{"id":20341,"date":"2025-11-10T18:02:02","date_gmt":"2025-11-10T10:02:02","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=20341"},"modified":"2025-11-10T18:02:02","modified_gmt":"2025-11-10T10:02:02","slug":"%e5%b9%b2%e7%bb%86%e8%83%9e%e6%b2%bb%e7%96%97%e8%82%be%e7%97%85","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20341.html","title":{"rendered":"\u540c\u6d4e\u533b\u9662\u62a5\u544a\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u80be\u75c5\u53ef\u51cf\u7f13CKD3\u20134\u671f\u60a3\u8005\u80be\u529f\u80fd\u4e0b\u964d\uff0c\u5e76\u4fdd\u5168\u80be\u529f\u80fd"},"content":{"rendered":"<p class=\"ds-markdown-paragraph\">\u521a\u521a\uff0c<a href=\"https:\/\/journals.lww.com\/jasn\/fulltext\/2025\/10001\/safety_and_efficacy_of_human_umbilical_cord.105.aspx\" target=\"_blank\" rel=\"noopener nofollow\">\u5728\u7f8e\u56fd\u80be\u810f\u75c5\u5b66\u4f1a2025\u5e74\u80be\u810f\u5468\uff08Kidney Week 2025\uff09\u4e0a<\/a>\uff0c\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u9662\u53d1\u5e03\u7684\u4e00\u9879\u53e3\u5934\u62a5\u544a\u5f15\u8d77\u5e7f\u6cdb\u5173\u6ce8\u3002\u7814\u7a76\u56e2\u961f\u516c\u5e03\u7684\u7ed3\u679c\u663e\u793a\uff1a\u4eba\u8110\u5e26<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/19975.html\/\" target=\"_blank\" rel=\"noopener\">mesenchymal stem cell MSC (in cell biology)<\/a>\uff08UC-MSC\uff09\u7ecf\u9759\u8109\u8f93\u6ce8\uff0c\u5728\u6162\u6027\u80be\u75c5\uff08CKD\uff093\u20134\u671f\u60a3\u8005\u4e2d\uff0c\u663e\u793a\u51fa\u80be\u529f\u80fd\u4fdd\u5168\u53ca\u86cb\u767d\u5c3f\u63a7\u5236\u7684\u79ef\u6781\u4fe1\u53f7\uff0c\u4e14\u5728\u4e00\u5e74\u968f\u8bbf\u671f\u95f4\u672a\u53d1\u751f\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002<\/p>\n<p>\u8fd9\u4e00\u53d1\u73b0\u4e3a\u957f\u671f\u7f3a\u4e4f\u6709\u6548\u5e72\u9884\u624b\u6bb5\u7684\u6162\u6027\u80be\u75c5\u7ba1\u7406\u63d0\u4f9b\u4e86\u65b0\u601d\u8def\u2014\u2014\u5728\u5e38\u89c4\u836f\u7269\u6cbb\u7597\u4e4b\u5916\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u80be\u75c5\u6709\u671b\u4e3a\u60a3\u8005\u4e89\u53d6\u66f4\u957f\u7684\u201c\u975e\u900f\u6790\u65f6\u95f4\u201d\uff0c\u5ef6\u7f13\u80be\u529f\u80fd\u8870\u9000\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20342 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/istockphoto-1285328928-612x612-1.jpg\" alt=\"\u540c\u6d4e\u533b\u9662\u62a5\u544a\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u80be\u75c5\u53ef\u51cf\u7f13CKD3\u20134\u671f\u60a3\u8005\u80be\u529f\u80fd\u4e0b\u964d\uff0c\u5e76\u4fdd\u5168\u80be\u529f\u80fd\" width=\"612\" height=\"408\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/istockphoto-1285328928-612x612-1.jpg 612w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/istockphoto-1285328928-612x612-1-300x200.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/istockphoto-1285328928-612x612-1-18x12.jpg 18w\" sizes=\"(max-width: 612px) 100vw, 612px\" \/><\/p>\n<hr \/>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20341.html\/#%E7%A0%94%E7%A9%B6%E8%AE%BE%E8%AE%A1%EF%BC%9A%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%82%BE%E7%97%85%E7%9A%84%E9%9A%8F%E6%9C%BA%E3%80%81%E5%8F%8C%E7%9B%B2%E3%80%81%E5%AE%89%E6%85%B0%E5%89%82%E5%AF%B9%E7%85%A7\" >\u7814\u7a76\u8bbe\u8ba1\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u80be\u75c5\u7684\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20341.html\/#%E6%95%B0%E6%8D%AE%E7%BB%93%E6%9E%9C%EF%BC%9A%E5%A4%9A%E9%A1%B9%E6%8C%87%E6%A0%87%E6%8F%90%E7%A4%BA%E8%82%BE%E5%8A%9F%E8%83%BD%E4%BF%9D%E5%85%A8\" >\u6570\u636e\u7ed3\u679c\uff1a\u591a\u9879\u6307\u6807\u63d0\u793a\u80be\u529f\u80fd\u4fdd\u5168<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20341.html\/#%E5%AE%89%E5%85%A8%E6%80%A7%E8%89%AF%E5%A5%BD%EF%BC%8C%E6%9C%AA%E5%8F%91%E7%94%9F%E4%B8%A5%E9%87%8D%E4%B8%8D%E8%89%AF%E4%BA%8B%E4%BB%B6\" >\u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u53d1\u751f\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20341.html\/#%E5%AF%B9%E6%82%A3%E8%80%85%E7%9A%84%E5%90%AF%E7%A4%BA%EF%BC%9A%E6%96%B0%E5%B8%8C%E6%9C%9B%EF%BC%8C%E6%96%B0%E9%80%89%E6%8B%A9\" >\u5bf9\u60a3\u8005\u7684\u542f\u793a\uff1a\u65b0\u5e0c\u671b\uff0c\u65b0\u9009\u62e9<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20341.html\/#%E7%A7%91%E5%AD%A6%E9%80%BB%E8%BE%91%EF%BC%9A%E4%BB%8E%E4%BF%AE%E5%A4%8D%E5%BE%AE%E7%8E%AF%E5%A2%83%E5%85%A5%E6%89%8B\" >\u79d1\u5b66\u903b\u8f91\uff1a\u4ece\u4fee\u590d\u5fae\u73af\u5883\u5165\u624b<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20341.html\/#%E5%B1%95%E6%9C%9B%EF%BC%9A%E4%BB%8E%E8%B6%8B%E5%8A%BF%E5%88%B0%E8%AF%81%E6%8D%AE%EF%BC%8C%E6%9C%AA%E6%9D%A5%E5%8F%AF%E6%9C%9F\" >\u5c55\u671b\uff1a\u4ece\u8d8b\u52bf\u5230\u8bc1\u636e\uff0c\u672a\u6765\u53ef\u671f<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%E7%A0%94%E7%A9%B6%E8%AE%BE%E8%AE%A1%EF%BC%9A%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%82%BE%E7%97%85%E7%9A%84%E9%9A%8F%E6%9C%BA%E3%80%81%E5%8F%8C%E7%9B%B2%E3%80%81%E5%AE%89%E6%85%B0%E5%89%82%E5%AF%B9%E7%85%A7\"><\/span>\u7814\u7a76\u8bbe\u8ba1\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u80be\u75c5\u7684\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p class=\"ds-markdown-paragraph\">\u8be5\u7814\u7a76\u5df2\u5728\u4e34\u5e8a\u6ce8\u518c\u5e73\u53f0\u767b\u8bb0\uff08\u7f16\u53f7 NCT05512988\uff09\uff0c\u91c7\u7528\u5355\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u8bbe\u8ba1\u3002\u5171\u7eb3\u516519\u4f8bCKD 3\u20134\u671f\u60a3\u8005\uff0c\u5176\u4e2d9\u4f8b\u63a5\u53d7UC-MSC\u6cbb\u7597\uff0c10\u4f8b\u4e3a\u5b89\u6170\u5242\u5bf9\u7167\u7ec4\uff0c\u6240\u6709\u60a3\u8005\u5747\u7ee7\u7eed\u63a5\u53d7\u6807\u51c6\u836f\u7269\u6cbb\u7597\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-20344 aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-10_174730_185.png\" alt=\"\" width=\"860\" height=\"459\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-10_174730_185.png 860w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-10_174730_185-300x160.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-10_174730_185-768x410.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-10_174730_185-18x10.png 18w\" sizes=\"(max-width: 860px) 100vw, 860px\" \/><\/p>\n<p class=\"ds-markdown-paragraph\">UC-MSC\u7ec4\u60a3\u8005\u63a5\u53d7\u4e24\u6b21\u9759\u8109\u8f93\u6ce8\uff0c\u5242\u91cf\u4e3a1\u00d710\u2076 cells\/kg\/\u6b21\uff0c\u95f4\u9694\u4e24\u5468\uff1b\u5bf9\u7167\u7ec4\u8f93\u6ce8\u7b49\u91cf\u5b89\u6170\u5242\u3002\u7814\u7a76\u56e2\u961f\u5728\u57fa\u7ebf\u53ca\u6cbb\u7597\u540e\u7b2c1\u30013\u30016\u30019\u300112\u4e2a\u6708\u8fdb\u884c\u968f\u8bbf\uff0c\u8bc4\u4f30\u80be\u529f\u80fd\u53d8\u5316\u4e0e\u5b89\u5168\u6027\u3002<\/p>\n<hr \/>\n<h2><span class=\"ez-toc-section\" id=\"%E6%95%B0%E6%8D%AE%E7%BB%93%E6%9E%9C%EF%BC%9A%E5%A4%9A%E9%A1%B9%E6%8C%87%E6%A0%87%E6%8F%90%E7%A4%BA%E8%82%BE%E5%8A%9F%E8%83%BD%E4%BF%9D%E5%85%A8\"><\/span>\u6570\u636e\u7ed3\u679c\uff1a\u591a\u9879\u6307\u6807\u63d0\u793a\u80be\u529f\u80fd\u4fdd\u5168<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff08eGFR\uff09<\/strong>\uff1aUC-MSC\u7ec4\u57286\u4e2a\u6708\u548c12\u4e2a\u6708\u65f6\u5747\u5448\u4e0a\u5347\u8d8b\u52bf\uff08\u5206\u522b\u589e\u52a01.5\u4e0e6.8 mL\/min\/1.73 m\u00b2\uff09\uff0c\u800c\u5bf9\u7167\u7ec4\u5728\u540c\u671f\u4ec5\u8868\u73b0\u4e3a\u8f7b\u5fae\u4e0b\u964d\u6216\u7f13\u6162\u4e0a\u5347\uff08-0.4\u4e0e+2.4\uff09\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u86cb\u767d\u5c3f\u63a7\u5236<\/strong>\uff1a\u5bf9\u7167\u7ec424\u5c0f\u65f6\u5c3f\u767d\u86cb\u767d\u6c34\u5e73\u968f\u65f6\u95f4\u4e0a\u5347\uff0c\u800cUC-MSC\u7ec4\u57fa\u672c\u7ef4\u6301\u7a33\u5b9a\u3002\u4e24\u7ec4\u5728\u7b2c9\u4e2a\u6708\u65f6\u5dee\u5f02\u5177\u6709\u7edf\u8ba1\u5b66\u610f\u4e49\uff08P\u22480.04\uff09\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u80f1\u6291\u7d20C<\/strong>\uff1aUC-MSC\u7ec4\u57286\u4e2a\u6708\u548c9\u4e2a\u6708\u65f6\u80f1\u6291\u7d20C\u6c34\u5e73\u663e\u8457\u4f18\u4e8e\u5bf9\u7167\u7ec4\uff08P\u503c\u5206\u522b\u4e3a0.011\u548c0.03\uff09\u3002<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u514d\u75ab\u8c03\u8282\u6548\u5e94<\/strong>\uff1aUC-MSC\u7ec4\u60a3\u8005NK\u7ec6\u80de\u6570\u91cf\u4fdd\u6301\u7a33\u5b9a\uff0c\u800c\u5bf9\u7167\u7ec4\u51fa\u73b0\u4e0b\u964d\uff0c\u4e24\u7ec4\u95f4\u5dee\u5f02\u663e\u8457\u3002<\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\">\u7814\u7a76\u56e2\u961f\u6307\u51fa\uff0c\u4e0a\u8ff0\u7ed3\u679c\u4e0e\u4eba\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6240\u5177\u6709\u7684\u6297\u708e\u3001\u6297\u7ea4\u7ef4\u5316\u53ca\u514d\u75ab\u8c03\u8282\u673a\u5236\u76f8\u7b26\uff0c\u63d0\u793a\u8be5\u7597\u6cd5\u53ef\u80fd\u6709\u52a9\u4e8e\u5ef6\u7f13\u80be\u529f\u80fd\u6301\u7eed\u6076\u5316\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-20343 aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-10_174740_880.png\" alt=\"\" width=\"1025\" height=\"596\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-10_174740_880.png 1025w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-10_174740_880-300x174.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-10_174740_880-768x447.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-10_174740_880-18x10.png 18w\" sizes=\"(max-width: 1025px) 100vw, 1025px\" \/><\/p>\n<hr \/>\n<h2><span class=\"ez-toc-section\" id=\"%E5%AE%89%E5%85%A8%E6%80%A7%E8%89%AF%E5%A5%BD%EF%BC%8C%E6%9C%AA%E5%8F%91%E7%94%9F%E4%B8%A5%E9%87%8D%E4%B8%8D%E8%89%AF%E4%BA%8B%E4%BB%B6\"><\/span>\u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u53d1\u751f\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p 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