{"id":20946,"date":"2025-12-16T14:50:21","date_gmt":"2025-12-16T06:50:21","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=20946"},"modified":"2025-12-16T14:50:49","modified_gmt":"2025-12-16T06:50:49","slug":"https-www-hjtdsm-cn-stem-cells-stem-cell-therapy-20946-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20946.html","title":{"rendered":"\u5e72\u7ec6\u80de\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff1a\u5386\u53f2\u6f14\u53d8\u3001\u5f53\u524d\u8fdb\u5c55\u4e0e\u672a\u6765\u5c55\u671b"},"content":{"rendered":"<section data-role=\"outer\" data-pm-slice=\"0 0 []\">\n<section data-role=\"paragraph\">\u81ea\u8eab\u514d\u75ab\u75c5\uff08AD\uff09\u662f\u4e00\u7c7b\u4ee5\u514d\u75ab\u7cfb\u7edf\u5f02\u5e38\u653b\u51fb\u81ea\u8eab\u7ec4\u7ec7\u4e3a\u7279\u5f81\u7684\u590d\u6742\u75be\u75c5\uff0c\u5168\u7403\u60a3\u8005\u6570\u91cf\u5e9e\u5927\u4e14\u6cbb\u7597\u9700\u6c42\u8feb\u5207\u3002\u4f20\u7edf\u7597\u6cd5\u5982\u7cd6\u76ae\u8d28\u6fc0\u7d20\u548c\u514d\u75ab\u6291\u5236\u5242\u867d\u80fd\u7f13\u89e3\u75c7\u72b6\uff0c\u4f46\u5b58\u5728\u611f\u67d3\u3001\u4ee3\u8c22\u5f02\u5e38\u3001\u9aa8\u8d28\u758f\u677e\u7b49\u591a\u79cd\u4e0d\u826f\u53cd\u5e94\uff0c\u4e14\u7ea630%~40%\u7684\u60a3\u8005\u7597\u6548\u4e0d\u4f73\u3002\u56e0\u6b64\uff0c\u4e34\u5e8a\u4e9f\u9700\u80fd\u4ece\u6839\u672c\u4e0a\u8c03\u8282\u514d\u75ab\u3001\u5b9e\u73b0\u957f\u671f\u7f13\u89e3\u7684\u65b0\u7597\u6cd5\u3002<\/p>\n<section><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-20950 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-2216693974-612x612-1.jpg\" alt=\"\u5e72\u7ec6\u80de\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff1a\u5386\u53f2\u6f14\u53d8\u3001\u5f53\u524d\u8fdb\u5c55\u4e0e\u672a\u6765\u5c55\u671b\" width=\"612\" height=\"344\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-2216693974-612x612-1.jpg 612w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-2216693974-612x612-1-300x169.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/istockphoto-2216693974-612x612-1-18x10.jpg 18w\" sizes=\"(max-width: 612px) 100vw, 612px\" \/><\/section>\n<p>\u8fd1\u5e74\u6765\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u4f5c\u4e3a\u4e00\u79cd\u65b0\u5174\u6cbb\u7597\u7b56\u7565\uff0c\u4e3aAD\u6cbb\u7597\u5e26\u6765\u4e86\u65b0\u7684\u5e0c\u671b[1]\u3002\u5176\u4e2d\uff0c<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-transplantation\/19749.html\/\" target=\"_blank\" rel=\"noopener\">\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\uff08HSCT\uff09<\/a>\u4e0e\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\uff08MSCT\uff09\u5728\u96be\u6cbb\u6027AD\u4e2d\u5c55\u73b0\u51fa\u72ec\u7279\u6f5c\u529b\uff0c\u4f46\u5176\u673a\u5236\u3001\u7597\u6548\u5f02\u8d28\u6027\u53ca\u6cbb\u7597\u65b9\u6848\u4f18\u5316\u7b49\u95ee\u9898\u4ecd\u5f85\u6df1\u5165\u63a2\u7d22\u3002\u672c\u6587\u7cfb\u7edf\u56de\u987e\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u6f14\u53d8\u5386\u7a0b\uff0c\u603b\u7ed3\u73b0\u6709\u7ecf\u9a8c\u4e0e\u6311\u6218\uff0c\u5e76\u5c55\u671b\u5176\u672a\u6765\u53d1\u5c55\u65b9\u5411\uff0c\u4ee5\u671f\u4e3a\u4e34\u5e8a\u8f6c\u5316\u4e0e\u7cbe\u51c6\u533b\u7597\u63d0\u4f9b\u53c2\u8003\u3002<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20946.html\/#%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%87%AA%E8%BA%AB%E5%85%8D%E7%96%AB%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E8%B5%B7%E6%BA%90\" >\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u8d77\u6e90<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20946.html\/#%E9%80%A0%E8%A1%80%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%87%AA%E8%BA%AB%E5%85%8D%E7%96%AB%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E7%BB%8F%E9%AA%8C%E6%95%99%E8%AE%AD\" >\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u7ecf\u9a8c\u6559\u8bad<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20946.html\/#%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88MSC%EF%BC%89%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%87%AA%E8%BA%AB%E5%85%8D%E7%96%AB%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E7%A0%94%E7%A9%B6%E8%BF%9B%E5%B1%95\" >\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u7814\u7a76\u8fdb\u5c55<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20946.html\/#%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%87%AA%E8%BA%AB%E5%85%8D%E7%96%AB%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E2%80%9C%E6%98%AF%E4%B8%8E%E9%9D%9E%E2%80%9D\" >\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u201c\u662f\u4e0e\u975e\u201d<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20946.html\/#%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97AD%E7%9A%84%E6%80%9D%E8%80%83\" >\u5e72\u7ec6\u80de\u6cbb\u7597AD\u7684\u601d\u8003<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20946.html\/#%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97AD%E7%9A%84%E5%8F%91%E5%B1%95%E8%B6%8B%E5%8A%BF\" >\u5e72\u7ec6\u80de\u6cbb\u7597AD\u7684\u53d1\u5c55\u8d8b\u52bf<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20946.html\/#%E6%80%BB%E7%BB%93%E4%B8%8E%E5%B1%95%E6%9C%9B\" >Summary and outlook<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%87%AA%E8%BA%AB%E5%85%8D%E7%96%AB%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E8%B5%B7%E6%BA%90\"><\/span><strong>\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u8d77\u6e90<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u6211\u56fdAD\u60a3\u8005\u4f30\u8ba1\u7ea68000\u4e07\uff0c\u4f20\u7edf\u4ee5\u7cd6\u76ae\u8d28\u6fc0\u7d20\u548c\u514d\u75ab\u6291\u5236\u5242\u4e3a\u4e3b\u8981\u6cbb\u7597\u624b\u6bb5\u3002\u8fd1\u5e74\u6765\uff0c\u751f\u7269\u5236\u5242\u4e0e\u5c0f\u5206\u5b50\u836f\u7269\u867d\u53d6\u5f97\u663e\u8457\u8fdb\u5c55\uff0c\u4f46\u4ecd\u6709\u90e8\u5206\u60a3\u8005\u7597\u6548\u6b20\u4f73\uff0c\u4e14\u957f\u671f\u7528\u836f\u4f34\u968f\u4e00\u7cfb\u5217\u4e0d\u826f\u53cd\u5e94\u3002\u56e0\u6b64\uff0c\u73b0\u6709\u836f\u7269\u6cbb\u7597\u591a\u4ec5\u80fd\u63a7\u5236\u75c7\u72b6\uff0c\u96be\u4ee5\u5b9e\u73b0\u201c\u6807\u672c\u517c\u6cbb\u201d\u3002<\/p>\n<p>\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u8bbe\u60f3\u53ef\u8ffd\u6eaf\u81f320\u4e16\u7eaa70\u5e74\u4ee3\u3002\u5f53\u65f6\u6709\u6b27\u6d32\u5b66\u8005\u62a5\u9053\uff0c4\u4f8b\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u60a3\u8005\u5728\u56e0\u91d1\u5236\u5242\u5bfc\u81f4\u91cd\u578b\u518d\u751f\u969c\u788d\u6027\u8d2b\u8840\u540e\uff0c\u63a5\u53d7\u5f02\u57fa\u56e0\u9aa8\u9ad3\u79fb\u690d\uff0c\u4e0d\u4ec5\u8d2b\u8840\u7f13\u89e3\uff0c\u5173\u8282\u708e\u4e5f\u83b7\u5f97\u4e0d\u540c\u7a0b\u5ea6\u6539\u5584\uff0c\u5176\u4e2d1\u4f8b\u5b9e\u73b0\u957f\u671f\u7f13\u89e3\u3002\u8fd9\u4e00\u5076\u7136\u53d1\u73b0\u63d0\u793a\uff0c\u91cd\u5efa\u514d\u75ab\u7cfb\u7edf\u53ef\u80fd\u5bf9AD\u5177\u6709\u6cbb\u7597\u4f5c\u7528\u3002<\/p>\n<p>1993\u5e74\uff0c\u610f\u5927\u5229Marmont\u6559\u6388\u9996\u6b21\u660e\u786e\u63d0\u51fa\u5229\u7528\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684\u8bbe\u60f3\u3002<\/p>\n<p>1997\u5e74\uff0c\u8be5\u56e2\u961f\u6210\u529f\u5e94\u7528\u81ea\u4f53\u9aa8\u9ad3HSCT\u6cbb\u75971\u4f8bSLE\u60a3\u8005\uff0c\u7531\u6b64\u5f00\u542f\u4e86\u5e72\u7ec6\u80de\u6cbb\u7597AD\u7684\u65b0\u7bc7\u7ae0\u3002\u8fc4\u4eca\uff0c\u5168\u7403\u5df2\u6709\u8d85\u8fc74000\u4f8b\u96be\u6cbb\u6027AD\u60a3\u8005\u63a5\u53d7HSCT\u6cbb\u7597\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E9%80%A0%E8%A1%80%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%87%AA%E8%BA%AB%E5%85%8D%E7%96%AB%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E7%BB%8F%E9%AA%8C%E6%95%99%E8%AE%AD\"><\/span><strong>\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u7ecf\u9a8c\u6559\u8bad<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>HSCT\u6cbb\u7597AD\u7edd\u5927\u90e8\u5206\u7528\u81ea\u4f53\u9020\u8840\u5e72\u7ec6\u80de\uff0c\u5f02\u4f53HSCT\u6392\u5f02\u53cd\u5e94\u548c\u9ad8\u6b7b\u4ea1\u7387\uff0830%~50%\uff09\u9650\u5236\u4e86\u5176\u4f7f\u7528\u3002\u56de\u987e\u5e72\u7ec6\u80de\u6cbb\u7597AD\u8fd130\u5e74\u7814\u7a76\u5386\u7a0b\uff0c\u4e3b\u8981\u542f\u793a\u5982\u4e0b\uff1a<\/p>\n<ul class=\"list-paddingleft-1\">\n<li>\u2460\u5c3d\u7ba1HSCT\u6cbb\u7597\u96be\u6cbb\u6027AD\u663e\u793a\u51fa\u4e00\u5b9a\u7597\u6548\uff0c\u4f46\u590d\u53d1\u95ee\u9898\u4f9d\u7136\u5b58\u5728\uff0c\u7814\u7a76\u6570\u636e\u663e\u793a\uff0c1\u5e74\u590d\u53d1\u7387\u7ea6\u4e3a40%\uff1b<\/li>\n<li>\u2461\u6e05\u9ad3\u9884\u5904\u7406\uff08\u767d\u7ec6\u80de\u964d\u81f30\uff09\u7684\u5e76\u53d1\u75c7\u53d1\u751f\u7387\u9ad8\uff0c\u79fb\u690d\u76f8\u5173\u6b7b\u4ea1\u7387\u9ad8\uff082%~17%\uff09\uff0c\u611f\u67d3\u662f\u4e3b\u8981\u6b7b\u4ea1\u539f\u56e0\uff1b<\/li>\n<li>\u2462\u975e\u6e05\u9ad3\u9884\u5904\u7406\u53ef\u663e\u8457\u964d\u4f4e\u5e76\u53d1\u75c7\u53d1\u751f\u7387\u548c\u6b7b\u4ea1\u7387\uff1b<\/li>\n<li>\u2463\u9ad8\u5f3a\u5ea6\u514d\u75ab\u6291\u5236\uff08\u4ee5\u73af\u78f7\u9170\u80fa\u4e3a\u4e3b\uff09\u8054\u5408\u81ea\u4f53HSCT\u6cbb\u7597\u65e9\u671f\u65e0\u5fc3\u80ba\u75be\u75c5\u8fdb\u5c55\u3001\u9884\u540e\u5dee\u7684\u5f25\u6f2b\u6027\u7cfb\u7edf\u6027\u786c\u5316\u75c5\uff08dcSSc\uff09\u5df2\u88ab\u7eb3\u51652023\u5e74EULAR\u7cfb\u7edf\u6027\u786c\u5316\u75c5\uff08SSc\uff09\u6cbb\u7597\u63a8\u8350\uff1b<\/li>\n<li>\u2464\u975e\u6e05\u9ad3\u6027\u73af\u78f7\u9170\u80fa\u6cbb\u7597\u4e0d\u8054\u5408\u81ea\u4f53HSCT\u5bf9\u90e8\u5206AD\u60a3\u8005\uff08\u5982\u72fc\u75ae\u80be\u708e\uff09\u4e5f\u5177\u6709\u4e00\u5b9a\u7684\u7597\u6548\uff1b<\/li>\n<li>\u2465HSCT\u6cbb\u7597AD\u7684\u673a\u5236\u4e3b\u8981\u662f\u79fb\u690d\u9884\u5904\u7406\u65b9\u6848\u4e2d\u5927\u5242\u91cf\u653e\u5316\u7597\u7684\u514d\u75ab\u6e05\u9664\uff0cT\u7ec6\u80de\u3001B\u7ec6\u80de\u518d\u751f\u8fc7\u7a0b\u4e2d\u8bf1\u5bfc\u514d\u75ab\u8010\u53d7\uff0c\u514d\u75ab\u91cd\u5efa\u8fc7\u7a0b\u4e2d\u8fbe\u5230\u65b0\u7684\u514d\u75ab\u5e73\u8861\u3002<\/li>\n<\/ul>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c\u81ea\u4f53\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u5bf9\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u5177\u6709\u4e00\u5b9a\u7597\u6548\uff0c\u4f46\u7531\u4e8e\u8d39\u7528\u9ad8\u3001\u5e76\u53d1\u75c7\u53d1\u751f\u7387\u9ad8\u3001\u6b7b\u4ea1\u7387\u9ad8\u3001\u6240\u9700\u6761\u4ef6\u9ad8\uff08\u5c42\u6d41\u75c5\u623f\uff09\uff0c\u96be\u4ee5\u5728\u4e34\u5e8a\u5e38\u89c4\u5f00\u5c55\uff0c\u65e0\u6cd5\u6ee1\u8db3\u4e34\u5e8a\u9700\u6c42\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88MSC%EF%BC%89%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%87%AA%E8%BA%AB%E5%85%8D%E7%96%AB%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E7%A0%94%E7%A9%B6%E8%BF%9B%E5%B1%95\"><\/span><strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u7814\u7a76\u8fdb\u5c55<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u662f\u9aa8\u9ad3\u4e2d\u5b58\u5728\u7684\u53e6\u4e00\u7c7b\u57fa\u8d28\u7ec6\u80de\u30022007\u5e74\u9996\u6b21\u5e94\u7528\u5f02\u4f53\u9aa8\u9ad3MSC\u79fb\u690d\uff08MSCT\uff09\u6cbb\u7597\u96be\u6cbb\u6027SLE\uff0c\u53d6\u5f97\u8f83\u597d\u7597\u6548\u3002<\/p>\n<p>2022\u5e74\uff0c\u77e5\u540d\u671f\u520a\u6742\u5fd7\u300a\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u300b\u520a\u53d1\u4e86\u4e00\u7bc7<a href=\"https:\/\/link.springer.com\/article\/10.1186\/s13287-022-02782-7#citeas\" target=\"_blank\" rel=\"noopener nofollow\">\u201c\u805a\u7126\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u5728\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u4e2d\u7684\u4e34\u5e8a\u5e94\u7528\u201d<\/a>\u7684\u7814\u7a76\u7efc\u8ff0\uff0c\u8be5\u7814\u7a76\u7efc\u8ff0\u4e86\u4e0d\u540c\u7c7b\u578bMSCs\u7684\u6700\u65b0\u7814\u7a76\u8fdb\u5c55\u53ca\u5176\u5728\u591a\u79cd\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff08\u5305\u62ec<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20541.html\/\" target=\"_blank\" rel=\"noopener\">\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e<\/a>,<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/20228.html\/\" target=\"_blank\" rel=\"noopener\">1\u578b\u7cd6\u5c3f\u75c5<\/a>\u3001\u591a\u53d1\u6027\u786c\u5316\u75c7\u3001\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u3001\u708e\u75c7\u6027\u80a0\u75c5\u3001\u81ea\u8eab\u514d\u75ab\u6027\u809d\u75c5\u548c\u5e72\u71e5\u7efc\u5408\u5f81\uff09\u4e34\u5e8a\u6cbb\u7597\u4e2d\u7684\u7597\u6548\u548c\u53ef\u884c\u6027[2]\u3002<\/p>\n<section>\n<div id=\"attachment_20949\" style=\"width: 763px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-20949\" class=\"wp-image-20949 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134519_626.png\" alt=\"\" width=\"753\" height=\"439\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134519_626.png 753w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134519_626-300x175.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134519_626-18x10.png 18w\" sizes=\"(max-width: 753px) 100vw, 753px\" \/><p id=\"caption-attachment-20949\" class=\"wp-caption-text\">\u805a\u7126\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u5728\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u4e2d\u7684\u4e34\u5e8a\u5e94\u7528<\/p><\/div>\n<\/section>\n<\/section>\n<section data-role=\"paragraph\">\u8be5\u6587\u6307\u51fa\uff0cMSC\u56e0\u5176\u6613\u4e8e\u83b7\u53d6\u3001\u6269\u589e\u80fd\u529b\u5f3a\u3001\u5177\u6709\u591a\u5411\u5206\u5316\u6f5c\u80fd\u53ca\u663e\u8457\u7684\u6297\u708e\u3001\u514d\u75ab\u8c03\u8282\u548c\u7ec4\u7ec7\u4fee\u590d\u80fd\u529b\uff0c\u5728AD\u6cbb\u7597\u4e2d\u5c55\u73b0\u51fa\u5e7f\u9614\u524d\u666f\u3002\u6b64\u5916\uff0cMSC\u514d\u75ab\u539f\u6027\u4f4e\u3001\u81f4\u7624\u98ce\u9669\u5c0f\uff0c\u66f4\u9002\u5408\u4e34\u5e8a\u8f6c\u5316\u3002\u591a\u6570\u7814\u7a76\u91c7\u7528\u9759\u8109\u8f93\u6ce8\uff0c\u5242\u91cf\u4e00\u822c\u57281\u00d710\u2076~1\u00d710\u2078 cells\/kg\uff0c\u4e14\u91cd\u590d\u8f93\u6ce8\u5f80\u5f80\u6548\u679c\u66f4\u4f73\u30022024\u5e7412\u6708\uff0c\u8457\u540d\u671f\u520a\u6742\u5fd7\u300a\u514d\u75ab\u6027\u524d\u6cbf\u300b\u53d1\u8868\u4e86\u4e00\u7bc7<a href=\"https:\/\/www.frontiersin.org\/journals\/immunology\/articles\/10.3389\/fimmu.2024.1525380\/full\" target=\"_blank\" rel=\"noopener nofollow\">\u201c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5728\u81ea\u8eab\u708e\u75c7\u6027\u75be\u75c5\u4e2d\u4f5c\u4e3a\u8c03\u8282\u56e0\u5b50\u7684\u6700\u65b0\u7814\u7a76\u8fdb\u5c55\u201d<\/a>\u7684\u7814\u7a76\u7efc\u8ff0[3]\u3002<\/p>\n<section><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-20948 aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134545_194.png\" alt=\"\" width=\"1078\" height=\"449\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134545_194.png 1078w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134545_194-300x125.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134545_194-1024x427.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134545_194-768x320.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134545_194-18x7.png 18w\" sizes=\"(max-width: 1078px) 100vw, 1078px\" \/><\/section>\n<p>\u7efc\u8ff0\u8868\u660e\u4f20\u7edf\u7597\u6cd5\u4e0e\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u7684\u534f\u540c\u8054\u5408\u6cbb\u7597\u662f\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u708e\u75c7\u6027\u75be\u75c5\u7684\u4e00\u79cd\u6781\u5177\u524d\u666f\u7684\u7b56\u7565\u3002\u8fd9\u79cd\u8303\u5f0f\u8f6c\u53d8\u6709\u671b\u63d0\u5347\u6cbb\u7597\u6548\u679c\uff0c\u5e76\u51cf\u8f7b\u8fd9\u4e9b\u75be\u75c5\u7ed9\u60a3\u8005\u5e26\u6765\u7684\u5de8\u5927\u8d1f\u62c5\u3002\u603b\u4f53\u800c\u8a00\uff0cMSCs\u4e3a\u514d\u75ab\u4ecb\u5bfc\u6027\u75be\u75c5\u63d0\u4f9b\u4e86\u6709\u524d\u666f\u7684\u6cbb\u7597\u9009\u62e9\uff0c\u5176\u6f5c\u5728\u673a\u5236\u5305\u62ec\u514d\u75ab\u8c03\u8282\u548c\u8bf1\u5bfc\u514d\u75ab\u8010\u53d7\u3002<\/p>\n<p>2025\u5e747\u6708\uff0c\u300a\u514d\u75ab\u6027\u524d\u6cbf\u300b\u6742\u5fd7\u518d\u6b21\u53d1\u8868\u4e86\u4e00\u7bc7<a class=\"normal_text_link mp_article_text_link\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzkwOTEzMDY0Nw==&amp;mid=2247516074&amp;idx=1&amp;sn=cd8d693235b59ec6b6f597857efa122a&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener nofollow\" data-itemshowtype=\"0\" data-linktype=\"2\">\u201c\u5168\u7403\u5e72\u7ec6\u80de\u7597\u6cd5\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff1a\u8d8b\u52bf\u4e0e\u672a\u6765\u65b9\u5411\u201d<\/a>\u7684\u7814\u7a76\u7efc\u8ff0\u7684\u6587\u7ae0[4]\u3002<\/p>\n<section><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-20947 aligncenter\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134819_427.png\" alt=\"\" width=\"1009\" height=\"547\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134819_427.png 1009w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134819_427-300x163.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134819_427-768x416.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-16_134819_427-18x10.png 18w\" sizes=\"(max-width: 1009px) 100vw, 1009px\" \/><\/section>\n<p>\u8fd9\u9879\u7814\u7a76\u5171\u7eb3\u5165244\u9879\u8bd5\u9a8c\uff0c\u5176\u4e2d83.6%\u5904\u4e8e\u2160\/\u2161\u671f\u3002\u514b\u7f57\u6069\u75c5\u3001SLE\u548c\u786c\u76ae\u75c5\u7814\u7a76\u6700\u591a\uff0c\u4e2d\u7f8e\u4e24\u56fd\u8bd5\u9a8c\u6570\u91cf\u9886\u5148\u3002\u8fd1\u534a\u6570\u8bd5\u9a8c\u7531\u5b66\u672f\u673a\u6784\u8d44\u52a9\uff0c\u4e3b\u8981\u6cbb\u7597\u7b56\u7565\u5305\u62ec\u514d\u75ab\u8c03\u8282\u3001\u7ec4\u7ec7\u4fee\u590d\u53ca\u6297\u611f\u67d3\/\u6297\u589e\u6b96\u7b49\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E7%A7%BB%E6%A4%8D%E6%B2%BB%E7%96%97%E8%87%AA%E8%BA%AB%E5%85%8D%E7%96%AB%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E2%80%9C%E6%98%AF%E4%B8%8E%E9%9D%9E%E2%80%9D\"><\/span><strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u201c\u662f\u4e0e\u975e\u201d<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u7814\u7a76\u53d1\u73b0\uff0c\u4e0e\u9020\u8840\u5e72\u7ec6\u80de\uff08HSC\uff09\u7c7b\u4f3c\uff0cSLE\u60a3\u8005\u6765\u6e90\u7684\u9aa8\u9ad3MSC\u540c\u6837\u5b58\u5728\u529f\u80fd\u5f02\u5e38\uff0c\u81ea\u4f53MSCT\u6cbb\u7597SLE\u6a21\u578b\u9f20\u548c\u60a3\u8005\u65e0\u6548\u3002\u4e0eHSC\u4e0d\u540c\u7684\u662f\uff0c\u5f02\u4f53MSC\u8f93\u6ce8\u65e0\u6392\u5f02\u53cd\u5e94\uff0c\u65e0\u9700\u6297\u6392\u5f02\u6cbb\u7597\u3002<\/p>\n<p>\u6839\u636e\u4ee5\u4e0a\u4e09\u7bc7\u5173\u4e8e\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff1a<\/p>\n<ul class=\"list-paddingleft-1\">\n<li>\u2460\u5f02\u4f53MSCT\uff08\u6cbb\u7597\u65b9\u6848\u4e3a\uff1a\u6309\u4f53\u8d28\u91cf\u8ba1\u7b97\u975e\u9884\u5904\u7406MSC\u7ec6\u80de\u6570\u22651\u00d710\u2076\/kg\uff0c\u4e00\u6b21\u9759\u8109\u8f93\u6ce8\uff09\u5b89\u5168\u6709\u6548\uff0c\u6cbb\u7597SLE\u6709\u6548\u7387\u4e3a60%\uff1b<\/li>\n<li>\u2461\u975e\u6e05\u9ad3\u9884\u5904\u7406\u548c\u975e\u9884\u5904\u7406\u5f02\u4f53MSCT\u7597\u6548\u76f8\u5f53\uff1b<\/li>\n<li>\u2462\u5f02\u4f53MSCT\u65e0\u4e25\u91cd\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\uff0c\u65e0\u79fb\u690d\u76f8\u5173\u6b7b\u4ea1\uff1b<\/li>\n<li>\u2463\u5f02\u4f53MSCT\u5bf9AD\u4f34\u53d1\u7684\u5176\u4ed6\u75c5\u53d8\uff0c\u5982\u7cd6\u76ae\u8d28\u6fc0\u7d20\u76f8\u5173\u7684\u9ad8\u8102\u8840\u75c7\u3001\u9ad8\u8840\u7cd6\u3001\u9aa8\u8d28\u758f\u677e\u7b49\uff0c\u4e5f\u6709\u4e00\u5b9a\u7684\u6cbb\u7597\u4f5c\u7528\uff1b<\/li>\n<li>\u2464\u5f02\u4f53MSCT\u5bf9SLE\u7b49AD\u5e76\u53d1\u7684\u611f\u67d3\u5177\u6709\u663e\u8457\u7684\u6297\u611f\u67d3\u4f5c\u7528\uff1b<\/li>\n<li>\u2465\u5f02\u4f53MSCT\u5177\u6709\u5f3a\u5927\u7684\u7ec4\u7ec7\u4fee\u590d\u80fd\u529b\uff0c\u53ef\u7528\u4e8e\u6cbb\u7597\u5927\u9762\u79ef\u96be\u6cbb\u6027\u76ae\u80a4\u6e83\u75a1\u3001\u5265\u8131\u6027\u76ae\u708e\u548c\u708e\u6027\u80a0\u75c5\uff08IBD\uff09\u7b49\uff1b<\/li>\n<li>\u2466\u8d39\u7528\u4f4e\u3001\u5e76\u53d1\u75c7\u53d1\u751f\u7387\u4f4e\u3001\u65e0\u9700\u5c42\u6d41\u75c5\u623f\uff0cMSC\u6765\u6e90\u5e7f\u6cdb\uff0c\u4e34\u5e8a\u6613\u63a8\u5e7f\u5e94\u7528\uff0c\u5177\u5907\u6210\u836f\u6027\uff1b<\/li>\n<li>\u2467\u5f02\u4f53MSCT\u6cbb\u7597\u96be\u6cbb\u6027SLE\uff0c\u968f\u8bbf5\u5e74\u6b7b\u4ea1\u7387\u4e0b\u964d29%\uff0c\u4e34\u5e8a\u7f13\u89e3\u738734%\uff0c\u590d\u53d1\u738725%\uff0c\u590d\u53d1\u60a3\u8005\u91cd\u590d\u6cbb\u7597\u4e5f\u6709\u4e00\u5b9a\u7597\u6548\u3002<\/li>\n<\/ul>\n<p>2024\u5e7412\u6708\u81f32025\u5e741\u6708\uff0c\u7f8e\u56fdFDA\u4e0e\u4e2d\u56fdCDE\u76f8\u7ee7\u6279\u51c6\u5f02\u4f53MSC\u4ea7\u54c1\u7528\u4e8e\u6fc0\u7d20\u8010\u836f\u6025\u6027\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\uff0c\u6807\u5fd7\u7740MSC\u7597\u6cd5\u5411\u89c4\u8303\u5316\u3001\u6210\u836f\u5316\u8fc8\u51fa\u5173\u952e\u4e00\u6b65\u3002<\/p>\n<\/section>\n<h2><span class=\"ez-toc-section\" id=\"%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97AD%E7%9A%84%E6%80%9D%E8%80%83\"><\/span><strong>\u5e72\u7ec6\u80de\u6cbb\u7597AD\u7684\u601d\u8003<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u7b2c\u4e00\uff0c\u5e94\u601d\u8003\u5982\u4f55\u9009\u62e9\u5e76\u4f18\u5316\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u6839\u672c\u8def\u5f84\u3002\u7814\u7a76\u63d0\u793a\u81ea\u4f53\u5e72\u7ec6\u80de\uff08\u65e0\u8bba\u662f\u5148\u5929\u7f3a\u9677\u7684HSC\u8fd8\u662f\u540e\u5929\u7f3a\u9677\u7684MSC\uff09\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u75c5\uff08AD\uff09\u7597\u6548\u6709\u9650\u4e14\u6613\u590d\u53d1\u3002<\/p>\n<p>\u56e0\u6b64\uff0c\u6cbb\u7597\u8def\u5f84\u7684\u9009\u62e9\u96c6\u4e2d\u5728\u5f02\u4f53\u5e72\u7ec6\u80de\u4e0a\uff1a\u5f02\u4f53HSC\u5177\u6709\u4ece\u6839\u672c\u4e0a\u91cd\u5efa\u5065\u5eb7\u514d\u75ab\u7cfb\u7edf\u7684\u5de8\u5927\u6f5c\u529b\uff0c\u4f46\u5176\u4e34\u5e8a\u5e94\u7528\u9762\u4e34\u6392\u5f02\u53cd\u5e94\u548c\u4f53\u5916\u5927\u89c4\u6a21\u6269\u589e\u4e24\u5927\u6280\u672f\u74f6\u9888\uff1b\u800c\u5f02\u4f53MSC\u5219\u56e0\u65e0\u9700\u9884\u5904\u7406\u3001\u65e0\u4e25\u91cd\u6392\u5f02\u53cd\u5e94\u800c\u5df2\u5c55\u73b0\u51fa\u663e\u8457\u7597\u6548\uff0c\u5e76\u5177\u5907\u6210\u836f\u6027\u3002\u672a\u6765\u9700\u653b\u514b\u5f02\u4f53HSC\u7684\u6280\u672f\u96be\u9898\uff0c\u5e76\u660e\u786e\u5f02\u4f53MSC\u4e0e\u81ea\u4f53\u5e72\u7ec6\u80de\u5728\u7597\u6548\u673a\u5236\u4e0a\u7684\u672c\u8d28\u533a\u522b\u3002<\/p>\n<p>\u7b2c\u4e8c\uff0c\u5e94\u601d\u8003\u5982\u4f55\u5b9e\u73b0\u5f02\u4f53\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e2a\u4f53\u5316\u4e0e\u7cbe\u51c6\u5316\u3002MSC\u7684\u7597\u6548\u5b58\u5728\u663e\u8457\u7684\u60a3\u8005\u5f02\u8d28\u6027\uff0c\u4e3b\u8981\u53d7\u7ec6\u80de\u672c\u8eab\u8d28\u91cf\uff08\u5982\u589e\u6b96\u6d3b\u6027\u3001\u514d\u75ab\u8c03\u8282\u80fd\u529b\uff09\u548c\u60a3\u8005\u4f53\u5185\u5fae\u73af\u5883\uff08\u5982\u5173\u952e\u7ec6\u80de\u56e0\u5b50\u6c34\u5e73\uff09\u7684\u53cc\u91cd\u5f71\u54cd\u3002<\/p>\n<p>\u56e0\u6b64\uff0c\u672a\u6765\u7684\u6838\u5fc3\u95ee\u9898\u5728\u4e8e\u5982\u4f55\u901a\u8fc7\u6cbb\u7597\u524d\u7684\u751f\u7269\u6807\u5fd7\u7269\uff08\u5982IFN-\u03b3\u3001IL-6\u6c34\u5e73\uff09\u68c0\u6d4b\u6765\u7b5b\u9009\u4f18\u52bf\u4eba\u7fa4\u6216\u4e3b\u52a8\u8c03\u8282\u60a3\u8005\u5fae\u73af\u5883\uff08\u4f8b\u5982\u4f7f\u7528IFN-\u03b3\u6216\u6258\u73e0\u5355\u6297\u8fdb\u884c\u9884\u5e72\u9884\uff09\uff0c\u4ece\u800c\u5236\u5b9a\u4e2a\u4f53\u5316\u7684\u6cbb\u7597\u7b56\u7565\uff0c\u4ee5\u63d0\u9ad8\u7597\u6548\u7684\u7a33\u5b9a\u6027\u548c\u53ef\u9884\u6d4b\u6027\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97AD%E7%9A%84%E5%8F%91%E5%B1%95%E8%B6%8B%E5%8A%BF\"><\/span><strong>\u5e72\u7ec6\u80de\u6cbb\u7597AD\u7684\u53d1\u5c55\u8d8b\u52bf<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5e72\u7ec6\u80de\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff08AD\uff09\u7684\u53d1\u5c55\u8d8b\u52bf\u9996\u5148\u4f53\u73b0\u5728\u6cbb\u7597\u7b56\u7565\u7684\u6839\u672c\u6027\u8f6c\u53d8\u3002\u672a\u6765\u7684\u91cd\u70b9\u662f\u4ece\u76ee\u524d\u4ec5\u9488\u5bf9\u96be\u6cbb\u6027\u60a3\u8005\u7684\u201c\u6700\u540e\u624b\u6bb5\u201d\uff0c\u8f6c\u5411\u5c06\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u7b49\u7597\u6cd5\u7528\u4e8e\u75be\u75c5\u7684\u65e9\u671f\u4e00\u7ebf\u6cbb\u7597\u3002<\/p>\n<p>\u8fd9\u79cd\u524d\u79fb\u65e8\u5728\u4ece\u6e90\u5934\u63a7\u5236\u75c5\u60c5\u8fdb\u5c55\uff0c\u4ece\u800c\u5927\u5e45\u51cf\u5c11\u5bf9\u6fc0\u7d20\u3001\u514d\u75ab\u6291\u5236\u5242\u7b49\u4f20\u7edf\u836f\u7269\u7684\u957f\u671f\u4f9d\u8d56\uff0c\u5728\u964d\u4f4e\u836f\u7269\u4e0d\u826f\u53cd\u5e94\u548c\u533b\u7597\u7ecf\u6d4e\u8d1f\u62c5\u7684\u540c\u65f6\uff0c\u6709\u671b\u5b9e\u73b0\u66f4\u6301\u4e45\u7684\u75c5\u60c5\u7f13\u89e3\uff0c\u6539\u5584\u60a3\u8005\u957f\u671f\u9884\u540e\u3002<\/p>\n<p>\u5176\u6b21\uff0c\u6cbb\u7597\u6a21\u5f0f\u5c06\u5411\u9ad8\u5ea6\u4e2a\u4f53\u5316\u4e0e\u7cbe\u51c6\u5316\u53d1\u5c55\u3002\u8fd9\u8981\u6c42\u5efa\u7acb\u57fa\u4e8e\u751f\u7269\u6807\u5fd7\u7269\uff08\u5982\u7279\u5b9a\u7ec6\u80de\u56e0\u5b50\u6c34\u5e73\uff09\u548c\u5206\u5b50\u5206\u578b\u7684\u8bca\u65ad\u4f53\u7cfb\uff0c\u4ee5\u9884\u6d4b\u7597\u6548\u548c\u6307\u5bfc\u6cbb\u7597\u3002\u5373\u4f7f\u5728MSC\u6cbb\u7597\u4e2d\uff0c\u7ef4\u6301\u671f\u7684\u91cd\u590d\u8f93\u6ce8\u7b56\u7565\u4e5f\u9700\u4f9d\u636e\u60a3\u8005\u7684\u5b9e\u65f6\u4e34\u5e8a\u6307\u6807\u8fdb\u884c\u52a8\u6001\u8c03\u6574\uff0c\u5b9e\u73b0\u201c\u91cf\u4f53\u88c1\u8863\u201d\u5f0f\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u4ee5\u5e94\u5bf9\u7597\u6548\u7684\u4e2a\u4f53\u5f02\u8d28\u6027\u548c\u63d0\u5347\u6cbb\u7597\u6548\u7387\u3002<\/p>\n<p>\u6700\u540e\uff0c\u6cbb\u7597\u65b9\u6848\u7684\u8303\u7574\u6b63\u4ece\u5355\u4e00\u7597\u6cd5\u5411\u534f\u540c\u4e0e\u8054\u5408\u6cbb\u7597\u62d3\u5c55\u3002MSC\u56e0\u5176\u591a\u9776\u70b9\u3001\u9ad8\u5b89\u5168\u6027\u7684\u72ec\u7279\u4f18\u52bf\uff0c\u4e0d\u4ec5\u53ef\u4f5c\u4e3a\u72ec\u7acb\u6709\u6548\u7684\u6cbb\u7597\u9009\u62e9\uff0c\u672a\u6765\u4e0e\u751f\u7269\u5236\u5242\u3001\u5c0f\u5206\u5b50\u836f\u7269\u4e43\u81f3\u5177\u6709\u514d\u75ab\u8c03\u8282\u4f5c\u7528\u7684\u4e2d\u836f\u6d3b\u6027\u6210\u5206\uff08\u5982\u6c34\u98de\u84df\u5bbe\u3001\u59dc\u9ec4\u7d20\uff09\u7684\u8054\u5408\u5e94\u7528\uff0c\u53ef\u80fd\u4ea7\u751f\u534f\u540c\u6548\u5e94\uff0c\u4e3a\u653b\u514b\u590d\u6742\u3001\u96be\u6cbb\u7684AD\u75c5\u4f8b\u5f00\u8f9f\u66f4\u5e7f\u9614\u7684\u524d\u666f\u3002<\/p>\n<section data-role=\"paragraph\">\n<h2><span class=\"ez-toc-section\" id=\"%E6%80%BB%E7%BB%93%E4%B8%8E%E5%B1%95%E6%9C%9B\"><\/span><strong>Summary and outlook<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<\/section>\n<p>\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u6b63\u6cbf\u7740\u4e09\u6761\u4e3b\u7ebf\u5411\u524d\u53d1\u5c55\uff1a<\/p>\n<p>\u9996\u5148\uff0c\u4ee5\u5f02\u4f53\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u4e3a\u4ee3\u8868\u7684\u7ec6\u80de\u7597\u6cd5\u6b63\u5c55\u73b0\u51fa\u6210\u4e3a\u65b0\u4e00\u4ee3\u4e3b\u6d41\u6cbb\u7597\u9009\u62e9\u7684\u5de8\u5927\u6f5c\u529b\u3002\u4e0d\u540c\u4e8e\u4f20\u7edf\u836f\u7269\u901a\u8fc7\u6291\u5236\u514d\u75ab\u6765\u53d1\u6325\u4f5c\u7528\uff0cMSC\u901a\u8fc7\u201c\u7ea0\u6b63\u514d\u75ab\u5931\u8861\u3001\u8bf1\u5bfc\u514d\u75ab\u8010\u53d7\u201d\u8fd9\u4e00\u6839\u672c\u6027\u673a\u5236\u5b9e\u73b0\u6cbb\u7597\uff0c\u5177\u6709\u5b89\u5168\u6027\u9ad8\u3001\u7597\u6548\u6301\u4e45\u7684\u7279\u70b9\u3002<\/p>\n<p>\u5176\u6210\u836f\u6027\u4f18\u52bf\u660e\u663e\uff0c\u80fd\u591f\u5b9e\u73b0\u5927\u89c4\u6a21\u6269\u589e\u548c\u81ea\u52a8\u5316\u751f\u4ea7\uff0c\u9884\u793a\u7740\u672a\u6765\u201c\u4ef7\u5ec9\u7269\u7f8e\u201d\u7684MSC\u65b0\u836f\u6709\u671b\u5e7f\u6cdb\u8fdb\u5165\u4e34\u5e8a\uff0c\u4e3a\u533b\u751f\u548c\u60a3\u8005\u63d0\u4f9b\u5168\u65b0\u7684\u6cbb\u7597\u6b66\u5668\u3002<\/p>\n<p>\u5176\u6b21\uff0c\u672a\u6765\u7684\u7814\u7a76\u5c06\u5411\u66f4\u6df1\u5c42\u7684\u673a\u5236\u63a2\u7d22\u548c\u66f4\u5e7f\u6cdb\u7684\u8054\u5408\u6cbb\u7597\u7b56\u7565\u62d3\u5c55\u3002\u57fa\u7840\u7814\u7a76\u5c06\u7ee7\u7eed\u9610\u660e\u9020\u8840\u5e72\u7ec6\u80de\uff08HSC\uff09\u4e0eMSC\u5728AD\u53d1\u75c5\u4e2d\u7684\u5177\u4f53\u4f5c\u7528\u548c\u8c03\u63a7\u7f51\u7edc\uff0c\u5e76\u901a\u8fc7\u5bf9\u6bd4\u4e0d\u540c\u7597\u6cd5\uff08\u5982\u5f02\u4f53\/\u81ea\u4f53\u79fb\u690d\u3001MSC\u4e0eCAR-T\u3001MSC\u4e0e\u751f\u7269\u5236\u5242\uff09\u7684\u7597\u6548\u4e0e\u673a\u5236\u5dee\u5f02\uff0c\u4e3a\u7cbe\u51c6\u9009\u62e9\u6cbb\u7597\u65b9\u6848\u63d0\u4f9b\u4f9d\u636e\u3002<\/p>\n<p>\u540c\u65f6\uff0c\u5c06\u91cd\u70b9\u63a2\u7d22MSC\u4e0e\u73b0\u6709\u7597\u6cd5\uff08\u5982CAR-T\u3001\u751f\u7269\u5236\u5242\u3001\u4f20\u7edf\u836f\u7269\u4e43\u81f3\u4e2d\u836f\u6709\u6548\u6210\u5206\uff09\u7684\u8054\u5408\u5e94\u7528\uff0c\u65e8\u5728\u5f00\u53d1\u51fa\u7597\u6548\u53e0\u52a0\u6216\u4e92\u8865\u7684\u534f\u540c\u6cbb\u7597\u65b9\u6848\uff0c\u653b\u514b\u590d\u6742\u96be\u6cbb\u7684\u75c5\u4f8b\u3002<\/p>\n<p>\u6700\u7ec8\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u672a\u6765\u53d1\u5c55\u8def\u5f84\u662f\u660e\u786e\u7684\uff0c\u5373\u63a8\u52a8\u6cbb\u7597\u5173\u53e3\u524d\u79fb\u5e76\u5b9e\u73b0\u9ad8\u5ea6\u4e2a\u4f53\u5316\u3002\u5176\u76ee\u6807\u662f\u4ece\u5f53\u524d\u4f5c\u4e3a\u96be\u6cbb\u6027\u60a3\u8005\u7684\u201c\u6700\u540e\u9009\u62e9\u201d\uff0c\u8f6c\u53d8\u4e3a\u5728\u75be\u75c5\u65e9\u671f\u8fdb\u884c\u5e72\u9884\u7684\u4e00\u7ebf\u7597\u6cd5\uff0c\u4ece\u800c\u6709\u671b\u5b9e\u73b0\u957f\u671f\u7f13\u89e3\u751a\u81f3\u529f\u80fd\u6027\u6cbb\u6108\uff0c\u51cf\u5c11\u5bf9\u4f20\u7edf\u836f\u7269\u7684\u7ec8\u8eab\u4f9d\u8d56\u3002<\/p>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c\u6709\u7406\u7531\u76f8\u4fe1\u5e72\u7ec6\u80de\u6cbb\u7597AD\u5c06\u53d6\u5f97\u65b0\u7684\u7a81\u7834\u3002\u7ec6\u80de\u6cbb\u7597\u662fAD\u6cbb\u7597\u7684\u53d1\u5c55\u65b9\u5411\u548c\u5fc5\u7ecf\u4e4b\u8def\uff0c\u5176\u5728AD\u6cbb\u7597\u4e2d\u7684\u751f\u547d\u529b\u548c\u201c\u529f\u8fc7\u662f\u975e\u201d\u5c06\u7531\u4e34\u5e8a\u5b9e\u8df5\u53ca\u65f6\u95f4\u6765\u56de\u7b54\u3002<\/p>\n<\/section>\n<blockquote>\n<p data-pm-slice=\"0 0 []\">References:<\/p>\n<p data-pm-slice=\"0 0 []\">[1]:<span data-pm-slice=\"0 0 []\">\u5b59\u51cc\u4e91. \u5e72\u7ec6\u80de\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u75c5\u7684\u6f14\u53d8\u548c\u5c55\u671b. \u4e2d\u534e\u98ce\u6e7f\u75c5\u5b66\u6742\u5fd7\uff0c2025\uff0c29(02):89-92. DOI:10.3760\/cma.j.cn141217-20250204-00032<\/span><\/p>\n<p data-pm-slice=\"0 0 []\"><span data-pm-slice=\"0 0 []\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[2] <\/span><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Jasim, SA, Yumashev, AV, Abdelbasset, WK\u00a0<\/span><\/span><i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7b49\u3002<\/span><\/span><\/i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u00a0\u63ed\u793a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u5728\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u4e2d\u7684\u4e34\u5e8a\u5e94\u7528\u3002\u00a0<\/span><\/span><i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597<\/span><\/span><\/i>\u00a0<b><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">13<\/span><\/span><\/b><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> , 101 (2022)\u3002https:\/\/doi.org\/10.1186\/s13287-022-02782-7<\/span><\/span><\/span><\/p>\n<p data-pm-slice=\"0 0 []\"><span data-pm-slice=\"0 0 []\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[3] <\/span><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Hen B, Chen Z, He M, Zhang L, Yang L, Wei L (2024) \u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u4f5c\u4e3a\u81ea\u8eab\u708e\u75c7\u6027\u75be\u75c5\u8c03\u8282\u56e0\u5b50\u7684\u6700\u65b0\u8fdb\u5c55\u3002Front\u00a0 <\/span><\/span><i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">. Immunol.<\/span><\/span><\/i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a015:1525380\u3002doi: 10.3389\/fimmu.2024.1525380<\/span><\/span><\/span><\/p>\n<p data-pm-slice=\"0 0 []\"><span data-pm-slice=\"0 0 []\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[4] <\/span><\/span><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Chen Y, Li X, Zhang J, Peng J, Huang F, Bao J, Fan Y, Huang S (2025) \u5168\u7403\u5e72\u7ec6\u80de\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff1a\u8d8b\u52bf\u4e0e\u672a\u6765\u65b9\u5411\u3002Front\u00a0 <\/span><\/span><i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">. Immunol.<\/span><\/span><\/i><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a016:1616231\u3002doi: 10.3389\/fimmu.2025.1616231<\/span><\/span><\/span><\/p>\n<p data-pm-slice=\"0 0 []\"><span data-pm-slice=\"0 0 []\">Disclaimer: This article is intended only to disseminate scientific knowledge and share industry perspectives, and does not constitute any clinical diagnostic advice! The information published by Hangi Stem Cells is not a substitute for the professional advice of a physician or pharmacist. If you have any questions about copyright or other issues, please feel free to contact me.<\/span><\/p>\n<\/blockquote>","protected":false},"excerpt":{"rendered":"<p>\u81ea\u8eab\u514d\u75ab\u75c5\uff08AD\uff09\u662f\u4e00\u7c7b\u4ee5\u514d\u75ab\u7cfb\u7edf\u5f02\u5e38\u653b\u51fb\u81ea\u8eab\u7ec4\u7ec7\u4e3a\u7279\u5f81\u7684\u590d\u6742\u75be\u75c5\uff0c\u5168\u7403\u60a3\u8005\u6570\u91cf\u5e9e\u5927\u4e14\u6cbb\u7597\u9700\u6c42\u8feb\u5207\u3002\u4f20\u7edf\u7597\u6cd5\u5982 [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[76],"tags":[150,256,191,178],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20946"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/comments?post=20946"}],"version-history":[{"count":2,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20946\/revisions"}],"predecessor-version":[{"id":20952,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/20946\/revisions\/20952"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media?parent=20946"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/categories?post=20946"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/tags?post=20946"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}