158078-612x612-1-18x12.jpg 18w\" sizes=\"(max-width: 612px) 100vw, 612px\" \/><\/p>\n<p class=\"ds-markdown-paragraph\">\u5f53\u524d\u7cd6\u5c3f\u75c5\u6cbb\u7597\u4e3b\u8981\u4f9d\u8d56\u53e3\u670d\u964d\u7cd6\u836f\u548c\u80f0\u5c9b\u7d20\u6ce8\u5c04\uff0c\u4f46\u8fd9\u4e9b\u65b9\u6cd5\u5e38\u96be\u4ee5\u7cbe\u51c6\u63a7\u5236\u8840\u7cd6\uff0c\u6613\u5f15\u53d1\u4f4e\u8840\u7cd6\uff0c\u4e14\u60a3\u8005\u4f9d\u4ece\u6027\u5dee\u3002\u4f20\u7edf\u624b\u6bb5\u5728\u963b\u6b62\u75be\u75c5\u8fdb\u5c55\u65b9\u9762\u6548\u679c\u6709\u9650\uff0c\u4e34\u5e8a\u4e0a\u8feb\u5207\u9700\u8981\u65b0\u7684\u6cbb\u7597\u7b56\u7565\u3002\u5728\u6b64\u80cc\u666f\u4e0b\uff0c<strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5<\/strong>\u56e0\u5176\u591a\u6548\u6027\u548c\u4f4e\u514d\u75ab\u539f\u6027\u6210\u4e3a\u65b0\u5174\u65b9\u5411\uff0c\u4f46\u73b0\u6709\u4e34\u5e8a\u7814\u7a76\u7ed3\u8bba\u4e0d\u4e00\uff0c\u4f7f\u5f97\u5176\u7597\u6548\u4e0e\u5b89\u5168\u6027\u4e9f\u9700\u7cfb\u7edf\u8bc4\u4f30\u3002<\/p>\n<p class=\"ds-markdown-paragraph\">\u4e3a\u63d0\u4f9b\u53ef\u9760\u8bc1\u636e\uff0c\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b49\u673a\u6784\u4e8e2021\u5e74\u5728<a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0247662\" target=\"_blank\" rel=\"noopener nofollow\">\u300aPlos One\u300b<\/a>\u4e0a\u53d1\u8868\u4e86\u4e00\u9879\u7cfb\u7edf\u8bc4\u4ef7\u4e0e\u835f\u8403\u5206\u6790\uff0c\u65e8\u5728\u7efc\u5408\u73b0\u6709\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u7684\u6570\u636e\uff0c\u660e\u786e\u56de\u7b54\u8fd9\u4e00\u95ee\u9898\uff1a<\/p>\n<div id=\"attachment_20205\" style=\"width: 1019px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20205\" class=\"wp-image-20205 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/wechat_2025-10-29_192227_553.png\" 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class=\"wp-caption-text\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u60a3\u8005\u8840\u7cd6\u63a7\u5236\u7684\u4e34\u5e8a\u7597\u6548\u53ca\u5b89\u5168\u6027\uff1a\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u6570\u636e\u7684\u7cfb\u7edf\u8bc4\u4ef7\u548c\u835f\u8403\u5206\u6790<\/p><\/div>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" 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href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#%E9%87%8D%E7%A3%85%EF%BC%9A%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B3%96%E5%B0%BF%E7%97%85%E8%83%BD%E5%90%A6%E8%B0%83%E6%8E%A7%E8%A1%80%E7%B3%96%EF%BC%9F7%E9%A1%B9%E7%A0%94%E7%A9%B6%E3%80%81413%E5%90%8D%E6%82%A3%E8%80%85%E6%95%B0%E6%8D%AE%E5%91%8A%E8%AF%89%E4%BD%A0%E7%AD%94%E6%A1%88\" >\u91cd\u78c5\uff1a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u80fd\u5426\u8c03\u63a7\u8840\u7cd6\uff1f7\u9879\u7814\u7a76\u3001413\u540d\u60a3\u8005\u6570\u636e\u544a\u8bc9\u4f60\u7b54\u6848<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#%E7%A0%94%E7%A9%B6%E8%AE%BE%E8%AE%A1%E4%B8%8E%E6%96%B9%E6%B3%95\" >\u7814\u7a76\u8bbe\u8ba1\u4e0e\u65b9\u6cd5<\/a><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B3%96%E5%B0%BF%E7%97%85%E6%82%A3%E8%80%85%E8%A1%80%E7%B3%96%E6%8E%A7%E5%88%B6%E7%9A%84%E4%B8%B4%E5%BA%8A%E7%96%97%E6%95%88%E5%8F%8A%E5%AE%89%E5%85%A8%E6%80%A7%E7%9A%84%E7%BB%93%E6%9E%9C\" >\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u60a3\u8005\u8840\u7cd6\u63a7\u5236\u7684\u4e34\u5e8a\u7597\u6548\u53ca\u5b89\u5168\u6027\u7684\u7ed3\u679c<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#%E8%AF%95%E9%AA%8C%E9%80%89%E6%8B%A9%E5%92%8C%E5%9F%BA%E6%9C%AC%E7%89%B9%E5%BE%81\" >\u8bd5\u9a8c\u9009\u62e9\u548c\u57fa\u672c\u7279\u5f81<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#%E7%A0%94%E7%A9%B6%E7%89%B9%E5%BE%81\" >\u7814\u7a76\u7279\u5f81<\/a><\/li><\/ul><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97413%E5%90%8D%E7%B3%96%E5%B0%BF%E7%97%85%E6%82%A3%E8%80%85%E8%A1%80%E7%B3%96%E6%8E%A7%E5%88%B6%E7%9A%84%E6%95%88%E6%9E%9C\" >\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597413\u540d\u7cd6\u5c3f\u75c5\u60a3\u8005\u8840\u7cd6\u63a7\u5236\u7684\u6548\u679c<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#1_FPG%EF%BC%88%E7%A9%BA%E8%85%B9%E8%A1%80%E7%B3%96%EF%BC%89\" >1. FPG\uff08\u7a7a\u8179\u8840\u7cd6\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#2_HbA1c%EF%BC%88%E7%B3%96%E5%8C%96%E8%A1%80%E7%BA%A2%E8%9B%8B%E7%99%BD%EF%BC%89\" >2. HbA1c\uff08\u7cd6\u5316\u8840\u7ea2\u86cb\u767d\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#3_%E7%A9%BA%E8%85%B9C%E8%82%BD\" >3. \u7a7a\u8179C\u80bd<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#%E7%BB%93%E8%AE%BA\" >reach a verdict<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#%E5%AE%89%E5%85%A8%E7%BB%93%E6%9E%9C\" >\u5b89\u5168\u7ed3\u679c<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#%E8%AE%A8%E8%AE%BA\" >\u8ba8\u8bba<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20191.html\/#%E7%BB%93%E8%AE%BA-2\" >reach a verdict<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2 class=\"ds-markdown-paragraph\"><span class=\"ez-toc-section\" id=\"%E9%87%8D%E7%A3%85%EF%BC%9A%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B3%96%E5%B0%BF%E7%97%85%E8%83%BD%E5%90%A6%E8%B0%83%E6%8E%A7%E8%A1%80%E7%B3%96%EF%BC%9F7%E9%A1%B9%E7%A0%94%E7%A9%B6%E3%80%81413%E5%90%8D%E6%82%A3%E8%80%85%E6%95%B0%E6%8D%AE%E5%91%8A%E8%AF%89%E4%BD%A0%E7%AD%94%E6%A1%88\"><\/span><strong>\u91cd\u78c5\uff1a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u80fd\u5426\u8c03\u63a7\u8840\u7cd6\uff1f7\u9879\u7814\u7a76\u3001413\u540d\u60a3\u8005\u6570\u636e\u544a\u8bc9\u4f60\u7b54\u6848<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3 class=\"ds-markdown-paragraph\"><span class=\"ez-toc-section\" id=\"%E7%A0%94%E7%A9%B6%E8%AE%BE%E8%AE%A1%E4%B8%8E%E6%96%B9%E6%B3%95\"><\/span><strong>\u7814\u7a76\u8bbe\u8ba1\u4e0e\u65b9\u6cd5<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\">\u672c\u7814\u7a76\u91c7\u7528\u7cfb\u7edf\u7efc\u8ff0\u548c\u835f\u8403\u5206\u6790\uff0c\u4e25\u683c\u8bc4\u4f30\u4e86\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u7684\u7597\u6548\u4e0e\u5b89\u5168\u6027\u3002\u7814\u7a76\u56e2\u961f\u7cfb\u7edf\u68c0\u7d22\u4e86PubMed\u3001Web of Science\u3001Cochrane\u56fe\u4e66\u9986\u548cCNKI\u7b49\u6570\u636e\u5e93\uff0c\u65f6\u95f4\u8303\u56f4\u4ece\u5404\u6570\u636e\u5e93\u5efa\u5e93\u81f32020\u5e741\u67084\u65e5\uff0c\u68c0\u7d22\u7b56\u7565\u7ed3\u5408\u4e86\u201c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u201d\u3001\u201c\u7cd6\u5c3f\u75c5\u201d\u7b49\u4e2d\u82f1\u6587\u5173\u952e\u8bcd\u3002<\/p>\n<p class=\"ds-markdown-paragraph\">\u5728\u6587\u732e\u7b5b\u9009\u65b9\u9762\uff0c\u7814\u7a76\u5236\u5b9a\u4e86\u660e\u786e\u7684\u7eb3\u5165\u4e0e\u6392\u9664\u6807\u51c6\uff1a\u7eb3\u5165\u4efb\u4f55\u5e74\u9f84\u3001\u6027\u522b\u4e14\u65e0\u4e25\u91cd\u5e76\u53d1\u75c7\u7684\u7cd6\u5c3f\u75c5\u60a3\u8005\u53c2\u4e0e\u7684\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff0c\u8fd9\u4e9b\u8bd5\u9a8c\u9700\u5bf9\u6bd4MSCs\u4e0e\u5b89\u6170\u5242\u6216\u6807\u51c6\u6cbb\u7597\u7684\u6548\u679c\uff1b\u6392\u9664\u4e86\u975e\u4eba\u4f53\u7814\u7a76\u3001\u975e\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u53ca\u6570\u636e\u4e0d\u5168\u7684\u6587\u732e\u3002\u6574\u4e2a\u7b5b\u9009\u6d41\u7a0b\u4e25\u683c\u9075\u5faaPRISMA\u6307\u5357\uff0c\u5e76\u7531\u4e24\u4f4d\u7814\u7a76\u8005\u72ec\u7acb\u8fdb\u884c\u64cd\u4f5c\uff0c\u5982\u9047\u5206\u6b67\u5219\u7531\u7b2c\u4e09\u65b9\u4ef2\u88c1\uff0c\u4ee5\u786e\u4fdd\u5ba2\u89c2\u4e0e\u51c6\u786e\u3002<\/p>\n<p class=\"ds-markdown-paragraph\">\u6700\u7ec8\uff0c\u7814\u7a76\u4ece7\u9879\u7b26\u5408\u6807\u51c6\u7684\u8bd5\u9a8c\u4e2d\u63d0\u53d6\u5e76\u5206\u6790\u4e86\u6570\u636e\uff0c\u4e3b\u8981\u89c2\u6d4b\u6307\u6807\u4e3a\u6cbb\u7597\u524d\u540e\u7a7a\u8179\u8840\u7cd6\u3001\u7cd6\u5316\u8840\u7ea2\u86cb\u767d\u548c\u7a7a\u8179C\u80bd\u6c34\u5e73\u7684\u53d8\u5316\uff0c\u540c\u65f6\u5c06\u4f4e\u8840\u7cd6\u3001\u6dc0\u7c89\u9176\u5f02\u5e38\u7b49\u4e0d\u826f\u4e8b\u4ef6\u4f5c\u4e3a\u6b21\u8981\u7ed3\u679c\u8fdb\u884c\u8bc4\u4f30\uff0c\u4ee5\u6b64\u5168\u9762\u5ba1\u89c6MSCs\u7597\u6cd5\u7684\u4e34\u5e8a\u4ef7\u503c\u4e0e\u98ce\u9669\u3002<\/p>\n<h1 id=\"artTitle\"><span class=\"ez-toc-section\" id=\"%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B3%96%E5%B0%BF%E7%97%85%E6%82%A3%E8%80%85%E8%A1%80%E7%B3%96%E6%8E%A7%E5%88%B6%E7%9A%84%E4%B8%B4%E5%BA%8A%E7%96%97%E6%95%88%E5%8F%8A%E5%AE%89%E5%85%A8%E6%80%A7%E7%9A%84%E7%BB%93%E6%9E%9C\"><\/span><span dir=\"auto\">\u5e72\u7ec6\u80de\u6cbb\u7597\u7cd6\u5c3f\u75c5\u60a3\u8005\u8840\u7cd6\u63a7\u5236\u7684\u4e34\u5e8a\u7597\u6548\u53ca\u5b89\u5168\u6027\u7684<\/span><span dir=\"auto\">\u7ed3\u679c<\/span><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<h3><span class=\"ez-toc-section\" id=\"%E8%AF%95%E9%AA%8C%E9%80%89%E6%8B%A9%E5%92%8C%E5%9F%BA%E6%9C%AC%E7%89%B9%E5%BE%81\"><\/span><span dir=\"auto\">\u8bd5\u9a8c\u9009\u62e9\u548c\u57fa\u672c\u7279\u5f81<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\">\u7ecf\u8fc7\u7cfb\u7edf\u68c0\u7d22\u548c\u4e25\u683c\u7b5b\u9009\uff0c\u4ece\u521d\u59cb\u68c0\u7d22\u5230\u7684<strong>1372\u7bc7\u6587\u732e<\/strong>\u4e2d\uff0c\u901a\u8fc7\u53bb\u91cd\u548c\u9898\u76ee\u6458\u8981\u7b5b\u9009\u540e\u5269\u4f59<strong>176\u7bc7<\/strong>\u8fdb\u5165\u5168\u6587\u8bc4\u4f30\u3002\u5728\u5168\u6587\u8bc4\u4f30\u9636\u6bb5\uff0c<strong>169\u9879\u7814\u7a76<\/strong>\u56e0\u975e\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\u3001\u975e\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff08RCT\uff09\u6216\u60a3\u8005\u5408\u5e76\u591a\u79cd2\u578b\u7cd6\u5c3f\u75c5\u5e76\u53d1\u75c7\u800c\u88ab\u6392\u9664\u3002\u968f\u540e\uff0c<strong>\u53e6\u67093\u9879\u7814\u7a76<\/strong>\u56e0\u540c\u65f6\u4f7f\u7528\u4e86\u5176\u4ed6\u5e72\u7ec6\u80de\u4e14\u672a\u63d0\u4f9b\u53ef\u7528\u6570\u636e\u800c\u88ab\u6392\u9664\u3002\u6700\u7ec8\uff0c\u5171\u6709<strong>7\u9879RCT<\/strong>\u7b26\u5408\u7eb3\u5165\u835f\u8403\u5206\u6790\u7684\u6761\u4ef6\uff08\u56fe1\uff09\u3002<\/p>\n<div id=\"attachment_20195\" style=\"width: 330px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20195\" class=\"wp-image-20195 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g001.png\" alt=\"\u56fe 1.\u7814\u7a76\u8bc6\u522b\u3001\u7b5b\u9009\u548c\u7eb3\u5165\u8fc7\u7a0b\u7684\u6d41\u7a0b\u56fe\u3002\" width=\"320\" height=\"620\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g001.png 320w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g001-155x300.png 155w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g001-6x12.png 6w\" sizes=\"(max-width: 320px) 100vw, 320px\" \/><p id=\"caption-attachment-20195\" class=\"wp-caption-text\">\u56fe 1.\u7814\u7a76\u8bc6\u522b\u3001\u7b5b\u9009\u548c\u7eb3\u5165\u8fc7\u7a0b\u7684\u6d41\u7a0b\u56fe\u3002<\/p><\/div>\n<h3><span class=\"ez-toc-section\" id=\"%E7%A0%94%E7%A9%B6%E7%89%B9%E5%BE%81\"><\/span><span dir=\"auto\">\u7814\u7a76\u7279\u5f81<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\">\u8fd9<strong>7\u9879\u7814\u7a76<\/strong>\u5171\u6d89\u53ca<strong>413\u540d\u53d7\u8bd5\u8005<\/strong>\uff0c\u5176\u4e2d<strong>207\u540d\uff0850.1%\uff09<\/strong>\u00a0\u63a5\u53d7\u4e86\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u3002\u7814\u7a76\u5730\u70b9\u5206\u5e03\u4e3a\uff1a<strong>5\u9879\u5728\u4e2d\u56fd<\/strong>(math.) genus<strong>1\u9879\u5728\u5370\u5ea6<\/strong>(math.) genus<strong>1\u9879\u5728\u745e\u5178<\/strong>The<\/p>\n<p class=\"ds-markdown-paragraph\">\u53d7\u8bd5\u8005\u7684\u5e73\u5747\u5e74\u9f84\u8303\u56f4\u5728<strong>17.6\u5c81\u81f357.6\u5c81<\/strong>\u4e4b\u95f4\uff0c\u4e14\u4ee5\u7537\u6027\u4e3a\u4e3b\u3002\u6240\u4f7f\u7528\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7c7b\u578b\u5305\u62ec<strong>\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08BM-MSCs\uff09\u3001\u534e\u901a\u6c0f\u80f6\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08WJ-MSCs\uff09\u3001\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08UC-MSCs\uff09\u548c\u7f8a\u819c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08AMSCs\uff09<\/strong>\uff0c\u6240\u6709\u7814\u7a76\u7684\u7ec6\u80de\u8f93\u6ce8\u5242\u91cf\u5747\u00a0<strong>&gt; 1.0\u00d710\u2077 cells\/kg<\/strong>\u3002\u5728\u7814\u7a76\u7126\u70b9\u4e0a\uff0c<strong>2\u9879\u7814\u7a76<\/strong>\u9488\u5bf91\u578b\u7cd6\u5c3f\u75c5\uff0c<strong>5\u9879\u7814\u7a76<\/strong>\u9488\u5bf92\u578b\u7cd6\u5c3f\u75c5\u3002\u5bf9\u7167\u7ec4\u5206\u522b\u91c7\u7528<strong>\u5b89\u6170\u5242\u3001\u5047\u624b\u672f\u6216\u4e0d\u63a5\u53d7\u4efb\u4f55\u6cbb\u7597<\/strong>\u3002\u5728\u6570\u636e\u62a5\u544a\u65b9\u9762\uff0c<strong>1\u9879\u7814\u7a76<\/strong>\u4ec5\u62a5\u544a\u4e2d\u4f4d\u6570\u548c\u6781\u503c\uff0c<strong>2\u9879\u7814\u7a76<\/strong>\u62a5\u544a\u5747\u503c\u548c\u6807\u51c6\u8bef\uff0c\u5728\u65e0\u6cd5\u8054\u7cfb\u4f5c\u8005\u7684\u60c5\u51b5\u4e0b\uff0c\u7814\u7a76\u56e2\u961f\u91c7\u7528\u4e86\u7edf\u8ba1\u65b9\u6cd5\u8fdb\u884c\u6570\u636e\u8f6c\u6362\u548c\u5355\u4f4d\u7edf\u4e00\u4ee5\u8fdb\u884c\u540e\u7eed\u5206\u6790\u3002<\/p>\n<h1 id=\"artTitle\"><span class=\"ez-toc-section\" id=\"%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97413%E5%90%8D%E7%B3%96%E5%B0%BF%E7%97%85%E6%82%A3%E8%80%85%E8%A1%80%E7%B3%96%E6%8E%A7%E5%88%B6%E7%9A%84%E6%95%88%E6%9E%9C\"><\/span><span dir=\"auto\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597413\u540d\u7cd6\u5c3f\u75c5\u60a3\u8005<\/span><span dir=\"auto\">\u8840\u7cd6\u63a7\u5236\u7684\u6548\u679c<\/span><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p><span dir=\"auto\">\u6bd4\u8f83\u6cbb\u7597\u524d\u540e\u6216 MSC \u6cbb\u7597\u7ec4\u548c\u5bf9\u7167\u7ec4\u7684 FPG\u3001HbA1c \u548c\u7a7a\u8179 C \u80bd\u6c34\u5e73\u7684\u5e73\u5747\u503c\u548c\u6807\u51c6\u5dee\u3002<\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"1_FPG%EF%BC%88%E7%A9%BA%E8%85%B9%E8%A1%80%E7%B3%96%EF%BC%89\"><\/span>1. FPG\uff08\u7a7a\u8179\u8840\u7cd6\uff09<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u603b\u4f53\u6548\u679c<\/strong>\uff1aMSCs\u6cbb\u7597\u540e\uff0cFPG\u7684\u964d\u4f4e\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\u65e0\u663e\u8457\u5dee\u5f02\u3002\u8fd9\u610f\u5473\u7740MSCs\u6cbb\u7597\u5728\u77ed\u671f\u8840\u7cd6\u63a7\u5236\u65b9\u9762\u6ca1\u6709\u663e\u793a\u51fa\u660e\u663e\u6539\u5584\uff08\u56fe2\uff09\u3002<\/p>\n<div id=\"attachment_20200\" style=\"width: 2010px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20200\" class=\"wp-image-20200 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g002.png\" alt=\"\u56fe2. FPG (mmol\/l) \u7684\u68ee\u6797\u56fe\u3002\" width=\"2000\" height=\"991\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g002.png 2000w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g002-300x149.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g002-1024x507.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g002-768x381.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g002-1536x761.png 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g002-18x9.png 18w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/><p id=\"caption-attachment-20200\" class=\"wp-caption-text\">\u56fe 2. FPG (mmol\/l) \u7684\u68ee\u6797\u56fe\u3002<\/p><\/div>\n<p class=\"ds-markdown-paragraph\"><strong>\u5177\u4f53\u6570\u636e<\/strong>\uff1a\u5728\u6cbb\u7597\u524d\u540e\u6bd4\u8f83\u4e2d\uff0c\u5408\u5e76\u5747\u503c\u5dee\uff08MD\uff09\u4e3a-1.05 mg\/dL\uff0c95%\u7f6e\u4fe1\u533a\u95f4\uff08-2.26, 0.16\uff09\uff0cP&lt;0.01\uff0c\u4f46\u7f6e\u4fe1\u533a\u95f4\u5305\u542b0\uff0c\u8868\u660e\u65e0\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u3002\u5728MSCs\u6cbb\u7597\u7ec4\u4e0e\u5bf9\u7167\u7ec4\u6bd4\u8f83\u4e2d\uff0c\u5408\u5e76MD\u4e3a-0.62 mg\/dL\uff0c95%\u7f6e\u4fe1\u533a\u95f4\uff08-1.46, 0.23\uff09\uff0cP&lt;0.01\uff0c\u540c\u6837\u7f6e\u4fe1\u533a\u95f4\u5305\u542b0\uff0c\u65e0\u663e\u8457\u5dee\u5f02\uff08\u56fe3\uff09\u3002<\/p>\n<div id=\"attachment_20199\" style=\"width: 1807px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20199\" class=\"wp-image-20199 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g003.png\" alt=\"\u56fe3. FPG (mmol\/l) \u4e9a\u7ec4\u5206\u6790\u7684\u68ee\u6797\u56fe\u3002\" width=\"1797\" height=\"2400\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g003.png 1797w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g003-225x300.png 225w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g003-767x1024.png 767w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g003-768x1026.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g003-1150x1536.png 1150w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g003-1533x2048.png 1533w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g003-9x12.png 9w\" sizes=\"(max-width: 1797px) 100vw, 1797px\" \/><p id=\"caption-attachment-20199\" class=\"wp-caption-text\">\u56fe 3. FPG (mmol\/l) \u4e9a\u7ec4\u5206\u6790\u7684\u68ee\u6797\u56fe\u3002<\/p><\/div>\n<p class=\"ds-markdown-paragraph\"><strong>\u4e9a\u7ec4\u5206\u6790<\/strong>\uff1a\u77ed\u671f\u968f\u8bbf\uff08\u4e0d\u8db36\u4e2a\u6708\uff09\u6216\u4e2d\u56fd\u7814\u7a76\u4e2d\u53ef\u80fd\u663e\u793aFPG\u6539\u5584\uff0c\u4f46\u8fd9\u4e9b\u7ed3\u679c\u9700\u8981\u66f4\u591a\u7814\u7a76\u8bc1\u5b9e\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"2_HbA1c%EF%BC%88%E7%B3%96%E5%8C%96%E8%A1%80%E7%BA%A2%E8%9B%8B%E7%99%BD%EF%BC%89\"><\/span>2. HbA1c\uff08\u7cd6\u5316\u8840\u7ea2\u86cb\u767d\uff09<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u603b\u4f53\u6548\u679c<\/strong>\uff1aMSCs\u6cbb\u7597\u540e\uff0cHbA1c\u6c34\u5e73\u663e\u8457\u964d\u4f4e\u3002\u8fd9\u8868\u660eMSCs\u6cbb\u7597\u5728\u957f\u671f\u8840\u7cd6\u63a7\u5236\uff08\u8fc7\u53bb2-3\u4e2a\u6708\u7684\u5e73\u5747\u8840\u7cd6\u6c34\u5e73\uff09\u65b9\u9762\u6709\u79ef\u6781\u6548\u679c\uff08\u56fe4\uff09\u3002<\/p>\n<div id=\"attachment_20198\" style=\"width: 2010px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20198\" class=\"wp-image-20198 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g004.png\" alt=\"\u56fe4. HbA1c (%) \u7684\u68ee\u6797\u56fe\u3002\" width=\"2000\" height=\"1434\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g004.png 2000w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g004-300x215.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g004-1024x734.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g004-768x551.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g004-1536x1101.png 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g004-18x12.png 18w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/><p id=\"caption-attachment-20198\" class=\"wp-caption-text\">\u56fe 4. HbA1c (%) \u7684\u68ee\u6797\u56fe\u3002<\/p><\/div>\n<p class=\"ds-markdown-paragraph\"><strong>\u5177\u4f53\u6570\u636e<\/strong>\uff1a\u5728\u6cbb\u7597\u524d\u540e\u6bd4\u8f83\u4e2d\uff0c\u5408\u5e76MD\u4e3a-1.32%\uff0c95%\u7f6e\u4fe1\u533a\u95f4\uff08-2.06, -0.57\uff09\uff0cP&lt;0.01\uff0c\u7f6e\u4fe1\u533a\u95f4\u4e0d\u5305\u542b0\uff0c\u8868\u660e\u964d\u4f4e\u5177\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u3002\u5728MSCs\u6cbb\u7597\u7ec4\u4e0e\u5bf9\u7167\u7ec4\u6bd4\u8f83\u4e2d\uff0c\u5408\u5e76MD\u4e3a-0.87%\uff0c95%\u7f6e\u4fe1\u533a\u95f4\uff08-1.53, -0.22\uff09\uff0cP&lt;0.01\uff0c\u7f6e\u4fe1\u533a\u95f4\u4e0d\u5305\u542b0\uff0c\u8868\u660e\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0cHbA1c\u663e\u8457\u964d\u4f4e\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"3_%E7%A9%BA%E8%85%B9C%E8%82%BD\"><\/span>3. \u7a7a\u8179C\u80bd<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u603b\u4f53\u6548\u679c<\/strong>\uff1aMSCs\u6cbb\u7597\u540e\uff0c\u7a7a\u8179C\u80bd\u6c34\u5e73\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\u65e0\u663e\u8457\u5dee\u5f02\u3002\u7a7a\u8179C\u80bd\u53cd\u6620\u80f0\u5c9b\u7d20\u5206\u6ccc\u529f\u80fd\uff0c\u65e0\u663e\u8457\u53d8\u5316\u8868\u660eMSCs\u6cbb\u7597\u53ef\u80fd\u672a\u660e\u663e\u6539\u5584\u80f0\u5c9b\u03b2\u7ec6\u80de\u529f\u80fd\u3002<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u5177\u4f53\u6570\u636e<\/strong>\uff1a\u5728MSCs\u6cbb\u7597\u7ec4\u4e0e\u5bf9\u7167\u7ec4\u6bd4\u8f83\u4e2d\uff0c\u5408\u5e76MD\u4e3a-0.07 ng\/mL\uff0c95%\u7f6e\u4fe1\u533a\u95f4\uff08-0.30, 0.16\uff09\uff0cP&lt;0.01\uff0c\u7f6e\u4fe1\u533a\u95f4\u5305\u542b0\uff0c\u8868\u660e\u65e0\u7edf\u8ba1\u5b66\u663e\u8457\u6027\u3002\u4e2a\u522b\u7814\u7a76\u7ed3\u679c\u4e0d\u4e00\u81f4\uff08\u6709\u7684\u663e\u793a\u964d\u4f4e\uff0c\u6709\u7684\u663e\u793a\u5347\u9ad8\uff09\uff0c\u4f46\u603b\u4f53\u5408\u5e76\u540e\u65e0\u663e\u8457\u5dee\u5f02\uff08\u56fe5\uff09\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-20197 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g005.png\" alt=\"\u56fe 5.\u7a7a\u8179 C \u80bd (nmol\/L) \u7684\u68ee\u6797\u56fe\u3002\" width=\"2000\" height=\"410\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g005.png 2000w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g005-300x62.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g005-1024x210.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g005-768x157.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g005-1536x315.png 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g005-18x4.png 18w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/><\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E7%BB%93%E8%AE%BA\"><\/span>reach a verdict<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\">\u7efc\u5408\u6765\u770b\uff0c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u5bf9\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u8840\u7cd6\u63a7\u5236\u6548\u679c\uff1a<\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>HbA1c\u663e\u8457\u6539\u5584<\/strong>\uff0c\u8bf4\u660e\u957f\u671f\u8840\u7cd6\u63a7\u5236\u5f97\u5230\u589e\u5f3a\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>FPG\u548c\u7a7a\u8179C\u80bd\u65e0\u663e\u8457\u6539\u5584<\/strong>\uff0c\u8bf4\u660e\u77ed\u671f\u8840\u7cd6\u63a7\u5236\u548c\u80f0\u5c9b\u7d20\u5206\u6ccc\u529f\u80fd\u53ef\u80fd\u672a\u660e\u663e\u6062\u590d\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\">\u8fd9\u4e9b\u7ed3\u679c\u57fa\u4e8e\u73b0\u6709\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4f46\u5f02\u8d28\u6027\u8f83\u9ad8\uff08I\u00b2\u503c\u5747\u5927\u4e8e80%\uff09\uff0c\u8868\u660e\u7814\u7a76\u95f4\u5b58\u5728\u8f83\u5927\u53d8\u5f02\uff0c\u9700\u8981\u66f4\u591a\u9ad8\u8d28\u91cf\u7814\u7a76\u6765\u9a8c\u8bc1\u3002<\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"ez-toc-section\" id=\"%E5%AE%89%E5%85%A8%E7%BB%93%E6%9E%9C\"><\/span><span dir=\"auto\">\u5b89\u5168\u7ed3\u679c<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\">\u5171\u62a5\u544a\u4e866\u9879\u8bd5\u9a8c\u548c66\u4f8b\u4e0d\u826f\u53cd\u5e94\uff0c\u5176\u4e2d33\u4f8b\u6765\u81eaMSCs\u6cbb\u7597\u7ec4\u3002\u5728\u8fd933\u4f8b\u4e0d\u826f\u53cd\u5e94\u4e2d\uff0c\u67092\u9879\u8bd5\u9a8c\u672a\u53d1\u751f\u4e0d\u826f\u4e8b\u4ef6\uff0c\u56e0\u6b64\u672a\u5728\u68ee\u6797\u56fe\u4e2d\u663e\u793a\u3002\u5728\u7eb3\u5165\u7684\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u4e2d\uff0c\u968f\u8bbf\u671f\u95f4\u672a\u53d1\u751f\u4e0eMSCs\u6cbb\u7597\u76f8\u5173\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002\u8fd9\u4e9b\u4e0d\u826f\u53cd\u5e94\u8f83\u8f7b\uff0c\u5305\u62ec\u4f4e\u8840\u7cd6\u3001\u6dc0\u7c89\u9176\u5f02\u5e38\u548c\u916e\u75c7\u9178\u4e2d\u6bd2\u3002\u4e24\u7ec4\u95f4\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\u65e0\u7edf\u8ba1\u5b66\u5dee\u5f02[RR = 0.98\uff0c95%CI (0.72, 1.32)\uff0cP = 0.02\uff0cI\u00b2\u00a0<\/span><sup><span dir=\"auto\">=<\/span><\/sup><span dir=\"auto\">\u00a070%]\uff08<\/span><span dir=\"auto\">Figure 6<\/span><span dir=\"auto\">\uff09\u3002<\/span><\/p>\n<div id=\"attachment_20196\" style=\"width: 2010px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20196\" class=\"wp-image-20196 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g006.png\" alt=\"\u56fe6. MSCs \u6cbb\u7597\u7ec4\u548c\u5bf9\u7167\u7ec4\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\u7684\u68ee\u6797\u56fe\u3002\" width=\"2000\" height=\"492\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g006.png 2000w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g006-300x74.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g006-1024x252.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g006-768x189.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g006-1536x378.png 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/10\/journal.pone_.0247662.g006-18x4.png 18w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/><p id=\"caption-attachment-20196\" class=\"wp-caption-text\">\u56fe 6. MSCs \u6cbb\u7597\u7ec4\u548c\u5bf9\u7167\u7ec4\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\u7684\u68ee\u6797\u56fe\u3002<\/p><\/div>\n<p>MSC\u6cbb\u7597\u7ec4\u4e2d\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94\u662f\u4f4e\u8840\u7cd6\uff0829.95%\uff09\u3002\u5f02\u8d28\u6027\u8f83\u4f4e\uff0c\u8868\u660e\u5b89\u5168\u6027\u826f\u597d\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E8%AE%A8%E8%AE%BA\"><\/span><span dir=\"auto\">\u8ba8\u8bba<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span dir=\"auto\">\u672c\u835f\u8403\u5206\u6790\u65e8\u5728\u8bc4\u4f30\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u6cbb\u7597\u7cd6\u5c3f\u75c5\uff08DM\uff09\u7684\u4e34\u5e8a\u6570\u636e\uff0c\u5e76\u6c47\u603b\u7edf\u8ba1\u6570\u636e\uff0c\u4ee5\u671f\u6539\u5584\u8840\u7cd6\u63a7\u5236\uff0c\u5e76\u4e3a\u8be5\u7597\u6cd5\u63d0\u4f9b\u5faa\u8bc1\u4e14\u7ecf\u6d4e\u6709\u6548\u7684\u533b\u7597\u65b9\u6848\u3002\u5df2\u6709\u6570\u9879\u7814\u7a76\u8bc4\u4f30\u4e86\u5e72\u7ec6\u80de\u7597\u6cd5\u5728\u7cd6\u5c3f\u75c5\u6cbb\u7597\u4e2d\u7684\u6f5c\u529b\uff0c\u4f46\u7ed3\u679c\u5e76\u4e0d\u4e00\u81f4\u3002\u6211\u4eec\u7684\u5206\u6790\u663e\u793a\uff0cMSC\u8f93\u6ce8\u53ef\u663e\u8457\u6539\u5584\u7cd6\u5316\u8840\u7ea2\u86cb\u767d\uff08HbA1c\uff09\u6c34\u5e73\uff0c\u5c3d\u7ba1\u57281\u578b\u7cd6\u5c3f\u75c5\uff08T1DM\uff09\u548c2\u578b\u7cd6\u5c3f\u75c5\uff08T2DM\uff09\u60a3\u8005\u4e2d\uff0c\u7a7a\u8179\u8840\u7cd6\uff08FPG\uff09\u548c\u7a7a\u8179C\u80bd\u6c34\u5e73\u65e0\u663e\u8457\u5dee\u5f02\u3002\u6b64\u5916\uff0c\u4e24\u7ec4\u60a3\u8005\u7684\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u4e5f\u65e0\u663e\u8457\u5dee\u5f02\u3002\u7efc\u4e0a\u6240\u8ff0\uff0c\u672c\u835f\u8403\u5206\u6790\u8868\u660e\uff0c\u57fa\u4e8eMSC\u7684\u5e72\u7ec6\u80de\u7597\u6cd5\u5177\u6709\u826f\u597d\u7684\u5b89\u5168\u6027\uff0c\u80fd\u591f\u6539\u5584\u8840\u7cd6\u63a7\u5236\uff0c\u5e76\u53ef\u80fd\u6210\u4e3a\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u4e00\u79cd\u66ff\u4ee3\u6cbb\u7597\u65b9\u6848\u3002<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E7%BB%93%E8%AE%BA-2\"><\/span><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">reach a verdict<\/span><\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span 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