{"id":21899,"date":"2026-04-15T18:09:37","date_gmt":"2026-04-15T10:09:37","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=21899"},"modified":"2026-04-15T18:10:22","modified_gmt":"2026-04-15T10:10:22","slug":"https-www-hjtdsm-cn-stem-cells-stem-cell-therapy-21899-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21899.html","title":{"rendered":"\u4e0d\u53ea\u662f\u201c\u6362\u7ec6\u80de\u201d\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u5982\u4f55\u901a\u8fc7\u201c\u8c03\u73af\u5883\u201d\u9006\u8f6c\u56f0\u5c40\uff1f"},"content":{"rendered":"<blockquote><p><strong>Meta\u63cf\u8ff0<\/strong>\uff1a2026\u5e74\u300a\u7ec6\u80de\u4e0e\u7ec4\u7ec7\u751f\u7269\u5b66\u300b\u7efc\u8ff0\u7cfb\u7edf\u68b3\u7406\u5e72\u7ec6\u80de\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff08\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3001\u5e15\u91d1\u68ee\u75c5\u3001ALS\u7b49\uff09\u7684\u6700\u65b0\u8bc1\u636e\u3002\u9759\u8109\u6ce8\u5c04\u3001\u9f3b\u8154\u7ed9\u836fMSCs\u53ca\u5916\u6ccc\u4f53\u5c55\u73b0\u6f5c\u529b\uff0claromestrocel\u4f7fAD\u60a3\u8005\u8111\u840e\u7f29\u51cf\u7f13\u8fd150%\uff0ciPSC\u6765\u6e90\u591a\u5df4\u80fa\u80fd\u7956\u7ec6\u80de\u83b7FDA\u518d\u751f\u533b\u5b66\u5148\u8fdb\u7597\u6cd5\u8ba4\u5b9a\u3002\u89e3\u6790\u673a\u5236\u3001\u4e34\u5e8a\u8bd5\u9a8c\u4e0e\u672a\u6765\u65b9\u5411\u3002<\/p><\/blockquote>\n<p>2026\u5e743\u670827\u65e5\uff0c\u300a\u7ec6\u80de\u4e0e\u7ec4\u7ec7\u751f\u7269\u5b66\u300b\u53d1\u8868\u7684\u4e00\u7bc7\u7814\u7a76\u7efc\u8ff0\uff0c\u7cfb\u7edf\u68b3\u7406\u4e86\u5229\u7528\u5e72\u7ec6\u80de\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u5b9e\u9a8c\u4e0e\u4e34\u5e8a\u8bc1\u636e<sup><a href=\"https:\/\/link.springer.com\/article\/10.1134\/S1990519X2603003X#citeas\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">[1]<\/a><\/sup>The<\/p>\n<p>\u6765\u81ea\u5305\u62ec\u672c\u56e2\u961f\u5728\u5185\u7684\u591a\u9879\u7814\u7a76\u8868\u660e\uff0c\u901a\u8fc7<a href=\"https:\/\/www.hjtdsm.com\/sc\/liaofa\/16944.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">\u9759\u8109\u6ce8\u5c04<\/a>\u6216\u9f3b\u8154\u7ed9\u836f\u65b9\u5f0f\u5e94\u7528<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/19927.html\/\" target=\"_blank\" rel=\"noopener\"><span class=\"xintheme_tag_link\">mesenchymal stem cell MSC (in cell biology)<\/span><\/a>\uff08MSCs\uff09\u53ca\u5176\u5206\u6ccc\u6027\u5916\u6ccc\u4f53\uff08sEVs\uff09\uff0c\u5728\u8be5\u9886\u57df\u5c55\u73b0\u51fa\u660e\u786e\u7684\u5e94\u7528\u6f5c\u529b\u3002\u8fd1\u671f\u9488\u5bf9\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7b49\u591a\u79cd\u91cd\u5927\u75be\u75c5\u5f00\u5c55\u7684\u5927\u89c4\u6a21\u5e72\u7ec6\u80de\u4e34\u5e8a\u7814\u7a76\uff0c\u4ea6\u8fdb\u4e00\u6b65\u5370\u8bc1\u4e86\u7ec6\u80de\u7597\u6cd5\u7684\u5e7f\u9614\u524d\u666f\u3002<\/p>\n<div id=\"attachment_59501\" style=\"width: 707px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-59501\" class=\"wp-image-59501\" title=\"\u4e0d\u53ea\u662f\u201c\u6362\u7ec6\u80de\u201d\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u5982\u4f55\u901a\u8fc7\u201c\u8c03\u73af\u5883\u201d\u9006\u8f6c\u56f0\u5c40\uff1f\" 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>08\u3001\u673a\u5236\u8ba4\u77e5\u5728\u53d8\uff1a\u8d77\u6548\u7684\u4e0d\u662f\u5b58\u6d3b\uff0c\u800c\u662f\u51cb\u4ea1<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21899.html\/#%E5%9B%9B%E3%80%81%E5%A4%96%E6%B3%8C%E4%BD%93%EF%BC%88sEVs%EF%BC%89%EF%BC%9A%E6%97%A0%E7%BB%86%E8%83%9E%E7%96%97%E6%B3%95%E7%9A%84%E8%BD%BD%E4%BD%93\" >\u56db\u3001\u5916\u6ccc\u4f53\uff08sEVs\uff09\uff1a\u65e0\u7ec6\u80de\u7597\u6cd5\u7684\u8f7d\u4f53<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21899.html\/#09%E3%80%81%E7%BB%99%E8%8D%AF%E9%80%94%E5%BE%84%E4%B8%8E%E5%BA%94%E7%94%A8%E5%89%8D%E6%99%AF\" >09\u3001\u7ed9\u836f\u9014\u5f84\u4e0e\u5e94\u7528\u524d\u666f<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21899.html\/#%E4%BA%94%E3%80%81%E7%BB%86%E8%83%9E%E2%80%9C%E6%89%8B%E6%9C%AF%E6%A4%8D%E5%85%A5%E2%80%9D%E4%B8%8E%E7%B1%BB%E5%99%A8%E5%AE%98%E7%96%97%E6%B3%95%EF%BC%9A%E7%BB%93%E6%9E%84%E9%87%8D%E5%BB%BA%E4%B8%8E%E5%8A%9F%E8%83%BD%E6%95%B4%E5%90%88\" >\u4e94\u3001\u7ec6\u80de\u201c\u624b\u672f\u690d\u5165\u201d\u4e0e\u7c7b\u5668\u5b98\u7597\u6cd5\uff1a\u7ed3\u6784\u91cd\u5efa\u4e0e\u529f\u80fd\u6574\u5408<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21899.html\/#010%E3%80%81%E6%89%8B%E6%9C%AF%E6%A4%8D%E5%85%A5%E7%BB%86%E8%83%9E%E7%9A%84%E4%B8%B4%E5%BA%8A%E6%8E%A2%E7%B4%A2\" >010\u3001\u624b\u672f\u690d\u5165\u7ec6\u80de\u7684\u4e34\u5e8a\u63a2\u7d22<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21899.html\/#011%E3%80%81%E7%B1%BB%E5%99%A8%E5%AE%98%E7%96%97%E6%B3%95%E7%9A%84%E7%8B%AC%E7%89%B9%E4%BC%98%E5%8A%BF\" >011\u3001\u7c7b\u5668\u5b98\u7597\u6cd5\u7684\u72ec\u7279\u4f18\u52bf<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21899.html\/#012%E3%80%81%E4%B8%B4%E5%BA%8A%E8%BD%AC%E5%8C%96%E7%8E%B0%E7%8A%B6%E4%B8%8E%E5%89%8D%E6%99%AF%E5%B1%95%E6%9C%9B\" >012\u3001\u4e34\u5e8a\u8f6c\u5316\u73b0\u72b6\u4e0e\u524d\u666f\u5c55\u671b<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21899.html\/#%E5%85%AD%E3%80%81MSCs%E4%B8%8EsEVs%E7%9A%84%E7%A5%9E%E7%BB%8F%E4%BF%9D%E6%8A%A4%E6%9C%BA%E5%88%B6%EF%BC%9A%E7%9C%9F%E6%AD%A3%E8%B5%B7%E6%95%88%E7%9A%84%E6%98%AF%E2%80%9C%E8%B0%83%E6%8E%A7%E2%80%9D\" >\u516d\u3001MSCs\u4e0esEVs\u7684\u795e\u7ecf\u4fdd\u62a4\u673a\u5236\uff1a\u771f\u6b63\u8d77\u6548\u7684\u662f\u201c\u8c03\u63a7\u201d<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21899.html\/#%E4%B8%83%E3%80%81%E7%BB%93%E8%AE%BA\" >\u4e03\u3001\u7ed3\u8bba<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21899.html\/#%E5%B8%B8%E8%A7%81%E9%97%AE%E9%A2%98%E8%A7%A3%E7%AD%94%EF%BC%88FAQ%EF%BC%89\" >\u5e38\u89c1\u95ee\u9898\u89e3\u7b54\uff08FAQ\uff09<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2 id=\"ftoc-heading-1\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%8D%E5%8F%AA%E6%98%AF%E2%80%9C%E6%8D%A2%E7%BB%86%E8%83%9E%E2%80%9D%EF%BC%9A%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%A5%9E%E7%BB%8F%E9%80%80%E8%A1%8C%E6%80%A7%E7%96%BE%E7%97%85%E5%A6%82%E4%BD%95%E9%80%9A%E8%BF%87%E2%80%9C%E8%B0%83%E7%8E%AF%E5%A2%83%E2%80%9D%E9%80%86%E8%BD%AC%E5%9B%B0%E5%B1%80%EF%BC%9F\"><\/span><strong>\u4e0d\u53ea\u662f\u201c\u6362\u7ec6\u80de\u201d\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u5982\u4f55\u901a\u8fc7\u201c\u8c03\u73af\u5883\u201d\u9006\u8f6c\u56f0\u5c40\uff1f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3 id=\"ftoc-heading-2\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%80%E3%80%81%E7%A5%9E%E7%BB%8F%E9%80%80%E8%A1%8C%E6%80%A7%E7%96%BE%E7%97%85%E4%B8%8E%E5%86%8D%E7%94%9F%E5%8C%BB%E5%AD%A6%E7%9A%84%E5%85%B3%E7%B3%BB\"><\/span><strong>\u4e00\u3001\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u4e0e\u518d\u751f\u533b\u5b66\u7684\u5173\u7cfb<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"01%E3%80%81%E4%B8%BA%E4%BB%80%E4%B9%88%E9%9C%80%E8%A6%81%E5%86%8D%E7%94%9F%E5%8C%BB%E5%AD%A6%EF%BC%9A%E7%96%BE%E7%97%85%E8%B4%9F%E6%8B%85%E5%9C%A8%E5%8A%A0%E9%87%8D%EF%BC%8C%E7%8E%B0%E6%9C%89%E7%96%97%E6%B3%95%E4%B8%8D%E5%A4%9F%E7%94%A8\"><\/span><strong>01\u3001\u4e3a\u4ec0\u4e48\u9700\u8981\u518d\u751f\u533b\u5b66\uff1a\u75be\u75c5\u8d1f\u62c5\u5728\u52a0\u91cd\uff0c\u73b0\u6709\u7597\u6cd5\u4e0d\u591f\u7528<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p><a href=\"https:\/\/www.hjtdsm.com\/sc\/shenjing\/48522.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">neurodegenerative disease<\/a>\uff08\u5982<a href=\"https:\/\/www.hjtdsm.com\/sc\/liaofa\/32897.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">senile dementia<\/a>,<a href=\"https:\/\/www.hjtdsm.com\/sc\/zhiliao\/58348.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Parkinson's disease<\/a>\u3001\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff09\u7684\u60a3\u75c5\u7387\u6b63\u968f\u4eba\u53e3\u8001\u9f84\u5316\u6301\u7eed\u6500\u5347\uff0c\u9884\u8ba1\u52302050\u5e74\u5168\u7403\u75c5\u4f8b\u5c06\u589e\u52a0\u4e24\u500d\u3002<\/p>\n<p>\u4e0e\u6b64\u540c\u65f6\uff0c\u73b0\u6709\u836f\u7269\u53ea\u80fd\u5ef6\u7f13\u75c5\u7a0b\uff0c\u65e2\u65e0\u6cd5\u9006\u8f6c\u5df2\u7ecf\u53d1\u751f\u7684\u795e\u7ecf\u5143\u4e22\u5931\uff0c\u4e5f\u96be\u4ee5\u4ece\u6839\u6e90\u4e0a\u963b\u6b62\u75be\u75c5\u8fdb\u5c55\u3002\u4e00\u8fb9\u662f\u4e0d\u65ad\u52a0\u91cd\u7684\u75be\u75c5\u8d1f\u62c5\uff0c\u4e00\u8fb9\u662f\u7597\u6548\u6709\u9650\u7684\u6cbb\u7597\u624b\u6bb5\u2014\u2014\u8fd9\u79cd\u5c40\u9762\u4fc3\u4f7f\u7814\u7a76\u8005\u5c06\u76ee\u5149\u6295\u5411\u518d\u751f\u533b\u5b66\uff0c\u5e0c\u671b\u501f\u52a9\u4fee\u590d\u6216\u66ff\u4ee3\u53d7\u635f\u795e\u7ecf\u7ec4\u7ec7\u7684\u601d\u8def\uff0c\u6253\u7834\u4f20\u7edf\u6cbb\u7597\u7684\u74f6\u9888\u3002<\/p>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"02%E3%80%81%E5%86%8D%E7%94%9F%E5%8C%BB%E5%AD%A6%E5%A6%82%E4%BD%95%E8%B5%B7%E4%BD%9C%E7%94%A8%EF%BC%9A%E6%BF%80%E6%B4%BB%E7%A5%9E%E7%BB%8F%E5%8F%91%E7%94%9F%E3%80%81%E8%B0%83%E6%8E%A7%E7%82%8E%E7%97%87%E3%80%81%E4%BF%9D%E6%8A%A4%E7%A5%9E%E7%BB%8F%E5%85%83\"><\/span><strong>02\u3001\u518d\u751f\u533b\u5b66\u5982\u4f55\u8d77\u4f5c\u7528\uff1a\u6fc0\u6d3b\u795e\u7ecf\u53d1\u751f\u3001\u8c03\u63a7\u708e\u75c7\u3001\u4fdd\u62a4\u795e\u7ecf\u5143<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>\u518d\u751f\u533b\u5b66\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7b49\u75be\u75c5\u4e2d\u7684\u6f5c\u529b\uff0c\u4e3b\u8981\u4f53\u73b0\u5728\u4e24\u4e2a\u5c42\u9762\u3002<\/p>\n<p><strong>\u4e00\u4e2a\u662f\u6fc0\u6d3b\u5185\u6e90\u6027\u795e\u7ecf\u53d1\u751f\uff1a<\/strong>\u7814\u7a76\u8bc1\u5b9e\uff0c\u6210\u5e74\u6d77\u9a6c\u9f7f\u72b6\u56de\u5b58\u5728\u795e\u7ecf\u5e72\u7ec6\u80de\uff0c\u5176\u529f\u80fd\u968f\u5e74\u9f84\u589e\u957f\u548c\u75c5\u7406\u72b6\u6001\u800c\u4e0b\u964d\uff0c\u52a8\u7269\u5b9e\u9a8c\u8868\u660e\uff0c\u901a\u8fc7\u9002\u5f53\u5e72\u9884\u53ef\u4ee5\u6539\u5584\u8ba4\u77e5\u529f\u80fd\u3002<\/p>\n<p>\u53e6\u4e00\u4e2a\u662f\u5229\u7528\u5e72\u7ec6\u80de\uff08\u5982MSCs\uff09\u53ca\u5176\u5206\u6ccc\u4ea7\u7269\uff08\u5982sEVs\uff09\u53d1\u6325<strong>\u591a\u6548\u6027\u4f5c\u7528\uff0c\u5305\u62ec\u6297\u708e\u3001\u8c03\u8282\u80f6\u8d28\u7ec6\u80de\u6d3b\u5316\u3001\u4fdd\u62a4\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u6216\u8fd0\u52a8\u795e\u7ecf\u5143<\/strong>\u7b49\u3002<\/p>\n<p>\u8fd9\u4e9b\u7b56\u7565\u4e0d\u53ea\u662f\u8bd5\u56fe\u66ff\u4ee3\u6b7b\u4ea1\u795e\u7ecf\u5143\uff0c\u66f4\u7740\u773c\u4e8e\u8c03\u63a7\u75c5\u7406\u5fae\u73af\u5883\uff0c\u5ef6\u7f13\u6216\u963b\u6b62\u795e\u7ecf\u5143\u8fdb\u4e00\u6b65\u4e22\u5931\u3002<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div id=\"attachment_59502\" style=\"width: 1386px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-59502\" class=\"wp-image-59502\" title=\"Stem cell therapy for neurodegenerative diseases\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708392590.png\" sizes=\"auto, (max-width: 1376px) 100vw, 1376px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708392590.png 1376w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708392590-768x429.png 768w\" alt=\"\u5e72\u7ec6\u80de\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\" width=\"1376\" height=\"768\" \/><p id=\"caption-attachment-59502\" class=\"wp-caption-text\">\u56fe\u6e90\uff1aAi\u751f\u6210<\/p><\/div><figcaption class=\"wp-element-caption\">\u56fe\u6e90\uff1aAI\u751f\u6210<\/figcaption><\/figure>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"03%E3%80%81%E4%BB%8E%E6%B2%BB%E7%96%97%E8%B5%B0%E5%90%91%E9%A2%84%E9%98%B2%EF%BC%9A%E5%86%8D%E7%94%9F%E5%8C%BB%E5%AD%A6%E6%89%93%E5%BC%80%E4%BA%86%E6%96%B0%E7%9A%84%E7%AA%97%E5%8F%A3\"><\/span><strong>03\u3001\u4ece\u6cbb\u7597\u8d70\u5411\u9884\u9632\uff1a\u518d\u751f\u533b\u5b66\u6253\u5f00\u4e86\u65b0\u7684\u7a97\u53e3<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u572860\u5c81\u540e\u5f80\u5f80\u8fdb\u5165\u4e0d\u53ef\u9006\u7684\u75c5\u7406\u8fdb\u7a0b\uff0c\u800c\u5f53\u524d\u9884\u9632\u624b\u6bb5\u4e25\u91cd\u532e\u4e4f\u3002\u518d\u751f\u533b\u5b66\u6b63\u88ab\u5bc4\u671b\u4e8e\u586b\u8865\u8fd9\u4e00\u7a7a\u767d\u3002<\/p>\n<p>\u5e72\u7ec6\u80de\u53ca\u5176\u4ea7\u7269\u53ef\u901a\u8fc7\u9759\u8109\u6ce8\u5c04\u3001\u9f3b\u8154\u7ed9\u836f\u7b49\u9014\u5f84\uff0c\u5728\u4e34\u5e8a\u75c7\u72b6\u51fa\u73b0\u524d10\u523020\u5e74\u8fdb\u884c\u5e72\u9884\uff0c\u5b9e\u73b0\u4ece\u201c\u88ab\u52a8\u5ef6\u7f13\u201d\u5230\u201c\u4e3b\u52a8\u4fdd\u62a4\u201d\u7684\u7406\u5ff5\u8f6c\u53d8\u3002\u8fd9\u79cd\u8f6c\u53d8\u4f53\u73b0\u4e86\u518d\u751f\u533b\u5b66\u5728\u8be5\u9886\u57df\u7684\u6838\u5fc3\u4ef7\u503c\uff1a\u4e0d\u4ec5\u4e3a\u5df2\u75c5\u60a3\u8005\u5bfb\u627e\u4fee\u590d\u8def\u5f84\uff0c\u66f4\u81f4\u529b\u4e8e\u5728\u9ad8\u5371\u4eba\u7fa4\u4e2d\u6784\u5efa\u8d77\u795e\u7ecf\u4fdd\u62a4\u5c4f\u969c\u3002<\/p>\n<h3 id=\"ftoc-heading-3\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%BA%8C%E3%80%81%E9%97%B4%E5%85%85%E8%B4%A8%E5%B9%B2%E7%BB%86%E8%83%9E%EF%BC%9A%E4%BB%8E%E6%9B%BF%E4%BB%A3%E5%88%B0%E6%97%81%E5%88%86%E6%B3%8C%EF%BC%8C%E8%AE%A4%E7%9F%A5%E5%9C%A8%E6%9B%B4%E6%96%B0\"><\/span><strong>\u4e8c\u3001\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff1a\u4ece\u66ff\u4ee3\u5230\u65c1\u5206\u6ccc\uff0c\u8ba4\u77e5\u5728\u66f4\u65b0<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u867d\u6e90\u4e8e\u4e2d\u80da\u5c42\uff0c\u4f46\u7814\u7a76\u8868\u660e\u5176\u5177\u5907\u5206\u5316\u4e3a\u80f6\u8d28\u7ec6\u80de\u548c\u795e\u7ecf\u5143\u7684\u6f5c\u80fd\u3002\u56e0\u6b64\uff0cMSCs\u88ab\u89c6\u4e3a\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7ec6\u80de\u66ff\u4ee3\u7597\u6cd5\u548c\/\u6216\u523a\u6fc0\u7597\u6cd5\u4e2d\u6781\u5177\u524d\u666f\u7684\u7ec6\u80de\u6765\u6e90\u3002<\/p>\n<p><strong>\u6765\u6e90\u4e0e\u5e94\u7528\u73b0\u72b6\uff1a<\/strong>\u76ee\u524d\u4e34\u5e8a\u4e0aMSCs\u6cbb\u7597\u591a\u91c7\u7528\u9759\u8109\u6ce8\u5c04\u6216\u5c40\u90e8\u6ce8\u5c04\u65b9\u5f0f\uff0c\u7ec6\u80de\u6765\u6e90\u4ee5\u9aa8\u9ad3\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08BM-MSC\uff09\u6700\u4e3a\u5e38\u89c1\u3002<a href=\"https:\/\/www.hjtdsm.com\/sc\/mscs\/47823.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Mesoblast\u516c\u53f8\u751f\u4ea7\u7684\u540c\u79cd\u5f02\u4f53\u548c\u81ea\u4f53BM-MSC\u4ea7\u54c1\uff08Rionsil\u3001Rexlemestrocel-L\uff09\u5df2\u4e8e2024\u5e74\u83b7\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u5bf9\u7c7b\u56fa\u9187\u8010\u836f\u7684\u6025\u6027\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5\u60a3\u513f\u3002<\/a><\/p>\n<p>\u6b64\u5916\uff0cVericel\u516c\u53f8\u7684BM-MSC\u4ea7\u54c1Ixmyelocel-T\u4e5f\u5df2\u83b7\u6279\u7528\u4e8e\u8fdb\u884c\u6027\u5fc3\u529b\u8870\u7aed\u3002\u5f53\u524d\uff0c\u540c\u79cd\u5f02\u4f53\u4e0e\u81ea\u4f53MSCs\u6cbb\u7597\u819d\u9aa8\u5173\u8282\u708e\u3001\u809d\u786c\u5316\u3001\u7f3a\u8840\u6027\u4e2d\u98ce\u7b49\u75be\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5728\u5e7f\u6cdb\u5f00\u5c55\u3002\u9664\u9aa8\u9ad3\u5916\uff0c\u8110\u5e26\u534e\u901a\u6c0f\u80f6\u3001\u80ce\u76d8\u7ec4\u7ec7\u3001\u8102\u80aa\u7ec4\u7ec7\u7b49\u4e5f\u662fMSCs\u7684\u91cd\u8981\u6765\u6e90\uff0c\u7ed9\u836f\u9014\u5f84\u6db5\u76d6\u5c40\u90e8\u4e0e\u5168\u8eab\u7ed9\u836f\u3002<\/p>\n<h3 id=\"ftoc-heading-4\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%89%E3%80%81%E6%B2%BB%E7%96%97%E7%A5%9E%E7%BB%8F%E9%80%80%E8%A1%8C%E6%80%A7%E7%96%BE%E7%97%85%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%E8%AF%81%E6%8D%AE\"><\/span><strong>\u4e09\u3001\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8bc1\u636e<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"04%E3%80%81%E9%98%BF%E5%B0%94%E8%8C%A8%E6%B5%B7%E9%BB%98%E7%97%85%EF%BC%88AD%EF%BC%89\"><\/span><strong>04\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff08AD\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>2021\u5e74\uff0c\u97e9\u56fd\u4e00\u9879\u7814\u7a76\uff08NCT03172117\uff09\u4f7f\u7528\u534e\u901a\u6c0f\u80f6\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8f7b\u4e2d\u5ea6AD\u60a3\u8005\u3002\u7ec6\u80de\u8f93\u6ce8\u524d\uff0c\u9700\u5728\u60a3\u8005\u53f3\u4fa7\u8111\u5ba4\u690d\u5165Ommaya\u50a8\u6db2\u56ca\u3002\u6bcf\u96944\u5468\u6ce8\u5c04\u4e00\u6b21\u5f02\u4f53MSCs\u540e\uff0c\u90e8\u5206\u60a3\u8005\u51fa\u73b0\u53d1\u70ed\u3001\u5934\u75db\u3001\u6076\u5fc3\u3001\u5455\u5410\u7b49\u4e0d\u826f\u53cd\u5e94\uff0c\u8be5\u7814\u7a76\u672a\u62a5\u544a\u660e\u786e\u7597\u6548\u3002<\/p>\n<p>2025\u5e74\uff0c\u97e9\u56fd\u4e09\u661f\u533b\u7597\u4e2d\u5fc3\u5b8c\u6210\u4e86\u4e00\u9879phase IIa\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bc4\u4f30\u8111\u5ba4\u5185\u6ce8\u5c04MSCs\u8054\u5408\u5730\u585e\u7c73\u677e\u6cbb\u7597AD\u7684\u6548\u679c[2]\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59500 aligncenter\" title=\"\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u8054\u5408\u5730\u585e\u7c73\u677e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\uff1a\u4e00\u9879IIa\u671f\u8bd5\u9a8c\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708381060.png\" alt=\"\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u8054\u5408\u5730\u585e\u7c73\u677e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\uff1a\u4e00\u9879IIa\u671f\u8bd5\u9a8c\" width=\"680\" height=\"433\" \/><figcaption class=\"wp-element-caption\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u8054\u5408\u5730\u585e\u7c73\u677e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\uff1a\u4e00\u9879IIa\u671f\u8bd5\u9a8c<\/figcaption><\/figure>\n<p>\u7ed3\u679c\u663e\u793a\uff0cMSCs\u5355\u72ec\u6cbb\u7597\u867d\u672a\u5e26\u6765\u663e\u8457\u7684\u4e34\u5e8a\u83b7\u76ca\uff0c\u4f46\u60a3\u8005\u8111\u810a\u6db2\u4e2d\u7684A\u03b2\u3001\u78f7\u9178\u5316tau\u548c\u603btau\u6c34\u5e73\u8f83\u5b89\u6170\u5242\u7ec4\u6709\u6240\u4e0b\u964d\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8054\u5408\u4f7f\u7528\u5730\u585e\u7c73\u677e\u53ef\u6709\u6548\u51cf\u8f7bMSCs\u8f93\u6ce8\u540e\u5e38\u89c1\u7684\u53d1\u70ed\u3001\u5934\u75db\u7b49\u514d\u75ab\u76f8\u5173\u53cd\u5e94\u3002\u7814\u7a76\u8005\u8ba4\u4e3a\uff0cMSCs\u5bf9AD\u751f\u7269\u6807\u5fd7\u7269\u5177\u6709\u63a2\u7d22\u6027\u751f\u7269\u5b66\u6548\u5e94\uff0c\u800c\u5730\u585e\u7c73\u677e\u6216\u53ef\u6210\u4e3a\u4f18\u5316\u7ec6\u80de\u6cbb\u7597\u5b89\u5168\u6027\u7684\u8f85\u52a9\u7b56\u7565\u3002<\/p>\n<p>2025\u5e743\u6708\uff0c<a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzkwOTEzMDY0Nw==&amp;mid=2247514628&amp;idx=1&amp;sn=0b5de8d90c8f15b40c431033ba6f6fb2&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">\u53e6\u4e00\u9879\u53d1\u8868\u4e8e\u300aNature Medicine\u300b\u7684\u968f\u673a\u53cc\u76f2phase IIa\u4e34\u5e8a\u8bd5\u9a8c\uff08NCT05233280\uff09\u8bc4\u4f30\u4e86laromestrocel<\/a>\u2014\u2014\u4e00\u79cd\u9aa8\u9ad3\u6765\u6e90\u7684\u540c\u79cd\u5f02\u4f53MSCs\u2014\u2014\u6cbb\u7597\u8f7b\u5ea6AD\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u300249\u540d\u60a3\u8005\u968f\u673a\u5206\u4e3a\u56db\u7ec4\uff0c\u5206\u522b\u63a5\u53d7\u4e0d\u540c\u5242\u91cf\u7684laromestrocel\u6216\u5b89\u6170\u5242\u6cbb\u7597[3]\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59499 aligncenter\" title=\"\u4f7f\u7528laromestrocel\u7684\u540c\u79cd\u5f02\u4f53\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8f7b\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5:\u4e00\u9879\u968f\u673a\u5bf9\u7167Ila\u671f\u8bd5\u9a8c\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708380891.png\" alt=\"\u4f7f\u7528laromestrocel\u7684\u540c\u79cd\u5f02\u4f53\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8f7b\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5:\u4e00\u9879\u968f\u673a\u5bf9\u7167Ila\u671f\u8bd5\u9a8c\" width=\"767\" height=\"565\" \/><figcaption class=\"wp-element-caption\">\u4f7f\u7528laromestrocel\u7684\u540c\u79cd\u5f02\u4f53\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8f7b\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5:\u4e00\u9879\u968f\u673a\u5bf9\u7167Ila\u671f\u8bd5\u9a8c<\/figcaption><\/figure>\n<p>\u4e3b\u8981\u7ec8\u70b9\u5b89\u5168\u6027\u826f\u597d\uff0c\u672a\u53d1\u751f\u4e0e\u6cbb\u7597\u76f8\u5173\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002\u5728\u6b21\u8981\u7ec8\u70b9\u65b9\u9762\uff0c<strong>\u9ad8\u5242\u91cf\u6cbb\u7597\u7ec4\u7684\u8111\u840e\u7f29\u901f\u5ea6\u8f83\u5b89\u6170\u5242\u7ec4\u51cf\u7f13\u4e86\u8fd150%\uff08\u5168\u8111\u4f53\u79ef\u5e74\u5316\u53d8\u5316\u7387-0.33%vs-0.63%\uff09\uff0c\u5de6\u4fa7\u6d77\u9a6c\u4f53\u79ef\u7684\u840e\u7f29\u4e5f\u660e\u663e\u51cf\u6162<\/strong>\u3002\u590d\u5408AD\u8bc4\u5206\u663e\u793a\uff0c\u6cbb\u7597\u7ec4\u8f83\u5b89\u6170\u5242\u7ec4\u6709\u663e\u8457\u6539\u5584\u3002\u8fd9\u4e9b\u6570\u636e\u4e3aMSCs\u6cbb\u7597\u8f7b\u5ea6AD\u7684\u8fdb\u4e00\u6b65\u4e34\u5e8a\u5f00\u53d1\u63d0\u4f9b\u4e86\u652f\u6491\u3002<\/p>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"05%E3%80%81%E5%B8%95%E9%87%91%E6%A3%AE%E7%97%85%EF%BC%88PD%EF%BC%89\"><\/span><strong>05\u3001\u5e15\u91d1\u68ee\u75c5\uff08PD\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>2026\u5e741\u6708\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6388\u4e88iRegene Therapeutics\u516c\u53f8\u7684NouvNeu001\u2014\u2014\u4e00\u79cd\u540c\u79cd\u5f02\u4f53iPSC\u6765\u6e90\u7684\u591a\u5df4\u80fa\u80fd\u7956\u7ec6\u80de\u7597\u6cd5\u2014\u2014\u518d\u751f\u533b\u5b66\u5148\u8fdb\u7597\u6cd5\uff08RMAT\uff09\u8ba4\u5b9a[4]\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59498 aligncenter\" title=\"FDA\u6388\u4e88\u5e15\u91d1\u68ee\u75c5\u5f02\u4f53iPSC\u884d\u751f\u7ec6\u80de\u7597\u6cd5RMAT\u8d44\u683c\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708380558.png\" sizes=\"auto, (max-width: 1132px) 100vw, 1132px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708380558.png 1132w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708380558-768x307.png 768w\" alt=\"FDA\u6388\u4e88\u5e15\u91d1\u68ee\u75c5\u5f02\u4f53iPSC\u884d\u751f\u7ec6\u80de\u7597\u6cd5RMAT\u8d44\u683c\" width=\"1132\" height=\"453\" \/><figcaption class=\"wp-element-caption\">FDA\u6388\u4e88\u5e15\u91d1\u68ee\u75c5\u5f02\u4f53iPSC\u884d\u751f\u7ec6\u80de\u7597\u6cd5RMAT\u8d44\u683c<\/figcaption><\/figure>\n<p>\u8fd9\u4e00\u8ba4\u5b9a\u57fa\u4e8ephase I\u4e34\u5e8a\u8bd5\u9a8c\u7684\u79ef\u6781\u6570\u636e\uff1a\u5728\u4f4e\u5242\u91cf\u7ec4\u4e2d\uff0c<strong>\u60a3\u8005MDS-UPDRS Part III\u8fd0\u52a8\u8bc4\u5206\u5728OFF\u72b6\u6001\u4e0b\u6539\u5584\u4e8630.6\u5206\uff08\u8f83\u57fa\u7ebf\u6539\u558452.8%\uff09\uff0c\u5728ON\u72b6\u6001\u4e0b\u6539\u5584\u4e8612.9\u5206\uff08\u6539\u558454.7%\uff09\uff0c\u7597\u6548\u6301\u7eed\u81f315\u4e2a\u6708\u968f\u8bbf\u671f<\/strong>\u3002\u9ad8\u5242\u91cf\u7ec4\u4e5f\u89c2\u5bdf\u5230\u4e86\u7c7b\u4f3c\u7684\u6539\u5584\u8d8b\u52bf\u3002NouvNeu001\u6b64\u524d\u5df2\u4e8e2025\u5e748\u6708\u83b7\u5f97FDA\u5feb\u901f\u901a\u9053\u8ba4\u5b9a\u3002<\/p>\n<p>2025\u5e746\u67082\u53f7\uff0c\u65b0\u52a0\u5761\u56fd\u5bb6\u795e\u7ecf\u79d1\u5b66\u7814\u7a76\u6240\uff08NNI\uff09\u6b63\u8ba1\u5212\u542f\u52a8\u4e00\u9879\u81ea\u4f53\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u65e9\u671f\u5e15\u91d1\u68ee\u75c5\u7684phase I\u4e34\u5e8a\u8bd5\u9a8c\u3002\u8be5\u7814\u7a76\u5c06\u5229\u7528\u60a3\u8005\u81ea\u8eab\u7684\u76ae\u80a4\u6216\u8840\u7ec6\u80de\uff0c\u901a\u8fc7\u4e13\u5229\u6280\u672f\u5c06\u5176\u8f6c\u5316\u4e3a\u9ad8\u7eaf\u5ea6\u7684\u591a\u5df4\u80fa\u80fd\u795e\u7ecf\u5143\u524d\u4f53\u7ec6\u80de\uff0c\u518d\u79fb\u690d\u56de\u60a3\u8005\u8111\u5185[5]\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59497 aligncenter\" title=\"\u65b0\u52a0\u5761\u7814\u7a76\u4eba\u5458\u5c06\u5728\u4e00\u9879\u65b0\u8bd5\u9a8c\u4e2d\u7814\u7a76\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u8111\u90e8\u7597\u6cd5\u3002\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708380228.png\" sizes=\"auto, (max-width: 1368px) 100vw, 1368px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708380228.png 1368w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708380228-768x203.png 768w\" alt=\"\u65b0\u52a0\u5761\u7814\u7a76\u4eba\u5458\u5c06\u5728\u4e00\u9879\u65b0\u8bd5\u9a8c\u4e2d\u7814\u7a76\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u8111\u90e8\u7597\u6cd5\u3002\" width=\"1368\" height=\"362\" \/><figcaption class=\"wp-element-caption\">\u65b0\u52a0\u5761\u7814\u7a76\u4eba\u5458\u5c06\u5728\u4e00\u9879\u65b0\u8bd5\u9a8c\u4e2d\u7814\u7a76\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u7684\u8111\u90e8\u7597\u6cd5\u3002<\/figcaption><\/figure>\n<p>\u636e\u9879\u76ee\u8d1f\u8d23\u4eba\u4ecb\u7ecd\uff0c\u8be5\u7597\u6cd5\u6b63\u5728\u63a5\u53d7FDA\u7684\u6700\u7ec8\u5ba1\u8bc4\uff0c\u82e5\u83b7\u6279\uff0c\u6709\u671b\u4e8e2026\u5e74\u5e95\u542f\u52a8\uff0c\u9996\u6279\u7eb3\u51655-8\u540d\u60a3\u8005\u3002\u8fd9\u4e00\u7b56\u7565\u7684\u4f18\u52bf\u5728\u4e8e\u4f7f\u7528\u60a3\u8005\u81ea\u4f53\u7ec6\u80de\uff0c\u53ef\u907f\u514d\u514d\u75ab\u6392\u65a5\u53cd\u5e94\u3002<\/p>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"06%E3%80%81%E8%82%8C%E8%90%8E%E7%BC%A9%E4%BE%A7%E7%B4%A2%E7%A1%AC%E5%8C%96%E7%97%87%EF%BC%88ALS%EF%BC%89\"><\/span><strong>06\u3001\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff08ALS\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>\u4e24\u9879\u4e34\u5e8a\u7814\u7a76\u8bc4\u4f30\u4e86MSCs\u5bf9ALS\u7684\u7597\u6548\u3002<\/p>\n<p>2019\u5e74\uff0c\u6b27\u6d32\u4e00\u9879\u7814\u7a76\uff08NCT02166021\uff09\u5728\u6d3b\u52a8\u6027\u8fdb\u5c55\u578b\u591a\u53d1\u6027\u786c\u5316\u75c7\u60a3\u8005\u4e2d\u6bd4\u8f83\u4e86\u9798\u5185\u4e0e\u9759\u8109\u6ce8\u5c04MSCs\u7684\u6548\u679c\uff0c\u7ed3\u679c\u663e\u793a\u9798\u5185\u7ed9\u836f\u66f4\u5177\u4f18\u52bf\uff0c\u4e14\u672a\u53d1\u73b0\u4e25\u91cd\u5b89\u5168\u95ee\u9898[6]\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59504\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/202604070843572.png\" sizes=\"auto, (max-width: 950px) 100vw, 950px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/202604070843572.png 950w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/202604070843572-768x222.png 768w\" alt=\"\" width=\"950\" height=\"274\" title=\"\"><figcaption><\/figcaption><\/figure>\n<p>\u800c\u7f8e\u56fd\u4e00\u9879\u7814\u7a76\uff08NCT03280056\uff09\u4e2d\uff0cALS\u60a3\u8005\u63a5\u53d7\u4e09\u6b21\u81ea\u4f53BM-MSC\u8f93\u6ce8\u540e\uff0c\u672a\u80fd\u89c2\u5bdf\u5230\u795e\u7ecf\u708e\u75c7\u6216\u9000\u884c\u6027\u53d8\u7684\u663e\u8457\u51cf\u8f7b\u2014\u2014\u7814\u7a76\u8005\u8ba4\u4e3a\u8fd9\u53ef\u80fd\u4e0e\u75be\u75c5\u665a\u671f\u5927\u8111\u5df2\u53d1\u751f\u4e0d\u53ef\u9006\u635f\u4f24\u6709\u5173\u3002<\/p>\n<p>2025\u5e74\u53d1\u8868\u4e8e\u300aNeural Regeneration Research\u300b\u7684\u4e00\u7bc7\u6848\u4f8b\u62a5\u544a\uff0c\u63cf\u8ff0\u4e86\u4e00\u4f4d81\u5c81\u665a\u671fALS\u60a3\u8005\u7684\u6cbb\u7597\u7ecf\u5386\u3002\u8be5\u60a3\u8005\u901a\u8fc7FDA\u6279\u51c6\u7684\u5355\u60a3\u8005\u6269\u5927\u4f7f\u7528\u901a\u9053\uff0c\u63a5\u53d7\u4e86\u6bcf\u5468\u4e00\u6b21\u3001\u8fde\u7eed8\u6b21\u7684\u5f02\u4f53\u65bd\u4e07\u7ec6\u80de\u6765\u6e90\u5916\u6ccc\u4f53\u9759\u8109\u8f93\u6ce8[7]\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59496 aligncenter\" title=\"\u5229\u7528\u540c\u79cd\u5f02\u4f53\u96ea\u65fa\u7ec6\u80de\u6765\u6e90\u7684\u5916\u6ccc\u4f53\u56ca\u6ce1\u6cbb\u7597\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff1a\u75c5\u4f8b\u62a5\u544a\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708380035.png\" sizes=\"auto, (max-width: 920px) 100vw, 920px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708380035.png 920w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708380035-768x328.png 768w\" alt=\"\u5229\u7528\u540c\u79cd\u5f02\u4f53\u96ea\u65fa\u7ec6\u80de\u6765\u6e90\u7684\u5916\u6ccc\u4f53\u56ca\u6ce1\u6cbb\u7597\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff1a\u75c5\u4f8b\u62a5\u544a\" width=\"920\" height=\"393\" \/><figcaption class=\"wp-element-caption\">\u5229\u7528\u540c\u79cd\u5f02\u4f53\u96ea\u65fa\u7ec6\u80de\u6765\u6e90\u7684\u5916\u6ccc\u4f53\u56ca\u6ce1\u6cbb\u7597\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff1a\u75c5\u4f8b\u62a5\u544a<\/figcaption><\/figure>\n<p>\u6cbb\u7597\u671f\u95f4\u672a\u89c2\u5bdf\u5230\u4efb\u4f55\u8f93\u6ce8\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u6216\u751f\u547d\u4f53\u5f81\u5f02\u5e38\u3002\u867d\u7136\u8840\u6e05\u795e\u7ecf\u4e1d\u8f7b\u94fe\u7b49\u751f\u7269\u6807\u5fd7\u7269\u672a\u5448\u73b0\u660e\u786e\u7684\u53d8\u5316\u8d8b\u52bf\uff0c\u4f46\u60a3\u8005\u7684\u4e34\u5e8a\u529f\u80fd\u5728\u8f93\u6ce8\u671f\u5185\u8d8b\u4e8e\u7a33\u5b9a\u3002\u7814\u7a76\u8005\u8ba4\u4e3a\uff0c\u8fd9\u4e00\u65b0\u578b\u6cbb\u7597\u65b9\u6848\u7684\u5b89\u5168\u6027\u5f97\u5230\u4e86\u521d\u6b65\u9a8c\u8bc1\u3002<\/p>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"07%E3%80%81%E5%85%B6%E4%BB%96%E7%96%BE%E7%97%85%E4%B8%8E%E9%A2%84%E9%98%B2%E6%80%A7%E5%BA%94%E7%94%A8\"><\/span><strong>07\u3001\u5176\u4ed6\u75be\u75c5\u4e0e\u9884\u9632\u6027\u5e94\u7528<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>\u8d8a\u5357\u4e00\u9879\u7814\u7a76\u5c06\u81ea\u4f53\u8102\u80aa\u6765\u6e90MSCs\u9759\u8109\u6ce8\u5c04\u7ed9\u4f34\u6709\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u6c34\u5e73\u5347\u9ad8\u7684\u4ee3\u8c22\u6027\u75be\u75c5\u60a3\u8005\uff0c\u7ed3\u679c\u663e\u793aIL-1\u03b1\u3001IL-1\u03b2\u3001IL-6\u3001IL-8\u53caTNF-\u03b1\u6c34\u5e73\u4e0b\u964d\uff0c\u63d0\u793a\u8840\u6db2\u4e2d\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u6c34\u5e73\u6216\u53ef\u4f5c\u4e3a\u8bc4\u4f30MSCs\u9884\u9632\u6027\u6cbb\u7597\u6548\u679c\u7684\u6f5c\u5728\u6307\u6807\u3002\u6b64\u5916\uff0c\u591a\u9879\u52a8\u7269\u5b9e\u9a8c\u4e5f\u8bc1\u5b9e\u4e86MSCs\u7684\u79ef\u6781\u4f5c\u7528\uff0c\u4f8b\u5982\u6062\u590d\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u6a21\u578b\u5c0f\u9f20\u7684\u7a7a\u95f4\u8bb0\u5fc6\uff0c\u4ee5\u53ca\u63d0\u9ad8\u521b\u4f24\u6027\u8111\u635f\u4f24\u6a21\u578b\u5927\u9f20\u7684\u5b58\u6d3b\u7387\u5e76\u51cf\u8f7b\u795e\u7ecf\u529f\u80fd\u7f3a\u635f\u3002<\/p>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"08%E3%80%81%E6%9C%BA%E5%88%B6%E8%AE%A4%E7%9F%A5%E5%9C%A8%E5%8F%98%EF%BC%9A%E8%B5%B7%E6%95%88%E7%9A%84%E4%B8%8D%E6%98%AF%E5%AD%98%E6%B4%BB%EF%BC%8C%E8%80%8C%E6%98%AF%E5%87%8B%E4%BA%A1\"><\/span><strong>08\u3001\u673a\u5236\u8ba4\u77e5\u5728\u53d8\uff1a\u8d77\u6548\u7684\u4e0d\u662f\u5b58\u6d3b\uff0c\u800c\u662f\u51cb\u4ea1<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>\u4e00\u4e2a\u6709\u610f\u601d\u7684\u73b0\u8c61\u662f\uff1a\u5c3d\u7ba1\u9759\u8109\u6216\u5c40\u90e8\u6ce8\u5c04\u540eMSCs\u7684\u5b58\u6d3b\u7387\u5f88\u4f4e\uff0c\u5927\u91cf\u7814\u7a76\u5374\u663e\u793a\u51fa\u4e86\u79ef\u6781\u7684\u6cbb\u7597\u6548\u5e94\u3002\u73b0\u5728\u7684\u4e3b\u6d41\u89c2\u70b9\u8ba4\u4e3a\uff0cMSCs\u79fb\u690d\u540e\u7684\u7834\u574f\u8fc7\u7a0b\u672c\u8eab\uff0c\u53ef\u80fd\u6b63\u662f\u5176\u53d1\u6325\u7597\u6548\u7684\u5173\u952e\u3002MSCs\u51cb\u4ea1\u8fc7\u7a0b\u4e2d\u5f62\u6210\u7684\u51cb\u4ea1\u5c0f\u4f53\u53ca\u91ca\u653e\u7684\u8425\u517b\u56e0\u5b50\uff0c\u53ef\u88ab\u5de8\u566c\u7ec6\u80de\u5feb\u901f\u8bc6\u522b\u548c\u5185\u541e\uff0c\u4fc3\u4f7f\u5176\u5411\u6297\u708eM2\u8868\u578b\u6781\u5316\uff0c\u589e\u52a0\u6297\u708e\u56e0\u5b50\u5206\u6ccc\uff0c\u4ece\u800c\u6291\u5236\u708e\u75c7\u53cd\u5e94\u5e76\u52a0\u901f\u7ec4\u7ec7\u4fee\u590d\u3002<\/p>\n<p>\u57fa\u4e8e\u8fd9\u4e00\u673a\u5236\uff0c\u7814\u7a76\u8005\u63d0\u51fa\u4e86\u201c\u65e0\u7ec6\u80de\u7597\u6cd5\u201d\u2014\u2014\u5229\u7528MSC\u6765\u6e90\u7684\u5c0f\u7ec6\u80de\u5916\u56ca\u6ce1\uff08sEVs\uff09\u8bf1\u5bfc\u5de8\u566c\u7ec6\u80deM2\u6781\u5316\uff0c\u53d1\u6325\u514d\u75ab\u8c03\u8282\u4e0e\u7ec4\u7ec7\u4fee\u590d\u4f5c\u7528\u3002\u5f53\u524dMSCs\u7684\u5e94\u7528\u8d8b\u52bf\u4ee5\u9759\u8109\u6ce8\u5c04\u81ea\u4f53\u7ec6\u80de\u4e3a\u4e3b\uff0c\u6765\u6e90\u591a\u4e3a\u9aa8\u9ad3\u6216\u8102\u80aa\u7ec4\u7ec7\u3002<\/p>\n<h3 id=\"ftoc-heading-5\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E5%9B%9B%E3%80%81%E5%A4%96%E6%B3%8C%E4%BD%93%EF%BC%88sEVs%EF%BC%89%EF%BC%9A%E6%97%A0%E7%BB%86%E8%83%9E%E7%96%97%E6%B3%95%E7%9A%84%E8%BD%BD%E4%BD%93\"><\/span><strong>\u56db\u3001\u5916\u6ccc\u4f53\uff08sEVs\uff09\uff1a\u65e0\u7ec6\u80de\u7597\u6cd5\u7684\u8f7d\u4f53<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u4f5c\u4e3aMSCs\u7684\u66ff\u4ee3\u65b9\u6848\uff0c\u7ec6\u80de\u5916\u56ca\u6ce1\u56e0\u5176\u72ec\u7279\u4f18\u52bf\u53d7\u5230\u5e7f\u6cdb\u5173\u6ce8\u3002\u5728\u591a\u7ec6\u80de\u751f\u7269\u4e2d\uff0c\u7ec6\u80de\u95f4\u901a\u8fc7\u4ea4\u6362\u7ef4\u6301\u7a33\u6001\u6240\u5fc5\u9700\u7684\u4fe1\u606f\u8fdb\u884c\u901a\u8baf\u3002\u758f\u6c34\u6027\u5206\u5b50\u53ca\u9057\u4f20\u7269\u8d28\uff08DNA\u3001RNA\u3001mRNA\uff09\u88ab\u5305\u88c5\u8fdb\u819c\u56ca\u6ce1\u4e2d\uff0c\u8fd9\u4e9b\u5206\u6ccc\u51fa\u7684\u819c\u5305\u88f9\u56ca\u6ce1\u7edf\u79f0\u4e3a\u7ec6\u80de\u5916\u56ca\u6ce1\uff0c\u5305\u62ec\u5916\u6ccc\u4f53\u3001ectosomes\u3001\u5fae\u56ca\u6ce1\u3001\u5fae\u7c92\u3001\u51cb\u4ea1\u5c0f\u4f53\u7b49\u3002<\/p>\n<p>\u5176\u4e2d\uff0c\u76f4\u5f8430\u2013150nm\u7684\u5c0f\u7ec6\u80de\u5916\u56ca\u6ce1\uff08sEVs\uff0c\u6216\u79f0\u5916\u6ccc\u4f53\uff09\u88ab\u8ba4\u4e3a\u627f\u62c5\u7740\u7ec6\u80de\u95f4\u201c\u6570\u636e\u5305\u201d\u4fe1\u53f7\u4f20\u9012\u7684\u5173\u952e\u529f\u80fd\uff08\u56fe1\uff09\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59505 aligncenter\" title=\"\u56fe1\uff1a\u7ec6\u80de\u3001\u7ec4\u7ec7\u548c\u900f\u5c04\u7535\u955c (TEM) \u4e0b\u7684\u5c0f\u578b\u7ec6\u80de\u5916\u56ca\u6ce1 (sEVs)\u3002\u7ec6\u80de\u4ea7\u751f\u7684 sEVs\uff08\u4f8b\u5982\uff0c\u5916\u6ccc\u4f53\uff09\u76f4\u5f84\u4e3a 30\u2013150 nm\uff0c\u53ef\u4ee5\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c\u3002\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026040708462598.png\" alt=\"\u56fe1\uff1a\u7ec6\u80de\u3001\u7ec4\u7ec7\u548c\u900f\u5c04\u7535\u955c(TEM) \u4e0b\u7684\u5c0f\u578b\u7ec6\u80de\u5916\u56ca\u6ce1(sEVs)\u3002\u7ec6\u80de\u4ea7\u751f\u7684sEVs\uff08\u4f8b\u5982\uff0c\u5916\u6ccc\u4f53\uff09\u76f4\u5f84\u4e3a30\u2013150 nm\uff0c\u53ef\u4ee5\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c\u3002\" width=\"685\" height=\"227\" \/><figcaption class=\"wp-element-caption\">\u56fe1\uff1a\u7ec6\u80de\u3001\u7ec4\u7ec7\u548c\u900f\u5c04\u7535\u955c (TEM) \u4e0b\u7684\u5c0f\u578b\u7ec6\u80de\u5916\u56ca\u6ce1 (sEVs)\u3002\u7ec6\u80de\u4ea7\u751f\u7684 sEVs\uff08\u4f8b\u5982\uff0c\u5916\u6ccc\u4f53\uff09\u76f4\u5f84\u4e3a 30\u2013150 nm\uff0c\u53ef\u4ee5\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c\u3002<\/figcaption><\/figure>\n<p>\u4e0eMSCs\u76f8\u6bd4\uff0csEVs\u5177\u5907\u4f4e\u514d\u75ab\u539f\u6027\u3001\u65e0\u4f26\u7406\u4e89\u8bae\u3001\u53ef\u51b7\u51bb\u957f\u671f\u50a8\u5b58\u7b49\u4f18\u52bf\u3002\u9f3b\u8154\u7ed9\u836f\u662f\u5176\u6781\u5177\u524d\u666f\u7684\u7ed9\u836f\u65b9\u5f0f\u4e4b\u4e00\u3002\u672c\u56e2\u961f\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u5c0f\u9f20\u6a21\u578b\u4e2d\u7684\u5b9e\u9a8c\u5df2\u8bc1\u5b9esEVs\u9f3b\u5185\u7ed9\u836f\u7684\u6709\u6548\u6027\uff0c\u5e76\u9a8c\u8bc1\u4e86sEVs\u5728\u5065\u5eb7\u5c0f\u9f20\u4f53\u5185\u901a\u8fc7\u8840\u8111\u5c4f\u969c\u7684\u80fd\u529b\u3002<\/p>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"09%E3%80%81%E7%BB%99%E8%8D%AF%E9%80%94%E5%BE%84%E4%B8%8E%E5%BA%94%E7%94%A8%E5%89%8D%E6%99%AF\"><\/span><strong>09\u3001\u7ed9\u836f\u9014\u5f84\u4e0e\u5e94\u7528\u524d\u666f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>\u5229\u7528<strong>sEVs\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u65e0\u7591\u9700\u8981\u591a\u6b21\u7ed9\u836f<\/strong>\uff0c\u7ed9\u836f\u9014\u5f84\u76f4\u63a5\u5f71\u54cd\u5176\u751f\u7269\u5206\u5e03\u3001\u6cbb\u7597\u6548\u679c\u53ca\u77ed\u671f\/\u957f\u671f\u751f\u7269\u5b66\u6548\u5e94\u3002\u76ee\u524d\u4e3b\u8981\u7ed9\u836f\u9014\u5f84\u5305\u62ec\u9759\u8109\u6ce8\u5c04\u3001\u9f3b\u5185\u7ed9\u836f\u3001\u53e3\u670d\uff0c\u4ee5\u53ca\u8f83\u5c11\u4f7f\u7528\u7684\u7acb\u4f53\u5b9a\u5411\u6ce8\u5c04\u3002\u9759\u8109\u6ce8\u5c04sEVs\u53ef\u663e\u8457\u6539\u5584APP\/PS1\u5c0f\u9f20\u7684\u5b66\u4e60\u8bb0\u5fc6\u80fd\u529b\uff0c\u51cf\u5c11\u6dc0\u7c89\u6837\u86cb\u767d\u6c89\u79ef\uff0c\u5e76\u4f7f\u8840\u6db2\u4e2d\u708e\u75c7\u7ec6\u80de\u56e0\u5b50\u6c34\u5e73\u6062\u590d\u6b63\u5e38\u3002<\/p>\n<p>\u672c\u56e2\u961f\u5229\u7528\u55c5\u7403\u5207\u9664\u672f\u540e\u51fa\u73b0\u4e25\u91cd\u7a7a\u95f4\u8bb0\u5fc6\u969c\u788d\u7684AD\u5c0f\u9f20\u6a21\u578b\uff0c\u8bc1\u5b9e\u4e86\u9f3b\u5185\u7ed9\u836fsEVs\u7684\u6548\u679c\uff0cPeng\u7b49\u4eba\u7684\u7814\u7a76\u4ea6\u5f97\u51fa\u7c7b\u4f3c\u7ed3\u8bba\u3002\u53e3\u670d\u7ed9\u836f\u867d\u4f9d\u4ece\u6027\u9ad8\uff0c\u4f46\u5728\u79d1\u5b66\u7814\u7a76\u4e2d\u5e94\u7528\u8f83\u5c11\u3002\u5f53\u524d\uff0c\u7814\u7a76\u8005\u6b63\u81f4\u529b\u4e8e\u63a8\u8fdbsEVs\u7684\u6807\u51c6\u5316\u751f\u4ea7\u3001\u9776\u5411\u8111\u90e8\u9012\u9001\u6280\u672f\u53ca\u5176\u4f5c\u7528\u673a\u5236\u7814\u7a76\u2014\u2014\u8fd9\u4e9b\u5de5\u4f5c\u5bf9\u4e8e\u5f00\u53d1\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u65b0\u7597\u6cd5\u81f3\u5173\u91cd\u8981\u3002<\/p>\n<h3 id=\"ftoc-heading-6\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%BA%94%E3%80%81%E7%BB%86%E8%83%9E%E2%80%9C%E6%89%8B%E6%9C%AF%E6%A4%8D%E5%85%A5%E2%80%9D%E4%B8%8E%E7%B1%BB%E5%99%A8%E5%AE%98%E7%96%97%E6%B3%95%EF%BC%9A%E7%BB%93%E6%9E%84%E9%87%8D%E5%BB%BA%E4%B8%8E%E5%8A%9F%E8%83%BD%E6%95%B4%E5%90%88\"><\/span><strong>\u4e94\u3001\u7ec6\u80de\u201c\u624b\u672f\u690d\u5165\u201d\u4e0e\u7c7b\u5668\u5b98\u7597\u6cd5\uff1a\u7ed3\u6784\u91cd\u5efa\u4e0e\u529f\u80fd\u6574\u5408<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"010%E3%80%81%E6%89%8B%E6%9C%AF%E6%A4%8D%E5%85%A5%E7%BB%86%E8%83%9E%E7%9A%84%E4%B8%B4%E5%BA%8A%E6%8E%A2%E7%B4%A2\"><\/span><strong>010\u3001\u624b\u672f\u690d\u5165\u7ec6\u80de\u7684\u4e34\u5e8a\u63a2\u7d22<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>\u5c06\u7ec6\u80de\u76f4\u63a5\u201c\u624b\u672f\u690d\u5165\u201d\u5927\u8111\u6216\u7279\u5b9a\u9776\u5668\u5b98\uff0c\u662f\u518d\u751f\u533b\u5b66\u7684\u91cd\u8981\u65b9\u5411\u3002\u4e00\u9879\u56fd\u9645I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08NCT03282760\uff09\u8bc1\u5b9e\uff0c\u5728\u514d\u75ab\u6291\u5236\u8f85\u52a9\u4e0b\uff0c\u5411\u8111\u5ba4\u5185\u6ce8\u5c04\u5f02\u4f53\u4eba\u80ce\u513f\u795e\u7ecf\u5e72\u7ec6\u80de\uff08ACT hNSC 03\/14b\u7ec6\u80de\u7cfb\uff09\uff0c\u53ef\u6709\u6548\u6291\u5236\u591a\u53d1\u6027\u786c\u5316\u75c7\u7684\u8fdb\u5c55\uff0c\u4e14\u672a\u51fa\u73b0\u660e\u663e\u4e25\u91cd\u5e76\u53d1\u75c7\u3002<\/p>\n<p>\u53e6\u4e00\u4e2a\u4ee3\u8868\u6027\u6848\u4f8b\u662f\u6717\u683c\u6c49\u65af\u80f0\u5c9b\u79fb\u690d\u3002\u9762\u5bf9\u4f9b\u4f53\u7ec4\u7ec7\u77ed\u7f3a\uff0c\u7814\u7a76\u8005\u63a2\u7d22\u4e86\u732a\u6e90\u6027\u80f0\u5c9b\u5f02\u79cd\u79fb\u690d\uff1b\u4e0e\u6b64\u540c\u65f6\uff0c\u4e2d\u56fd\u56e2\u961f\u6210\u529f\u5c06\u7531\u81ea\u4f53\u5316\u5b66\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u5206\u5316\u800c\u6765\u7684\u03b2\u7ec6\u80de\u4e09\u7ef4\u7c07\u690d\u51651\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u8179\u76f4\u808c\u4e0b\uff0c\u4e3a\u671f\u4e00\u5e74\u7684\u89c2\u5bdf\u663e\u793a\u7597\u6548\u663e\u8457\u3002\u8fd9\u4e9b\u7814\u7a76\u8bf4\u660e\uff0c\u201c\u624b\u672f\u690d\u5165\u201d\u7b56\u7565\u5728\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u53ca\u4ee3\u8c22\u6027\u75be\u75c5\u4e2d\u5177\u5907\u4e34\u5e8a\u8f6c\u5316\u6f5c\u529b\u3002<\/p>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"011%E3%80%81%E7%B1%BB%E5%99%A8%E5%AE%98%E7%96%97%E6%B3%95%E7%9A%84%E7%8B%AC%E7%89%B9%E4%BC%98%E5%8A%BF\"><\/span><strong>011\u3001\u7c7b\u5668\u5b98\u7597\u6cd5\u7684\u72ec\u7279\u4f18\u52bf<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>\u7c7b\u5668\u5b98\u4e3b\u8981\u6765\u6e90\u4e8e\u80da\u80ce\u5e72\u7ec6\u80de\uff08ESCs\uff09\u6216\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSCs\uff09\uff0c\u540e\u8005\u901a\u8fc7\u91cd\u7f16\u7a0b\u4f53\u7ec6\u80de\u83b7\u5f97\u591a\u80fd\u6027\uff0c\u53ef\u5728\u57f9\u517b\u4e2d\u81ea\u53d1\u5f62\u6210\u4e09\u7ef4\u7ed3\u6784\u3002\u8fd9\u7c7b\u201c\u8111\u7c7b\u5668\u5b98\u201d\u6216\u5d4c\u5408\u7c7b\u5668\u5b98\u4e0d\u4ec5\u80fd\u5728\u4f53\u5916\u957f\u671f\u7ef4\u6301\uff0c\u8fd8\u5177\u5907\u72ec\u7279\u7684\u7ec4\u7ec7\u4fee\u590d\u80fd\u529b\u3002<\/p>\n<p>\u7814\u7a76\u663e\u793a\uff0c\u5c06\u4eba\u8111\u7c7b\u5668\u5b98\u79fb\u690d\u81f3\u5c0f\u9f20\u4e2d\u98ce\u6a21\u578b\u540e\uff0c\u5176\u80fd\u591f\u5728\u6897\u6b7b\u533a\u5b58\u6d3b\uff0c\u5e76\u5411\u8fdc\u7aef\u8111\u533a\u53d1\u9001\u957f\u8ddd\u79bb\u8f74\u7a81\u6295\u5c04\uff0c\u6574\u5408\u5165\u5bbf\u4e3b\u795e\u7ecf\u56de\u8def\uff0c\u4ece\u800c\u4fee\u590d\u611f\u89c9\u8fd0\u52a8\u529f\u80fd\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5206\u6563\u7684\u7ec6\u80de\u79fb\u690d\u65e0\u6cd5\u5b9e\u73b0\u6b64\u7c7b\u4fee\u590d\u6548\u679c\u2014\u2014\u8fd9\u8bf4\u660e\u7c7b\u5668\u5b98\u7684\u9ad8\u5ea6\u81ea\u7ec4\u7ec7\u7ed3\u6784\u548c\u81ea\u6211\u66f4\u65b0\u80fd\u529b\u662f\u5176\u6210\u529f\u7684\u5173\u952e\u3002\u6b64\u5916\uff0c\u7c7b\u5668\u5b98\u8fd8\u53ef\u4e0e\u53d7\u635f\u5927\u9f20\u5927\u8111\u4ea7\u751f\u7ed3\u6784\u4e0e\u529f\u80fd\u4e0a\u7684\u4ea4\u4e92\u4f5c\u7528\uff0c\u5e76\u5bf9\u89c6\u89c9\u523a\u6fc0\u505a\u51fa\u53cd\u5e94\uff0c\u8fdb\u4e00\u6b65\u8bc1\u5b9e\u4e86\u5176\u6574\u5408\u6f5c\u80fd\u3002<\/p>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"012%E3%80%81%E4%B8%B4%E5%BA%8A%E8%BD%AC%E5%8C%96%E7%8E%B0%E7%8A%B6%E4%B8%8E%E5%89%8D%E6%99%AF%E5%B1%95%E6%9C%9B\"><\/span><strong>012\u3001\u4e34\u5e8a\u8f6c\u5316\u73b0\u72b6\u4e0e\u524d\u666f\u5c55\u671b<\/strong><span 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class=\"wp-block-separator has-alpha-channel-opacity\" \/>\n<h3 id=\"ftoc-heading-7\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E5%85%AD%E3%80%81MSCs%E4%B8%8EsEVs%E7%9A%84%E7%A5%9E%E7%BB%8F%E4%BF%9D%E6%8A%A4%E6%9C%BA%E5%88%B6%EF%BC%9A%E7%9C%9F%E6%AD%A3%E8%B5%B7%E6%95%88%E7%9A%84%E6%98%AF%E2%80%9C%E8%B0%83%E6%8E%A7%E2%80%9D\"><\/span><strong>\u516d\u3001MSCs\u4e0esEVs\u7684\u795e\u7ecf\u4fdd\u62a4\u673a\u5236\uff1a\u771f\u6b63\u8d77\u6548\u7684\u662f\u201c\u8c03\u63a7\u201d<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>MSCs\u4e0esEVs\u7684\u795e\u7ecf\u4fdd\u62a4\u673a\u5236\uff0c\u6838\u5fc3\u5728\u4e8e\u5176\u4f5c\u7528\u8303\u5f0f\u4ece\u201c\u7ec6\u80de\u66ff\u4ee3\u201d\u8f6c\u5411\u4e86\u201c\u5fae\u73af\u5883\u8c03\u63a7\u201d\u3002<\/p>\n<p>\u65e9\u671f\u89c2\u70b9\u5f88\u76f4\u89c2\uff1a<strong>MSCs\u8dd1\u5230\u75c5\u7076\u3001\u5206\u5316\u6210\u795e\u7ecf\u5143\u3001\u628a\u6b7b\u6389\u7684\u7ec6\u80de\u8865\u4e0a\u3002\u8fd9\u4e2a\u201c\u7ec6\u80de\u66ff\u4ee3\u201d\u5047\u8bf4\u542c\u8d77\u6765\u987a\u7406\u6210\u7ae0<\/strong>\uff0c\u4f46\u73b0\u5728\u7684\u8bc1\u636e\u8d8a\u6765\u8d8a\u6307\u5411\u53e6\u4e00\u79cd\u89e3\u91ca\u2014\u2014<strong>\u771f\u6b63\u8d77\u4f5c\u7528\u7684\u4e0d\u662f\u66ff\u4ee3\uff0c\u800c\u662f\u65c1\u5206\u6ccc<\/strong>\u3002MSCs\u672c\u8d28\u4e0a\u662f\u4e00\u4e2a\u6d3b\u7684\u201c\u836f\u7269\u5de5\u5382\u201d\uff0c\u6301\u7eed\u91ca\u653e\u4e00\u6574\u5957\u751f\u7269\u6d3b\u6027\u5206\u5b50\uff0c\u5305\u62ecGDNF\u3001NGF\u3001BDNF\u7b49\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff0c\u4ee5\u53ca\u591a\u79cd\u6297\u708e\u3001\u6297\u6c27\u5316\u7269\u8d28\u3002<\/p>\n<p>\u8fd9\u4e9b\u4e1c\u897f\u5728\u5c40\u90e8\u5fae\u73af\u5883\u91cc\u505a\u7684\u4e8b\u60c5\uff0c\u5176\u5b9e\u662f\u91cd\u7f16\u7a0b\u5bbf\u4e3b\u7ec6\u80de\u7684\u72b6\u6001\u3002\u4ee5\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e3a\u4f8b\uff0c\u5c0f\u80f6\u8d28\u7ec6\u80de\u957f\u671f\u5904\u4e8e\u4fc3\u708e\u72b6\u6001\uff0c\u91ca\u653eIL-1\u03b2\u3001TNF-\u03b1\u7b49\u708e\u75c7\u56e0\u5b50\uff0c\u53cd\u8fc7\u6765\u4f24\u5bb3\u795e\u7ecf\u5143\u3002MSCs\u5206\u6ccc\u7684IL-10\u3001TGF-\u03b2\u7b49\u5206\u5b50\uff0c\u5219\u80fd\u628a\u5c0f\u80f6\u8d28\u7ec6\u80de\u201c\u62e8\u201d\u5411\u4fee\u590d\u72b6\u6001\uff0c\u4fc3\u4f7f\u5176\u79ef\u6781\u541e\u566c\u548c\u6e05\u9664A\u03b2\u6591\u5757\u3002\u6587\u4e2d\u7279\u522b\u63d0\u5230\uff0c\u4eba\u8110\u5e26\u6765\u6e90\u7684MSCs\u80fd\u5206\u6cccGDF-15\uff0c\u8fd9\u4e2a\u56e0\u5b50\u5728\u514d\u75ab\u6291\u5236\u548c\u795e\u7ecf\u4fdd\u62a4\u65b9\u9762\u4f5c\u7528\u7a81\u51fa\u3002<\/p>\n<p>\u9664\u4e86\u5206\u6ccc\u53ef\u6eb6\u6027\u56e0\u5b50\uff0cMSCs\u8fd8\u6709\u66f4\u76f4\u63a5\u7684\u201c\u7269\u7406\u201d\u4ea4\u6d41\u65b9\u5f0f\u2014\u2014\u6bd4\u5982\u901a\u8fc7\u7eb3\u7c73\u7ba1\u628a\u7ebf\u7c92\u4f53\u76f4\u63a5\u8f6c\u79fb\u7ed9\u53d7\u635f\u795e\u7ecf\u5143\u3002\u5bf9\u4e8eAD\u795e\u7ecf\u5143\u6765\u8bf4\uff0c\u7ebf\u7c92\u4f53\u529f\u80fd\u969c\u788d\u662f\u4e00\u4e2a\u6838\u5fc3\u95ee\u9898\uff1a\u80fd\u91cf\u4ee3\u8c22\u51fa\u95ee\u9898\u3001\u6c27\u5316\u5e94\u6fc0\u5347\u9ad8\u3001\u51cb\u4ea1\u901a\u8def\u88ab\u6fc0\u6d3b\u3002MSCs\u63d0\u4f9b\u7684\u5065\u5eb7\u7ebf\u7c92\u4f53\u76f8\u5f53\u4e8e\u4e00\u6b21\u201c\u5668\u5b98\u66ff\u6362\u201d\uff0c\u80fd\u5728\u77ed\u65f6\u95f4\u5185\u6062\u590d\u7ec6\u80de\u7684\u80fd\u91cf\u4f9b\u5e94\u3002<\/p>\n<p>\u518d\u8bf4sEVs\u3002\u5b83\u672c\u8d28\u4e0a\u662fMSCs\u5206\u6ccc\u7684\u201c\u5c0f\u56ca\u6ce1\u201d\uff0c\u4f53\u79ef\u5c0f\u3001\u514d\u75ab\u539f\u6027\u4f4e\u3001\u80fd\u8fc7\u8840\u8111\u5c4f\u969c\uff0c\u5b89\u5168\u6027\u6bd4\u6d3b\u7ec6\u80de\u66f4\u597d\u3002\u5b83\u7684\u4f5c\u7528\u673a\u5236\u548cMSCs\u9ad8\u5ea6\u91cd\u53e0\uff0c\u4f46\u4e5f\u6709\u81ea\u5df1\u7684\u7279\u70b9\u3002<\/p>\n<p><strong>\u4e00\u4e2a\u662fA\u03b2\u6e05\u9664\uff1a<\/strong>sEVs\u643a\u5e26\u8111\u5561\u80bd\u9176\uff0c\u80fd\u76f4\u63a5\u964d\u89e3A\u03b2\uff1b\u540c\u65f6sEVs\u819c\u4e0a\u7684\u9798\u78f7\u8102\u80fd\u628aA\u03b2\u201c\u7c98\u201d\u4f4f\uff0c\u7136\u540e\u8ba9\u5c0f\u80f6\u8d28\u7ec6\u80de\u628a\u5b83\u541e\u6389\u3002\u8fd9\u4e24\u4e2a\u673a\u5236\u662f\u534f\u540c\u7684\u2014\u2014\u4e00\u4e2a\u6eb6\u89e3\u3001\u4e00\u4e2a\u9012\u9001\u3002<\/p>\n<p><strong>\u53e6\u4e00\u4e2a\u662f\u6297\u6c27\u5316\uff1a<\/strong>sEVs\u91cc\u542b\u6709\u8fc7\u6c27\u5316\u6c22\u9176\u7b49\u6297\u6c27\u5316\u9176\uff0c\u80fd\u76f4\u63a5\u6e05\u9664\u81ea\u7531\u57fa\u3002\u8fd9\u5728AD\u7684\u75c5\u7406\u80cc\u666f\u4e0b\u5f88\u91cd\u8981\uff0c\u56e0\u4e3aA\u03b2\u548c\u6c27\u5316\u5e94\u6fc0\u4e4b\u95f4\u672c\u6765\u5c31\u662f\u4e00\u4e2a\u6076\u6027\u5faa\u73af\u3002<\/p>\n<p>\u8fd8\u6709\u4e00\u4e2a\u7ec6\u8282\u503c\u5f97\u6ce8\u610f\uff1asEVs\u7684\u86cb\u767d\u8d28\u7ec4\u6210\u91cc\uff0c\u5927\u7ea610%\u662f\u7ebf\u7c92\u4f53\u6765\u6e90\u7684\u3002\u867d\u7136sEVs\u80fd\u4e0d\u80fd\u50cfMSCs\u90a3\u6837\u8f6c\u79fb\u5b8c\u6574\u7ebf\u7c92\u4f53\u8fd8\u6709\u4e89\u8bae\uff0c\u4f46\u81f3\u5c11\u8bf4\u660e\u5b83\u4eec\u53ef\u80fd\u53c2\u4e0e\u80fd\u91cf\u4ee3\u8c22\u7684\u8c03\u63a7\u3002<\/p>\n<p>\u6700\u540e\uff0cMSCs\u548csEVs\u7684\u4e00\u4e2a\u6838\u5fc3\u533a\u522b\u5728\u4e8e\uff1a<strong>MSCs\u662f\u6d3b\u7684\u3001\u6709\u53cd\u9988\u7684\u7cfb\u7edf\uff0c\u53ef\u4ee5\u6839\u636e\u73af\u5883\u52a8\u6001\u8c03\u6574\u5206\u6ccc\uff1b\u800csEVs\u662f\u56fa\u5b9a\u7684\u4fe1\u53f7\u5305\uff0c\u5185\u5bb9\u7269\u5728\u5206\u79bb\u65f6\u5c31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id=\"ftoc-heading-8\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%83%E3%80%81%E7%BB%93%E8%AE%BA\"><\/span><strong>\u4e03\u3001\u7ed3\u8bba<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u5728\u518d\u751f\u533b\u5b66\u9886\u57df\u5c55\u73b0\u51fa\u5de8\u5927\u6f5c\u529b\uff0c\u662f\u6781\u5177\u524d\u666f\u7684\u6cbb\u7597\u65b9\u5411\u3002\u76ee\u524d\uff0c\u5305\u62ec\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5728\u5185\u7684\u76d1\u7ba1\u673a\u6784\u5df2\u6279\u51c6\u591a\u79cd\u5f02\u4f53MSCs\u884d\u751f\u4ea7\u54c1\u7528\u4e8e\u7279\u5b9a\u9002\u5e94\u75c7\u7684\u4e34\u5e8a\u6cbb\u7597\u3002\u5927\u91cf\u6b63\u5728\u8fdb\u884c\u7684\u4e34\u5e8a\u7814\u7a76\u6b63\u81f4\u529b\u4e8e\u63a2\u7d22MSCs\u6cbb\u7597\u591a\u79cd\u75be\u75c5\uff08\u5305\u62ec\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff09\u7684\u53ef\u80fd\u6027\u3002<\/p>\n<p>\u76ee\u524d\uff0csEVs\u7684\u5e94\u7528\u7814\u7a76\u5c1a\u5904\u4e8e\u4e34\u5e8a\u524d\u9636\u6bb5\uff0c\u4e3b\u8981\u53d7\u9650\u4e8e\u5176\u751f\u4ea7\u5de5\u827a\u7684\u6807\u51c6\u5316\u95ee\u9898\u3002\u4f46sEVs\u5177\u5907\u4f53\u79ef\u5c0f\u3001\u65e0\u514d\u75ab\u539f\u6027\u3001\u8868\u9762\u5b58\u5728\u9ecf\u9644\u5206\u5b50\u3001\u80fd\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c\u7b49\u663e\u8457\u4f18\u52bf\uff0c\u5e76\u53ef\u8d1f\u8f7d\u4fc3\u667a\u836f\u7269\uff0c\u4ece\u800c\u63d0\u9ad8\u4fc3\u667a\u7597\u6cd5\u7684\u7597\u6548\u3002\u5916\u79d1\u79fb\u690d\u6e90\u81ea\u4fee\u9970MSCs\u7684\u7c7b\u5668\u5b98\u6709\u671b\u63d0\u4f9b\u66f4\u9ad8\u6548\u7684\u6cbb\u7597\uff0c\u4f46\u5176\u590d\u6742\u6027\u548c\u9ad8\u6602\u6210\u672c\u53ef\u80fd\u9650\u5236\u5176\u5e7f\u6cdb\u5e94\u7528\u3002<\/p>\n<p>\u5305\u62ec\u672c\u56e2\u961f\u83b7\u5f97\u7684\u6570\u636e\u5728\u5185\u7684\u3001\u5173\u4e8e\u9759\u8109\u548c\u9f3b\u5185\u7ed9\u836fMSCs\u4e0esEVs\u7684\u7814\u7a76\u7ed3\u679c\uff0c\u5747\u8868\u660e\u8be5\u65b9\u6cd5\u5728\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u65b9\u9762\u5177\u6709\u5de8\u5927\u6f5c\u529b\u3002\u8fd1\u5e74\u6765\u5f00\u5c55\u7684\u5927\u89c4\u6a21\u5e72\u7ec6\u80de\u6cbb\u7597\u591a\u79cd\u75be\u75c5\uff08\u5305\u62ec\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff09\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u5df2\u5145\u5206\u8bc1\u5b9e\u4e86\u7ec6\u80de\u7597\u6cd5\u7684\u5e7f\u9614\u524d\u666f\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E5%B8%B8%E8%A7%81%E9%97%AE%E9%A2%98%E8%A7%A3%E7%AD%94%EF%BC%88FAQ%EF%BC%89\"><\/span>\u5e38\u89c1\u95ee\u9898\u89e3\u7b54\uff08FAQ\uff09<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u95ee\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u73b0\u5728\u80fd\u7528\u5417\uff1f<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54<\/strong>\uff1a\u76ee\u524d\u4ecd\u5904\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\uff0c\u5c1a\u672a\u6210\u4e3a\u6807\u51c6\u6cbb\u7597\u3002\u90e8\u5206\u4ea7\u54c1\uff08\u5982laromestrocel\u3001NouvNeu001\uff09\u5df2\u8fdb\u5165II\u671f\u4e34\u5e8a\uff0c\u6570\u636e\u79ef\u6781\u3002\u56fd\u5185\u60a3\u8005\u53ef\u901a\u8fc7\u6b63\u89c4\u533b\u9662\u4e34\u5e8a\u8bd5\u9a8c\u62db\u52df\u6e20\u9053\u53c2\u4e0e\u3002<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u95ee\uff1a\u9759\u8109\u6ce8\u5c04MSCs\u80fd\u8fdb\u5165\u5927\u8111\u5417\uff1f<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54<\/strong>\uff1aMSCs\u672c\u8eab\u7a7f\u8d8a\u8840\u8111\u5c4f\u969c\u7684\u80fd\u529b\u6709\u9650\uff0c\u4f46\u5176\u5206\u6ccc\u7684sEVs\u53ef\u4ee5\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c\u3002\u9759\u8109\u6ce8\u5c04\u540eMSCs\u4e3b\u8981\u5728\u80ba\u90e8\u88ab\u622a\u7559\uff0c\u4f46\u5176\u65c1\u5206\u6ccc\u56e0\u5b50\u548c\u5916\u6ccc\u4f53\u4ecd\u53ef\u901a\u8fc7\u8840\u6db2\u5faa\u73af\u5f71\u54cd\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u3002<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u95ee\uff1a\u5916\u6ccc\u4f53\u6cbb\u7597\u6bd4MSCs\u66f4\u597d\u5417\uff1f<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54<\/strong>\uff1a\u5404\u6709\u4f18\u52a3\u3002\u5916\u6ccc\u4f53\u5728\u5b89\u5168\u6027\uff08\u65e0\u81f4\u7624\u3001\u65e0\u6813\u585e\uff09\u3001\u6807\u51c6\u5316\u751f\u4ea7\u3001\u7ed9\u836f\u4fbf\u5229\u6027\uff08\u53ef\u9f3b\u8154\u7ed9\u836f\uff09\u65b9\u9762\u6709\u4f18\u52bf\uff1b\u4f46MSCs\u662f\u6d3b\u7684\u3001\u6709\u53cd\u9988\u7684\u7cfb\u7edf\uff0c\u80fd\u6839\u636e\u5fae\u73af\u5883\u52a8\u6001\u8c03\u6574\u5206\u6ccc\u3002\u4e24\u8005\u4e0d\u662f\u66ff\u4ee3\u5173\u7cfb\uff0c\u800c\u662f\u4e92\u8865\u3002<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u95ee\uff1a\u6cbb\u7597\u8d39\u7528\u5927\u6982\u591a\u5c11\uff1f<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54<\/strong>\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u60a3\u8005\u901a\u5e38\u514d\u8d39\u3002\u672a\u6765\u5982\u679c\u83b7\u6279\u4e0a\u5e02\uff0c\u81ea\u4f53\u7ec6\u80de\u7597\u6cd5\u6210\u672c\u8f83\u9ad8\uff08\u6570\u5341\u4e07\u81f3\u767e\u4e07\u7ea7\u522b\uff09\uff0c\u5f02\u4f53\u901a\u7528\u578b\u4ea7\u54c1\u53ef\u80fd\u76f8\u5bf9\u4fbf\u5b9c\u3002\u968f\u7740\u6280\u672f\u6210\u719f\u548c\u89c4\u6a21\u5316\u751f\u4ea7\uff0c\u4ef7\u683c\u6709\u671b\u4e0b\u964d\u3002<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u95ee\uff1a\u5982\u4f55\u53c2\u52a0\u4e34\u5e8a\u8bd5\u9a8c\uff1f<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54<\/strong>\uff1a\u53ef\u901a\u8fc7\u4e2d\u56fd\u4e34\u5e8a\u8bd5\u9a8c\u6ce8\u518c\u4e2d\u5fc3\uff08<a href=\"https:\/\/www.chictr.org.cn\/\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">www.chictr.org.cn<\/a>\uff09\u6216<a href=\"https:\/\/clinicaltrials.gov\/\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">ClinicalTrials.gov<\/a>\u641c\u7d22\u76f8\u5173\u75be\u75c5\u5173\u952e\u8bcd\uff08\u5982\u201cAlzheimer\u2019s\u00a0disease mesenchymal stem cells\u201d\uff09\uff0c\u7b5b\u9009\u62db\u52df\u4e2d\u7684\u9879\u76ee\uff0c\u8054\u7cfb\u7814\u7a76\u673a\u6784\u3002<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>References:<\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[1]\uff1aPoltavtseva, RA, Svirshchevskaya, EV, Tchikov, VM\u00a0<\/span><\/span><em><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7b49\u3002<\/span><\/span><\/em><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u00a0\u5e72\u7ec6\u80de\u5728\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u6cbb\u7597\u4e2d\u7684\u5e94\u7528\u3002\u00a0<\/span><\/span><em><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7ec6\u80de\u7ec4\u7ec7\u751f\u7269\u5b66\uff0c<\/span><\/span><\/em>\u00a0<strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">20\uff0c172\u2013187<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> (2026)\u3002https:\/\/doi.org\/10.1134\/S1990519X2603003X<\/span><\/span><\/p>\n<p>[2]:Lee NK\u3001Jang H\u3001Choi Y\u3001Hwangbo S\u3001Lee S\u3001Lee JI\u3001Kim YJ\u3001Chin J\u3001Chang JW\u3001Seo SW\u3001Son HJ\u3001Choi SJ\u3001Na DL\u3001Kim HJ\u3002\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u8054\u5408\u5730\u585e\u7c73\u677e\u8f85\u52a9\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\uff1a\u4e00\u9879 IIa \u671f\u8bd5\u9a8c\u3002\u75f4\u5446\u795e\u7ecf\u8ba4\u77e5\u969c\u788d\u30022025;24(4):272-285\u3002<\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[3] Rash, BG, Ramdas, KN\u200b\u200b, Agafonova, N. \u7b49\u3002\u4f7f\u7528 laromestrocel \u8fdb\u884c\u5f02\u4f53\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8f7b\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff1a\u4e00\u9879\u968f\u673a\u5bf9\u7167 IIa \u671f\u8bd5\u9a8c\u3002Nat Med (2025)\u3002https:\/\/doi.org\/10.1038\/s41591-025-03559-0<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[4]:https:\/\/practicalneurology.com\/news\/fda-grants-rmat-designation-to-allogeneic-ipsc-derived-cell-therapy-for-parkinson-disease\/2485408\/<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[5]:https:\/\/www.singhealth.com.sg\/news\/patient-care\/s-pore-researchers-to-study-stem-cell-transplants-in-brain-for-p<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[6]:https:\/\/clinicaltrials.gov\/study\/NCT02166021?cond=NCT02166021&amp;viewType=Table&amp;rank=1<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[7]:https:\/\/www.mendeley.com\/catalogue\/1dfdd104-4166-3587-b8ac-df45cd5cc324\/ <\/span><\/span><a target=\"_blank\" rel=\"nofollow noopener\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">#cited<\/span><\/span><\/a><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> %20by-title<\/span><\/span><\/p>\n<p>\u514d\u8d23\u8bf4\u660e\uff1a\u672c\u6587\u4ec5\u7528\u4e8e\u4f20\u64ad\u79d1\u666e\u77e5\u8bc6\uff0c\u5206\u4eab\u884c\u4e1a\u89c2\u70b9\uff0c\u4e0d\u6784\u6210\u4efb\u4f55\u4e34\u5e8a\u8bca\u65ad\u5efa\u8bae\uff01\u676d\u5409\u5e72\u7ec6\u80de\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4e0d\u80fd\u66ff\u4ee3\u533b\u751f\u6216\u836f\u5242\u5e08\u7684\u4e13\u4e1a\u5efa\u8bae\u3002\u90e8\u5206\u5185\u5bb9\u7531AI\u8f85\u52a9\u6da6\u8272\u751f\u6210\uff0c\u5e76\u7ecf\u4eba\u5de5\u5ba1\u6838\u6574\u7406\u3002<\/p><\/blockquote>","protected":false},"excerpt":{"rendered":"<p>Meta\u63cf\u8ff0\uff1a2026\u5e74\u300a\u7ec6\u80de\u4e0e\u7ec4\u7ec7\u751f\u7269\u5b66\u300b\u7efc\u8ff0\u7cfb\u7edf\u68b3\u7406\u5e72\u7ec6\u80de\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff08\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u3001\u5e15\u91d1\u68ee\u75c5\u3001AL [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[76],"tags":[197,150,169],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21899"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/comments?post=21899"}],"version-history":[{"count":1,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21899\/revisions"}],"predecessor-version":[{"id":21900,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21899\/revisions\/21900"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media?parent=21899"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/categories?post=21899"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/tags?post=21899"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}