{"id":21016,"date":"2025-12-19T15:51:19","date_gmt":"2025-12-19T07:51:19","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=21016"},"modified":"2025-12-19T15:51:40","modified_gmt":"2025-12-19T07:51:40","slug":"https-www-hjtdsm-cn-stem-cells-mscs-21016-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/21016.html","title":{"rendered":"\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u7684\u4e34\u5e8a\u5e94\u7528\u524d\u666f\uff1a\u957f\u671f\u7597\u6548\u3001\u5b89\u5168\u6027\u600e\u4e48\u6837\uff1f"},"content":{"rendered":"<section data-role=\"outer\" data-pm-slice=\"0 0 []\">\n<section data-role=\"paragraph\"><a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20541.html\/\" target=\"_blank\" rel=\"noopener\">\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\uff08RA\uff09<\/a>\u662f\u4e00\u79cd\u591a\u56e0\u7d20\u5171\u540c\u4f5c\u7528\u7684<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/20946.html\/\" target=\"_blank\" rel=\"noopener\">autoimmune disease<\/a>\uff0c\u4ee5\u4fb5\u8680\u6027\u5173\u8282\u708e\u4e3a\u4e3b\u8981\u7279\u5f81\u3002\u8be5\u75be\u75c5\u53ef\u5bfc\u81f4\u5173\u8282\u75bc\u75db\u3001\u80bf\u80c0\u53ca\u7578\u5f62\uff0c\u4e25\u91cd\u5f71\u54cd\u60a3\u8005\u7684\u751f\u6d3b\u8d28\u91cf\u3002\u5176\u53d1\u75c5\u6d89\u53ca\u9057\u4f20\u3001\u73af\u5883\u53ca\u514d\u75ab\u7b49\u591a\u79cd\u56e0\u7d20\u7684\u590d\u6742\u4ea4\u4e92\uff0c\u5177\u4f53\u673a\u5236\u81f3\u4eca\u5c1a\u672a\u5b8c\u5168\u9610\u660e\uff08\u56fe1\uff09\u3002<\/p>\n<section>\n<div id=\"attachment_21023\" style=\"width: 1825px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-21023\" class=\"wp-image-21023 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0001-m.jpg\" alt=\"\" width=\"1815\" height=\"1704\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0001-m.jpg 1815w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0001-m-300x282.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0001-m-1024x961.jpg 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0001-m-768x721.jpg 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0001-m-1536x1442.jpg 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0001-m-13x12.jpg 13w\" sizes=\"(max-width: 1815px) 100vw, 1815px\" \/><p id=\"caption-attachment-21023\" class=\"wp-caption-text\">\u56fe1\uff1a\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u4e2d\u4e0d\u540c\u56e0\u7d20\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528<\/p><\/div>\n<\/section>\n<p>\u76ee\u524d\uff0cRA\u7684\u5e38\u89c4\u6cbb\u7597\u65b9\u6848\u4ecd\u5b58\u5728\u8bf8\u591a\u5c40\u9650\u3002\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u7597\u6cd5\u51ed\u501f\u5176\u72ec\u7279\u7684\u751f\u7269\u5b66\u7279\u6027\u2014\u2014\u5305\u62ec\u591a\u7cfb\u5206\u5316\u6f5c\u80fd\u3001\u514d\u75ab\u8c03\u8282\u529f\u80fd\u3001\u4f4e\u514d\u75ab\u539f\u6027\u4ee5\u53ca\u5f3a\u5927\u7684\u7ec4\u7ec7\u4fee\u590d\u80fd\u529b\u2014\u2014\u5728\u4e34\u5e8a\u524d\u4e0e\u4e34\u5e8a\u7814\u7a76\u4e2d\u5747\u663e\u793a\u51fa\u826f\u597d\u7684\u6cbb\u7597\u524d\u666f\u3002<\/p>\n<p>\u5728\u6b64\u80cc\u666f\u4e0b\uff0c\u7cfb\u7edf\u8bc4\u4f30\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u7684\u957f\u671f\u7597\u6548\u4e0e\u5b89\u5168\u6027\u663e\u5f97\u5c24\u4e3a\u8feb\u5207\u3002\u4e3a\u6b64\uff0c\u5357\u4eac\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u9f13\u697c\u533b\u9662\u98ce\u6e7f\u514d\u75ab\u79d1\u8054\u5408\u6e05\u534e\u5927\u5b66\u751f\u547d\u79d1\u5b66\u4e2d\u5fc3\u3001\u6e05\u534e\u5927\u5b66\u514d\u75ab\u5b66\u7814\u7a76\u6240\u7b49\u673a\u6784\uff0c\u8fd1\u65e5\u5728\u671f\u520a\u300a\u98ce\u6e7f\u75c5\u4e0e\u81ea\u8eab\u514d\u75ab\u5b66\u4e3b\u9875\u300b\u4e0a\u53d1\u8868\u9898\u4e3a<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rai2.70032\" target=\"_blank\" rel=\"noopener nofollow\">\u201c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u6cbb\u7597\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\uff1a\u957f\u671f\u7597\u6548\u3001\u5b89\u5168\u6027\u53ca\u673a\u5236\u7814\u7a76\u201d<\/a>\u7684\u7efc\u8ff0\u6587\u7ae0\u3002<\/p>\n<section><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-21024 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-19_120001_561.png\" alt=\"\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u7684\u4e34\u5e8a\u5e94\u7528\u524d\u666f\uff1a\u957f\u671f\u7597\u6548\u3001\u5b89\u5168\u6027\u600e\u4e48\u6837\uff1f\" width=\"710\" height=\"292\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/ScreenShot_2025-12-19_120001_561.png 710w, 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href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/21016.html\/#%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97RA%E7%9A%84%E5%BD%B1%E5%93%8D%E5%9B%A0%E7%B4%A0\" >\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597RA\u7684\u5f71\u54cd\u56e0\u7d20<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/21016.html\/#%E8%AE%A8%E8%AE%BA%E4%B8%8E%E7%BB%93%E6%9E%9C\" >\u8ba8\u8bba\u4e0e\u7ed3\u679c<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/21016.html\/#%E4%B8%80%E3%80%81%E6%98%BE%E8%91%97%E7%9A%84%E4%B8%B4%E5%BA%8A%E7%96%97%E6%95%88%E4%B8%8E%E6%B2%BB%E7%96%97%E6%BD%9C%E5%8A%9B\" >\u4e00\u3001\u663e\u8457\u7684\u4e34\u5e8a\u7597\u6548\u4e0e\u6cbb\u7597\u6f5c\u529b<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/21016.html\/#%E4%BA%8C%E3%80%81%E8%89%AF%E5%A5%BD%E7%9A%84%E5%AE%89%E5%85%A8%E6%80%A7%E4%B8%8E%E4%B8%A5%E6%A0%BC%E7%9A%84%E8%B4%A8%E9%87%8F%E6%8E%A7%E5%88%B6\" >\u4e8c\u3001\u826f\u597d\u7684\u5b89\u5168\u6027\u4e0e\u4e25\u683c\u7684\u8d28\u91cf\u63a7\u5236<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/21016.html\/#%E4%B8%89%E3%80%81%E6%8A%80%E6%9C%AF%E4%BC%98%E5%8C%96%E4%B8%8E%E7%96%97%E6%95%88%E5%A2%9E%E5%BC%BA%E7%AD%96%E7%95%A5\" >\u4e09\u3001\u6280\u672f\u4f18\u5316\u4e0e\u7597\u6548\u589e\u5f3a\u7b56\u7565<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/21016.html\/#%E5%9B%9B%E3%80%81%E5%BD%93%E5%89%8D%E5%B1%80%E9%99%90%E4%B8%8E%E6%9C%AA%E6%9D%A5%E5%8F%91%E5%B1%95%E6%96%B9%E5%90%91\" 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height=\"1661\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0002-m.jpg 1821w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0002-m-300x274.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0002-m-1024x934.jpg 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0002-m-768x701.jpg 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0002-m-1536x1401.jpg 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0002-m-13x12.jpg 13w\" sizes=\"(max-width: 1821px) 100vw, 1821px\" \/><p id=\"caption-attachment-21022\" class=\"wp-caption-text\">\u56fe2\uff1a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7684\u7279\u6027\u53ca\u5176\u5728\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u4e2d\u7684\u6cbb\u7597\u673a\u5236\u3002<\/p><\/div>\n<\/section>\n<\/section>\n<p>MSCs\u7684\u6838\u5fc3\u5b9a\u4e49\u662f\u4e00\u79cd\u5177\u6709\u81ea\u6211\u66f4\u65b0\u80fd\u529b\u7684\u6210\u4f53\u57fa\u8d28\u7ec6\u80de\uff0c\u5e7f\u6cdb\u5206\u5e03\u4e8e\u9aa8\u9ad3\u3001\u8102\u80aa\u3001\u8110\u5e26\u7b49\u591a\u79cd\u7ec4\u7ec7\u4e2d\u3002\u6839\u636e\u56fd\u9645\u7ec6\u80de\u6cbb\u7597\u5b66\u4f1a\uff08ISCT\uff09\u66f4\u65b0\u540e\u7684\u6807\u51c6\uff0c\u5176\u9274\u5b9a\u91cd\u70b9\u5df2\u4ece\u4f20\u7edf\u7684\u201c\u4e09\u7cfb\u5206\u5316\u201d\u6f5c\u80fd\u8f6c\u5411\u7279\u5b9a\u7684\u8868\u9762\u6807\u5fd7\u7269\uff08\u5982\u8868\u8fbeCD73\u3001CD90\u3001CD105\uff0c\u800c\u4e0d\u8868\u8fbeCD34\u3001CD45\u7b49\u9020\u8840\u6807\u5fd7\u7269\uff09\u4ee5\u53ca\u660e\u786e\u7684\u7ec4\u7ec7\u6765\u6e90\u3002\u5728\u7279\u5b9a\u8bf1\u5bfc\u6761\u4ef6\u4e0b\uff0cMSCs\u4ecd\u80fd\u5206\u5316\u4e3a\u6210\u9aa8\u7ec6\u80de\u3001\u8102\u80aa\u7ec6\u80de\u548c\u8f6f\u9aa8\u7ec6\u80de\uff0c\u8fd9\u6784\u6210\u4e86\u5176\u53c2\u4e0e\u7ec4\u7ec7\u4fee\u590d\u7684\u57fa\u7840\u80fd\u529b\u3002<\/p>\n<p>MSCs\u6700\u7a81\u51fa\u7684\u7279\u6027\u5728\u4e8e\u5176\u5f3a\u5927\u7684\u514d\u75ab\u8c03\u8282\u529f\u80fd\u4e0e\u65c1\u5206\u6ccc\u6548\u5e94\u3002\u5b83\u4eec\u53ef\u901a\u8fc7\u7ec6\u80de\u76f4\u63a5\u63a5\u89e6\u6216\u5206\u6ccc\u8f6c\u5316\u751f\u957f\u56e0\u5b50-\u03b2\uff08TGF-\u03b2\uff09\u3001\u5432\u54da\u80fa2,3-\u53cc\u52a0\u6c27\u9176\uff08IDO\uff09\u7b49\u56e0\u5b50\uff0c\u6291\u5236T\u7ec6\u80de\u3001B\u7ec6\u80de\u7684\u5f02\u5e38\u589e\u6b96\uff0c\u963b\u788d\u6811\u7a81\u72b6\u7ec6\u80de\u6210\u719f\uff0c\u5e76\u8c03\u8282\u81ea\u7136\u6740\u4f24\u7ec6\u80de\u7684\u529f\u80fd\uff08\u56fe3\uff09\u3002\u8fd9\u4e00\u7279\u6027\u4f7f\u5176\u5728\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff08\u5982RA\uff09\u53ca\u51cf\u8f7b\u79fb\u690d\u6392\u65a5\u53cd\u5e94\u4e2d\u5177\u6709\u91cd\u8981\u4ef7\u503c\u3002\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u7814\u7a76\u5747\u8bc1\u5b9e\uff0cMSCs\u80fd\u591f\u6709\u6548\u51cf\u8f7b\u708e\u75c7\u3001\u4fc3\u8fdb\u7ec4\u7ec7\u4fee\u590d\u5e76\u6539\u5584\u5173\u8282\u529f\u80fd\u3002<\/p>\n<section>\n<div id=\"attachment_21021\" style=\"width: 1827px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-21021\" class=\"wp-image-21021 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0003-m.jpg\" alt=\"\" width=\"1817\" height=\"1003\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0003-m.jpg 1817w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0003-m-300x166.jpg 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0003-m-1024x565.jpg 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0003-m-768x424.jpg 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0003-m-1536x848.jpg 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/rai270032-fig-0003-m-18x10.jpg 18w\" sizes=\"(max-width: 1817px) 100vw, 1817px\" \/><p id=\"caption-attachment-21021\" class=\"wp-caption-text\">\u56fe3\uff1a\u95f4\u5145\u8d28\u57fa\u8d28\u7ec6\u80de\uff1a\u8d77\u6e90\u3001\u8868\u578b\u548c\u529f\u80fd\u7279\u5f81\u3002<\/p><\/div>\n<\/section>\n<p>\u6b64\u5916\uff0cMSCs\u5177\u6709\u4f4e\u514d\u75ab\u539f\u6027\u548c\u826f\u597d\u7684\u4f53\u5916\u6269\u589e\u80fd\u529b\uff0c\u4e3a\u5176\u4e34\u5e8a\u5e94\u7528\u63d0\u4f9b\u4e86\u53ef\u884c\u6027\u3002\u7531\u4e8e\u8868\u9762\u4e3b\u8981\u7ec4\u7ec7\u76f8\u5bb9\u6027\u590d\u5408\u4f53II\u7c7b\u5206\u5b50\u53ca\u5171\u523a\u6fc0\u5206\u5b50\u8868\u8fbe\u7f3a\u5931\uff0cMSCs\u4e0d\u6613\u88ab\u5bbf\u4e3b\u514d\u75ab\u7cfb\u7edf\u8bc6\u522b\u548c\u6392\u65a5\u3002\u901a\u8fc7\u4f7f\u7528\u5316\u5b66\u6210\u5206\u660e\u786e\u7684\u65e0\u8840\u6e05\u57f9\u517b\u57fa\u6216\u8840\u5c0f\u677f\u88c2\u89e3\u7269\uff0c\u53ef\u5b9e\u73b0MSCs\u7684\u5927\u89c4\u6a21\u3001\u6807\u51c6\u5316\u6269\u589e\u3002<\/p>\n<p>\u7814\u7a76\u8fd8\u8868\u660e\uff0c\u5229\u7528\u5e72\u6270\u7d20-\u03b3\u7b49\u7ec6\u80de\u56e0\u5b50\u8fdb\u884c\u9884\u5904\u7406\u6216\u8fdb\u884c\u7279\u5b9a\u57fa\u56e0\u4fee\u9970\uff0c\u53ef\u8fdb\u4e00\u6b65\u8c03\u63a7\u548c\u589e\u5f3aMSCs\u7684\u514d\u75ab\u8c03\u8282\u529f\u80fd\u4e0e\u6cbb\u7597\u6548\u679c\uff0c\u4f46\u5176\u6700\u7ec8\u7597\u6548\u4ecd\u9ad8\u5ea6\u4f9d\u8d56\u4e8e\u6240\u5904\u5fae\u73af\u5883\u3002<\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%88MSCs%EF%BC%89%E6%B2%BB%E7%96%97%E7%B1%BB%E9%A3%8E%E6%B9%BF%E5%85%B3%E8%8A%82%E7%82%8E%EF%BC%88RA%EF%BC%89%E7%9A%84%E4%BD%9C%E7%94%A8%E6%9C%BA%E5%88%B6\"><\/span><strong>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u6cbb\u7597\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\uff08RA\uff09\u7684\u4f5c\u7528\u673a\u5236<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>MSCs\u6cbb\u7597RA\u7684\u4f5c\u7528\u673a\u5236\u6d89\u53ca\u591a\u4e2a\u65b9\u9762\uff0c\u4e3b\u8981\u5305\u62ec\u514d\u75ab\u8c03\u8282\u3001\u6297\u708e\u4f5c\u7528\u3001\u4fc3\u8fdb\u7ec4\u7ec7\u4fee\u590d\u4ee5\u53ca\u6291\u5236\u7834\u9aa8\u7ec6\u80de\u751f\u6210\u3002\u8fd9\u4e9b\u673a\u5236\u76f8\u4e92\u534f\u540c\uff0c\u5171\u540c\u53d1\u6325\u6cbb\u7597\u6548\u5e94\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E9%A6%96%E5%85%88%EF%BC%8C%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%B1%BB%E9%A3%8E%E6%B9%BF%E5%85%B3%E8%8A%82%E7%82%8E%E7%9A%84%E6%A0%B8%E5%BF%83%E6%9C%BA%E5%88%B6%E5%9C%A8%E4%BA%8E%E5%85%B6%E5%BC%BA%E5%A4%A7%E7%9A%84%E5%85%8D%E7%96%AB%E8%B0%83%E8%8A%82%E8%83%BD%E5%8A%9B%E3%80%82\"><\/span>\u9996\u5148\uff0c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u7684\u6838\u5fc3\u673a\u5236\u5728\u4e8e\u5176\u5f3a\u5927\u7684\u514d\u75ab\u8c03\u8282\u80fd\u529b\u3002<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>MSCs\u80fd\u591f\u76f4\u63a5\u5e72\u9884RA\u53d1\u75c5\u4e2d\u7684\u5173\u952e\u514d\u75ab\u7ec6\u80de\uff0c\u6062\u590d\u514d\u75ab\u7a33\u6001\u3002\u5b83\u4eec\u901a\u8fc7\u6291\u5236T\u7ec6\u80de\u7684\u5f02\u5e38\u6d3b\u5316\u548c\u589e\u6b96\uff0c\u5e76\u5206\u6cccIL-10\u3001TGF-\u03b2\u7b49\u56e0\u5b50\uff0c\u4fc3\u8fdb\u5177\u6709\u514d\u75ab\u6291\u5236\u529f\u80fd\u7684\u8c03\u8282\u6027T\u7ec6\u80de\u751f\u6210\u3002\u540c\u65f6\uff0cMSCs\u8fd8\u80fd\u6291\u5236B\u7ec6\u80de\u4ea7\u751f\u81ea\u8eab\u6297\u4f53\uff0c\u5e76\u963b\u788d\u6811\u7a81\u72b6\u7ec6\u80de\u7684\u6210\u719f\uff0c\u4ece\u591a\u4e2a\u73af\u8282\u51cf\u8f7b\u81ea\u8eab\u514d\u75ab\u653b\u51fb\u3002<\/p>\n<h3><span class=\"ez-toc-section\" 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id=\"attachment_21028\" style=\"width: 2384px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-21028\" class=\"wp-image-21028 size-full\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f3_Sheet13-1.png\" alt=\"\" width=\"2374\" height=\"898\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f3_Sheet13-1.png 2374w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f3_Sheet13-1-300x113.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f3_Sheet13-1-1024x387.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f3_Sheet13-1-768x291.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f3_Sheet13-1-1536x581.png 1536w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f3_Sheet13-1-2048x775.png 2048w, 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src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f2_Sheet13.png\" alt=\"\" width=\"1398\" height=\"456\" title=\"\" srcset=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f2_Sheet13.png 1398w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f2_Sheet13-300x98.png 300w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f2_Sheet13-1024x334.png 1024w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f2_Sheet13-768x251.png 768w, https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2025\/12\/\u5de5\u4f5c\u7c3f2_Sheet13-18x6.png 18w\" sizes=\"(max-width: 1398px) 100vw, 1398px\" \/><p id=\"caption-attachment-21029\" class=\"wp-caption-text\">\u88681\uff1a\u4e0d\u540c\u6765\u6e90MSC\u7684\u7279\u6027\u6bd4\u8f83\u3002<\/p><\/div>\n<\/section>\n<p>\u9996\u5148\uff0c\u7ec6\u80de\u6765\u6e90\u4e0e\u81ea\u8eab\u7279\u6027\u663e\u8457\u5f71\u54cd\u7597\u6548\u3002\u4e0d\u540c\u7ec4\u7ec7\u6765\u6e90\u7684MSCs\u5728\u5206\u5316\u6f5c\u80fd\u3001\u514d\u75ab\u8c03\u8282\u80fd\u529b\u548c\u589e\u6b96\u6d3b\u529b\u4e0a\u5b58\u5728\u5dee\u5f02\u3002\u4f8b\u5982\uff0c\u4e34\u5e8a\u524d\u7814\u7a76\u8868\u660e\uff0c\u5728RA\u52a8\u7269\u6a21\u578b\u4e2d\uff0c\u9aa8\u9ad3\u6765\u6e90\u7684MSCs\u53ef\u80fd\u6bd4\u8102\u80aa\u6765\u6e90\u7684MSCs\u5c55\u73b0\u51fa\u66f4\u5f3a\u7684\u514d\u75ab\u8c03\u8282\u7279\u6027\uff1b\u800c\u8110\u5e26\u6765\u6e90\u7684MSCs\u5219\u56e0\u5176\u91c7\u96c6\u4fbf\u5229\u3001\u4f4e\u514d\u75ab\u539f\u6027\u548c\u5f3a\u589e\u6b96\u80fd\u529b\uff0c\u5728\u4e34\u5e8a\u7814\u7a76\u4e2d\u663e\u793a\u51fa\u826f\u597d\u7684\u5e94\u7528\u524d\u666f\u3002<\/p>\n<p>\u5176\u6b21\uff0c\u6cbb\u7597\u65b9\u6848\u7684\u5177\u4f53\u53c2\u6570\u662f\u51b3\u5b9a\u7597\u6548\u7684\u6838\u5fc3\u53ef\u63a7\u56e0\u7d20\u3002\u8fd9\u5305\u62ec\u7ed9\u836f\u7684\u5242\u91cf\u3001\u9014\u5f84\u3001\u9891\u7387\u4ee5\u53ca\u7ec6\u80de\u7684\u9884\u5904\u7406\u65b9\u6cd5\u3002\u5242\u91cf\u9700\u5728\u5b89\u5168\u6709\u6548\u7684\u7a97\u53e3\u5185\u4f18\u5316\uff0c\u8fc7\u4f4e\u53ef\u80fd\u65e0\u6548\uff0c\u8fc7\u9ad8\u5219\u53ef\u80fd\u589e\u52a0\u98ce\u9669\u3002\u7ed9\u836f\u9014\u5f84\u76f4\u63a5\u5f71\u54cd\u7ec6\u80de\u5206\u5e03\u548c\u4f5c\u7528\u65b9\u5f0f\uff1a\u9759\u8109\u6ce8\u5c04\u5229\u4e8e\u5168\u8eab\u6027\u514d\u75ab\u8c03\u8282\uff0c\u5173\u8282\u5185\u6ce8\u5c04\u53ef\u5b9e\u73b0\u75c5\u7076\u5c40\u90e8\u9ad8\u6d53\u5ea6\u805a\u96c6\u3002\u6b64\u5916\uff0c\u8f93\u6ce8\u524d\u4f7f\u7528\u7ec6\u80de\u56e0\u5b50\u7b49\u5bf9MSCs\u8fdb\u884c\u9884\u5904\u7406\uff0c\u53ef\u6709\u6548\u589e\u5f3a\u5176\u514d\u75ab\u8c03\u8282\u548c\u6297\u708e\u529f\u80fd\u3002<\/p>\n<p>\u6700\u540e\uff0c\u60a3\u8005\u4e2a\u4f53\u72b6\u51b5\u4e0e\u4f53\u5185\u5fae\u73af\u5883\u662f\u5f71\u54cd\u6cbb\u7597\u53cd\u5e94\u7684\u5173\u952e\u53d8\u91cf\u3002\u60a3\u8005\u7684\u5e74\u9f84\u3001\u75be\u75c5\u6d3b\u52a8\u5ea6\u3001\u5408\u5e76\u75c7\u4ee5\u53ca\u65e2\u5f80\u6cbb\u7597\u60c5\u51b5\u7b49\u4e2a\u4f53\u5dee\u5f02\uff0c\u4f1a\u5bfc\u81f4\u5bf9MSCs\u7597\u6cd5\u7684\u53cd\u5e94\u4e0d\u540c\u3002\u66f4\u91cd\u8981\u7684\u662f\uff0c\u60a3\u8005\u708e\u75c7\u5173\u8282\u5c40\u90e8\u7684\u5fae\u73af\u5883\uff08\u5982\u7279\u5b9a\u7ec6\u80de\u56e0\u5b50\u548c\u8d8b\u5316\u56e0\u5b50\u7684\u6c34\u5e73\uff09\u4f1a\u76f4\u63a5\u5f71\u54cd\u8f93\u6ce8\u540eMSCs\u7684\u5b58\u6d3b\u3001\u5f52\u5de2\u53ca\u5176\u529f\u80fd\u53d1\u6325\uff0c\u4ece\u800c\u6700\u7ec8\u51b3\u5b9a\u6cbb\u7597\u7684\u6210\u8d25\u3002<\/p>\n<h2><span 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data-pm-slice=\"0 0 []\">\u4e3b\u8981\u53c2\u8003\u8d44\u6599\uff1a[1]:<span data-pm-slice=\"0 0 []\">Chen\u00a0Y<\/span>,\u00a0Gao\u00a0R,\u00a0Guo\u00a0X, et al.\u00a0Mesenchymal stromal cell therapy for rheumatoid arthritis: long-term efficacy, safety, and mechanistic insights.\u00a0<i>Rheumatol Autoimmun<\/i>.\u00a02025;\u00a01-13.\u00a0doi:10.1002\/rai2.70032<\/p>\n<p data-pm-slice=\"0 0 []\">Disclaimer: This article is intended only to disseminate scientific knowledge and share industry perspectives, and does not constitute any clinical diagnostic advice! The information published by Hangi Stem Cells is not a substitute for the professional advice of a physician or pharmacist. If you have any questions about copyright or other issues, please feel free to contact me.<\/p>\n<\/blockquote>","protected":false},"excerpt":{"rendered":"<p>\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\uff08RA\uff09\u662f\u4e00\u79cd\u591a\u56e0\u7d20\u5171\u540c\u4f5c\u7528\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u4ee5\u4fb5\u8680\u6027\u5173\u8282\u708e\u4e3a\u4e3b\u8981\u7279\u5f81\u3002\u8be5\u75be\u75c5\u53ef\u5bfc\u81f4\u5173\u8282\u75bc\u75db\u3001\u80bf [&hellip;]<\/p>","protected":false},"author":1,"featured_media":21030,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[61],"tags":[230,260,178],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21016"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/comments?post=21016"}],"version-history":[{"count":2,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21016\/revisions"}],"predecessor-version":[{"id":21032,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21016\/revisions\/21032"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media\/21030"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media?parent=21016"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/categories?post=21016"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/tags?post=21016"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}