{"id":21364,"date":"2026-01-27T01:12:25","date_gmt":"2026-01-26T09:12:25","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/stem-cells\/stem-cell-therapy\/21364.html"},"modified":"2026-01-27T01:12:25","modified_gmt":"2026-01-26T09:12:25","slug":"2025%e5%b9%b41-12%e6%9c%88%ef%bc%9a%e5%b9%b2%e7%bb%86%e8%83%9e%e6%b2%bb%e7%96%97%e7%8b%bc%e7%96%ae%e6%80%a7%e8%82%be%e7%82%8e%e6%9c%80%e6%96%b0%e4%b8%b4%e5%ba%8a%e8%bf%9b%e5%b1%95%e6%b1%87%e6%80%bb","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html","title":{"rendered":"2025\u5e741-12\u6708\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55\u6c47\u603b"},"content":{"rendered":"<p>\u72fc\u75ae\u6027\u80be\u708e\uff08Lupus Nephritis\uff0cLN\uff09\u662f\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u6700\u5e38\u89c1\u4e14\u6700\u4e25\u91cd\u7684\u5e76\u53d1\u75c7\u4e4b\u4e00\uff0c\u7531\u514d\u75ab\u7d0a\u4e71\u5f15\u53d1\u7684\u6301\u7eed\u708e\u75c7\u53ef\u635f\u5bb3\u80be\u810f\u7ed3\u6784\uff0c\u5bfc\u81f4\u86cb\u767d\u5c3f\u3001\u80be\u529f\u80fd\u4e0b\u964d\uff0c\u4e25\u91cd\u65f6\u53ef\u53d1\u5c55\u4e3a\u80be\u8870\u7aed\uff0c\u7ed9\u60a3\u8005\u751f\u6d3b\u548c\u9884\u540e\u5e26\u6765\u6c89\u91cd\u8d1f\u62c5\u3002<\/p>\n<p>\u76ee\u524d\uff0c<span class=\"xintheme_tag_link\">\u72fc\u75ae\u6027\u80be\u708e<\/span>\u4e3b\u8981\u4f9d\u8d56\u6fc0\u7d20\u548c\u514d\u75ab\u6291\u5236\u5242\u6cbb\u7597\uff0c\u867d\u80fd\u63a7\u5236\u90e8\u5206\u60a3\u8005\u75c5\u60c5\uff0c\u4f46\u957f\u671f\u7528\u836f\u526f\u4f5c\u7528\u660e\u663e\uff0c\u4e14\u4ecd\u6709\u4e0d\u5c11\u60a3\u8005\u7597\u6548\u6709\u9650\u3002\u968f\u7740\u7814\u7a76\u4e0d\u65ad\u6df1\u5165\uff0c\u5177\u6709\u514d\u75ab\u8c03\u8282\u4f5c\u7528\u7684\u5e72\u7ec6\u80de\u7597\u6cd5\u9010\u6e10\u53d7\u5230\u5173\u6ce8\uff0c\u4e3a\u72fc\u75ae\u6027\u80be\u708e\u6cbb\u7597\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8def\u3002<\/p>\n<p><strong>\u672c\u6587\u5c06\u7ed3\u5408\u6700\u65b0\u7814\u7a76\u8fdb\u5c55\uff0c\u68b3\u74062025\u5e741\u6708\u81f312\u6708<span class=\"xintheme_tag_link\">\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e<\/span>\u7684\u4e34\u5e8a\u63a2\u7d22\u4e0e\u5173\u952e\u8fdb\u5c55\uff0c\u5e2e\u52a9\u8bfb\u8005\u4e86\u89e3\u8fd9\u4e00\u9886\u57df\u7684\u6700\u65b0\u52a8\u6001\u3002<\/strong><\/p>\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" loading=\"lazy\" width=\"1200\" height=\"630\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2026\/01\/20260126171222-69772ff6d1f22.png\" alt=\"2025\u5e741-12\u6708\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55\u6c47\u603b\" class=\"wp-image-58683\" style=\"width:764px;height:auto\" title=\"2025\u5e741-12\u6708\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55\u6c47\u603b\"><\/figure>\n<p><button type=\"button\" id=\"ftwp-trigger\" class=\"ftwp-shape-round ftwp-border-medium\" title=\"click To Maximize The Table Of Contents\"><span class=\"ftwp-trigger-icon ftwp-icon-number\"><\/span><\/button><\/p>\n<nav id=\"ftwp-contents\" class=\"ftwp-shape-square ftwp-border-medium\">\n<header id=\"ftwp-header\"><span id=\"ftwp-header-control\" class=\"ftwp-icon-number\"><\/span><button type=\"button\" id=\"ftwp-header-minimize\" class=\"ftwp-icon-expand\" aria-labelledby=\"ftwp-header-title\" aria-label=\"Expand or collapse\"><\/button><\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_79_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewbox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewbox=\"0 0 24 24\" version=\"1.2\" baseprofile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' ><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html\/#Contents\" >Contents<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html\/#2025%E5%B9%B41-12%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95%E6%B1%87%E6%80%BB\" >2025\u5e741-12\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u4e34\u5e8a\u8fdb\u5c55\u6c47\u603b<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html\/#2025%E5%B9%B41%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\" >2025\u5e741\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html\/#2025%E5%B9%B43%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\" >2025\u5e743\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html\/#2025%E5%B9%B47%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\" >2025\u5e747\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html\/#2025%E5%B9%B48%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\" >2025\u5e748\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html\/#2025%E5%B9%B410%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\" >2025\u5e7410\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html\/#2025%E5%B9%B411%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\" >2025\u5e7411\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html\/#2025%E5%B9%B4%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E4%B8%B4%E5%BA%8A%E6%80%BB%E7%BB%93\" >2025\u5e74\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u4e34\u5e8a\u603b\u7ed3<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21364.html\/#%E7%BB%93%E8%AF%AD\" >concluding remarks<\/a><\/li><\/ul><\/nav><\/div>\n<h3 id=\"ftwp-header-title\"><span class=\"ez-toc-section\" id=\"Contents\"><\/span>Contents<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<\/header>\n<ol id=\"ftwp-list\" class=\"ftwp-liststyle-decimal ftwp-effect-bounce-to-right ftwp-list-nest ftwp-strong-first ftwp-colexp ftwp-colexp-icon\">\n<li class=\"ftwp-item ftwp-has-sub ftwp-expand\"><button type=\"button\" aria-label=\"Expand or collapse\" class=\"ftwp-icon-expand\"><\/button><span class=\"ftwp-text\">2025\u5e741-12\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u4e34\u5e8a\u8fdb\u5c55\u6c47\u603b<\/span>\n<ol class=\"ftwp-sub\">\n<li class=\"ftwp-item\"><span class=\"ftwp-text\">2025\u5e741\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/span><\/li>\n<li class=\"ftwp-item\"><span class=\"ftwp-text\">2025\u5e743\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/span><\/li>\n<li class=\"ftwp-item\"><span class=\"ftwp-text\">2025\u5e747\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/span><\/li>\n<li class=\"ftwp-item\"><span class=\"ftwp-text\">2025\u5e748\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/span><\/li>\n<li class=\"ftwp-item\"><span class=\"ftwp-text\">2025\u5e7410\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/span><\/li>\n<li class=\"ftwp-item\"><span class=\"ftwp-text\">2025\u5e7411\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/span><\/li>\n<\/ol>\n<\/li>\n<li class=\"ftwp-item\"><span class=\"ftwp-text\">2025\u5e74\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u4e34\u5e8a\u603b\u7ed3<\/span><\/li>\n<li class=\"ftwp-item\"><span class=\"ftwp-text\">concluding remarks<\/span><\/li>\n<\/ol>\n<\/nav>\n<h2 id=\"ftoc-heading-1\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"2025%E5%B9%B41-12%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95%E6%B1%87%E6%80%BB\"><\/span><mark style=\"color:#0092ec\" class=\"has-inline-color\"><strong>2025\u5e741-12\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u4e34\u5e8a\u8fdb\u5c55\u6c47\u603b<\/strong><\/mark><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3 id=\"ftoc-heading-2\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"2025%E5%B9%B41%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\"><\/span><mark style=\"color:#0091eb\" class=\"has-inline-color\"><strong>2025\u5e741\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/strong><\/mark><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>1\u670821\u65e5\uff0c\u7f8e\u56fdCentury Therapeutics\u516c\u53f8\u542f\u52a8\u4e86\u4e00\u9879\u7531\u7814\u7a76\u8005\u53d1\u8d77\u7684I\/II\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08CARAMEL\u8bd5\u9a8c\uff09\uff0c\u8bc4\u4f30\u5176iPSC\u884d\u751fCD19\u9776\u5411NK\u7ec6\u80de\u7597\u6cd5CNTY-101\u5728B\u7ec6\u80de\u4ecb\u5bfc\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u4e2d\u7684\u7597\u6548\uff0c\u5176\u4e2d\u5305\u62ec<strong>\u72fc\u75ae\u6027\u80be\u708e\uff08LN\uff09<\/strong>The<sup>[1]<\/sup><\/p>\n<p>\u8be5\u8bd5\u9a8c\u7531\u57c3\u5c14\u5170\u6839-\u7ebd\u4f26\u5821\u5927\u5b66Schett\/Mackensen\u56e2\u961f\u7275\u5934\uff0c\u662f\u9996\u6b21\u8bc4\u4f30\u540c\u79cd\u5f02\u4f53iPSC\u884d\u751fNK\u7ec6\u80de\u7528\u4e8eLN\u548c\u5176\u4ed6\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u7814\u7a76\u3002<\/p>\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" loading=\"lazy\" width=\"1337\" height=\"887\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2026\/01\/20260126171223-69772ff76d047.png\" alt=\"\u4e16\u7eaa\u6cbb\u7597\u516c\u53f8\u5ba3\u5e03\u542f\u52a8\u4e00\u9879\u7531\u7814\u7a76\u8005\u53d1\u8d77\u76841\/2\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u7814\u7a76\u5176iPSC\u884d\u751fiNK\u7ec6\u80de\u7597\u6cd5CNTY-101\u5728\u6cbb\u7597B\u7ec6\u80de\u4ecb\u5bfc\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u65b9\u9762\u7684\u7597\u6548\uff0c\u8be5\u8bd5\u9a8c\u7531\u56fd\u9645\u77e5\u540d\u610f\u89c1\u9886\u8896\u8d5e\u52a9\u3002\" class=\"wp-image-58705\" style=\"width:664px;height:auto\" title=\"\u4e16\u7eaa\u6cbb\u7597\u516c\u53f8\u5ba3\u5e03\u542f\u52a8\u4e00\u9879\u7531\u7814\u7a76\u8005\u53d1\u8d77\u76841\/2\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u7814\u7a76\u5176iPSC\u884d\u751fiNK\u7ec6\u80de\u7597\u6cd5CNTY-101\u5728\u6cbb\u7597B\u7ec6\u80de\u4ecb\u5bfc\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u65b9\u9762\u7684\u7597\u6548\uff0c\u8be5\u8bd5\u9a8c\u7531\u56fd\u9645\u77e5\u540d\u610f\u89c1\u9886\u8896\u8d5e\u52a9\u3002\"><\/figure>\n<p>CNTY-101\u4f5c\u4e3a\u4e00\u79cd\u201c\u5373\u7528\u578b\u201d\u5e72\u7ec6\u80de\u884d\u751f\u7ec6\u80de\u7597\u6cd5\uff0c\u7ed3\u5408Allo-Evasion\u2122\u6280\u672f\uff0c\u53ef\u7cbe\u51c6\u8c03\u63a7\u836f\u7269\u66b4\u9732\uff0c\u5c55\u73b0\u51fa<strong>\u663e\u8457\u7684\u6297B\u7ec6\u80de\u6d3b\u6027\u548c\u826f\u597d\u5b89\u5168\u6027<\/strong>\u3002\u7814\u7a76\u8005\u6307\u51fa\uff0c\u8be5\u7597\u6cd5\u53ef\u9776\u5411\u8fc7\u5ea6\u6d3b\u5316\u7684B\u7ec6\u80de\uff0c\u4ece\u800c\u6539\u5584LN\u76f8\u5173\u80be\u810f\u708e\u75c7\uff0c\u6f5c\u529b\u5de8\u5927\uff0c\u4e14\u53ef\u5728\u95e8\u8bca\u6761\u4ef6\u4e0b\u7ed9\u836f\u3002<\/p>\n<p>\u6b64\u6b21\u8bd5\u9a8c\u5c06\u8865\u5145Century\u516c\u53f8\u6b63\u5728\u8fdb\u884c\u7684I\u671fCALiPSO-1\u8bd5\u9a8c\u6570\u636e\uff0c\u4e3a\u5e72\u7ec6\u80de\u884d\u751fNK\u7ec6\u80de\u7597\u6cd5\u5728\u72fc\u75ae\u6027\u80be\u708e\u4e2d\u7684\u5e94\u7528\u63d0\u4f9b\u521d\u6b65\u4e34\u5e8a\u8bc1\u636e\uff0c\u5e76\u63a8\u52a8\u5176\u5411\u66f4\u5e7f\u6cdb\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u9002\u5e94\u75c7\u53d1\u5c55\u3002<\/p>\n<h3 id=\"ftoc-heading-3\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"2025%E5%B9%B43%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\"><\/span><mark style=\"color:#0091eb\" class=\"has-inline-color\"><strong>2025\u5e743\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/strong><\/mark><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>3\u67083\u65e5\uff0c\u7a7a\u519b\u519b\u533b\u5927\u5b66\u897f\u4eac\u533b\u9662\u5728\u300aBMC\u80be\u810f\u75c5\u5b66\u300b\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u540d\u4e3a\u300a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u5728\u6162\u6027\u80be\u810f\u75c5\u4e2d\u7684\u514d\u75ab\u8c03\u8282\u4f5c\u7528\uff1a\u6587\u732e\u7efc\u8ff0\u300b\u7684\u7814\u7a76\u6210\u679c\uff0c\u5176\u4e2d\u7cfb\u7edf\u68b3\u7406\u4e86\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\uff08LN\uff09\u7684\u8fdb\u5c55\u4e0e\u6f5c\u529b\u3002<sup>[2]<\/sup><\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"976\" height=\"461\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2026\/01\/20260126171223-69772ff7d928f.png\" alt=\"\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u5728\u6162\u6027\u80be\u810f\u75c5\u4e2d\u7684\u514d\u75ab\u8c03\u8282\u4f5c\u7528\uff1a\u6587\u732e\u7efc\u8ff0\" class=\"wp-image-58688\" title=\"\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u7597\u6cd5\u5728\u6162\u6027\u80be\u810f\u75c5\u4e2d\u7684\u514d\u75ab\u8c03\u8282\u4f5c\u7528\uff1a\u6587\u732e\u7efc\u8ff0\"><figcaption><\/figcaption><\/figure>\n<p>\u7814\u7a76\u6307\u51fa\uff0cMSCs\u5728LN\u6cbb\u7597\u4e2d\u5c55\u73b0\u51fa\u4fee\u590d\u4e0e\u518d\u751f\u7684\u53cc\u91cd\u4ef7\u503c\u3002\u4e34\u5e8a\u7ed3\u679c\u663e\u793a\uff0c<strong>\u8f93\u6ce8MSCs\u80fd\u591f\u6539\u5584\u591a\u9879\u80be\u529f\u80fd\u6307\u6807\uff0c\u5982\u51cf\u5c11\u86cb\u767d\u5c3f\u3001\u7a33\u5b9a\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff08GFR\uff09\uff0c\u5e76\u964d\u4f4e\u8840\u6e05\u808c\u9150\u4e0e\u8840\u5c3f\u7d20\u6c2e\u6c34\u5e73\uff0c\u540c\u65f6\u63d0\u5347\u8840\u6e05\u767d\u86cb\u767d<\/strong>\u3002\u5728\u514d\u75ab\u8c03\u8282\u65b9\u9762\uff0cMSCs\u53ef\u589e\u52a0\u8c03\u8282\u6027T\u7ec6\u80de\uff08Tregs\uff09\u6bd4\u4f8b\uff0c\u6291\u5236B\u7ec6\u80de\u4e0e\u81ea\u7136\u6740\u4f24T\uff08NKT\uff09\u7ec6\u80de\u6d3b\u6027\uff0c\u4ece\u800c\u5e2e\u52a9\u5e73\u8861\u8fc7\u5ea6\u6d3b\u8dc3\u7684\u514d\u75ab\u53cd\u5e94\u3002<\/p>\n<p>\u4ece\u4e34\u5e8a\u6548\u679c\u770b\uff0c<strong>\u5927\u591a\u6570LN\u60a3\u8005\u5728MSCs\u8f93\u6ce8\u540e1\u81f39\u4e2a\u6708\u5185\u5c3f\u86cb\u767d\u5373\u660e\u663e\u4e0b\u964d\uff0c\u90e8\u5206\u6539\u5584\u53ef\u6301\u7eed\u4e00\u5e74\u4ee5\u4e0a<\/strong>\uff1b\u4e14\u80be\u529f\u80fd\u76f8\u5bf9\u8f83\u597d\uff08GFR \u226530 ml\/min\/1.73 m\u00b2\uff09\u7684\u60a3\u8005\u5f80\u5f80\u83b7\u76ca\u66f4\u663e\u8457\u3001\u66f4\u6301\u4e45\u3002\u5728\u5b89\u5168\u6027\u65b9\u9762\uff0c\u8be5\u7597\u6cd5\u6574\u4f53\u8010\u53d7\u826f\u597d\uff0c\u5e38\u89c1\u53cd\u5e94\u4e3b\u8981\u4e3a\u77ed\u6682\u53d1\u70ed\u6216\u8f93\u6ce8\u5c40\u90e8\u4e0d\u9002\uff0c\u672a\u89c1\u4e25\u91cd\u6076\u6027\u4e8b\u4ef6\u62a5\u544a\u3002<\/p>\n<p>\u603b\u4f53\u800c\u8a00\uff0c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u4e3a\u72fc\u75ae\u6027\u80be\u708e\u63d0\u4f9b\u4e86\u4e00\u79cd\u5177\u6709\u80be\u810f\u4fdd\u62a4\u6f5c\u529b\u7684\u8f85\u52a9\u6cbb\u7597\u9009\u62e9\uff0c\u5c24\u5176\u9002\u7528\u4e8e\u75be\u75c5\u65e9\u671f\u6216\u5bf9\u5e38\u89c4\u514d\u75ab\u6cbb\u7597\u6548\u679c\u4e0d\u4f73\u7684\u60a3\u8005\uff0c\u5177\u5907\u8f83\u597d\u7684\u4e34\u5e8a\u5b89\u5168\u6027\u4e0e\u5e94\u7528\u524d\u666f\u3002<\/p>\n<p>3\u670812\u65e5\uff0c\u5357\u4eac\u9f13\u697c\u533b\u9662\u7275\u5934\u5728\u300aBMJ\u300b\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u540d\u4e3a\u300a\u4ee3\u8c22\u7ec4\u5b66\u5206\u6790\u8868\u660e\uff0c\u786b\u80fa\u7d20\u5355\u78f7\u9178\u916f\u53ef\u80fd\u662f\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\uff08SLE\uff09\u60a3\u8005\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\u7597\u6548\u7684\u6f5c\u5728\u6807\u5fd7\u7269\u300b\u7684\u7814\u7a76\u6210\u679c\u3002<sup>[3]<\/sup><\/p>\n<p>\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4e86\u4e00\u4e9b\u4ee3\u8c22\u751f\u7269\u6807\u5fd7\u7269\uff0c\u8fd9\u4e9b\u6807\u5fd7\u7269\u53ef\u80fd\u4e0e\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\uff08SLE\uff09\u00a0\u60a3\u8005\u63a5\u53d7\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\uff08MSCT\uff09\u6cbb\u7597\u7684\u6210\u529f\u76f8\u5173\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"1569\" height=\"267\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2026\/01\/20260126171224-69772ff804cd1.png\" alt=\"\u4ee3\u8c22\u7ec4\u5b66\u5206\u6790\u8868\u660e\uff0c\u786b\u80fa\u7d20\u5355\u78f7\u9178\u916f\u53ef\u80fd\u662f\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\uff08SLE\uff09\u60a3\u8005\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\u7597\u6548\u7684\u6f5c\u5728\u6807\u5fd7\u7269\u3002\" class=\"wp-image-58701\" title=\"\u4ee3\u8c22\u7ec4\u5b66\u5206\u6790\u8868\u660e\uff0c\u786b\u80fa\u7d20\u5355\u78f7\u9178\u916f\u53ef\u80fd\u662f\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\uff08SLE\uff09\u60a3\u8005\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u79fb\u690d\u7597\u6548\u7684\u6f5c\u5728\u6807\u5fd7\u7269\u3002\"><figcaption><\/figcaption><\/figure>\n<p>\u7814\u7a76\u4e2d\uff0c20\u540dSLE\u60a3\u8005\u5728\u63a5\u53d7MSCT\u6cbb\u7597\u524d\u540e\u91c7\u96c6\u8840\u6d46\u6837\u672c\uff0c\u5e76\u5728\u6cbb\u7597\u540e180\u5929\u8fdb\u884c\u968f\u8bbf\u3002<\/p>\n<p>\u7ed3\u679c\u663e\u793a\uff0c\u60a3\u8005\u5728\u6cbb\u7597\u540e\u51fa\u73b0\u660e\u663e\u4e34\u5e8a\u6539\u5584\uff0c\u5305\u62ec<strong>\u75be\u75c5\u6d3b\u52a8\u8bc4\u5206\u4e0b\u964d\u3001\u5c3f\u86cb\u767d\u548c\u7ea2\u7ec6\u80de\u6c89\u964d\u7387\u964d\u4f4e\uff0c\u4ee5\u53ca\u8865\u4f53C3\/C4\u3001\u8840\u7ea2\u86cb\u767d\u548c\u8840\u5c0f\u677f\u6c34\u5e73\u5347\u9ad8<\/strong>The<\/p>\n<p>\u4ee3\u8c22\u7ec4\u5206\u6790\u53d1\u73b0\uff0c\u5171\u68c0\u6d4b\u523018,121\u79cd\u4ee3\u8c22\u7269\uff0c\u5176\u4e2d1,152\u79cd\u5728\u6cbb\u7597\u540e\u53d1\u751f\u663e\u8457\u53d8\u5316\u3002\u5c24\u5176\u662f<strong>\u786b\u80fa\u7d20\u5355\u78f7\u9178\u916f\uff08TMP\uff09\u548c\u79ef\u96ea\u8349\u82f7\u6c34\u5e73\u5347\u9ad8<\/strong>\uff0c\u4e0e\u4e34\u5e8a\u6539\u5584\u5bc6\u5207\u76f8\u5173\u3002TMP\u6c34\u5e73\u5347\u9ad8\u7ea635%\u53ef\u9884\u6d4b\u826f\u597d\u7684\u6cbb\u7597\u53cd\u5e94\uff0c\u63d0\u793a\u5176\u53ef\u80fd\u4f5c\u4e3a<strong>MSCT\u7597\u6548\u7684\u6f5c\u5728\u751f\u7269\u6807\u5fd7\u7269<\/strong>The<\/p>\n<p>\u8be5\u7814\u7a76\u4e3aSLE\u60a3\u8005\u7684\u5e72\u7ec6\u80de\u6cbb\u7597\u63d0\u4f9b\u4e86<strong>\u53ef\u91cf\u5316\u7684\u7597\u6548\u6307\u6807<\/strong>\uff0c\u4e3a\u4e34\u5e8a\u5b9e\u8df5\u548c\u672a\u6765\u7814\u7a76\u63d0\u4f9b\u4e86\u53c2\u8003\u4f9d\u636e\u3002\u00a0<\/p>\n<h3 id=\"ftoc-heading-4\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"2025%E5%B9%B47%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\"><\/span><mark style=\"color:#0091eb\" class=\"has-inline-color\"><strong>2025\u5e747\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/strong><\/mark><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>7\u67081\u65e5\uff0c\u5357\u901a\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u533b\u9662\u7275\u5934\u5728\u300aLife Sciences\u300b\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u540d\u4e3a\u300a\u60a3\u8005\u5c3f\u6db2\u6765\u6e90\u7684\u5e72\u7ec6\u80de\u901a\u8fc7CXCL14\u4f9d\u8d56\u6027\u65b9\u5f0f\u8c03\u8282\u5de8\u566c\u7ec6\u80de\u6781\u5316\uff0c\u4ece\u800c\u7f13\u89e3\u72fc\u75ae\u6027\u80be\u708e\u300b\u7684\u7814\u7a76\u6210\u679c\u3002<sup>[4]<\/sup><\/p>\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" loading=\"lazy\" width=\"623\" height=\"502\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2026\/01\/20260126171224-69772ff8353f4.png\" alt=\"\u60a3\u8005\u5c3f\u6db2\u6765\u6e90\u7684\u5e72\u7ec6\u80de\u901a\u8fc7CXCL14\u4f9d\u8d56\u6027\u65b9\u5f0f\u8c03\u8282\u5de8\u566c\u7ec6\u80de\u6781\u5316\uff0c\u4ece\u800c\u7f13\u89e3\u72fc\u75ae\u6027\u80be\u708e\" class=\"wp-image-58687\" style=\"width:623px;height:auto\" title=\"\u60a3\u8005\u5c3f\u6db2\u6765\u6e90\u7684\u5e72\u7ec6\u80de\u901a\u8fc7CXCL14\u4f9d\u8d56\u6027\u65b9\u5f0f\u8c03\u8282\u5de8\u566c\u7ec6\u80de\u6781\u5316\uff0c\u4ece\u800c\u7f13\u89e3\u72fc\u75ae\u6027\u80be\u708e\"><\/figure>\n<p>\u7814\u7a76\u7cfb\u7edf\u8bc4\u4f30\u4e86\u5c3f\u6e90\u6027\u5e72\u7ec6\u80de\uff08USC\uff09\u5728\u72fc\u75ae\u6027\u80be\u708e\u6cbb\u7597\u4e2d\u7684\u6f5c\u529b\uff0c\u5e76\u63ed\u793a\u4e86\u5176\u5173\u952e\u514d\u75ab\u8c03\u8282\u673a\u5236\u3002<\/p>\n<p>\u7814\u7a76\u53d1\u73b0\uff0c\u4e0e\u5065\u5eb7\u4eba\u53ca\u65e0\u80be\u635f\u5bb3\u7684SLE\u60a3\u8005\u6765\u6e90USC\u76f8\u6bd4\uff0c<strong>\u72fc\u75ae\u6027\u80be\u708e\u60a3\u8005\u81ea\u8eab\u6765\u6e90\u7684USC\uff08LN-USC\uff09\u5177\u6709\u66f4\u5f3a\u7684\u589e\u6b96\u80fd\u529b\u548c\u66f4\u7a33\u5b9a\u7684\u7ec6\u80de\u72b6\u6001<\/strong>\uff0c\u5e76\u53ef\u663e\u8457\u8c03\u8282\u5f02\u5e38\u514d\u75ab\u53cd\u5e94\u3002\u52a8\u7269\u5b9e\u9a8c\u663e\u793a\uff0cLN-USC\u5728MRL\/lpr\u72fc\u75ae\u6027\u80be\u708e\u5c0f\u9f20\u6a21\u578b\u4e2d<strong>\u663e\u8457\u6539\u5584\u75be\u75c5\u8868\u73b0\uff0c\u7597\u6548\u4f18\u4e8e\u5176\u4ed6\u6765\u6e90\u7684USC<\/strong>The<\/p>\n<p>\u673a\u5236\u7814\u7a76\u8fdb\u4e00\u6b65\u8868\u660e\uff0c<strong>LN-USC\u53ef\u901a\u8fc7CXCL14\u4f9d\u8d56\u6027\u9014\u5f84\u6291\u5236\u4fc3\u708e\u6027M1\u578b\u5de8\u566c\u7ec6\u80de\u6781\u5316<\/strong>\uff0c\u540c\u65f6\u4fc3\u8fdb\u514d\u75ab\u8010\u53d7\u76f8\u5173\u7ec6\u80de\u7684\u6062\u590d\uff1b\u5f53CXCL14\u88ab\u6572\u4f4e\u540e\uff0c\u5176\u514d\u75ab\u8c03\u8282\u4f5c\u7528\u548c\u6cbb\u7597\u6548\u679c\u660e\u663e\u51cf\u5f31\u3002<\/p>\n<p>\u603b\u4f53\u6765\u770b\uff0c\u8be5\u7814\u7a76\u8868\u660e\uff0c\u5c3f\u6e90\u6027\u5e72\u7ec6\u80de\u4e0d\u4ec5\u53ef\u901a\u8fc7\u65e0\u521b\u65b9\u5f0f\u83b7\u53d6\uff0c\u8fd8\u5177\u5907\u4f5c\u4e3a\u81ea\u4f53\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u7684\u5b9e\u9645\u53ef\u884c\u6027\u548c\u660e\u786e\u751f\u7269\u5b66\u57fa\u7840\uff0c\u4e3a\u672a\u6765\u66f4\u5b89\u5168\u3001\u4e2a\u4f53\u5316\u7684\u5e72\u7ec6\u80de\u6cbb\u7597\u7b56\u7565\u63d0\u4f9b\u4e86\u65b0\u7684\u65b9\u5411\u3002<\/p>\n<h3 id=\"ftoc-heading-5\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"2025%E5%B9%B48%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\"><\/span><mark style=\"color:#0091eb\" class=\"has-inline-color\"><strong>2025\u5e748\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/strong><\/mark><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>8\u670826\u65e5\uff0c\u6d59\u6c5f\u7701\u4eba\u6c11\u533b\u9662\u7275\u5934\u5728\u300a\u4e16\u754c\u5e72\u7ec6\u80de\u6742\u5fd7\u300b\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u540d\u4e3a\u300a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u7684\u8fdb\u5c55\u300b\u7684\u7814\u7a76\u6210\u679c\u3002<sup>[5]<\/sup><\/p>\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"710\" height=\"564\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2026\/01\/20260126171224-69772ff8462cd.png\" alt=\"\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u7684\u8fdb\u5c55\" class=\"wp-image-58685\" title=\"\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u7684\u8fdb\u5c55\"><\/figure>\n<p>\u7814\u7a76\u8868\u660e\uff0c\u591a\u9879\u7814\u7a76\u663e\u793a\uff0c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u7597\u6cd5\u4e3a\u96be\u6cbb\u6027\u72fc\u75ae\u6027\u80be\u708e\u63d0\u4f9b\u4e86\u65b0\u7684\u6cbb\u7597\u53ef\u80fd\u3002<\/p>\n<p>\u7efc\u5408\u65e2\u5f80\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\uff0c\u65e0\u8bba\u6765\u6e90\u4e8e\u9aa8\u9ad3\u3001\u8110\u5e26\u8fd8\u662f\u8102\u80aa\u7ec4\u7ec7\u7684MSC\u6cbb\u7597\uff0c\u5747\u5728\u591a\u6570\u60a3\u8005\u4e2d\u8868\u73b0\u51fa\u660e\u786e\u7684\u4e34\u5e8a\u83b7\u76ca\u3002\u6cbb\u7597\u540e\uff0c\u60a3\u8005\u7684<strong>\u75be\u75c5\u6d3b\u52a8\u5ea6\u8bc4\u5206\uff08SLEDAI\uff09\u663e\u8457\u4e0b\u964d\uff0c\u81ea\u8eab\u6297\u4f53\uff08\u6297dsDNA\uff09\u6c34\u5e73\u964d\u4f4e\uff0c\u86cb\u767d\u5c3f\u660e\u663e\u51cf\u5c11\uff0c\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff08eGFR\uff09\u5f97\u5230\u6539\u5584\u6216\u7a33\u5b9a<\/strong>\uff0c\u63d0\u793aMSC\u7597\u6cd5\u5728\u63a7\u5236\u7cfb\u7edf\u6027\u708e\u75c7\u548c\u6539\u5584\u80be\u529f\u80fd\u65b9\u9762\u5177\u6709\u79ef\u6781\u4f5c\u7528\u3002<\/p>\n<p>\u5728\u968f\u8bbf\u7814\u7a76\u4e2d\uff0c<strong>\u90e8\u5206\u96be\u6cbb\u6027\u72fc\u75ae\u6027\u80be\u708e\u60a3\u8005\u53ef\u83b7\u5f97\u6301\u7eed\u7684\u4e34\u5e8a\u7f13\u89e3<\/strong>\uff0c1\uff5e4\u5e74\u968f\u8bbf\u663e\u793a\u5b8c\u5168\u6216\u90e8\u5206\u7f13\u89e3\u7387\u9010\u6b65\u63d0\u9ad8\uff0c\u590d\u53d1\u7387\u5904\u4e8e\u53ef\u63a7\u8303\u56f4\uff0c\u6574\u4f53\u751f\u5b58\u7387\u4fdd\u6301\u5728\u8f83\u9ad8\u6c34\u5e73\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c<strong>MSC\u6cbb\u7597\u5728\u65e2\u5f80\u591a\u7ebf\u514d\u75ab\u6291\u5236\u5931\u8d25\u7684\u60a3\u8005\u4e2d\u4ecd\u53ef\u53d1\u6325\u7597\u6548<\/strong>\uff0c\u663e\u793a\u51fa\u5176\u4f5c\u4e3a\u201c\u8865\u6551\u6027\u6216\u8054\u5408\u6cbb\u7597\u624b\u6bb5\u201d\u7684\u72ec\u7279\u4ef7\u503c\u3002<\/p>\n<p>\u5b89\u5168\u6027\u65b9\u9762\uff0c\u73b0\u6709\u4e34\u5e8a\u8bd5\u9a8c\u666e\u904d\u8ba4\u4e3aMSC\u7597\u6cd5\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u89c2\u5bdf\u5230\u660e\u786e\u7684\u79fb\u690d\u76f8\u5173\u4e25\u91cd\u4e0d\u826f\u53cd\u5e94\u3001\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\u6216\u80bf\u7624\u98ce\u9669\u3002\u5df2\u62a5\u9053\u7684\u4e0d\u826f\u4e8b\u4ef6\u591a\u4e0e\u57fa\u7840\u514d\u75ab\u6291\u5236\u6cbb\u7597\u76f8\u5173\uff0c\u800c\u975eMSC\u672c\u8eab\u3002<\/p>\n<p>\u603b\u4f53\u6765\u770b\uff0c\u73b0\u6709\u8bc1\u636e\u8868\u660e\uff0c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u80fd\u591f\u5728\u4e00\u5b9a\u6bd4\u4f8b\u7684\u72fc\u75ae\u6027\u80be\u708e\u60a3\u8005\u4e2d\u6709\u6548\u964d\u4f4e\u75be\u75c5\u6d3b\u52a8\u5ea6\u3001\u6539\u5584\u80be\u810f\u6307\u6807\u5e76\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\uff0c\u5c24\u5176\u4e3a\u4f20\u7edf\u6cbb\u7597\u6548\u679c\u4e0d\u4f73\u7684\u60a3\u8005\u63d0\u4f9b\u4e86\u65b0\u7684\u6cbb\u7597\u5e0c\u671b\u3002\u968f\u7740\u7ed9\u836f\u65b9\u6848\u3001\u7ec6\u80de\u6765\u6e90\u53ca\u60a3\u8005\u7b5b\u9009\u7b56\u7565\u7684\u8fdb\u4e00\u6b65\u4f18\u5316\uff0cMSC\u7597\u6cd5\u6709\u671b\u5728\u72fc\u75ae\u6027\u80be\u708e\u7684\u7efc\u5408\u6cbb\u7597\u4f53\u7cfb\u4e2d\u53d1\u6325\u66f4\u52a0\u91cd\u8981\u7684\u4f5c\u7528\u3002<\/p>\n<h3 id=\"ftoc-heading-6\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"2025%E5%B9%B410%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\"><\/span><mark style=\"color:#0091eb\" class=\"has-inline-color\"><strong>2025\u5e7410\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/strong><\/mark><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>10\u670810\u65e5\uff0c\u5357\u4eac\u9f13\u697c\u533b\u9662\u7275\u5934\u5728\u300a\u7eb3\u7c73\u751f\u7269\u6280\u672f\u6742\u5fd7\u300b\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u540d\u4e3a\u300a\u5de5\u7a0b\u5316\u5916\u6ccc\u4f53\u901a\u8fc7\u8c03\u8282\u6d3b\u6027\u6c27\u548c\u514d\u75ab\u6291\u5236\u4f5c\u7528\u6539\u5584\u72fc\u75ae\u6027\u80be\u708e\u300b\u7684\u7814\u7a76\u6210\u679c\u3002<sup>[6]<\/sup><\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"1073\" height=\"470\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2026\/01\/20260126171224-69772ff858db2.png\" alt=\"\u5de5\u7a0b\u5316\u5916\u6ccc\u4f53\u901a\u8fc7\u8c03\u8282\u6d3b\u6027\u6c27\u548c\u514d\u75ab\u6291\u5236\u4f5c\u7528\u6539\u5584\u72fc\u75ae\u6027\u80be\u708e\" class=\"wp-image-58691\" title=\"\u5de5\u7a0b\u5316\u5916\u6ccc\u4f53\u901a\u8fc7\u8c03\u8282\u6d3b\u6027\u6c27\u548c\u514d\u75ab\u6291\u5236\u4f5c\u7528\u6539\u5584\u72fc\u75ae\u6027\u80be\u708e\"><figcaption><\/figcaption><\/figure>\n<p>\u7814\u7a76\u56e2\u961f\u5f00\u53d1\u4e86\u4e00\u79cd\u5de5\u7a0b\u5316\u5916\u6ccc\u4f53\uff08MEX\uff09\u7eb3\u7c73\u8f7d\u4f53\u2014\u2014CEX@Rapa\uff0c\u901a\u8fc7\u5c06\u4e8c\u6c27\u5316\u94c8\uff08Ce\uff09\u7eb3\u7c73\u9897\u7c92\u5076\u8054\u5230\u8f7d\u96f7\u5e15\u9709\u7d20\u7684MEX\u4e0a\u5236\u6210\u3002<\/p>\n<p>\u8fd9\u79cd\u7eb3\u7c73\u6742\u5316\u7269\u6bd2\u6027\u6781\u4f4e\uff0c\u8f7d\u836f\u6548\u7387\u9ad8\uff0c\u6613\u88ab\u7ec6\u80de\u5438\u6536\uff0c\u5e76\u5177\u5907\u6297\u6c27\u5316\u3001\u6297\u635f\u4f24\u53ca\u6297\u708e\u80fd\u529b\u3002\u5168\u8eab\u7ed9\u836f\u540e\uff0cCEX@Rapa\u5728\u80be\u810f\u708e\u75c7\u90e8\u4f4d\u5bcc\u96c6\uff0c\u51cf\u8f7b\u8fc7\u5ea6\u514d\u75ab\u53cd\u5e94\u5e76\u4fc3\u8fdb\u80be\u810f\u4fee\u590d\u3002<strong>\u7814\u7a76\u663e\u793a\uff0cMEX\u3001Ce\u7eb3\u7c73\u9897\u7c92\u548c\u96f7\u5e15\u9709\u7d20\u7684\u534f\u540c\u4f5c\u7528\u53ef\u663e\u8457\u7f13\u89e3\u72fc\u75ae\u6027\u80be\u708e\u75c7\u72b6<\/strong>The<\/p>\n<p>\u8be5\u7814\u7a76\u8868\u660e\uff0cCe\u56fa\u5b9a\u5316MEX\u4f5c\u4e3a\u4e00\u79cd\u5177\u5907\u6d3b\u6027\u6c27\u8c03\u8282\u548c\u514d\u75ab\u8c03\u63a7\u80fd\u529b\u7684\u589e\u5f3a\u578b\u7eb3\u7c73\u836f\u7269\u8f7d\u4f53\uff0c\u5728\u72fc\u75ae\u6027\u80be\u708e\u53ca\u5176\u4ed6\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u6cbb\u7597\u4e2d\u5177\u6709\u5e7f\u9614\u5e94\u7528\u524d\u666f\u3002<\/p>\n<h3 id=\"ftoc-heading-7\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"2025%E5%B9%B411%E6%9C%88%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E6%9C%80%E6%96%B0%E4%B8%B4%E5%BA%8A%E8%BF%9B%E5%B1%95\"><\/span><mark style=\"color:#0091eb\" class=\"has-inline-color\"><strong>2025\u5e7411\u6708\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u6700\u65b0\u4e34\u5e8a\u8fdb\u5c55<\/strong><\/mark><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>11\u6708\uff0c\u897f\u73ed\u7259\u9a6c\u5fb7\u91cc\u533b\u9662\u7275\u5934\u5728\u300a\u80be\u810f\u56fd\u9645\u62a5\u544a\u300b\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u72fc\u75ae\u6027\u80be\u708e\u60a3\u8005\u63a5\u53d7\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u540e\u7684\u7597\u6548\u89c2\u5bdf\u6210\u679c\u3002<sup>[7]<\/sup><\/p>\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"1253\" height=\"299\" src=\"https:\/\/www.hjtdsm.cn\/wp-content\/uploads\/2026\/01\/20260126171224-69772ff88da49.png\" alt=\"\u72fc\u75ae\u6027\u80be\u708e\u60a3\u8005\u63a5\u53d7\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u540e\uff0c\u5c3d\u7ba1\u5168\u8eab\u75c7\u72b6\u7f13\u89e3\uff0c\u4f46\u80be\u810f\u6d3b\u52a8\u4ecd\u6301\u7eed\u5b58\u5728\" class=\"wp-image-58684\" title=\"\u72fc\u75ae\u6027\u80be\u708e\u60a3\u8005\u63a5\u53d7\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u540e\uff0c\u5c3d\u7ba1\u5168\u8eab\u75c7\u72b6\u7f13\u89e3\uff0c\u4f46\u80be\u810f\u6d3b\u52a8\u4ecd\u6301\u7eed\u5b58\u5728\"><\/figure>\n<p>\u7814\u7a76\u62a5\u9053\u4e862\u4f8b\u91cd\u75c7\u96be\u6cbb\u6027\u72fc\u75ae\u6027\u80be\u708e\uff08LN\uff09\u60a3\u8005\u63a5\u53d7\u81ea\u4f53\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\uff08HSCT\uff09\u540e\u7684\u957f\u671f\u7597\u6548\u89c2\u5bdf\u7ed3\u679c\u3002\u4e24\u540d\u60a3\u8005\u5747\u4e3a\u5e74\u8f7b\u5973\u6027\uff0c\u75c5\u7a0b\u4e2d\u5bf9\u7cd6\u76ae\u8d28\u6fc0\u7d20\u3001\u73af\u78f7\u9170\u80fa\u3001\u5417\u66ff\u9ea6\u8003\u915a\u916f\u3001\u9499\u8c03\u78f7\u9178\u9176\u6291\u5236\u5242\u53ca\u591a\u79cd\u751f\u7269\u5236\u5242\uff08\u5229\u59a5\u6614\u5355\u6297\u3001\u8d1d\u5229\u6728\u5355\u6297\uff09\u6cbb\u7597\u53cd\u5e94\u4e0d\u4f73\uff0c\u5c5e\u4e8e\u5178\u578b\u7684\u96be\u6cbb\u6027LN\u3002<\/p>\n<p>\u5728\u591a\u5b66\u79d1\u8bc4\u4f30\u540e\uff0c\u4e24\u4f8b\u60a3\u8005\u5206\u522b\u4e8e2022\u5e74\u548c2024\u5e74\u63a5\u53d7\u81ea\u4f53HSCT\u3002\u79fb\u690d\u8fc7\u7a0b\u8010\u53d7\u826f\u597d\uff0c\u672a\u51fa\u73b0\u4e25\u91cd\u5e76\u53d1\u75c7\u3002<\/p>\n<p>\u968f\u8bbf\u7ed3\u679c\u663e\u793a\uff0c<strong>\u4e24\u540d\u60a3\u8005\u5747\u5b9e\u73b0\u4e86\u663e\u8457\u7684\u4e34\u5e8a\u548c\u514d\u75ab\u5b66\u7f13\u89e3<\/strong>\uff0c\u8868\u73b0\u4e3a\u80be\u5916\u75c7\u72b6\u6d88\u5931\u3001\u8865\u4f53\u6c34\u5e73\u6062\u590d\u6b63\u5e38\u3001\u6297\u53cc\u94feDNA\u6297\u4f53\u548cANA\u8f6c\u9634\uff0c\u63d0\u793aHSCT\u5728\u201c\u514d\u75ab\u91cd\u7f6e\u201d\u65b9\u9762\u5177\u6709\u660e\u786e\u6548\u679c\u3002<\/p>\n<p>\u7136\u800c\uff0c\u5c3d\u7ba1\u5168\u8eab\u514d\u75ab\u5b66\u6307\u6807\u7a33\u5b9a\uff0c\u80be\u810f\u75c5\u53d8\u5e76\u672a\u5b8c\u5168\u7f13\u89e3\u3002\u79fb\u690d\u540e\u591a\u6b21\u80be\u6d3b\u68c0\u4ecd\u663e\u793aIV\u578b\u6216V\u578b\u72fc\u75ae\u6027\u80be\u708e\u7684\u7ec4\u7ec7\u5b66\u6d3b\u52a8\uff0c\u86cb\u767d\u5c3f\u6301\u7eed\u5b58\u5728\uff08\u7ea64\u20135 g\/24 h\uff09\uff0c\u63d0\u793a\u80be\u810f\u5c40\u90e8\u708e\u75c7\u548c\u7ec4\u7ec7\u635f\u4f24\u4ecd\u7136\u5ef6\u7eed\u3002<\/p>\n<p>\u8be5\u7814\u7a76\u8868\u660e\uff0c\u81ea\u4f53HSCT\u80fd\u591f\u6709\u6548\u8bf1\u5bfc\u7cfb\u7edf\u6027\u514d\u75ab\u7f13\u89e3\uff0c\u4f46\u5bf9\u90e8\u5206\u96be\u6cbb\u6027LN\u60a3\u8005\u800c\u8a00\uff0c\u80be\u810f\u5c40\u90e8\u514d\u75ab\u5931\u8c03\u53ef\u80fd\u65e0\u6cd5\u5b8c\u5168\u88ab\u6e05\u9664\uff0c\u80be\u7ec4\u7ec7\u7684\u4fee\u590d\u660e\u663e\u6ede\u540e\u4e8e\u5168\u8eab\u514d\u75ab\u6062\u590d\u3002\u8fd9\u4e00\u7ed3\u679c\u5f3a\u8c03\u4e86HSCT\u5728\u72fc\u75ae\u6027\u80be\u708e\u4e2d\u7684\u6f5c\u529b\u4e0e\u5c40\u9650\u6027\uff0c\u4e5f\u63d0\u793a\u672a\u6765\u9700\u8981\u9488\u5bf9\u80be\u810f\u5fae\u73af\u5883\u7684\u8054\u5408\u6216\u5e8f\u8d2f\u6cbb\u7597\u7b56\u7565\uff0c\u4ee5\u5b9e\u73b0\u771f\u6b63\u7684\u201c\u80be\u810f\u5b8c\u5168\u7f13\u89e3\u201d\u3002<\/p>\n<h2 id=\"ftoc-heading-8\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"2025%E5%B9%B4%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%8B%BC%E7%96%AE%E6%80%A7%E8%82%BE%E7%82%8E%E4%B8%B4%E5%BA%8A%E6%80%BB%E7%BB%93\"><\/span><mark style=\"color:#0094f0\" class=\"has-inline-color\"><strong>2025\u5e74\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u4e34\u5e8a\u603b\u7ed3<\/strong><\/mark><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u7efc\u4e0a\u6240\u8ff0\uff0c2025\u5e74\u7684\u7814\u7a76\u663e\u793a\uff0c\u5e72\u7ec6\u80de\u53ca\u5176\u884d\u751f\u7597\u6cd5\u5728\u72fc\u75ae\u6027\u80be\u708e\u4e2d\u5c55\u73b0\u51fa\u826f\u597d\u7684\u5b89\u5168\u6027\u548c\u6f5c\u5728\u7597\u6548\u3002\u76f8\u5173\u6cbb\u7597\u53ef\u6539\u5584\u80be\u529f\u80fd\uff0c\u5982\u51cf\u5c11\u86cb\u767d\u5c3f\u3001\u7a33\u5b9a\u6216\u63d0\u5347\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\uff0c\u5e76\u5ef6\u7f13\u80be\u810f\u635f\u4f24\u3002<\/p>\n<p>\u540c\u65f6\uff0c\u5e72\u7ec6\u80de\u7597\u6cd5\u80fd\u591f\u8c03\u8282\u514d\u75ab\u7cfb\u7edf\uff0c\u6291\u5236\u8fc7\u5ea6\u6d3b\u8dc3\u7684B\u7ec6\u80de\uff0c\u589e\u5f3a\u8c03\u8282\u6027T\u7ec6\u80de\u548c\u514d\u75ab\u8010\u53d7\uff0c\u4ece\u800c\u51cf\u8f7b\u708e\u75c7\u53cd\u5e94\u3002\u5bf9\u4e8e\u4f20\u7edf\u514d\u75ab\u6cbb\u7597\u6548\u679c\u6709\u9650\u7684\u60a3\u8005\uff0c\u8fd9\u7c7b\u7597\u6cd5\u4e5f\u663e\u793a\u51fa\u6f5c\u5728\u5e2e\u52a9\u3002<\/p>\n<p>2025\u5e74\u7684\u4e34\u5e8a\u63a2\u7d22\u4e2d\uff0c\u5305\u62eciPSC\u884d\u751fNK\u7ec6\u80de\u3001\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u3001\u5c3f\u6e90\u6027\u5e72\u7ec6\u80de\u3001\u5de5\u7a0b\u5316\u5916\u6ccc\u4f53\u4ee5\u53ca\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u7b49\u591a\u79cd\u7b56\u7565\uff0c\u4e3a\u72fc\u75ae\u6027\u80be\u708e\u6cbb\u7597\u63d0\u4f9b\u4e86\u65b0\u7684\u601d\u8def\u3002<\/p>\n<p>\u603b\u4f53\u800c\u8a00\uff0c\u5e72\u7ec6\u80de\u7597\u6cd5\u4e3a\u72fc\u75ae\u6027\u80be\u708e\u5e26\u6765\u4e86\u5b89\u5168\u3001\u6709\u6548\u7684\u6cbb\u7597\u524d\u666f\uff0c\u6709\u671b\u6210\u4e3a\u672a\u6765\u7efc\u5408\u6cbb\u7597\u7684\u91cd\u8981\u7ec4\u6210\u90e8\u5206\u3002<\/p>\n<h2 id=\"ftoc-heading-9\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E7%BB%93%E8%AF%AD\"><\/span><mark style=\"color:#0092ed\" class=\"has-inline-color\"><strong>concluding remarks<\/strong><\/mark><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u968f\u7740\u7814\u7a76\u7684\u4e0d\u65ad\u6df1\u5165\uff0c\u5e72\u7ec6\u80de\u53ca\u5176\u884d\u751f\u7597\u6cd5\u5728\u72fc\u75ae\u6027\u80be\u708e\u7684\u6cbb\u7597\u4e2d\u663e\u793a\u51fa\u8d8a\u6765\u8d8a\u660e\u786e\u7684\u6f5c\u529b\u3002\u65e0\u8bba\u662f\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u3001iPSC\u884d\u751fNK\u7ec6\u80de\uff0c\u8fd8\u662f\u5de5\u7a0b\u5316\u5916\u6ccc\u4f53\uff0c\u8fd9\u4e9b\u521b\u65b0\u7597\u6cd5\u4e0d\u4ec5\u80fd\u591f\u6539\u5584\u80be\u529f\u80fd\u548c\u86cb\u767d\u5c3f\u6c34\u5e73\uff0c\u8fd8\u80fd\u8c03\u8282\u5f02\u5e38\u514d\u75ab\u53cd\u5e94\uff0c\u4e3a\u4f20\u7edf\u6cbb\u7597\u6548\u679c\u6709\u9650\u7684\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u9009\u62e9\u3002<\/p>\n<p>2025\u5e74\u7684\u4e34\u5e8a\u63a2\u7d22\u4e3a\u5e72\u7ec6\u80de\u6cbb\u7597\u72fc\u75ae\u6027\u80be\u708e\u79ef\u7d2f\u4e86\u5b9d\u8d35\u7ecf\u9a8c\uff0c\u4e5f\u4e3a\u672a\u6765\u7684\u4e2a\u4f53\u5316\u3001\u7cbe\u51c6\u5316\u6cbb\u7597\u5960\u5b9a\u4e86\u57fa\u7840\u3002\u53ef\u4ee5\u9884\u89c1\uff0c\u968f\u7740\u7597\u6cd5\u4f18\u5316\u4e0e\u673a\u5236\u7814\u7a76\u6df1\u5165\uff0c\u5e72\u7ec6\u80de\u7597\u6cd5\u5c06\u5728\u72fc\u75ae\u6027\u80be\u708e\u7efc\u5408\u6cbb\u7597\u4e2d\u53d1\u6325\u8d8a\u6765\u8d8a\u91cd\u8981\u7684\u4f5c\u7528\u3002<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"has-small-font-size\">References:<\/p>\n<p class=\"has-small-font-size\">[1]https:\/\/investors.centurytx.com\/news-releases\/news-release-details\/century-therapeutics-announces-investigator-initiated-phase-12<\/p>\n<p class=\"has-small-font-size\">[2]Li, J., Wu, M. &amp; He, L. Immunomodulatory effects of mesenchymal stem cell therapy in chronic kidney disease: a literature review.\u00a0<em>BMC Nephrol<\/em>\u00a0<strong>26<\/strong>, 107 (2025). https:\/\/doi.org\/10.1186\/s12882-025-04029-y<\/p>\n<p class=\"has-small-font-size\">[3]Jiang X, Jia Z, Yang B, Tang X, Feng X, Sun L. Metabolomic analysis suggests thiamine monophosphate as a potential marker for mesenchymal stem cell transplantation outcomes in patients with SLE. Lupus Science &amp; Medicine. 2025;12:e001197. https:\/\/doi.org\/10.1136\/lupus-2024-001197<\/p>\n<p class=\"has-small-font-size\">[4]Xia Y, Zhang Y, Ji J, Feng G, Chen T, Li H, Zhou F, Bao Y, Zeng X, Gu Z. Urine-derived stem cells from patients alleviate lupus nephritis via regulating macrophage polarization in a CXCL14-dependent manner. Life Sci. 2025 Jul 1;372:123623. doi: 10.1016\/j.lfs.2025.123623. Epub 2025 Apr 9. PMID: 40204070.<\/p>\n<p class=\"has-small-font-size\">[5]Liu L, Behera TR, Wang QJ, Shen QQ.\u00a0Advances in mesenchymal stem cell therapy for lupus nephritis.\u00a0<em>World J Stem Cells<\/em>\u00a02025;\u00a017(8): 104930 [PMID: 40951714 DOI: 10.4252\/wjsc.v17.i8.104930]<\/p>\n<p class=\"has-small-font-size\">[6]Tian, J., Wang, Z., Tang, Z.\u00a0<em>et al.<\/em>\u00a0Engineered exosomes conferred with ROS-regulation and immuno-suppression for ameliorating lupus nephritis.\u00a0<em>J Nanobiotechnol<\/em>\u00a0<strong>23<\/strong>, 639 (2025). https:\/\/doi.org\/10.1186\/s12951-025-03731-1<\/p>\n<p class=\"has-small-font-size\">[7]Persistent Renal Activity Despite Systemic Remission After Hematopoietic Stem Cell Transplantation in Lupus NephritisCapon, Irene Martin et al.Kidney International Reports, Volume 10, Issue 11, 4077 \u2013 4080<\/p>\n<p class=\"has-small-font-size\">Disclaimer: This article is intended only to disseminate scientific knowledge and share industry perspectives, and does not constitute any clinical diagnostic advice! The information published by Hangi Stem Cells is not a substitute for the professional advice of a physician or pharmacist. If you have any questions about copyright or other issues, please feel free to contact me.<\/p>\n<\/blockquote>","protected":false},"excerpt":{"rendered":"<p>[db:\u63cf\u8ff0]<\/p>","protected":false},"author":2,"featured_media":21356,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":{"footnotes":""},"categories":[76],"tags":[269],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21364"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/comments?post=21364"}],"version-history":[{"count":0,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21364\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media\/21356"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media?parent=21364"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/categories?post=21364"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/tags?post=21364"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}