{"id":20748,"date":"2025-12-03T16:17:23","date_gmt":"2025-12-03T08:17:23","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=20748"},"modified":"2025-12-03T16:19:05","modified_gmt":"2025-12-03T08:19:05","slug":"https-www-hjtdsm-cn-stem-cells-stem-cell-therapy-20748-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html","title":{"rendered":"\u8102\u80aa\u5e72\u7ec6\u80de\u6cbb\u7597\u6162\u6027\u80be\u75c5\u53ef\u7a33\u5b9a\u77ed\u671f\u80be\u529f\u80fd\uff1a\u4e00\u9879\u57fa\u4e8e\u771f\u5b9e\u4e16\u754c\u6570\u636e\u7684\u5916\u90e8\u5bf9\u7167\u7814\u7a76\uff0834\u4f8bvs170\u4f8b\uff09"},"content":{"rendered":"<section data-role=\"list\">\n<section data-role=\"list\" data-pm-slice=\"4 4 [&quot;para&quot;,{&quot;tagName&quot;:&quot;section&quot;,&quot;attributes&quot;:{&quot;data-role&quot;:&quot;outer&quot;,&quot;label&quot;:&quot;edit by 135editor&quot;,&quot;data-pm-slice&quot;:&quot;0 0 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>\u8102\u80aa\u5e72\u7ec6\u80de\u6cbb\u7597\u6162\u6027\u80be\u75c5\u53ef\u7a33\u5b9a\u77ed\u671f\u80be\u529f\u80fd\uff1a\u4e00\u9879\u57fa\u4e8e\u771f\u5b9e\u4e16\u754c\u6570\u636e\u7684\u5916\u90e8\u5bf9\u7167\u7814\u7a76\uff0834\u4f8bvs170\u4f8b\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#%E4%B8%80%E3%80%81_%E7%A0%94%E7%A9%B6%E8%83%8C%E6%99%AF%EF%BC%9A%E7%96%BE%E7%97%85%E5%9B%B0%E5%A2%83%E4%B8%8E%E6%B2%BB%E7%96%97%E6%96%B0%E5%B8%8C%E6%9C%9B\" >\u4e00\u3001 \u7814\u7a76\u80cc\u666f\uff1a\u75be\u75c5\u56f0\u5883\u4e0e\u6cbb\u7597\u65b0\u5e0c\u671b<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" 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href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#%E4%B8%89%E3%80%81_%E4%B8%B4%E5%BA%8A%E7%BB%93%E6%9E%9C%EF%BC%9A%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E7%96%97%E6%B3%95%E5%B1%95%E7%8E%B0%E6%98%8E%E7%A1%AE%E8%82%BE%E8%84%8F%E4%BF%9D%E6%8A%A4%E4%BD%9C%E7%94%A8\" >\u4e09\u3001 \u4e34\u5e8a\u7ed3\u679c\uff1a\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u5c55\u73b0\u660e\u786e\u80be\u810f\u4fdd\u62a4\u4f5c\u7528<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#31%E3%80%81%E7%A0%94%E7%A9%B6%E9%98%9F%E5%88%97%E4%B8%8E%E5%9F%BA%E7%BA%BF%E7%89%B9%E5%BE%81\" >3.1\u3001\u7814\u7a76\u961f\u5217\u4e0e\u57fa\u7ebf\u7279\u5f81<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#32%E3%80%81ADSC%E6%B2%BB%E7%96%97%E7%BB%84%E4%B8%8ERWD_EC%E7%BB%84%E6%AF%94%E8%BE%83%EF%BC%9AADSC%E6%B2%BB%E7%96%97%E7%A8%B3%E5%AE%9A%E8%82%BE%E5%8A%9F%E8%83%BD%EF%BC%8C%E5%BB%B6%E7%BC%93eGFR%E4%B8%8B%E9%99%8D\" >3.2\u3001ADSC\u6cbb\u7597\u7ec4\u4e0eRWD EC\u7ec4\u6bd4\u8f83\uff1aADSC\u6cbb\u7597\u7a33\u5b9a\u80be\u529f\u80fd\uff0c\u5ef6\u7f13eGFR\u4e0b\u964d<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#33%E3%80%81RWD_EC%E7%BB%84%E4%B8%8EADSC%E6%B2%BB%E7%96%97%E7%BB%84%E6%AF%94%E8%BE%83%EF%BC%9AADSC%E7%BB%84%E6%98%BE%E7%9D%80%E9%99%8D%E4%BD%8E%E8%82%BE%E5%8A%9F%E8%83%BD%E6%81%B6%E5%8C%96%E9%A3%8E%E9%99%A9\" >3.3\u3001RWD EC\u7ec4\u4e0eADSC\u6cbb\u7597\u7ec4\u6bd4\u8f83\uff1aADSC\u7ec4\u663e\u7740\u964d\u4f4e\u80be\u529f\u80fd\u6076\u5316\u98ce\u9669<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#34%E3%80%81%E4%BD%8E%E5%89%82%E9%87%8FADSC%E6%96%B9%E6%A1%88%E6%95%88%E6%9E%9C%E6%9C%80%E4%B8%BA%E7%AA%81%E5%87%BA\" >3.4\u3001\u4f4e\u5242\u91cfADSC\u65b9\u6848\u6548\u679c\u6700\u4e3a\u7a81\u51fa<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#%E5%9B%9B%E3%80%81_%E8%AE%A8%E8%AE%BA%E4%B8%8E%E7%BB%93%E8%AE%BA%EF%BC%9A%E6%84%8F%E4%B9%89%E3%80%81%E5%90%AF%E7%A4%BA%E4%B8%8E%E6%9C%AA%E6%9D%A5%E6%96%B9%E5%90%91\" >\u56db\u3001 \u8ba8\u8bba\u4e0e\u7ed3\u8bba\uff1a\u610f\u4e49\u3001\u542f\u793a\u4e0e\u672a\u6765\u65b9\u5411<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#41%E3%80%81%E7%A0%94%E7%A9%B6%E8%AE%BE%E8%AE%A1%E7%9A%84%E7%A7%91%E5%AD%A6%E4%BB%B7%E5%80%BC\" >4.1\u3001\u7814\u7a76\u8bbe\u8ba1\u7684\u79d1\u5b66\u4ef7\u503c<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#42%E3%80%81%E7%9F%AD%E6%9C%9F%E7%96%97%E6%95%88%E7%9A%84%E4%B8%B4%E5%BA%8A%E4%BB%B7%E5%80%BC%E4%B8%8E%E9%95%BF%E6%9C%9F%E5%B1%95%E6%9C%9B\" >4.2\u3001\u77ed\u671f\u7597\u6548\u7684\u4e34\u5e8a\u4ef7\u503c\u4e0e\u957f\u671f\u5c55\u671b<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#43%E3%80%81%E5%89%82%E9%87%8F-%E5%8F%8D%E5%BA%94%E5%85%B3%E7%B3%BB%E7%9A%84%E6%84%8F%E5%A4%96%E5%8F%91%E7%8E%B0%E4%B8%8E%E6%9C%BA%E5%88%B6%E6%8E%A2%E8%AE%A8\" >4.3\u3001\u5242\u91cf-\u53cd\u5e94\u5173\u7cfb\u7684\u610f\u5916\u53d1\u73b0\u4e0e\u673a\u5236\u63a2\u8ba8<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20748.html\/#44%E3%80%81%E7%BB%BC%E5%90%88%E7%BB%93%E8%AE%BA%E4%B8%8E%E6%9C%AA%E6%9D%A5%E5%B1%95%E6%9C%9B\" >4.4\u3001\u7efc\u5408\u7ed3\u8bba\u4e0e\u672a\u6765\u5c55\u671b<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%E8%84%82%E8%82%AA%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E6%85%A2%E6%80%A7%E8%82%BE%E7%97%85%E5%8F%AF%E7%A8%B3%E5%AE%9A%E7%9F%AD%E6%9C%9F%E8%82%BE%E5%8A%9F%E8%83%BD%EF%BC%9A%E4%B8%80%E9%A1%B9%E5%9F%BA%E4%BA%8E%E7%9C%9F%E5%AE%9E%E4%B8%96%E7%95%8C%E6%95%B0%E6%8D%AE%E7%9A%84%E5%A4%96%E9%83%A8%E5%AF%B9%E7%85%A7%E7%A0%94%E7%A9%B6%EF%BC%8834%E4%BE%8Bvs170%E4%BE%8B%EF%BC%89\"><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8102\u80aa\u5e72\u7ec6\u80de\u6cbb\u7597\u6162\u6027\u80be\u75c5\u53ef\u7a33\u5b9a\u77ed\u671f\u80be\u529f\u80fd\uff1a\u4e00\u9879\u57fa\u4e8e\u771f\u5b9e\u4e16\u754c\u6570\u636e\u7684\u5916\u90e8\u5bf9\u7167\u7814\u7a76\uff0834\u4f8bvs170\u4f8b\uff09<\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e3a\u79d1\u5b66\u8bc4\u4f30\u5176\u4e34\u5e8a\u7597\u6548\uff0c\u6700\u8fd1\uff0c\u4e2d\u56fd\u53f0\u6e7e\u53f0\u5317\u5e02\u53f0\u5317\u533b\u5b66\u5927\u5b66\u516c\u5171\u536b\u751f\u5b66\u9662\u5728\u56fd\u9645\u671f\u520a\u6742\u5fd7\u300a\u4e34\u5e8a\u8f6c\u5316\u4e0e\u79d1\u5b66\u300b\u4e3b\u9875\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u6807\u9898\u4e3a\u201c<\/span><\/span><a href=\"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/10.1111\/cts.70415\" target=\"_blank\" rel=\"noopener nofollow\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u91c7\u7528\u771f\u5b9e\u4e16\u754c\u6570\u636e\u4f5c\u4e3a\u5916\u90e8\u5bf9\u7167\u8bc4\u4f30\u5f02\u4f53\u8102\u80aa\u6765\u6e90\u5e72\u7ec6\u80de\u6cbb\u7597\u665a\u671f\u6162\u6027\u80be\u810f\u75c5\u7684\u7597\u6548<\/span><\/span><\/a><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u201d\u7684\u7814\u7a76\u7efc\u8ff0<\/span><\/span><sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[1]<\/span><\/span><\/sup><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">The<\/span><\/span><\/p>\n<section><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-20756 aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-03_140928_119.png\" alt=\"\" width=\"711\" height=\"349\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-03_140928_119.png 711w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-03_140928_119-300x147.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-03_140928_119-18x9.png 18w\" sizes=\"(max-width: 711px) 100vw, 711px\" \/><\/section>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7ed3\u679c\u663e\u793a\uff1a\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u53ef\u80fd\u6709\u52a9\u4e8e\u7a33\u5b9a\u6162\u6027\u80be\u75c5\u60a3\u8005\u7684\u77ed\u671f\u80be\u529f\u80fd\uff0c\u5c24\u5176\u5bf9\u665a\u671fCKD\u60a3\u8005\u66f4\u4e3a\u6709\u6548\u3002\u5c24\u5176\u662f\u5728\u75c5\u60c5\u8f83\u91cd\u7684\u60a3\u8005\u4e2d\u3002\u5728\u6240\u6709\u5242\u91cf\u7ec4\u4e2d\uff0c\u4f4e\u5242\u91cf\u7ec4\u7684\u80be\u529f\u80fd\u7a33\u5b9a\u6027\u6700\u4f73\u3002\u8fd9\u4e9b\u53d1\u73b0\u652f\u6301\u5229\u7528\u771f\u5b9e\u4e16\u754c\u6570\u636e\u6784\u5efa\u5916\u90e8\u5bf9\u7167\u7684\u53ef\u884c\u6027\uff0c\u5e76\u63d0\u793a\u5e72\u7ec6\u80de\u7597\u6cd5\u53ef\u80fd\u5bf9\u80be\u529f\u80fd\u5177\u6709\u77ed\u671f\u7a33\u5b9a\u4f5c\u7528\u3002<\/span><\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E4%B8%80%E3%80%81_%E7%A0%94%E7%A9%B6%E8%83%8C%E6%99%AF%EF%BC%9A%E7%96%BE%E7%97%85%E5%9B%B0%E5%A2%83%E4%B8%8E%E6%B2%BB%E7%96%97%E6%96%B0%E5%B8%8C%E6%9C%9B\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e00\u3001 \u7814\u7a76\u80cc\u666f\uff1a\u75be\u75c5\u56f0\u5883\u4e0e\u6cbb\u7597\u65b0\u5e0c\u671b<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">CKD\u7684\u75be\u75c5\u8d1f\u62c5\u4e0e\u6cbb\u7597\u5c40\u9650\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20341.html\/\" target=\"_blank\" rel=\"nofollow noopener\">\u6162\u6027\u80be\u810f\u75c5\uff08CKD\uff09<\/a>\u662f\u5168\u7403\u7ea610%\u4eba\u53e3\u7f79\u60a3\u7684\u5e38\u89c1\u75c5\uff0c\u5176\u5b9a\u4e49\u4e3a\u80be\u810f\u7ed3\u6784\u6216\u529f\u80fd\u6301\u7eed\u5f02\u5e38\u8d85\u8fc73\u4e2a\u6708\uff0c\u4e14\u901a\u5e38\u4e0d\u53ef\u9006\u8f6c\u3002\u75be\u75c5\u8fdb\u5c55\u4f1a\u5f15\u53d1\u5fc3\u8840\u7ba1\u75be\u75c5\u3001\u9ad8\u8840\u538b\u7b49\u591a\u79cd\u5e76\u53d1\u75c7\uff0c\u80be\u5c0f\u7ba1\u95f4\u8d28\u7ea4\u7ef4\u5316\u662f\u5bfc\u81f4\u80be\u529f\u80fd\u6301\u7eed\u4e0b\u964d\u7684\u5173\u952e\u75c5\u7406\u8fc7\u7a0b\u3002<\/span><\/span><\/p>\n<section><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20749 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-1410466223-612x612-1.jpg\" alt=\"\u5f02\u4f53\u8102\u80aa\u5e72\u7ec6\u80de\u6cbb\u7597\u6162\u6027\u80be\u75c5\u53ef\u7a33\u5b9a\u77ed\u671f\u80be\u529f\u80fd\uff1a\u4e00\u9879\u57fa\u4e8e\u771f\u5b9e\u4e16\u754c\u6570\u636e\u7684\u5916\u90e8\u5bf9\u7167\u7814\u7a76\uff0834\u4f8bvs170\u4f8b\uff09\" width=\"612\" height=\"408\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-1410466223-612x612-1.jpg 612w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-1410466223-612x612-1-300x200.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-1410466223-612x612-1-18x12.jpg 18w\" sizes=\"(max-width: 612px) 100vw, 612px\" \/><\/section>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c3d\u7ba1\u73b0\u6709\u836f\u7269\uff08\u5982RAAS\u6291\u5236\u5242\u3001SGLT2\u6291\u5236\u5242\u7b49\uff09\u53ef\u5ef6\u7f13CKD\u8fdb\u5c55\uff0c\u4f46\u665a\u671f\u60a3\u8005\u4ecd\u9762\u4e34\u80be\u529f\u80fd\u8fc5\u901f\u6076\u5316\u7684\u56f0\u5883\uff0c\u56e0\u6b64\u4e9f\u9700\u5f00\u53d1\u521b\u65b0\u7597\u6cd5\u3002\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u56e0\u5176\u4fc3\u8fdb\u80be\u810f\u4fee\u590d\u548c\u518d\u751f\u7684\u80fd\u529b\u800c\u5907\u53d7\u5173\u6ce8\uff0c\u5df2\u6210\u4e3a\u9884\u9632CKD\u8fdb\u5c55\u7684\u6f5c\u5728\u6cbb\u7597\u65b9\u6cd5\u3002<\/span><\/span><\/p>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5f02\u4f53\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u6162\u6027\u80be\u75c5\u7684\u4fee\u590d\u6f5c\u529b\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8fd1\u671f\u7814\u7a76\u8868\u660e\uff0c<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20558.html\/\" target=\"_blank\" rel=\"nofollow noopener\">mesenchymal stem cell MSC (in cell biology)<\/a>\u53ef\u901a\u8fc7\u65c1\u5206\u6ccc\u673a\u5236\u5206\u6ccc\u7ec6\u80de\u56e0\u5b50\u3001\u8d8b\u5316\u56e0\u5b50\u548c\u751f\u957f\u56e0\u5b50\uff0c\u4ece\u800c\u6291\u5236\u90bb\u8fd1\u7ec6\u80de\u51cb\u4ea1\uff0c\u4fc3\u8fdb\u7ec6\u80de\u589e\u6b96\u3001\u8840\u7ba1\u751f\u6210\u548c\u7ec4\u7ec7\u518d\u751f\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5229\u7528\u80be\u635f\u4f24\u5c0f\u9f20\u6a21\u578b\u7684\u7814\u7a76\u8868\u660e\uff0c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6765\u6e90\u7684\u7ec6\u80de\u5916\u56ca\u6ce1\u80fd\u591f\u6291\u5236\u4fc3\u708e\u56e0\u5b50\uff0c\u540c\u65f6\u589e\u5f3a\u6297\u708e\u53cd\u5e94\uff0c\u4ece\u800c\u53d1\u6325\u514d\u75ab\u8c03\u8282\u4f5c\u7528\uff0c\u6291\u5236\u80be\u5c0f\u7ba1\u4e0a\u76ae\u7ec6\u80de\u7126\u4ea1\u548c\u708e\u75c7\uff0c\u51cf\u8f7b\u80be\u7ea4\u7ef4\u5316\uff0c\u5e76\u4fc3\u8fdb\u7ec6\u80de\u4fee\u590d\u3002\u5728\u5404\u79cd\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6765\u6e90\u4e2d\uff0c\u8102\u80aa\u7ec4\u7ec7\u6765\u6e90\u7684\u5e72\u7ec6\u80de\uff08ADSCs\uff09\u4e0e\u9aa8\u9ad3\u6765\u6e90\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08BMSCs\uff09\u76f8\u6bd4\uff0c\u8868\u73b0\u51fa\u66f4\u4f18\u5f02\u7684\u6297\u708e\u548c\u514d\u75ab\u8c03\u8282\u7279\u6027\u3002<\/span><\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E7%8E%B0%E9%98%B6%E6%AE%B5%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E6%99%9A%E6%9C%9F%E6%85%A2%E6%80%A7%E8%82%BE%E7%97%85%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%E7%9A%84%E7%93%B6%E9%A2%88%E4%B8%8E%E6%8C%91%E6%88%98\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u73b0\u9636\u6bb5\u5e72\u7ec6\u80de\u6cbb\u7597\u665a\u671f\u6162\u6027\u80be\u75c5\u4e34\u5e8a\u8bd5\u9a8c\u7684\u74f6\u9888\u4e0e\u6311\u6218<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5f53\u524d\u8bb8\u591aMSC\u6cbb\u7597CKD\u7684\u4e34\u5e8a\u8bd5\u9a8c\u53d7\u9650\u4e8e\u4f26\u7406\u4e0e\u7ecf\u6d4e\u56e0\u7d20\uff0c\u7f3a\u4e4f\u968f\u673a\u5bf9\u7167\u7ec4\uff0c\u5f71\u54cd\u4e86\u7597\u6548\u8bc4\u4f30\u7684\u53ef\u9760\u6027\u4e0e\u6709\u6548\u6027\u3002\u8fd9\u4e00\u8bbe\u8ba1\u7f3a\u9677\u4f7f\u5f97\u96be\u4ee5\u51c6\u786e\u8861\u91cf\u6cbb\u7597\u4f5c\u7528\u7684\u51c0\u6548\u76ca\uff0c\u4e5f\u5236\u7ea6\u4e86\u7814\u7a76\u7ed3\u679c\u7684\u4e34\u5e8a\u8f6c\u5316\u4e0e\u76d1\u7ba1\u5ba1\u6279\u3002<\/span><\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E5%BA%94%E7%94%A8%E7%9C%9F%E5%AE%9E%E4%B8%96%E7%95%8C%E6%95%B0%E6%8D%AE%E8%AF%84%E4%BC%B0%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E6%85%A2%E6%80%A7%E8%82%BE%E7%97%85%E7%9C%9F%E5%AE%9E%E7%96%97%E6%95%88%E4%B8%BA%E4%BD%95%E8%87%B3%E5%85%B3%E9%87%8D%E8%A6%81%EF%BC%9F\"><\/span><strong>\u5e94\u7528\u771f\u5b9e\u4e16\u754c\u6570\u636e\u8bc4\u4f30\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u6162\u6027\u80be\u75c5\u771f\u5b9e\u7597\u6548\u4e3a\u4f55\u81f3\u5173\u91cd\u8981\uff1f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5e94\u7528\u771f\u5b9e\u4e16\u754c\u6570\u636e\uff08RWD\uff09\u8bc4\u4f30\u5e72\u7ec6\u80de\u6cbb\u7597\u80be\u75c5\u7684\u7597\u6548\u4e4b\u6240\u4ee5\u81f3\u5173\u91cd\u8981\uff0c\u6838\u5fc3\u5728\u4e8e\u5b83\u80fd\u6709\u6548\u89e3\u51b3\u6b64\u7c7b\u521b\u65b0\u7597\u6cd5\u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u6839\u672c\u6027\u8bbe\u8ba1\u7f3a\u9677\u3002\u5e72\u7ec6\u80de\u7597\u6cd5\u7684I\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5927\u591a\u4e3a\u5355\u81c2\u8bbe\u8ba1\uff0c\u7f3a\u4e4f\u5185\u7f6e\u5bf9\u7167\u7ec4\uff0c\u96be\u4ee5\u533a\u5206\u6cbb\u7597\u6548\u5e94\u4e0e\u75be\u75c5\u7684\u81ea\u7136\u8fdb\u7a0b\u3002\u901a\u8fc7\u91c7\u7528\u76ee\u6807\u8bd5\u9a8c\u6a21\u62df\u7b49\u65b9\u6cd5\uff0cRWD\u53ef\u4ee5\u6784\u5efa\u4e00\u4e2a\u4e0e\u8bd5\u9a8c\u7ec4\u60a3\u8005\u57fa\u7ebf\u7279\u5f81\u9ad8\u5ea6\u76f8\u4f3c\u7684\u5916\u90e8\u5bf9\u7167\u7ec4\uff0c\u4ece\u800c\u5f25\u8865\u968f\u673a\u5316\u5bf9\u7167\u7684\u7f3a\u5931\uff0c\u6700\u5927\u7a0b\u5ea6\u5730\u51cf\u5c11\u504f\u501a\uff0c\u4e3a\u7597\u6548\u8bc4\u4f30\u63d0\u4f9b\u4e00\u4e2a\u4e25\u8c28\u3001\u53ef\u9760\u7684\u79d1\u5b66\u6bd4\u8f83\u6846\u67b6\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8fd9\u79cd\u65b9\u6cd5\u7684\u5b9e\u8df5\u4ef7\u503c\u4e0e\u6df1\u8fdc\u610f\u4e49\u4f53\u73b0\u5728\u591a\u4e2a\u200b\u200b\u5c42\u9762\u3002\u5177\u4f53\u800c\u8a00\uff0c\u5b83\u4f7f\u5f97\u5bf9\u5355\u81c2\u8bd5\u9a8c\u7ed3\u679c\u7684\u89e3\u8bfb\u4ece\u63cf\u8ff0\u6027\u63d0\u5347\u5230\u53ef\u6bd4\u8f83\u7684\u5206\u6790\u5c42\u6b21\uff0c\u663e\u7740\u589e\u5f3a\u4e86\u8bc1\u636e\u5f3a\u5ea6\u3002\u4ee5\u672c\u7814\u7a76\u4e3a\u4f8b\uff0c\u6b63\u662f\u901a\u8fc7\u6574\u5408\u53f0\u5317\u533b\u5b66\u5927\u5b66\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u5e93\uff08TMUCRD\uff09\u4e2d\u7684\u5e38\u89c4\u6cbb\u7597\u60a3\u8005\u6570\u636e\u4f5c\u4e3a\u5bf9\u7167\uff0c\u624d\u5f97\u4ee5\u5ba2\u89c2\u8bc4\u4f30\u8102\u80aa\u5e72\u7ec6\u80de\u7597\u6cd5\u5ef6\u7f13\u80be\u75c5\u8fdb\u5c55\u7684\u771f\u5b9e\u6548\u679c\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6b64\u5916\uff0cRWD\u63d0\u4f9b\u7684\u8bc1\u636e\u4e0d\u4ec5\u6709\u52a9\u4e8e\u66f4\u53ef\u9760\u7684\u4e34\u5e8a\u51b3\u7b56\uff0c\u4e5f\u4e3a\u652f\u6301\u76d1\u7ba1\u5ba1\u6279\u63d0\u4f9b\u4e86\u6765\u81ea\u771f\u5b9e\u4e16\u754c\u7684\u5173\u952e\u8865\u5145\u8bc1\u636e\uff0c\u662f\u63a8\u52a8\u6709\u524d\u666f\u7684\u5e72\u7ec6\u80de\u7597\u6cd5\u4ece\u65e9\u671f\u8bd5\u9a8c\u8d70\u5411\u5b9e\u9645\u5e94\u7528\u4e0d\u53ef\u6216\u7f3a\u7684\u6865\u6881\u3002<\/span><\/span><\/p>\n<section>\n<h2><span class=\"ez-toc-section\" id=\"%E4%BA%8C%E3%80%81_%E6%9D%90%E6%96%99%E4%B8%8E%E6%96%B9%E6%B3%95%EF%BC%9A%E4%B8%A5%E8%B0%A8%E8%AE%BE%E8%AE%A1%E7%A1%AE%E4%BF%9D%E5%8F%AF%E6%AF%94%E6%80%A7\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e8c\u3001 \u6750\u6599\u4e0e\u65b9\u6cd5\uff1a\u4e25\u8c28\u8bbe\u8ba1\u786e\u4fdd\u53ef\u6bd4\u6027<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/section>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6570\u636e\u6765\u6e90\u4e0e\u7814\u7a76\u5bf9\u8c61\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u672c\u7814\u7a76\u6570\u636e\u6e90\u81ea\u4e00\u9879\u8bc4\u4f30\u5f02\u4f53ADSC\u7597\u6cd5\uff08ELIXCYTE\uff09\u7684I\/II\u671f\u5355\u81c2\u4e34\u5e8a\u8bd5\u9a8c\uff08\u517139\u540d\u53d7\u8bd5\u8005\uff0c\u5206\u4f4e\u3001\u4e2d\u3001\u9ad8\u4e09\u4e2a\u5242\u91cf\u7ec4\uff09\u4ee5\u53ca\u53f0\u5317\u533b\u5b66\u5927\u5b66\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u5e93\uff08TMUCRD\uff09\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5728I\u671f\u5171\u670912\u540d\u53d7\u8bd5\u8005\u53c2\u4e0e\uff0cII\u671f\u5171\u670927\u540d\u53d7\u8bd5\u8005\u53c2\u4e0e\u3002\u5176\u4e2d\uff0c12\u540d\u53d7\u8bd5\u8005\u63a5\u53d7\u4e86\u4f4e\u5242\u91cf\uff08ADSC6.4\u00d710\u2077\u4e2a\u7ec6\u80de\uff09\u7684ADSC\u6cbb\u7597\uff0c12\u540d\u53d7\u8bd5\u8005\u63a5\u53d7\u4e86\u4e2d\u7b49\u5242\u91cf\uff08ADSC19.2\u00d710\u2077\u4e2a\u7ec6\u80de\uff09\u7684ADSC\u6cbb\u7597\uff0c15\u540d\u53d7\u8bd5\u8005\u63a5\u53d7\u4e86\u9ad8\u5242\u91cf\uff08ADSC32.0\u00d710\u2077\u4e2a\u7ec6\u80de\uff09\u7684ADSC\u6cbb\u7597\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">TMUCRD\u5305\u542b\u4e86\u7ea62.4\u4e07\u540d\u63a5\u53d7\u5e38\u89c4\u6cbb\u7597\u7684CKD\u60a3\u8005\u7684\u7eb5\u5411\u4fe1\u606f\u3002\u7814\u7a76\u4e25\u683c\u9075\u5faa\u4f26\u7406\u89c4\u8303\uff0c\u6240\u6709\u6570\u636e\u5747\u7ecf\u6279\u51c6\u5e76\u4f7f\u7528\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u75c5\u4f8b\u7ec4\u4e3a\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7b26\u5408\u6761\u4ef6\uff0820-80\u5c81\uff0cCKD 3b-4\u671f\uff09\u768434\u540d\u60a3\u8005\u3002\u5bf9\u7167\u7ec4\u5219\u4eceTMUCRD\u4e2d\u4f9d\u636e\u4e0e\u75c5\u4f8b\u7ec4\u5b8c\u5168\u76f8\u540c\u7684\u7eb3\u5165\u4e0e\u6392\u9664\u6807\u51c6\uff08\u5982\u6392\u9664\u7279\u5b9a\u5408\u5e76\u75c7\u3001\u672a\u63a7\u5236\u7cd6\u5c3f\u75c5\u7b49\uff09\u8fdb\u884c\u521d\u6b65\u7b5b\u9009\uff0c\u5f97\u52302384\u540d\u6f5c\u5728\u5bf9\u7167\u3002<\/span><\/span><\/p>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7814\u7a76\u8bbe\u8ba1\u4e0e\u7edf\u8ba1\u5339\u914d\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e3a\u786e\u4fdd\u4e24\u7ec4\u53ef\u6bd4\u6027\uff0c\u7814\u7a76\u91c7\u7528\u503e\u5411\u6027\u8bc4\u5206\u5339\u914d\uff08PSM\uff09\u65b9\u6cd5\uff0c\u4ee51:5\u7684\u6bd4\u4f8b\u4e3a\u6bcf\u4f8b\u75c5\u4f8b\u5339\u914d5\u4f8b\u5bf9\u7167\u3002\u6700\u7ec8\u6210\u529f\u6784\u5efa\u4e86\u4e00\u4e2a\u753134\u4f8bADSC\u6cbb\u7597\u7ec4\u60a3\u8005\u548c170\u4f8bRWD\u5916\u90e8\u5bf9\u7167\u7ec4\u60a3\u8005\u7ec4\u6210\u7684\u3001\u57fa\u7ebf\u7279\u5f81\uff08\u5305\u62ec\u5e74\u9f84\u3001\u6027\u522b\u3001CKD\u5206\u671f\u3001\u5408\u5e76\u75c7\u53ca\u7528\u836f\uff09\u65e0\u7edf\u8ba1\u5b66\u5dee\u5f02\u7684\u5206\u6790\u961f\u5217\uff0c\u6709\u6548\u51cf\u5c11\u4e86\u6df7\u6742\u504f\u501a\uff08\u56fe1\uff09\u3002<\/span><\/span><\/p>\n<section>\n<div id=\"attachment_20755\" style=\"width: 1681px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20755\" class=\"wp-image-20755 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0001-m-scaled.jpg\" alt=\"\" width=\"1671\" height=\"2560\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0001-m-scaled.jpg 1671w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0001-m-196x300.jpg 196w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0001-m-668x1024.jpg 668w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0001-m-768x1177.jpg 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0001-m-1002x1536.jpg 1002w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0001-m-1336x2048.jpg 1336w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0001-m-8x12.jpg 8w\" sizes=\"(max-width: 1671px) 100vw, 1671px\" \/><p id=\"caption-attachment-20755\" class=\"wp-caption-text\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u56fe1\uff1a\u7814\u7a76\u6d41\u7a0b\u56fe<\/span><\/span><\/p><\/div>\n<\/section>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7597\u6548\u8bc4\u4ef7\u6307\u6807\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7814\u7a76\u91c7\u7528\u4e24\u4e2a\u6838\u5fc3\u6307\u6807\u8bc4\u4f30\u80be\u529f\u80fd\u53d8\u5316\u3002<\/span><\/span><\/p>\n<section data-role=\"list\">\n<section data-role=\"list\">\n<ul class=\"list-paddingleft-1\">\n<li><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u2460\u4e3b\u8981\u6307\u6807\u662feGFR\u76f8\u5bf9\u4e8e\u57fa\u7ebf\u7684\u5e73\u5747\u767e\u5206\u6bd4\u53d8\u5316\uff0c\u7528\u4e8e\u8861\u91cf\u80be\u529f\u80fd\u7684\u52a8\u6001\u6ce2\u52a8\u4e0e\u77ed\u671f\u7a33\u5b9a\u6027\u3002<\/span><\/span><\/li>\n<\/ul>\n<\/section>\n<section data-role=\"list\">\n<ul class=\"list-paddingleft-1\">\n<li><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u2461\u5173\u952e\u6b21\u8981\u6307\u6807\u662feGFR\u8f83\u57fa\u7ebf\u4e0b\u964d\u226530%\u7684\u53d1\u751f\u7387\uff0c\u8fd9\u662f\u4e00\u4e2a\u88ab\u5e7f\u6cdb\u8ba4\u53ef\u7684CKD\u8fdb\u5c55\u7684\u4e34\u5e8a\u7ec8\u70b9\u3002\u6b64\u5916\uff0c\u7814\u7a76\u4e5f\u5c06eGFR\u4e0b\u964d15%\u300120%\u300125%\u53ca35%\u7684\u53d1\u751f\u7387\u4f5c\u4e3a\u6b21\u8981\u6307\u6807\u8fdb\u884c\u8003\u5bdf\uff0c\u4ee5\u591a\u89d2\u5ea6\u8bc4\u4f30\u80be\u529f\u80fd\u6076\u5316\u60c5\u51b5\u3002<\/span><\/span><\/li>\n<\/ul>\n<\/section>\n<\/section>\n<h2><span class=\"ez-toc-section\" id=\"%E4%B8%89%E3%80%81_%E4%B8%B4%E5%BA%8A%E7%BB%93%E6%9E%9C%EF%BC%9A%E8%84%82%E8%82%AA%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E7%96%97%E6%B3%95%E5%B1%95%E7%8E%B0%E6%98%8E%E7%A1%AE%E8%82%BE%E8%84%8F%E4%BF%9D%E6%8A%A4%E4%BD%9C%E7%94%A8\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e09\u3001 \u4e34\u5e8a\u7ed3\u679c\uff1a\u8102\u80aa\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u5c55\u73b0\u660e\u786e\u80be\u810f\u4fdd\u62a4\u4f5c\u7528<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"31%E3%80%81%E7%A0%94%E7%A9%B6%E9%98%9F%E5%88%97%E4%B8%8E%E5%9F%BA%E7%BA%BF%E7%89%B9%E5%BE%81\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">3.1\u3001\u7814\u7a76\u961f\u5217\u4e0e\u57fa\u7ebf\u7279\u5f81<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u672c\u7814\u7a76\u91c7\u7528\u503e\u5411\u8bc4\u5206\u5339\u914d\uff08PSM\uff09\u6784\u5efa\u4e86\u53ef\u6bd4\u961f\u5217\uff0c\u6700\u7ec8\u5206\u6790\u961f\u5217\u5305\u542b34\u4f8bADSC\u6cbb\u7597\u7ec4\u60a3\u8005\u548c170\u4f8b\u771f\u5b9e\u4e16\u754c\u6570\u636e\u5916\u90e8\u5bf9\u7167\u7ec4\u60a3\u8005\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5339\u914d\u540e\uff0c\u4e24\u7ec4\u57fa\u7ebf\u7279\u5f81\u5e73\u8861\uff0c\u65e0\u7edf\u8ba1\u5b66\u5dee\u5f02\uff1a\u961f\u5217\u4e2d62%\u4e3a\u7537\u6027\uff0c\u5e73\u5747\u5e74\u9f8451-53\u5c81\uff0c\u6162\u6027\u80be\u810f\u75c5\uff08CKD\uff094\u671f\u60a3\u8005\u536067.65%\uff0c\u8d85\u8fc785%\u7684\u60a3\u8005\u63a5\u53d7\u4e86\u80be\u7d20-\u8840\u7ba1\u7d27\u5f20\u7d20-\u919b\u56fa\u916e\u7cfb\u7edf\u6291\u5236\u5242\u6cbb\u7597\uff0c\u786e\u4fdd\u4e86\u540e\u7eed\u7597\u6548\u6bd4\u8f83\u7684\u53ef\u9760\u6027\u3002<\/span><\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"32%E3%80%81ADSC%E6%B2%BB%E7%96%97%E7%BB%84%E4%B8%8ERWD_EC%E7%BB%84%E6%AF%94%E8%BE%83%EF%BC%9AADSC%E6%B2%BB%E7%96%97%E7%A8%B3%E5%AE%9A%E8%82%BE%E5%8A%9F%E8%83%BD%EF%BC%8C%E5%BB%B6%E7%BC%93eGFR%E4%B8%8B%E9%99%8D\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">3.2\u3001ADSC\u6cbb\u7597\u7ec4\u4e0eRWD EC\u7ec4\u6bd4\u8f83\uff1aADSC\u6cbb\u7597\u7a33\u5b9a\u80be\u529f\u80fd\uff0c\u5ef6\u7f13eGFR\u4e0b\u964d<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5982\u56fe2A\u90e8\u5206\u6240\u793a\uff0c\u4e0eRWD EC\u7ec4\u76f8\u6bd4\uff0cADSC\u6cbb\u7597\u7ec4\u7684eGFR\u8f68\u8ff9\u66f4\u4e3a\u7a33\u5b9a\uff0c\u4e0b\u964d\u901f\u5ea6\u4e5f\u66f4\u6162\u3002\u6309CKD\u5206\u671f\u5206\u5c42\u5206\u6790\u663e\u793a\uff0c\u5728CKD3\u671f\uff0c\u4e24\u7ec4\u7684eGFR\u5747\u4fdd\u6301\u7a33\u5b9a\uff1b\u800c\u5728CKD4\u671f\uff0cRWD EC\u7ec4\u7684eGFR\u4e0b\u964d\u5e45\u5ea6\u663e\u7740\u66f4\u5927\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6b64\u5916\uff0cADSC\u6cbb\u7597\u7ec4\u7684eGFR\u53d8\u5f02\u6027\u66f4\u9ad8\uff0c\u8868\u73b0\u4e3a\u6807\u51c6\u5dee\u66f4\u5927\u3002\u56fe2B\u90e8\u5206\u5c55\u793a\u4e86eGFR\u76f8\u5bf9\u4e8e\u57fa\u7ebf\u7684\u767e\u5206\u6bd4\u53d8\u5316\uff0c\u7ed3\u679c\u663e\u793aRWD EC\u7ec4\u7684eGFR\u53d8\u5316\u504f\u79bb0%\u66f4\u4e3a\u663e\u7740\uff0c\u53cd\u6620\u51fa\u5176\u80be\u529f\u80fd\u968f\u65f6\u95f4\u63a8\u79fb\u6ce2\u52a8\u66f4\u5927\uff0c\u800cADSC\u6cbb\u7597\u7ec4\u5219\u4fdd\u6301\u76f8\u5bf9\u7a33\u5b9a\u3002<\/span><\/span><\/p>\n<section>\n<div id=\"attachment_20754\" style=\"width: 2086px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20754\" class=\"wp-image-20754 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0002-m-scaled.jpg\" alt=\"\" width=\"2076\" height=\"2560\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0002-m-scaled.jpg 2076w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0002-m-243x300.jpg 243w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0002-m-830x1024.jpg 830w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0002-m-768x947.jpg 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0002-m-1246x1536.jpg 1246w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0002-m-1661x2048.jpg 1661w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0002-m-10x12.jpg 10w\" sizes=\"(max-width: 2076px) 100vw, 2076px\" \/><p id=\"caption-attachment-20754\" class=\"wp-caption-text\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u56fe2\uff1a\u6bd4\u8f83ADSC\u6cbb\u7597\u7ec4\u548c\u771f\u5b9e\u4e16\u754c\u6570\u636e\u5916\u90e8\u5bf9\u7167\u7ec4\u5728\u4e0d\u540cCKD\u5206\u671f\u4e0b\u7684eGFR\u8d8b\u52bf\u548c\u968f\u65f6\u95f4\u53d8\u5316\u7684\u767e\u5206\u6bd4\u3002<\/span><\/span><\/p><\/div>\n<\/section>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5728CKD3\u671f\uff0c\u4e24\u7ec4\u7684eGFR\u767e\u5206\u6bd4\u53d8\u5316\u65e0\u663e\u7740\u5dee\u5f02\uff0c\u8868\u660e\u603b\u4f53\u7a33\u5b9a\u6027\u826f\u597d\u3002\u7136\u800c\uff0c\u5728CKD4\u671f\uff0cRWD EC\u7ec4\u4e0eADSC\u6cbb\u7597\u7ec4\u76f8\u6bd4\u51fa\u73b0\u4e86\u7edf\u8ba1\u5b66\u4e0a\u7684\u663e\u7740\u4e0b\u964d\uff0c\u8fd9\u8868\u660e\u5728\u665a\u671fCKD\u60a3\u8005\u4e2d\uff0cADSC\u6cbb\u7597\u7ec4\u7684\u77ed\u671f\u80be\u529f\u80fd\u8f68\u8ff9\u66f4\u52a0\u7a33\u5b9a\u3002<\/span><\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"33%E3%80%81RWD_EC%E7%BB%84%E4%B8%8EADSC%E6%B2%BB%E7%96%97%E7%BB%84%E6%AF%94%E8%BE%83%EF%BC%9AADSC%E7%BB%84%E6%98%BE%E7%9D%80%E9%99%8D%E4%BD%8E%E8%82%BE%E5%8A%9F%E8%83%BD%E6%81%B6%E5%8C%96%E9%A3%8E%E9%99%A9\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">3.3\u3001RWD EC\u7ec4\u4e0eADSC\u6cbb\u7597\u7ec4\u6bd4\u8f83\uff1aADSC\u7ec4\u663e\u7740\u964d\u4f4e\u80be\u529f\u80fd\u6076\u5316\u98ce\u9669<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5728ADSC\u6cbb\u7597\u7ec4\u548cRWD EC\u7ec4\u4e2d\uff0c\u6211\u4eec\u8bc4\u4f30\u4e86\u4e0d\u540ceGFR\u4e0b\u964d\u9608\u503c\u4e0b\u80be\u529f\u80fd\u4e0b\u964d\u7684\u98ce\u9669\uff0c\u5e76\u6309\u603b\u4f53\u4eba\u7fa4\u3001CKD 3B\u671f\u548cCKD 4\u671f\u8fdb\u884c\u5206\u5c42\uff08\u56fe3\uff09\u3002<\/span><\/span><\/p>\n<section>\n<div id=\"attachment_20753\" style=\"width: 2138px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20753\" class=\"wp-image-20753 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0003-m.jpg\" alt=\"\" width=\"2128\" height=\"1843\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0003-m.jpg 2128w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0003-m-300x260.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0003-m-1024x887.jpg 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0003-m-768x665.jpg 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0003-m-1536x1330.jpg 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0003-m-2048x1774.jpg 2048w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0003-m-14x12.jpg 14w\" sizes=\"(max-width: 2128px) 100vw, 2128px\" \/><p id=\"caption-attachment-20753\" class=\"wp-caption-text\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u56fe3\uff1a\u672c\u7814\u7a76\u6bd4\u8f83\u4e86\u5728\u6240\u6709\u60a3\u8005\u4ee5\u53caCKD 3B\u671f\u548c4\u671f\u60a3\u8005\u4e2d\uff0cADSC\u6cbb\u7597\u7ec4\u548cRWD\u5bf9\u7167\u7ec4\u5728\u4e0d\u540ceGFR\u4e0b\u964d\u9608\u503c\u4e0b\u7684\u80be\u529f\u80fd\u4e0b\u964d\u98ce\u9669\u3002<\/span><\/span><\/p><\/div>\n<\/section>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u98ce\u9669\u5206\u6790\u8bc1\u5b9e\uff0cADSC\u6cbb\u7597\u80fd\u5927\u5e45\u964d\u4f4e\u80be\u529f\u80fd\u6076\u5316\u98ce\u9669\uff1a<\/span><\/span><\/p>\n<section data-role=\"list\">\n<section data-role=\"list\">\n<section data-role=\"list\">\n<ul class=\"list-paddingleft-1\">\n<li><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u603b\u4f53\u4eba\u7fa4\u4e2d\uff0ceGFR\u4e0b\u964d\u226530%\u7684\u98ce\u9669\u6bd4\uff08HR\uff09\u4e3a0.276\uff0c\u610f\u5473\u7740\u98ce\u9669\u964d\u4f4e\u4e86\u7ea672.4%\uff08p&lt;0.05\uff09\u3002<\/span><\/span><\/li>\n<\/ul>\n<\/section>\n<\/section>\n<section data-role=\"list\">\n<ul class=\"list-paddingleft-1\">\n<li><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5728CKD4\u671f\u4e9a\u7ec4\u4e2d\uff0ceGFR\u4e0b\u964d\u226515%\u548c\u226530%\u7684\u98ce\u9669\u4e5f\u5206\u522b\u663e\u7740\u964d\u4f4e55.8%\uff08HR=0.442\uff09\u548c72.4%\uff08HR=0.276\uff09\u3002<\/span><\/span><\/li>\n<\/ul>\n<\/section>\n<\/section>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Kaplan-Meier\u751f\u5b58\u5206\u6790\u8fdb\u4e00\u6b65\u663e\u793a\uff08\u56fe4\uff09\uff0c\u5bf9\u7167\u7ec4\u8fbe\u5230eGFR\u4e0b\u964d30%\u7ec8\u70b9\u7684\u7d2f\u79ef\u98ce\u9669\u901f\u5ea6\uff0c\u5728\u603b\u4f53\u4eba\u7fa4\u548cCKD 4\u671f\u60a3\u8005\u4e2d\u5747\u663e\u7740\u5feb\u4e8eADSC\u6cbb\u7597\u7ec4\uff08p\u503c\u5206\u522b\u4e3a0.0153\u548c0.0317\uff09\u3002<\/span><\/span><\/p>\n<section>\n<div id=\"attachment_20752\" style=\"width: 1927px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20752\" class=\"wp-image-20752 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0004-m-scaled.jpg\" alt=\"\" width=\"1917\" height=\"2560\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0004-m-scaled.jpg 1917w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0004-m-225x300.jpg 225w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0004-m-767x1024.jpg 767w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0004-m-768x1026.jpg 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0004-m-1150x1536.jpg 1150w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0004-m-1533x2048.jpg 1533w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0004-m-9x12.jpg 9w\" sizes=\"(max-width: 1917px) 100vw, 1917px\" \/><p id=\"caption-attachment-20752\" class=\"wp-caption-text\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u56fe4\uff1a\u672c\u7814\u7a76\u5bf9\u6162\u6027\u80be\u810f\u75c5\uff08CKD\uff09\u5404\u9636\u6bb5\u7684ADSC\u6cbb\u7597\u7ec4\u548cRWD\u5bf9\u7167\u7ec4\u8fdb\u884c\u4e86\u80be\u529f\u80fd\u4e0b\u964d\u7684\u7d2f\u79ef\u98ce\u9669\u5206\u6790\u3002<\/span><\/span><\/p><\/div>\n<\/section>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8fd9\u5171\u540c\u8868\u660e\uff0cADSC\u6cbb\u7597\u80fd\u6709\u6548\u5ef6\u7f13\u80be\u529f\u80fd\u8870\u9000\u7684\u901f\u5ea6\uff0c\u4e3a\u665a\u671f\u6162\u6027\u80be\u810f\u75c5\u60a3\u8005\u63d0\u4f9b\u4e86\u663e\u7740\u7684\u77ed\u671f\u80be\u810f\u4fdd\u62a4\u4f5c\u7528\u3002<\/span><\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"34%E3%80%81%E4%BD%8E%E5%89%82%E9%87%8FADSC%E6%96%B9%E6%A1%88%E6%95%88%E6%9E%9C%E6%9C%80%E4%B8%BA%E7%AA%81%E5%87%BA\"><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">3.4\u3001\u4f4e\u5242\u91cfADSC\u65b9\u6848\u6548\u679c\u6700\u4e3a\u7a81\u51fa<\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e0d\u540c\u5242\u91cfADSC\u6cbb\u7597\u7ec4\u7684\u77ed\u671f\u80be\u529f\u80fd\u53d8\u5316\u8d8b\u52bf\u5b58\u5728\u5dee\u5f02\uff08\u56fe5\uff09\u3002\u4e0e\u771f\u5b9e\u4e16\u754c\u6570\u636e\u5916\u90e8\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0c\u53ea\u6709\u4f4e\u5242\u91cfADSC\u6cbb\u7597\u7ec4\uff086.4\u00d710\u2077\u4e2a\u7ec6\u80de\uff09\u663e\u793a\u51fa\u660e\u786e\u7684\u80be\u810f\u4fdd\u62a4\u4f5c\u7528\uff1a\u5176\u5e73\u5747\u4f30\u7b97\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\u4fdd\u6301\u7a33\u5b9a\uff0c\u800c\u5bf9\u7167\u7ec4\u5219\u5448\u8fdb\u884c\u6027\u4e0b\u964d\uff1b\u4e14\u5176eGFR\u76f8\u5bf9\u4e8e\u57fa\u7ebf\u7684\u767e\u5206\u6bd4\u53d8\u5316\u6301\u7eed\u4fdd\u6301\u4e0a\u5347\u8d8b\u52bf\u3002<\/span><\/span><\/p>\n<section>\n<div id=\"attachment_20751\" style=\"width: 2122px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20751\" class=\"wp-image-20751 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0005-m-scaled.jpg\" alt=\"\" width=\"2112\" height=\"2560\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0005-m-scaled.jpg 2112w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0005-m-247x300.jpg 247w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0005-m-845x1024.jpg 845w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0005-m-768x931.jpg 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0005-m-1267x1536.jpg 1267w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0005-m-1689x2048.jpg 1689w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0005-m-10x12.jpg 10w\" sizes=\"(max-width: 2112px) 100vw, 2112px\" \/><p id=\"caption-attachment-20751\" class=\"wp-caption-text\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u56fe5\uff1a\u6bd4\u8f83ADSC\u6cbb\u7597\u5242\u91cf\u7ec4\u548cRWD\u5bf9\u7167\u7ec4\u7684eGFR\u8d8b\u52bf\u548c\u968f\u65f6\u95f4\u53d8\u5316\u7684\u767e\u5206\u6bd4\u3002<\/span><\/span><\/p><\/div>\n<\/section>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u4e2d\u5242\u91cf\u7ec4\uff0819.2\u00d710\u2077\u4e2a\u7ec6\u80de\uff09\u4e0e\u5bf9\u7167\u7ec4\u7684eGFR\u53d8\u5316\u8f68\u8ff9\u76f8\u4f3c\uff0c\u9ad8\u5242\u91cf\u7ec4\uff0832.0\u00d710\u2077\u4e2a\u7ec6\u80de\uff09\u7684\u7a33\u5b9a\u6027\u867d\u7565\u9ad8\uff0c\u4f46\u5747\u65e0\u7edf\u8ba1\u5b66\u663e\u7740\u5dee\u5f02\u3002<\/span><\/span><span data-pm-slice=\"0 0 []\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u603b\u4f53\u800c\u8a00\uff0c\u8fd9\u4e9b\u7ed3\u679c\u8868\u660e\uff0c\u4e0e\u5176\u4ed6\u5242\u91cf\u7ec4\u76f8\u6bd4\uff0c<\/span><\/span><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4f4e\u5242\u91cf\u6cbb\u7597\u5728\u7a33\u5b9a\u77ed\u671f\u80be\u529f\u80fd\u65b9\u9762\u6548\u679c\u6700\u4e3a\u7a81\u51fa\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5728\u5ef6\u7f13\u80be\u529f\u80fd\u6076\u5316\u8fdb\u7a0b\u65b9\u9762\uff0c\u4f4e\u5242\u91cfADSC\u6cbb\u7597\u4e5f\u5c55\u73b0\u51fa\u663e\u7740\u4f18\u52bf\uff08\u56fe6\uff09\u3002\u751f\u5b58\u5206\u6790\u663e\u793a\uff0c\u4f4e\u5242\u91cfADSC\u6cbb\u7597\u7ec4\u5728\u6240\u6709eGFR\u4e0b\u964d\u9608\u503c\u4e0b\uff0c\u80be\u529f\u80fd\u6076\u5316\u7684\u7d2f\u79ef\u98ce\u9669\u4e0a\u5347\u901f\u5ea6\u5747\u6162\u4e8e\u5bf9\u7167\u7ec4\uff0c\u5176\u4e2deGFR\u4e0b\u964d\u8d85\u8fc730%\u548c35%\u7684\u98ce\u9669\u663e\u7740\u964d\u4f4e\u3002<\/span><\/span><\/p>\n<section>\n<div id=\"attachment_20750\" style=\"width: 1837px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20750\" class=\"wp-image-20750 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0006-m-scaled.jpg\" alt=\"\" width=\"1827\" height=\"2560\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0006-m-scaled.jpg 1827w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0006-m-214x300.jpg 214w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0006-m-731x1024.jpg 731w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0006-m-768x1076.jpg 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0006-m-1096x1536.jpg 1096w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0006-m-1462x2048.jpg 1462w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/cts70415-fig-0006-m-9x12.jpg 9w\" sizes=\"(max-width: 1827px) 100vw, 1827px\" \/><p id=\"caption-attachment-20750\" class=\"wp-caption-text\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u56fe6\uff1a\u672c\u7814\u7a76\u5bf9\u4e0d\u540c\u5242\u91cfADSC\u6cbb\u7597\u7ec4\u548cRWD\u5bf9\u7167\u7ec4\u7684\u80be\u529f\u80fd\u4e0b\u964d\u7d2f\u79ef\u98ce\u9669\u8fdb\u884c\u4e86\u5206\u6790\u3002<\/span><\/span><\/p><\/div>\n<\/section>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u800c\u4e2d\u3001\u9ad8\u5242\u91cf\u6cbb\u7597\u7ec4\u5728\u5927\u591a\u6570\u9608\u503c\uff08\u5982eGFR\u4e0b\u964d20%\u300125%\u300130%\u300135%\uff09\u4e0b\uff0c\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\u5747\u672a\u89c2\u5bdf\u5230\u98ce\u9669\u7d2f\u79ef\u901f\u5ea6\u7684\u663e\u7740\u5dee\u5f02\u3002\u8fd9\u8fdb\u4e00\u6b65\u8bc1\u5b9e\uff0c\u4f4e\u5242\u91cfADSC\u6cbb\u7597\u4e0e\u66f4\u9ad8\u7684\u77ed\u671f\u80be\u529f\u80fd\u7a33\u5b9a\u6027\u76f8\u5173\uff0c\u5176\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\u7684\u6548\u679c\u4f18\u4e8e\u4e2d\u3001\u9ad8\u5242\u91cf\u3002<\/span><\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E5%9B%9B%E3%80%81_%E8%AE%A8%E8%AE%BA%E4%B8%8E%E7%BB%93%E8%AE%BA%EF%BC%9A%E6%84%8F%E4%B9%89%E3%80%81%E5%90%AF%E7%A4%BA%E4%B8%8E%E6%9C%AA%E6%9D%A5%E6%96%B9%E5%90%91\"><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u56db\u3001 \u8ba8\u8bba\u4e0e\u7ed3\u8bba\uff1a\u610f\u4e49\u3001\u542f\u793a\u4e0e\u672a\u6765\u65b9\u5411<\/span><\/span><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"41%E3%80%81%E7%A0%94%E7%A9%B6%E8%AE%BE%E8%AE%A1%E7%9A%84%E7%A7%91%E5%AD%A6%E4%BB%B7%E5%80%BC\"><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4.1\u3001\u7814\u7a76\u8bbe\u8ba1\u7684\u79d1\u5b66\u4ef7\u503c<\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u672c\u7814\u7a76\u901a\u8fc7\u521b\u65b0\u6027\u6574\u5408RWD\u6784\u5efa\u9ad8\u8d28\u91cf\u5916\u90e8\u5bf9\u7167\uff0c\u6210\u529f\u514b\u670d\u4e86\u5355\u81c2\u8bd5\u9a8c\u7f3a\u4e4f\u5bf9\u7167\u7684\u56fa\u6709\u7f3a\u9677\uff0c\u4e3a\u5728\u771f\u5b9e\u4e16\u754c\u80cc\u666f\u4e0b\u4e25\u8c28\u8bc4\u4f30\u7ec6\u80de\u7597\u6cd5\u7597\u6548\u63d0\u4f9b\u4e86\u53ef\u590d\u5236\u7684\u8303\u4f8b\uff0c\u589e\u5f3a\u4e86\u8bc1\u636e\u7684\u53ef\u9760\u6027\u4e0e\u5916\u63a8\u6027\u3002<\/span><\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"42%E3%80%81%E7%9F%AD%E6%9C%9F%E7%96%97%E6%95%88%E7%9A%84%E4%B8%B4%E5%BA%8A%E4%BB%B7%E5%80%BC%E4%B8%8E%E9%95%BF%E6%9C%9F%E5%B1%95%E6%9C%9B\"><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4.2\u3001\u77ed\u671f\u7597\u6548\u7684\u4e34\u5e8a\u4ef7\u503c\u4e0e\u957f\u671f\u5c55\u671b<\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c3d\u7ba1\u89c2\u5bdf\u671f\u4e3a48\u5468\uff0c\u4f46\u7814\u7a76\u4e2d\u89c2\u5bdf\u5230\u7684\u80be\u529f\u80fd\u7a33\u5b9a\u5177\u6709\u91cd\u8981\u4e34\u5e8a\u610f\u4e49\u3002\u5bf9\u4e8e\u4e2d\u665a\u671fCKD\u60a3\u8005\uff0c\u5373\u4f7f\u662f\u77ed\u6682\u7684\u80be\u529f\u80fd\u4e0b\u964d\u4e5f\u4e0e\u900f\u6790\u3001\u7ec8\u672b\u671f\u80be\u75c5\u53ca\u6b7b\u4ea1\u98ce\u9669\u589e\u52a0\u5bc6\u5207\u76f8\u5173\u3002\u56e0\u6b64\uff0c\u572848\u5468\u5185\u7ef4\u6301eGFR\u7a33\u5b9a\u610f\u5473\u7740\u6709\u6548\u7684\u75be\u75c5\u63a7\u5236\u3002\u8fd9\u53ef\u80fd\u662fADSC\u901a\u8fc7\u518d\u751f\u4e0e\u514d\u75ab\u8c03\u8282\u673a\u5236\u542f\u52a8\u80be\u810f\u4fee\u590d\u8fc7\u7a0b\u7684\u65e9\u671f\u4fe1\u53f7\uff0c\u4e3a\u6539\u5584\u957f\u671f\u9884\u540e\u5960\u5b9a\u4e86\u57fa\u7840\uff0c\u4f46\u6b64\u6548\u679c\u9700\u672a\u6765\u66f4\u957f\u65f6\u95f4\u7684\u968f\u8bbf\u7814\u7a76\u6765\u6700\u7ec8\u8bc1\u5b9e\u3002<\/span><\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"43%E3%80%81%E5%89%82%E9%87%8F-%E5%8F%8D%E5%BA%94%E5%85%B3%E7%B3%BB%E7%9A%84%E6%84%8F%E5%A4%96%E5%8F%91%E7%8E%B0%E4%B8%8E%E6%9C%BA%E5%88%B6%E6%8E%A2%E8%AE%A8\"><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4.3\u3001\u5242\u91cf-\u53cd\u5e94\u5173\u7cfb\u7684\u610f\u5916\u53d1\u73b0\u4e0e\u673a\u5236\u63a2\u8ba8<\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u7597\u6548\u4e0e\u5242\u91cf\u5e76\u975e\u7b80\u5355\u7684\u7ebf\u6027\u5173\u7cfb\u3002\u4f4e\u5242\u91cfADSC\uff086.4\u00d710\u2077\u4e2a\u7ec6\u80de\uff09\u8868\u73b0\u51fa\u6700\u4f73\u7684\u80be\u529f\u80fd\u7a33\u5b9a\u6548\u679c\uff0c\u800c\u4e2d\u3001\u9ad8\u5242\u91cf\u7ec4\u7684\u6548\u679c\u76f8\u5bf9\u4e0d\u663e\u7740\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8fd9\u4e00\u73b0\u8c61\u4e0e\u67d0\u4e9b\u540c\u7c7b\u7814\u7a76\u7ed3\u8bba\u4e00\u81f4\uff0c\u53ef\u80fd\u7684\u539f\u56e0\u5305\u62ec\uff1aADSC\u4e3b\u8981\u901a\u8fc7\u65c1\u5206\u6ccc\u4fe1\u53f7\u6fc0\u6d3b\u673a\u4f53\u81ea\u8eab\u4fee\u590d\u7cfb\u7edf\uff0c\u800c\u975e\u76f4\u63a5\u66ff\u4ee3\u53d7\u635f\u7ec6\u80de\uff1b\u8fc7\u9ad8\u7684\u5242\u91cf\u53ef\u80fd\u5f15\u53d1\u4e0d\u5fc5\u8981\u7684\u514d\u75ab\u6216\u708e\u75c7\u53cd\u5e94\uff0c\u62b5\u6d88\u5176\u4fdd\u62a4\u4f5c\u7528\u3002\u8fd9\u4e00\u53d1\u73b0\u63d0\u793a\uff0c\u786e\u5b9a\u4e00\u4e2a\u80fd\u591f\u5145\u5206\u6fc0\u6d3b\u4fee\u590d\u53cd\u5e94\u3001\u517c\u5177\u5b89\u5168\u6027\u4e0e\u6210\u672c\u6548\u76ca\u7684\u201c\u6cbb\u7597\u7a97\u53e3\u201d\u81f3\u5173\u91cd\u8981\u3002<\/span><\/span><\/p>\n<h3><span class=\"ez-toc-section\" id=\"44%E3%80%81%E7%BB%BC%E5%90%88%E7%BB%93%E8%AE%BA%E4%B8%8E%E6%9C%AA%E6%9D%A5%E5%B1%95%E6%9C%9B\"><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4.4\u3001\u7efc\u5408\u7ed3\u8bba\u4e0e\u672a\u6765\u5c55\u671b<\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7efc\u4e0a\u6240\u8ff0\uff0c\u5f02\u4f53\u8102\u80aa\u6765\u6e90\u5e72\u7ec6\u80de\uff08ADSC\uff09\u7597\u6cd5\uff0c\u7279\u522b\u662f\u4f4e\u5242\u91cf\u65b9\u6848\uff0c\u5728\u77ed\u671f\u5185\u80fd\u663e\u7740\u7a33\u5b9a\u665a\u671fCKD\u60a3\u8005\u7684\u80be\u529f\u80fd\uff0c\u5e76\u5927\u5e45\u964d\u4f4e\u80be\u529f\u80fd\u6076\u5316\u98ce\u9669\uff0c\u4e14\u5728\u6240\u6709\u5242\u91cf\u4e0b\u5747\u8868\u73b0\u51fa\u826f\u597d\u7684\u5b89\u5168\u6027\u4e0e\u8010\u53d7\u6027\u3002\u5176\u4f5c\u7528\u673a\u5236\u53ef\u80fd\u8d85\u8d8a\u4f20\u7edf\u836f\u7269\uff0c\u76f4\u6307\u80be\u810f\u635f\u4f24\u4fee\u590d\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u672a\u6765\u9700\u8981\u5f00\u5c55\u66f4\u5927\u89c4\u6a21\u3001\u66f4\u957f\u968f\u8bbf\u671f\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u9a8c\u8bc1\u957f\u671f\u7597\u6548\uff0c\u5e76\u8fdb\u4e00\u6b65\u9610\u660e\u5176\u751f\u7269\u5b66\u673a\u5236\uff0c\u4f18\u5316\u6cbb\u7597\u7b56\u7565\uff0c\u6700\u7ec8\u63a8\u52a8\u8fd9\u4e00\u6709\u524d\u666f\u7684\u7597\u6cd5\u60e0\u53ca\u5e7f\u5927\u60a3\u8005\u3002<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<blockquote>\n<p data-pm-slice=\"0 0 []\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">References:<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[1] <\/span><\/span><span data-pm-slice=\"0 0 []\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Y.-C. Lin<\/span><\/span><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u3001Y.-P. Hung\u3001Y.-C. Tian \u7b49\uff0c\u201c\u771f\u5b9e\u4e16\u754c\u6570\u636e\u4f5c\u4e3a\u5916\u90e8\u5bf9\u7167\u8bc4\u4f30\u540c\u79cd\u5f02\u4f53\u8102\u80aa\u5e72\u7ec6\u80de\u7597\u6cd5\u6cbb\u7597\u665a\u671f\u6162\u6027\u80be\u75c5\u7684\u7597\u6548\u201d\uff0c\u00a0<\/span><\/span><i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e34\u5e8a\u4e0e\u8f6c\u5316\u79d1\u5b66<\/span><\/span><\/i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u00a018\uff0c\u7b2c 12 \u671f\uff082025\uff09\uff1ae70415\uff0chttps:\/\/doi.org\/10.1111\/cts.70415\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Disclaimer: This article is intended only to disseminate scientific knowledge and share industry perspectives, and does not constitute any clinical diagnostic advice! The information published by Hangi Stem Cells is not a substitute for the professional advice of a physician or pharmacist. If you have any questions about copyright or other issues, please feel free to contact me.<\/span><\/span><\/p><\/blockquote>","protected":false},"excerpt":{"rendered":"<p>\u6162\u6027\u80be\u810f\u75c5\uff08CKD\uff09\u662f\u4e00\u79cd\u8fdb\u884c\u6027\u75be\u75c5\uff0c\u665a\u671f\u60a3\u8005\u6cbb\u7597\u9009\u62e9\u6709\u9650\uff0c\u9884\u540e\u4e0d\u4f73\u3002\u8fd1\u5e74\u6765\uff0c\u8102\u80aa\u6765\u6e90\u5e72\u7ec6\u80de\uff08ADSC\uff09\u7597\u6cd5\u56e0 [&hellip;]<\/p>","protected":false},"author":1,"featured_media":20749,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[76,84],"tags":[220,249,248],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20748"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/comments?post=20748"}],"version-history":[{"count":1,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20748\/revisions"}],"predecessor-version":[{"id":20757,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20748\/revisions\/20757"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media\/20749"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media?parent=20748"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/categories?post=20748"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/tags?post=20748"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}