{"id":21907,"date":"2026-04-24T18:02:57","date_gmt":"2026-04-24T10:02:57","guid":{"rendered":"https:\/\/www.hjtdsm.cn\/?p=21907"},"modified":"2026-04-24T18:04:07","modified_gmt":"2026-04-24T10:04:07","slug":"https-www-hjtdsm-cn-stem-cells-stem-cell-therapy-21907-html","status":"publish","type":"post","link":"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21907.html","title":{"rendered":"\u5e72\u7ec6\u80de\u6cbb\u7597\u8001\u5e74\u8870\u5f31\uff08148\u4f8b\uff09\uff1aII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\u5b89\u5168\u6709\u6548\uff0c\u663e\u8457\u6539\u5584\u8eab\u4f53\u673a\u80fd"},"content":{"rendered":"<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p><strong>Meta\u63cf\u8ff0\uff1a<\/strong>\u300aeBioMedicine\u300b2026\u5e74\u6700\u65b0II\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff1a\u9759\u8109\u8f93\u6ce8\u8110\u5e26<span class=\"xintheme_tag_link\">mesenchymal stem cell MSC (in cell biology)<\/span>\u6cbb\u7597\u8001\u5e74\u8870\u5f31\u7efc\u5408\u5f81\uff0c9\u4e2a\u6708\u968f\u8bbf\u663e\u793a\u663e\u8457\u6539\u5584\u6b65\u901f\u3001\u63e1\u529b\u3001\u4f53\u529b\u6d3b\u52a8\u53ca\u751f\u6d3b\u8d28\u91cf\uff0c\u672a\u51fa\u73b0\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002\u9644\u5b89\u5168\u6027\u4e0e\u7597\u6548\u6570\u636e\u3001\u60a3\u8005\u5e38\u89c1\u95ee\u9898\u89e3\u7b54\u3002<\/p><\/blockquote>\n<h2 id=\"ftoc-heading-1\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%80%81%E5%B9%B4%E8%A1%B0%E5%BC%B1%EF%BC%88148%E4%BE%8B%EF%BC%89%EF%BC%9AII%E6%9C%9F%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%E6%98%BE%E7%A4%BA%E5%AE%89%E5%85%A8%E6%9C%89%E6%95%88%EF%BC%8C%E6%98%BE%E8%91%97%E6%94%B9%E5%96%84%E8%BA%AB%E4%BD%93%E6%9C%BA%E8%83%BD\"><\/span><span class=\"xintheme_tag_link\"><a title=\"stem cell therapy\" href=\"https:\/\/www.hjtdsm.com\/tag\/sc-zhiliao\" target=\"_blank\" rel=\"noopener 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href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21907.html\/#%E9%97%AE6%EF%BC%9A%E5%92%8C%E8%BF%90%E5%8A%A8%E3%80%81%E8%90%A5%E5%85%BB%E5%B9%B2%E9%A2%84%E7%9B%B8%E6%AF%94%EF%BC%8C%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%9A%84%E4%BC%98%E5%8A%BF%E5%9C%A8%E5%93%AA%E9%87%8C%EF%BC%9F\" >\u95ee6\uff1a\u548c\u8fd0\u52a8\u3001\u8425\u517b\u5e72\u9884\u76f8\u6bd4\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4f18\u52bf\u5728\u54ea\u91cc\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-26\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21907.html\/#%E9%97%AE7%EF%BC%9A%E5%93%AA%E4%BA%9B%E8%80%81%E5%B9%B4%E4%BA%BA%E4%B8%8D%E9%80%82%E5%90%88%E5%B0%9D%E8%AF%95%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%EF%BC%9F\" >\u95ee7\uff1a\u54ea\u4e9b\u8001\u5e74\u4eba\u4e0d\u9002\u5408\u5c1d\u8bd5\u5e72\u7ec6\u80de\u6cbb\u7597\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-27\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21907.html\/#%E9%97%AE8%EF%BC%9A%E4%B8%80%E6%AC%A1%E6%B2%BB%E7%96%97%E8%83%BD%E7%AE%A1%E5%A4%9A%E4%B9%85%EF%BC%9F%E9%9C%80%E8%A6%81%E9%87%8D%E5%A4%8D%E8%BE%93%E6%B3%A8%E5%90%97%EF%BC%9F\" >\u95ee8\uff1a\u4e00\u6b21\u6cbb\u7597\u80fd\u7ba1\u591a\u4e45\uff1f\u9700\u8981\u91cd\u590d\u8f93\u6ce8\u5417\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-28\" href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/stem-cell-therapy\/21907.html\/#%E5%8D%81%E4%B8%80%E3%80%81%E6%80%BB%E7%BB%93%E4%B8%8E%E5%B1%95%E6%9C%9B\" >\u5341\u4e00\u3001\u603b\u7ed3\u4e0e\u5c55\u671b<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n\n<h3 id=\"ftoc-heading-2\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E5%BC%95%E8%A8%80%EF%BC%9A%E8%80%81%E5%B9%B4%E4%BA%BA%E8%A1%B0%E5%BC%B1%E2%80%94%E2%80%94%E8%A2%AB%E5%BF%BD%E8%A7%86%E7%9A%84%E2%80%9C%E9%9A%90%E5%BD%A2%E6%9D%80%E6%89%8B%E2%80%9D\"><\/span>\u5f15\u8a00\uff1a\u8001\u5e74\u4eba\u8870\u5f31\u2014\u2014\u88ab\u5ffd\u89c6\u7684\u201c\u9690\u5f62\u6740\u624b\u201d<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u8001\u5e74\u4eba\u8870\u5f31\u7efc\u5408\u5f81\u5df2\u6210\u4e3a\u65e5\u76ca\u4e25\u5cfb\u7684\u516c\u5171\u536b\u751f\u6311\u6218\uff0c\u76f4\u63a5\u63a8\u9ad8\u8001\u5e74\u4eba\u8106\u5f31\u6027\u53ca\u4e0d\u826f\u9884\u540e\u98ce\u9669\u3002\u8870\u5f31\u5e76\u975e\u6b63\u5e38\u8870\u8001\u7684\u5fc5\u7136\u7ed3\u679c\uff0c\u800c\u662f\u4e00\u79cd\u4ee5<strong>\u751f\u7406\u50a8\u5907\u4e0b\u964d\u3001\u591a\u7cfb\u7edf\u529f\u80fd\u5931\u8c03<\/strong>\u4e3a\u7279\u5f81\u7684\u4e34\u5e8a\u72b6\u6001\uff0c\u8868\u73b0\u4e3a\u4f53\u91cd\u4e0b\u964d\u3001\u75b2\u52b3\u3001\u63e1\u529b\u51cf\u5f31\u3001\u6b65\u901f\u51cf\u6162\u3001\u4f53\u529b\u6d3b\u52a8\u51cf\u5c11\u3002\u8870\u5f31\u8001\u5e74\u4eba\u53d1\u751f\u8dcc\u5012\u3001\u4f4f\u9662\u3001\u5931\u80fd\u751a\u81f3\u6b7b\u4ea1\u7684\u98ce\u9669\u663e\u8457\u5347\u9ad8\u3002<\/p>\n<p>\u5728\u6b64\u80cc\u666f\u4e0b\uff0c<a href=\"https:\/\/www.hjtdsm.cn\/en\/stem-cells\/mscs\/20596.html\/\" target=\"_blank\" rel=\"noopener\">\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08UC-MSC\uff09<\/a>\u7597\u6cd5\u5728\u6539\u5584\u8001\u5e74\u4eba\u751f\u7406\u673a\u80fd\u4e0e\u751f\u6d3b\u8d28\u91cf\u65b9\u9762\uff0c\u521d\u663e\u826f\u597d\u524d\u666f\u3002\u4e3a\u8fdb\u4e00\u6b65\u8bc4\u4f30\u5f02\u4f53\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u9759\u8109\u8f93\u6ce8\u6cbb\u7597\u8870\u5f31\u75c7\u7684\u5b89\u5168\u6027\u4e0e\u6709\u6548\u6027\uff0c\u4e00\u9879\u53d1\u8868\u4e8e<strong>2026\u5e744\u670824\u65e5\u300aeBioMedicine\u300b<\/strong>\uff08\u7535\u5b50\u751f\u7269\u533b\u5b66\uff09\u4e3b\u9875\u7684<strong>II\u671f\u3001\u5355\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u5f00\u653e\u6807\u7b7e\u5bf9\u7167\u8bd5\u9a8c<\/strong>\u63d0\u4f9b\u4e86\u65b0\u7684\u4e34\u5e8a\u8bc1\u636e\u3002\u8be5\u8bd5\u9a8c\u901a\u8fc7\u5bf9\u4e00\u7ec4\u8001\u5e74\u8870\u5f31\u60a3\u8005\u5f00\u5c55\u957f\u8fbe\u4e5d\u4e2a\u6708\u7684\u968f\u8bbf\uff0c\u8bc4\u4f30\u4e86\u4e24\u6b21\u9759\u8109\u8f93\u6ce8\u5f02\u4f53UC-MSC\u7684\u7597\u6548<sup><a href=\"https:\/\/www.thelancet.com\/journals\/ebiom\/article\/PIIS2352-3964(26)00150-7\/fulltext#tbl1\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">[1]<\/a><\/sup>The<\/p>\n<figure class=\"wp-block-image size-full\">\n<p><div id=\"attachment_59739\" style=\"width: 1139px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-59739\" class=\"wp-image-59739\" title=\"\u5e72\u7ec6\u80de\u6cbb\u7597\u8001\u5e74\u8870\u5f31\uff08148\u4f8b\uff09\uff1aII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\u5b89\u5168\u6709\u6548\uff0c\u663e\u8457\u6539\u5584\u8eab\u4f53\u673a\u80fd\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409092020.png\" sizes=\"auto, (max-width: 1129px) 100vw, 1129px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409092020.png 1129w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409092020-768x227.png 768w\" alt=\"\u5e72\u7ec6\u80de\u6cbb\u7597\u8001\u5e74\u8870\u5f31\uff08148\u4f8b\uff09\uff1aII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\u5b89\u5168\u6709\u6548\uff0c\u663e\u8457\u6539\u5584\u8eab\u4f53\u673a\u80fd\" width=\"1129\" height=\"334\" \/><p id=\"caption-attachment-59739\" class=\"wp-caption-text\">\u5e72\u7ec6\u80de\u6cbb\u7597\u8001\u5e74\u8870\u5f31\uff08148\u4f8b\uff09\uff1aII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\u5b89\u5168\u6709\u6548\uff0c\u663e\u8457\u6539\u5584\u8eab\u4f53\u673a\u80fd<\/p><\/div><figcaption><\/figcaption><\/figure>\n<p><strong>\u6838\u5fc3\u7ed3\u679c\u6458\u8981\uff1a<\/strong><\/p>\n<ul class=\"wp-block-list\">\n<li>\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0cUC-MSC\u6cbb\u7597<strong>\u672a\u51fa\u73b0\u4e25\u91cd\u5b89\u5168\u6027\u95ee\u9898<\/strong><\/li>\n<li>\u663e\u8457\u6539\u5584\u4e86\u591a\u9879\u8eab\u4f53\u673a\u80fd\u6307\u6807\uff1aSPPB\u8bc4\u5206\u3001\u6b65\u901f\u3001\u63e1\u529b\u3001\u4f53\u529b\u6d3b\u52a8\u6c34\u5e73\u3001\u75b2\u52b3\u7a0b\u5ea6\u3001\u819d\u5173\u8282\u75c7\u72b6\u53ca\u603b\u4f53\u5065\u5eb7\u72b6\u51b5<\/li>\n<li>\u708e\u75c7\u4e0e\u8870\u8001\u76f8\u5173\u751f\u7269\u6807\u5fd7\u7269\u51fa\u73b0\u6709\u5229\u53d8\u5316\uff08IL-6\u3001TNF-\u03b1\u4e0b\u964d\uff0cp16INK4a\u964d\u4f4e\uff09<\/li>\n<li>\u652f\u6301\u5f00\u5c55\u66f4\u5927\u89c4\u6a21\u3001\u53cc\u76f2\u3001\u591a\u4e2d\u5fc3\u7684III\u671f\u8bd5\u9a8c<\/li>\n<\/ul>\n<h3 id=\"ftoc-heading-3\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%80%E3%80%81%E4%BB%80%E4%B9%88%E6%98%AF%E8%A1%B0%E5%BC%B1%E7%BB%BC%E5%90%88%E5%BE%81%EF%BC%9F%E4%B8%BA%E4%BB%80%E4%B9%88%E5%AE%83%E5%80%BC%E5%BE%97%E5%85%B3%E6%B3%A8%EF%BC%9F\"><\/span>\u4e00\u3001\u4ec0\u4e48\u662f\u8870\u5f31\u7efc\u5408\u5f81\uff1f\u4e3a\u4ec0\u4e48\u5b83\u503c\u5f97\u5173\u6ce8\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u8870\u5f31\uff08Frailty\uff09\u662f\u8001\u5e74\u4eba\u4ece\u5065\u5eb7\u72b6\u6001\u5411\u5931\u80fd\u3001\u6b7b\u4ea1\u8fc7\u6e21\u7684\u4e2d\u95f4\u72b6\u6001\uff0c\u8868\u73b0\u4e3a<strong>\u5bf9\u5916\u90e8\u5e94\u6fc0\u6e90\uff08\u5982\u611f\u67d3\u3001\u624b\u672f\u3001\u60c5\u7eea\u6ce2\u52a8\uff09\u7684\u62b5\u5fa1\u80fd\u529b\u663e\u8457\u4e0b\u964d<\/strong>\u3002\u636e\u7edf\u8ba1\uff0c65\u5c81\u4ee5\u4e0a\u8001\u5e74\u4eba\u4e2d\u8870\u5f31\u60a3\u75c5\u7387\u7ea6\u4e3a10-15%\uff0c80\u5c81\u4ee5\u4e0a\u53ef\u9ad8\u8fbe25-50%\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59740\" title=\"\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8001\u5e74\u4eba\u8870\u5f31\uff1aII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\u5b89\u5168\u6709\u6548\uff0c\u663e\u7740\u6539\u5584\u8eab\u4f53\u673a\u80fd\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/202604240910028.png\" sizes=\"auto, (max-width: 1376px) 100vw, 1376px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/202604240910028.png 1376w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/202604240910028-768x429.png 768w\" alt=\"\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8001\u5e74\u4eba\u8870\u5f31\uff1aII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\u5b89\u5168\u6709\u6548\uff0c\u663e\u7740\u6539\u5584\u8eab\u4f53\u673a\u80fd\" width=\"1376\" height=\"768\" \/><figcaption><\/figcaption><\/figure>\n<p>\u8870\u5f31\u7684\u4e34\u5e8a\u8bca\u65ad\u5e38\u7528<strong>Fried\u8870\u5f31\u8868\u578b<\/strong>\uff0c\u5305\u62ec\u4ee5\u4e0b5\u9879\u4e2d\u7684\u81f3\u5c113\u9879\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li>\u975e\u81ea\u613f\u6027\u4f53\u91cd\u4e0b\u964d\uff08\u8fc7\u53bb1\u5e74\u4e0b\u964d&gt;4.5\u516c\u65a4\uff09<\/li>\n<li>\u81ea\u8ff0\u75b2\u52b3\u611f<\/li>\n<li>\u63e1\u529b\u4e0b\u964d\uff08\u6309\u6027\u522b\u548cBMI\u5206\u5c42\uff09<\/li>\n<li>\u6b65\u901f\u51cf\u6162<\/li>\n<li>\u4f53\u529b\u6d3b\u52a8\u6c34\u5e73\u964d\u4f4e<\/li>\n<\/ul>\n<p>\u8870\u5f31\u5e76\u975e\u4e0d\u53ef\u9006\u3002\u65e9\u671f\u8bc6\u522b\u548c\u5e72\u9884\uff08\u8425\u517b\u652f\u6301\u3001\u8fd0\u52a8\u8bad\u7ec3\u3001\u591a\u5b66\u79d1\u7ba1\u7406\uff09\u53ef\u90e8\u5206\u9006\u8f6c\u3002\u7136\u800c\uff0c\u4f20\u7edf\u5e72\u9884\u624b\u6bb5\u6548\u679c\u6709\u9650\uff0c\u8feb\u5207\u9700\u8981<strong>\u4ece\u7ec6\u80de\u5c42\u9762\u4fee\u590d\u751f\u7406\u50a8\u5907<\/strong>\u7684\u65b0\u578b\u7597\u6cd5\u2014\u2014\u8fd9\u6b63\u662f\u5e72\u7ec6\u80de\u7597\u6cd5\u8fdb\u5165\u89c6\u91ce\u7684\u539f\u56e0\u3002<\/p>\n<hr class=\"wp-block-separator has-alpha-channel-opacity\" \/>\n<h3 id=\"ftoc-heading-4\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%BA%8C%E3%80%81%E4%B8%BA%E4%BB%80%E4%B9%88%E8%A6%81%E7%A0%94%E7%A9%B6%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%80%81%E5%B9%B4%E8%A1%B0%E5%BC%B1%EF%BC%9F%E2%80%94%E2%80%94%E4%BC%A0%E7%BB%9F%E6%89%8B%E6%AE%B5%E7%9A%84%E5%B1%80%E9%99%90\"><\/span>\u4e8c\u3001\u4e3a\u4ec0\u4e48\u8981\u7814\u7a76\u5e72\u7ec6\u80de\u6cbb\u7597\u8001\u5e74\u8870\u5f31\uff1f\u2014\u2014\u4f20\u7edf\u624b\u6bb5\u7684\u5c40\u9650<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u76ee\u524d\u8870\u5f31\u7684\u4e3b\u8981\u5e72\u9884\u7b56\u7565\u5305\u62ec\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u8fd0\u52a8\u5e72\u9884<\/strong>\uff1a\u6297\u963b\u8bad\u7ec3\u3001\u6709\u6c27\u8fd0\u52a8\uff08\u6709\u6548\u4f46\u4f9d\u4ece\u6027\u4f4e\uff09<\/li>\n<li><strong>\u8425\u517b\u652f\u6301<\/strong>\uff1a\u86cb\u767d\u8d28\u8865\u5145\u3001\u7ef4\u751f\u7d20D\u3001\u9499\u5242\uff08\u4f5c\u7528\u6e29\u548c\uff09<\/li>\n<li><strong>\u836f\u7269<\/strong>\uff1a\u5c1a\u65e0\u83b7\u6279\u7684\u4e13\u95e8\u6297\u8870\u5f31\u836f\u7269<\/li>\n<li><strong>\u7efc\u5408\u8001\u5e74\u8bc4\u4f30<\/strong>\uff1a\u7ba1\u7406\u591a\u91cd\u7528\u836f\u3001\u6162\u6027\u75c5<\/li>\n<\/ul>\n<p>\u8fd9\u4e9b\u65b9\u6cd5\u53ea\u80fd\u90e8\u5206\u5ef6\u7f13\u8870\u5f31\u8fdb\u5c55\uff0c<strong>\u65e0\u6cd5\u4ece\u6839\u672c\u4e0a\u9006\u8f6c\u591a\u7cfb\u7edf\u529f\u80fd\u8870\u9000<\/strong>\u3002\u800c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u5177\u6709\u4ee5\u4e0b\u7406\u8bba\u4f18\u52bf\uff1a<\/p>\n<ol class=\"wp-block-list\" start=\"1\">\n<li><strong>anti-inflammatory effect<\/strong>\uff1a\u6291\u5236\u6162\u6027\u4f4e\u5ea6\u708e\u75c7\uff08\u201c\u708e\u6027\u8870\u8001\u201d\u7684\u6838\u5fc3\u9a71\u52a8\uff09<\/li>\n<li><strong>\u4fc3\u8fdb\u7ec4\u7ec7\u4fee\u590d<\/strong>\uff1a\u65c1\u5206\u6ccc\u6548\u5e94\u523a\u6fc0\u808c\u8089\u3001\u9aa8\u9abc\u3001\u795e\u7ecf\u518d\u751f<\/li>\n<li><strong>\u6539\u5584\u7ebf\u7c92\u4f53\u529f\u80fd<\/strong>\uff1a\u8f6c\u79fb\u5065\u5eb7\u7ebf\u7c92\u4f53\uff0c\u63d0\u5347\u7ec6\u80de\u80fd\u91cf\u4ee3\u8c22<\/li>\n<li><strong>\u8c03\u8282\u514d\u75ab<\/strong>\uff1a\u6062\u590d\u514d\u75ab\u7a33\u6001<\/li>\n<\/ol>\n<p>\u56e0\u6b64\uff0cUC-MSC\u7597\u6cd5\u88ab\u89c6\u4e3a\u4e00\u79cd<strong>\u75be\u75c5\u4fee\u9970\u7b56\u7565<\/strong>\uff0c\u800c\u975e\u5355\u7eaf\u7684\u75c7\u72b6\u7ba1\u7406\u3002<\/p>\n<h3 id=\"ftoc-heading-5\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%89%E3%80%81%E6%9C%80%E6%96%B0II%E6%9C%9F%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%EF%BC%9A%E8%AE%BE%E8%AE%A1%E3%80%81%E6%96%B9%E6%B3%95%E4%B8%8E%E5%85%A5%E7%BB%84%E4%BA%BA%E7%BE%A4\"><\/span>\u4e09\u3001\u6700\u65b0II\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff1a\u8bbe\u8ba1\u3001\u65b9\u6cd5\u4e0e\u5165\u7ec4\u4eba\u7fa4<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%AF%95%E9%AA%8C%E5%9F%BA%E6%9C%AC%E4%BF%A1%E6%81%AF\"><\/span>\u8bd5\u9a8c\u57fa\u672c\u4fe1\u606f<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<figure class=\"wp-block-table is-style-stripes\">\n<table class=\"has-fixed-layout\">\n<thead>\n<tr>\n<th>\u9879\u76ee<\/th>\n<th>\u5185\u5bb9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u53d1\u8868\u671f\u520a<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">eBioMedicine\uff082026\u5e744\u670824\u65e5\uff09<\/span><\/span><\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u8bd5\u9a8c\u9636\u6bb5<\/td>\n<td>II\u671f\uff0c\u968f\u673a\u3001\u5f00\u653e\u6807\u7b7e\u3001\u8bc4\u4f30\u8005\u76f2\u6cd5\u3001\u5e73\u884c\u7ec4\u3001\u5355\u4e2d\u5fc3<\/td>\n<\/tr>\n<tr>\n<td>\u5b9e\u65bd\u5730\u70b9<\/td>\n<td>\u8d8a\u5357\u6cb3\u5185Vinmec Times City\u56fd\u9645\u7efc\u5408\u533b\u9662<\/td>\n<\/tr>\n<tr>\n<td>\u6ce8\u518c\u53f7<\/td>\n<td><a href=\"https:\/\/clinicaltrials.gov\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e34\u5e8a\u8bd5\u9a8c.gov<\/span><\/span><\/a><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u00a0NCT04919135<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u6837\u672c\u91cf<\/td>\n<td>\u6700\u7ec8\u7eb3\u5165148\u4f8b\uff08\u6cbb\u7597\u7ec473\u4f8b\uff0c\u5bf9\u7167\u7ec474\u4f8b\uff09<\/td>\n<\/tr>\n<tr>\n<td>Duration of follow-up visits<\/td>\n<td>9\u4e2a\u6708<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%B9%B2%E9%A2%84%E6%8E%AA%E6%96%BD%E4%B8%8E%E5%AF%B9%E7%85%A7\"><\/span><strong>\u5e72\u9884\u63aa\u65bd\u4e0e\u5bf9\u7167<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>UC-MSC\u8f93\u6ce8\u7ec4\u63a5\u53d7\u9759\u8109\u8f93\u6ce8\uff0c\u5242\u91cf\u4e3a<strong>1.5\u00d710\u2076\u4e2a\u7ec6\u80de\/kg<\/strong>\u4f53\u91cd\uff0c\u7ec6\u80de\u60ac\u6d6e\u4e8e50mL\u4e73\u9178\u6797\u683c\u6c0f\u6db2\u4e2d\uff0c\u6bcf\u6b21\u8f93\u6ce8\u6301\u7eed30\u5206\u949f\uff0c\u4e24\u6b21\u8f93\u6ce8\u95f4\u9694\u4e09\u4e2a\u6708\u3002\u7ec6\u80de\u6765\u6e90\u4e8e\u5065\u5eb7\u65b0\u751f\u513f\u8110\u5e26\uff0c\u5728\u65e0\u8840\u6e05\u3001\u65e0\u52a8\u7269\u6210\u5206\u6761\u4ef6\u4e0b\u57f9\u517b\u81f3\u7b2c5\u4ee3\uff0c\u5e76\u7b26\u5408\u4e25\u683c\u8d28\u91cf\u63a7\u5236\u6807\u51c6\uff08\u7ec6\u80de\u6d3b\u529b\u226585%\u3001\u8868\u9762\u6807\u5fd7\u7269\u8868\u8fbe\u8fbe\u6807\u3001\u65e0\u83cc\u53ca\u6838\u578b\u6b63\u5e38\uff09\u3002\u8f93\u6ce8\u524d\u7ed9\u4e88\u5229\u4f10\u6c99\u73ed\uff0810mg\uff09\u548c\u4e8c\u7532\u53cc\u80cd\uff0820mg\uff09\u4ee5\u9884\u9632\u8840\u6813\u98ce\u9669\u3002<\/p>\n<p>\u5bf9\u7167\u7ec4\u672a\u63a5\u53d7UC-MSC\u8f93\u6ce8\uff0c\u4ec5\u63a5\u53d7\u4e3a\u671f9\u4e2a\u6708\u7684\u53e3\u670d\u8865\u5145\u5242\uff08HighTamine\u3001\u603b\u9499\u3001Bioflex\u548c\u950c\uff09\u3002\u4e24\u7ec4\u60a3\u8005\u5747\u63a5\u53d7\u76f8\u540c\u7684\u53e3\u670d\u8865\u5145\u5242\u6cbb\u7597\u3002<\/p>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%8F%97%E8%AF%95%E8%80%85%E7%BA%B3%E5%85%A5%E4%B8%8E%E6%8E%92%E9%99%A4%E6%A0%87%E5%87%86\"><\/span><strong>\u53d7\u8bd5\u8005\u7eb3\u5165\u4e0e\u6392\u9664\u6807\u51c6<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>\u7eb3\u5165\u6807\u51c6\u5305\u62ec\uff1a\u5e74\u9f8460-85\u5c81\u3001\u7b26\u5408\u6539\u826f\u7248Fried\u8870\u5f31\u8868\u578b\u81f3\u5c11\u4e09\u9879\u3001\u6162\u6027\u8870\u5f31\u91cf\u8868\u8bc4\u52063-6\u5206\u3002\u6392\u9664\u6807\u51c6\u6db5\u76d6\uff1a\u8ba4\u77e5\u529f\u80fd\u969c\u788d\uff08MMSE\u226420\uff09\u3001\u4e25\u91cd\u5b9e\u9a8c\u5ba4\u6307\u6807\u5f02\u5e38\u3001\u4e25\u91cd\u5408\u5e76\u75c7\u3001\u8fd1\u671f\u6076\u6027\u80bf\u7624\u53f2\u53ca\u9884\u671f\u751f\u5b58\u671f\u4e0d\u8db3\u4e00\u5e74\u7b49\u3002<\/p>\n<p>\u968f\u8bbf\u65f6\u95f4\u70b9\u4e3a\u57fa\u7ebf\u30011\u4e2a\u6708\u30013\u4e2a\u6708\u30016\u4e2a\u6708\u548c9\u4e2a\u6708\uff0c\u672a\u8ba1\u5212\u4e2d\u671f\u5206\u6790\u3002<\/p>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%BB%E8%A6%81%E7%96%97%E6%95%88%E7%BB%88%E7%82%B9\"><\/span>\u4e3b\u8981\u7597\u6548\u7ec8\u70b9<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<ul class=\"wp-block-list\">\n<li>\u57fa\u7ebf\u81f39\u4e2a\u6708\u65f6<strong>\u7b80\u6613\u4f53\u80fd\u72b6\u51b5\u91cf\u8868\uff08SPPB\uff09\u603b\u5206<\/strong>\u7684\u53d8\u5316\uff08\u6700\u5c0f\u4e34\u5e8a\u91cd\u8981\u5dee\u5f02MCID=0.5\u5206\uff09<\/li>\n<\/ul>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%AC%A1%E8%A6%81%E7%96%97%E6%95%88%E7%BB%88%E7%82%B9\"><\/span>\u6b21\u8981\u7597\u6548\u7ec8\u70b9<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<ul class=\"wp-block-list\">\n<li>\u63e1\u529b\u30014\u7c73\u6b65\u901f\u3001CHAMPS\u4f53\u529b\u6d3b\u52a8\u95ee\u5377\u3001\u591a\u7ef4\u75b2\u52b3\u91cf\u8868\uff08MFI\uff09\u3001WOMAC\u819d\u5173\u8282\u8bc4\u5206\u3001SF-36\u751f\u6d3b\u8d28\u91cf\u8bc4\u5206<\/li>\n<li>\u708e\u75c7\u7ec6\u80de\u56e0\u5b50\uff08IL-6\u3001TNF-\u03b1\u7b49\uff09\u3001\u7ec6\u80de\u8870\u8001\u6807\u5fd7\u7269p16INK4a\u3001\u7ebf\u7c92\u4f53\u547c\u5438\u529f\u80fd<\/li>\n<\/ul>\n<h3 id=\"ftoc-heading-6\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E5%9B%9B%E3%80%81%E7%BB%93%E6%9E%9C\"><\/span>Four,<strong>\u7ed3\u679c<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>\u53d7\u8bd5\u8005\u7eb3\u5165\u4e0e\u57fa\u7ebf\u7279\u5f81\uff1a<\/strong>\u8be5\u7814\u7a76\u5171\u7eb3\u5165148\u540dII\u671f\u8bd5\u9a8c\u53d7\u8bd5\u8005\uff0c\u968f\u673a\u5206\u914d\u81f3UC-MSC\u8054\u5408\u8865\u5145\u5242\u6cbb\u7597\u7ec4\uff08n=74\uff09\u4e0e\u5355\u7eaf\u8865\u5145\u5242\u5bf9\u7167\u7ec4\uff08n=74\uff09\u3002\u6cbb\u7597\u7ec4\u4e2d1\u540d\u60a3\u8005\u5728\u9996\u6b21\u8f93\u6ce8\u524d\u64a4\u56de\u77e5\u60c5\u540c\u610f\uff0c\u6545\u6700\u7ec8\u5b9e\u9645\u63a5\u53d7\u4e24\u6b21\u9759\u8109\u8f93\u6ce8UC-MSC\uff08\u95f4\u96943\u4e2a\u6708\uff09\u8005\u4e3a73\u540d\u3002\u968f\u8bbf\u671f\u95f4\uff0c\u6cbb\u7597\u7ec473\u4f8b\u4e0e\u5bf9\u7167\u7ec474\u4f8b\u5168\u90e8\u5b8c\u62101\u30013\u30016\u30019\u4e2a\u6708\u968f\u8bbf\uff0c\u65e0\u5931\u8bbf\u75c5\u4f8b\u3002\u8bd5\u9a8c\u5728\u5b8c\u6210\u5168\u90e8\u9884\u8bbe\u968f\u8bbf\u540e\u7ec8\u6b62\uff0c\u968f\u673a\u5316\u8bbe\u5b9a\u7684148\u4f8b\u6837\u672c\u91cf\u4e2d\uff0c\u9664\u6cbb\u7597\u7ec41\u4f8b\u9000\u51fa\u5916\uff0c\u5176\u4f59\u5747\u5b8c\u6210\u7814\u7a76\uff08\u56fe1\uff09\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59738 aligncenter\" title=\"\u56fe1-\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8870\u5f31II\u671f\u8bd5\u9a8cCONSORT\u6d41\u7a0b\u56fe\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409091890.jpg\" alt=\"\u56fe1-\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8870\u5f31II\u671f\u8bd5\u9a8cCONSORT\u6d41\u7a0b\u56fe\" width=\"666\" height=\"555\" \/><figcaption class=\"wp-element-caption\">\u56fe1\u8bf4\u660e\uff1aCONSORT\u6d41\u7a0b\u56fe\uff0c\u5c55\u793aII\u671f\u8bd5\u9a8c\u53d7\u8bd5\u8005\u7b5b\u9009\u3001\u968f\u673a\u5206\u7ec4\u3001\u6cbb\u7597\u53ca\u968f\u8bbf\u6d41\u7a0b\u3002<\/figcaption><\/figure>\n<p>\u4e24\u7ec4\u57fa\u7ebf\u4eba\u53e3\u5b66\u53ca\u4e34\u5e8a\u53d8\u91cf\u5747\u8861\u826f\u597d\uff08p&gt;0.05\uff09\u3002UC-MSC\u7ec4\u5e73\u5747\u5e74\u9f8468.2\u00b16.3\u5c81\uff0c\u5bf9\u7167\u7ec468.7\u00b16.1\u5c81\uff1b\u5973\u6027\u5360\u6bd4\u5206\u522b\u4e3a71.2%\u548c64.9%\u3002<\/p>\n<p>\u5728\u529f\u80fd\u3001\u8eab\u4f53\u53ca\u8ba4\u77e5\u6307\u6807\u65b9\u9762\uff0c\u4e24\u7ec4SPPB\u603b\u5206\u30014\u7c73\u6b65\u884c\u6d4b\u8bd5\u3001\u63e1\u529b\u3001\u4f53\u91cd\u3001\u4f53\u529b\u6d3b\u52a8\u3001MFI\u603b\u5206\u3001WOMAC\u603b\u5206\u3001SF-36\u3001MMSE\u8bc4\u5206\u3001FEV1\/FVC\u6bd4\u503c\u53caLVEF\u5747\u65e0\u7edf\u8ba1\u5b66\u5dee\u5f02\u3002\u6162\u6027\u75b2\u52b3\u7efc\u5408\u5f81\uff08CFS\uff09\u5206\u7ea7\u5206\u5e03\u4ea6\u7ec4\u95f4\u5747\u8861\u3002<\/p>\n<p>\u5e38\u89c1\u5408\u5e76\u75c7\u4ee5\u9ad8\u8840\u538b\u4e3a\u4e3b\uff0c\u6cbb\u7597\u7ec4\u4e0e\u5bf9\u7167\u7ec4\u60a3\u75c5\u7387\u5206\u522b\u4e3a73.7%\u548c56.5%\uff1b\u7cd6\u5c3f\u75c5\u3001\u9aa8\u5173\u8282\u708e\u7b49\u53d1\u751f\u7387\u8f83\u4f4e\uff0c\u603b\u4f53\u5408\u5e76\u75c7\u7ec4\u95f4\u5747\u8861\u3002\u708e\u75c7\u4e0e\u8870\u8001\u76f8\u5173\u751f\u7269\u6807\u5fd7\u7269\u57fa\u7ebf\u6c34\u5e73\u4ea6\u4fdd\u6301\u5e73\u8861\u3002<\/p>\n<p><strong>\u7ec6\u80de\u8d28\u91cf\u8bc4\u4f30\uff1a<\/strong>\u5171\u5236\u590720\u6279UC-MSC\uff0c\u7528\u4e8e\u652f\u630173\u4f8b\u60a3\u8005\u7684146\u6b21\u8f93\u6ce8\u3002\u6240\u6709\u6279\u6b21\u5747\u7b26\u5408\u9884\u8bbe\u653e\u884c\u6807\u51c6\u3002\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u9633\u6027\u6807\u5fd7\u7269\uff08CD73\u3001CD90\u3001CD105\uff09\u8868\u8fbe\u7387\u8d85\u8fc795%\uff0c\u9634\u6027\u6807\u5fd7\u7269\uff08CD34\u3001CD45\u3001CD19\u3001CD11b\u3001HLA-DR\uff09\u8868\u8fbe\u7387\u4f4e\u4e8e2%\u3002\u6240\u6709\u6279\u6b21\u5747\u672a\u68c0\u51fa\u7ec6\u83cc\u3001\u771f\u83cc\u548c\u652f\u539f\u4f53\u6c61\u67d3\uff0c\u4e14\u6838\u578b\u6b63\u5e38\u3002<\/p>\n<p>\u89e3\u51bb\u540e\u8d28\u91cf\u8bc4\u4f30\u663e\u793a\u7ec6\u80de\u8d28\u91cf\u6301\u7eed\u8f83\u9ad8\uff0c\u7b2c\u4e00\u6b21\u548c\u7b2c\u4e8c\u6b21\u8f93\u6ce8\u7684\u5e73\u5747\u7ec6\u80de\u6d3b\u529b\u5206\u522b\u4e3a91.8\u00b12.2%\u548c90.5\u00b11.0%\u3002\u672a\u68c0\u51fa\u5fae\u751f\u7269\u6c61\u67d3\uff0c\u5185\u6bd2\u7d20\u6c34\u5e73\u4fdd\u6301\u57285EU\/kg\/\u5c0f\u65f6\u4ee5\u4e0b\uff0c\u6240\u6709\u7ed9\u836f\u5242\u91cf\u5747\u7b26\u5408\u7814\u7a76\u65b9\u6848\u3002<\/p>\n<h3 id=\"ftoc-heading-7\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%BA%94%E3%80%81%E5%AE%89%E5%85%A8%E6%80%A7%E7%BB%93%E6%9E%9C%EF%BC%9A%E4%B8%8D%E8%89%AF%E4%BA%8B%E4%BB%B6%E4%B8%8E%E4%B8%A5%E9%87%8D%E4%B8%8D%E8%89%AF%E4%BA%8B%E4%BB%B6\"><\/span>\u4e94\u3001<strong>\u5b89\u5168\u6027\u7ed3\u679c\uff1a\u4e0d\u826f\u4e8b\u4ef6\u4e0e\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff1a<\/strong>\u6574\u4e2a\u7814\u7a76\u671f\u95f4\uff0c\u4e24\u7ec4\u5747\u672a\u62a5\u544a\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff08SAE\uff09\uff0c\u4ea6\u672a\u89c2\u5bdf\u5230\u6b7b\u4ea1\u6216\u8840\u6813\u6813\u585e\u4e8b\u4ef6\u3002<\/p>\n<p><strong>\u4e0d\u826f\u4e8b\u4ef6\uff1a<\/strong>UC-MSC\u7ec4\u81f3\u5c11\u53d1\u751f\u4e00\u6b21\u4e0d\u826f\u4e8b\u4ef6\uff08AE\uff09\u7684\u60a3\u8005\u6bd4\u4f8b\u4e3a26.0%\uff0c\u5bf9\u7167\u7ec4\u4e3a8.1%\u3002\u6240\u6709\u62a5\u544a\u7684\u4e0d\u826f\u4e8b\u4ef6\u5747\u4e3aCTCAEv5.01\u7ea7\uff0c\u672a\u53d1\u751f3\u20135\u7ea7\u4e8b\u4ef6\u3002<\/p>\n<p>UC-MSC\u7ec4\u4e2d\uff0c10\u4f8b\u60a3\u8005\u53d1\u751f\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\uff0c\u5171\u8ba112\u4f8b\u6b21\uff0c\u5305\u62ec\u5934\u75db\uff086\u4f8b\uff09\u3001\u5934\u6655\uff083\u4f8b\uff09\u548c\u80f8\u90e8\u4e0d\u9002\uff083\u4f8b\uff09\uff0c\u5176\u4e2d8\u4f8b\u53d1\u751f\u4e8e\u9996\u6b21\u8f93\u6ce8\u540e\uff0c4\u4f8b\u53d1\u751f\u4e8e\u7b2c\u4e8c\u6b21\u8f93\u6ce8\u540e\uff0c\u6240\u6709\u4e8b\u4ef6\u5747\u81ea\u884c\u7f13\u89e3\uff0c\u672a\u9057\u7559\u540e\u9057\u75c7\u3002<\/p>\n<p>\u6b64\u5916\uff0cUC-MSC\u7ec4\u67099\u4f8b\u60a3\u8005\u53d1\u751f14\u4f8b\u975e\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\uff0c\u5bf9\u7167\u7ec4\u67096\u4f8b\u60a3\u8005\u53d1\u751f7\u4f8b\u975e\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\uff0c\u4e3b\u8981\u4e3a\u611f\u67d3\u3001\u808c\u8089\u9aa8\u9abc\u95ee\u9898\u53ca\u5176\u4ed6\u5e74\u9f84\u76f8\u5173\u75be\u75c5\uff08\u88681\uff09\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59737 aligncenter\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/202604240909167.png\" sizes=\"auto, (max-width: 847px) 100vw, 847px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/202604240909167.png 847w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/202604240909167-768x396.png 768w\" alt=\"\" width=\"847\" height=\"437\" title=\"\"><figcaption><\/figcaption><\/figure>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59736 aligncenter\" title=\"\u88681\uff1a\u4e0d\u826f\u4e8b\u4ef6\u548c\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u603b\u7ed3\u3002\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409091440.png\" sizes=\"auto, (max-width: 860px) 100vw, 860px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409091440.png 860w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409091440-768x150.png 768w\" alt=\"\u88681\uff1a\u4e0d\u826f\u4e8b\u4ef6\u548c\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u603b\u7ed3\u3002\" width=\"860\" height=\"168\" \/><figcaption class=\"wp-element-caption\">\u88681\uff1a\u4e0d\u826f\u4e8b\u4ef6\u548c\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u603b\u7ed3\u3002<\/figcaption><\/figure>\n<h3 id=\"ftoc-heading-8\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E5%85%AD%E3%80%81%E4%B8%BB%E8%A6%81%E7%96%97%E6%95%88%E7%BB%93%E6%9E%9C%EF%BC%9A%E5%A4%9A%E4%B8%AA%E8%BA%AB%E4%BD%93%E6%9C%BA%E8%83%BD%E6%8C%87%E6%A0%87%E6%98%BE%E8%91%97%E6%94%B9%E5%96%84\"><\/span>\u516d\u3001\u4e3b\u8981\u7597\u6548\u7ed3\u679c\uff1a\u591a\u4e2a\u8eab\u4f53\u673a\u80fd\u6307\u6807\u663e\u8457\u6539\u5584<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%BA%AB%E4%BD%93%E5%8A%9F%E8%83%BD%E5%8F%98%E5%8C%96%EF%BC%88SPPB%E3%80%81%E6%AD%A5%E9%80%9F%E3%80%81%E6%8F%A1%E5%8A%9B%EF%BC%89\"><\/span>\u8eab\u4f53\u529f\u80fd\u53d8\u5316\uff08SPPB\u3001\u6b65\u901f\u3001\u63e1\u529b\uff09<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<ul class=\"wp-block-list\">\n<li><strong>SPPB\u603b\u5206<\/strong>\uff1aUC-MSC\u7ec4\u57283\u4e2a\u6708\u30016\u4e2a\u6708\u30019\u4e2a\u6708\u65f6\u5747\u663e\u8457\u9ad8\u4e8e\u5bf9\u7167\u7ec4\uff0c\u6700\u5c0f\u4e8c\u4e58\u5747\u503c\u5dee\uff08MD\uff09\u5206\u522b\u4e3a<strong>+1.1\u5206<\/strong>\u3001+1.1\u5206\u3001+0.8\u5206\uff0c<strong>\u8d85\u8fc7MCID 0.5\u5206<\/strong>The<\/li>\n<li><strong>4\u7c73\u6b65\u901f<\/strong>\uff1a9\u4e2a\u6708\u65f6\u7ec4\u95f4\u5dee\u5f02\u6700\u5927\uff0cUC-MSC\u7ec4\u6b65\u901f\u63d0\u9ad8<strong>0.16\u7c73\/\u79d2<\/strong>\uff08\u8d85\u8fc7\u4e34\u5e8a\u610f\u4e49\u9608\u503c\uff09\u3002<\/li>\n<li><strong>\u63e1\u529b<\/strong>\uff1aUC-MSC\u7ec4\u5728\u6240\u6709\u65f6\u95f4\u70b9\u5747\u4f18\u4e8e\u5bf9\u7167\u7ec4\uff0c\u5dee\u5f02\u8303\u56f4<strong>+2.6kg\u81f3+4.0kg<\/strong>The<\/li>\n<\/ul>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59735 aligncenter\" title=\"\u56fe2-UC-MSC\u6cbb\u7597\u8870\u5f31\u529f\u80fd\u7ed3\u5c40\u53d8\u5316\u8f68\u8ff9\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409091142.jpg\" alt=\"\u56fe2\u8bf4\u660e\uff1a\u6df7\u5408\u6548\u5e94\u6a21\u578b\u8c03\u6574\u540e\u7684\u529f\u80fd\u7ed3\u5c40\u5e73\u5747\u8f68\u8ff9\uff0c\u663e\u793aUC-MSC\u7ec4\u5728SPPB\u3001\u6b65\u901f\u3001\u63e1\u529b\u7b49\u65b9\u9762\u7684\u6301\u7eed\u6539\u5584\u3002\" width=\"656\" height=\"881\" \/><figcaption class=\"wp-element-caption\"><strong>\u56fe2\u8bf4\u660e<\/strong>\uff1a\u6df7\u5408\u6548\u5e94\u6a21\u578b\u8c03\u6574\u540e\u7684\u529f\u80fd\u7ed3\u5c40\u5e73\u5747\u8f68\u8ff9\uff0c\u663e\u793aUC-MSC\u7ec4\u5728SPPB\u3001\u6b65\u901f\u3001\u63e1\u529b\u7b49\u65b9\u9762\u7684\u6301\u7eed\u6539\u5584\u3002<\/figcaption><\/figure>\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%82%A3%E8%80%85%E6%8A%A5%E5%91%8A%E7%BB%93%E5%B1%80%EF%BC%88%E4%BD%93%E5%8A%9B%E6%B4%BB%E5%8A%A8%E3%80%81%E7%96%B2%E5%8A%B3%E3%80%81%E7%94%9F%E6%B4%BB%E8%B4%A8%E9%87%8F%EF%BC%89\"><\/span>\u60a3\u8005\u62a5\u544a\u7ed3\u5c40\uff08\u4f53\u529b\u6d3b\u52a8\u3001\u75b2\u52b3\u3001\u751f\u6d3b\u8d28\u91cf\uff09<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<ul class=\"wp-block-list\">\n<li><strong>\u4f53\u529b\u6d3b\u52a8\uff08CHAMPS\uff09<\/strong>\uff1a3\u4e2a\u6708\u65f6UC-MSC\u7ec4\u6bcf\u5468\u80fd\u91cf\u6d88\u8017\u6bd4\u5bf9\u7167\u7ec4\u9ad8<strong>1402.0\u5343\u5361<\/strong>\uff0895% CI: 950.3\u20131853.8\uff09\u3002<\/li>\n<li><strong>\u75b2\u52b3\uff08MFI\uff09<\/strong>\uff1aUC-MSC\u7ec4\u75b2\u52b3\u8bc4\u5206\u6301\u7eed\u663e\u8457\u4f4e\u4e8e\u5bf9\u7167\u7ec4\u3002<\/li>\n<li><strong>\u6574\u4f53\u5065\u5eb7\u611f\uff08SF-36\uff09<\/strong>\uff1a3\u4e2a\u6708\u65f6\u5e73\u5747\u5dee\u5f02<strong>+22.5\u5206<\/strong>\uff08\u663e\u8457\u6539\u5584\uff09\u3002<\/li>\n<li><strong>\u819d\u5173\u8282\u75bc\u75db\uff08WOMAC\uff09<\/strong>\uff1a9\u4e2a\u6708\u65f6\u624d\u51fa\u73b0\u663e\u8457\u5dee\u5f02\uff0c\u63d0\u793a\u5173\u8282\u4fee\u590d\u53ef\u80fd\u9700\u8981\u66f4\u957f\u89c2\u5bdf\u65f6\u95f4\u3002<\/li>\n<\/ul>\n<p><strong>\u603b\u4f53\u5065\u5eb7\u611f\u77e5\uff1a<\/strong>UC-MSC\u7ec4\u7684\u603b\u4f53\u5065\u5eb7\u611f\u77e5\uff08SF-36\uff09\u660e\u663e\u66f4\u4f18\uff0c3\u4e2a\u6708\u65f6\u5e73\u5747\u5dee\u5f02\u4e3a+22.5\u5206\uff08\u88683\uff09\u3002<\/p>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59732 aligncenter\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409090565.png\" sizes=\"auto, (max-width: 874px) 100vw, 874px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409090565.png 874w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409090565-768x357.png 768w\" alt=\"\" width=\"874\" height=\"406\" title=\"\"><figcaption><\/figcaption><\/figure>\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-59731 aligncenter\" title=\"\u88683\uff1a\u91c7\u7528\u6df7\u5408\u6548\u5e94\u6a21\u578b\uff0c\u4ee5\u610f\u5411\u6cbb\u7597\u4eba\u7fa4\u4e3a\u5bf9\u8c61\uff0c\u5206\u6790 UC-MSC \u7ec4\u548c\u5bf9\u7167\u7ec4\u4e4b\u95f4\u968f\u65f6\u95f4\u63a8\u79fb\u7684\u4e34\u5e8a\u4e3b\u8981\u548c\u6b21\u8981\u7597\u6548\u7ed3\u679c\u3002\" src=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409090325.png\" sizes=\"auto, (max-width: 875px) 100vw, 875px\" srcset=\"https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409090325.png 875w, https:\/\/www.hjtdsm.com\/wp-content\/uploads\/2026\/04\/2026042409090325-768x290.png 768w\" alt=\"\u88683\uff1a\u91c7\u7528\u6df7\u5408\u6548\u5e94\u6a21\u578b\uff0c\u4ee5\u610f\u5411\u6cbb\u7597\u4eba\u7fa4\u4e3a\u5bf9\u8c61\uff0c\u5206\u6790UC-MSC \u7ec4\u548c\u5bf9\u7167\u7ec4\u4e4b\u95f4\u968f\u65f6\u95f4\u63a8\u79fb\u7684\u4e34\u5e8a\u4e3b\u8981\u548c\u6b21\u8981\u7597\u6548\u7ed3\u679c\u3002\" width=\"875\" height=\"330\" \/><figcaption class=\"wp-element-caption\">\u88683\uff1a\u91c7\u7528\u6df7\u5408\u6548\u5e94\u6a21\u578b\uff0c\u4ee5\u610f\u5411\u6cbb\u7597\u4eba\u7fa4\u4e3a\u5bf9\u8c61\uff0c\u5206\u6790 UC-MSC \u7ec4\u548c\u5bf9\u7167\u7ec4\u4e4b\u95f4\u968f\u65f6\u95f4\u63a8\u79fb\u7684\u4e34\u5e8a\u4e3b\u8981\u548c\u6b21\u8981\u7597\u6548\u7ed3\u679c\u3002<\/figcaption><\/figure>\n<p><strong>\u80ba\u529f\u80fd\u4e0e\u5fc3\u529f\u80fd\uff1a<\/strong>\u5728\u968f\u8bbf\u671f\u95f4\u4efb\u4f55\u65f6\u95f4\u70b9\uff0c\u4e24\u7ec4\u95f4FEV1\/FVC\u6bd4\u503c\u53ca\u5de6\u5fc3\u5ba4\u5c04\u8840\u5206\u6570\uff08LVEF\uff09\u5747\u65e0\u7edf\u8ba1\u5b66\u663e\u8457\u5dee\u5f02\u3002<\/p>\n<h3 id=\"ftoc-heading-9\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%83%E3%80%81%E7%94%9F%E7%89%A9%E6%A0%87%E5%BF%97%E7%89%A9%E5%8F%98%E5%8C%96%EF%BC%9A%E6%8F%AD%E7%A4%BA%E5%8F%AF%E8%83%BD%E7%9A%84%E6%B2%BB%E7%96%97%E6%9C%BA%E5%88%B6\"><\/span>\u4e03\u3001\u751f\u7269\u6807\u5fd7\u7269\u53d8\u5316\uff1a\u63ed\u793a\u53ef\u80fd\u7684\u6cbb\u7597\u673a\u5236<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>\u708e\u75c7\u56e0\u5b50\u4e0b\u964d\uff1a<\/strong>UC-MSC\u7ec4\u5728<strong>1\u4e2a\u6708\u548c9\u4e2a\u6708<\/strong>\u65f6\uff0c\u8840\u6d46IL-6\u3001TNF-\u03b1\u3001IL-1\u03b2\u6c34\u5e73\u5747\u663e\u8457\u4f4e\u4e8e\u5bf9\u7167\u7ec4\u3002IL-10\u4e5f\u6709\u6240\u4e0b\u964d\uff0c\u53ef\u80fd\u53cd\u6620\u514d\u75ab\u7a33\u6001\u6062\u590d\uff0c\u800c\u975e\u7b80\u5355\u7684\u6297\u708e\/\u4fc3\u708e\u5e73\u8861\u3002<\/p>\n<p><strong>\u7ec6\u80de\u8870\u8001\u6807\u5fd7\u7269\u964d\u4f4e\uff1a<\/strong>CD3+T\u7ec6\u80de\u4e2d<strong>p16INK4a mRNA\u8868\u8fbe<\/strong>\u5728\u8f93\u6ce8\u540e3\u4e2a\u6708\u663e\u8457\u964d\u4f4e\uff0c\u63d0\u793aMSC\u53ef\u80fd\u6e05\u9664\u8870\u8001\u7ec6\u80de\u6216\u6291\u5236\u8870\u8001\u76f8\u5173\u5206\u6ccc\u8868\u578b\uff08SASP\uff09\u3002<\/p>\n<p><strong>\u7ebf\u7c92\u4f53\u529f\u80fd\u6539\u5584\uff1a<\/strong>\u57286\u4e2a\u6708\u65f6\uff0cUC-MSC\u7ec4\u7684\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de<strong>\u6700\u5927\u547c\u5438\u548c\u50a8\u5907\u547c\u5438\u80fd\u529b<\/strong>\u5747\u663e\u8457\u9ad8\u4e8e\u5bf9\u7167\u7ec4\uff0c\u63a8\u6d4b\u4e0eMSC\u8f6c\u79fb\u5065\u5eb7\u7ebf\u7c92\u4f53\u6709\u5173\u3002<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p><strong>\u6ce8\u610f<\/strong>\uff1ap16INK4a\u964d\u4f4e\u548c\u7ebf\u7c92\u4f53\u529f\u80fd\u6539\u5584\u672a\u6301\u7eed\u81f39\u4e2a\u6708\uff0c\u63d0\u793a<strong>\u7597\u6548\u5b58\u5728\u65f6\u9650\u6027<\/strong>\uff0c\u53ef\u80fd\u9700\u8981\u91cd\u590d\u7ed9\u836f\u3002<\/p><\/blockquote>\n<h3 id=\"ftoc-heading-10\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E5%85%AB%E3%80%81%E6%9C%89%E6%84%8F%E6%80%9D%E7%9A%84%E5%8F%91%E7%8E%B0%EF%BC%9A%E4%BA%9A%E7%BB%84%E5%88%86%E6%9E%90%E2%80%94%E2%80%94%E5%9F%BA%E7%BA%BF%E8%A1%B0%E5%BC%B1%E7%A8%8B%E5%BA%A6%E5%BD%B1%E5%93%8D%E7%96%97%E6%95%88\"><\/span>\u516b\u3001\u6709\u610f\u601d\u7684\u53d1\u73b0\uff1a\u4e9a\u7ec4\u5206\u6790\u2014\u2014\u57fa\u7ebf\u8870\u5f31\u7a0b\u5ea6\u5f71\u54cd\u7597\u6548<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u7814\u7a76\u8005\u6839\u636e\u57fa\u7ebf<strong>\u6162\u6027\u75b2\u52b3\u7efc\u5408\u5f81\u5206\u7ea7\uff08CFS\uff09<\/strong>\u00a0\u5c06\u60a3\u8005\u5206\u4e3a3\u7ea7\uff08\u8f7b\u5ea6\u865a\u5f31\uff09\u30014\u7ea7\uff08\u4e2d\u5ea6\u865a\u5f31\uff09\u30015\u7ea7\uff08\u91cd\u5ea6\u865a\u5f31\uff09\uff0c\u53d1\u73b0\u6cbb\u7597\u6548\u679c\u5b58\u5728\u660e\u663e\u5f02\u8d28\u6027\uff1a<\/p>\n<figure class=\"wp-block-table is-style-stripes\">\n<table class=\"has-fixed-layout\">\n<thead>\n<tr>\n<th>\u7ed3\u5c40\u6307\u6807<\/th>\n<th>CFS 3\u7ea7\uff08\u8f7b\u5ea6\uff09<\/th>\n<th>CFS 4\u7ea7\uff08\u4e2d\u5ea6\uff09<\/th>\n<th>CFS 5\u7ea7\uff08\u91cd\u5ea6\uff09<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>SPPB\u6539\u5584<\/td>\n<td>\u4e2d\u7b49<\/td>\n<td><strong>\u6700\u7a81\u51fa\uff08+1.5\u5206\uff09<\/strong><\/td>\n<td>\u8f83\u5f31<\/td>\n<\/tr>\n<tr>\n<td>\u63e1\u529b\u589e\u52a0<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e2d\u7b49<\/span><\/span><\/span><\/span><\/td>\n<td><strong>\u6700\u7a81\u51fa\uff08+4.5kg\uff09<\/strong><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8f83\u5f31<\/span><\/span><\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u4f53\u529b\u6d3b\u52a8\u6539\u5584<\/td>\n<td>\u6709\u9650<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e2d\u7b49<\/span><\/span><\/span><\/span><\/td>\n<td><strong>\u6700\u7a81\u51fa\uff08+1871\u5343\u5361\/\u5468\uff09<\/strong><\/td>\n<\/tr>\n<tr>\n<td>\u4e00\u822c\u5065\u5eb7\u611f(SF-36)<\/td>\n<td>\u7a33\u5b9a<\/td>\n<td><strong>\u6700\u7a33\u5b9a\uff08+24.7\u5206\uff09<\/strong><\/td>\n<td>\u6ce2\u52a8<\/td>\n<\/tr>\n<tr>\n<td>p16INK4a\u4e0b\u964d<\/td>\n<td><strong>\u660e\u663e<\/strong><\/td>\n<td>\u4e0d\u660e\u663e<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e0d\u660e\u663e<\/span><\/span><\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u65e9\u671f\u6297\u708e\u53cd\u5e94(IL-6\u4e0b\u964d)<\/td>\n<td>\u8f83\u6162<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e2d\u7b49<\/span><\/span><\/span><\/span><\/td>\n<td><strong>\u6700\u65e9\u3001\u6700\u663e\u8457<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p><strong>\u4e34\u5e8a\u542f\u793a<\/strong>::<\/p>\n<ul class=\"wp-block-list\">\n<li>\u4e2d\u5ea6\u8870\u5f31\uff08CFS 4\u7ea7\uff09\u60a3\u8005\u5728\u8eab\u4f53\u529f\u80fd\u548c\u6574\u4f53\u5065\u5eb7\u611f\u4e0a<strong>\u77ed\u671f\u83b7\u76ca\u6700\u5927<\/strong>\uff0c\u53ef\u80fd\u5904\u4e8e\u201c\u6700\u4f73\u6cbb\u7597\u7a97\u53e3\u201d\u3002<\/li>\n<li>\u91cd\u5ea6\u8870\u5f31\uff08CFS 5\u7ea7\uff09\u60a3\u8005\u867d\u7136\u8eab\u4f53\u529f\u80fd\u6539\u5584\u4e0d\u7a81\u51fa\uff0c\u4f46<strong>\u4f53\u529b\u6d3b\u52a8\u548c\u6297\u708e\u53cd\u5e94\u83b7\u76ca\u660e\u663e<\/strong>\uff0c\u8bf4\u660e\u4ecd\u53ef\u53d7\u76ca\u3002<\/li>\n<li>\u8f7b\u5ea6\u8870\u5f31\uff08CFS 3\u7ea7\uff09\u60a3\u8005\u4e3b\u8981\u4f53\u73b0\u4e3a<strong>\u7ec6\u80de\u8870\u8001\u6807\u5fd7\u7269\u6539\u5584<\/strong>\uff0c\u63d0\u793a\u66f4\u65e9\u5e72\u9884\u53ef\u80fd\u5ef6\u7f13\u8870\u5f31\u8fdb\u5c55\u3002<\/li>\n<\/ul>\n<h3 id=\"ftoc-heading-11\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E4%B9%9D%E3%80%81%E4%BA%9A%E7%BB%84%E5%88%86%E6%9E%90%E3%80%81%E5%B1%80%E9%99%90%E6%80%A7%E5%8F%8A%E6%9C%AA%E6%9D%A5%E5%BB%BA%E8%AE%AE\"><\/span>\u4e5d\u3001<strong>\u4e9a\u7ec4\u5206\u6790\u3001\u5c40\u9650\u6027\u53ca\u672a\u6765\u5efa\u8bae<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u4e9a\u7ec4\u5206\u6790\u53d1\u73b0\uff1a\u57fa\u7ebf\u8870\u5f31\u7a0b\u5ea6\u53ef\u8c03\u8282\u6cbb\u7597\u6548\u679c\u3002<strong>\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u865a\u5f31\uff08CFS 3-4\uff09\u60a3\u8005\u8868\u73b0\u51fa\u6301\u7eed\u7684\u529f\u80fd\u83b7\u76ca\uff0c\u800c\u91cd\u5ea6\u865a\u5f31\uff08CFS 5\uff09\u60a3\u8005\u5728\u5173\u8282\u529f\u80fd\u53caLVEF\u53c2\u6570\u4e0a\u53cd\u5e94\u4e0d\u540c\uff0c\u63d0\u793a\u5b58\u5728\u201c\u6cbb\u7597\u7a97\u53e3\u201d\u2014\u2014\u5728\u751f\u7406\u50a8\u5907\u4e25\u91cd\u8017\u7aed\u524d\u5e72\u9884\u53ef\u80fd\u66f4\u4e3a\u6709\u6548<\/strong>\u3002\u751f\u7269\u5b66\u53cd\u5e94\u4ea6\u5b58\u5728\u5f02\u8d28\u6027\uff1ap16INK4a\u548c\u7ebf\u7c92\u4f53\u529f\u80fd\u7684\u6539\u5584\u5728CFS 3\u7ea7\u6700\u663e\u8457\uff0c\u800c\u708e\u75c7\u6807\u5fd7\u7269\u5728CFS 5\u7ea7\u65e9\u671f\u4e0b\u964d\u5e45\u5ea6\u6700\u5927\u3002<\/p>\n<p><strong>\u672c\u7814\u7a76\u5b58\u5728\u4ee5\u4e0b\u5c40\u9650\uff1a<\/strong>\u5355\u4e2d\u5fc3\u8bbe\u8ba1\uff1b\u5f00\u653e\u6807\u7b7e\u53ef\u80fd\u5bfc\u81f4\u68c0\u6d4b\u504f\u501a\uff08\u4f46\u901a\u8fc7\u751f\u7406\u7ec8\u70b9\u76f2\u6cd5\u8bc4\u4f30\u548c\u5ba2\u89c2\u751f\u7269\u6807\u5fd7\u7269\u4e88\u4ee5\u90e8\u5206\u62b5\u6d88\uff09\uff1b\u6837\u672c\u91cf\u5bf9\u7f55\u89c1\u4e8b\u4ef6\u68c0\u6d4b\u4e0d\u8db3\uff1b\u4e9a\u7ec4\u5206\u6790\u548c\u63a2\u7d22\u6027\u751f\u7269\u6807\u5fd7\u7269\u5206\u6790\u4ec5\u5177\u5047\u8bbe\u751f\u6210\u6027\u8d28\u3002\u56e0\u4f26\u7406\u8003\u8651\u672a\u80fd\u8bbe\u7f6e\u5b89\u6170\u5242\u5bf9\u7167\u5047\u8f93\u6ce8\uff0c\u4f46\u5ba2\u89c2\u6307\u6807\u652f\u6301\u4e3b\u8981\u7ed3\u8bba\u3002<\/p>\n<p><strong>\u672a\u6765\u5efa\u8bae\uff1a<\/strong>\u8bc4\u4f30\u91cd\u590d\u6216\u7ef4\u6301\u7ed9\u836f\u65b9\u6848\u4ee5\u5ef6\u957f\u7597\u6548\uff1b\u63a2\u7d22MSC\u8054\u5408\u8fd0\u52a8\u6216\u4ee3\u8c22\u652f\u6301\u7b49\u5e72\u9884\u7b56\u7565\uff1b\u5728\u66f4\u5927\u89c4\u6a21\u3001\u591a\u4e2d\u5fc3\u8bd5\u9a8c\u4e2d\u9a8c\u8bc1\u5f53\u524d\u53d1\u73b0\u3002<\/p>\n<h3 id=\"ftoc-heading-12\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E5%8D%81%E3%80%81%E5%B8%B8%E8%A7%81%E9%97%AE%E9%A2%98%E8%A7%A3%E7%AD%94%EF%BC%88FAQ%EF%BC%89\"><\/span>\u5341\u3001\u5e38\u89c1\u95ee\u9898\u89e3\u7b54\uff08FAQ\uff09<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<h3><span class=\"ez-toc-section\" id=\"%E9%97%AE1%EF%BC%9A%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%80%81%E5%B9%B4%E4%BA%BA%E8%A1%B0%E5%BC%B1%E7%9B%AE%E5%89%8D%E6%98%AF%E6%88%90%E7%86%9F%E6%8A%80%E6%9C%AF%E5%90%97%EF%BC%9F%E6%88%91%E7%88%B6%E6%AF%8D%E8%83%BD%E7%94%A8%E4%B8%8A%E5%90%97%EF%BC%9F\"><\/span>\u95ee1\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u8001\u5e74\u4eba\u8870\u5f31\u76ee\u524d\u662f\u6210\u719f\u6280\u672f\u5417\uff1f\u6211\u7236\u6bcd\u80fd\u7528\u4e0a\u5417\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54\uff1a<\/strong>\u76ee\u524d<strong>\u5c1a\u672a\u6210\u719f<\/strong>\u3002\u8fd9\u9879\u7814\u7a76\u662fII\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bc1\u5b9e\u4e86\u5b89\u5168\u6027\u548c\u521d\u6b65\u6709\u6548\u6027\uff0c\u4f46<strong>\u5c1a\u672a\u83b7\u6279\u6210\u4e3a\u5e38\u89c4\u6cbb\u7597<\/strong>\u3002\u5168\u7403\u6ca1\u6709\u4efb\u4f55\u56fd\u5bb6\u6b63\u5f0f\u6279\u51c6\u5e72\u7ec6\u80de\u7597\u6cd5\u7528\u4e8e\u8870\u5f31\u7684\u4e34\u5e8a\u5e38\u89c4\u5e94\u7528\u3002\u5982\u679c\u67d0\u4e9b\u673a\u6784\u58f0\u79f0\u201c\u5df2\u6210\u719f\u3001\u53ef\u6536\u8d39\u6cbb\u7597\u201d\uff0c\u8bf7\u9ad8\u5ea6\u8b66\u60d5\uff0c\u5f88\u53ef\u80fd\u662f\u975e\u6cd5\u6216\u865a\u5047\u5ba3\u4f20\u3002\u6b63\u89c4\u7684\u5e72\u7ec6\u80de\u6cbb\u7597\u8870\u5f31\u76ee\u524d<strong>\u4ec5\u5728\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5<\/strong>\uff0c\u4e14\u4e0d\u5411\u53d7\u8bd5\u8005\u6536\u8d39\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E9%97%AE2%EF%BC%9A%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%A1%B0%E5%BC%B1%E7%9C%9F%E7%9A%84%E6%9C%89%E6%95%88%E5%90%97%EF%BC%9F%E8%83%BD%E9%80%86%E8%BD%AC%E8%A1%B0%E8%80%81%E5%90%97%EF%BC%9F\"><\/span>\u95ee2\uff1a\u5e72\u7ec6\u80de\u6cbb\u7597\u8870\u5f31\u771f\u7684\u6709\u6548\u5417\uff1f\u80fd\u9006\u8f6c\u8870\u8001\u5417\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54\uff1a<\/strong>\u6839\u636e\u8fd9\u9879\u6700\u65b0II\u671f\u8bd5\u9a8c\uff0cUC-MSC\u6cbb\u7597\u5728<strong>3-9\u4e2a\u6708\u5185<\/strong>\u663e\u8457\u6539\u5584\u4e86\u8870\u5f31\u8001\u4eba\u7684<strong>\u8eab\u4f53\u529f\u80fd\uff08SPPB\u3001\u6b65\u901f\u3001\u63e1\u529b\uff09\u3001\u4f53\u529b\u6d3b\u52a8\u6c34\u5e73\u3001\u75b2\u52b3\u7a0b\u5ea6\u548c\u751f\u6d3b\u8d28\u91cf<\/strong>\uff0c\u6548\u679c\u4f18\u4e8e\u5355\u7eaf\u53e3\u670d\u8865\u5145\u5242\u3002\u4f46\u5b83<strong>\u4e0d\u80fd\u201c\u9006\u8f6c\u8870\u8001\u201d<\/strong>\u00a0\uff0c\u4e5f\u4e0d\u80fd\u8ba9\u8001\u4eba\u6062\u590d\u5e74\u8f7b\u65f6\u7684\u72b6\u6001\u3002\u5b83\u53ef\u80fd\u51cf\u7f13\u529f\u80fd\u8870\u9000\u3001\u964d\u4f4e\u8dcc\u5012\u548c\u4f4f\u9662\u98ce\u9669\u3002\u957f\u671f\u7597\u6548\uff081\u5e74\u4ee5\u4e0a\uff09\u5c1a\u9700\u66f4\u591a\u7814\u7a76\u8bc1\u5b9e\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E9%97%AE3%EF%BC%9A%E6%B2%BB%E7%96%97%E6%9C%89%E5%89%AF%E4%BD%9C%E7%94%A8%E5%90%97%EF%BC%9F%E5%AE%89%E4%B8%8D%E5%AE%89%E5%85%A8%EF%BC%9F\"><\/span>\u95ee3\uff1a\u6cbb\u7597\u6709\u526f\u4f5c\u7528\u5417\uff1f\u5b89\u4e0d\u5b89\u5168\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54\uff1a<\/strong>\u672c\u7814\u7a76\u672a\u53d1\u751f\u4efb\u4f55\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff08\u6b7b\u4ea1\u3001\u8840\u6813\u3001\u6b8b\u75be\u7b49\uff09\u3002\u5e38\u89c1\u4e0d\u826f\u53cd\u5e94\u4e3a<strong>\u8f7b\u5fae\u5934\u75db\u3001\u5934\u6655\u3001\u80f8\u90e8\u4e0d\u9002<\/strong>\uff0c\u53d1\u751f\u7387\u4e3a26%\uff08\u6cbb\u7597\u7ec4\uff09\uff0c\u6240\u6709\u75c7\u72b6\u5747\u81ea\u884c\u7f13\u89e3\uff0c\u65e0\u540e\u9057\u75c7\u3002\u76f8\u6bd4\u800c\u8a00\uff0c\u5bf9\u7167\u7ec4\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\u4e3a8.1%\u3002\u603b\u4f53\u4e0a\uff0c<strong>UC-MSC\u9759\u8109\u8f93\u6ce8\u5728\u8001\u5e74\u8870\u5f31\u60a3\u8005\u4e2d\u663e\u793a\u826f\u597d\u7684\u77ed\u671f\u5b89\u5168\u6027<\/strong>\u3002\u4f46\u957f\u671f\u5b89\u5168\u6027\uff08\u5982\u81f4\u7624\u98ce\u9669\uff09\u4ecd\u9700\u66f4\u957f\u65f6\u95f4\u968f\u8bbf\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E9%97%AE4%EF%BC%9A%E5%A4%A7%E6%A6%82%E9%9C%80%E8%A6%81%E5%A4%9A%E5%B0%91%E9%92%B1%EF%BC%9F%E5%8C%BB%E4%BF%9D%E8%83%BD%E6%8A%A5%E9%94%80%E5%90%97%EF%BC%9F\"><\/span>\u95ee4\uff1a\u5927\u6982\u9700\u8981\u591a\u5c11\u94b1\uff1f\u533b\u4fdd\u80fd\u62a5\u9500\u5417\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54\uff1a<\/strong>\u7531\u4e8e\u8be5\u7597\u6cd5\u5c1a\u672a\u83b7\u6279\u4e0a\u5e02\uff0c\u6ca1\u6709\u5b98\u65b9\u5b9a\u4ef7\u3002\u5728\u975e\u6b63\u89c4\u673a\u6784\u6216\u6d77\u5916\u9879\u76ee\u4e2d\uff0c\u62a5\u4ef7\u53ef\u80fd<strong>\u6bcf\u7597\u7a0b10-30\u4e07\u5143\u4eba\u6c11\u5e01<\/strong>\uff0c\u4e14\u533b\u4fdd\u5b8c\u5168\u4e0d\u62a5\u9500\u3002<strong>\u518d\u6b21\u5f3a\u8c03\uff1a\u4efb\u4f55\u6536\u8d39\u7684\u5e72\u7ec6\u80de\u6cbb\u7597\u8870\u5f31\u5747\u4e0d\u5c5e\u4e8e\u89c4\u8303\u7684\u533b\u7597\u884c\u4e3a<\/strong>\u3002\u5efa\u8bae\u60a8\u5173\u6ce8\u6b63\u89c4\u533b\u9662\u5f00\u5c55\u7684\u4e34\u5e8a\u8bd5\u9a8c\u62db\u52df\u4fe1\u606f\uff08\u514d\u8d39\u53c2\u52a0\uff09\u3002\u5728\u83b7\u6279\u524d\uff0c\u8bf7\u5c06\u8d44\u91d1\u7528\u4e8e\u5df2\u8bc1\u5b9e\u7684\u5e72\u9884\u624b\u6bb5\uff08\u8425\u517b\u3001\u8fd0\u52a8\u3001\u8001\u5e74\u7efc\u5408\u8bc4\u4f30\uff09\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E9%97%AE5%EF%BC%9A%E5%9C%A8%E5%93%AA%E9%87%8C%E5%8F%AF%E4%BB%A5%E5%8F%82%E5%8A%A0%E6%AD%A3%E8%A7%84%E7%9A%84%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E8%A1%B0%E5%BC%B1%E7%9A%84%E4%B8%B4%E5%BA%8A%E8%AF%95%E9%AA%8C%EF%BC%9F\"><\/span>\u95ee5\uff1a\u5728\u54ea\u91cc\u53ef\u4ee5\u53c2\u52a0\u6b63\u89c4\u7684\u5e72\u7ec6\u80de\u6cbb\u7597\u8870\u5f31\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54\uff1a<\/strong>\u60a8\u53ef\u4ee5\u5b9a\u671f\u67e5\u8be2\uff1a<\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u4e2d\u56fd<\/strong>\uff1a\u4e2d\u56fd\u4e34\u5e8a\u8bd5\u9a8c\u6ce8\u518c\u4e2d\u5fc3\uff08<a href=\"https:\/\/www.chictr.org.cn\/\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">www.chictr.org.cn<\/a>\uff09<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u7f8e\u56fd<\/strong>::<a href=\"https:\/\/clinicaltrials.gov\/\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">ClinicalTrials.gov<\/a><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>\u6b27\u6d32<\/strong>\uff1a\u6b27\u76df\u4e34\u5e8a\u8bd5\u9a8c\u6ce8\u518c\u5e93<\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\">\u641c\u7d22\u5173\u952e\u8bcd\uff1a\u201cfrailty + mesenchymal stem cell\u201d\u6216\u201c\u8870\u5f31 + \u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u201d\uff0c\u7b5b\u9009\u201cRecruiting\u201d\u72b6\u6001\u3002<strong>\u6240\u6709\u6b63\u89c4\u4e34\u5e8a\u8bd5\u9a8c\u5747\u4e0d\u6536\u8d39<\/strong>\uff0c\u4e14\u63d0\u4f9b\u8be6\u7ec6\u77e5\u60c5\u540c\u610f\u548c\u4fdd\u9669\u4fdd\u969c\u3002\u5982\u679c\u8981\u6c42\u60a8\u652f\u4ed8\u201c\u6cbb\u7597\u8d39\u201d\uff0c\u4e00\u5b9a\u662f\u9a97\u5c40\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E9%97%AE6%EF%BC%9A%E5%92%8C%E8%BF%90%E5%8A%A8%E3%80%81%E8%90%A5%E5%85%BB%E5%B9%B2%E9%A2%84%E7%9B%B8%E6%AF%94%EF%BC%8C%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%E7%9A%84%E4%BC%98%E5%8A%BF%E5%9C%A8%E5%93%AA%E9%87%8C%EF%BC%9F\"><\/span>\u95ee6\uff1a\u548c\u8fd0\u52a8\u3001\u8425\u517b\u5e72\u9884\u76f8\u6bd4\uff0c\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4f18\u52bf\u5728\u54ea\u91cc\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54\uff1a<\/strong>\u00a0\u8fd0\u52a8\u4e0e\u8425\u517b\u662f\u8870\u5f31\u7684<strong>\u57fa\u7840\u4e00\u7ebf\u5e72\u9884<\/strong>\uff0c\u8bc1\u636e\u5145\u5206\u3001\u6210\u672c\u4f4e\u3001\u65e0\u98ce\u9669\uff0c\u5e94\u4f18\u5148\u91c7\u7528\u3002\u4f46\u5f88\u591a\u8870\u5f31\u8001\u4eba\u56e0\u8eab\u4f53\u539f\u56e0\u65e0\u6cd5\u575a\u6301\u8db3\u91cf\u8fd0\u52a8\uff0c\u6216\u5438\u6536\u8425\u517b\u80fd\u529b\u5dee\u3002\u5e72\u7ec6\u80de\u7597\u6cd5\u7684\u6f5c\u5728\u4f18\u52bf\u5728\u4e8e<strong>\u4ece\u5168\u8eab\u7cfb\u7edf\u5c42\u9762\u8c03\u8282\u708e\u75c7\u3001\u6539\u5584\u808c\u8089\u4ee3\u8c22\u548c\u7ebf\u7c92\u4f53\u529f\u80fd<\/strong>\uff0c\u53ef\u80fd\u5bf9\u90a3\u4e9b\u5bf9\u5e38\u89c4\u5e72\u9884\u53cd\u5e94\u4e0d\u4f73\u7684\u60a3\u8005\u63d0\u4f9b\u989d\u5916\u83b7\u76ca\u3002\u76ee\u524d<strong>\u4e0d\u5efa\u8bae\u7528\u5e72\u7ec6\u80de\u66ff\u4ee3\u57fa\u7840\u5e72\u9884<\/strong>\uff0c\u800c\u662f\u4f5c\u4e3a\u8865\u5145\u6216\u540e\u7eed\u7814\u7a76\u65b9\u5411\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E9%97%AE7%EF%BC%9A%E5%93%AA%E4%BA%9B%E8%80%81%E5%B9%B4%E4%BA%BA%E4%B8%8D%E9%80%82%E5%90%88%E5%B0%9D%E8%AF%95%E5%B9%B2%E7%BB%86%E8%83%9E%E6%B2%BB%E7%96%97%EF%BC%9F\"><\/span>\u95ee7\uff1a\u54ea\u4e9b\u8001\u5e74\u4eba\u4e0d\u9002\u5408\u5c1d\u8bd5\u5e72\u7ec6\u80de\u6cbb\u7597\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54\uff1a<\/strong>\u6839\u636e\u8be5\u8bd5\u9a8c\u6392\u9664\u6807\u51c6\uff0c\u4ee5\u4e0b\u60c5\u51b5\u4e0d\u9002\u5408\uff1a<\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\">\u4e25\u91cd\u8ba4\u77e5\u969c\u788d\uff08MMSE\u226420\uff09<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\">\u4e25\u91cd\u809d\u80be\u529f\u80fd\u4e0d\u5168\u3001\u4e25\u91cd\u8d2b\u8840\uff08Hb&lt;90g\/L\uff09\u3001\u4e25\u91cd\u8425\u517b\u4e0d\u826f\uff08\u767d\u86cb\u767d&lt;30g\/L\uff09<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\">\u6d3b\u52a8\u6027\u6076\u6027\u80bf\u7624\u6216\u8fd15\u5e74\u5185\u6709\u6076\u6027\u80bf\u7624\u53f2\uff08\u975e\u9ed1\u8272\u7d20\u7624\u76ae\u80a4\u764c\u9664\u5916\uff09<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\">\u9884\u671f\u5bff\u547d\u4e0d\u8db31\u5e74<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\">\u4e25\u91cd\u5fc3\u8870\uff08NYHA III\/IV\u7ea7\uff09\u3001\u672a\u63a7\u5236\u7684\u9ad8\u8840\u538b\u3001\u8fd1\u671f\u5fc3\u6897\u6216\u4e2d\u98ce<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\">\u514d\u75ab\u6291\u5236\u6216\u6d3b\u52a8\u6027\u611f\u67d3<\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\">\u5177\u4f53\u662f\u5426\u9002\u5408\uff0c\u5fc5\u987b\u7531\u4e34\u5e8a\u533b\u751f\u8bc4\u4f30\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E9%97%AE8%EF%BC%9A%E4%B8%80%E6%AC%A1%E6%B2%BB%E7%96%97%E8%83%BD%E7%AE%A1%E5%A4%9A%E4%B9%85%EF%BC%9F%E9%9C%80%E8%A6%81%E9%87%8D%E5%A4%8D%E8%BE%93%E6%B3%A8%E5%90%97%EF%BC%9F\"><\/span>\u95ee8\uff1a\u4e00\u6b21\u6cbb\u7597\u80fd\u7ba1\u591a\u4e45\uff1f\u9700\u8981\u91cd\u590d\u8f93\u6ce8\u5417\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>\u7b54\uff1a<\/strong>\u672c\u7814\u7a76\u91c7\u7528<strong>\u4e24\u6b21\u8f93\u6ce8\uff08\u95f4\u96943\u4e2a\u6708\uff09<\/strong>\uff0c\u968f\u8bbf\u81f39\u4e2a\u6708\u65f6\u90e8\u5206\u6539\u5584\uff08\u5982SPPB\u3001\u63e1\u529b\uff09\u4ecd\u4f18\u4e8e\u5bf9\u7167\u7ec4\uff0c\u4f46\u751f\u7269\u6807\u5fd7\u7269\uff08p16INK4a\u3001\u7ebf\u7c92\u4f53\u529f\u80fd\uff09\u7684\u6539\u5584\u57289\u4e2a\u6708\u65f6\u5df2\u4e0d\u663e\u8457\uff0c\u63d0\u793a<strong>\u7597\u6548\u53ef\u80fd\u6301\u7eed\u7ea66-9\u4e2a\u6708<\/strong>\u3002\u672a\u6765\u7684\u7814\u7a76\u53ef\u80fd\u4f1a\u63a2\u7d22<strong>\u6bcf6-12\u4e2a\u6708\u91cd\u590d\u8f93\u6ce8<\/strong>\u6216\u957f\u671f\u7ef4\u6301\u65b9\u6848\u3002\u76ee\u524d\u5c1a\u65e0\u6807\u51c6\u65b9\u6848\u3002<\/p>\n<h3 id=\"ftoc-heading-13\" class=\"wp-block-heading ftwp-heading\"><span class=\"ez-toc-section\" id=\"%E5%8D%81%E4%B8%80%E3%80%81%E6%80%BB%E7%BB%93%E4%B8%8E%E5%B1%95%E6%9C%9B\"><\/span>\u5341\u4e00\u3001\u603b\u7ed3\u4e0e\u5c55\u671b<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u8fd9\u9879\u53d1\u8868\u4e8e2026\u5e744\u670824\u65e5\u300aeBioMedicine\u300b\u7684II\u671f\u968f\u673a\u8bd5\u9a8c\u63d0\u4f9b\u4e86\u8fc4\u4eca\u4e3a\u6b62\u5173\u4e8e<strong>\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8001\u5e74\u4eba\u8870\u5f31<\/strong>\u8f83\u9ad8\u7ea7\u522b\u7684\u4e34\u5e8a\u8bc1\u636e\uff1a<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u5b89\u5168\u6027\u826f\u597d<\/strong>\uff1a\u65e0\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff0c\u8010\u53d7\u6027\u597d<\/li>\n<li><strong>\u6709\u6548\u6027\u663e\u8457<\/strong>\uff1a\u6539\u5584\u8eab\u4f53\u529f\u80fd\u3001\u808c\u8089\u529b\u91cf\u3001\u4f53\u529b\u6d3b\u52a8\u3001\u75b2\u52b3\u53ca\u751f\u6d3b\u8d28\u91cf<\/li>\n<li><strong>\u673a\u5236\u5408\u7406<\/strong>\uff1a\u964d\u4f4e\u708e\u75c7\u3001\u51cf\u8f7b\u7ec6\u80de\u8870\u8001\u3001\u6539\u5584\u7ebf\u7c92\u4f53\u529f\u80fd<\/li>\n<li><strong>\u4e9a\u7ec4\u5f02\u8d28\u6027<\/strong>\uff1a\u4e2d\u5ea6\u8870\u5f31\uff08CFS 4\u7ea7\uff09\u60a3\u8005\u83b7\u76ca\u6700\u5927<\/li>\n<\/ul>\n<p>\u8fd9\u4e9b\u53d1\u73b0\u4e3a\u5f00\u5c55<strong>\u66f4\u5927\u89c4\u6a21\u3001\u53cc\u76f2\u3001\u591a\u4e2d\u5fc3III\u671f\u8bd5\u9a8c<\/strong>\u5960\u5b9a\u4e86\u575a\u5b9e\u57fa\u7840\u3002\u5728\u7b49\u5f85\u66f4\u5145\u5206\u8bc1\u636e\u7684\u540c\u65f6\uff0c\u8001\u5e74\u4eba\u548c\u5bb6\u5c5e\u5e94<strong>\u9996\u9009\u5df2\u88ab\u9a8c\u8bc1\u7684\u5e72\u9884\u63aa\u65bd\uff08\u8fd0\u52a8\u3001\u8425\u517b\u3001\u6162\u75c5\u7ba1\u7406\uff09<\/strong>\uff0c\u5e76\u5bf9\u5e72\u7ec6\u80de\u7597\u6cd5\u4fdd\u6301\u7406\u6027\u671f\u5f85\u2014\u2014\u5b83\u53ef\u80fd\u5728\u672a\u67655-10\u5e74\u5185\u6210\u4e3a\u8870\u5f31\u6cbb\u7597\u7684\u65b0\u9009\u9879\uff0c\u4f46\u7edd\u4e0d\u662f\u4eca\u5929\u7684\u201c\u795e\u836f\u201d\u3002<\/p>\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u53c2\u8003\u8d44\u6599<\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">[1] Nguyen L, Nguyen K, Dao L, et al. \u5f02\u4f53\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u8f93\u6ce8\u6cbb\u7597\u8870\u5f31\u75c7\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\uff1a\u4e00\u9879 2 \u671f\u5355\u4e2d\u5fc3\u968f\u673a\u5f00\u653e\u6807\u7b7e\u5bf9\u7167\u8bd5\u9a8c\u3002eBioMedicine\u00a0 \uff0c <\/span><\/span><em><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2026<\/span><\/span><\/em><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff1b12\u3002<\/span><\/span><\/p>\n<p><a href=\"https:\/\/www.thelancet.com\/journals\/ebiom\/article\/PIIS2352-3964(26)00150-7\/fulltext#tbl1\" target=\"_blank\" rel=\"nofollow noopener\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">https:\/\/www.thelancet.com\/journals\/ebiom\/article\/PIIS2352-3964(26)00150-7\/fulltext#tbl1<\/span><\/span><\/span><\/span><\/a><\/p>\n<hr class=\"wp-block-separator has-alpha-channel-opacity\" \/>\n<p><strong>\u514d\u8d23\u8bf4\u660e<\/strong>\uff1a\u672c\u6587\u4ec5\u7528\u4e8e\u4f20\u64ad\u79d1\u666e\u77e5\u8bc6\uff0c\u5206\u4eab\u884c\u4e1a\u89c2\u70b9\uff0c\u4e0d\u6784\u6210\u4efb\u4f55\u4e34\u5e8a\u8bca\u65ad\u5efa\u8bae\u3002\u672c\u6587\u5185\u5bb9\u4e0d\u80fd\u66ff\u4ee3\u533b\u751f\u6216\u836f\u5242\u5e08\u7684\u4e13\u4e1a\u5efa\u8bae\u3002\u5982\u6709\u5177\u4f53\u533b\u7597\u9700\u6c42\uff0c\u8bf7\u52a1\u5fc5\u54a8\u8be2\u6b63\u89c4\u533b\u7597\u673a\u6784\u4e13\u79d1\u533b\u751f\u3002\u676d\u5409\u5e72\u7ec6\u80de\u6240\u53d1\u5e03\u7684\u4fe1\u606f\u4ec5\u4f9b\u53c2\u8003\u3002\u5982\u6709\u7248\u6743\u7b49\u7591\u95ee\uff0c\u8bf7\u968f\u65f6\u8054\u7cfb\u3002<\/p><\/blockquote>","protected":false},"excerpt":{"rendered":"<p>Meta\u63cf\u8ff0\uff1a\u300aeBioMedicine\u300b2026\u5e74\u6700\u65b0II\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff1a\u9759\u8109\u8f93\u6ce8\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8001\u5e74\u8870\u5f31\u7efc [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[76],"tags":[284,202,178],"_links":{"self":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21907"}],"collection":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/comments?post=21907"}],"version-history":[{"count":2,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21907\/revisions"}],"predecessor-version":[{"id":21909,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/posts\/21907\/revisions\/21909"}],"wp:attachment":[{"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/media?parent=21907"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/categories?post=21907"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hjtdsm.cn\/en\/wp-json\/wp\/v2\/tags?post=21907"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}