{"id":20479,"date":"2025-11-14T16:09:45","date_gmt":"2025-11-14T08:09:45","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=20479"},"modified":"2025-11-14T16:09:45","modified_gmt":"2025-11-14T08:09:45","slug":"%e9%97%b4%e5%85%85%e8%b4%a8%e5%b9%b2%e7%bb%86%e8%83%9e%e6%b2%bb%e7%96%97%e8%86%9d%e9%aa%a8%e5%85%b3%e8%8a%82%e7%82%8e","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20479.html","title":{"rendered":"\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u7ec6\u80de\u5242\u91cf\u8981\u591a\u4e00\u70b9\u8fd8\u662f\u5c11\u4e00\u70b9\uff1f"},"content":{"rendered":"<p><a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20012.html\/\" target=\"_blank\" rel=\"noopener\">Osteoarthritis of the knee (OA)<\/a>\u662f\u4e00\u79cd\u9ad8\u53d1\u7684\u9000\u884c\u6027\u5173\u8282\u75be\u75c5\uff0c\u4e5f\u662f\u5168\u7403\u75bc\u75db\u548c\u6b8b\u75be\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\uff0c\u5f71\u54cd\u7740\u7ea66.54\u4ebf40\u5c81\u53ca\u4ee5\u4e0a\u7684\u4eba\u7fa4\u3002\u4eba\u53e3\u8001\u9f84\u5316\u548c\u80a5\u80d6\u7387\u4e0a\u5347\u662f\u5bfc\u81f4\u5176\u60a3\u75c5\u7387\u4e0d\u65ad\u589e\u957f\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u5e76\u9020\u6210\u4e86\u5de8\u5927\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff08OA\uff09\u7684\u4e00\u79cd\u5f88\u6709\u524d\u666f\u7684\u7597\u6cd5\u3002\u7136\u800c\uff0c\u5982\u4f55\u786e\u5b9a\u6700\u4f73\u7ec6\u80de\u5242\u91cf\u4ee5\u6700\u5927\u7a0b\u5ea6\u5730\u53d1\u6325\u4e34\u5e8a\u7597\u6548\u4ecd\u5b58\u5728\u4e0d\u786e\u5b9a\u6027\u3002<strong>\u672c\u7cfb\u7edf\u8bc4\u4ef7\u548c\u835f\u8403\u5206\u6790\u65e8\u5728\u8bc4\u4f30\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\u7684\u7597\u6548\uff0c\u5e76\u63a2\u8ba8\u7ec6\u80de\u5242\u91cf\u4e0e\u6cbb\u7597\u7ed3\u679c\u4e4b\u95f4\u7684\u5173\u7cfb\u3002<\/strong><\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20479.html\/#%E5%85%B3%E8%8A%82%E5%86%85%E6%B3%A8%E5%B0%84%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%86%9D%E9%AA%A8%E5%85%B3%E8%8A%82%E7%82%8E%EF%BC%9A%E7%BB%86%E8%83%9E%E5%89%82%E9%87%8F%E8%A6%81%E5%A4%9A%E4%B8%80%E7%82%B9%E8%BF%98%E6%98%AF%E5%B0%91%E4%B8%80%E7%82%B9%EF%BC%9F\" >\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u7ec6\u80de\u5242\u91cf\u8981\u591a\u4e00\u70b9\u8fd8\u662f\u5c11\u4e00\u70b9\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20479.html\/#%E6%96%B9%E6%B3%95\" >\u65b9\u6cd5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20479.html\/#%E7%BB%93%E6%9E%9C\" >\u7ed3\u679c<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20479.html\/#%E4%B8%BB%E8%A6%81%E7%BB%93%E5%B1%80%EF%BC%9A12%E4%B8%AA%E6%9C%88WOMAC%E8%AF%84%E5%88%86\" >\u4e3b\u8981\u7ed3\u5c40\uff1a12\u4e2a\u6708WOMAC\u8bc4\u5206<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20479.html\/#%E6%A3%AE%E6%9E%97%E5%9B%BE\" >\u68ee\u6797\u56fe<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20479.html\/#%E5%89%82%E9%87%8F-%E6%95%88%E5%BA%94%E5%85%B3%E7%B3%BB%E5%88%86%E6%9E%90\" >\u5242\u91cf-\u6548\u5e94\u5173\u7cfb\u5206\u6790<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20479.html\/#%E8%AE%A8%E8%AE%BA\" >\u8ba8\u8bba<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20479.html\/#%E7%BB%93%E8%AE%BA\" >reach a verdict<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%E5%85%B3%E8%8A%82%E5%86%85%E6%B3%A8%E5%B0%84%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%86%9D%E9%AA%A8%E5%85%B3%E8%8A%82%E7%82%8E%EF%BC%9A%E7%BB%86%E8%83%9E%E5%89%82%E9%87%8F%E8%A6%81%E5%A4%9A%E4%B8%80%E7%82%B9%E8%BF%98%E6%98%AF%E5%B0%91%E4%B8%80%E7%82%B9%EF%BC%9F\"><\/span>\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u7ec6\u80de\u5242\u91cf\u8981\u591a\u4e00\u70b9\u8fd8\u662f\u5c11\u4e00\u70b9\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u8fd1\u671f\uff0c\u300a<a class=\"c-breadcrumbs__link\" href=\"https:\/\/link.springer.com\/journal\/13018\" data-track=\"click_breadcrumb\" data-track-context=\"article page\" data-track-category=\"article\" data-track-action=\"breadcrumbs\" data-track-label=\"breadcrumb2\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\">\u9aa8\u79d1\u624b\u672f\u4e0e\u7814\u7a76\u6742\u5fd7<\/span><\/a>\u300b\u671f\u520a\u6742\u5fd7\u53d1\u8868\u4e86\u4e00\u7bc7\u201c<span dir=\"auto\"><a href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#Fig2\" target=\"_blank\" rel=\"noopener nofollow\">\u5355\u6b21\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\u7684\u7597\u6548\uff1a\u4e00\u9879\u4ee5\u5242\u91cf\u4e3a\u91cd\u70b9\u7684\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u835f\u8403\u5206\u6790<\/a>\u201d\uff0c\u8fd9\u7bc7\u7efc\u8ff0\u7ed3\u679c\u8868\u660e\uff1a\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u7597\u6cd5\u572812\u4e2a\u6708\u65f6\u663e\u8457\u6539\u5584\u4e86\u819d\u9aa8\u5173\u8282\u708e\u7684\u4e34\u5e8a\u7597\u6548\uff0c\u4e14\u8f83\u4f4e\u5242\u91cf\uff08\u22642500\u4e07\u4e2a\u7ec6\u80de\uff09\u4f3c\u4e4e\u65e2\u6709\u6548\u53c8\u53ef\u80fd\u66f4\u9ad8\u6548\u3002\u8fd9\u4e9b\u53d1\u73b0\u8868\u660e\uff0c\u5242\u91cf\u4f18\u5316\u662f\u63a8\u8fdbMSC\u7597\u6cd5\u53d1\u5c55\u7684\u5173\u952e\u8003\u8651\u56e0\u7d20\u3002<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20480 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/ScreenShot_2025-11-14_150717_159.png\" alt=\"\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u7ec6\u80de\u5242\u91cf\u8981\u591a\u4e00\u70b9\u8fd8\u662f\u5c11\u4e00\u70b9\uff1f\" width=\"702\" height=\"324\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/ScreenShot_2025-11-14_150717_159.png 702w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/ScreenShot_2025-11-14_150717_159-300x138.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/ScreenShot_2025-11-14_150717_159-18x8.png 18w\" sizes=\"(max-width: 702px) 100vw, 702px\" \/><\/p>\n<h2 data-spm-anchor-id=\"5176.28103460.0.i50.39367551ItdekH\"><span class=\"ez-toc-section\" id=\"%E6%96%B9%E6%B3%95\"><\/span>\u65b9\u6cd5<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>\u6587\u732e\u68c0\u7d22\u7b56\u7565\uff1a<\/strong>\u6211\u4eec\u5bf9PubMed\u548cScopus\u6570\u636e\u5e93\u4e2d2015\u5e74\u81f32025\u5e74\u95f4\u53d1\u8868\u7684\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff08RCT\uff09\u8fdb\u884c\u4e86\u5168\u9762\u7684\u6587\u732e\u68c0\u7d22\u3002\u68c0\u7d22\u7b56\u7565\u7ed3\u5408\u4e86\u5173\u952e\u8bcd\u548c\u533b\u5b66\u4e3b\u9898\u8bcd\uff08MeSH\uff09\uff0c\u5305\u62ec&#8221;mesenchymal stem cells&#8221;\u3001&#8221;bone marrow stromal cells&#8221;\u3001&#8221;knee osteoarthritis&#8221;\u3001&#8221;intra-articular injection&#8221;\u7b49\u3002\u6b64\u5916\uff0c\u6211\u4eec\u624b\u52a8\u68c0\u7d22\u4e86\u76f8\u5173\u7efc\u8ff0\u548c\u7eb3\u5165\u7814\u7a76\u7684\u53c2\u8003\u6587\u732e\u5217\u8868\uff0c\u4ee5\u786e\u4fdd\u5168\u9762\u8986\u76d6\u76f8\u5173\u6587\u732e\u3002<\/p>\n<p><strong>\u7eb3\u5165\u4e0e\u6392\u9664\u6807\u51c6\uff1a<\/strong><\/p>\n<p>\u7eb3\u5165\u6807\u51c6\uff1a\uff081\uff09\u7814\u7a76\u8bbe\u8ba1\u4e3a\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff1b\uff082\uff09\u7814\u7a76\u5bf9\u8c61\u4e3a\u819d\u9aa8\u5173\u8282\u708e\u60a3\u8005\uff1b\uff083\uff09\u5e72\u9884\u63aa\u65bd\u4e3a\u5355\u6b21\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff1b\uff084\uff09\u5bf9\u7167\u7ec4\u4e3a\u5b89\u6170\u5242\u3001\u751f\u7406\u76d0\u6c34\u6216\u4f20\u7edf\u6cbb\u7597\uff1b\uff085\uff09\u62a5\u544a\u4e86\u57fa\u7ebf\u548c12\u4e2a\u6708\u968f\u8bbf\u65f6\u7684WOMAC\u8bc4\u5206\u3002<\/p>\n<p>\u6392\u9664\u6807\u51c6\uff1a\uff081\uff09\u975e\u968f\u673a\u7814\u7a76\u8bbe\u8ba1\uff1b\uff082\uff09\u7f3a\u4e4f\u60a3\u8005\u76f2\u6cd5\uff1b\uff083\uff09\u672a\u4f7f\u7528\u5206\u79bb\u7eaf\u5316\u7684MSC\uff1b\uff084\uff09MSC\u5242\u91cf\u672a\u660e\u786e\uff1b\uff085\uff09MSC\u4e0e\u5176\u4ed6\u5e72\u9884\u63aa\u65bd\u8054\u5408\u4f7f\u7528\uff1b\uff086\uff09\u672a\u62a5\u544a12\u4e2a\u6708\u65f6\u7684WOMAC\u603b\u8bc4\u5206\u3002<\/p>\n<p><strong>\u6570\u636e\u63d0\u53d6\u4e0e\u8d28\u91cf\u8bc4\u4f30\uff1a<\/strong>\u4e24\u540d\u7814\u7a76\u8005\u72ec\u7acb\u8fdb\u884c\u6570\u636e\u63d0\u53d6\uff0c\u5305\u62ec\u7814\u7a76\u7279\u5f81\u3001\u60a3\u8005\u4eba\u53e3\u5b66\u8d44\u6599\u3001\u5e72\u9884\u7ec6\u8282\u3001\u7ed3\u5c40\u6307\u6807\u7b49\u3002\u7814\u7a76\u8d28\u91cf\u91c7\u7528Cochrane\u504f\u501a\u98ce\u9669\u8bc4\u4f30\u5de5\u5177\u8fdb\u884c\u8bc4\u4ef7\uff0c\u91cd\u70b9\u5173\u6ce8\u968f\u673a\u5e8f\u5217\u751f\u6210\u3001\u5206\u914d\u9690\u85cf\u3001\u76f2\u6cd5\u5b9e\u65bd\u3001\u6570\u636e\u5b8c\u6574\u6027\u3001\u9009\u62e9\u6027\u62a5\u544a\u7b49\u65b9\u9762\u3002\u610f\u89c1\u4e0d\u4e00\u81f4\u65f6\u901a\u8fc7\u8ba8\u8bba\u6216\u7b2c\u4e09\u4f4d\u7814\u7a76\u8005\u88c1\u5b9a\u89e3\u51b3\u3002<\/p>\n<p><strong>\u7edf\u8ba1\u5206\u6790\uff1a<\/strong>\u91c7\u7528RevMan 5.4\u8f6f\u4ef6\u8fdb\u884c\u835f\u8403\u5206\u6790\u3002\u4e3b\u8981\u7ed3\u5c40\u6307\u6807\u4e3a12\u4e2a\u6708\u65f6WOMAC\u8bc4\u5206\u7684\u6807\u51c6\u5316\u5747\u6570\u5dee\uff08SMD\uff09\u53ca95%\u7f6e\u4fe1\u533a\u95f4\uff08CI\uff09\u3002\u9274\u4e8e\u7814\u7a76\u95f4\u7684\u4e34\u5e8a\u5f02\u8d28\u6027\uff0c\u91c7\u7528\u968f\u673a\u6548\u5e94\u6a21\u578b\u5408\u5e76\u6548\u5e94\u91cf\u3002\u901a\u8fc7I\u00b2\u7edf\u8ba1\u91cf\u548cQ\u68c0\u9a8c\u8bc4\u4f30\u5f02\u8d28\u6027\uff0cI\u00b2&gt;50%\u6216p&lt;0.1\u88ab\u8ba4\u4e3a\u5b58\u5728\u663e\u8457\u5f02\u8d28\u6027\u3002\u8fdb\u884c\u4e9a\u7ec4\u5206\u6790\u548cmeta\u56de\u5f52\u5206\u6790\u4ee5\u8bc4\u4f30MSC\u5242\u91cf\uff08\u22642500\u4e07\u7ec6\u80devs.&gt;2500\u4e07\u7ec6\u80de\uff09\u5bf9\u6cbb\u7597\u7ed3\u679c\u7684\u5f71\u54cd\u3002\u901a\u8fc7\u6f0f\u6597\u56fe\u548cEgger\u68c0\u9a8c\u8bc4\u4f30\u53d1\u8868\u504f\u501a\u3002\u8bc1\u636e\u8d28\u91cf\u91c7\u7528GRADE\u6846\u67b6\u8fdb\u884c\u8bc4\u7ea7\u3002<\/p>\n<h2 data-spm-anchor-id=\"5176.28103460.0.i53.39367551ItdekH\"><span class=\"ez-toc-section\" id=\"%E7%BB%93%E6%9E%9C\"><\/span>\u7ed3\u679c<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>\u6587\u732e\u7b5b\u9009\u6d41\u7a0b\uff1a<\/strong>\u7cfb\u7edf\u6027\u6587\u732e\u68c0\u7d22\u5171\u83b7\u5f9759\u6761\u552f\u4e00\u8bb0\u5f55\uff0c\u53bb\u966426\u6761\u91cd\u590d\u8bb0\u5f55\u540e\uff0c59\u6761\u8bb0\u5f55\u5747\u6839\u636e\u6807\u9898\u548c\u6458\u8981\u8fdb\u884c\u7b5b\u9009\uff0c30\u7bc7\u6587\u7ae0\u8fdb\u5165\u5168\u6587\u5ba1\u9605\u9636\u6bb5\u3002\u7ecf\u8fc7\u4e25\u683c\u8bc4\u4f30\uff0c24\u7bc7\u6587\u7ae0\u56e0\u4e0d\u7b26\u5408\u7eb3\u5165\u6807\u51c6\u88ab\u6392\u9664\uff0c\u5305\u62ec\uff1a\u975e\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff08n=5\uff09\u3001\u7f3a\u4e4f\u60a3\u8005\u76f2\u6cd5\u8bbe\u8ba1\uff08n=7\uff09\u3001\u672a\u4f7f\u7528\u5206\u79bb\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08n=3\uff09\u3001MSC\u5242\u91cf\u672a\u660e\u786e\uff08n=3\uff09\u3001\u672a\u62a5\u544a12\u4e2a\u6708\u65f6WOMAC\u603b\u8bc4\u5206\uff08n=4\uff09\u6216\u5c06MSC\u4e0e\u5176\u4ed6\u5e72\u9884\u63aa\u65bd\u8054\u5408\u4f7f\u7528\uff08n=2\uff09\u3002\u6700\u7ec8\uff0c6\u9879\u7814\u7a76\u7b26\u5408\u6240\u6709\u7eb3\u5165\u6807\u51c6\uff0c\u88ab\u7eb3\u5165\u7cfb\u7edf\u8bc4\u4ef7\u548c\u835f\u8403\u5206\u6790\uff08\u56fe1\uff09\u3002<\/p>\n<p><strong>\u7eb3\u5165\u7814\u7a76\u7279\u5f81\uff1a<\/strong>\u8fd96\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u5206\u5e03\u5728\u4f0a\u6717\u3001\u897f\u73ed\u7259\u3001\u97e9\u56fd\u3001\u5370\u5ea6\u3001\u53f0\u6e7e\u3001\u667a\u5229\u548c\u54e5\u4f26\u6bd4\u4e9a\u7b49\u5730\u533a\uff0c\u4f53\u73b0\u4e86\u7814\u7a76\u7684\u5730\u7406\u591a\u6837\u6027\u3002\u6240\u6709\u7814\u7a76\u5747\u91c7\u7528\u5355\u6b21\u5173\u8282\u5185\u6ce8\u5c04\u5f02\u4f53\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u65b9\u6848\uff0c\u7ec6\u80de\u6765\u6e90\u591a\u6837\uff0c\u5305\u62ec\u8102\u80aa\u7ec4\u7ec7\uff08n=3\uff09\u3001\u9aa8\u9ad3\uff08n=2\uff09\u548c\u8110\u5e26\uff08n=1\uff09\u3002\u7ed9\u836f\u5242\u91cf\u8303\u56f4\u4e3a16\u00d710\u2076\u81f3100\u00d710\u2076\u4e2a\u7ec6\u80de\uff0c\u968f\u8bbf\u65f6\u95f4\u8bbe\u5b9a\u572848\u5468\u81f312\u4e2a\u6708\u4e4b\u95f4\u3002\u9664WOMAC\u8bc4\u5206\u5916\uff0c\u90e8\u5206\u7814\u7a76\u8fd8\u62a5\u544a\u4e86VAS\u75bc\u75db\u8bc4\u5206\u3001KOOS\u529f\u80fd\u8bc4\u5206\u3001SF-36\u751f\u6d3b\u8d28\u91cf\u8bc4\u5206\u4ee5\u53caMRI\u6216\u751f\u7269\u6807\u5fd7\u7269\u7b49\u5f71\u50cf\u5b66\u4e0e\u5b9e\u9a8c\u5ba4\u7ed3\u679c\u3002<\/p>\n<table class=\"data last-table\">\n<thead class=\"c-article-table-head\">\n<tr>\n<th class=\"u-text-left\"><span dir=\"auto\">\u7814\u7a76\uff08\u4f5c\u8005\uff0c\u5e74\u4efd\uff09<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u56fd\u5bb6\u53ca\u5730\u533a<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u6837\u672c\u91cf<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">MSC\u6765\u6e90\u4e0e\u5bf9\u7167\u7ec4<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u5242\u91cf\uff08\u7ec6\u80de\uff09<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u968f\u8bbf\u6301\u7eed\u65f6\u95f4<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u7ed3\u679c\u8861\u91cf<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d146623553e906\" title=\"Sadri B \u7b49\u3002\u6ce8\u5c04\u540c\u79cd\u5f02\u4f53\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u540e\u819d\u9aa8\u5173\u8282\u708e\u8f6f\u9aa8\u518d\u751f\u548c\u708e\u75c7\u8c03\u8282\uff1a\u4e00\u9879 II \u671f\u3001\u4e09\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u968f\u673a\u8bd5\u9a8c\u3002\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u30022023;14:162\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR19\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e19\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">19<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u4f0a\u6717<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">40\uff0820 MSC\uff09<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">AD\uff08\u540c\u79cd\u5f02\u4f53\uff09\u4e0e\u751f\u7406\u76d0\u6c34<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">100\u2009<\/span><\/span><\/span><span id=\"MathJax-Element-1-Frame\" class=\"MathJax_SVG\" tabindex=\"0\" role=\"presentation\" data-mathml=\"&lt;math xmlns=&quot;http:\/\/www.w3.org\/1998\/Math\/MathML&quot;&gt;&lt;mo&gt;&amp;#x00D7;&lt;\/mo&gt;&lt;\/math&gt;\"><\/span><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u200910\u00a0 <\/span><\/span><\/span><sup><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6<\/span><\/span><\/span><\/sup><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">12\u4e2a\u6708<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">WOMAC\u3001VAS\u3001KOOS\u3001SF-36\u3001MRI\u3001\u751f\u7269\u6807\u5fd7\u7269<\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d146623553e969\" title=\"Vega A \u7b49\u3002\u5f02\u4f53\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u4e00\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u3002\u79fb\u690d\u30022015\uff1b99\uff1a1681\u201390\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR20\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e20\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">20<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u897f\u73ed\u7259<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">30 (15 MSC)<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">BM\uff08\u540c\u79cd\u5f02\u4f53\uff09\u4e0eHA<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">40\u2009<\/span><\/span><\/span><span id=\"MathJax-Element-2-Frame\" class=\"MathJax_SVG\" tabindex=\"0\" role=\"presentation\" data-mathml=\"&lt;math xmlns=&quot;http:\/\/www.w3.org\/1998\/Math\/MathML&quot;&gt;&lt;mo&gt;&amp;#x00D7;&lt;\/mo&gt;&lt;\/math&gt;\"><\/span><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u200910\u00a0 <\/span><\/span><\/span><sup><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6<\/span><\/span><\/span><\/sup><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">12\u4e2a\u6708<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">WOMAC\u8bc4\u5206\u3001VAS\u8bc4\u5206\u3001Lequesne\u6307\u6570\u3001SF-12\u91cf\u8868\u3001MRI\uff08T2\u6620\u5c04\uff09<\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d146623553e1032\" title=\"Lee BW\u3001Lee JJ\u3001Jung JY\u3001Ju JH\u3002\u5173\u8282\u5185\u6ce8\u5c04\u4eba\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5bf9\u7167\u8bd5\u9a8c\u3002\u7ec6\u80de\u79fb\u690d\u30022025\uff1b34\uff1a09636897241303275\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR21\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e21\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">21<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u97e9\u56fd<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">24 (12 MSC)<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">BM\uff08\u540c\u79cd\u5f02\u4f53\uff09\u4e0e\u751f\u7406\u76d0\u6c34<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">100\u00a0<\/span><\/span><\/span><span id=\"MathJax-Element-3-Frame\" class=\"MathJax_SVG\" tabindex=\"0\" role=\"presentation\" data-mathml=\"&lt;math xmlns=&quot;http:\/\/www.w3.org\/1998\/Math\/MathML&quot;&gt;&lt;mo&gt;&amp;#x00D7;&lt;\/mo&gt;&lt;\/math&gt;\"><\/span><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">10\u00a0 <\/span><\/span><\/span><sup><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6<\/span><\/span><\/span><\/sup><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">12\u4e2a\u6708<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">WOMAC\u3001VAS\u3001KOOS\u3001MRI\uff08T2 mapping\uff09\u3001\u751f\u7269\u6807\u5fd7\u7269<\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d146623553e1095\" title=\"Gupta PK \u7b49\u3002Stempeucel \u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\uff1a\u4e00\u9879 3 \u671f\u968f\u673a\u3001\u53cc\u76f2\u3001\u591a\u4e2d\u5fc3\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7814\u7a76\u3002Am J Sports Med. 2023;51:2254\u201366\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR22\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e22\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">22<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u5370\u5ea6<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">146 (73 MSC)<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">BM\uff08\u540c\u79cd\u5f02\u4f53\uff09\u4e0eHA<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">25\u00a0<\/span><\/span><\/span><span id=\"MathJax-Element-4-Frame\" class=\"MathJax_SVG\" tabindex=\"0\" role=\"presentation\" data-mathml=\"&lt;math xmlns=&quot;http:\/\/www.w3.org\/1998\/Math\/MathML&quot;&gt;&lt;mo&gt;&amp;#x00D7;&lt;\/mo&gt;&lt;\/math&gt;\"><\/span><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">10\u00a0 <\/span><\/span><\/span><sup><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6<\/span><\/span><\/span><\/sup><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">12\u4e2a\u6708<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">WOMAC\u3001VAS\u3001MRI\uff08T2 mapping\uff09\u3001CTX-II\u3001IL-10<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d146623553e1158\" title=\"Chen CF \u7b49\u3002\u5173\u8282\u5185\u6ce8\u5c04\u5f02\u4f53\u8102\u80aa\u5e72\u7ec6\u80de (ADSC) ELIXCYTE\u00ae \u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u4e00\u9879 I\/II \u671f\u968f\u673a\u3001\u6d3b\u6027\u5bf9\u7167\u3001\u5355\u76f2\u3001\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\u3002\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u30022021;12:562\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR23\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e23\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">23<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u53f0\u6e7e<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">57\uff0849 \u4e2a MSC \u81c2\uff09<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">AD\uff08\u540c\u79cd\u5f02\u4f53\uff09\u4e0eHA<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">16\u300132\u300164\u00a0<\/span><\/span><\/span><span id=\"MathJax-Element-5-Frame\" class=\"MathJax_SVG\" tabindex=\"0\" role=\"presentation\" data-mathml=\"&lt;math xmlns=&quot;http:\/\/www.w3.org\/1998\/Math\/MathML&quot;&gt;&lt;mo&gt;&amp;#x00D7;&lt;\/mo&gt;&lt;\/math&gt;\"><\/span><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">10\u00a0 <\/span><\/span><\/span><sup><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6<\/span><\/span><\/span><\/sup><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">48\u5468<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">WOMAC\u3001VAS\u3001KSCRS<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d146623553e1222\" title=\"Matas J \u7b49\u3002\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de (MSC) \u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u5728\u5bf9\u7167\u968f\u673a I\/II \u671f\u8bd5\u9a8c\u4e2d\uff0c\u91cd\u590d MSC \u7ed9\u836f\u4f18\u4e8e\u5355\u6b21 MSC \u7ed9\u836f\u548c\u900f\u660e\u8d28\u9178\u3002\u5e72\u7ec6\u80de\u8f6c\u5316\u533b\u5b66\u30022019;8:215\u201324\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR24\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e24\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">24<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u667a\u5229<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">27\uff089 \u4f8b MSC \u5355\u5242\u91cf\u7ec4\uff0c8 \u4f8b\u5bf9\u7167\u7ec4\uff09<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">UC\uff08\u540c\u79cd\u5f02\u4f53\uff09\u4e0e\u5b89\u6170\u5242<\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">20\u00a0<\/span><\/span><\/span><span id=\"MathJax-Element-6-Frame\" class=\"MathJax_SVG\" tabindex=\"0\" role=\"presentation\" data-mathml=\"&lt;math xmlns=&quot;http:\/\/www.w3.org\/1998\/Math\/MathML&quot;&gt;&lt;mo&gt;&amp;#x00D7;&lt;\/mo&gt;&lt;\/math&gt;\"><\/span><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">10\u00a0 <\/span><\/span><\/span><sup><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6<\/span><\/span><\/span><\/sup><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">12\u4e2a\u6708<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">WOMAC\u3001VAS\u3001SF-36\u3001OMERACT-OARSI\u3001MRI\uff08WORMS\uff09<\/span><\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b id=\"Tab1\" data-test=\"table-caption\"><span dir=\"auto\">\u88681 \u7eb3\u5165\u7814\u7a76\u7684\u6982\u8981<\/span><\/b><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%B8%BB%E8%A6%81%E7%BB%93%E5%B1%80%EF%BC%9A12%E4%B8%AA%E6%9C%88WOMAC%E8%AF%84%E5%88%86\"><\/span>\u4e3b\u8981\u7ed3\u5c40\uff1a12\u4e2a\u6708WOMAC\u8bc4\u5206<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span dir=\"auto\">\u672c\u6b21\u835f\u8403\u5206\u6790\u5171\u7eb3\u51656\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff0c\u6d89\u53ca8\u4e2a\u72ec\u7acb\u7684MSC\u6cbb\u7597\u7ec4\u3002Chen\u7b49[<\/span><a id=\"ref-link-section-d146623553e1284\" title=\"Chen CF \u7b49\u3002\u5173\u8282\u5185\u6ce8\u5c04\u5f02\u4f53\u8102\u80aa\u5e72\u7ec6\u80de(ADSC) ELIXCYTE\u00ae \u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u4e00\u9879I\/II \u671f\u968f\u673a\u3001\u6d3b\u6027\u5bf9\u7167\u3001\u5355\u76f2\u3001\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\u3002\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u3002 2021;12:562\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR23\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e23\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\">23<\/span><\/a><span dir=\"auto\">]\u7684\u7814\u7a76\u7eb3\u5165\u4e863\u4e2a\u5e73\u884c\u7ec4\uff0c\u5206\u522b\u91c7\u7528\u4e0d\u540c\u7684MSC\u5242\u91cf\uff081600\u4e07\u30013200\u4e07\u548c6400\u4e07\u4e2a\u7ec6\u80de\uff09\uff0c\u6bcf\u4e2a\u7ec4\u5747\u4e0e\u5bf9\u7167\u7ec4\u8fdb\u884c\u5355\u72ec\u6bd4\u8f83\u3002\u5728\u8fd9\u4e9b\u6cbb\u7597\u7ec4\u4e2d\uff0c12\u4e2a\u6708\u968f\u8bbf\u65f6WOMAC\u8bc4\u5206\u7684\u6807\u51c6\u5316\u5747\u6570\u5dee\uff08SMD\uff09\u8303\u56f4\u4e3a-0.39\u81f3-2.99\u3002Chen\u7b49[<\/span><a id=\"ref-link-section-d146623553e1287\" title=\"Chen CF \u7b49\u3002\u5173\u8282\u5185\u6ce8\u5c04\u5f02\u4f53\u8102\u80aa\u5e72\u7ec6\u80de(ADSC) ELIXCYTE\u00ae \u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u4e00\u9879I\/II \u671f\u968f\u673a\u3001\u6d3b\u6027\u5bf9\u7167\u3001\u5355\u76f2\u3001\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\u3002\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u3002 2021;12:562\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR23\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e23\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\">23<\/span><\/a><span dir=\"auto\">]\u7684\u7814\u7a76\u4e2d\uff0c3200\u4e07\u4e2a\u7ec6\u80de\u7ec4\u7684\u7597\u6548\u6700\u4e3a\u663e\u8457\uff08SMD = -2.985\uff0c95% CI\uff1a-4.578\u81f3-1.392\uff09\uff0c\u800cLee\u7b49\uff082019\uff09\u7684\u7814\u7a76\u5219\u62a5\u9053\u4e86\u7597\u6548\u6700\u5f31\u4e14\u65e0\u7edf\u8ba1\u5b66\u610f\u4e49\u7684\u7597\u6548\uff08SMD = -0.391\uff0c95% CI\uff1a-1.217\u81f30.435\uff09\uff08\u88682<\/span><span dir=\"auto\">\uff09\u3002\u516b\u9879\u6bd4\u8f83\u4e2d\u6709\u4e03\u9879\u663e\u793a WOMAC \u8bc4\u5206\u6709\u7edf\u8ba1\u5b66\u610f\u4e49\u4e0a\u7684\u663e\u8457\u6539\u5584\uff0c\u652f\u6301\u5173\u8282\u5185 MSC \u6ce8\u5c04\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\u7684\u7597\u6548\uff08\u88683<\/span><span dir=\"auto\">\uff09\u3002<\/span><\/p>\n<table class=\"data last-table\">\n<thead class=\"c-article-table-head\">\n<tr>\n<th class=\"u-text-left\"><span dir=\"auto\">\u5e8f\u53f7<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u968f\u673a\u5316<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u504f\u5dee<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u7f3a\u5931\u6570\u636e<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u7ed3\u679c\u6d4b\u91cf<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u62a5\u544a<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u603b\u4f53 RoB<\/span><\/th>\n<th class=\"u-text-left\"><span dir=\"auto\">\u539f\u56e0\u201c\u5b58\u5728\u4e00\u4e9b\u62c5\u5fe7\u201d<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d148742134e1382\" title=\"Vega A \u7b49\u3002\u5f02\u4f53\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u4e00\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u3002\u79fb\u690d\u3002 2015\uff1b99\uff1a1681\u201390\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR20\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e20\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">20<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u4e00\u4e9b\u62c5\u5fe7<\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw78\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figa_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u4f4e\u98ce\u9669<\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figb_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figc_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figd_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Fige_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e00\u4e9b\u62c5\u5fe7<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw78\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figf_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u5e8f\u5217\u751f\u6210\u548c\u9690\u85cf\u8fc7\u7a0b\u672a\u4f5c\u63cf\u8ff0\u3002<\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d148742134e1472\" title=\"Sadri B \u7b49\u3002\u6ce8\u5c04\u540c\u79cd\u5f02\u4f53\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u540e\u819d\u9aa8\u5173\u8282\u708e\u8f6f\u9aa8\u518d\u751f\u548c\u708e\u75c7\u8c03\u8282\uff1a\u4e00\u9879II \u671f\u3001\u4e09\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u968f\u673a\u8bd5\u9a8c\u3002\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u3002 2023;14:162\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR19\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e19\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">19<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figg_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figh_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figi_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figj_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figk_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figl_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u2014<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d148742134e1562\" title=\"Matas J \u7b49\u3002\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de(MSC) \u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u5728\u5bf9\u7167\u968f\u673aI\/II \u671f\u8bd5\u9a8c\u4e2d\uff0c\u91cd\u590dMSC \u7ed9\u836f\u4f18\u4e8e\u5355\u6b21MSC \u7ed9\u836f\u548c\u900f\u660e\u8d28\u9178\u3002\u5e72\u7ec6\u80de\u8f6c\u5316\u533b\u5b66\u3002 2019;8:215\u201324\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR24\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e24\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">24<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e00\u4e9b\u62c5\u5fe7<\/span><\/span><\/span><\/p>\n<p><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">s<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw78\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figm_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Fign_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figo_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figp_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figq_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e00\u4e9b\u62c5\u5fe7<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw78\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figr_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u672a\u62a5\u544a\u968f\u673a\u5e8f\u5217\u751f\u6210\u8fc7\u7a0b<\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d148742134e1654\" title=\"Lee BW\u3001Lee JJ\u3001Jung JY\u3001Ju JH\u3002\u5173\u8282\u5185\u6ce8\u5c04\u4eba\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5bf9\u7167\u8bd5\u9a8c\u3002\u7ec6\u80de\u79fb\u690d\u3002 2025\uff1b34\uff1a09636897241303275\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR21\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e21\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">21<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figs_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figt_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figu_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u4f4e\u98ce\u9669\u00a0<\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figv_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figw_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figx_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u2014<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d148742134e1742\" title=\"Gupta PK \u7b49\u3002 Stempeucel \u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\uff1a\u4e00\u98793 \u671f\u968f\u673a\u3001\u53cc\u76f2\u3001\u591a\u4e2d\u5fc3\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7814\u7a76\u3002 Am J Sports Med. 2023;51:2254\u201366\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR22\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e22\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">22<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figy_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figz_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figaa_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figab_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figac_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figad_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u2014<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[\u00a0 <\/span><\/span><\/span><a id=\"ref-link-section-d148742134e1833\" title=\"Chen CF \u7b49\u3002\u5173\u8282\u5185\u6ce8\u5c04\u5f02\u4f53\u8102\u80aa\u5e72\u7ec6\u80de(ADSC) ELIXCYTE\u00ae \u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\uff1a\u4e00\u9879I\/II \u671f\u968f\u673a\u3001\u6d3b\u6027\u5bf9\u7167\u3001\u5355\u76f2\u3001\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\u3002\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u3002 2021;12:562\u3002\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s13018-025-06190-4#ref-CR23\" data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"\u53c2\u8003\u6587\u732e23\" rel=\"nofollow noopener\" target=\"_blank\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">23<\/span><\/span><\/span><\/a><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0]<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figae_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e00\u4e9b\u62c5\u5fe7<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw78\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figaf_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figag_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figah_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u98ce\u9669<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw68\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figai_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e00\u4e9b\u62c5\u5fe7<\/span><\/span><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw78\/springer-static\/image\/art%3A10.1186%2Fs13018-025-06190-4\/MediaObjects\/13018_2025_6190_Figaj_HTML.png\" alt=\"\" title=\"\"><\/td>\n<td class=\"u-text-left\"><span dir=\"auto\">\u8be5\u7814\u7a76\u91c7\u7528\u5355\u76f2\uff08\u53c2\u4e0e\u8005\u76f2\u6cd5\uff09\u8bbe\u8ba1\u3002<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b id=\"Tab2\" data-test=\"table-caption\"><span dir=\"auto\">\u88682 \u7eb3\u5165\u7814\u7a76\u7684RoB 2\u8bc4\u5206<\/span><\/b><\/p>\n<table class=\"data last-table\" style=\"width: 40.559%; height: 576px;\">\n<thead class=\"c-article-table-head\">\n<tr style=\"height: 80px;\">\n<th class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5e8f\u53f7<\/span><\/span><\/span><\/th>\n<th class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\">\u8868\u9762\u8d34\u88c5\u836f<\/span><\/th>\n<th class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">SE SMD<\/span><\/span><\/span><\/th>\n<th class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\">95% \u7f6e\u4fe1\u533a\u95f4\u4e0b\u9650<\/span><\/th>\n<th class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\">95% \u7f6e\u4fe1\u533a\u95f4\u4e0a\u9650<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"height: 56px;\">\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\">\u9648 2021 (16 M)<\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22121.584<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">0.705<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22122.967<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22120.202<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr style=\"height: 80px;\">\n<td class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\">\u9648 2021 (32 M)<\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22122.985<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">0.813<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22124.578<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22121.392<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr style=\"height: 80px;\">\n<td class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\">\u9648 2021 (64 M)<\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22121.954<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">0.741<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22123.407<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 80px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22120.501<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr style=\"height: 56px;\">\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\">\u53e4\u666e\u5854 2023<\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22121.266<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">0.181<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22121.621<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22120.910<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr style=\"height: 56px;\">\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\">\u674e 2019<\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22120.391<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">0.421<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22121.217<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">0.435<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr style=\"height: 56px;\">\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\">2018\u5e74\u9a6c\u5854\u65af<\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22120.701<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">0.501<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22121.682<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">0.280<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr style=\"height: 56px;\">\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Sadri 2023<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22121.657<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">0.386<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22122.414<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22120.899<\/span><\/span><\/span><\/td>\n<\/tr>\n<tr style=\"height: 56px;\">\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\">\u7ef4\u52a0 2015<\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22121.434<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">0.409<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22122.236<\/span><\/span><\/span><\/td>\n<td class=\"u-text-left\" style=\"height: 56px;\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u22120.631<\/span><\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p data-spm-anchor-id=\"5176.28103460.0.i56.39367551ItdekH\"><span dir=\"auto\">\u88683 \u7eb3\u5165\u7814\u7a76\u4e2dWOMAC\u603b\u8bc4\u5206\u572812\u4e2a\u6708\u65f6\u7684\u6807\u51c6\u5316\u5747\u6570\u5dee\uff08SMD\uff09\u548c95%\u7f6e\u4fe1\u533a\u95f4<\/span><\/p>\n<h2 data-spm-anchor-id=\"5176.28103460.0.i56.39367551ItdekH\"><span class=\"ez-toc-section\" id=\"%E6%A3%AE%E6%9E%97%E5%9B%BE\"><\/span>\u68ee\u6797\u56fe<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-spm-anchor-id=\"5176.28103460.0.i56.39367551ItdekH\"><span dir=\"auto\">\u5bf9\u516b\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u7684\u835f\u8403\u5206\u6790\u663e\u793a\uff0c\u63a5\u53d7\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u6cbb\u7597\u7684\u60a3\u8005\u572812\u4e2a\u6708\u968f\u8bbf\u65f6WOMAC\u8bc4\u5206\u8f83\u5bf9\u7167\u7ec4\u6709\u663e\u8457\u6539\u5584\uff08SMD = -1.35\uff0c95% CI\uff1a-1.97\u81f3-0.74\uff0c<\/span><i><span dir=\"auto\">p = 0.002\uff09\uff0c\u5982\u56fe2<\/span><\/i><span dir=\"auto\">\u6240\u793a\u00a0\u3002\u5404\u7814\u7a76\u95f4\u7684\u5f02\u8d28\u6027\u4e3a\u4e2d\u7b49\uff08Q(6) = 11.95\uff0c<\/span><i><span dir=\"auto\">p<\/span><\/i><span dir=\"auto\">\u00a0\u2009= 0.063\uff1bI\u00b2 = 49.8%\uff1b\u03c4\u00b2 = 0.47\uff09\u3002\u7ed3\u679c\u8868\u660e\uff0cMSC\u7597\u6cd5\u5bf9\u819d\u9aa8\u5173\u8282\u708e\u5177\u6709\u4e2d\u7b49\u81f3\u8f83\u5927\u7684\u7597\u6548\u3002<\/span><\/p>\n<div id=\"attachment_20482\" style=\"width: 1958px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20482\" class=\"wp-image-20482 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-14_153444_638.png\" alt=\"\" width=\"1948\" height=\"601\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-14_153444_638.png 1948w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-14_153444_638-300x93.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-14_153444_638-1024x316.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-14_153444_638-768x237.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-14_153444_638-1536x474.png 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/11\/\u5fae\u4fe1\u56fe\u7247_2025-11-14_153444_638-18x6.png 18w\" sizes=\"(max-width: 1948px) 100vw, 1948px\" \/><p id=\"caption-attachment-20482\" class=\"wp-caption-text\">\u56fe2\uff1a\u7eb3\u5165\u7814\u7a76\u7684\u68ee\u6797\u56fe<\/p><\/div>\n<h2 data-spm-anchor-id=\"5176.28103460.0.i56.39367551ItdekH\"><span class=\"ez-toc-section\" id=\"%E5%89%82%E9%87%8F-%E6%95%88%E5%BA%94%E5%85%B3%E7%B3%BB%E5%88%86%E6%9E%90\"><\/span>\u5242\u91cf-\u6548\u5e94\u5173\u7cfb\u5206\u6790<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-spm-anchor-id=\"5176.28103460.0.i57.39367551ItdekH\">\u835f\u8403\u56de\u5f52\u5206\u6790\u8868\u660e\uff0c\u6ce8\u5c04\u5242\u91cf\u22642500\u4e07\u4e2aMSC\u53ef\u663e\u8457\u6539\u558412\u4e2a\u6708\u65f6\u7684WOMAC\u8bc4\u5206\uff08SMD = -1.165\uff0c95% CI\uff1a-2.110\u81f3-0.220\uff0cp = 0.023\uff09\u3002\u76f8\u53cd\uff0c\u5242\u91cf&gt;2500\u4e07\u4e2a\u7ec6\u80de\u4e0e\u8f83\u4f4e\u5242\u91cf\u76f8\u6bd4\uff0c\u7597\u6548\u65e0\u7edf\u8ba1\u5b66\u663e\u8457\u5dee\u5f02\uff08\u03b2 = -0.310\uff0c95% CI\uff1a-1.552\u81f30.932\uff0cp = 0.564\uff09\u3002\u8fd9\u4e00\u7ed3\u679c\u8868\u660e\uff0c\u4f4e\u5242\u91cfMSC\uff08\u22642500\u4e07\u4e2a\u7ec6\u80de\uff09\u5373\u53ef\u5e26\u6765\u663e\u8457\u4e34\u5e8a\u83b7\u76ca\uff0c\u589e\u52a0\u5242\u91cf\u5e76\u672a\u5e26\u6765\u989d\u5916\u7684\u7597\u6548\u4f18\u52bf\u3002<\/p>\n<div id=\"Sec15-content\" class=\"c-article-section__content\">\n<h2 data-spm-anchor-id=\"5176.28103460.0.i58.39367551ItdekH\"><span class=\"ez-toc-section\" id=\"%E8%AE%A8%E8%AE%BA\"><\/span>\u8ba8\u8bba<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-spm-anchor-id=\"5176.28103460.0.i60.39367551ItdekH\">\u672c\u835f\u8403\u5206\u6790\u660e\u786e\u8bc1\u5b9e\u4e86\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\u7684\u4e34\u5e8a\u4ef7\u503c\uff0c\u7279\u522b\u662f\u572812\u4e2a\u6708\u65f6\u70b9\u7684\u6301\u7eed\u7597\u6548\u3002\u901a\u8fc7\u5bf96\u9879\u9ad8\u8d28\u91cf\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u7684\u7efc\u5408\u5206\u6790\uff0c\u6211\u4eec\u53d1\u73b0MSC\u6cbb\u7597\u53ef\u663e\u8457\u6539\u5584\u60a3\u8005\u7684WOMAC\u8bc4\u5206\uff08SMD = 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class=\"ez-toc-section\" id=\"%E7%BB%93%E8%AE%BA\"><\/span>reach a verdict<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p data-spm-anchor-id=\"5176.28103460.0.i59.39367551ItdekH\">\u672c\u835f\u8403\u5206\u6790\u63d0\u4f9b\u6709\u529b\u8bc1\u636e\uff0c\u8bc1\u660e\u5173\u8282\u5185\u6ce8\u5c04\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u662f\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\u7684\u6709\u6548\u7b56\u7565\uff0c\u4e14\u4f4e\u5242\u91cf\u65b9\u6848\uff08\u22642500\u4e07\u4e2a\u7ec6\u80de\uff09\u5373\u53ef\u5b9e\u73b0\u663e\u8457\u4e34\u5e8a\u83b7\u76ca\u3002\u8fd9\u4e00&#8221;\u5c11\u5373\u662f\u591a&#8221;\u7684\u53d1\u73b0\u6311\u6218\u4e86\u4f20\u7edf\u9ad8\u5242\u91cf\u601d\u7ef4\uff0c\u4e3a\u4e34\u5e8a\u5b9e\u8df5\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u5242\u91cf\u4f18\u5316\u6307\u5bfc\u3002\u4f4e\u5242\u91cfMSC\u6cbb\u7597\u4e0d\u4ec5\u53ef\u4fdd\u6301\u7597\u6548\uff0c\u8fd8\u80fd\u63d0\u9ad8\u6210\u672c\u6548\u76ca\uff0c\u6269\u5927\u6cbb\u7597\u53ef\u53ca\u6027\uff0c\u5e76\u53ef\u80fd\u51cf\u5c11\u6f5c\u5728\u98ce\u9669\u3002\u672a\u6765\u7814\u7a76\u5e94\u805a\u7126\u4e8e\u786e\u5b9a\u7cbe\u786e\u7684\u6700\u4f73\u5242\u91cf\u7a97\u53e3\uff0c\u6807\u51c6\u5316\u6cbb\u7597\u65b9\u6848\uff0c\u5e76\u901a\u8fc7\u957f\u671f\u968f\u8bbf\u9a8c\u8bc1\u7597\u6548\u6301\u4e45\u6027\uff0c\u6700\u7ec8\u63a8\u52a8MSC\u7597\u6cd5\u4ece\u5b9e\u9a8c\u7814\u7a76\u5411\u5e38\u89c4\u4e34\u5e8a\u5e94\u7528\u7684\u8f6c\u5316\u3002\u5728\u819d\u9aa8\u5173\u8282\u708e\u6cbb\u7597\u65e5\u76ca\u5f3a\u8c03\u4e2a\u4f53\u5316\u548c\u7cbe\u51c6\u5316\u7684\u65f6\u4ee3\uff0c\u8fd9\u4e00\u5242\u91cf\u4f18\u5316\u7b56\u7565\u4e3aMSC\u6cbb\u7597\u7684\u666e\u53ca\u548c\u6807\u51c6\u5316\u5960\u5b9a\u4e86\u57fa\u7840\u3002<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u819d\u9aa8\u5173\u8282\u708e\uff08OA\uff09\u662f\u4e00\u79cd\u9ad8\u53d1\u7684\u9000\u884c\u6027\u5173\u8282\u75be\u75c5\uff0c\u4e5f\u662f\u5168\u7403\u75bc\u75db\u548c\u6b8b\u75be\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\uff0c\u5f71\u54cd\u7740\u7ea66.54\u4ebf40\u5c81\u53ca\u4ee5\u4e0a [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[61],"tags":[189,178,207],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20479"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/comments?post=20479"}],"version-history":[{"count":1,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20479\/revisions"}],"predecessor-version":[{"id":20483,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20479\/revisions\/20483"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media?parent=20479"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/categories?post=20479"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/tags?post=20479"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}